The histochemical differentiation of types of cholinesterase and their distributions in the tissues of the cat.


Biochemical and physiological differentiation during morphogenesis. XI. The appearance of muscular responses to electrical stimulation of the cerebral cortex of the developing guinea pig.


Experimental transposition of the pulmonary veins.


Comparative immunology of wild and domesticated rats in light of hypersensitivity diseases in man.


Studies of regeneration of the sympathetic fibers in peripheral nerves.


Treatment of neuronitis with BAL.

Treatment of neuronitis with BAL.


The mechanism of coup-contrecoup injuries of the brain; a critical review of recent experimental studies in the light of clinical observations.


Paget's disease and intracranial tumor; association of an astrocytoma of right temporal lobe with osteitis deformans.


Traumatic pneumocephalus; a brief review with report of case.


Orientation in the medical library.

Orientation in the medical library.


Orientation in the medical library; training the new librarian assigned to medical library.


National medical indexes.

National medical indexes.


Planning the biomedical library at U.C.L.A.


The library of the Medical Society of South Carolina.


Punched cards for circulation records.

Punched cards for circulation records.


Discontinuance of index-catalogue.

Discontinuance of index-catalogue.


On correcting errors in medical journals.


Public health aspects in the development of atomic energy.


The borderland of embryology and pathology.


Oxygen therapy in acute rheumatic carditis in children.


Inhalational therapy in acute respiratory infections, measles, whooping cough and pneumonia.


Oxygen as a supportive therapy in fetal anoxia.


The use of oxygen in comatose states.

The use of oxygen in comatose states.


Outline of the use of respirators and of oxygen in poliomyelitis.


The experimental analysis of virulence of tubercle bacilli.


A component of tubercle bacilli concerned with their virulence.


Application of virulence studies to the problems of BCG immunization.


Certain aspects of benign and malignant gastric ulcer.


Anti-microbial therapy in pulmonary tuberculosis: medical aspects.


Modern gastro-duodenal surgery.

Modern gastro-duodenal surgery.


Virus infections of the nervous system.

Virus infections of the nervous system.


The value of the bone puncture for obtaining marrow as a diagnostic procedure.


Antihistaminic agents-studies of their metabolism by means of quantitative analytical methods.


A heat resistant mutant of bacterial virus T5.


Modification of the course of a viral pneumonia in mice.


Further experiments with Columbia SK murine poliomyelitis virus.


LIFE sketch of Dr. Sundari Mohan Das.

LIFE sketch of Dr. Sundari Mohan Das.


Antibiotics in tuberculosis.

Antibiotics in tuberculosis.


Laboratory diagnosis of fevers in the tropics.


Dystrophia myotonica.

Dystrophia myotonica.


A case of recurrent eclampsia.

A case of recurrent eclampsia.


Psychoneurosis in ophthalmic practice.

Psychoneurosis in ophthalmic practice.


Intragastric drip therapy of peptic ulcer.


What's new in thyroid surgery.

What's new in thyroid surgery.


What's new in cardiovascular surgery.

What's new in cardiovascular surgery. Advances in the treatment of congenital cardiovascular lesions have led to a renewed interest in the treatment of acquired heart disease. Although this field could best be served by the perfection of the extracorporal heart, such devices are as yet not ready for human application. Meanwhile, various approaches through the ventricles and left atrium have been developed to treat valvular stenosis. Refinements in diagnostic tests and in methods of physiological investigation are of great aid in the proper evaluation of patients.


The background of delinquency.

The background of delinquency.


What's new in isotopes, 1950.

What's new in isotopes, 1950.


Leading causes of childhood death.

Leading causes of childhood death. The over-all rates of death in childhood decreased five to ten fold during the first half of the century, with the greatest drop occurring in deaths due to infections. The death rate due to accidents has shown a relatively slight decrease; hence, accidents are now the leading cause of childhood death, and in California account for 32 per cent of the deaths in the group 1 to 15 years of age. In California, and among certain insured groups of children, cancer is the leading or second leading cause of death due to disease. There is indication that the incidence of leukemia is increasing in early childhood and in the older age groups.Accidents, the leading cause of childhood death, do not happen; they are caused, and so can be prevented. The medical profession should concern itself much more actively in the field of accident prevention.


