RESULTS OF THE STUDY OF TYPHOID VACCINES IN FOUR CONTROLLED FIELD TRIALS IN THE USSR. In field trials of typhoid vaccine in the USSR, a comparison was made of the effectiveness of chemical, heat-killed, and alcoholized vaccines. All of them conferred protection if administered in sufficient dosage, and variations in effectiveness could usually be traced to size of dosage. The heat-killed vaccine, however, appeared to be significantly more effective than the others. The immunological history of a vaccinated person apparently had no essential influence on the effectiveness of a vaccine, and the data indicated that two doses of the vaccine conferred no greater protection than one.


THE PRESENT STATUS OF FIELD AND LABORATORY STUDIES OF TYPHOID AND PARATYPHOID VACCINES WITH SPECIAL REFERENCE TO STUDIES SPONSORED BY WORLD HEALTH ORGANIZATION. The authors present a summary of the information yielded by a number of collaborative field and laboratory studies of typhoid vaccines conducted under the auspices of the World Health Organization, comparing, in particular, the results of various controlled field trials carried out in British Guiana, Poland, the USSR and Yugoslavia, and attempting to evaluate the effectiveness of the vaccines in man.Acetone-inactivated typhoid vaccine, which has been established as an international reference preparation, has been proved in field trials to be of a high degree of effectiveness and to confer protection of long duration.Comparison of the results of the field trials with those of laboratory studies indicate that further research is needed in order to develop a test or tests the results of which can be fully correlated with the effectiveness of typhoid vaccines as demonstrated in man.Reference is also made to field studies of paratyphoid vaccines.


EVALUATION OF TYPHOID VACCINES IN THE LABORATORY AND IN A CONTROLLED FIELD TRIAL IN POLAND. PRELIMINARY REPORT. In 1961 a controlled field trial of anti-typhoid vaccines was carried out in 25 regions in Poland. Four types of vaccine were studied: (1) bacterial acetone-killed and -dried vaccine (two kinds), (2) bacterial formol-killed phenol-preserved vaccine, (3) Westphal's endotoxin adsorbed on aluminium hydroxide, and (4) Grasset's vaccine (autolysate of typhoid bacilli adsorbed on aluminium hydroxide). The control vaccine was tetanus toxoid. A total of 690 655 persons received two inoculations. Prior to the field trial, laboratory tests were carried out on the vaccines, postvaccinal reactions were studied, and a serological examination was made of randomly selected blood samples. The vaccination was followed by a two-year survey of cases of typhoid and other diseases. Among children aged 5-14 years, the formol-killed phenol-preserved vaccine was found to be the most effective and Grasset's vaccine the least. Among adults aged 15-60 years, no conclusive evidence for the effectiveness of the vaccines could be obtained owing to the small number of cases. This may be due to the maintenance of immunity through repeated annual vaccination with bacterial vaccines.


TRAFFIC CONTROL.

TRAFFIC CONTROL.


LABORATORY TESTS ON THE EFFECTIVENESS OF ORAL VACCINATION OF YOUNG CHILDREN AGAINST TYPHOID AND PARATYPHOID A AND B. In Romania, pre-school children are excluded from subcutaneous inoculation with typhoid and paratyphoid A and B vaccine. The authors have therefore investigated the possibility of giving them an oral vaccine. Laboratory tests were carried out on 30 children from 3 to 7 years of age. Samples of blood serum were collected before and after vaccination and subsequently tested for (1) seroprotection in chick embryos, (2) seroprotection in white mice, (3) titration of the agglutinating antibodies, and (4) electrophoretic pattern.The results obtained showed that the oral administration of the vaccine can, under the conditions used in the test, afford a considerable degree of protection to young children.


CHAIRSIDE EFFICIENCY USING MOBILE CABINETS AND AUXILIARY EQUIPMENT: A PROGRESS REPORT.


EFFICIENT PATIENT CONTROL.

EFFICIENT PATIENT CONTROL.


THE SELECTION AND USE OF OPERATOR'S STOOLS AND CONTOUR CHAIRS.


HOW TO USE PERSONNEL EFFECTIVELY.

HOW TO USE PERSONNEL EFFECTIVELY.


SIMPLIFIED FULL COVERAGE PREPARATIONS.

SIMPLIFIED FULL COVERAGE PREPARATIONS.


WORK SIMPLIFICATION AND EFFICIENCY IN PERIODONTAL PRACTICE.


EFFICIENT RESTORATIVE PROCEDURES.

EFFICIENT RESTORATIVE PROCEDURES.


HEALTH AND POLITICS: THE BRITISH PHYSICAL DETERIORATION REPORT OF 1904.


EFFICIENT ENDODONTIC PROCEDURES WITH THE USE OF THE PRESSURE SYRINGE.


EFFICIENT VITAL PULP THERAPY.

EFFICIENT VITAL PULP THERAPY.


ORAL DIAGNOSIS AND TREATMENT PLANNING.

ORAL DIAGNOSIS AND TREATMENT PLANNING.


THE ROLE OF BIOPSY AND CYTOLOGY IN ORAL DIAGNOSIS.


PREVENTION AND CONSERVATION IN RESTORATIVE DENTISTRY. I.


PREVENTIVE PERIODONTICS.

PREVENTIVE PERIODONTICS.


PREVENTION AND CONSERVATION IN RESTORATIVE DENTISTRY. II.


ATTITUDES TOWARDS "SCIENTIFIC" MEDICINE AROUND 1700.


THE ROLE OR ORAL SURGERY IN PREVENTIVE DENTISTRY.


PREVENTION AND PRESERVATION--THE CHALLENGE OF REMOVABLE PARTIAL DENTURE SERVICE.


PREVENTION OF SPACE LOSS.

PREVENTION OF SPACE LOSS.


MAXIMUM PREVENTION AND PRESERVATION: AN ACHIEVEMENT OF INTRAORAL MOUTH PROTECTORS.


THREE EFFICIENT TECHNICS OF APPLYING A TOPICAL FLUORIDE SOLUTION.


UTILIZATION OF SYSTEMIC FLUORIDES IN AREAS WITHOUT WATER FLUORIDATION.


DEVICE QUACKERY IN AMERICA.

DEVICE QUACKERY IN AMERICA.


UTILIZATION OF DIETARY COUNSELING IN A PRIVATE OFFICE.


THE FIELDING H. GARRISON LECTURE. WOMEN AND MEDICINE IN ANTE-BELLUM AMERICA.


ROMANTIC HYGEIA: J J VIREY--1775-1846, PHARMACIST AND PHILOSOPHER OF NATURE.


SURGICAL MANAGEMENT OF DIVERTICULITIS.

SURGICAL MANAGEMENT OF DIVERTICULITIS.


PALLIATIVE THERAPY FOR THE INOPERABLE PATIENT WITH CANCER OF THE RECTUM AND COLON.


ETIOLOGIC ASPECTS OF HEMORRHOIDAL DISEASE.


SKIN ANTIGEN TESTS AND THE FLUORESCENT ANTIBODY TECHNIQUE IN THE DIAGNOSIS OF SCHISTOSOMIASIS.


INTESTINAL OBSTRUCTION DUE TO ROUNDWORMS.


ACCURACY OF ROENTGENOLOGIC EXAMINATION IN DETECTING CARCINOMA OF THE COLON.


OBSERVATIONS ON A RAPID ENZYME-STRIP METHOD FOR ESTIMATING BLOOD GLUCOSE.


MALE CIRCUMCISION AMONG THE PEOPLES OF EAST AFRICA AND THE INCIDENCE OF GENITAL CANCER.


STEROID FRACTIONS FROM INCUBATED NORMAL AND REGENERATED ADRENAL GLANDS OF MALE AND FEMALE RATS.


EFFECT OF HYPOTHALAMIC AND MESENCEPHALIC STEROID IMPLANTATIONS ON ACTH FEEDBACK MECHANISMS.


MALIGNANT DEGENERATION IN ULCERATIVE COLITIS: A CASE REPORT.


ENDOGENOUS HISTAMINE IN MALE ORGANS OF REPRODUCTION.


INFLUENCE OF TWO NONSTEROIDAL ANTIESTROGENS ON VAGINAL OPENING AND PMS-INDUCED OVULATION IN RATS.


A UTERINE GROWTH-PROMOTING SUBSTANCE FROM HUMAN AND BOVINE UTERINE MUSCLE.


HORMONAL EFFECTS ON PHOSPHORYLASE ACTIVITY AND GLYCOGEN LEVELS IN THE RAT DUCTUS DEFERENS.


RELATIONSHIPS OF GROWTH HORMONE, STEROIDS AND RELAXIN IN THE TRANSFORMATION OF PUBIC JOINT CARTILAGE TO LIGAMENT IN HYPOPHYSECTOMIZED MICE.


INGUINAL HERNIA SIMULATING CARCINOMA OF THE COLON ON ROENTGENOLOGIC EXAMINATION AFTER BARIUM ENEMA.


MICRO-ANGIOGRAPHIC PATTERNS OF CHRONIC ULCERATIVE COLITIS.


INHIBITION OF NURSING-INDUCED AND STRESS-INDUCED FALL IN PITUITARY PROLACTIN CONCENTRATION IN LACTATING RATS BY INJECTION OF ACID EXTRACTS OF BOVINE HYPOTHALAMUS.


EFFECT OF SPECIES DIFFERENCES OF MICE ON THE BIO-ASSAY OF THYROTROPIN.


EFFECT OF CEREBRAL ABLATION ON A CIRCADIAN PITUITARY ADRENOCORTICOTROPIC RHYTHM IN C MICE.


AMEBOMA OF THE COLON.

AMEBOMA OF THE COLON.


BEHAVIOR OF HEPATIC GLUCONEOGENIC ENZYMES, RNA METABOLISM AND AMINO ACID LEVEL IN RATS CARRYING TRANSPLANTABLE ACTH-SECRETING PITUITARY TUMORS.


DECREASE IN THE CONCENTRATIONS OF KETONE BODIES AND FREE FATTY ACIDS IN RAT BLOOD IN RESPONSE TO A GLUCOSE LOAD: ITS POSSIBLE RELATION TO ENDOGENOUS INSULIN ACTIVITY.


131-I-LABELED BOVINE THYROTROPIN: PREPARATION THROUGH A NEW MICRO TECHNIQUE OF IODINE DISTILLATION AND STUDIES OF ADSORPTION TO GLASS AND POLYETHYLENE.


EFFECT OF STEROIDS ON GROWTH OF MOUSE FIBROBLASTS IN VITRO.


REVIEW OF LITERATURE ON DISEASES OF THE COLON AND RECTUM.


LOCAL TREATMENT OF CARCINOMA OF THE RECTUM.


RAT GROWTH HORMONE: IMMUNOFLUORESCENT AND RADIOIMMUNOLOGIC STUDIES.


RELATION BETWEEN THE BILIARY EXCRETION OF THYROXINE AND ITS BINDING BY THE SERUM PROTEINS IN MONKEYS.


ADRENAL STEROIDOGENIC EFFECT OF ADENOSINE 3',5'-MONOPHOSPHATE AND ITS DERIVATIVES IN VIVO.


THYROIDAL IODIDE TRANSPORT. VII. ACUTE STIMULATION OF THYROIDAL IODIDE CONCENTRATING ABILITY BY CYSTAMINE AND CYSTEAMINE.


STUDIES ON THE TIME OF LUTEINIZING HORMONE RELEASE IN GONADOTROPHIN-TREATED IMMATURE RATS.


TOTAL PANCREATECTOMY IN LIZARDS. EFFECTS OF SEVERAL HORMONES.


SIALIC ACID CONCENTRATIONS IN THE PITUITARY GLANDS OF NORMAL AND CASTRATED RATS.


GLUCOSE-6-PHOSPHATE DEHYDROGENASE ACTIVITY IN THE SUBCOMMISSURAL ORGAN OF RATS. A HISTOCHEMICAL STUDY.


INHIBITION OF VASOPRESSIN ANTIDIURESIS BY EXTRACTS OF PITUITARIES FROM RATS WITH HEREDITARY HYPOTHALAMIC DIABETES INSIPIDUS AND BY OXYTOCIN.


STEROID BIOSYNTHESIS IN VITRO BY FEMINIZING TESTES.


PARTIAL HYDROLYSIS OF BOVINE PARATHYROID HORMONE BY DILUTE ACID AND PROTEOLYTIC ENZYMES: EFFECTS ON IMMUNOLOGICAL AND BIOLOGICAL ACTIVITIES.


ULTRASTRUCTURE OF NEUROGLIA.

ULTRASTRUCTURE OF NEUROGLIA.


THE BLOOD FORMING TISSUES AND BLOOD OF THE NEWBORN OPOSSUM (DIDELPHYS VIRGINIANA). I. NORMAL DEVELOPMENT THROUGH ABOUT THE ONE HUNDREDTH DAY OF LIFE.


LACTOSE TOLERANCE IN RELATION TO INTESTINAL LACTASE ACTIVITY.


PANCREATIC VOLUME AND BICARBONATE OUTPUT WITH  AUGMENTED DOSES OF SECRETIN.


ANASTOMOTIC ULCER: SIGNIFICANCE OF THE AUGMENTED HISTAMINE TEST.


BLOOD GROUPS AND ULCERATIVE COLITIS.

BLOOD GROUPS AND ULCERATIVE COLITIS.


FACTORS INFLUENCING THE ABSORPTION. OF A MEDIUM CHAIN TRIGLYCERIDE. I.


RECOVERY OF GASTRIC MUCOSAL STRUCTURE AND FUNCTION IN PERNICIOUS ANEMIA DURING PREDNISOLONE THERAPY.


DIVERTICULITIS OF THE COLON IN A YOUNG MAN WITH  MARFAN'S  SYNDROME ASSOCIATED WITH CARCINOMA OF THE THYROID GLAND AND NEUROFIBROMAS OF THE TONGUE AND LIPS.


IN MEMORIAM; MARTIN EMIL REHFUSS, 1887-1964.


EXPERIENCES WITH THE ISOLATION OF DENGUE VIRUS TYPES 1, 2 AND 4 FROM HUMAN BLOOD.


COMPARATIVE AGGLUTINABILITY OF ERYTHROCYTES OF DIFFERENT SPECIES OF ANIMALS WITH ARBOVIRUSES.


A NEW ANTI-TUBERCULAR ANTIBIOTIC: ISOLATION CHARACTERIZATION AND IN VIVO EVALUATION.


ANTENATAL DETERMINATION OF FOETAL SEX.

ANTENATAL DETERMINATION OF FOETAL SEX.


ABO BLOOD GROUPS IN VITILIGO.

ABO BLOOD GROUPS IN VITILIGO.


THE EFFECT OF CALCIUM AND ASCORBIC ACID ON HEALING OF FRACTURES IN THYROXINE TREATED ANIMALS.


EFFECT OF ANGIOTENSIN ON CARDIAC ACCELERATOR CENTRE.


ESTIMATION OF RNA IN ANIMAL TISSUES.

ESTIMATION OF RNA IN ANIMAL TISSUES.


NUTRITIVE VALUE OF SOME INDIAN FOODSTUFFS.


TOXIC FACTORS IN LATHYRUS SATIVUS.

TOXIC FACTORS IN LATHYRUS SATIVUS.


HISTOCHEMICAL STUDIES IN HISTOLOGICALLY  NORMAL ENDOMETRIUM.


PRENATAL SEX PREDICTION OF THE FETUS.

PRENATAL SEX PREDICTION OF THE FETUS.


POLYCYSTIC DISEASE OF THE LIVER: A CASE REPORT.


A COMPARISON OF SOME COMMONLY USED  ORAL ANALGESICS ON HUMAN VOLUNTEERS.


SPINAL EPIDURAL ABSCESS: CASE REPORTS WITH REVIEW OF LITERATURE.


RESPONSES FROM THE NERVOUS SYSTEM ON TWO OPPOSITE COMMANDS. A REVIEW.


BENEFICIAL EFFECT OF ADANSONIA DIGITATA (GORAKHA CHINCH) IN BRONCHIAL ASTHMA AND ALLERGIC (SKIN DISORDERS).


SPINAL ANAESTHESIA.

SPINAL ANAESTHESIA.


FAMILY PLANNING--THE STUDY OF THE PROBLEM.


BRUCELLOSIS IN PUNJAB AND OTHER STATES OF INDIA.


THE ROLE OF THE GENERAL PRACTITIONER IN COMMUNITY PSYCHIATRY.


THE FOLLOW-UP HISTORY OF PULMONARY TUBERCULOSIS.


CARDIAC IRREGULARITIES WITH NORMAL PULSE.


VITAL CLUES IN THE DIETARY PROGRAMME FOR HEART PATIENTS.


CHEMICAL PNEUMONITIS--A COMPLICATION OF KEROSENE OIL POISONING.


