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Objective","text_display":"\n\n\\section*{Primary Objective}","confidence":1,"confidence_rate":1},{"cnt":[[247,662],[1830,662],[1830,705],[247,705]],"region":{"top_left_x":247,"top_left_y":661,"width":1584,"height":44},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ef79fe582e764a248a4efd4e79416c92","type":"text","conversion_output":true,"text":"Our long-term objective is to reduce overall lower back pain (LBP) burden by testing scalable first-line","text_display":"\n\nOur long-term objective is to reduce overall lower back pain (LBP) burden by testing scalable first-line","confidence":1,"confidence_rate":1},{"cnt":[[245,705],[1760,705],[1760,750],[245,750]],"region":{"top_left_x":244,"top_left_y":704,"width":1516,"height":46},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c0aa53bb6b5c4ad5ade828e3d7e8eb3d","type":"text","conversion_output":true,"text":"non-pharmacologic strategies that address the biopsychosocial aspects of acute/sub-acute LBP and","text_display":" non-pharmacologic strategies that address the biopsychosocial aspects of acute/sub-acute LBP and","confidence":0.99853515625,"confidence_rate":0.9999854860688677},{"cnt":[[247,748],[1760,748],[1760,793],[247,793]],"region":{"top_left_x":247,"top_left_y":747,"width":1513,"height":46},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f645ddc4a47a4448be5eb44a37e1e28e","type":"text","conversion_output":true,"text":"prevent transition to chronic LBP (cLBP). We will assess the effectiveness of Spinal Manipulation","text_display":" prevent transition to chronic LBP (cLBP). We will assess the effectiveness of Spinal Manipulation","confidence":1,"confidence_rate":1},{"cnt":[[247,793],[1807,793],[1807,836],[247,836]],"region":{"top_left_x":247,"top_left_y":792,"width":1560,"height":44},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c9810ac3afe7409498f07b2b562d96be","type":"text","conversion_output":true,"text":"Therapy (SMT), Supported Self-Management (SSM), and SMT+SSM relative to Medical Care (MC).","text_display":" Therapy (SMT), Supported Self-Management (SSM), and SMT+SSM relative to Medical Care (MC).","confidence":1,"confidence_rate":1},{"cnt":[[243,877],[578,877],[578,926],[243,926]],"region":{"top_left_x":242,"top_left_y":876,"width":336,"height":50},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8c68f56b928d40e6adeaf85e4709efe2","type":"section_header","conversion_output":false,"children_ids":["ee937515dfe14dd099b99dc8a2faa7f2"],"text":"","text_display":""},{"cnt":[[247,881],[574,881],[574,922],[247,922]],"region":{"top_left_x":247,"top_left_y":880,"width":327,"height":42},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ee937515dfe14dd099b99dc8a2faa7f2","type":"text","conversion_output":true,"parent_id":"8c68f56b928d40e6adeaf85e4709efe2","text":"Secondary Objective","text_display":"\n\n\\section*{Secondary Objective}","confidence":1,"confidence_rate":1},{"cnt":[[247,924],[1811,924],[1811,969],[247,969]],"region":{"top_left_x":247,"top_left_y":923,"width":1565,"height":46},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a0c164db4e1a49a49fc48fe097edfc70","type":"text","conversion_output":true,"text":"To facilitate translation and dissemination across health professions and other clinical settings we will","text_display":"\n\nTo facilitate translation and dissemination across health professions and other clinical settings we will","confidence":1,"confidence_rate":1},{"cnt":[[247,967],[1646,967],[1646,1012],[247,1012]],"region":{"top_left_x":247,"top_left_y":966,"width":1399,"height":46},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d62765c68d0b43c3bc5b8cfa7a0ec2ca","type":"text","conversion_output":true,"text":"gather contextual data using mixed methods guided by the Reach, Effectiveness, Adoption,","text_display":" gather contextual data using mixed methods guided by the Reach, Effectiveness, Adoption,","confidence":1,"confidence_rate":1},{"cnt":[[247,1010],[1820,1010],[1820,1055],[247,1055]],"region":{"top_left_x":247,"top_left_y":1009,"width":1573,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"00dc5d3f5f5a4d47b7bbc1e26d548dc0","type":"text","conversion_output":true,"text":"Implementation, and Maintenance (RE- AIM) framework. Qualitative data will lend context regarding","text_display":" Implementation, and Maintenance (RE- AIM) framework. Qualitative data will lend context regarding","confidence":1,"confidence_rate":1},{"cnt":[[247,1057],[1820,1057],[1820,1102],[247,1102]],"region":{"top_left_x":247,"top_left_y":1057,"width":1573,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bae2a150f10e4946889b905c5aa8f0fe","type":"text","conversion_output":true,"text":"patients', staff, providers' and health system leaders' perceptions of barriers and facilitators associated","text_display":" patients', staff, providers' and health system leaders' perceptions of barriers and facilitators associated","confidence":0.99951171875,"confidence_rate":0.9999956392907748},{"cnt":[[247,1100],[1781,1100],[1781,1145],[247,1145]],"region":{"top_left_x":247,"top_left_y":1100,"width":1535,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"31a96a22ea794b038faf213d1c4e4429","type":"text","conversion_output":true,"text":"with the interventions; quantitative data collection will provide insight into intervention application,","text_display":" with the interventions; quantitative data collection will provide insight into intervention application,","confidence":0.99853515625,"confidence_rate":0.9999865513043565},{"cnt":[[247,1143],[935,1143],[935,1188],[247,1188]],"region":{"top_left_x":247,"top_left_y":1142,"width":688,"height":47},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ff4eaed5dd5c4a7f91daeb4c2385d59f","type":"text","conversion_output":true,"text":"adherence, fidelity, and provider confidence.","text_display":" adherence, fidelity, and provider confidence.","confidence":0.9951171875,"confidence_rate":0.9999021093440684},{"cnt":[[245,1233],[642,1233],[642,1285],[245,1285]],"region":{"top_left_x":244,"top_left_y":1233,"width":399,"height":52},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8ea5ed318348472f9948641b23671c05","type":"section_header","conversion_output":false,"children_ids":["b0f24f8e158c45978414c98d847f5f62"],"text":"","text_display":""},{"cnt":[[247,1238],[638,1238],[638,1283],[247,1283]],"region":{"top_left_x":247,"top_left_y":1237,"width":392,"height":46},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b0f24f8e158c45978414c98d847f5f62","type":"text","conversion_output":true,"parent_id":"8ea5ed318348472f9948641b23671c05","text":"Design and Outcomes","text_display":"\n\n\\section*{Design and Outcomes}","confidence":0.9970703125,"confidence_rate":0.9998777579957132},{"cnt":[[247,1302],[1772,1302],[1772,1347],[247,1347]],"region":{"top_left_x":247,"top_left_y":1301,"width":1526,"height":47},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"439b40269f494964b156c5c3a6b55337","type":"text","conversion_output":true,"text":"This is multi-site, predominantly pragmatic, phase III randomized trial using a \\(2 \\times 2\\) factorial design.","text_display":"\n\nThis is multi-site, predominantly pragmatic, phase III randomized trial using a \\(2 \\times 2\\) factorial design.","confidence":1,"confidence_rate":1},{"cnt":[[247,1347],[1790,1347],[1790,1394],[247,1394]],"region":{"top_left_x":247,"top_left_y":1347,"width":1543,"height":48},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8a4dd0451f264ef796ab2bef9c4a1836","type":"text","conversion_output":true,"text":"Participants will be randomized to one of the following treatment groups: (1) SMT, (2) SSM, (3) the","text_display":" Participants will be randomized to one of the following treatment groups: (1) SMT, (2) SSM, (3) the","confidence":1,"confidence_rate":1},{"cnt":[[247,1392],[1811,1392],[1811,1437],[247,1437]],"region":{"top_left_x":247,"top_left_y":1392,"width":1565,"height":46},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b7ac07cf37554837a246adbd230c3149","type":"text","conversion_output":true,"text":"combination of SMT+SSM, or (4) MC. Physical therapists (PTs) and chiropractors (DCs) will deliver","text_display":" combination of SMT+SSM, or (4) MC. Physical therapists (PTs) and chiropractors (DCs) will deliver","confidence":1,"confidence_rate":1},{"cnt":[[247,1435],[1751,1435],[1751,1480],[247,1480]],"region":{"top_left_x":247,"top_left_y":1435,"width":1504,"height":46},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9dd0bc664b6041d4ae1abec2cbedc594","type":"text","conversion_output":true,"text":"SMT