Chronic ulcerative colitis--psychosomatic factors. In six cases of idiopathic ulcerative colitis here reported, close correlation with emotional stress was shown. Psychosomatic relationship seemed definite. Experience with 85 patients with ulcerative colitis has led to the suggestion that emotional stress may be causative or a predisposing factor in some, perhaps all, such cases.


Diagnosis and differential diagnosis of poliomyelitis; the management of patients in the hospital admitting room. Because of the great variety of early symptoms of poliomyelitis and their similarity to the symptoms of a number of other diseases, in times of epidemic many patients are admitted to hospital on suspicion of poliomyelitis. At such times the prime purpose of the hospital admitting room staff is to distinguish between patients with poliomyelitis (or other diseases requiring immediate treatment) and those who may be referred into other channels. This presentation (1) points out the superficial similarities of the clinically observable signs and symptoms and of laboratory data in poliomyelitis and in other diseases, and (2) discusses the more occult dissimilarities which aid in differentiation.


Endemism of Coccidioidomycosis in the Paraguayan Chaco. Skin testing of 541 men with coccidioidin was carried out in an investigation of endemism of coccidiodomycosis in the Paraguayan Chaco. In two areas where the climate is hot, dry and windy, positive reactions developed in a considerable number of the employees of an oil company who were of various racial origins, as well as among native Indians. In a third area, where rain is more plentiful and vegetation lush, only 2 per cent of 250 Indians tested had positive reaction to coccidioidin.


Cytology of the postnasal drip.

Cytology of the postnasal drip. About half of a series of 100 consecutive patients with disturbances of the eyes, ears, nose or throat complained of postnasal drip. When smears of the mucous discharge were examined it was found that in about a third of the cases in which there was complaint of drip, neither eosinophils nor neutrophils could be demonstrated. This indicates that causes of the drip other than allergic disease and infection must be considered.Cytologic examination of the postnasal drip showed that about one-third of the patients with nasal disease or histories positive for allergic reaction had nasal eosinophilia. Nasal eosinophilia was noted occasionally in patients with normal-appearing nasal structures and in patients with no history of allergic disease.


Anuria and oliguria; treatment by conservative means, case report, with determination of blood volume and Na24 space.


Allergic sinusitis treated as a deficiency disease.


Barnyard fowl as a source of human ornithosis.


Antabus and the metabolism of alcohol.

Antabus and the metabolism of alcohol. Antabus does not alter the rate of alcohol metabolism in dogs. It interferes with the metabolism of acetaldehyde, so that the ordinarily prompt removal of this substance from the tissues as it is produced in the metabolism of alcohol does not take place. It seems reasonable to assume that it is this accumulation of acetaldehyde in the tissues in abnormally high concentrations that is responsible for the unpleasant symptoms following the taking of alcohol by a patient receiving antabus.


The use of antabus in the therapy of alcoholic patients. Preliminary studies on the effects of antabus (tetraethylthiuram disulfide) in the therapy of alcoholic patients indicate that it is very valuable in providing a "chemical foundation" for sobriety, even in those with a severe, long term drinking problem. In the first 30 patients treated, a favorable degree of control of the alcoholism has been effected in approximately 80 per cent. When taken regularly the drug maintains in the patient a very high degree of sensitivity to alcohol, quickly producing a number of very distressing bodily reactions whenever even very small amounts of spirits are ingested. Because of its potential dangers, antabus should be used only after thorough clinical and laboratory studies in properly staffed institutions. It is contraindicated in individuals with existing major psychosis or drug addiction and must be used only with caution in patients with diabetes mellitus, cardiovascular disease, goiter, pregnancy, epilepsy, asthma, and hepatic disease. Antabus therapy should be considered only one aspect of the total treatment program for the alcoholic patient.


