#!/usr/bin/env python3 """ Literature-Informed Road Traffic Injury & Trauma Dataset ========================================================= Generates realistic synthetic records of road traffic injury patients presenting to emergency departments in sub-Saharan Africa, including injury mechanism, severity, prehospital care, emergency management, and outcomes. Target population: Road traffic injury patients of all ages presenting to health facilities across SSA. DAG (Sampling Order): 1. demographics: age, sex, road_user_type 2. injury: mechanism, body_region, severity (GCS, ISS), fractures 3. prehospital: time_to_facility, transport, first_aid, referral 4. emergency_care: imaging, blood, surgery, ICU 5. complications: infection, VTE, organ_failure 6. outcome: survived/died, disability, LOS References (web-searched): ----------- [1] WHO Global Status Report on Road Safety (2023). 1.35M road deaths/yr. Africa highest rate: 26.6/100K vs 17.4 global. 90% in LMICs. Pedestrians/cyclists >50% in Africa. [2] Galvagno SM, et al. (2019). Prehospital trauma: <10% arrive within golden hour in many SSA settings. [3] Zafar SN, et al. (Lancet 2018). Trauma care Africa: mortality 30-40% for severe injuries (ISS>15). TBI leading cause of death. [4] WHO (2024). Road traffic injuries fact sheet. Young adults 15-44y most affected. Males 3x female risk. [5] Chalya PL, et al. (BMC Public Health 2012). Tanzania Bugando: RTI mortality 11.2%. Pedestrians 41%, motorcyclists 28%. Head injury 44%, extremity 38%. [6] Hyder AA, et al. (Bull WHO 2017). Cost of RTI in LMICs: 1-3% of GDP. Disability burden enormous. [7] Mwandri M, et al. (World J Emerg Surg 2020). Trauma in SSA: GCS on admission strongest predictor of mortality. [8] Mock C, et al. (Bull WHO 2012). Strengthening prehospital trauma care could prevent 54% of trauma deaths. """ import numpy as np import pandas as pd import argparse import os SCENARIOS = { 'trauma_centre': { 'description': 'Urban trauma centre with CT, ICU, neurosurgery, ' 'orthopaedics, blood bank (e.g., Muhimbili, ' 'Chris Hani Baragwanath, Kenyatta)', 'ct_available': True, 'icu_available': True, 'neurosurgery_available': True, 'blood_bank': True, 'ambulance_rate': 0.40, 'golden_hour_rate': 0.25, 'mortality': 0.08, }, 'district_hospital': { 'description': 'District hospital with basic X-ray, limited ' 'surgery, no ICU (e.g., district hospitals ' 'Tanzania, Malawi, Uganda)', 'ct_available': False, 'icu_available': False, 'neurosurgery_available': False, 'blood_bank': False, 'ambulance_rate': 0.10, 'golden_hour_rate': 0.10, 'mortality': 0.18, }, 'rural_health_centre': { 'description': 'Rural health centre, no imaging, no surgery, ' 'stabilise and refer (e.g., rural Nigeria, ' 'DRC, South Sudan)', 'ct_available': False, 'icu_available': False, 'neurosurgery_available': False, 'blood_bank': False, 'ambulance_rate': 0.03, 'golden_hour_rate': 0.03, 'mortality': 0.32, }, } ROAD_USER_TYPES = { 'pedestrian': 0.38, 'motorcyclist': 0.22, 'motor_vehicle_occupant': 0.18, 'cyclist': 0.10, 'passenger_minibus': 