CHILD SACRIFICE (REPORT OF A CASE).

CHILD SACRIFICE (REPORT OF A CASE).


A CASE OF TYPHUS FEVER.

A CASE OF TYPHUS FEVER.


CHROMATIN-POSITIVE KLINEFELTER'S SYNDROME  (A CASE REPORT).


TEMPORAL ARTERITIS (A CASE REPORT).

TEMPORAL ARTERITIS (A CASE REPORT).


THERAPY OF PSYCHOSOMATIC DISORDERS.

THERAPY OF PSYCHOSOMATIC DISORDERS.


THE STEADY-STATE SYSTEM IN IMMUNE HEMOLYSIS DESCRIPTION AND ANALYSIS; APPLICATION TO THE ENUMERATION OF SAC'4.


THE PREPARATION AND PROPERTIES OF A HAPTEN-CELLULOSE ANTIBODY ADSORBENT.


HYBRID MOLECULES OF RABBIT GAMMA-GLOBULIN FORMED BY RECOMBINATION OF HALF-MOLECULES OF GAMMA-GLOBULINS DIFFERING IN GENOTYPE AT TWO LOCI.


EQUINE ANTIHAPTEN ANTIBODY II. THE GAMMA-G(7S-GAMMA) COMPONENTS AND THEIR SPECIFIC INTERACTION.


ISOLATION AND STUDY OF THE FUNCTION OF HUMAN GAMMA-2-GLOBULIN GLYCOPEPTIDE.


SEPARATION OF SKIN-SENSITIZING AND COMPLEMENT-FIXING ANTIBODIES FROM GUINEA PIG ANTI-BOVINE INSULIN SERA.


INFRARED SPECTRA OF COMPLEXES OF L-CYSTEINE AND RELATED COMPOUNDS WITH ZINC (II), CADMIUM (II), MERCURY (II), AND LEAD (II).


A SYNTHESIS OF PYRIMIDO(4,5-E)-AS-TRIAZINES (6-AZAPTERIDINES).


STUDIES IN PURINE CHEMISTRY. 13. SYNTHESIS OF THE 5-AZA ANALOGS OF ADENINE AND HYPOXANTHINE.


SYNTHESIS OF PYRROLO(2,3-D)PYRIMIDINES. THE AGLYCONE OF TOYOCAMYCIN.


GRAMICIDIN A. V. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN A.


GRAMICIDIN A. VI. THE SYNTHESIS OF VALINE- AND ISOLEUCINE-GRAMICIDIN A.


GRAMICIDIN. VII. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN B.


THE TAUTOMERIC FORM OF HELICAL POLYRIBOCYTIDYLIC ACID.


THE STEREOSPECIFIC SYNTHESIS OF THREO-GAMMA-HYDROXYHOMO-L-ARGININE FROM LATHYRUS SPECIES.


STUDIES ON PEPTIDES. II. SYNTHESIS AND PHYSIOLOGICAL PROPERTIES OF D-HISTIDYL-D-PHENYLALANYL-D-ARGINYL-D-TRYPTOPHYLGLYCINE, AN OPTICAL ANTIPODE OF AN ACTIVE FRAGMENT OF ALPHA-MELANOCYTE-STIMULATING HORMONE.


STRUCTURE OF PIERCIDIN A.

STRUCTURE OF PIERCIDIN A.


CASEIN MICELLES. FORMATION AND STRUCTURE. I.


CASEIN MICELLES. FORMATION AND STRUCTURE. II.


DISMUTATION REACTIONS OF NUCLEOSIDE POLYPHOSPHATES. I. GENERAL FEATURES OF THE REACTION.


A CORRELATION BETWEEN THE BIOLOGICAL ACTIVITY OF ALKYLTRIMETHYLAMMONIUM IONS AND THEIR MODE OF INTERACTION WITH ACETYLCHOLINESTERASE.


OXIDATIVE TRANSFORMATIONS OF INDOLE ALKALOIDS. 3. PSEUDOINDOXYLS FROM YOHIMBINOID ALKALOIDS AND THEIR CONVERSION TO "INVERT" ALKALOIDS.


INTERACTION OF THE RADICAL ION OF CHLORPROMAZINE WITH DEOXYRIBONUCLEIC ACID.


ON THE DEFINITION OF "ATHEROSCLEROSIS" IN CLINICAL STUDIES.


THE PREVENTION OF RABBIT ATHEROSCLEROSIS BY SOYA BEAN MEAL.


SERUM LIPID CHANGES FOLLOWING MYOCARDIAL INFARCTION.


THE INFLUENCE OF THE VELOCITY GRADIENT ON IN VITRO BLOOD COAGULATION AND ARTIFICIAL THROMBOSIS.


THE SIGNIFICANCE OF FORCED WEANING OF THE YOUNG IN THE PATHOGENESIS OF POSTGESTATIONAL AORTIC LESIONS IN RATS.


THE EFFECT OF PROLONGED TREATMENT WITH HEPARIN ON LIPOPROTEIN-LIPASE ACTIVITY IN THE BLOOD.


HISTOGENESIS OF MELANOCYTES.

HISTOGENESIS OF MELANOCYTES.


ADRENOCORTICAL FUNCTION IN ARTERIOSCLEROTIC FEMALE BREEDER RATS.


KERATINOLYTIC ACTIVITY OF MICROSPORUM CANIS AND  MICROSPORUM GYPSEUM.


THE DISTRIBUTION OF EPIDERMAL PHOSPHOLIPIDS AND THEIR RELATION TO THE ALKALINE PHOSPHATASE ACTIVITY OF THE GRANULAR LAYER.


THE AMINO ACID COMPOSITION OF PROTEIN FRACTIONS FROM NORMAL AND ABNORMAL EPIDERMIS.


SCLEREMA NEONATORUM.

SCLEREMA NEONATORUM.


LIPIDS OF VERNIX CASEOSA.

LIPIDS OF VERNIX CASEOSA.


THIN-LAYER CHROMATOGRAPHY OF THE PIGMENTS ISOLATED FROM SOME TRICHOPHYTON SPECIES.


POSSIBLE PINOCYTOSIS IN EPIDERMIS.

POSSIBLE PINOCYTOSIS IN EPIDERMIS.


FATTY ACIDS OF HAIR LIPIDS OF GERM FREE AND GERM EXPOSED RATS.


CHEMICAL STRUCTURE AND SKIN PENETRATING CAPACITY OF A SHORT SERIES OF ORGANIC PHOSPHATES AND PHOSPHORIC ACID.


TUMORS OF THE SKIN. IV. DOUBLE-BLIND STUDY ON EFFECTS OF LOCAL ADMINISTRATION OF ANTI-TUMOR AGENTS IN BASAL CELL CARCINOMA.


STRENGTH OF FINGERNAILS.

STRENGTH OF FINGERNAILS.


THE USE OF SYSTEMIC TETRACYCLINE AND ULTRAVIOLET IN PSORIASIS: A PRELIMINARY REPORT.


KERATIN IN MONILETHRIX.

KERATIN IN MONILETHRIX.


THE EFFECT OF ATROMID-S ON THE FIBRINOLYTIC ENZYME SYSTEM.


CARDIAC EMERGENCIES.

CARDIAC EMERGENCIES.


EVALUATION OF THE DUHAMEL TYPE OPERATION FOR HIRSCHSPRUNG'S DISEASE.


SO-CALLED ALVEOLAR-CELL CARCINOMA OF THE LUNG; REPORT OF A CASE.


THE PSYCHIATRY OF PRESIDENTIAL ASSASSINATION: 3. THE ROOSEVELTS.


COEXISTENT SARCOIDOSIS AND GOUT.

COEXISTENT SARCOIDOSIS AND GOUT.


THE USE OF LARGE DOSES OF ANGIOTENSIN IN ACUTE MYOCARDIAL INFARCTION WITH SHOCK.


BASIC NEUROPHYSIOLOGIC ASPECTS OF EPILEPSY.


ENVIRONMENTAL TERATOGENS AND BIRTH DEFECTS.


MALIGNANT MESENCHYMOMA OF THE HEART.

MALIGNANT MESENCHYMOMA OF THE HEART.


PHILIP SHOWALTER HENCH, M.D.

PHILIP SHOWALTER HENCH, M.D.


MUCOUS MEMBRANE PEMPHIGUS.

MUCOUS MEMBRANE PEMPHIGUS.


SOLITARY PLASMACYTOMA OF THE UPPER AIR PASSAGES.


MONOSTOTIC FIBROUS DYSPLASIA AFFECTING THE SKULL AND FACIAL BONES.


INDUSTRIAL HAZARDS ON THE NOSE.

INDUSTRIAL HAZARDS ON THE NOSE.


CLINICAL RECORDS. TUBERCULOSIS OF TONGUE ("PRIMARY TYPE"); A CASE REPORT.


THE "AVASCULAR" GLOMUS JUGULARE TUMOUR.

THE "AVASCULAR" GLOMUS JUGULARE TUMOUR.


THE RELATION OF THE O-ANTISTREPTOLYSIN TITRE (ASO) BETWEEN THE TONSILS AND THE BLOOD SERUM IN CHRONIC TONSILLITIS.


DYSONTOGENETIC DERMOID OF THE EUSTACHIAN TUBE.


LATERAL SINUS THROMBOSIS FOLLOWING FURUNCLE OF EXTERNAL AUDITORY CANAL.


A CASE OF KLIPPEL-FEIL SYNDROME WITH CONGENITAL SHORT PALATE.


LOCALIZATION ON HEPATIC RIBOSOMES OF PROTEIN NEWLY SYNTHESIZED IN VIVO.


MOLECULAR WEIGHTS OF HEPATIC RIBOSOMES AND THEIR SUBUNITS.


STUDY OF THE FOLDING OF THE DAT COPOLYMER BY KINETIC MEASUREMENTS OF MELTING.


ISOLATION AND PROPERTIES OF DOUBLE-STRANDED VIRAL RNA FROM VIRUS-INFECTED PLANTS.


NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.


HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA COLI V . THE ROLE OF METHIONINE IN THE PRODUCTION OF HOST SPECIFICITY.


ENZYMIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XX. ELECTRON MICROSCOPY OF PRODUCTS PRIMED BY NATIVE TEMPLATES.


REPLICATION OF RNA VIRUSES.  II. THE RNA PRODUCT OF A REACTION  CATALYZED BY A VIRAL RNA-DEPENDENT RNA POLYMERASE.


REPLICATION OF RNA VIRUSES I. CHARACTERIZATION OF A VIRAL RNA-DEPENDENT RNA POLYMERASE.


ELECTRON MICROSCOPE STUDIES OF BACTERIAL FLAGELLA.


ON THE ORIGIN OF CRYSTALLIZABLE RNA FROM YEAST.


CHEMICAL MECHANISM OF SONIC, ACID, ALKALINE AND ENZYMIC  DEGRADATION OF DNA.


HETEROGENEITY IN THE NUCLEOTIDE SEQUENCE NEAR THE AMINO ACID-ACCEPTING TERMINAL OF TRANSFER RNA.


ROLE OF THE GENETIC MESSAGE IN POLYRIBOSOME FUNCTION.


SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.


STRUCTURE OF VIRUSES OF THE PAPILLOMA-POLYOMA TYPE. I. HUMAN WART  VIRUS.


STRUCTURE OF VIRUSES OF THE PAPILLOMA-POLYOMA TYPE. II. COMMENTS ON OTHER WORK.


ELECTRON MICROSCOPIC STUDIES ON THE SERUM ALBUMIN MOLECULES.


X-RAY STUDY OF SPERMIDINE TRIHYDOCHLORIDE.


X-RAY STUDY OF SPERMINE TETRAHYDROCHLORIDE.


EPIDEMIOLOGICAL APPROACH TO MATERNITY HEALTH NEEDS.


ENTRANCE OF NEWLY FORMED MESSENGER RNA AND RIBOSOMES INTO HELA CELL CYTOPLASM.


TOTAL REHABILITATION OF THE CLEFT PALATE PATIENT.


COUGH.

COUGH.


RESEARCH PROBLEMS IN ORAL SURGERY.

RESEARCH PROBLEMS IN ORAL SURGERY.


TRAINING FOR RESEARCH.

TRAINING FOR RESEARCH.


CRITIQUE OF RESEARCH PROPOSALS AND THEIR FINDINGS.


FUNDING OF RESEARCH.

FUNDING OF RESEARCH.


SELECTION OF A RESEARCH PROJECT.

SELECTION OF A RESEARCH PROJECT.


BIOSTATISTICS IN CLINICAL RESEARCH.

BIOSTATISTICS IN CLINICAL RESEARCH.


ROLE OF BASIC SCIENCE IN THE INVESTIGATION OF CLINICAL PROBLEMS.


REPORTING RESEARCH RESULTS.

REPORTING RESEARCH RESULTS.


CLINICAL RESEARCH: DESIGN AND METHODOLOGY.


THE LITERATURE--ITS ROLE IN RESEARCH.

THE LITERATURE--ITS ROLE IN RESEARCH.


REFLECTIONS ON RESEARCH, TEACHING AND PRACTICE.


A CONVENIENT SYNTHESIS OF 3-BETA-HYDROXYANDROST-4-EN-17 ONE.


CONFORMATIONAL ANALYSIS. XXXIX. THE CONFORMATIONS OF RING A IN BROMO DERIVATIVES OF CHOLESTAN-3-ONE AND RELATED COMPOUNDS.


NEW APPROACHES TO THE SYNTHESIS OF 5H-PYRROLO(3,2-D)PYRIMIDINES.


NUCLEOTIDES. I. THE REACTION OF CYCLOURIDINES WITH BENZYL HYDROGEN PHOSPHORIC BENZOIC ANHYDRIDE.


SYNTHESIS OF PHENISTIDINE AND DERIVATIVES.


THE ANOMERIC 9-(2-AMINO-2-DEOXY-D-GLUCOPYRANOSYL)ADENINES.


NUCLEAR MAGNETIC RESONANCE SPECTRA AND STEREOCHEMISTRY OF THE ANTIBACTERIAL PRINCIPLE FROM HAEMATOXYLON BRAZILETTO.


ON THE ISOLATION OF THE ALLERGENICALLY ACTIVE COMPONENTS OF THE TOXIC PRINCIPLE OF POISON IVY.


PERSONALITY PROFILES IN INDUSTRIAL AND PREINDUSTRIAL CULTURES: A TAT STUDY.


BEHAVIOR IN CERTAIN ZERO-SUM, TWO-PERSON GAMES.


VOLATILES FROM ORANGES. 3. THE STRUCTURE OF SINENSAL.


PERCEPTUAL CORRELATES OF PREJUDICE: A STEREOSCOPIC-CONSTANCY EXPERIMENT.


ATTITUDES TOWARD BLINDNESS AND OTHER PHYSICAL HANDICAPS.


THE EFFECTS OF VERBAL REINFORCEMENT ON CONFORMITY AND DEVIANT BEHAVIOR.


THE RELATION OF ORDER OF RECALL TO VARIOUS MEASURES OF AFFECT.


ATTITUDES TOWARD THE INTEROFFICE MEMO AS A COMMUNICATION DEVICE.


THE QUEST FOR SUBJECTIVE CERTAINTY.

THE QUEST FOR SUBJECTIVE CERTAINTY.


COGNITIVE COMPLEXITY AND THE INTEGRATION OF CONFLICTING INFORMATION IN WRITTEN IMPRESSIONS.


ANCHORAGE AND ORDERING EFFECTS OF INFORMATION ON PERSONALITY IMPRESSION.


CRITICAL THINKING AND OPENMINDEDNESS IN PUPILS FROM PUBLIC AND CATHOLIC SECONDARY SCHOOLS.


THEORIES OF PANIC BEHAVIOR: A REVIEW.

THEORIES OF PANIC BEHAVIOR: A REVIEW.


CHANGE IN RELIGIOUS ATTITUDES DURING FOUR YEARS OF COLLEGE.


ACHIEVEMENT MOTIVATION, AFFILIATION MOTIVATION, AND TASK DIFFICULTY AS DETERMINANTS OF SOCIAL CONFORMITY.


BEHAVIORAL FACTORS IN DISASTER SITUATIONS.


DIFFERENCES IN GENERAL PERSUASIBILITY TO PEER GROUP PRESSURE BETWEEN CATHOLIC HIGH SCHOOL AND PUBLIC HIGH SCHOOL STUDENTS.


MOTIVATIONAL AND PERCEPTUAL EFFECTS IN ORIENTATION TOWARD A NEWCOMER.


THE PHYSICIAN AND THE TERMINAL PATIENT.

THE PHYSICIAN AND THE TERMINAL PATIENT.


SEX DIFFERENCES AND SUSCEPTIBILITY TO INTERPERSONAL PERSUASION.