Antabus in the treatment of alcoholism in a private general hospital. In 35 consecutive cases in which patients were admitted to a private hospital for alcoholism, antabus was contraindicated for eight patients and administered to 27. Sixteen patients, followed three to nine months, cooperated fully with treatment and did not return to use of alcohol. In four cases there was at least one episode of drinking, but the patients continued to cooperate with treatment and attained partial success. In seven cases, including three in which antabus was stopped because of organic disease, treatment was unsuccessful. Insufficient insight and lack of family cooperation accounted for four failures. The presence of cardiovascular or hepatic diseases contraindicates antabus. As the test of reaction to alcohol after antabus has been given is hazardous, continuous supervision by nurse and physician throughout the test reaction is mandatory. Sustained results depend upon psychotherapy, family cooperation, careful follow-up, and control of side-reactions to the drug. Antabus as an antagonist to alcohol is not safe enough to permit general use of the drug.


A survey of the results of treatment of gastric cancer in San Francisco. A survey was made of all patients treated for gastric cancer on the clinic services of the Stanford University Hospital during the 30-year period 1919 to 1948. During the last decade of the survey there were impressive gains in the surgical treatment of this disease. It was possible from 1944 to 1948 to do a gastric resection on half the patients seen with cancer of the stomach. Also, there was a pronounced decrease in resection mortality so that from 1939 to 1948 the mortality rate for subtotal gastrectomy for cancer was 3 per cent. The over-all five-year survival rate was discouragingly low-4.6 per cent. On the other hand, 23 per cent of those surviving gastric resection lived for five years.A survey of the management of carcinoma of the stomach from 1939 to 1948 was made in 11 general hospitals in San Francisco. A wide range of resectability and resection mortality rates was observed. The cases from these hospitals were combined with those from Stanford for the same period to form a composite group of 1,128 patients. Analysis of this group of cases from 12 representative hospitals in San Francisco showed encouraging trends toward higher resectability rates with a lower resection mortality.


Carcinoma of the esophagus and gastric cardia, with special reference to treatment. During the last five years the thoracic and abdominothoracic approaches in esophageal and gastric surgery have become established. With improvements in surgical and anesthetic technique mortality rates have declined. Preoperative and postoperative care are of great importance.


Gastric resection; preoperative and postoperative care. Perhaps in no other field of surgery does attention to minute detail play so important a role in determining success as it does in gastric operations. As surgery of the stomach develops toward even greater security and favorable results can be expected with greater confidence, the several aspects of preoperative and postoperative care hitherto regarded as secondary demand closer consideration.


Dicumarol and quinidine in the ambulatory treatment of chronic auricular fibrillation. Thirty-three patients with chronic auricular fibrillation were treated with digitalis and quinidine and in addition were given Dicumarol(R) to reduce the risk of embolism. In 21 of the patients the fibrillation was caused by rheumatic heart disease, and in 12 by arteriosclerosis or hypertension. Normal sinus rhythm was restored in 55 per cent of the 33 patients, in 67 per cent of those with arteriosclerosis or hypertension, and in 45 per cent of those with rheumatic heart disease. Embolism did not occur.


The administration of anticoagulants.

The administration of anticoagulants. Heparin is administered parenterally. Its therapeutic effect is measured by the clotting time of the whole blood, determined by the method of Lee and White. An excessive anticoagulant effect is controlled by the administration of specific antagonists, toluidine blue or protamine sulfate. Dicumarol* is admintered orally in amounts sufficient to reduce the prothrombin activity of the plasma to between 10 and 30 per cent of normal. The prothrombin time, which represents such a reduction in prothrombin activity, will vary according to the method by which the determination is performed, the thromboplastin used, and the technique followed. Excessive prolongation of the prothrombin time is antagonized by the administration of vitamin K in large doses. Long-term therapy with Dicumarol is sufficiently hazardous to require considerable experience on the part of the physician. Where an immediate anticoagulant effect is necessary, yet prolonged administration anticipated, combined therapy with both heparin and Dicumarol may be used until the prothrombin time is prolonged satisfactorily, whereupon heparin may be discontinued.


A simple electrosurgical treatment of rhinophyma.


Amebic abscess of the liver.