0.08, 'other': 0.04, } def generate_dataset(n=10000, seed=42, scenario='district_hospital'): rng = np.random.default_rng(seed) sc = SCENARIOS[scenario] users = list(ROAD_USER_TYPES.keys()) user_p = list(ROAD_USER_TYPES.values()) records = [] for idx in range(n): rec = {'id': idx + 1} # ── Step 1: Demographics [4][5] ── r = rng.random() if r < 0.08: rec['age_years'] = rng.integers(0, 15) elif r < 0.40: rec['age_years'] = rng.integers(15, 30) elif r < 0.65: rec['age_years'] = rng.integers(30, 45) elif r < 0.85: rec['age_years'] = rng.integers(45, 60) else: rec['age_years'] = rng.integers(60, 80) rec['sex'] = rng.choice(['M', 'F'], p=[0.75, 0.25]) rec['road_user_type'] = rng.choice(users, p=user_p) if rec['age_years'] < 15: rec['road_user_type'] = rng.choice( ['pedestrian', 'cyclist', 'passenger_minibus'], p=[0.60, 0.20, 0.20]) rec['helmet_use'] = 0 if rec['road_user_type'] == 'motorcyclist': rec['helmet_use'] = 1 if rng.random() < 0.25 else 0 rec['seatbelt_use'] = 0 if rec['road_user_type'] == 'motor_vehicle_occupant': rec['seatbelt_use'] = 1 if rng.random() < 0.15 else 0 rec['alcohol_involved'] = 1 if rng.random() < 0.25 else 0 rec['time_of_day'] = rng.choice( ['morning_6_12', 'afternoon_12_18', 'evening_18_24', 'night_0_6'], p=[0.20, 0.30, 0.30, 0.20]) rec['road_type'] = rng.choice( ['highway', 'urban_road', 'rural_road', 'intersection'], p=[0.25, 0.30, 0.30, 0.15]) # ── Step 2: Injury [5] ── rec['primary_body_region'] = rng.choice( ['head_neck', 'chest', 'abdomen', 'upper_extremity', 'lower_extremity', 'spine', 'pelvis', 'multiple'], p=[0.28, 0.10, 0.08, 0.12, 0.20, 0.06, 0.04, 0.12]) if rec['road_user_type'] in ('pedestrian', 'cyclist'): if rng.random() < 0.35: rec['primary_body_region'] = 'head_neck' rec['tbi'] = 1 if rec['primary_body_region'] == 'head_neck' else 0 if rec['primary_body_region'] == 'multiple' and rng.random() < 0.40: rec['tbi'] = 1 # GCS if rec['tbi']: gcs_roll = rng.random() if gcs_roll < 0.25: rec['gcs'] = rng.integers(3, 9) elif gcs_roll < 0.50: rec['gcs'] = rng.integers(9, 13) else: rec['gcs'] = rng.integers(13, 16) else: rec['gcs'] = rng.choice([14, 15], p=[0.20, 0.80]) rec['gcs_category'] = 'mild' if rec['gcs'] <= 8: rec['gcs_category'] = 'severe' elif rec['gcs'] <= 12: rec['gcs_category'] = 'moderate' # ISS if rec['primary_body_region'] == 'multiple': rec['iss'] = max(9, int(rng.normal(25, 10))) elif rec['tbi'] and rec['gcs'] <= 8: rec['iss'] = max(16, int(rng.normal(30, 10))) elif rec['primary_body_region'] in ('chest', 'abdomen'): rec['iss'] = max(4, int(rng.normal(16, 8))) else: rec['iss'] = max(1, int(rng.normal(10, 6))) rec['iss'] = min(rec['iss'], 75) rec['iss_category'] = 'minor' if rec['iss'] >= 25: rec['iss_category'] = 'critical' elif rec['iss'] >= 16: rec['iss_category'] = 'severe' elif rec['iss'] >= 9: rec['iss_category'] = 'moderate' rec['fracture'] = 0 if rec['primary_body_region'] in ('upper_extremity', 'lower_extremity', 'pelvis'): rec['fracture'] = 1 if rng.random() < 0.70 else 0 elif rec['primary_body_region'] == 'multiple': rec['fracture'] = 1 