and SSM, and medical providers will deliver the MC. The study has 2 primary effectiveness","text_display":" SMT and SSM, and medical providers will deliver the MC. The study has 2 primary effectiveness","confidence":1,"confidence_rate":1},{"cnt":[[245,1480],[956,1480],[956,1523],[245,1523]],"region":{"top_left_x":244,"top_left_y":1480,"width":713,"height":44},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b1372b1faf7645fe9d086732d7250048","type":"text","conversion_output":true,"text":"research questions with different time frames:","text_display":" research questions with different time frames:","confidence":1,"confidence_rate":1},{"cnt":[[312,1568],[1783,1568],[1783,1613],[312,1613]],"region":{"top_left_x":311,"top_left_y":1568,"width":1473,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"693b91ec73fb484e9ae97831ff88ce12","type":"text","conversion_output":true,"text":"1. Prevention of cLBP at 12 months as measured by LBP Impact (from Promis-29) scale: 8-50","text_display":"\n1. Prevention of cLBP at 12 months as measured by LBP Impact (from Promis-29) scale: 8-50","confidence":0.87841796875,"confidence_rate":0.9986644724858328},{"cnt":[[374,1611],[943,1611],[943,1656],[374,1656]],"region":{"top_left_x":373,"top_left_y":1611,"width":571,"height":46},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d08fed1e833c40e496f54b17bdf5c145","type":"text","conversion_output":true,"text":"(Analysis of AUC for months 10-12)","text_display":" (Analysis of AUC for months 10-12)","confidence":1,"confidence_rate":1},{"cnt":[[309,1697],[1785,1697],[1785,1745],[309,1745]],"region":{"top_left_x":309,"top_left_y":1697,"width":1477,"height":48},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d01ea9a70de545cda11f760a040a9b1d","type":"text","conversion_output":true,"text":"2. Average pain intensity and low back disability over 1 year as measured by weekly NRS and","text_display":"\n2. Average pain intensity and low back disability over 1 year as measured by weekly NRS and","confidence":1,"confidence_rate":1},{"cnt":[[372,1745],[741,1745],[741,1790],[372,1790]],"region":{"top_left_x":371,"top_left_y":1744,"width":371,"height":46},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"aab0ca8de0b148e88afde09acffe0286","type":"text","conversion_output":true,"text":"monthly RMDQ scores.","text_display":" monthly RMDQ scores.","confidence":1,"confidence_rate":1},{"cnt":[[247,1830],[1798,1830],[1798,1876],[247,1876]],"region":{"top_left_x":247,"top_left_y":1830,"width":1552,"height":46},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"326b0ee8ecce44e7964238abfebad5fb","type":"text","conversion_output":true,"text":"Secondary outcome measures include: recovery, NIH minimal dataset including the Patient Reported","text_display":"\n\nSecondary outcome measures include: recovery, NIH minimal dataset including the Patient Reported","confidence":1,"confidence_rate":1},{"cnt":[[247,1873],[1833,1873],[1833,1919],[247,1919]],"region":{"top_left_x":247,"top_left_y":1873,"width":1586,"height":46},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"12ca2e2f7dd44a2783bb3ad242b53159","type":"text","conversion_output":true,"text":"Outcome Measurement Information System-29 (PROMIS-29) and other measures of LBP burden (e.g.,","text_display":" Outcome Measurement Information System-29 (PROMIS-29) and other measures of LBP burden (e.g.,","confidence":1,"confidence_rate":1},{"cnt":[[245,1921],[1304,1921],[1304,1966],[245,1966]],"region":{"top_left_x":244,"top_left_y":1920,"width":1061,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d401a700a41b45399a7c611e288b9cc4","type":"text","conversion_output":true,"text":"productivity loss, health care and medication use, including opioids).","text_display":" productivity loss, health care and medication use, including opioids).","confidence":1,"confidence_rate":1},{"cnt":[[245,2028],[743,2028],[743,2073],[245,2073]],"region":{"top_left_x":244,"top_left_y":2028,"width":500,"height":46},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dc351dc3e3584907bd3f6ee2198e4073","type":"section_header","conversion_output":false,"children_ids":["1fc7343aa355492b852e4c01b8c2ac44"],"text":"","text_display":""},{"cnt":[[249,2032],[741,2032],[741,2069],[249,2069]],"region":{"top_left_x":249,"top_left_y":2032,"width":493,"height":37},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1fc7343aa355492b852e4c01b8c2ac44","type":"text","conversion_output":true,"parent_id":"dc351dc3e3584907bd3f6ee2198e4073","text":"Interventions and Duration","text_display":"\n\n\\section*{Interventions and Duration}","confidence":1,"confidence_rate":1},{"cnt":[[247,2097],[1785,2097],[1785,2142],[247,2142]],"region":{"top_left_x":247,"top_left_y":2096,"width":1539,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b6b1a9318ae74170bc357b040d73e624","type":"text","conversion_output":true,"text":"All participants will be followed for 12 months after randomization. The initial treatment period is 8","text_display":"\n\nAll participants will be followed for 12 months after randomization. The initial treatment period is 8","confidence":1,"confidence_rate":1},{"cnt":[[247,2140],[1846,2140],[1846,2185],[247,2185]],"region":{"top_left_x":247,"top_left_y":2139,"width":1599,"height":46},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"00aac17975b3407d8776b670150ea72c","type":"text","conversion_output":true,"text":"weeks. Decisions regarding visit frequency will be made collaboratively by the provider and participant,","text_display":" weeks. Decisions regarding visit frequency will be made collaboratively by the provider and participant,","confidence":1,"confidence_rate":1},{"cnt":[[245,2185],[1712,2185],[1712,2228],[245,2228]],"region":{"top_left_x":244,"top_left_y":2184,"width":1469,"height":44},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f94e8695f373407abf914268689ed426","type":"text","conversion_output":true,"text":"as is typical in real-world stings. Participants will be required to attend \\(\\geq 75 \\%\\) of the prescribed","text_display":" as is typical in real-world stings. Participants will be required to attend \\(\\geq 75 \\%\\) of the prescribed","confidence":1,"confidence_rate":1},{"cnt":[[247,2228],[1738,2228],[1738,2271],[247,2271]],"region":{"top_left_x":247,"top_left_y":2227,"width":1492,"height":44},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"882e223ba0a94efba45ccb6f1db8cd16","type":"text","conversion_output":true,"text":"intervention visits to be considered compliant. In addition, participants have the option to receive","text_display":" intervention visits to be considered compliant. In addition, participants have the option to receive","confidence":1,"confidence_rate":1},{"cnt":[[247,2273],[1811,2273],[1811,2318],[247,2318]],"region":{"top_left_x":247,"top_left_y":2273,"width":1565,"height":46},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"addd617fea2644368a194196667dec08","type":"text","conversion_output":true,"text":"additional treatment in the group to which they were randomized if they experience a recurrence of an","text_display":" additional treatment in the group to which they were randomized if they experience a recurrence of an","confidence":1,"confidence_rate":1},{"cnt":[[247,2316],[1762,2316],[1762,2361],[247,2361]],"region":{"top_left_x":247,"top_left_y":2316,"width":1515,"height":46},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"60d6c18399e94bf8be734d902342d774","type":"text","conversion_output":true,"text":"acute LBP episode during the 10 -month follow-up period. Specifically, if the patient experiences a","text_display":" acute LBP episode during the 10 -month follow-up period. Specifically, if the patient experiences a","confidence":0.8740234375,"confidence_rate":0.9987423981053984},{"cnt":[[245,2359],[1867,2359],[1867,2404],[245,2404]],"region":{"top_left_x":244,"top_left_y":2358,"width":1623,"height":47},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7ef65682c1e84ea490bbf8a60059631a","type":"text","conversion_output":true,"text":"recurrence of bothersome low back pain (e.g., a \"flare up\" lasting more than two weeks) the provider will","text_display":" recurrence of bothersome low back pain (e.g., a \"flare up\" lasting more than two weeks) the provider will","confidence":0.99951171875,"confidence_rate":0.9999955600053285},{"cnt":[[245,2402],[1717,2402],[1717,2447],[245,2447]],"region":{"top_left_x":244,"top_left_y":2401,"width":1473,"height":47},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"adc0f45566754d7ea241ffe00a5ae27d","type":"text","conversion_output":true,"text":"assess the patient and decide if additional visits are necessary over the 12 month research study.","text_display":" assess the patient and decide if additional visits are necessary over the 12 month research study.