THE RENAL AND SYSTEMIC EFFECTS OF HYDROXYETHYL STARCH SOLUTION INFUSIONS.


RELATIONSHIP BETWEEN RATED LEADERS AND THE TRAITS ASSIGNED TO THESE LEADERS.


RENAL HEMODYNAMICS AND FUNCTION IN EXPERIMENTAL HEMORRHAGIC HYPOTENSION: EFFECTS OF OSMOTIC DIURESIS.


RENAL FUNCTION AFTER LEFT RENAL VEIN LIGATION.


RENAL MILK-OF-CALCIUM STONE.

RENAL MILK-OF-CALCIUM STONE.


AMYLOIDOSIS IN THE PARAPLEGIC; INCIDENCE AND SIGNIFICANCE.


MANAGEMENT OF UPPER URINARY TRACT COMPLICATIONS IN MULTIPLE SCLEROSIS BY MEANS OF URINARY DIVERSION TO AN ILEAL CONDUIT.


REVERSIBILITY OF RENAL FUNCTIONAL IMPAIRMENT AFTER PROSTATIC OBSTRUCTION.


INFECTED SOLITARY RENAL CYST.

INFECTED SOLITARY RENAL CYST.


UNINTUBATED BOARI'S URETEROCYSTOPLASTY.

UNINTUBATED BOARI'S URETEROCYSTOPLASTY.


BOARI'S OPERATION FOR THE TREATMENT OF MEGAURETER.


PRIMARY MUCUS-PRODUCING ADENOCARCINOMA OF THE RENAL PELVIS: REPORT OF A CASE.


ECTOPIC URETERAL OPENING INTO SEMINAL VESICLE: A REPORT OF FOUR CASES.


URETERAL PHYSIOLOGY AND EXSTROPHY OF THE BLADDER.


SOME PROBLEMS IN SURGICAL MANAGEMENT OF RUPTURED URETHRA IN FRACTURE OF PELVIS.


REGENERATION OF TRANSITIONAL EPITHELIUM OF THE HUMAN BLADDER AFTER TOTAL SURGICAL EXCISION FOR RECURRENT, MULTIPLE BLADDER CANCER: APPARENT TUMOR INHIBITION.


MALIGNANT MELANOMA OF THE PENIS.

MALIGNANT MELANOMA OF THE PENIS.


CLINICAL ADENOCARCINOMA OF THE PROSTATE IN PATIENTS UNDER 50 YEARS OF AGE.


MELANOMA OF THE GENITOURINARY TRACT.

MELANOMA OF THE GENITOURINARY TRACT.


PREVENTION OF SEVERE THIGH-ADDUCTION SPASMS DURING TRANSURETHRAL RESECTION.


UROLOGIC ASPECTS OF BACTEREMIA AND SEPTICEMIC SHOCK.


TECHNICAL CONSIDERATIONS IN RENAL ARTERIOGRAPHY: SOME MODIFICATIONS OF RETROGRADE FEMORAL CATHETERIZATION TECHNIQUE.


THE TROUSER LEG APRON.

THE TROUSER LEG APRON.


THE VALSALVA MANEUVER IN RENAL ANGIOGRAPHY.


ROENTGENOGRAPHIC FINDINGS IN GARDNER'S SYNDROME.


TREATMENT OF PRIMARY DYSMENORRHEA: A DOUBLE-BLIND STUDY.


PRECIPITATION OF ACUTE INTERMITTENT PORPHYRIA BY GRISEOFULVIN THERAPY.


PROGRESS IN INSURANCE CLAIM FORMS.

PROGRESS IN INSURANCE CLAIM FORMS.


GENETIC CONTROL OF THE QUANTITATIVE ACTIVITY OF A  SERUM ENZYME IN MAN.


STAPHYLOCOCCUS OF A NEWLY RECOGNIZED BACTERIOPHAGE TYPE: REPORT OF A HOSPITAL OUTBREAK.


JUVENILE OSTEOCHONDROSIS OF THE HIP: CRITICAL EVALUATION OF  PATHOGENESIS AND TREATMENT.


VENTRICULAR FIBRILLATION DURING SELECTIVE ANGIOCARDIOGRAPHY.


IATROGENIC HEART DESEASE.

IATROGENIC HEART DESEASE.


"VASCULAR RASPBERRY" FORMATIONS OF THE STOMACH AND PEPTIC ULCER.


LATE RECOGNITION OF BRONCHOGENIC CARCINOMA IN THE THORACIC INLET.


SELDOM-ENCOUNTERED AGENTS OF BACTERIAL MENINGITIS.


CLINICAL STUDIES WITH CLOXACILLIN: A NEW ANTIBIOTIC.


PERCUTANEOUS POLYETHYLENE TUBE TRACHEOSTOMY.


DRUG PROBLEMS AND THE PHILADELPHIA PLAN.


CYTOGENETICS IN CLINICAL ENDOCRINOLOGY.

CYTOGENETICS IN CLINICAL ENDOCRINOLOGY.


PHOTOSENSITIVITY INDUCED BY DRUGS.

PHOTOSENSITIVITY INDUCED BY DRUGS.


IATROGENIC ASPECTS OF DIGITALIS INTOXICATION.


ANAPHYLACTIC REACTIONS TO TETRACYCLINE.

ANAPHYLACTIC REACTIONS TO TETRACYCLINE.


A DISTINCTIVE EXANTHEM.

A DISTINCTIVE EXANTHEM.


CHOLERA IMMUNIZATION.

CHOLERA IMMUNIZATION.


NEW HOSPITAL STAPHYLOCOCCI.

NEW HOSPITAL STAPHYLOCOCCI.


HERPES SIMPLEX SKIN LESIONS SIMULATING SMALLPOX.


FINE STRUCTURE AND DEVELOPMENT OF AUER BODIES.


ANAPHYLACTIC REACTION TO TETRACYCLINE IN A PENICILLIN-ALLERGIC PATIENT: IMMUNOLOGIC STUDIES.


OCCIPITALISATION OF THE ATLAS (CASE REPORT).


STUDIES ON THE METABOLISM OF THE HOSTS OF PARAGONIMUS WESTERMANI (KERBERT, 1878). II. PAPER CHROMATOGRAPHY OF SOME METABOLITES IN THE BLOOD OF ERIOCHEIR JAPONICUS (DE HAAN).


THE PURITY OF COMMERCIAL CHOLESTEROL AS THE STANDARD FOR THE DETERMINATION OF CHOLESTEROL.


A CASE OF HUMAN EMBRYO WITH CLEFT LIP.

A CASE OF HUMAN EMBRYO WITH CLEFT LIP.


STUDY ON THE ANTIGENICITY OF THE HUMAN NONHEMOGLOBIN PROTEINS.


JOHN REDMAN (1722-1808)--CHAMPION OF INOCULATION.


HYPERBILIRUBINEMIA DUE TO HYPOXIA.

HYPERBILIRUBINEMIA DUE TO HYPOXIA.


UROLOGICAL OBSERVATION IN TRAUMATIC PARAPLEGIA WITH REFERENCE TO PYELOGRAMS AND CYSTOGRAMS.


MEDICAL PHOTOGRAPHY IN THE UNITED KINGDOM.


MEDICAL PHOTOGRAPHY IN FRANCE.

MEDICAL PHOTOGRAPHY IN FRANCE.


MEDICAL PHOTOGRAPHY IN HOLLAND.

MEDICAL PHOTOGRAPHY IN HOLLAND.


MEDICAL PHOTOGRAPHY IN SWEDEN.

MEDICAL PHOTOGRAPHY IN SWEDEN.


A STROBOSCOPIC TECHNIQUE FOR ELECTRON MICROGRAPHS.


SYMPOSIUM I. ORGANIZATION OF THE ILLUSTRATION DEPARTMENT.


INDIRECT KINE-LARYNGOSCOPY.

INDIRECT KINE-LARYNGOSCOPY.


THE ENDO-MICROSCOPE.

THE ENDO-MICROSCOPE.


LASERS.

LASERS.


ICONOGRAPHIC COLLECTIONS OF THE COLLEGE DE MEDECINE DES HOPITAUX DE PARIS.


MICROTOPOGRAPHY OF THE SKIN.

MICROTOPOGRAPHY OF THE SKIN.


SYMPOSIUM II. THE FUNCTION OF THE ILLUSTRATION DEPARTMENT--THE DISSEMINATION OF MEDICAL INFORMATION.


IMPORTANCE OF RETINOGRAPHY IN A PSYCHIATRIC HOSPITAL.


"PHOTOTHECA CHURURGICA" AN AUDIOVISUAL SERIES FOR TEACHING GENERAL SURGERY.


SYMPOSIUM 3. THE LECTURE THEATRE.

SYMPOSIUM 3. THE LECTURE THEATRE.


METHODS FOR MEDICAL PHOTOGRAPHY IN BLACK-AND-WHITE AND COLOUR.


STUDIES OF MEDICAL STUDENT ATTITUDES TOWARD MENTAL ILLNESS.


IN SEARCH OF THE MISSING LINK BETWEEN SOCIAL CHANGE AND SOCIAL WORK: A CANADIAN EXPERIENCE IN ACTION FOR MENTAL HEALTH.


RECREATION, ENERGY LEVEL AND WORK OF SCHIZOPHRENICS.


COMMUNITY MENTAL HEALTH EDUCATION WITH POLICE.


MENTAL HEALTH EDUCATION AT AN ARMY BASIC TRAINING CENTER--AN OPERATIONAL MODEL.


PAID EMPLOYMENT AS A REHABILITATIVE TECHNIQUE IN A STATE MENTAL HOSPITAL: A DEMONSTRATION.


RUNNING A BRITISH MENTAL HOSPITAL.

RUNNING A BRITISH MENTAL HOSPITAL.


PATTERNS OF SCHIZOPHRENIC ADMISSIONS TO OHIO PUBLIC MENTAL HOSPITALS.


A GUIDE TOWARD ESTABLISHING PATIENT GOVERNMENT.


EXPANDING COMPREHENSIVENESS OF PSYCHIATRIC REHABILITATION.


COMBATING POST-HOSPITAL BENDS: PATTERNS OF SUCCESS AND FAILURE IN A PSYCHIATRIC HALFWAY HOUSE.


EMPLOYMENT AND MENTAL ILLNESS.

EMPLOYMENT AND MENTAL ILLNESS.


COMMUNITY CENTER RESOCIALIZATION OF FORMER PSYCHIATRIC PATIENTS.


THE DAY CENTER AS AN ALTERNATIVE TO THE PSYCHIATRIC WARD.


BEYOND PSYCHIATRIC DIAGNOSIS IN SOCIAL PLANNING.


COMMUNITY ACTION AND ALCOHOL REHABILITATION: A CASE STUDY OF FAILURE.


EFFECTS OF STIGMA ON RE-EMPLOYMENT OF EX-MENTAL PATIENTS.


PUPIL PERCEPTIONS OF PARENTAL ATTITUDES TOWARD SCHOOL.


EVIL SELF-IMAGE: A COMMON DENOMINATOR IN LEARNING PROBLEMS.


PROPHYLACTIC PORTACAVAL ANASTOMOSIS IN CIRRHOTIC PATIENTS WITH ESOPHAGEAL VARICES: A PROGRESS REPORT OF A CONTINUING STUDY.


FAMILIAL HYPERPROLINEMIA. REPORT OF A SECOND CASE, ASSOCIATED WITH CONGENITAL RENAL MALFORMATIONS, HEREDITARY HEMATURIA AND MILD MENTAL RETARDATION, WITH DEMONSTRATION OF AN ENZYME DEFECT.


SIGNIFICANCE OF 7S AND MACROGLOBULIN BRUCELLA AGGLUTININS IN HUMAN BRUCELLOSIS.


ARTHRITIS WITH SYNOVIAL IRON DEPOSITION IN A PATIENT WITH HEMOCHROMATOSIS.


HORMONES OF THE ANTERIOR PITUITARY BODY.


FREQUENCY OF PULMONARY THROMBOEMBOLISM IN MAN.


ANAPHYLACTIC DEATH AFTER ADMINISTRATION OF A TRIPHENYLMETHANE DYE TO DETERMINE BURN DEPTH.


CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL. CASE 27-1965.


THE GENIUS OF CLAUDE BERNARD.

THE GENIUS OF CLAUDE BERNARD.


COMMITTEE ON MATERNAL WELFARE: FATAL PANCREATITIS AT THIRTY-SIX WEEKS.


THE DANGERS OF X-RAYS TO THE PHYSIOTHERAPIST.


THE TREATMENT OF SMALLPOX VACCINATION ULCERS WITH ULTRA-VIOLET LIGHT.


A "COUGH BELT" TO PREVENT AND TREAT PULMONARY COMPLICATIONS IN ABDOMINAL AND THORACIC SURGERY AND IN CERTAIN MEDICAL DISEASES.


STARTING A PHYSIOTHERAPY DEPARTMENT IN THE NEW MANITOBA REHABILITATION  HOSPITAL, WINNIPEG.


EFFECT OF SCHOOL WATER FLUORIDATION ON DENTAL CARIES, ST. THOMAS, V.I.


CDC BECOMES SOLE NATIONAL REFERENCE CENTER FOR BACTERIOPHAGE TYPING OF STAPHYLOCOCCI.


EFFECTS OF MEDICAL "TRIAGE" IN HOSPITAL EMERGENCY SERVICE.


PILOT STUDY OF QUALITY AND STANDARDS IN FILLING SPECTACLE PRESCRIPTIONS.


SURVEY OF HOME-DELIVERED MEALS PROGRAMS.


SERVICES RECEIVED BY MARYLAND RESIDENTS IN FACILITIES DIRECTED BY A PSYCHIATRIST.


DETERIORATION OF THE BEDFAST PATIENT; CAUSES AND EFFECTS.


ORAL POLIOMYELITIS VACCINATION PROGRAM IN BERKS COUNTY, PENNSYLVANIA.


THE PSYCHIATRIC INDICATIONS FOR GROUP PSYCHOTHERAPY.


EFFECT OF PSYCHOTHERAPY FOR PSYCHOSOMATIC DISORDERS.


PROBLEMS IN PSYCHOSOMATIC DIAGNOSIS. 3. PHYSICAL EXAMINATIONS, LABORATORY PROCEDURES, AND PSYCHIATRIC CONSULTATIONS.


MANAGEMENT OF EMOTIONAL ILLNESSES IN GENERAL PRACTICE.


FIELD METHOD FOR RAPID COLLECTION OF IODINE 131 FROM MILK.


ACUTE DIARRHEAL DISEASES IN A ZUNI COMMUNITY.


TRIPARTITE PSYCHIATRY--IATROPSYCHOLOGY, IATROPHYSICS, AND IATROCHEMISTRY.


(DETERIORATION OF THE BEDFAST PATIENT; NURSING CARE.)


A MODEL FOR RESOLVING THE MIND-BODY PROBLEM.


OBESITY--SIN OR SAVIOR?

OBESITY--SIN OR SAVIOR?


USE OF MICRO TECHNIQUE FOR SERUM NEUTRALIZATION AND VIRUS IDENTIFICATION.


1963 EPIDEMIC OF POLIOMYELITIS IN BARBADOS, WEST INDIES.


PSYCHOSOMATIC DISORDERS IN PROSPECTIVE IMMIGRANTS TO CANADA: AN  EPIDEMIOLOGICAL STUDY.


A MULTIPLE APPROACH TO THE MANAGEMENT OF DEPRESSION-TENSION STATES.


CASE OF ADULT ENURESIS SUCCESSFULLY TREATED WITH AMITRIPTYLINE HYDROCHLORIDE.


PSYCHOSOMATIC GROUP THERAPY WITH PARENTS OF CHILDREN WITH INTRACTABLE ASTHMA. 3. SIBLING RIVALRY AND SIBLING SUPPORT.


A CURRENT BIBLIOGRAPHY ON ALLERGY AND APPLIED IMMUNOLOGY.


THE IMPURE PLACEBO, THE INELEGANT EXPERIMENT AND THE SEDUCTIVE EXPERT. II.


KINSHIP AND OCCUPATIONAL SUCCESSION.

KINSHIP AND OCCUPATIONAL SUCCESSION.


FACTORS RELATING TO AN ADOPTION DECISION BY THE MOTHERS OF ILLEGITIMATE INFANTS.


WORK AND NON-WORK IN THREE OCCUPATIONS.

WORK AND NON-WORK IN THREE OCCUPATIONS.


READING SKILLS AND THE CEREBRAL PALSIED--A COMPARATIVE STUDY.


PRACTICAL ASPECTS OF SPEECH THERAPY IN CEREBRAL PALSY.


ASSESSMENT OF HEARING AND SPEECH DISORDERS IN CEREBRAL PALSY.


METHODS OF TEACHING CHILDREN WITH COMMUNICATION DIFFICULTIES.