if rng.random() < 0.50 else 0 else: rec['fracture'] = 1 if rng.random() < 0.15 else 0 rec['open_fracture'] = 0 if rec['fracture']: rec['open_fracture'] = 1 if rng.random() < 0.30 else 0 rec['internal_bleeding'] = 0 if rec['primary_body_region'] in ('abdomen', 'chest', 'pelvis', 'multiple'): rec['internal_bleeding'] = 1 if rng.random() < 0.25 else 0 rec['spinal_cord_injury'] = 0 if rec['primary_body_region'] == 'spine': rec['spinal_cord_injury'] = 1 if rng.random() < 0.35 else 0 # ── Step 3: Prehospital [2][8] ── tp = np.array([sc['ambulance_rate'], 0.30, 0.10, 0.20, 0.05, 0.35 - sc['ambulance_rate']]) tp = np.maximum(tp, 0.01) tp = tp / tp.sum() rec['transport_mode'] = rng.choice( ['ambulance', 'private_vehicle', 'police', 'bystander', 'walked', 'motorcycle_taxi'], p=tp) rec['time_to_facility_hours'] = max(0.25, round(rng.exponential(3), 1)) rec['time_to_facility_hours'] = min(rec['time_to_facility_hours'], 48) rec['within_golden_hour'] = 1 if rec['time_to_facility_hours'] <= 1.0 else 0 rec['prehospital_first_aid'] = 1 if rng.random() < 0.20 else 0 rec['cervical_spine_immobilised'] = 0 if rec['transport_mode'] == 'ambulance': rec['cervical_spine_immobilised'] = 1 if rng.random() < 0.50 else 0 rec['referred_from_other'] = 1 if rng.random() < 0.25 else 0 # ── Step 4: Emergency Care ── rec['xray_done'] = 1 if rng.random() < 0.70 else 0 rec['ct_done'] = 0 if sc['ct_available'] and (rec['tbi'] or rec['iss'] >= 16): rec['ct_done'] = 1 if rng.random() < 0.65 else 0 rec['ultrasound_fast'] = 0 if rec['internal_bleeding'] or rec['primary_body_region'] in ('abdomen', 'pelvis'): rec['ultrasound_fast'] = 1 if rng.random() < 0.40 else 0 rec['blood_transfusion'] = 0 if rec['internal_bleeding'] or rec['iss'] >= 25: if sc['blood_bank']: rec['blood_transfusion'] = 1 if rng.random() < 0.45 else 0 else: rec['blood_transfusion'] = 1 if rng.random() < 0.10 else 0 rec['surgery_performed'] = 0 rec['surgery_type'] = 'none' if rec['internal_bleeding'] and rng.random() < 0.50: rec['surgery_performed'] = 1 rec['surgery_type'] = 'laparotomy' elif rec['tbi'] and rec['gcs'] <= 8 and sc['neurosurgery_available']: rec['surgery_performed'] = 1 if rng.random() < 0.30 else 0 if rec['surgery_performed']: rec['surgery_type'] = 'craniotomy' elif rec['fracture']: rec['surgery_performed'] = 1 if rng.random() < 0.35 else 0 if rec['surgery_performed']: rec['surgery_type'] = rng.choice( ['orif', 'external_fixation', 'amputation'], p=[0.50, 0.35, 0.15]) rec['icu_admission'] = 0 if sc['icu_available'] and (rec['gcs'] <= 8 or rec['iss'] >= 25): rec['icu_admission'] = 1 if rng.random() < 0.40 else 0 rec['intubated'] = 0 if rec['gcs'] <= 8: rec['intubated'] = 1 if rng.random() < (0.60 if sc['icu_available'] else 0.10) else 0 rec['tetanus_given'] = 1 if rng.random() < 0.65 else 0 rec['antibiotics_given'] = 1 if (rec['open_fracture'] or rec['surgery_performed']) else 0 # ── Step 5: Complications ── rec['wound_infection'] = 0 if rec['open_fracture'] or rec['surgery_performed']: rec['wound_infection'] = 1 if rng.random() < 0.15 else 0 