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1871,2582],[1871,2617],[1504,2617]],"region":{"top_left_x":1503,"top_left_y":2582,"width":369,"height":35},"line":47,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"e00922f197ff4743be4b2fafa3da5abe","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 15","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-16","page":16,"lines":[{"cnt":[[241,249],[715,249],[715,303],[241,303]],"region":{"top_left_x":240,"top_left_y":249,"width":476,"height":54},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a8d8eebf48f24d65b562b613d6f6faf2","type":"section_header","conversion_output":false,"children_ids":["ff65184fb6d3404bae72b71464b080ab"],"text":"","text_display":""},{"cnt":[[245,254],[711,254],[711,299],[245,299]],"region":{"top_left_x":244,"top_left_y":253,"width":468,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ff65184fb6d3404bae72b71464b080ab","type":"text","conversion_output":true,"parent_id":"a8d8eebf48f24d65b562b613d6f6faf2","text":"Sample Size and Population","text_display":"\n\n\\section*{Sample Size and Population}","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1858,296],[1858,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1615,"height":46},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2a0afd3d79aa4f01b3b5131c3bef2ee7","type":"text","conversion_output":true,"text":"A total of 1000 patients age 18 and above will be enrolled with nonspecific LBP of 2-12 weeks duration,","text_display":"\n\nA total of 1000 patients age 18 and above will be enrolled with nonspecific LBP of 2-12 weeks duration,","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[1751,339],[1751,387],[245,387]],"region":{"top_left_x":244,"top_left_y":339,"width":1507,"height":48},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1e157462addd46df8a4b6864c98fd51b","type":"text","conversion_output":true,"text":"at medium or high risk of developing cLBP. The randomization will use 2 strata: Site and Risk of","text_display":" at medium or high risk of developing cLBP. The randomization will use 2 strata: Site and Risk of","confidence":1,"confidence_rate":1},{"cnt":[[245,382],[698,382],[698,432],[245,432]],"region":{"top_left_x":244,"top_left_y":382,"width":455,"height":50},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1100c97c023342f3870187d401218de4","type":"text","conversion_output":true,"text":"chronicity (medium or high).","text_display":" chronicity (medium or high).","confidence":1,"confidence_rate":1},{"cnt":[[241,486],[720,486],[720,544],[241,544]],"region":{"top_left_x":240,"top_left_y":485,"width":480,"height":59},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"51ff5049efd74e1e8de3cf903f81db62","type":"section_header","conversion_output":false,"children_ids":["fe049cf4945744c7a4a1fd8a224bad7c"],"text":"","text_display":""},{"cnt":[[245,490],[713,490],[713,535],[245,535]],"region":{"top_left_x":244,"top_left_y":489,"width":470,"height":46},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"fe049cf4945744c7a4a1fd8a224bad7c","type":"text","conversion_output":true,"parent_id":"51ff5049efd74e1e8de3cf903f81db62","text":"1. STUDY OBJECTIVES","text_display":"\n\n\\section*{1. STUDY OBJECTIVES}","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1824,559],[1824,604],[245,604]],"region":{"top_left_x":244,"top_left_y":558,"width":1581,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a0d4b740d79840b7bb008feb4007ae7b","type":"text","conversion_output":true,"text":"The US is in the midst of an unprecedented pain management crisis, with chronic pain impacting more","text_display":"\n\nThe US is in the midst of an unprecedented pain management crisis, with chronic pain impacting more","confidence":1,"confidence_rate":1},{"cnt":[[245,602],[1876,602],[1876,649],[245,649]],"region":{"top_left_x":244,"top_left_y":601,"width":1632,"height":48},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1f4012ec81e749fda81d8d1291886414","type":"text","conversion_output":true,"text":"Americans than heart disease, diabetes, and cancer combined. \\({ }^{1}\\) Low back pain (LBP) is the most common","text_display":" Americans than heart disease, diabetes, and cancer combined. \\({ }^{1}\\) Low back pain (LBP) is the most common","confidence":1,"confidence_rate":1},{"cnt":[[245,645],[1841,645],[1841,694],[245,694]],"region":{"top_left_x":244,"top_left_y":644,"width":1598,"height":50},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f7a110b49242499aaed0e6ca863283a6","type":"text","conversion_output":true,"text":"chronic pain condition in adults and one of the leading cause of disability worldwide. \\({ }^{2-4}\\) Evidence based","text_display":" chronic pain condition in adults and one of the leading cause of disability worldwide. \\({ }^{2-4}\\) Evidence based","confidence":1,"confidence_rate":1},{"cnt":[[245,692],[1841,692],[1841,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1598,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"acc2744ab4a5463f86c8f0ca39f8eb09","type":"text","conversion_output":true,"text":"guidelines have recommended non-pharmacological treatments like spinal manipulation and behavioral","text_display":" guidelines have recommended non-pharmacological treatments like spinal manipulation and behavioral","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1785,735],[1785,780],[245,780]],"region":{"top_left_x":244,"top_left_y":734,"width":1542,"height":46},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"74dc85a74dc843ca94f5e4088a5a220f","type":"text","conversion_output":true,"text":"approaches for LBP for nearly a decade, \\({ }^{5}\\) however uptake in practice has been poor. Further, little is","text_display":" approaches for LBP for nearly a decade, \\({ }^{5}\\) however uptake in practice has been poor. Further, little is","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1850,778],[1850,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1606,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34f2e860b7074f6b9122e0d109bd9882","type":"text","conversion_output":true,"text":"known about the role of these treatments in secondary prevention of chronic LBP (cLBP), especially for","text_display":" known about the role of these treatments in secondary prevention of chronic LBP (cLBP), especially for","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1807,821],[1807,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1563,"height":51},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"403e16ef065e40b4b54ad322bb0f016e","type":"text","conversion_output":true,"text":"patients with biopsychosocial risk factors. With burgeoning costs of cLBP and mounting evidence of","text_display":" patients with biopsychosocial risk factors. With burgeoning costs of cLBP and mounting evidence of","confidence":0.99755859375,"confidence_rate":0.9999762683268261},{"cnt":[[245,864],[1869,864],[1869,913],[245,913]],"region":{"top_left_x":244,"top_left_y":863,"width":1626,"height":51},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"521d504d6529424db4645cefcd1d5b15","type":"text","conversion_output":true,"text":"ineffectiveness and harms of commonly used drug treatments, including opioids, \\({ }^{6-8}\\) there is a critical need","text_display":" ineffectiveness and harms of commonly used drug treatments, including opioids, \\({ }^{6-8}\\) there is a critical need","confidence":1,"confidence_rate":1},{"cnt":[[245,907],[1800,907],[1800,956],[245,956]],"region":{"top_left_x":244,"top_left_y":906,"width":1557,"height":51},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3e3e4b1b996a4652bcc2db322e2892bc","type":"text","conversion_output":true,"text":"for research on non-pharmacological treatments for cLBP prevention that can be readily translated to","text_display":" for research on non-pharmacological treatments for cLBP prevention that can be readily translated