HOMECRAFT FOR THE HANDICAPPED.

HOMECRAFT FOR THE HANDICAPPED.


SENSORY AND PERCEPTUAL DIFFICULTIES IN THE BRAIN INJURED CHILD.


READING SKILLS AND THE CEREBRAL PALSIED.


INTELLIGENCE TESTING OF THE MULTIPLE HANDICAPPED CHILD WITH COMMUNICATION DIFFICULTIES.


SPEECH COMMUNICATION DIFFICULTIES IN THE BRAIN-INJURED CHILD.


MINIMAL CEREBRAL DYSFUNCTION.

MINIMAL CEREBRAL DYSFUNCTION.


THYROID SURGERY FOR BENIGN AND MALIGNANT DISEASE.


THE VALUE AND POTENTIAL OF TELEVISION IN RADIOLOGIC DIAGNOSIS.


SURGICAL MANAGEMENT OF PANCREATIC CYSTS.


THE OPERATION OF CHOICE FOR THE SURGICAL TREATMENT OF DUODENAL ULCER.


TUMORS OF THE NECK.

TUMORS OF THE NECK.


MODIFICATION OF THE ROUX-EN-Y PROCEDURE.


REPAIR OF BENIGN STRICTURES OF THE BILE DUCTS.


TECHNIQUE OF SHUNT PROCEDURES FOR PORTAL HYPERTENSION.


RADICAL HEAD AND NECK SURGERY IN IRRADIATED PATIENTS: COMPLICATIONS AND SAFEGUARDS.


HEPATIC ARTERY ANOMALIES OR DEFORMITIES MANAGED DURING INFUSION CHEMOTHERAPY OF LIVER CANCER.


CURRENT SURGICAL MANAGEMENT OF RECTAL PROCIDENTIA.


TOTAL COLECTOMY AND ILEOPROCTOSTOMY FOR POLYPOSIS.


USE OF THE RADIO-FREQUENCY ELECTRODE IN STEREOTACTIC SURGERY OF PARKINSON'S DISEASE.


SURGICAL MANAGEMENT OF DIVERTICULUM OF THE URINARY BLADDER.


ABDOMINAL ANEURYSM.

ABDOMINAL ANEURYSM.


SURGICAL TREATMENT FOR DIVERTICULITIS.

SURGICAL TREATMENT FOR DIVERTICULITIS.


SURGICAL ABLATION OF THE PITUITARY GLAND.


TECHNIQUES OF FEMORAL POPLITEAL BYPASS GRAFTING.


PARTIAL CYSTECTOMY WITH URETERAL REIMPLANTATION IN THE TREATMENT OF BLADDER NEOPLASM.


TECHNIQUE OF URETERO-ILEAL-CUTANEOUS ANASTOMOSIS ("THE ILEAL LOOP").


TREATMENT OF URINARY STRESS INCONTINENCE--A CURRENT APPRAISAL.


TRANSVERSE INCISIONS TO APPROACH TO METATARSOPHALANGEAL JOINTS.


HYSTERECTOMY: VAGINAL VERSUS ABDOMINAL.

HYSTERECTOMY: VAGINAL VERSUS ABDOMINAL.


SOME CONSIDERATIONS INVOLVING SURGERY OF THE SOLITARY KIDNEY.


A TECHNIQUE OF MAMMOGRAPHY.

A TECHNIQUE OF MAMMOGRAPHY.


TIBIAL OSTEOTOMY IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE.


CHROMOSOMES IN CLINICAL PRACTICE. I.

CHROMOSOMES IN CLINICAL PRACTICE. I.


CHROMOSOME ANALYSES IN THE UNIVERSITY COLLEGE HOSPITAL OF THE WEST INDIES. II.


CHRONIC DIFFUSE PROGRESSIVE INTERSTITIAL PULMONARY FIBROSIS IN A CHILD.


THE USE OF THE REITER PROTEIN COMPLEMENT FIXATION TEST IN THE DIAGNOSIS OF SYPHILIS IN JAMAICA.


THE AETIOLOGY OF TOXAEMIA OF PREGNANCY.

THE AETIOLOGY OF TOXAEMIA OF PREGNANCY.


SOME ASPECTS OF APPENDICITIS.

SOME ASPECTS OF APPENDICITIS.


THE CLINICAL FEATURES AND AETIOLOGY OF THE NEUROPATHIC SYNDROME IN  JAMAICA.


AN INFANT TREATMENT STATION.

AN INFANT TREATMENT STATION.


THE MICROBIOLOGY OF DISEASES IN JAMAICAN  CHILDREN.


METHODOLOGICAL STUDIES OF THE TECHNIQUE IN MEASURING NERVE FIBRE DIAMETERS.


CALIBRE SPECTRA OF SPINAL NERVES AND ROOTS IN NEWBORN MAN.


CALIBRE SPECTRA OF AFFERENT AND EFFERENT FIBRES IN MUSCLE NERVES OF THE ALBINO RAT'S HIND LIMB.


RETROGRADE CELLULAR CHANGES IN THE MESENCEPHALIC TRIGEMINAL NUCLEUS IN THE CAT FOLLOWING CEREBELLAR LESIONS.


FUNCTION OF THE GLUTEUS MAXIMUS MUSCLE. AN ELECTROMYOGRAPHIC STUDY.


ON THE PARADOXIDAL EFFECT OF SOME TWO-JOINT MUSCLES.


DEGENERATION OF THE MOTOR END-PLATES AFTER NEURECTOMY, IN THE RAT AND THE RABBIT.


THE NASUS EXTERNUS: AN INVESTIGATION OF THE VARIATIONS OF ITS MORPHOLOGICAL DETAILS.


AN HYPOTHESIS OF THE DEVELOPMENT OF COARCTATION IN MAN.


RESULTS OF THE SURGICAL AND RADIOLOGICAL TREATMENT OF CARCINOMA OF THE CERVIX AT THE WOMEN'S CLINIC, UNIVERSITY OF HELSINKI, IN 1953-1958.


PATTERN-DETECTION IN BRAIN-INJURED CHILDREN.


PERIPHERAL CIRCULATION IN PREGNANCY COMPLICATED BY DIABETES MELLITUS.


STUDIES ON PERIPHERAL CIRCULATION IN NORMAL PREGNANCY AND IN PREGNANCY COMPLICATED BY TOXAEMIA AND DIABETES MELLITUS.


SEEKING INFORMATION TO REDUCE THE RISK OF DECISIONS.


PARTIAL REINFORCEMENT IN THE FISH: EXPERIMENTS WITH SPACED TRIALS AND PARTIAL DELAY.


BOREDOM-INDUCED CHANGES IN PREFERENCES AMONG BETS.


TWO DIFFERENT AFTER-EFFECTS OF EXPOSURE TO VISUAL TILTS.


MILD STRESS AND PROBLEM-SOLVING.

MILD STRESS AND PROBLEM-SOLVING.


PREVIOUS AND CONCURRENT VISUAL EXPERIENCE AS DETERMINANTS OF PHENOMENAL SHAPE.


BACKGROUND REFLECTANCE AND THE CATEGORY-SCALING OF GRAY PAPERS.


THE EFFECT OF COMMITMENT TO CORRECT AND INCORRECT DECISIONS ON CONFIDENCE IN A SEQUENTIAL DECISION-TASK.


A STUDY OF THE VERBAL-TRANSFORMATION EFFECT.


TEMPORAL CHROMATIC INDUCTION: THE INTERACTION OF TWO SUCCESSIVE PULSES MEASURED BY SUBJECTIVE ESTIMATES.


TORQUE: A NEW DIMENSION IN TACTILE-KINESTHETIC SENSITIVITY.


FURTHER VALIDATION OF SUBJECTIVE SCALES FOR LOUDNESS AND BRIGHTNESS BY MEANS OF CROSS-MODALITY MATCHING.


DIFFERENCES IN PERCEIVED COLOR AS A FUNCTION OF CHARACTERISTIC COLOR.


VERBALIZATION AS A STIMULUS-TRACE IN GSR CONDITIONING.


ON THE MECHANISM OF TONAL CHROMA IN ABSOLUTE PITCH.


PERCEPTUAL INVARIANCE IN THE KINETIC DEPTH-EFFECT.


SKIN-CONDUCTANCE, ALPHA-ACTIVITY, AND VIGILANCE.


EVOCATION AND LEARNING TESTS FOR SECONDARY REINFORCEMENT.


PHYSICAL AND PERCEIVED VISUAL EXTENT: A NOTE ON GILINSKY'S EQUATIONS.


A DEVICE FOR POSITIONING TWO SHUTTERS.

A DEVICE FOR POSITIONING TWO SHUTTERS.


EDWARD WHEELER SCRIPTURE: 1864-1945.

EDWARD WHEELER SCRIPTURE: 1864-1945.


ANCHOR-EFFECTS AND THE SEMANTIC DIFFERENTIAL.


COMMENTS ON "SUBJECTIVE COLOR: A NEW METHOD OF PRODUCING THE PHENOMENON".


ACETYLCHOLINE IN ADRENERGIC TRANSMISSION.


SYNTHESIS OF POTENT ANTICANCER AGENTS. 1. 6-(1-PYRROLIDYL) PURINES, 6-(1-PIPERIDYL) PURINES AND THEIR NUCLEOSIDES.


SOME PHARMACOLOGICAL PROPERTIES OF M-(2-AMINOPROPYL)-PHENOL (ALPHA-METHYL-M-TYRAMINE).


BEHAVIOR OF PLASMA LIPOPROTEINS DURING EXCHANGE OF PHOSPHOLIPIDS BETWEEN PLASMA AND ERYTHROCYTES.


THE LIPID COMPOSITION OF NORMAL RAT THYMUS.


PHOSPHOLIPASE-A ACTIVITY OF MAMMALIAN TISSUES.


STUDIES ON THE COMPOSITION AND STRUCTURE OF THE PHOSPHATIDYLCHOLINE, PHOSPHATIDYLETHANOLAMINE AND TRIGLYCERIDE ISOLATED FROM RABBIT LIVER.


STUDIES OF THE ALPHA-GLYCERYL ETHER LIPIDS OCCURRING IN MOLLUSCAN TISSUES.


STUDIES ON THE CHEMISTRY OF MUCOLIPIDS: OCCURRENCE OF THE LONG-CHAIN BASE ICOSISPHINGOSINE, COMPOSITION OF FATTY ACIDS, FRACTIONATION ATTEMPTS.


FRACTIONATION AND CHARACTERIZATION OF WAX D, A MACROMOLECULAR PEPTIDOGLYCOLIPID OF MYCOBACTERIUM TUBERCULOSIS. I. BIOCHEMICAL INVESTIGATIONS OF WAX D OF HUMAN STRAIN H37RA.


THE INCORPORATION OF (2-14C)MEVALONATE AND (I-14C)ACETATE INTO LIPIDS OF AORTA AND HEART HOMOGENATES OF THE TURTLE (PSEUDYMIS SP.).


ON THE BIOSYNTHESIS OF ACETYL COENZYME A IN THE BRAIN. I. THE ENZYMIC FORMATION OF ACETYL COENZYME A FROM ACETATE, ADENOSINE TRIPHOSPHATE AND COENZYME A.


PHOSPHOLIPASE A ACTIVITY OF RAT-LIVER MITOCHONDRIA.


ASSOCIATION OF AMINO ACIDS WITH LIPIDS DURING THE COURSE OF ANTIBODY SYNTHESIS.


A SOLUBLE FATTY ACID SYNTHESIZING SYSTEM FROM LETTUCE CHLOROPLASTS.


STRUCTURAL STUDIES ON SULFATIDES IN METACHROMATIC LEUKODYSTROPHY.


CHAIN-SHORTENING OF STEARIC ACID IN THE INTACT RAT.


THE DISTRIBUTION OF PLASMA FATTY ACID TRANSFERASE-LIKE ACTIVITY IN RAT TISSUES.


THE COMPOSITION OF MILKFAT DIGLYCERIDES AND PARTIAL GLYCERIDES OBTAINED BY PANCREATIC-LIPASE HYDROLYSIS.


FAT METABOLISM IN HIGHER PLANTS. XXII. ENZYMIC SYNTHESIS OF 14-HYDROXY-11-EICOSENOIC ACID BY PARTICULATE PREPARATIONS OF AVOCADO MESOCARP.


AN INHIBITOR OF THE LIPOLYTIC REACTION FROM POST-HEPARIN PLASMA OF NORMAL DOGS.


LIPOLYTIC ACTIVITY AND PLASMA-FREE FATTY ACID LEVELS FOLLOWING THE ADMINISTRATON OF AN INHIBITOR OF THE CLEARING REACTION.


LIPID METABOLISM AND THE LAYING HEN. 3. PLASMA LIPOPROTEIN LIPASE IN RELATION TO THE ONSET OF LAYING.


FATTY ACID ADSORPTION BY LIVER- AND ADIPOSE-TISSUE PARTICLES.


LIPID RELEASE AND TRANSPORT IN INSECTS.

LIPID RELEASE AND TRANSPORT IN INSECTS.


MECHANISMS FOR REMOVAL OF CHYLE TRIGLYCERIDE FROM THE CIRCULATING BLOOD AS STUDIED WITH (14C)GLYCEROL AND (3H)PALMITIC ACID- LABELED CHYLE.


EVIDENCE FOR THE ACTIVATION OF FATTY ACIDS IN LIVER MITOCHONDRIA BY HIGH-ENERGY INTERMEDIATES FOR OXIDATIVE PHOSPHORYLATION.


PRESIDENT'S ADDRESS AT THE OPENING OF THE TWENTY-FIRST SESSION OF THE GENERAL DENTAL COUNCIL.


DENTISTRY IN THE UNITED KINGDOM; A SURVEY OF THE PRESENT POSITION AND FUTURE TRENDS.


SYMPOSIUM: THE USE OF CLOSED-CIRCUIT TELEVISION IN THE TEACHING OF DENTISTRY.


AN ASSESSMENT OF A MODIFIED ZINC OXIDE/EUGENOL CEMENT.


SIR JOHN HAMMOND, CBE, FRS. (23 FEBRUARY 1889-25 AUGUST 1964).


RECURRENT SWELLING OF THE PAROTID GLAND; REPORT OF A CASE DUE TO ALLERGY.


THE EFFECTS OF VARIATIONS IN THE FAT AND CARBOHYDRATE CONTENT OF THE DIET ON THE LEVELS OF MAGNESIUM AND CHOLESTEROL IN THE SERUM OF WHITE RATS.


THE MANGANESE AND COPPER OF CHICK BONE.

THE MANGANESE AND COPPER OF CHICK BONE.


THE RETENTION OF AN ORAL DOSE OF RADIOACTIVE MANGANESE IN THE PULLET AND THE EFFECTS ON RETENTION OF THE INTAKE OF INACTIVE MANGANESE.


COMPARISON OF NUTRITIONAL EFFECTS INDUCED IN CHICKS, RATS AND MICE BY RAW SOYA-BEAN MEAL.


ACTION OF FATS AND LINOLEIC ACID ON INTESTINAL SYNTHESIS OF THIAMINE IN THIAMINE-DEFICIENT RATS.


FACTORS AFFECTING THE VOLUNTARY INTAKE OF FOOD BY COWS. 7. THE BEHAVIOUR AND RETICULAR MOTILITY OF COWS GIVEN DIETS OF HAY, DRIED GRASS, CONCENTRATES AND GROUND, PELLETED HAY.


EFFECTS OF GIVING A FAT-FREE DIET FOR UP TO 10 WEEKS ON THE MALE WEANLING RAT.


VARIATIONS IN BODY-WEIGHT OF YOUNG WOMEN DURING THE MENSTRUAL CYCLE.


DAY-TO-DAY VARIATIONS IN BODY-WEIGHT OF YOUNG WOMEN.


AVAILABILITY OF SULPHUR AMINO ACIDS IN PROTEIN FOODS. 2. ASSESSMENT OF AVAILABLE METHIONINE BY CHICK AND MICROBIOLOGICAL ASSAYS.


NUTRITIVE VALUE OF NAVY BEANS (PHASEOLUS VULGARIS).


A MICROBIOLOGICAL METHOD FOR ASSESSING THE NUTRITIONAL VALUE OF PROTEINS. 4. ANALYSIS OF ENZYMICALLY DIGESTED FOOD PROTEINS BY SEPHADEX-GEL FILTRATION.


A NOTE ON KIDNEY SIZE IN CHRONIC HYPOVITAMINOSIS C.


OBSERVATIONS ON AUTOCLAVED, FUMIGATED AND IRRADIATED DIETS FOR BREEDING MICE.


EXPERIMENTAL OCCLUSION OF RETINAL ARTERIOLES: USING GRADED GLASS BALLOTINI.