rec['sepsis'] = 0 if rec['wound_infection'] or (rec['icu_admission'] and rng.random() < 0.10): rec['sepsis'] = 1 if rng.random() < 0.25 else 0 rec['vte'] = 0 if rec['fracture'] and rec['primary_body_region'] in ('lower_extremity', 'pelvis'): rec['vte'] = 1 if rng.random() < 0.05 else 0 # ── Step 6: Outcome [3][7] ── mort = sc['mortality'] if rec['gcs'] <= 8: mort *= 4.0 elif rec['gcs'] <= 12: mort *= 2.0 if rec['iss'] >= 25: mort *= 2.5 if rec['internal_bleeding'] and not rec['blood_transfusion']: mort *= 2.0 if not rec['within_golden_hour'] and rec['iss'] >= 16: mort *= 1.5 if rec['age_years'] > 60: mort *= 1.5 if rec['age_years'] < 5: mort *= 1.3 if rec['surgery_performed'] and rec['internal_bleeding']: mort *= 0.50 if rec['icu_admission']: mort *= 0.70 rec['outcome'] = 'died' if rng.random() < min(mort, 0.80) else 'survived' if rec['outcome'] == 'died': rec['length_of_stay_days'] = max(0, rng.integers(0, 7)) elif rec['iss'] >= 16: rec['length_of_stay_days'] = max(3, int(rng.normal(18, 10))) else: rec['length_of_stay_days'] = max(1, int(rng.normal(5, 3))) rec['disability_at_discharge'] = 'none' if rec['outcome'] == 'survived': if rec['spinal_cord_injury']: rec['disability_at_discharge'] = 'paralysis' elif rec['surgery_type'] == 'amputation': rec['disability_at_discharge'] = 'amputation' elif rec['tbi'] and rec['gcs'] <= 12: rec['disability_at_discharge'] = 'cognitive_impairment' elif rec['fracture']: rec['disability_at_discharge'] = 'mobility_limitation' records.append(rec) df = pd.DataFrame(records) print(f"\n{'='*65}") print(f"Road Traffic Injury — {scenario} (n={n}, seed={seed})") print(f"{'='*65}") print(f"\n Male: {(df['sex']=='M').mean()*100:.1f}%") print(f" Pedestrians: {(df['road_user_type']=='pedestrian').mean()*100:.1f}%") print(f" TBI: {df['tbi'].mean()*100:.1f}%") print(f" Severe (ISS≥16): {(df['iss']>=16).mean()*100:.1f}%") print(f" Within golden hour: {df['within_golden_hour'].mean()*100:.1f}%") print(f" Ambulance: {(df['transport_mode']=='ambulance').mean()*100:.1f}%") died = (df['outcome'] == 'died').sum() print(f" Mortality: {died} ({died/n*100:.1f}%)") return df if __name__ == '__main__': parser = argparse.ArgumentParser( description='Generate synthetic road traffic injury dataset') parser.add_argument('--scenario', type=str, default='district_hospital', choices=list(SCENARIOS.keys())) parser.add_argument('--n', type=int, default=10000) parser.add_argument('--seed', type=int, default=42) parser.add_argument('--output', type=str, default=None) parser.add_argument('--all-scenarios', action='store_true') args = parser.parse_args() os.makedirs('data', exist_ok=True) if args.all_scenarios: for sc_name in SCENARIOS: df = generate_dataset(n=args.n, seed=args.seed, scenario=sc_name) out = os.path.join('data', f'rti_{sc_name}.csv') df.to_csv(out, index=False) print(f" → Saved to {out}\n") else: df = generate_dataset(n=args.n, seed=args.seed, scenario=args.scenario) out = args.output or os.path.join('data', f'rti_{args.scenario}.csv') df.to_csv(out, index=False) print(f" → Saved to {out}")