Amebic abscess of the liver. In a review of the records in 50 cases of amebic abscess of the liver observed in the Canal Zone between 1920 and 1945 the following features were noted:Incidence was preponderantly in males and highest in persons between the ages of 20 and 40. None of the patients was under 21 years of age. There was a great variety of complaints at the time of admission to hospital. The most common was pain in the right upper quadrant of the abdomen. Demonstration of either elevated or fixed diaphragm by x-ray film and fluoroscopic examination was useful in diagnosis in a number of cases, but absence of such findings did not rule out abscess of the liver. In some cases there was history of previous dysentery with blood in the stools.One or another of three operative procedures was used for drainage of abscesses in 39 patients. Of the 39, six died; in five of the six, multiple abscesses were present. Emetine hydrochloride was given to all patients.


Adrenocortical tumors.

Adrenocortical tumors. Hormonally active tumors of the adrenal cortex are either benign adenomas or adenocarcinomas. They may be located within the adrenal gland or as adrenal rests along the Wolffian tract. Hyperplastic cortical tissue without actual neoplastic formation is also capable of elaborating excessive cortical secretions.AT THE PRESENT STATE OF KNOWLEDGE, ANY ONE OR A COMBINATION OF THE FOLLOWING COMPOUNDS MAY BE ELABORATED IN A GIVEN CASE: the electrolytic, glucogenic, androgenic, or estrogenic corticosteroids. Whether or not Cushing's syndrome is primarily pituitary or adrenal in origin is still a matter of conjecture.


Rehabilitation of patients with hemiplegia. Many patients with hemiplegia can be rehabilitated. Physiological reflexes may be used in attempting to establish patterns of motion and are of definite aid in overcoming contractures. Physical and occupational therapy is of value.


Toxicology of organic phosphate insecticides. The development of effective new insecticides has created potential industrial health hazards to people engaged in their manufacture and application, as well as to those with casual exposures. A group of these insecticides known as the organic phosphates is extremely toxic, destroying the enzyme cholinesterase and exerting a cholinergic action on the mammalian animal. A discussion of the origin, chemistry, and pharmacology of these compounds, along with a description of symptoms, diagnosis and treatment of poisoning is presented. Methods of prevention of poisoning and control measures for the safe use of these compounds are described.


Homologous serum hepatitis following operation on the biliary tract; report of 3 cases.


Electrocardiogram immediately before and after septal infarction; report of a case.


Tuberculous fistula in a postpartum uterus; report of a case.


Medical technicians: the present need and training in California.


Training of hospital administrators; existing facilities here and elsewhere.


The Princess Elizabeth Hospital.

The Princess Elizabeth Hospital.


Hospitals and the press.

Hospitals and the press.


Hospitals and the radio.

Hospitals and the radio.


HANDSOME structure to replace present Bowmanville Hospital.


BEAUTY service as a therapy.

BEAUTY service as a therapy.


Evaluating the status of the hospital orderly.


MEDICAL services in Newfoundland.

MEDICAL services in Newfoundland.


Pursuing accuracy and completeness in medical records.


MARITIME Hospital Convention.

MARITIME Hospital Convention.


APPETIZING recipes.

APPETIZING recipes.


Algal poisoning in Ontario.

Algal poisoning in Ontario.


Liver rot (fascioloidiasis) in ruminants.


Vaccination of sexually mature cows with Brucella abortus strain 19 vaccine.


Listeria monocytogenes in lemming.

Listeria monocytogenes in lemming.


Rupture of the gastrocnemius tendon in chickens.


Some important swine diseases.

Some important swine diseases.


Canine giardiasis and its treatment with atebrin.


Report of a Salmonella (paratyphoid) survey in Alberta.


Field treatment of a fracture in a heifer.


Fish-borne and type E botulism: two cases due to home-pickled herring.


Cancer mortality trends in different countries.


Control of pollution by federal authorities.


Plague.

Plague.


Poliomyelitis virus in urban sewage; an examination for its presence over a period of 12 months.


Sanitation in a flooded area.

Sanitation in a flooded area.


The medical officer of health in Great Britain.


The relationship of the census to public health.


Eugeria.

Eugeria.


Signs of malnutrition in Canada.

Signs of malnutrition in Canada.


Melanotic sarcoma.