RATE AT WHICH MUSCLE BECOMES JOINED TO SCLERA AFTER OPERATIONS OF RECESSION AND RESECTION. "The major contributions of surgical interest which have been made to our understanding of wound healing since Virchow and Paget rest with quantifying the rate of repair and the appraisal of factors which affect it." (Dunphy, 1960.)


PATHWAY OF CENTRIFUGAL FIBRES IN THE HUMAN OPTIC NERVE, CHIASM, AND TRACT.


METHOD FOR THE PRESERVATION AND STERILIZATION OF FRESH DONOR MATERIAL FOR FULL-THICKNESS KERATOPLASTY BY GRAMYCETIN.


UNTOWARD SEQUELS OF ARRUGA ENCIRCLEMENT FOR RETINAL DETACHMENT: REPORT ON 29 CASES.


THE RELATIONSHIP BETWEEN THE MYDRIATIC ACTION OF EPHEDRINE AND THE COLOUR OF THE IRIS.


ABNORMAL PROTEIN AND NUCLEIC ACID METABOLISM AS A CAUSE OF CATARACT FORMATION INDUCED BY NUTRITIONAL DEFICIENCY IN RABBITS.


REFRACTION IN FULL-TERM BABIES.

REFRACTION IN FULL-TERM BABIES.


GLUTEN AND MULTIPLE SCLEROSIS.

GLUTEN AND MULTIPLE SCLEROSIS.


FACTORS INFLUENCING NEPHELOMETRIC MEASUREMENTS IN THE MORRISEY-HARTOP CLOSURE PROCEDURE.


SINGLE DOSE DISPOSABLE SYRINGES--THE TUBEX SYSTEM.


SANITATION AND MAINTENANCE OF STERILE AREAS.


DIABETES INSIPIDUS. DIFFICULTIES IN DIAGNOSIS AND TREATMENT; USE OF SYNTHETIC LYSINE-8 VASOPRESSIN IN PATIENTS INTOLERANT OF OTHER THERAPY. Frequent errors in the diagnosis of diabetes insipidus arise from (1) failure to produce an adequate stimulus for release of antidiuretic hormone, and (2) failure to appreciate acute or chronic changes in renal function that may obscure test results. Properly timed determination of body weight, urine volume and serum and urine osmolarity during the course of water deprivation, and comparison of these values with those obtained after administration of exogenous vasopressin, eliminates most diagnostic errors. In four patients who had experienced local and systemic reactions to other exogenous forms of vasopressin, diabetes insipidus was satisfactorily controlled by administration of synthetic lysine-8 vasopressin in nasal spray. A fifth patient was also treated satisfactorily with this preparation.


SIGMOIDOSCOPIC EXAMINATION. ROUTINE USE FOR PATIENTS IN HOSPITAL. Routine sigmoidoscopic examination as a screening method for detecting cancer of the colon was evaluated during a recent four-year period. In 18,120 patients, this examination discovered 1,087 with unsuspected benign polyps (6.0 per cent), 51 patients with unsuspected malignant polyps (0.28 per cent), and 36 patients with unsuspected cancer (0.2 per cent). These 36 cases of cancer of the colon made up 24.8 per cent of all the cancers that occurred in the lower sigmoid and rectum (within 25 cm of the anorectal junction) in the series.


VIRUSES AND CANCER.

VIRUSES AND CANCER. The answer to the important question, "Do viruses play a role in human cancer?" is still unknown. Although many scientists think that they may play a role, straightforward attempts to isolate human tumor viruses in animals or in tissue cultures have failed. Possibly the most sensitive test object, newborn human infants, of course cannot be used as test objects, and this may explain the failure to isolate human tumor viruses. At present, it would appear that the best means of tackling the problem of viral-induced carcinogenesis is to study the basic characteristics of known tumor viruses and the basic aspects of their interactions with cells. Both RNA-containing and DNA-containing viruses, two obviously different classes of virus, can cause cancer and therefore both classes must be studied in order to obtain a complete picture of the role of viruses in causing cancer in animals and cell transformation in vitro. Such basic studies already have yielded information of great importance to general biology.A number of exciting developments have occurred in the area of virus-induced cancer. One of these is the oncogenic capacity in hamsters of certain human adenoviruses, and an intensive probe of their possible role in human cancer is in progress. Another is the detection by electron microscopy of virus-like particles in the tissues and serum of patients with leukemia. Rigid criteria have been suggested to establish etiologic significance of viruses recovered from human cancer tissues and of the virus-like particles observed by electron microscopy in serum or malignant tissues from cancer patients. If viruses are eventually found to play a role in human cancer, then perhaps the disease can be prevented by vaccines and treated with antiviral substances.


CANCER QUACKERY: ITS CONTROL IN CALIFORNIA.


SKIN CANCER AS A CAUSE OF DEATH.

SKIN CANCER AS A CAUSE OF DEATH. An estimated 6,000 new cases of skin cancer (excluding melanoma) occur each year in California, and vital statistics data show about 125 deaths attributed annually to this cause. A study of deaths attributed to skin cancer indicates that the true number was probably between 40 and 50. More than half of those who died were 75 years of age or over. Delay by the patient was the factor occurring most often in the deaths which could have been avoided.


TREATMENT OF BARBITURATE POISONING. THE USE OF PERITONEAL DIALYSIS. In a case of severe phenobarbital poisoning successfully treated by peritoneal dialysis, a total of 2.24 gm of the drug was removed during two periods of dialysis. (The patient is believed to have taken 10 gm.) This compares favorably with amounts that can be removed by hemodialysis. The technique is simple, safe and effective. It should be considered for use in cases meeting the criteria for its use.


SERUM CALCIUM DECREASE AFTER PURGATION. TREATMENT OF HYPERCALCEMIA ASSOCIATED WITH MAMMARY CANCER.


REGIONAL ENTERITIS IN SIBLINGS.

REGIONAL ENTERITIS IN SIBLINGS.


RADIATION THERAPY OF CANCER.

RADIATION THERAPY OF CANCER.


TREATMENT OF RIEDEL'S THYROIDITIS WITH DESICCATED THYROID.


POST-TREATMENT REACTIONS IN CATTLE DURING EXTENSIVE FIELD TESTS OF SYSTEMIC ORGANOPHOSPHATE INSECTICIDES. Treatment, grub infestation, and post-treatment reaction data is given for 11,537 range-managed beef cattle, of all age classes, treated for grub and louse control with various systemic organophosphate insecticides during the period 1956 to 1964. Two cows died from perforation of the throat during administration of Trolene boluses. Of 6,858 calves, 71 showed adverse reactions with 4 dead. Of 4,679 cattle over one year of age, 3 showed adverse reactions with one death. No typical organophosphate poisoning occurred. One death resulted from a paraplegic reaction and necropsy showed spinal nerve damage of the type often associated with the presence of H. bovis grubs in the spinal canal. Seventy-three reactions, with 4 deaths, were of a bloat-salivation type, and necropsies of 3 indicated anaphylaxis, the other an extensive pharyngeal - esophageal necrosis. Reactions were directly associated with grub abundance. Other stress factors coincident to insecticide treatment, such as Bang's vaccination and dehorning, did not enhance reactions, and incipient coccidiosis did not predispose to reactions, nor did insecticide treatment increase susceptibility to coccidiosis. It is concluded that the observed adverse reactions resulted from the killing of grubs situated in the animal tissues.


ADDITIONAL INFORMATION PERTAINING TO SALMONELLA TYPES FOUND IN THE MESENTERIC LYMPH NODES OF STRAY DOGS. A number of different Salmonella types were found in the mesenteric lymph nodes of stray dogs although none were isolated from the feces of these same animals.


SIMULTANEOUS GROWTH OF RABIES AND CANINE DISTEMPER VIRUSES IN CHICK EMBRYOS. Rabies virus and canine distemper virus were grown simultaneously, and possibly symbiotically, in the same chick embryos. There seemed to be no adverse effect on either virus when cultured in such manner.Bivalent vaccines for rabies and canine distemper were produced. The potencies and the virus titers of such vaccines were comparable to those of rabies vaccine and canine distemper vaccine produced separately.


LIVER VITAMIN A STORAGE IN FATTENING CATTLE FOLLOWING INTRARUMINAL OR INTRAMUSCULAR INJECTION OF VITAMIN A. The effect of intramuscular or intraruminal injection of 1 million I.U. of an emulsifiable vitamin A preparation upon liver vitamin A stores in fattening steers was investigated. Pre-injection liver stores were 52 mcg vitamin A/gm fresh liver. At 7 days post-injection, these stores had increased to an average of 88 mcg vitamin A/gm fresh liver. Thereafter, the liver vitamin A stores declined until at 73 days post-injection they were approximately 28 mcg vitamin A/gm fresh liver. During depletion the pre-injection liver vitamin A levels were reached between 30-35 days post-injection. The method of administration had little effect on repletion of liver vitamin A stores; however, the steers injected intramuscularly showed a slightly slower depletion of liver vitamin A, than those injected intraruminally. Very little difference was observed in average daily weight gains between the two methods of vitamin A administration.


STUDIES ON TRANSMISSIBLE GASTROENTERITIS OF SWINE. I. THE ISOLATION AND IDENTIFICATION OF A CYTOPATHOGENIC VIRUS OF TRANSMISSIBLE GASTROENTERITIS IN PRIMARY SWINE KIDNEY CELL CULTURES. Two virus isolates from transmissible gastroenteritis (TGE) of swine were adapted to grow in primary swine kidney cells. Growth of the virus was indicated by the resistance of the infected cells to the cytopathic effect of a virus diarrhea virus of cattle, and by the development of large round cells on the cell sheet. Evidence that these virus isolates were TGE was obtained by the development of signs of the disease followed by death of exposed SPF pigs, or the resistance of the recovered pigs to further signs of disease when they were exposed to virulent TGE contained in virus bearing intestinal tissue. The in vitro and in vivo serum neutralization tests, along with staining of infected cells by fluorescein conjugated TGE antiserum, gave further indication of the specific nature of the virus growing in the cell cultures.


THE USE OF FLUORESCENT ANTIBODY STAINING IN THE DIAGNOSIS OF RABIES. Brain material from 750 domestic and wild animals submitted to this laboratory for rabies diagnosis was studied by the following three methods: a) microscopic examination of Williams' stained impressions, b) mouse inoculation test, and c) microscopic examination of impressions stained with fluorescein-tagged antibodies. The purpose of this investigation was to compare the sensitivity of the fluorescent antibody technique with that of two classical methods, when applied to the routine diagnosis of rabies. From the results obtained by one or the other method of study, 175 specimens were diagnosed as positive. Of these, only 58 (33 per cent) were detected by the examination of Williams' stained impressions. On the other hand, two rabid cases were missed by the mouse inoculation test, and four by the fluorescent antibody technique. Without being completely reliable, the last two methods proved to be almost equally sensitive and much more so than the examination of Williams' stained impressions.


EPIZOOTIOLOGY ON MINK ENTERITIS. II. MUSCA DOMESTICA L AS A POSSIBLE VECTOR OF VIRUS. The significance of the house fly M. domestica L as a vector of ME was studied. MEV was transmitted from infected to susceptible mink by flies having unlimited contact with both. Disease was also induced by feeding infected flies to susceptible mink.


FRACTIONATION ON CROSS-LINKED DEXTRAN, SEPHADEX G-25, OF SERA FROM SHEEP INFECTED WITH JOHNE'S BACILLI. PRELIMINARY REPORT. Ten sera collected during the winter months from six sheep infected with Johne's bacilli were fractionated on Sephadex G-25 columns, and all fractions tested for complement-fixing antibody, anticomplementary properties and for supplementing and inhibitory activities when added to complement-fixation tests of a heterologous antigen-antibody system: bovine or ovine antiserum with Brucella abortus antigen. Serum from a normal sheep was similarly fractionated and examined. The complement-fixing activity with a carbohydrate fraction of Johne's bacilli was confined principally to supernatant fractions of the earlier eluates containing the greater part of the serum proteins. Some of the unheated earlier and later fractions displayed a limited degree of supplementing effect. Inhibitory activity was demonstrated by certain of the earlier and later eluates after they had been heated, particularly those of antisera with initially low complement-fixing antibody titer.


HOG CHOLERA. II. RELIABILITY OF THE AGAR DOUBLE DIFFUSION PRECIPITATION TEST FOR THE DIFFERENTIATION OF H.C. VIRUS FROM OTHER INFECTIOUS AGENTS IN SWINE TISSUE. The specificity in the agar diffusion precipitation test of the reaction between the antigen of hog cholera virus diffusing from infected tissues and its homologous antibody was verified. Alternate freezing and thawing of infected tissues was found to give optimum release of the antigen from fresh tissue frozen for 18 hours. A study of the effect of the size and age of pigs upon the diffusion of the antigen from tissues showed that tissues from pigs of less than 250 lbs. gave good results provided the tissues were from animals showing gross clinical manifestations. Specimens from infected breeding sows and dead animals usually did not give a reaction.


CYTOLOGY OF PHAGE-INFECTED STREPOMYCES GRISEUS HYPHAE.


EXTRACELLULAR ENZYMES FROM STRAINS OF SORANGIUM.


MOTILE DAUGHTER COLONIES OF CLOSTRIDIUM CAPITOVALE.


EFFECT OF DIVALENT CATIONS ON THE ACTIVITY OF BACTERIAL UREASE.


POLYSACCHARIDE COMPONENTS OF NEUROSPORA CRASSA HYPHAL WALLS.


MINIMAL ANTIGENIC CONSTITUTION OF 28 STRAINS OF RHIZOBIUM JAPONICUM.


EFFECT OF CARBOHYDRATES ON TOXINOGENESIS BY CLOSTRIDIUM PERFRINGENS TYPE D.


ORGANIC COMPOUNDS IN THE SPENT MEDIUM OF FERROBACILLUS FERROOXIDANS.


CYTOLOGY OF THE HUMAN AMNION: A CORRELATION WITH CELL CULTURE.


EFFECT OF CONTROLLED PH ON TOXINOGENESIS BY CLOSTRIDIUM PERFRINGENS TYPE D.


PIGMENTS OF ELSINOUE SPECIES. I. PIGMENT PRODUCTION BY ELSINOUE SPECIES; ISOLATION OF PURE ELSINOCHROMES A, B, AND C.


SIZE OF INOCULUM, STIMULATION, AND INHIBITION OF GROWTH IN ASPERGILLUS ORYZAE.


ISOLATION AND SOME PHYSIOLOGICAL FEATURES OF SAPROSPIRA THERMALIS.


THE PRODUCTION OF IMMUNO-CONGLUTININ. 8. THE EFFECT OF 6-MERCAPTOPURINE AND COLCHICINE.


GROWTH CHARACTERISTICS OF PHAGES OF AGROBACTERIUM RADIOBACTER.


A QUANTITATIVE STUDY OF THE EFFECTS OF NATURALLY OCCURRING SUPPLEMENTS ON THE GROWTH OF RAINBOW TROUT (SALMO GAIRDNERI) GONADAL CELLS.


ON THE MEASURED AND DIRECTLY ESTIMATED CAPACITY OF THE SKULL.


NERVOUS SYSTEM ALTERATIONS AFTER SUBOCCIPITAL ADMINISTRATION OF ACTH.


TREATMENT OF MYOCARDIAL INFARCTION WITH CORTISONE.


ON THE BALLISTOCARDIOGRAM IN ADULT SUBJECTS.


POSSIBLE CARDIAC AND RENO-VASCULAR COMPLICATIONS OF SANSERT THERAPY.


SOFT TISSUE RETENTION OF 226RA IN THE BEAGLE.


RADIOCHEMICAL DETERMINATION OF PLUTONIUM-239 IN LOW-LEVEL ENVIRONMENTAL SAMPLES BY ELECTRODEPOSITION.


THE DETERMINATION OF BODY BURDENS OF RADIONUCLIDES BY COMPUTER ANALYSIS OF GAMMA-RAY SPECTRAL DATA.


DECONTAMINATION FOLLOWING A NUCLEAR EXCURSION.


DETERMINATION OF RADIATION EXPOSURE FROM OVEREXPOSED AGPO3 MICRODOSIMETER.


THE RESPONSE OF A NEUTRON-INSENSITIVE GAMMA RAY DOSIMETER AS A FUNCTION OF PHOTON ENERGY.


SR-90 REMOVAL IN VEGETABLES PREPARED FOR HOME CONSUMPTION.


THE PERSONAL RETRIEVAL OF HEALTH PHYSICS INFORMATION.


THE HEALTH PHYSICS RESEARCH REACTOR.

THE HEALTH PHYSICS RESEARCH REACTOR.


METHOD FOR BETA-GAMMA HAND AND SHOE COUNTING UNDER VARYING BACKGROUND CONDITIONS.


THE CESIUM-137 CONTENT OF BEEF FROM DAIRY AND FEED-LOT CATTLE.