to","confidence":0.99951171875,"confidence_rate":0.9999953485775026},{"cnt":[[245,954],[385,954],[385,1003],[245,1003]],"region":{"top_left_x":244,"top_left_y":953,"width":141,"height":51},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9aae483d4016489ab9c7efcc941e30f9","type":"text","conversion_output":true,"text":"practice.","text_display":" practice.","confidence":1,"confidence_rate":1},{"cnt":[[245,1040],[1863,1040],[1863,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1039,"width":1619,"height":51},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5a48fb67792643ab8974a44704182bde","type":"text","conversion_output":true,"text":"Our long-term objective is to reduce overall LBP burden by testing scalable first-line non-pharmacologic","text_display":"\n\nOur long-term objective is to reduce overall LBP burden by testing scalable first-line non-pharmacologic","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1878,1087],[1878,1132],[245,1132]],"region":{"top_left_x":244,"top_left_y":1087,"width":1634,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"738765033b79409fbe5493ecc8855f50","type":"text","conversion_output":true,"text":"strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to cLBP.","text_display":" strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to cLBP.","confidence":0.99951171875,"confidence_rate":0.9999956000051925},{"cnt":[[245,1130],[1824,1130],[1824,1177],[245,1177]],"region":{"top_left_x":244,"top_left_y":1130,"width":1581,"height":48},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"94cf27c0f4e0460e967358342d5923d6","type":"text","conversion_output":true,"text":"We will assess the effectiveness of Spinal Manipulation Therapy (SMT), Supported Self-Management","text_display":" We will assess the effectiveness of Spinal Manipulation Therapy (SMT), Supported Self-Management","confidence":1,"confidence_rate":1},{"cnt":[[245,1173],[1858,1173],[1858,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1173,"width":1615,"height":50},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8021aec1a3e845238f0614abf4ea91cb","type":"text","conversion_output":true,"text":"(SSM), and SMT+SSM relative to Medical Care (MC) in a randomized trial using a \\(2 \\times 2\\) factorial design.","text_display":" (SSM), and SMT+SSM relative to Medical Care (MC) in a randomized trial using a \\(2 \\times 2\\) factorial design.","confidence":0.9825031401123852,"confidence_rate":0.9998365713262849},{"cnt":[[245,1216],[1820,1216],[1820,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1576,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3b2b35f7fd644340977f6cf5377e4fad","type":"text","conversion_output":true,"text":"A total of 1000 patients will be enrolled with nonspecific LBP of 2-12 weeks duration, at medium and","text_display":" A total of 1000 patients will be enrolled with nonspecific LBP of 2-12 weeks duration, at medium and","confidence":0.8671875,"confidence_rate":0.9986814250607259},{"cnt":[[245,1259],[1863,1259],[1863,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1258,"width":1619,"height":51},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7ee5e3eafb0f46c18459fad08ede5095","type":"text","conversion_output":true,"text":"high risk of developing cLBP using the Subgroups for Targeted Treatment (STarT) Back Screening Tool","text_display":" high risk of developing cLBP using the Subgroups for Targeted Treatment (STarT) Back Screening Tool","confidence":0.99951171875,"confidence_rate":0.9999953038523912},{"cnt":[[245,1306],[1781,1306],[1781,1354],[245,1354]],"region":{"top_left_x":244,"top_left_y":1306,"width":1538,"height":48},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7cbc51a888f9418a83669c62fc03ae2d","type":"text","conversion_output":true,"text":"(SBST). Physical therapists (PTs) and chiropractors (DCs) will deliver SMT and SSM, and medical","text_display":" (SBST). Physical therapists (PTs) and chiropractors (DCs) will deliver SMT and SSM, and medical","confidence":1,"confidence_rate":1},{"cnt":[[245,1349],[1796,1349],[1796,1399],[245,1399]],"region":{"top_left_x":244,"top_left_y":1349,"width":1553,"height":50},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"283679b1d2a4464cb049f61fb920ab0f","type":"text","conversion_output":true,"text":"providers will deliver the MC. This multi-site, predominantly pragmatic, phase III trial has two main","text_display":" providers will deliver the MC. This multi-site, predominantly pragmatic, phase III trial has two main","confidence":1,"confidence_rate":1},{"cnt":[[245,1392],[421,1392],[421,1442],[245,1442]],"region":{"top_left_x":244,"top_left_y":1392,"width":178,"height":50},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"26b160a50d214128a2208009d51b2775","type":"text","conversion_output":true,"text":"objectives:","text_display":" objectives:","confidence":1,"confidence_rate":1},{"cnt":[[301,1517],[782,1517],[782,1583],[301,1583]],"region":{"top_left_x":300,"top_left_y":1516,"width":483,"height":68},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6885ca90237a4ed2a0ba0d029189ec92","type":"section_header","conversion_output":false,"children_ids":["07efa8e515a742529a109f67f1317969"],"text":"","text_display":""},{"cnt":[[309,1521],[776,1521],[776,1575],[309,1575]],"region":{"top_left_x":309,"top_left_y":1521,"width":467,"height":54},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"07efa8e515a742529a109f67f1317969","type":"text","conversion_output":true,"parent_id":"6885ca90237a4ed2a0ba0d029189ec92","text":"1.1 Primary Objective","text_display":"\n\n\\subsection*{1.1 Primary Objective}","confidence":1,"confidence_rate":1},{"cnt":[[245,1635],[1457,1635],[1457,1687],[245,1687]],"region":{"top_left_x":244,"top_left_y":1634,"width":1213,"height":53},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d810ebee4de7494f948ba9c68b348f99","type":"text","conversion_output":true,"text":"EFFECTIVENESS will be determined via three primary outcomes measures:","text_display":"\n\nEFFECTIVENESS will be determined via three primary outcomes measures:","confidence":1,"confidence_rate":1},{"cnt":[[309,1723],[1837,1723],[1837,1772],[309,1772]],"region":{"top_left_x":309,"top_left_y":1723,"width":1528,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"169e9435dd724d4780a3041e3b11c77d","type":"text","conversion_output":true,"text":"1. Prevention of cLBP that is impactful at \\(10-12\\) months follow-up ( \\(8-50\\), LBP Impact scale using","text_display":"\n1. Prevention of cLBP that is impactful at \\(10-12\\) months follow-up ( \\(8-50\\), LBP Impact scale using","confidence":0.5024996407009894,"confidence_rate":0.993648402090409},{"cnt":[[370,1766],[1772,1766],[1772,1815],[370,1815]],"region":{"top_left_x":369,"top_left_y":1766,"width":1404,"height":50},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fc6be91f3992417c8adf0527df223935","type":"text","conversion_output":true,"text":"mean from months 10-12). The LBP impact scale includes measures of pain intensity, pain","text_display":" mean from months 10-12). The LBP impact scale includes measures of pain intensity, pain","confidence":0.994140625,"confidence_rate":0.9999361258608116},{"cnt":[[370,1813],[1459,1813],[1459,1858],[370,1858]],"region":{"top_left_x":369,"top_left_y":1813,"width":1090,"height":46},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cd20bcf2e0004a7c8e3adfbd6bf36996","type":"text","conversion_output":true,"text":"interference, and physical function from the PROMIS-29 Profile v2.0)","text_display":" interference, and physical function from the PROMIS-29 Profile v2.0)","confidence":0.9990234375,"confidence_rate":0.999986615984802},{"cnt":[[305,1856],[1841,1856],[1841,1901],[305,1901]],"region":{"top_left_x":305,"top_left_y":1856,"width":1537,"height":46},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3bab6384d0ba4aefa4bdc6d8cc2a9103","type":"text","conversion_output":true,"text":"2. Average pain intensity over 12 months post-randomization ( \\(0-10\\) numerical rating scale (NRS))","text_display":"\n2. Average pain intensity over 12 months post-randomization ( \\(0-10\\) numerical rating scale (NRS))","confidence":1,"confidence_rate":1},{"cnt":[[305,1899],[1798,1899],[1798,1949],[305,1949]],"region":{"top_left_x":305,"top_left_y":1899,"width":1494,"height":50},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0fff46f47b444109a0d7c66a30d88925","type":"text","conversion_output":true,"text":"3. Average disability over 12 months post-randomization ( \\(0-24\\) scale, Roland Morris Disability","text_display":"\n3. Average disability over 12 months post-randomization ( \\(0-24\\) scale, Roland Morris Disability","confidence":0.98388671875,"confidence_rate":0.9998453023309318},{"cnt":[[370,1942],[730,1942],[730,1992],[370,1992]],"region":{"top_left_x":369,"top_left_y":1942,"width":362,"height":50},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"546a93d19ed042c4af5c734ea02c6e98","type":"text","conversion_output":true,"text":"Questionnaire (RMD))","text_display":" Questionnaire (RMD))","confidence":1,"confidence_rate":1},{"cnt":[[245,2028],[1751,2028],[1751,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2028,"width":1507,"height":50},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34dbac348ddb478f85d38e65811e9cfc","type":"text","conversion_output":true,"text":"Our hypotheses are informed by our prior research. \\({ }^{79-23}\\) Hypothesized quantifiable differences are","text_display":"\n\nOur hypotheses are informed by our prior research. \\({ }^{79-23}\\) Hypothesized quantifiable differences are","confidence":0.927838530158624,"confidence_rate":0.9993374093534771},{"cnt":[[245,2075],[988,2075],[988,2121],[245,2121]],"region":{"top_left_x":244,"top_left_y":2075,"width":745,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ac49a20a989643a9879b84e2cb948e6a","type":"text","conversion_output":true,"text":"outlined in the statistical considerations section.","text_display":" outlined in the statistical considerations section.","confidence":1,"confidence_rate":1},{"cnt":[[245,2161],[1762,2161],[1762,2211],[245,2211]],"region":{"top_left_x":244,"top_left_y":2161,"width":1518,"height":50},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"17139f3f33384f07bcedbdc20c81e01b","type":"text","conversion_output":true,"text":"Secondary effectiveness objectives will assess: a) secondary outcomes including but not limited to","text_display":"\n\nSecondary effectiveness objectives will assess: a) secondary outcomes including but not limited to","confidence":1,"confidence_rate":1},{"cnt":[[245,2206],[1846,2206],[1846,2254],[245,2254]],"region":{"top_left_x":244,"top_left_y":2206,"width":1602,"height":48},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"85f65ae7cd974928b55d7617e2ab500c","type":"text","conversion_output":true,"text":"recovery, the Patient Reported Outcome Measurement Information System-29 (PROMIS-29), and other","text_display":" recovery, the Patient Reported Outcome Measurement Information System-29 (PROMIS-29), and other","confidence":1,"confidence_rate":1},{"cnt":[[245,2252],[1828,2252],[1828,2299],[245,2299]],"region":{"top_left_x":244,"top_left_y":2251,"width":1585,"height":48},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"03c50bae05784bb9bc2cb29d99c74315","type":"text","conversion_output":true,"text":"measures of LBP burden (e.g., productivity loss, health care and medication use, including opioids); b)","text_display":" measures of LBP burden (e.g., productivity loss, health care and medication use, including opioids); b)","confidence":1,"confidence_rate":1},{"cnt":[[245,2295],[1824,2295],[1824,2344],[245,2344]],"region":{"top_left_x":244,"top_left_y":2294,"width":1581,"height":50},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6ac03bffe446472ba1aa464b6904140f","type":"text","conversion_output":true,"text":"primary outcomes in pre-specified subgroups of acute vs. sub-acute and medium vs. high risk of cLBP","text_display":" primary outcomes in pre-specified subgroups of acute vs. sub-acute and medium vs. high risk of cLBP","confidence":1,"confidence_rate":1},{"cnt":[[245,2340],[1579,2340],[1579,2387],[245,2387]],"region":{"top_left_x":244,"top_left_y":2339,"width":1336,"height":48},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"68812d6feb6840ff9c2708b16a9b04b6","type":"text","conversion_output":true,"text":"using the SBST; and c) the effect of key psychosocial mediators on primary outcomes.","text_display":" using the SBST; and c) the effect of key psychosocial mediators on primary outcomes.","confidence":0.99853515625,"confidence_rate":0.9999835291504493},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"08efcc91d9894ee78382728707cbca70","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 16","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-17","page":17,"lines":[{"cnt":[[305,249],[814,249],[814,305],[305,305]],"region":{"top_left_x":305,"top_left_y":249,"width":510,"height":57},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2033d2c84f6240c4ad978e1332da4d80","type":"section_header","conversion_output":false,"children_ids":["554e7cac5a324f9d93aeb7f047b33003"],"text":"","text_display":""},{"cnt":[[309,254],[810,254],[810,301],[309,301]],"region":{"top_left_x":309,"top_left_y":253,"width":501,"height":48},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"554e7cac5a324f9d93aeb7f047b33003","type":"text","conversion_output":true,"parent_id":"2033d2c84f6240c4ad978e1332da4d80","text":"1.2 Secondary Objective","text_display":"\n\n\\subsection*{1.2 Secondary Objective}","confidence":1,"confidence_rate":1},{"cnt":[[245,322],[1818,322],[1818,365],[245,365]],"region":{"top_left_x":244,"top_left_y":322,"width":1574,"height":44},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8ced86b4071f48179f6454a80009ddaa","type":"text","conversion_output":true,"text":"IMPLEMENTATION data related to the SMT, SSM, and SMT+SSM interventions will be collected","text_display":"\n\nIMPLEMENTATION data related to the SMT, SSM, and SMT+SSM interventions will be collected","confidence":0.9970722198486328,"confidence_rate":0.9999684728143725},{"cnt":[[245,365],[1828,365],[1828,410],[245,410]],"region":{"top_left_x":244,"top_left_y":365,"width":1585,"height":46},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"44e813402c56480d8bec63e07d7e78cc","type":"text","conversion_output":true,"text":"and described using mixed methods about important influences that could affect future implementation","text_display":" and described using mixed methods about important influences that could affect future implementation","confidence":1,"confidence_rate":1},{"cnt":[[245,408],[1854,408],[1854,453],[245,453]],"region":{"top_left_x":244,"top_left_y":408,"width":1611,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9807e5caedf1472898e16ea6a64af9a4","type":"text","conversion_output":true,"text":"and interpretation of results. \\({ }^{24}\\) Qualitative data will lend context regarding patients', staff, providers' and","text_display":" and interpretation of results. \\({ }^{24}\\) Qualitative data will lend context regarding patients', staff, providers' and","confidence":0.99951171875,"confidence_rate":0.999996123813083},{"cnt":[[245,453],[1704,453],[1704,496],[245,496]],"region":{"top_left_x":244,"top_left_y":453,"width":1460,"height":44},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"46df0074d6f0447fa3f5349063a8537c","type":"text","conversion_output":true,"text":"health system leaders' perceptions of barriers and facilitators associated with the interventions;","text_display":" health system leaders' perceptions of barriers and facilitators associated with the interventions;","confidence":0.99951171875,"confidence_rate":0.9999952582588333},{"cnt":[[245,498],[1798,498],[1798,544],[245,544]],"region":{"top_left_x":244,"top_left_y":498,"width":1555,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4037d8407dfe4d67a02d8a22c692c365","type":"text","conversion_output":true,"text":"quantitative data collection will provide insight into intervention application, adherence, fidelity, and","text_display":" quantitative data collection will provide insight into intervention application, adherence, fidelity, and","confidence":0.99951171875,"confidence_rate":0.9999955600053285},{"cnt":[[245,541],[1790,541],[1790,587],[245,587]],"region":{"top_left_x":244,"top_left_y":541,"width":1546,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"de4a85dce2cd4ebfa5928775e40966b4","type":"text","conversion_output":true,"text":"provider confidence. This will inform the dissemination and implementation plan championed by an","text_display":" provider confidence. This will inform the dissemination and implementation plan championed by an","confidence":1,"confidence_rate":1},{"cnt":[[245,584],[1807,584],[1807,629],[245,629]],"region":{"top_left_x":244,"top_left_y":584,"width":1563,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1a294133c96d4e988ed999b549190df9","type":"text","conversion_output":true,"text":"experienced, multidisciplinary team, uniquely suited to facilitate