Melanotic sarcoma.


The value of sputum examination in diagnosis of cancer of the lung.


Administrative medicine.

Administrative medicine.


Some aspects of surgery of the stomach.

Some aspects of surgery of the stomach.


Face and brow presentations.

Face and brow presentations.


Malignant mischief.

Malignant mischief.


Tick paralysis.

Tick paralysis.


Posture in lung surgery.

Posture in lung surgery.


The plication operation in the treatment of peritoneal adhesions.


The present status of orbital implants.

The present status of orbital implants.


Cysts of the lung and of the mediastinum.


Consideration of the requirements and training of a plastic surgeon.


Partial cholecystectomy.

Partial cholecystectomy.


The plasma concentration of quinidine after oral administration and its effect on auricular fibrillation.


The treatment of pain and "spasm" in poliomyelitis with "priscoline".


Rheumatic pancarditis treated with cortisone.


Synchronous lymphatic leukaemia bronchogenic carcinoma and hypernephroma.


A case of exomphalos.

A case of exomphalos.


Latent silicosis.

Latent silicosis.


Tuberculous pericarditis treated with streptomycin.


Primary splenic neutropenia with rheumatoid arthritis. (Felty's syndrome).


An outline of iron metabolism.

An outline of iron metabolism.


Prostigmine vaginal suppositories in delayed menstruation.


A new approach to the treatment of foot-drop.


Distribution of medical service.

Distribution of medical service.


Some observations on genius.

Some observations on genius.


Unskilful surgery.

Unskilful surgery.


JOHN of Arderne and cancer of the rectum.


Factors contributing to delay by patients in seeking medical care.


The relation between the toxic action and the tumor-inhibiting power of some drugs.


The metabolism of radioactive dibromoestrone in man.


Hepatic dysfunction in candidates for abdominal surgery, especially in patients with cancer.


Reoperation following pancreato-duodenectomy.


Roentgenotherapeutic changes in the small intestine; surgical aspects.


The spread of carcinoma of the colon and rectum.


Mesenchymoma of the mesentery.

Mesenchymoma of the mesentery.


Epidermoid carcinoma of the hand.

Epidermoid carcinoma of the hand.


Pituitary chromophobe tumors of the nasal cavity.


Nonchromaffin paraganglioma of ganglion nodosum, carotid body, and aortic-arch bodies.


The modification of resistance to ionizing radiation by humoral agents.


Detection of cerebral tumors by ultrasonic pulses; pilot studies on postmortem material.


The significance of low calcium and high potassium content in neoplastic tissue.


Tumor-host studies. II. Increased concentration of tagged iodotyrosines in the gastrointestinal tract of rats bearing tumors.


Studies on the influence of sex hormones on successful heterologous transplantation of human bronchogenic carcinoma.


Quantitative differential fixation of sulfate by tissues maintained in vitro; sulfate fixation as a function of age for embryonic tissues.


Tumors in the invertebrates: a review.

Tumors in the invertebrates: a review.


This business of cancer research.

This business of cancer research.


Response of a transplantable lymphosarcoma to colchicine.


Studies in Hodgkin's syndrome. X. The morphology and growth patterns of explant cells cultivated in vitro.


The changes in the mitotic mechanism of human cancer cells.


The virus-induced rabbit papilloma-to-carcinoma sequence. II. Carcinomas in the natural host, the cottontail rabbit.


Serum polysaccharide levels in rats bearing the Walker 256 tumor.


The effect of the proportion of dietary fat on the rate of formation of mammary carcinoma in mice.


The effect of added dietary tryptophane on the occurrence of 2-acetylaminofluorene-induced liver and bladder cancer in rats.


Mechanism of ventricular fibrillation.

Mechanism of ventricular fibrillation.


The pathogenesis of angina pectoris and some clinical implications.


NEW isotope laboratory.

NEW isotope laboratory.


An integrating circuit for measurement of the areas of the waves in the electrocardiogram.


Intracardiac and intravascular potentials resulting from electrical activity of the normal human heart.


Peri-infarction block; electrocardiographic abnormality occasionally resembling bundle branch block and local ventricular block of other types.