PARENTAL AGE AND MALFORMATIONS.

PARENTAL AGE AND MALFORMATIONS.


PONDERAL INDEX OF FATHERS AND SEX RATIO OF CHILDREN.


BLOOD GROUPS IN THE THARUS OF UTTAR PRADESH AND THEIR BEARING ON ETHNIC AND GENETIC RELATIONSHIPS.


METHODS OF ANALYSIS OF THE GENETIC COMPOSITION OF A HYBRID POPULATION.


KLIPPEL FEIL SYNDROME. A BRIEF REVIEW WITH REPORT OF 7 CASES.


RECENT ADVANCES IN NUTRITION AND DENTAL CARIES.


PHYSIOLOGY OF OLD AGE. I. EFFECTS AND CAUSES OF AGING.


CONGENITAL ATRESIA OF THE PAROTID DUCT IN A HORSE.


TOXICITY OF THE INSECTICIDE COMPOUND 4072 IN CATTLE.


SURGICAL CORRECTION OF POLYDACTYLISM IN THE HORSE.


COCCIDIOSIS DUE TO EIMERIA AHSATA IN FEEDLOT LAMBS IN ILLINOIS.


BIOLOGICAL RESIDUES--A CHALLENGE TO VETERINARIANS.


CANINE BABESIOSIS IN OKLAHOMA.

CANINE BABESIOSIS IN OKLAHOMA.


AN INEXPENSIVE TRANSISTORIZED CURRENT GENERATOR FOR USE IN ELECTRICAL ANESTHESIA.


CLINICO-PATHOLOGIC CONFERENCE: FROM THE SCHOOL OF VETERINARY MEDICINE UNIVERSITY OF PENNSYLVANIA.


EFFICACY OF VARIOUS DIURETICS IN NORMAL DOGS.


THE FINAL COMMON PATHWAY.

THE FINAL COMMON PATHWAY.


DERMATOGLYPHIC RESEARCH.

DERMATOGLYPHIC RESEARCH.


ACUTE ISCHEMIC INFARCTION OF THE GASTROCNEMIUS MUSCLE SIMULATING DEEP VEIN PHLEBITIS.


CLINICAL RECOGNITION OF CRYPTOGENIC MYCOTIC ANEURYSM.


LONG TERM FOLLOW-UP OF HOMOGRAFTS USED IN THE TREATMENT OF COARCTION OF THE AORTA.


THE USE OF THAM BUFFERED ACID-DEXTROSE-CITRATE BLOOD FOR EXTRACORPOREAL CIRCULATION.


THE APPLICATION OF A WIRE VALVOTOME FOR A COMMISSUROTOMY.


THE EFFECTS OF HYPOTHERMIA ON THE METABOLISM OF THE POST-ARRESTED CANINE HEART.


SUB-AORTIC MUSCULAR STENOSIS: A NEW SURGICAL TECHNIQUE FOR REPAIR.


INDICATION FOR SHUNT OPERATION IN INFANTS WITH STENO-FALLOT'S TETRALOGY.


SOME ASPECTS OF VITAMIN B 12 AND PROBLEMS RELATED TO ITS DEFICIENCY.


BRAIN MITOCHONDRIA. 3. FATTY ACID OXIDATION BY BOVINE BRAIN MITOCHONDRIA.


STIMULATION OF MITOCHONDRIAL NADH OXIDASE BY BRAIN MITOCHONDRIAL EXTRACTS.


OCCURRENCE AND DISTRIBUTION OF N-ACETYLHISTIDINE IN BRAIN AND EXTRACEREBRAL TISSUES OF POIKILOTHERMAL VERTEBRATES.


FIXATION OF TETANUS TOXIN BY SUBCELLULAR FRACTIONS OF BRAIN.


STUDIES OF TURNOVER IN MAMMALIAN SUBCELLULAR PARTICLES: BRAIN NUCLEI, MITOCHONDRIA AND MICROSOMES.


CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATE.


THE ENZYMIC MEASUREMENT OF GAMMA-AMINOBUTYRIC-ALPHA-OXOGLUTARIC TRANSAMINASE.


EVALUATION OF THE RADIOISOTOPE RENOGRAM IN EXPERIMENTAL RENAL ARTERY STENOSIS.


UPTAKE OF D- AND L-ALANINE BY RAT BRAIN SLICES.


COMPETITIVE BINDING OF NA, K, MG AND CA IONS TO CEREBROSIDE SULPHURIC ACID.


INTERNAL DOSE CALCULATION FOR 99MTC.

INTERNAL DOSE CALCULATION FOR 99MTC.


SMALL VEIN RECONSTRUCTION.

SMALL VEIN RECONSTRUCTION.


AN ISOTOPIC METHOD FOR ESTIMATION OF URINARY POTASSIUM.


CONGENITAL AND JUVENILE HYPOTHYROIDISM DUE TO THYROID DYSGENESIS.


EXPERIMENTAL RESEARCH AND STATISTICAL DATA IN VENTRICULAR FIBRILLATION  FOLLOWING MYOCARDIAL INFARCTION AND CARDIAC RESUSCITATION.


APPEARANCE AND REGRESSION OF PATHOLOGICAL CHANGES IN THE PULMONARY ARTERIAL WALL AFTER REPEATED AIR EMBOLISM.


SURGICAL TREATMENT OF PULMONARY STENOSIS USING EXTRACORPOREAL CIRCULATION.


UNUSUAL COMPLICATION AFTER OPEN VALVULOTOMY IN PULMONARY STENOSIS.


PURIFICATION OF RADIOACTIVE SODIUM O-IODOHIPPURATE USING GEL FILTRATION WITH DEAE-SEPHADEX.


DIRECTORY OF MEMBERS OF THE SOCIETY FOR PROJECTIVE TECHNIQUES AS OF MARCH 1, 1965.


CLINICAL EXPERIENCES WITH CINECORONARY ARTERIOGRAPHY.


EFFECT OF IRRADIATION ON FERROKINETICS OF CROSS-CIRCULATED DOGS.


A REVIEW OF SENTENCE COMPLETION METHODS IN PERSONALITY ASSESSMENT.


NORMATIVE DATA ON A SELF-ADMINISTERED PROJECTIVE QUESTION FOR CHILDREN.


THE STIMULUS VALUE OF THE TAT.

THE STIMULUS VALUE OF THE TAT.


PERCEPTUAL LEARNING IN THE REACTIVE-PROCESS SCHIZOPHRENIAS.


THE RORSCHACH TEST AS A RESEARCH DEVICE FOR THE IDENTIFICATION, PREDICTION AND UNDERSTANDING OF SUICIDAL IDEATION AND BEHAVIOR.


THE ACCEPTABILITY AND EXPRESSION OF ATTITUDES ASSOCIATED TO THE RORSCHACH HUMAN MOVEMENT RESPONSE.


PRIMARY AND SECONDARY PROCESS THINKING IN TWO TYPES OF SCHIZOPHRENIA.


TERATOGENIC ACTION OF SALICYLATES IN MICE. EFFECT ON  MUCOPOLYSACCHARIDE SYNTHESIS.


EXPERIMENTAL STUDY ON HYPERTENSION AND SALT METABOLISM. II. THE INFLUENCE OF SODIUM CHLORIDE ON VARIOUS FORM OF HYPERTENSION.


FINE STRUCTURES OF THE SYNOVIAL TISSUES IN RHEUMATOID ARTHRITIS.


THE COMBINED ACTION OF ANTI-TUMOR CHEMICALS AND 60-CO GAMMA-RAY ON THE MOUSE STRAIN L CELLS CULTURED IN VITRO. II. EFFECT OF ALKYLATING AGENTS AND ANTIBIOTICS.


PLASMINOGEN ACTIVATOR IN THE CYTOPLASMIC GRANULES OF RAT KIDNEY: STUDIES ON EXTRACTION BY ISOTONIC AND HYPERTONIC SALT SOLUTIONS.


IMMUNE RESPONSE OF EHRLICH ASCITES TUMOR CELLS IRRADIATED IN VITRO.


FACIAL BASE PLANE OF JAPANESE STUDENTS.

FACIAL BASE PLANE OF JAPANESE STUDENTS.


THE EFFECTS OF 4, 4'-DIETHYLAMINOETHOXY HEXESTROL DIHYDROCHLORIDE (CORALGIL) ON THE CORONARY CIRCULATION.


IMPROVED ZAFFARONI SYSTEMS FOR THE PAPER CHROMATOGRAPHY OF C19 STEROIDS.


HISTOCHEMICAL DEMONSTRATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN MUSCLE.


PROTECTIVE ACTION OF LEMON JUICE AND ASCORBIC ACID AGAINST LETHALITY AND CONVULSIVE PROPERTY OF STRYCHNINE.


ACTION OF A LIVER LYSATE ON HEPATIC REGENERATION.


POST INFECTION CHANGES IN THE CARBOHYDRATE CONTENTS OF BANANA FRUITS CAUSED BY BOTRYODIPLODIA THEOBROMAE PAT.


NERVOUS CONTROL OF METABOLISM DURING TEMPERATURE ACCLIMATION OF FISH.


PEDIATRICS 1984. II.

PEDIATRICS 1984. II.


CROHN'S DISEASE WITH ULCERATION OF THE LARGE BOWEL.


CONGENITAL THYROTOXICOSIS WITH HEPATOSPLENOMEGALY AND THROMBOCYTOPENIA, ASSOCIATED WITH ANIRIDIA AND DISLOCATED LENSES.


A NEW CONCEPT OF TEMPERATURE CONTROL IN THE HYPOTHALAMUS.


OPIATE ADDICTION.

OPIATE ADDICTION.


RECENT ADVANCES IN LOCAL ANALGESIA. TOXICITY AND CLINICAL USE OF PILOCAINE.


MALIGNANT HAEMANGIO-ENDOTHELIOMA.

MALIGNANT HAEMANGIO-ENDOTHELIOMA.


DERMATOMYOSITIS.

DERMATOMYOSITIS.


RECENT ADVANCES IN LOCAL ANALGESIA. SOME PHARMACOLOGICAL PROPERTIES DETERMINING ACTION AND TOXICITY OF LOCAL ANAESTHETICS.


GENERALIZED PUSTULAR PSORIASIS (VON ZUMBUSH) WITH EPISODIC HYPOCALCAEMIA.


DRUG ADDICTION. PHARMACOLOGICAL ASPECTS OF ADDICTION TO MORPHINE AND OTHER DRUGS.


THYROID ACROPACHY, CIRCUMSCRIBED MYXOEDEMA AND EXOPHTHALMOS.


POLYCYTHAEMIA RUBRA VERA: SKIN ERUPTION UNDIAGNOSED.


PORPHYRIA CUTANEA TARDA PRESENTING AS 'NEUROTIC EXCORIATIONS'.


SPONTANEOUS RUPTURE OF THE OESOPHAGUS WITH RECOVERY FOLLOWING REPAIR.


OSTEOPOROSIS--SOME STRUCTURAL ASPECTS.

OSTEOPOROSIS--SOME STRUCTURAL ASPECTS.


MALIGNANT NONFUNCTIONING ISLET CELL TUMOUR OF THE PANCREAS IN A 14-YEAR-OLD GIRL.


A STUDY OF THE TREATMENT OF OSTEOPOROSIS WITH FLUORIDE THERAPY AND HIGH CALCIUM INTAKE.


SPINAL OSTEOPOROSIS AND THE MENOPAUSE.

SPINAL OSTEOPOROSIS AND THE MENOPAUSE.


OPEN ACCESS TO INVESTIGATIONAL PROCEDURES FOR THE GENERAL PRACTITIONER. Dr David Wheatley produces figures to show that, in his area of practice, open access to pathology at one large hospital has resulted in less work being undertaken than at another large hospital, where such access is unavailable. He stresses the necessity for open access to such services, including X-rays and ECGs, if a high standard of general practice is to be maintained.Professor R E Steiner, although agreeing with the concept of open access for the general practitioner, believes that at present this should be limited by the facilities available. He describes such a service which has been made available to general practitioners at Hammersmith Hospital for diagnostic X-rays, and stresses the importance of personal consultation between specialist and general practitioner.Dr D Stark Murray describes the system of complete open access to the pathology laboratory, which has been in operation at Kingston Hospital over the past twenty-five years. He shows the use which has been made of the service by local general practitioners and stresses that this is an essential part of the health service.


ACCESS FOR GENERAL PRACTITIONERS TO X-RAY DIAGNOSTIC DEPARTMENTS.


OPEN ACCESS TO INVESTIGATIONAL PROCEDURES FOR THE GENERAL PRACTITIONER. THE PATHOLOGICAL LABORATORY.


ORAL ULCERATION. MEDICAL ASPECTS.

ORAL ULCERATION. MEDICAL ASPECTS.


ORAL ULCERATION AS A MANIFESTATION OF SOME DERMATOSES.


'APHTHOUS' AND HERPETIC LESIONS OF THE ORAL MUCOSA.


DRUG ADDICTION. ADOLESCENT DRUG TAKING.

DRUG ADDICTION. ADOLESCENT DRUG TAKING.


THE PRODROMAL PHASE OF THE DEPRESSIVE PSYCHOSIS.


A CLINICAL AND METABOLIC STUDY OF DOPA (3, 4-DIHYDROXYPHENYLALANINE) AND METHYLDOPA IN HUNTINGTON'S CHOREA.


THE ACTION OF BROMINE ON DELTA -7-ERGOSTENE AND CHOLESTENE DERIVATIVES.


THE SYNTHESIS OF SOME 21-CHLORO- 16A, 17A-ACETONIDES.


C-5 SUBSTITUTED 19-NORSTEROIDS.

C-5 SUBSTITUTED 19-NORSTEROIDS.


STEROIDS. CCLXXVII. SPECTRA AND STEREOCHEMISTRY. XIX.  A COMPARATIVE STUDY OF THE NMR SPECTRA OF SOME STEROIDS IN FIVE SOLVENTS.  THE STRUCTURE OF 'ACIPENSEROL-A'.


STEROIDS. CCLXXIV. BIOLOGICALLY-ACTIVE LABILE ETHERS. IV. THE SYNTHESIS OF 22-OXA-25-AZACHOLESTEROL AND RELATED COMPOUNDS.


STEROIDS. CCLXXII (1). BIOLOGICALLY-ACTIVE LABILE ETHERS. 3. (2). A NEW CLASS OF POTENT ESTROGENS.


EFFECT OF ACTH IN VIVO ON THE CHOLESTEROL SIDE-CHAIN CLEAVING ENZYME AND ON STEROID HORMONE PRECURSOR CHOLESTEROL IN RAT ADRENAL GLAND.


EFFECTIVENESS OF TOPICAL APPLICATION OF A NUMBER OF PROGESTINS.


THE MONOHYDROXYLATION OF 17 BETA - ESTRADIOL AT THE 15 ALPHA-, 16 ALPHA-, AND 16 BETA- POSITIONS BY BOVINE ADRENAL PERFUSION.


DETERMINATION OF ANDROSTERONE, ETIOCHOLANOLONE AND DEHYDROEPIANDROSTERONE IN URINE BY GAS-LIQUID CHROMATOGRAPHY.


ACUTE INHIBITORY ACTION OF GLUCOCORTICOIDS ON THE UPTAKE OF SULPHUR BY BONE TISSUE IN VIVO.


ADRENOCORTICAL BLOCKADE AND THE TRANSAMINASE RESPONSE TO EXERCISE.


PREFERENTIAL UPTAKE OF 6, 7-H3-ESTRADIOL BY THE ENDOMETRIUM OF THE RAT UTERUS.


DOES THE NERVOUS SYSTEM POSSESS ANY INFLUENCE ON HEART DETERMINATION AND DIFFERENTIATION?


HISTOCHEMISTRY AND CYTOCHEMISTRY OF EXPERIMENTALLY DENERVATED GUINEA PIG MUSCLE. I. HISTOCHEMISTRY.


TOPOGRAPHY OF THE HUMAN LABYRINTH IN THE TEMPORAL BONE.


THE CRYSTAL AND MOLECULAR STRUCTURE OF BETA-ALANINE.


CYTOLOGY AND THE CYTOCHEMISTRY OF THE SPERMATOGENESIS OF MERIONES HURRIANAE JERDEN, THE INDIAN GERBIL.


NATURE AND INHERITANCE OF THE RESISTANCE OF INBRED MICE TO TUMOR INDUCTION BY  POLYOMA VIRUS.


LIGHT EMISSION FROM THE LUMINOUS FUNGUS COLLYBIA VELUTIPES UNDER DIFFERENT NUTRITIONAL CONDITIONS.


TRANSCARINAL BRONCHOSCOPIC NEEDLE BIOPSY.


MANAGEMENT OF CHRONIC ARTERIOSCLEROTIC HEART DISEASE WITH FAILURE AND/OR ANGINA.


