"""PyTorch datasets for the three modalities. All datasets return a uniform batch dict so the trainer is modality-agnostic: {"slices": (T,3,H,W) | "vol": (1,D,H,W), "tab": (F,), "y": int, "subject_id": str} Tabular features are standardized with statistics FIT ON THE TRAINING FOLD ONLY (passed in as `tab_stats`) — never on the full dataset — to prevent leakage. Missing tabular values are median/mode-imputed from training-fold stats too. """ from __future__ import annotations from pathlib import Path import numpy as np import pandas as pd import torch from torch.utils.data import Dataset ROOT = Path(__file__).resolve().parents[3] PROC2D = ROOT / "data" / "processed_2d" PROC3D = ROOT / "data" / "processed_3d" # imagenet stats for pretrained backbones (applied after per-volume z-score, # so slices are re-scaled into the pretrained input regime) IMAGENET_MEAN = np.array([0.485, 0.456, 0.406], dtype=np.float32) IMAGENET_STD = np.array([0.229, 0.224, 0.225], dtype=np.float32) def fit_tab_stats(df: pd.DataFrame, features) -> dict: """Compute train-fold imputation + standardization stats for tab features.""" stats = {} for f in features: col = df[f].astype(float) med = float(col.median()) vals = col.fillna(med) mu, sd = float(vals.mean()), float(vals.std()) stats[f] = {"median": med, "mean": mu, "std": sd if sd > 1e-6 else 1.0} return stats def _encode_tab(row, features, stats) -> np.ndarray: out = np.zeros(len(features), dtype=np.float32) for i, f in enumerate(features): v = row[f] s = stats[f] if pd.isna(v): v = s["median"] out[i] = (float(v) - s["mean"]) / s["std"] return out class SliceDataset(Dataset): """2D / 2.5D tri-planar slices. planes/n_slices select which of the 27 to load. modality: slice2d -> single center axial slice returned as (1,3,H,W) slice25d -> the requested planes x n_slices as (T,3,H,W) """ def __init__(self, df, features, tab_stats, planes=("axial",), n_slices=9, modality="slice25d", augment=False): self.df = df.reset_index(drop=True) self.features = features self.stats = tab_stats self.planes = planes self.n_slices = n_slices self.modality = modality self.augment = augment def __len__(self): return len(self.df) def _load_plane(self, sid, plane): arr = np.load(PROC2D / sid / plane / "slices.npy").astype(np.float32) # (9,H,W) # select n_slices centered subset if fewer requested if self.n_slices < arr.shape[0]: start = (arr.shape[0] - self.n_slices) // 2 arr = arr[start:start + self.n_slices] return arr def _to_rgb(self, sl): # (H,W) -> (3,H,W) imagenet-normalized x = np.stack([sl, sl, sl], axis=0) x = (x - IMAGENET_MEAN[:, None, None]) / IMAGENET_STD[:, None, None] return x.astype(np.float32) def _augment(self, arr): # light aug on a (n,H,W) stack if not self.augment: return arr if np.random.rand() < 0.5: arr = arr + np.random.normal(0, 0.02, arr.shape).astype(np.float32) if np.random.rand() < 0.5: arr = arr * np.random.uniform(0.95, 1.05) return arr def __getitem__(self, idx): row = self.df.iloc[idx] sid = row["subject_id"] if self.modality == "slice2d": axial = self._load_plane(sid, "axial") center = axial[len(axial) // 2] slices = self._to_rgb(self._augment(center[None]))[0][None] # (1,3,H,W) else: planes = [] for p in self.planes: stack = self._augment(self._load_plane(sid, p)) planes.append(np.stack([self._to_rgb(s) for s in stack])) # (n,3,H,W) slices = np.concatenate(planes, axis=0) # (T,3,H,W) return { "slices": torch.from_numpy(slices), "tab": torch.from_numpy(_encode_tab(row, self.features, self.stats)), "y": int(row["class_id"]), "subject_id": sid, } class VolumeDataset(Dataset): """Whole-brain 3D volumes for CNN3D / transformer / hybrid models.""" def __init__(self, df, features, tab_stats, target="cnn3d", augment=False): self.df = df.reset_index(drop=True) self.features = features self.stats = tab_stats self.target = target # cnn3d (128^3) or tf3d (96x112x112) self.augment = augment def __len__(self): return len(self.df) def __getitem__(self, idx): row = self.df.iloc[idx] sid = row["subject_id"] vol = np.load(PROC3D / self.target / f"{sid}.npy").astype(np.float32) if self.augment and np.random.rand() < 0.5: vol = vol + np.random.normal(0, 0.02, vol.shape).astype(np.float32) return { "vol": torch.from_numpy(vol[None]), # (1,D,H,W) "tab": torch.from_numpy(_encode_tab(row, self.features, self.stats)), "y": int(row["class_id"]), "subject_id": sid, } class TabularDataset(Dataset): def __init__(self, df, features, tab_stats): self.df = df.reset_index(drop=True) self.features = features self.stats = tab_stats def __len__(self): return len(self.df) def __getitem__(self, idx): row = self.df.iloc[idx] return { "tab": torch.from_numpy(_encode_tab(row, self.features, self.stats)), "y": int(row["class_id"]), "subject_id": row["subject_id"], } def collate(items): """Uniform collate that stacks whichever tensors are present.""" out = {"y": torch.tensor([it["y"] for it in items]), "subject_id": [it["subject_id"] for it in items]} for key in ("slices", "vol", "tab"): if key in items[0]: out[key] = torch.stack([it[key] for it in items]) return out