translation across health professions.","text_display":" experienced, multidisciplinary team, uniquely suited to facilitate translation across health professions.","confidence":1,"confidence_rate":1},{"cnt":[[245,675],[1858,675],[1858,718],[245,718]],"region":{"top_left_x":244,"top_left_y":674,"width":1615,"height":44},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9f45178a8af848a5ace9d09a36831256","type":"text","conversion_output":true,"text":"For implementation, we will gather contextual data using mixed methods to facilitate later translation to","text_display":"\n\nFor implementation, we will gather contextual data using mixed methods to facilitate later translation to","confidence":1,"confidence_rate":1},{"cnt":[[245,718],[1820,718],[1820,763],[245,763]],"region":{"top_left_x":244,"top_left_y":717,"width":1576,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ee14b3ea7e3a478294db7f49712e162b","type":"text","conversion_output":true,"text":"other real-world clinical settings, and aid in the interpretation of trial results. This aim is guided by the","text_display":" other real-world clinical settings, and aid in the interpretation of trial results. This aim is guided by the","confidence":1,"confidence_rate":1},{"cnt":[[245,758],[1876,758],[1876,806],[245,806]],"region":{"top_left_x":244,"top_left_y":758,"width":1632,"height":48},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e002023d571d49dfa3dae297206a863f","type":"text","conversion_output":true,"text":"Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE- AIM) \\({ }^{25}\\) framework. It serves as a","text_display":" Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE- AIM) \\({ }^{25}\\) framework. It serves as a","confidence":1,"confidence_rate":1},{"cnt":[[245,804],[1833,804],[1833,849],[245,849]],"region":{"top_left_x":244,"top_left_y":803,"width":1589,"height":46},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"70de3dcfa1074fa390e8007772398b90","type":"text","conversion_output":true,"text":"complement to PRECIS \\({ }^{26}\\) in providing richer information regarding potentially important influences on","text_display":" complement to PRECIS \\({ }^{26}\\) in providing richer information regarding potentially important influences on","confidence":1,"confidence_rate":1},{"cnt":[[245,849],[1695,849],[1695,896],[245,896]],"region":{"top_left_x":244,"top_left_y":848,"width":1452,"height":48},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"60716c9ec14343fa9aa60ff436abd11f","type":"text","conversion_output":true,"text":"the effectiveness of the intervention from patient, staff, provider, and health system leadership","text_display":" the effectiveness of the intervention from patient, staff, provider, and health system leadership","confidence":1,"confidence_rate":1},{"cnt":[[245,889],[477,889],[477,939],[245,939]],"region":{"top_left_x":244,"top_left_y":889,"width":233,"height":50},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"951ac92750e24ffcb5b69383532ff06f","type":"text","conversion_output":true,"text":"perspectives. \\({ }^{25}\\)","text_display":" perspectives. \\({ }^{25}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,980],[1699,980],[1699,1025],[245,1025]],"region":{"top_left_x":244,"top_left_y":979,"width":1456,"height":46},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c9411322522a4dbc9941990f2fdf6e91","type":"text","conversion_output":true,"text":"The trial will use a two-phased approach. An initial UG3 planning and pilot phase will include","text_display":"\n\nThe trial will use a two-phased approach. An initial UG3 planning and pilot phase will include","confidence":1,"confidence_rate":1},{"cnt":[[245,1025],[1803,1025],[1803,1070],[245,1070]],"region":{"top_left_x":244,"top_left_y":1024,"width":1559,"height":46},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5d314525445644a2a9acb8cb6517ecbc","type":"text","conversion_output":true,"text":"development of the detailed study protocol, the data safety \\& monitoring plan, the Study Accrual and","text_display":" development of the detailed study protocol, the data safety \\& monitoring plan, the Study Accrual and","confidence":1,"confidence_rate":1},{"cnt":[[245,1070],[1854,1070],[1854,1113],[245,1113]],"region":{"top_left_x":244,"top_left_y":1069,"width":1611,"height":44},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"94c13529b1d94bdab476dfaadabfe745","type":"text","conversion_output":true,"text":"Retention Plan, obtaining IRB approval, and training of study staff and providers. In addition, during the","text_display":" Retention Plan, obtaining IRB approval, and training of study staff and providers. In addition, during the","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1708,1113],[1708,1158],[245,1158]],"region":{"top_left_x":244,"top_left_y":1112,"width":1465,"height":47},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"83fe8041f908478a909dd9b95484d3c2","type":"text","conversion_output":true,"text":"UG3 planning and pilot phase 92 participants were enrolled into the trial to assess performance","text_display":" UG3 planning and pilot phase 92 participants were enrolled into the trial to assess performance","confidence":1,"confidence_rate":1},{"cnt":[[245,1156],[1790,1156],[1790,1201],[245,1201]],"region":{"top_left_x":244,"top_left_y":1155,"width":1546,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"10ad0ce209b74ce09c1fdd3120d6d021","type":"text","conversion_output":true,"text":"milestones focused on key areas of recruitment, enrollment, patient intervention adherence, provider","text_display":" milestones focused on key areas of recruitment, enrollment, patient intervention adherence, provider","confidence":1,"confidence_rate":1},{"cnt":[[245,1199],[1858,1199],[1858,1244],[245,1244]],"region":{"top_left_x":244,"top_left_y":1198,"width":1615,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"83103104921b4989af2b2c8aaf785bbd","type":"text","conversion_output":true,"text":"intervention fidelity, and data collection. Criteria for including the 92 participants from the pilot phase as","text_display":" intervention fidelity, and data collection. Criteria for including the 92 participants from the pilot phase as","confidence":1,"confidence_rate":1},{"cnt":[[245,1244],[1760,1244],[1760,1291],[245,1291]],"region":{"top_left_x":244,"top_left_y":1243,"width":1516,"height":49},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cc869d08c2354fc8a4ef5243ef932502","type":"text","conversion_output":true,"text":"part of the total sample size were met, and the subsequent UH3 phase will enroll an additional 908","text_display":" part of the total sample size were met, and the subsequent UH3 phase will enroll an additional 908","confidence":1,"confidence_rate":1},{"cnt":[[245,1289],[1005,1289],[1005,1334],[245,1334]],"region":{"top_left_x":244,"top_left_y":1289,"width":762,"height":46},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"091285553fe24b2698c53133b02d8357","type":"text","conversion_output":true,"text":"participants. 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While preventing chronic pain","text_display":" become one of the most significant public health challenges of our time. While preventing chronic pain","confidence":1,"confidence_rate":1},{"cnt":[[245,1772],[1742,1772],[1742,1815],[245,1815]],"region":{"top_left_x":244,"top_left_y":1772,"width":1499,"height":44},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5eb867acab1f4b72af65fa47829e3aa9","type":"text","conversion_output":true,"text":"could result in huge public health benefits, there has been scant research focused on interventions","text_display":" could result in huge public health benefits, there has been scant research focused on interventions","confidence":1,"confidence_rate":1},{"cnt":[[245,1813],[1549,1813],[1549,1863],[245,1863]],"region":{"top_left_x":244,"top_left_y":1813,"width":1306,"height":50},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"41a98615092247d99c627a14d84c72dc","type":"text","conversion_output":true,"text":"targeting the secondary prevention of pain and the transition from acute to chronic. \\({ }^{30}\\)","text_display":" targeting the secondary prevention of pain and the transition from acute to chronic. \\({ }^{30}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1904],[1790,1904],[1790,1949],[245,1949]],"region":{"top_left_x":244,"top_left_y":1903,"width":1546,"height":46},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8c3b8397a71a468bb5c01e252c9c34c3","type":"text","conversion_output":true,"text":"This