MICROFLUOROSCOPIC STUDIES OF PORPHYRINS IN TISSUES IMBEDDED IN  PARAFFIN.


DEGRADATION OF 5-ALLYL-5-(2'-HYDROXYPROPYL)-BARBITURIC ACID.


BIOLUMINESCENCE AND OTHER CHARACTERISTICS OF COLLYBIA VELUTIPES.


PHASE CINEMICROGRAPHIC OBSERVATIONS ON CULTURED CELLS. II. MASS MOVEMENT OF CYTOPLASM IN EUPHORBIA MARGINATA.


PHAGOCYTOSIS OF ATYPICAL MYCOBACTERIA FROM VARIOUS SOURCES.


STUDIES ON THE EFFECT OF LOW-FREQUENCY MECHANICAL VIBRATION ON THE LIVER AND SPLEEN OF MATURE, FETAL AND NEONATE RATS.


THE INFLAMMATORY RESPONSE TO INJECTED MICROCRYSTALLINE MONOSODIUM URATE IN NORMAL, HYPERURICEMIC, GOUTY, AND UREMIC SUBJECTS.


EFFECT OF MANGANESE IN EXPERIMENTAL ANEMIA IN RATS. FIRST REPORT.


PHARMACOLOGIC PROPERTIES OF GAMMA-AMINOBUTYRIC ACID AND ITS DERIVATIVES. II. EFFECT ON THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM.


ANTICANCER TESTING OF THE FAR EASTERN PLANT PRODUCTS. 2.


EXPERIMENTAL STUDY ON MYCOTIC EPIDERMAL REACTION. (3).  EPIDERMAL FEATURE OF PAPULONECROTIC DERMATOPHYTID ARTIFICIALLY PRODUCED.


PHARMACEUTICAL STUDIES ON OINTMENTS AND EXTERNAL REMEDIES. (10). SOLUBILITY AND COMPATIBILITY OF POLYETHLENGLYCOL (PEG), POLYPROPYLENGLYCOL (PP) AND GLYCERIN-POLYPROPYLENGLYCOL-ETHER (GP).


PHOTOSENSITIVITY AND SIDERO-HEPATOSIS IN PORPHYRIA CUTANEA TARDA.


HEPATIC AND RENAL LESIONS IN A CASE OF TETRACYCLINE TOXICITY DURING LONG-TERM ESTROGEN THERAPY AFTER ORCHIECTOMY.


CLINICAL RESULTS OF THROMBOENDARTERECTOMY FOR PERIPHERAL ATHEROSCLEROTIC OCCLUSIVE DISEASE. Thromboendarterectory of atherosclerotic vessels may restore luminal flow by removal of the occluding thrombus and thickened, ulcerated intima. This operation has been performed on 43 occasions for aortoiliac and femoropopliteal occlusive lesions with significant distal ischemia. The early and late results have been entirely satisfactory, confirming the worth and durability of the procedure, particularly for limb salvage. The widespread and progressive character of the atherosclerotic process, however, may compromise the operative and late results by involvement of vital arteries or distal small vessels. Complete angiographic assessment from the abdominal aorta to beyond the popliteal bifurcation is essential in the proper selection of patients. Thrombo-endarterectomy is recommended for the management of segmental occlusive lesions primarily, but gratifying results may be obtained in extensively diseased arteries unsuitable for bypass grafting.


THE ACUTE TOXICITY OF TANNIC ACID ADMINISTERED  INTRAGASTRICALLY. The LD(50) +/- S.E. of tannic acid given orally to albino rats was found to be 2.26+/-0.083 g. per kg. body weight, which is higher than its apparent LD(50) when given per rectum. The immediate cause of death was respiratory failure preceded by convulsions when death occurred early and by hypothermic cachexia when death was delayed. Death was associated with a progressively developing hepatic necrosis and nephritis and a temporary acute gastroenteritis. It was accompanied by loss of weight and edema in many organs, evidence of stimulation of the spleen, adrenal cortex and testes, and atrophy of the thymus. Recovery in survivors was associated with a temporary increase in weight of the spleen and testes and persistence of loss of weight in the adrenal, pyloric stomach, and skin.


GLOMUS-LIKE BODIES ON THE SUPERIOR MESENTERIC ARTERY. Minute endocrine-like structures have been detected where the cranial parasympathetic nerves cross a main vessel which carries blood to the heart, brain or arms. This suggests that their sites are fixed by function. These structures are the vago-tympanic and jugular glomera in the depths of the petrous bone near the jugular vein, carotid bodies, and aortic arch bodies, at crossings by the vagi. They have not been found in the human abdomen, although primary tumours with their endocrine-like structure do occur there.With the thought that these non-chromaffin glomus bodies may be the multiple miniature parasympathetic homologues of the adrenal medullae, a microscopic search was made for them at the root of the superior mesenteric artery. In 10 out of 15 aortas, glomera similar in appearance to the carotid body were found near the midline, about 1 cm. distal to the root of the artery and some 3 mm. external to its adventitia. In a single median section of celiac artery, one of these bodies was also found in a corresponding position. These form vital links for the concept that such bodies are parasympathetic endocrines. Because these bodies were discovered in two of the possible locations predictable for them in the human abdomen, the view that they comprise a definite system is strongly supported.


THE USE AND ABUSE OF TOPICAL STEROID THERAPY.


DISCOVERIES IN PATHOLOGY.

DISCOVERIES IN PATHOLOGY.


CATARACT SECTION ACROSS TEMPORARY STAINLESS-STEEL SUTURES. The purpose of the technique described was to combine the advantages of a cleanedged Graefe-knife incision with those of safety and near-perfect apposition offered by preplaced sutures: a preliminary to cataract extraction. Uncuttable preplaced 2-mm. stainless steel sutures were finally replaced after completion of the incision by attached braided silk for closure purposes.


CANCER CHEMOTHERAPY SUPPLEMENT XXXVI. A BIBLIOGRAPHY OF AGENTS. SUPPLEMENT, 1955-1959.


A RARE COMPLICATION OF COUMARINCONGENER ANTICOAGULANT THERAPY.


REHABILITATION OF PATIENTS WITH RHEUMATOID DISEASE.


UROLOGICAL PRACTICE AND THE BOWEL MOVEMENT.


PATHOGENESIS OF MALFORMATIONS.

PATHOGENESIS OF MALFORMATIONS.


HYPERTENSION DUE TO UNILATERAL RENAL ARTERY DISEASE. A CLINICAL PATHOLOGIC CONFERENCE.


THE ACTION OF OXYTETRACYCLINE ON R. PROWAZEKI IN LICE INOCULATED BY THE WEIGL METHOD.


EFFECTS OF METHENAMINE ON THE METABOLISM OF N1-(2,6-DIMETHYL-4-PYRIMIDINYL) SULFANILAMIDE (SULFISOMIDINE) BY THE RAT AND THE RABBIT.


CONSTANCY OF NUCLEAR DNA AND ACCURACY OF CYTOPHOTOMETRIC MEASUREMENT.


ENDOREDUPLICATION IN HUMAN FIBROBLAST CULTURES.


THE INDUCTION OF CHROMATID LESIONS BY CYTOSINE ARABINOSIDE IN POST-DNASYNTHETIC HUMAN LEUKOCYTES.


CHROMOSOMES OF THE GROUND SQUIRREL SPERMOPHILUS BELDINGI AND REPORT OF AN ABERRANT KARYOTYPE IN A PHENOTYPICALLY NORMAL FEMALE.


DIFFERENTIAL CONTRACTION OF LARGE AND SMALL CHROMOSOMES IN CULTURED LEUCOCYTS OF MAN.


MEIOTIC AND MITOTIC STUDIES OF A FAMILIAL RECIPROCAL TRANSLOCATION BETWEEN TWO AUTOSOMES OF GROUP 6-12.


EDUCATION TO COMBAT BLINDNESS.

EDUCATION TO COMBAT BLINDNESS.


EFFECT OF GONADAL HORMONES ON SUBMANDIBULAR GLAND AMYLASE ACTIVITY IN MALE AND FEMALE C57BL-6J-6J MICE.


A TRACER METHOD FOR DETERMINING THE CLEANING OF CONTACT LENSES.


INFLUENCE OF THE PRECORNEAL FILM ON THE APPLANOMETER IMPRINT.


A NOTE ON FORCED DUCTION TESTING AND AN AUXILIARY.


ON VERTIGO.

ON VERTIGO.


PREVENTION ON RECURRENCE OF PTERYGIUM.

PREVENTION ON RECURRENCE OF PTERYGIUM.


SURGICAL TREATMENT OF FACIAL PARALYSIS.

SURGICAL TREATMENT OF FACIAL PARALYSIS.


USEFULNESS OF MODERN DRUGS IN ALLERGIC OCULAR DISORDERS.


NASAL SINUS DISEASE: THE CONFUSED PROBLEM.


SHOULD THE INDICATIONS FOR TONSILLECTOMY BE REVISED?


OPHTHALMOLOGY: A VITAL SERVICE IN A MEDICAL CENTER.


APPLANOMETER TECHNIQUE.

APPLANOMETER TECHNIQUE.


AUDIOLOGY: ISO-AYE OR NO.

AUDIOLOGY: ISO-AYE OR NO.


THE ROLE OF HISTAMINE IN ALLERGIC DISORDERS.


CORNEAL INFECTIONS AND SUTURE REACTIONS AFTER CATARACT SURGERY.


SURGICAL FORMULAE FOR COMMON NASAL TIP PROBLEMS.


A SEMI-AUTOMATIC COMPUTER-MICROSCOPE FOR THE ANALYSIS OF NEURONAL MORPHOLOGY.


PRELIMINARY STUDY OF ILLINOIS DROWNINGS.


A COMPARISON OF THE IMMUNOLOGIC RESPONSES OF NORMAL AND  ATOPIC INDIVIDUALS TO PARENTERALLY INJECTED, ALUM PRECIPITATED PROTEIN ANTIGEN.


THE NATURE OF THE SKIN REACTION TO MOSQUITO BITES IN LABORATORY ANIMALS.


CAN THE SOCIAL SCIENCES IMPROVE THE NURSING SERVICES?


THE TIMING OF ORTHODONTIC TREATMENT.

THE TIMING OF ORTHODONTIC TREATMENT.


GLOSSODYNIA.

GLOSSODYNIA.


HEMATOLOGIC ANALYSIS AFTER GINGIVECTOMY.


PRELIMINARY REPORT OF HEALTH EVALUATION PROGRAM CONDUCTED BY ADA AT 1964 ANNUAL SESSION.


ENAMEL CARIES RESEARCH: 1962-1964.

ENAMEL CARIES RESEARCH: 1962-1964.


RADIATION BIOLOGY PERTINENT TO DENTISTRY.


RESEARCH IN BIOCHEMISTRY.

RESEARCH IN BIOCHEMISTRY.


RESEARCH IN ANATOMY, HISTOLOGY AND RELATED SCIENCES.


RESEARCH IN CLINICAL DENTISTRY--1964.

RESEARCH IN CLINICAL DENTISTRY--1964.


CHLORMADINONE, A POTENT SYNTHETIC ORAL PROGESTIN: EVALUATION OF 1002 CYCLES.


ORAL CANCER DETECTION.

ORAL CANCER DETECTION.


LIST OF GRADUATE TRAINING PROGRAMS SUPPORTED BY THE NATIONAL INSTITUTE OF DENTAL RESEARCH.


PUBLIC RELATIONS IN DENTISTRY. 3. WORKING WITH NEWS MEDIA.


CONTINUING EDUCATION OUTSIDE THE DENTAL SCHOOL SETTING.


REVISED PROCEDURE FOR LISTING CHARACTER OF PRACTICE IN THE AMERICAN DENTAL DIRECTORY.


DENTAL PREPAYMENT.

DENTAL PREPAYMENT.


CARTOON FILMS FOR TELEVISION.

CARTOON FILMS FOR TELEVISION.


PHASE OUT OF EDUCATIONAL WAIVERS FOR DENTAL ASSISTANT CERTIFICATION.


GAS-LIQUID CHROMATOGRAPHIC ANALYSIS OF MONOGLYCERIDES AS THEIR TRIMETHYLSILYL ETHER DERIVATIVES.


DETERMINATION OF POLAR LIPIDS: QUANTITATIVE COLUMN AND THIN-LAYER CHROMATOGRAPHY.


A REVIEW OF ANTIOXIDANT ANALYSIS IN FOOD PRODUCTS.


IMMUNIZATION OF SWINE.

IMMUNIZATION OF SWINE.


BIRTH AND DEATH STATISTICS ON PIGS OF PREWEANING AGE.


ABSCESSES OF SWINE.

ABSCESSES OF SWINE.


EPIZOOTIOLOGY OF EDEMA DISEASE IN SWINE.


EFFECT OF HOUSING ON ASCARIASIS IN GROWING-FINISHING SWINE.


THE PREVALENCE OF MICROSPORUM NANUM INFECTION IN SWINE.


TRICHINOSIS IN AN IOWA SWINE HERD.

TRICHINOSIS IN AN IOWA SWINE HERD.


SPECIALIZED PRODUCTION AND SWINE PRACTICE.


CLINICO-PATHOLOGIC CONFERENCE FROM THE SCHOOL OF VETERINARY MEDICINE UNIVERSITY OF PENNSYLVANIA.


SYNTHESIS OF RESERVE MATERIALS FOR ENDOGENOUS METABOLISM IN STREPTOCOCCUS FAECALIS. Forrest, W. W. (University of Adelaide, Adelaide, South Australia), and D. J. Walker. Synthesis of reserve materials for endogenous metabolism in Streptococcus faecalis. J. Bacteriol. 89:1448-1452. 1965.-The growth curve of Streptococcus faecalis in batch culture with limited energy source shows an initial portion of exponential growth where the growth yield coefficient Y(glucose) is 32, followed by linear growth where Y(glucose) is 21. Endogenous metabolism is correlated with maintenance of glycolytic activity, and there is a marked change in the glycolytic activity of cells harvested under these conditions; however, endogenous metabolism cannot be detected in either case by measurement of the adenosine triphosphate (ATP) pool in the organisms. Cells harvested after growth with excess energy source exhibit endogenous metabolism, which is correlated with a much higher concentration of ATP in the organisms than occurs in the cells grown with limited energy source.


METABOLIC PROPERTIES OF SOME L FORMS DERIVED FROM GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA. Weibull Claes (Central Bacteriological Laboratory of Stockholm City, Stockholm, Sweden), and Hans Gyllang. Metabolic properties of some L forms derived from gram-positive and gram-negative bacteria. J. Bacteriol. 89:1443-1447. 1965.-L forms of two gram-positive bacteria, a staphylococcus and a diphtheroid, were found to be devoid of catalase and cytochromes, whereas the normal bacteria from which these L forms were derived contained large amounts of these enzymes. On the other hand, L forms of a gram-negative bacterium, Proteus mirabilis, contained the same cytochromes as normal Proteus bacteria. (Previous investigations showed that normal cells and L forms of P. mirabilis contain approximately the same amounts of catalase.) The respiratory quotients (Q(O2)) of all L forms studied were much lower than those of the corresponding normal bacteria. The conversion of the normal organisms into L forms did not markedly affect their growth rate, measured as the time required for doubling the bacterial mass during the exponential-growth phase.


NATURE OF THE BACTERICIDAL ACTION OF ANTIMYCIN A FOR BACILLUS MEGATERIUM. Marquis, Robert E. (University of Rochester, Rochester, N.Y.). Nature of the bactericidal action of antimycin A for Bacillus megaterium. J. Bacteriol. 89:1453-1459. 1965.-Antimycin A, a fungicidal antibiotic which specifically inhibits metabolic reduction of cytochrome c, was found to be lethal for Bacillus megaterium. However, the bactericidal action was correlated with a capacity of antimycin to hinder plasma-membrane functions other than cytochrome-mediated respiration. With conditions under which oxygen consumption was not appreciably depressed, antimycin almost completely inhibited concentrative uptake of both alpha-aminoisobutyrate and alpha-methylglucoside, and also caused death of cells. When present in amounts greater than those required for killing or for inhibition of nutrilite uptake, antimycin also induced extensive loss of inorganic phosphate and other substances from whole cells, inhibited aerobic respiration, and acted as a lytic agent for isolated protoplasts. The lytic potency of antimycin was greater, on a molar basis, than that of digitonin, hexachlorophene, polymyxin B, and all but one of a number of test detergents. Protoplasts concentrated antimycin primarily in or on the plasma membrane, and the refractive index of isolated protoplast membranes rose sharply as a result of antimycin binding. In all, antimycin-induced lysis appeared not to include dissolution of the protoplast membrane similar to that produced by dodecyl sulfate. Rather, the lytic process seemed more akin to that induced by cationic detergents or by polymyxin.