Excitation of human auricular muscle and the significance of the intrinsicoid deflection of the auricular electrocardiogram.


Studies in intracardiac electrography in man; IV. the potential variations in the coronary venous.


QRS-T patterns in multiple precordial leads that may be mistaken for myocardial infarction III. bundle branch block.


Other QRS-T patterns that may be mistaken for myocardial infarction; IV. alterations in blood potassium; myocardial ischemia; subepicardial myocarditis; distortion associated with arrhythmias.


Clinical electrocardiography--its present position and possible potentialities.


Standardizing factors in electrocardiography.


The validity of the equilateral tetrahedron as a spatial reference system.


An approximate derivation for stereoscopic vectorcardiograms with equilateral tetrahedron.


Comparison of heart vectors calculated with different systems of leads.


Chronic pericarditis with effusion.

Chronic pericarditis with effusion.


Blood lipids and human atherosclerosis.

Blood lipids and human atherosclerosis.


Impending hemorrhagic shock and the course of events following administration of dibenamine.


Changes in the ballistocardiogram after exercise in normal and abnormal subjects.


The electrokymography; studies in recording fidelity.


The effects of intravenous aminophylline upon the coronary blood-oxygen exchange.


Blood vessels of the skin in chronic venous insufficiency.


The interrelationships of serum cholesterol, cholesterol esters and phospholipids in health and in coronary artery disease.


Effect of potassium and of desoxycorticosterone acetate in acute heart injury in the rat.


Electrical effects of stimulating the endocardial surface of the right ventricle of the dog.


Ventricular tachycardia during cardiac catheterization of patient with Wolff-Parkinson-White syndrome; report of a case showing effects of atropine sulfate.


Arrhythmias during intracardiac catheterization.


Electrokymographic studies of the normal cardiac cycle.


Abdominal aortic aneurysm; a study of one hundred and two cases.


Sodium gentisate in the treatment of acute rheumatic fever.


Studies on blood coagulation and the effect of digitalis.


The use of digitalis in spite of the presence of ventricular tachycardia.


Liver function tests in chronic congestive heart failure.


Pericardial effusion mistaken for cardiac enlargement in severe anemia.


Lodging of an embolus in a patent foramen ovale.


The present status of pertussis immunization; progress report.


The use of chloramphenicol (chloromycetin) in the treatment of infections of the urinary tract in childhood; special report.


Primary encephalitis of undetermined virus etiology.


Cyanosis in an infant with dextrocardia, situs inversus, and tricuspid atresia.


CLINICO-pathological conference; atrophy of the left kidney and cystic degeneration of right kidney with bilateral hydroureteronephrosis due to obstruction by a congenital valve in the prostatic urethra.


Breast cancer.

Breast cancer.


The role of potassium in medical therapy.


Dysphagia and dysphonia as symptoms of cancer.


A review of wound disruptions.

A review of wound disruptions.


Torsion of the gallbladder.

Torsion of the gallbladder.


Antemortem diagnosis of the perforated interventricular septum.


Pediatric and psychiatric aspects of the Yale Rooming-In Project.


The increasing incidence of cesarean section.


Seth Bird and his friends.

Seth Bird and his friends.


Role of county society members in medical legislation.


Six congenital cardiac anomalies in animals.


The semen of the thoroughbred.

The semen of the thoroughbred.


Possible congenital anomaly and rupture of the ureter in a yearling bull.


Aureomycin as a treatment of acute brucellosis of cattle.


Two cases of fracture in the horse.

Two cases of fracture in the horse.


Anesthetization of white-tailed deer.

Anesthetization of white-tailed deer.


A case of posterior paralysis in a cow.

A case of posterior paralysis in a cow.


Fracture of the tibia in a cow.

Fracture of the tibia in a cow.


The anemias in the trichostrongylidoses.


Studies on Newcastle disease; viability of live embryo Newcastle disease virus in buffered glycerol.


Fibropapillomas of the external genitalia of cattle.


The urease activity of certain pathogenic microorganisms isolated from animals.


Experimental transmission of the deer lungworm Leptostrongylus alpenae.