research aligns with the National Center for Complementary and Integrative Health's (NCCIH)","text_display":"\n\nThis research aligns with the National Center for Complementary and Integrative Health's (NCCIH)","confidence":1,"confidence_rate":1},{"cnt":[[245,1946],[1858,1946],[1858,1994],[245,1994]],"region":{"top_left_x":244,"top_left_y":1946,"width":1615,"height":48},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9f446ad9d229498ca3d2cd5ef5e444cb","type":"text","conversion_output":true,"text":"Strategic Plan \\(2016{ }^{31}\\) by focusing on the investigation of non-pharmacologic pain management strategies","text_display":" Strategic Plan \\(2016{ }^{31}\\) by focusing on the investigation of non-pharmacologic pain management strategies","confidence":0.9990236759185791,"confidence_rate":0.9999916513083871},{"cnt":[[245,1989],[1794,1989],[1794,2039],[245,2039]],"region":{"top_left_x":244,"top_left_y":1989,"width":1550,"height":50},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6ab8cdf963754ae48af6556a45ea3d67","type":"text","conversion_output":true,"text":"that can improve first-line LBP management, including the reduction of opioid use. Specifically, this","text_display":" that can improve first-line LBP management, including the reduction of opioid use. Specifically, this","confidence":1,"confidence_rate":1},{"cnt":[[245,2037],[1777,2037],[1777,2082],[245,2082]],"region":{"top_left_x":244,"top_left_y":2036,"width":1533,"height":46},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4b4f526ea9674607bf7ac66c3e1c7108","type":"text","conversion_output":true,"text":"large, pragmatic study addresses the secondary prevention of cLBP, the most common chronic pain","text_display":" large, pragmatic study addresses the secondary prevention of cLBP, the most common chronic pain","confidence":1,"confidence_rate":1},{"cnt":[[245,2075],[724,2075],[724,2121],[245,2121]],"region":{"top_left_x":244,"top_left_y":2075,"width":481,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7d5140a5c7224923be4b7e89fda36877","type":"text","conversion_output":true,"text":"condition in American adults. \\({ }^{2}\\)","text_display":" condition in American adults. \\({ }^{2}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,2168],[1882,2168],[1882,2213],[245,2213]],"region":{"top_left_x":244,"top_left_y":2167,"width":1639,"height":46},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0a9436ac72a04fcbbadd14a41dd213cc","type":"text","conversion_output":true,"text":"LBP is one of the most common and burdensome pain conditions worldwide with an estimated \\(40-80 \\%\\) of","text_display":"\n\nLBP is one of the most common and burdensome pain conditions worldwide with an estimated \\(40-80 \\%\\) of","confidence":0.9970703125,"confidence_rate":0.9999723212563202},{"cnt":[[245,2209],[1863,2209],[1863,2258],[245,2258]],"region":{"top_left_x":244,"top_left_y":2208,"width":1619,"height":51},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5c1680f838d2462e98a5eb60b2a1749e","type":"text","conversion_output":true,"text":"adults experiencing LBP at some point in their lives. \\({ }^{3233}\\) LBP related disability has increased an alarming","text_display":" adults experiencing LBP at some point in their lives. \\({ }^{3233}\\) LBP related disability has increased an alarming","confidence":0.8115234375,"confidence_rate":0.9982896445675747},{"cnt":[[245,2254],[1880,2254],[1880,2301],[245,2301]],"region":{"top_left_x":244,"top_left_y":2253,"width":1636,"height":48},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0cb302b32b6c4f5bbca8aee554183b31","type":"text","conversion_output":true,"text":"\\(42 \\%\\) over the past two decades, making it the leading cause of disability globally. \\({ }^{4}\\) Approximately \\(20 \\%\\) of","text_display":" \\(42 \\%\\) over the past two decades, making it the leading cause of disability globally. \\({ }^{4}\\) Approximately \\(20 \\%\\) of","confidence":0.9809904098510742,"confidence_rate":0.9998426960181968},{"cnt":[[245,2299],[1818,2299],[1818,2344],[245,2344]],"region":{"top_left_x":244,"top_left_y":2298,"width":1574,"height":46},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"70a62b17cbd24a1fb80b24ba0afb17ce","type":"text","conversion_output":true,"text":"acute cases will become chronic, \\({ }^{34}\\) and it is these individuals that bear a disproportionate share of LBP","text_display":" acute cases will become chronic, \\({ }^{34}\\) and it is these individuals that bear a disproportionate share of LBP","confidence":0.9980475902557373,"confidence_rate":0.9999837141477775},{"cnt":[[245,2342],[1781,2342],[1781,2391],[245,2391]],"region":{"top_left_x":244,"top_left_y":2341,"width":1538,"height":51},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"42fdceba34c5421aa05adb51e5ca9e47","type":"text","conversion_output":true,"text":"associated burden. \\({ }^{35}\\) Spinal pain accounts for \\(9 \\%\\) of total US healthcare expenditures \\({ }^{8}\\) and costs US","text_display":" associated burden. \\({ }^{35}\\) Spinal pain accounts for \\(9 \\%\\) of total US healthcare expenditures \\({ }^{8}\\) and costs US","confidence":0.9990234375,"confidence_rate":0.9999923669068835},{"cnt":[[245,2385],[1828,2385],[1828,2432],[245,2432]],"region":{"top_left_x":244,"top_left_y":2384,"width":1585,"height":49},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3c1372a2e7ec420d9566057ab83ae9c1","type":"text","conversion_output":true,"text":"employers an estimated \\(\\$ 19.8\\) billion per year due to lost productivity. \\({ }^{36}\\) While there is a wide range of","text_display":" employers an estimated \\(\\$ 19.8\\) billion per year due to lost productivity. \\({ }^{36}\\) While there is a wide range of","confidence":0.98583984375,"confidence_rate":0.9998840606414336},{"cnt":[[245,2428],[1852,2428],[1852,2477],[245,2477]],"region":{"top_left_x":244,"top_left_y":2427,"width":1608,"height":51},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"af668de2fe1c44a8b47f89a19ddec8e2","type":"text","conversion_output":true,"text":"treatments available for LBP, the majority of cases are not optimally managed. \\({ }^{37}\\) There is also a growing","text_display":" treatments available for LBP, the majority of cases are not optimally managed. \\({ }^{37}\\) There is also a growing","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":47,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"a30c95e09ecf4d25b87d368df712bfbf","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 17","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-18","page":18,"lines":[{"cnt":[[245,254],[1800,254],[1800,299],[245,299]],"region":{"top_left_x":244,"top_left_y":253,"width":1557,"height":46},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1383d086c22942ccb139f60d5f77bfdc","type":"text","conversion_output":true,"text":"awareness that primary care physicians are under-trained in pain management, and do not have ready","text_display":"\nawareness that primary care physicians are under-trained in pain management, and do not have ready","confidence":0.998046875,"confidence_rate":0.9999810192594005},{"cnt":[[245,294],[1846,294],[1846,342],[245,342]],"region":{"top_left_x":244,"top_left_y":294,"width":1602,"height":48},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a3db343a79804af889b5738776905b83","type":"text","conversion_output":true,"text":"access to interdisciplinary treatments that could address LBP from a biopsychosocial perspective. \\({ }^{38}\\) This","text_display":" access to interdisciplinary treatments that could address LBP from a biopsychosocial perspective. \\({ }^{38}\\) This","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[1824,339],[1824,387],[245,387]],"region":{"top_left_x":244,"top_left_y":339,"width":1581,"height":48},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4e244312c2cb48cf9dcbccd4537c8c1c","type":"text","conversion_output":true,"text":"is evidenced by the persistent use of marginally effective and potentially harmful therapies that largely","text_display":" is evidenced by the persistent use of marginally effective and potentially harmful therapies that largely","confidence":1,"confidence_rate":1},{"cnt":[[245,385],[1861,385],[1861,432],[245,432]],"region":{"top_left_x":244,"top_left_y":384,"width":1617,"height":48},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b4937a301cd748ef8402e2c6762cc30f","type":"text","conversion_output":true,"text":"ignore