SIGNIFICANCE OF SALMONELLAE ISOLATED FROM APPARENTLY HEALTHY MICE. Morello, Josephine A. (Boston University School of Medicine, Boston, Mass.), Teresa A. DiGenio, and Edgar E. Baker. Significance of salmonellae isolated from apparently healthy mice. J. Bacteriol. 89:1460-1464. 1965.-Three species of Salmonella were isolated from three groups of apparently healthy laboratory mice. The host-parasite relationship of one of these, a mutant S. typhimurium (lacks I and i antigens), was studied to determine the significance of these pathogens. Mice were fed undiluted broth cultures, and the infection was followed by means of fecal and organ cultures and a hemolytic serological test. Tissue invasion occurred during the early stages of the disease, but, within 1 week, the organism usually was localized in the intestinal tract. After 1 month, most of the mice had eliminated the organism completely. Antibody response to this organism was generally variable. Conditions of stress, including heat, cold, and cortisone administration, did not precipitate more severe disease in infected animals. The infection was maintained for longer periods of time in animals housed in groups than in those in individual cages. The presence of such salmonellae in laboratory animals appears to be of limited significance.


FLUORESCENT CELL-COUNTING NEUTRALIZATION TEST FOR PSITTACOSIS. Hahon, Nicholas (Fort Detrick, Frederick, Md.), and Kenneth O. Cooke. Fluorescent cell-counting neutralization test for psittacosis. J. Bacteriol. 89:1465-1471. 1965.-A sensitive, precise, and specific serological procedure, the fluorescent cell-counting neutralization test, was developed to detect and to measure quantitatively psittacosis serum-neutralizing antibodies within 24 hr. The test is based on the reduction of fluorescent cells in McCoy cell monolayers resulting from the neutralization of infective agent particles by specific antiserum. Small but significant rises in neutralizing titers were measured in serum specimens from monkeys previously exposed to the psittacosis agent and from humans with diagnoses of subclinical or established psittacosis infections.


INCREASED ACTIVITY OF TRYPTOPHAN BIOSYNTHETIC ENZYMES IN HISTIDINE MUTANTS OF NEUROSPORA CRASSA. Carsiotis, M. (University of Cincinnati College of Medicine, Cincinnati, Ohio), and Ann M. Lacy. Increased activity of tryptophan biosynthetic enzymes in histidine mutants of Neurospora crassa. J. Bacteriol. 89:1472-1477. 1965.-The activities of tryptophan synthetase and indoleglycerol phosphate synthetase, the last two enzymes in the tryptophan biosynthetic pathway, are elevated twofold or more in all histidine mutants of Neurospora crassa. The elevation occurs only when the mutants are grown in a histidine-limited medium. Several possible mechanisms for this elevation were disproved experimentally. The cause of the elevated enzyme activities remains unknown.


NITROGEN FIXATION BY MEMBERS OF THE TRIBE KLEBSIELLEAE. Mahl, M. C. (University of Wisconsin, Madison), P. W. Wilson, M. A. Fife, and W. H. Ewing. Nitrogen fixation by members of the tribe Klebsielleae. J. Bacteriol. 89:1482-1487. 1965.-Strains of species of the tribe Klebsielleae were tested for nitrogen fixation by inoculating actively growing cultures into side-arm flasks containing a medium with a growth-limiting quantity of combined nitrogen (25 mug of nitrogen per ml as ammonium sulfate). The flasks were evacuated, filled with pure N(2), sealed, and placed on a shaker at 30 C. Growth was followed by optical-density measurements; maximal growth was obtained in 9 to 10 hr. Yeast extract was then added as a source of amino acids to shorten the induction time for the nitrogen-fixing enzymes. Fixation was determined either by estimating total nitrogen with a semimicro Kjeldahl technique or by exposing 20- to 22-hr-old samples to an atmosphere of N(2) (15) and helium for 5 hr and then analyzing the digested sample for N(15) in a mass spectrometer. None of the 22 strains of the two Enterobacter (formerly Aerobacter) species fixed nitrogen; neither did any of eight strains of Serratia species that were tested. Of 31 strains of Klebsiella pneumoniae, 13 incorporated atmospheric nitrogen. Net nitrogen fixed ranged from 17 to 65 mug/ml. It is concluded that these facultative anaerobic, gram-negative, nitrogen-fixing rods should be placed in the genus Klebsiella pneumoniae. The nitrogen-fixing organism tentatively classified as Achromobacter N-4 should also be changed to K. pneumoniae strain N-4, because it has been found to be an anaerogenic strain of K. pneumoniae.


CHARACTERIZATION OF CONJUGATION FACTORS IN ESCHERICHIA COLI CELL WALLS. I. INHIBITION OF RECOMBINATION BY CELL WALLS AND CELL EXTRACTS. Lancaster, John H. (University of Texas, Austin), E. P. Goldschmidt, and Orville Wyss. Characterization of conjugation factors in Escherichia coli cell walls. I. Inhibition of recombination by cell walls and cell extracts. J. Bacteriol. 89:1478-1481. 1965.-An assay procedure was devised to determine quantitatively the interference with conjugation of cell-wall fragments from both male and female strains of Escherichia coli. The fertility of the donor is reflected in the assay. Phenol extracts from the cell walls were active, and chemical analysis suggested that the activity resided in the lipopolysaccharide fraction.


LIPIDS OF DEBARYOMYCES HANSENII.

LIPIDS OF DEBARYOMYCES HANSENII. Merdinger, Emanuel (Roosevelt University, Chicago, Ill.), and Edward M. Devine, Jr. Lipids of Debaryomyces hansenii. J. Bacteriol. 89:1488-1493. 1965.-The separation of neutral lipids and phospholipids from the lipid extract of Debaryomyces hansenii NRRL Y-1448 was accomplished by using a single column packed with silicic acid. The neutral lipids comprised 67%, and the phospholipids 33%, of the total lipid extract. Qualitative and quantitative characterization of the lipids was effected by various analytical procedures. Gas chromatography of the fatty acid methyl esters showed 11 acids, of which 59.7% were unsaturated. The most abundant among the unsaturated acids was the monounsaturated C18 acid (50.1%). Among the saturated acids, palmitic acid (23.5%) prevailed. Ratios of fatty acid to glycerol, phosphorus to glycerol, and phosphorus to fatty acid were ascertained for combined cuts from the neutral lipids and the phospholipids. The presence of ergosterol, stigmasterol, and an unidentified sterol was established by gas chromatography. Also present were saturated hydrocarbons containing 16 to 39 carbon atoms, C22 being the most prevalent.


ENHANCEMENT BY ADENINE OF THE INHIBITION OF SALMONELLA TYPHIMURIUM BY ETHIONINE. Smith, Robert C. (Auburn University, Auburn. Ala.), and W. D. Salmon. Enhancement by adenine of the inhibition of Salmonella typhimurium by ethionine. J. Bacteriol. 89:1494-1498. 1965.-The inhibition by ethionine of the growth of Salmonella typhimurium was increased by adenine and several other purines. This effect was counteracted by the addition of methionine to the cultures. There was no preferential inhibition of nucleic acid or protein synthesis by adenine plus ethionine. Adenine stimulated the uptake of radioactive ethionine by the cells. Adenine may produce the effects observed by increasing the rate at which ethionine enters the cell and reaches its primary site of antibacterial action.


COMPARISION OF SOLUBLE REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE OXIDASES FROM CELLS AND SPORES OF CLOSTRIDIUM BOTULINUM. Green, J. H. (Michigan State University, East Lansing), and H. L. Sadoff. Comparison of soluble reduced nicotinamide adenine dinucleotide oxidases from cells and spores of Clostridium botulinum. J. Bacteriol. 89:1499-1505. 1965.-The properties of purified reduced nicotinamide adenine dinucleotide (NADH(2)) oxidases from cells and spores of Clostridium botulinum 62-A have been studied to determine whether they are the same or different proteins. The spore NADH(2) oxidase was very heat-stable, whereas the vegetative enzyme was readily denatured at 70 C. The spore oxidase exhibited less affinity for the substrate than did the vegetative protein, but possessed a tightly bound cofactor. Atabrine was a noncompetitive inhibitor for both enzymes, but was less inhibitory to the spore NADH(2) oxidase. The enzymes could be separated from each other by gel filtration or chromatography on a diethylaminoethyl-cellulose column. The molecular weight of the spore oxidase was estimated to be 200,000 or greater, whereas that of the vegetative enzyme was 100,000 or less. Neither NADH(2) oxidase would cross-react with its heterologous antibody in a precipitation reaction. The conclusion drawn from this investigation is that the two NADH(2) oxidases are distinctly different proteins.


CHANGES IN THE NUCLEOTIDE POLL OF BACILLUS LICHENIFORMIS DURING SPORULATION. Leitzmann, Claus (University of Minnesota, Minneapolis), and Robert W. Bernlohr. Changes in the nucleotide pool of Bacillus licheniformis during sporulation. J. Bacteriol. 89:1506-1510. 1965.-An analysis of the amount of acid-soluble nucleotides in Bacillus licheniformis cells showed a 75% increase during presporulation over that in log-phase cells. Cultures in which presporulation was inhibited by actinomycin D showed a decrease in acid-soluble nucleotides during the same time interval. A separation and quantitative determination of the nucleotides in the pool revealed that the relative proportion of each nucleotide remained fairly constant during presporulation. The detection of an intracellular ribonuclease activity and a decrease of the total nucleic acid concentration in the cells suggest that the increased pool arises from polymer breakdown. The effect of actinomycin D on sporulation was examined on both a quantitative and a temporal basis. The data indicate that messenger ribonucleic acid is essential for the completion of the sporulation process and must be resynthesized constantly.


PHOTOREVERSIBLE ULTRAVIOLET ENHANCEMENT OF INFECTIVITY IN AGROBACTERIUM TUMEFACIENS. Heberlein, Gary T. (Northwestern University, Evanston, Ill.), and James A. Lippincott. Photoreversible ultraviolet enhancement of infectivity in Agrobacterium tumefaciens. J. Bacteriol. 89:1511-1514. 1965.-Irradiation of a virulent strain of Agrobacterium tumefaciens with short-wavelength ultraviolet light, which reduces viability 50 to 90%, increases its infectivity as measured by the number of tumors initiated per viable bacterial cell on primary pinto bean leaves. A dark treatment of 1.5 to 2 hr between irradiation and inoculation results in a further increase in specific infectivity of as much as fourfold. This increase in infectivity is inhibited by white fluorescent light and light of 402 mmu, but only slightly by 549- or 619-mmu light. These results imply that some change in the deoxyribonucleic acid of the bacterium is responsible for this effect.


DEGRADATION AND UTILIZATION OF ISOLATED HEMICELLULOSE BY PURE CULTURES OF CELLULOLYTIC RUMEN BACTERIA. Dehority, B. A. (Ohio Agricultural Experiment Station, Wooster). Degradation and utilization of isolated hemicellulose by pure cultures of cellulolytic rumen bacteria. J. Bacteriol. 89:1515-1520. 1965.-Hemicelluloses isolated from flax, corn hulls, alfalfa, oat hulls, and fescue grass were used as sole energy sources to study the ability of pure cultures of cellulolytic rumen bacteria to degrade and utilize these materials. From a total of eight bacterial strains tested (three strains of Bacteroides succinogenes, four strains of Ruminococcus flavefaciens, and one strain of Ruminococcus albus), only three strains of ruminococci were able to utilize the hemicelluloses for growth. Hemicellulose fermentation mixtures were analyzed for total pentose, residual hemicellulose (pentose precipitated in 80% ethyl alcohol), and ethyl alcohol-soluble pentose. The three strains of ruminococci were able to partially utilize the different hemicelluloses as energy sources, as determined by total pentose loss, and they were capable of almost complete degradation of the original hemicellulose from an ethyl alcohol-insoluble to ethyl alcohol-soluble form. The extent of both degradation and utilization varied markedly between the three strains and different substrates. Tests on the other strains indicated that no growth, production of organic acid end products, or appreciable loss of total pentose had occurred. However, analysis of the culture medium for residual hemicellulose indicated that these strains were able to extensively degrade the original hemicelluloses to an ethyl alcohol-soluble form. Marked differences were observed among strains and hemicelluloses in the amount of hemicellulose degraded. Of the different hemicelluloses, corn-hull hemicellulose was the most resistant to degradation and utilization by the cellulolytic rumen bacteria.


AMINO ACID UTILIZATION BY ALCALIGENES VISCOLACTIS FOR GROWTH AND SLIME PRODUCTION. Punch, J. D. (University of Minnesota, St. Paul), J. C. Olson, Jr., and J. V. Scaletti. Amino acid utilization by Alcaligenes viscolactis for growth and slime production. J. Bacteriol. 89:1521-1525. 1965.-The ability of Alcaligenes viscolactis to utilize amino acids in a basal salts solution (K(2)HPO(4), KH(2)PO(4), MgSO(4), MnSO(4), FeSO(4), NaCl) was studied. Of 27 amino acids, only l-asparagine, l-glutamic acid, l-aspartic acid, l-glutamine, l-proline, and l-tyrosine supported growth sufficient to give a viscous supernatant solution. l-Proline and l-tyrosine, singly or combined, fulfilled the carbon, nitrogen, and energy requirements for growth and slime production. None of eight inorganic nitrogenous compounds supported growth with lactose as the carbon source. The addition of l-asparagine, l-aspartic acid, or l-glutamine to l-tyrosine or l-proline, singly or combined, did not increase growth or slime production, indicating no nutritional interactions among these amino acids. Neither lactose nor glucose was found to be required or utilized by A. viscolactis in a medium containing basal salts, l-proline, l-tyrosine, and lactose or glucose. This was established by the fact that total carbohydrate and total reducing activity remained constant during growth and slime production.


CYTOCHEMICAL AND ELECTRON MICROSCOPICAL OBSERVATIONS ON THE PRESENCE AND ORIGIN OF ADENOSINE TRIPHOSPHATASE-LIKE ACTIVITY AT THE SURFACE OF TWO MYXOVIRUSES. Dawson, C. R. (The Middlesex Hospital Medical School, London, England), M. A. Epstein, and K. Hummeler. Cytochemical and electron microscopical observations on the presence and origin of adenosine triphosphatase-like activity at the surface of two myxoviruses. J. Bacteriol. 89:1526-1532. 1965.-HeLa cells infected with either fowl plague virus (FPV) or Newcastle disease virus (NDV) were examined in thin sections by electron microscopy. Preparations were studied both after direct fixation and embedding and after the application of cytochemical staining for enzymes splitting adenosine triphosphate. Viral particles were identified by their size and characteristic structure, and were found to form at the cell surface by budding out through structurally altered plasmalemma. After cytochemical staining for adenosine triphosphatase activity, extracellular FPV or NDV particles lying close against cell membranes with enzyme activity likewise carried this function, whereas those particles which were associated with cell surfaces without reaction product were themselves free from it. This correspondence between enzyme function in cell membranes and the outer viral membranes of newly formed particles adjacent to them indicates that surface enzymatic capability of the host cell survives even when the cell membrane undergoes morphological and antigenic alteration into myxovirus outer membrane.


DEVELOPMENT OF RESISTANCE TO POLYENE ANTIBIOTICS IN CANDIDA ALBICANS. Hebeka, Elias K. (Rutgers, The State University, New Brunswick, N.J.), and Morris Solotorovsky. Development of resistance to polyene antibiotics in Candida albicans. J. Bacteriol. 89:1533-1539. 1965.-Strains of Candida albicans resistant to the polyenes candidin and amphotericin B, but not to nystatin, were developed by sub-culturing the organism in gradually increasing concentrations of the antibiotic in broth on a shaker, or by repeated transfer on gradient plates. Demonstration of resistance on solid media was best observed when a purified agar, Ionagar no. 2 (Oxoid), was used in preparing the medium. Strains that were 150-fold resistant to candidin, and 4-, 16-, 45-, and 60-fold resistant to amphotericin B were developed. The degree of resistance depended on the strain, the type of medium, and, most importantly, on the antibiotic used. The polyenes candidin, amphotericin B, nystatin, and fungimycin and the nonpolyenes griseofulvin and eulicin were used to extend the scope of study of cross-resistance. Cells rendered resistant to candidin were also resistant to amphotericin B, but not to nystatin, fungimycin, or griseofulvin. Cells rendered resistant to amphotericin B showed cross-resistance to candidin, but not to nystatin, fungimycin, or griseofulvin. Candidinor amphotericin B-resistant strains were more sensitive to eulicin than their parent strains. Increased resistance to candidin or amphotericin B was accompanied by a decrease in virulence for mice, the rate of growth, the ability to reduce bismuth sulfite, and by an increased tendency for filamentation. No change in the ability to form chlamydospores was noticed.