the psychosocial aspects of LBP. For example, the use of epidural injections, opioid prescriptions,","text_display":" ignore the psychosocial aspects of LBP. For example, the use of epidural injections, opioid prescriptions,","confidence":1,"confidence_rate":1},{"cnt":[[245,430],[1772,430],[1772,475],[245,475]],"region":{"top_left_x":244,"top_left_y":429,"width":1529,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bddebdbc58584d8a9238636071973b81","type":"text","conversion_output":true,"text":"and spinal surgeries for LBP has doubled over the past decade with little positive impact on patient","text_display":" and spinal surgeries for LBP has doubled over the past decade with little positive impact on patient","confidence":1,"confidence_rate":1},{"cnt":[[245,471],[1871,471],[1871,518],[245,518]],"region":{"top_left_x":244,"top_left_y":470,"width":1628,"height":48},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"90826c3ea2d245b981f37a6f2f399384","type":"text","conversion_output":true,"text":"outcomes. \\({ }^{28}{ }^{39}\\) Of growing concern, is the over reliance on opioids. An estimated \\(40 \\%\\) of LBP patients use","text_display":" outcomes. \\({ }^{28}{ }^{39}\\) Of growing concern, is the over reliance on opioids. An estimated \\(40 \\%\\) of LBP patients use","confidence":0.975597620010376,"confidence_rate":0.9998085063050329},{"cnt":[[245,516],[1837,516],[1837,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1593,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6ff7438ffaf44d939e5bfc81454d5666","type":"text","conversion_output":true,"text":"opioids making them the most commonly prescribed medications for LBP. \\({ }^{3540}\\) This occurs despite LBP","text_display":" opioids making them the most commonly prescribed medications for LBP. \\({ }^{3540}\\) This occurs despite LBP","confidence":0.73095703125,"confidence_rate":0.9972303858252014},{"cnt":[[245,559],[1803,559],[1803,604],[245,604]],"region":{"top_left_x":244,"top_left_y":558,"width":1559,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"04240278a7d34acebba64730074bdf2b","type":"text","conversion_output":true,"text":"guidelines suggesting other pharmacologic and non-pharmacologic treatment options \\({ }^{5}\\) and mounting","text_display":" guidelines suggesting other pharmacologic and non-pharmacologic treatment options \\({ }^{5}\\) and mounting","confidence":1,"confidence_rate":1},{"cnt":[[245,602],[1766,602],[1766,649],[245,649]],"region":{"top_left_x":244,"top_left_y":601,"width":1523,"height":48},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"14d662bb6b40400f9819a3764642bd23","type":"text","conversion_output":true,"text":"recognition of opioid misuse, addiction, and fatal overdose. \\({ }^{6}\\) The recently released AHRQ review \\({ }^{41}\\)","text_display":" recognition of opioid misuse, addiction, and fatal overdose. \\({ }^{6}\\) The recently released AHRQ review \\({ }^{41}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,647],[1751,647],[1751,694],[245,694]],"region":{"top_left_x":244,"top_left_y":646,"width":1507,"height":48},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f4b57644cf6d451aa52f58141ff354f8","type":"text","conversion_output":true,"text":"largely confirmed the main conclusions of previous reviews \\({ }^{42}\\) regarding the benefits and harms of","text_display":" largely confirmed the main conclusions of previous reviews \\({ }^{42}\\) regarding the benefits and harms of","confidence":1,"confidence_rate":1},{"cnt":[[245,692],[1807,692],[1807,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1563,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"da6efe5dfb054f489c15ec5cc41fe14a","type":"text","conversion_output":true,"text":"pharmacologic therapies. For acute or subacute LBP, NSAIDs, opioids, and skeletal muscle relaxants","text_display":" pharmacologic therapies. For acute or subacute LBP, NSAIDs, opioids, and skeletal muscle relaxants","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1880,735],[1880,780],[245,780]],"region":{"top_left_x":244,"top_left_y":734,"width":1636,"height":46},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8d687d3b26be43d6ad069c2ba04b93ca","type":"text","conversion_output":true,"text":"were associated with only small effects for pain compared to placebo; no benefits were found for systemic","text_display":" were associated with only small effects for pain compared to placebo; no benefits were found for systemic","confidence":1,"confidence_rate":1},{"cnt":[[245,780],[1815,780],[1815,827],[245,827]],"region":{"top_left_x":244,"top_left_y":779,"width":1572,"height":49},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"42874643cbef473a82685f2b09703558","type":"text","conversion_output":true,"text":"corticosteroids or acetaminophen (which due to new evidence, differed from previous reviews). There","text_display":" corticosteroids or acetaminophen (which due to new evidence, differed from previous reviews). There","confidence":0.99951171875,"confidence_rate":0.9999953038523912},{"cnt":[[245,825],[1833,825],[1833,870],[245,870]],"region":{"top_left_x":244,"top_left_y":825,"width":1589,"height":46},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"adbcd6727921434f834e5a6489199228","type":"text","conversion_output":true,"text":"was also increased risk of adverse events (AEs) compared to placebo for all pharmacological therapies.","text_display":" was also increased risk of adverse events (AEs) compared to placebo for all pharmacological therapies.","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[1828,911],[1828,956],[245,956]],"region":{"top_left_x":244,"top_left_y":910,"width":1585,"height":47},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c94446861e6d4c4d9e28f1916baf014c","type":"text","conversion_output":true,"text":"The overreliance on ineffective, costly and at times harmful treatments suggests a serious deficiency in","text_display":"\n\nThe overreliance on ineffective, costly and at times harmful treatments suggests a serious deficiency in","confidence":1,"confidence_rate":1},{"cnt":[[245,954],[1815,954],[1815,1001],[245,1001]],"region":{"top_left_x":244,"top_left_y":953,"width":1572,"height":49},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9cfc45c6886948f08f4503fe98f6b759","type":"text","conversion_output":true,"text":"the uptake and translation of research based guidelines. \\({ }^{43-45}\\) The 2017 American College of Physicians","text_display":" the uptake and translation of research based guidelines. \\({ }^{43-45}\\) The 2017 American College of Physicians","confidence":1,"confidence_rate":1},{"cnt":[[245,1001],[1704,1001],[1704,1046],[245,1046]],"region":{"top_left_x":244,"top_left_y":1001,"width":1460,"height":46},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"076d1bf2afd54abd9da0a7cce46961f9","type":"text","conversion_output":true,"text":"LBP guidelines recommended clinicians select non-pharmacologic treatments including spinal","text_display":" LBP guidelines recommended clinicians select non-pharmacologic treatments including spinal","confidence":1,"confidence_rate":1},{"cnt":[[245,1042],[1777,1042],[1777,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1041,"width":1533,"height":49},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"54de83c543cc4d9e90813cd402e97ffa","type":"text","conversion_output":true,"text":"manipulation for acute LBP and consider pharmacological treatment if desired. \\({ }^{46}\\) Poor adherence to","text_display":" manipulation for acute LBP and consider pharmacological treatment if desired. \\({ }^{46}\\) Poor adherence to","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1820,1087],[1820,1132],[245,1132]],"region":{"top_left_x":244,"top_left_y":1087,"width":1576,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34cd5eb8467a48a2beba3c4ab76a9f66","type":"text","conversion_output":true,"text":"research based guidelines is endemic across health professions. \\({ }^{47}\\) There are several barriers to research","text_display":" research based guidelines is endemic across health professions. \\({ }^{47}\\) There are several barriers to research","confidence":1,"confidence_rate":1},{"cnt":[[245,1130],[1755,1130],[1755,1175],[245,1175]],"region":{"top_left_x":244,"top_left_y":1130,"width":1512,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8447a1c808c84def86dca2ad9f346980","type":"text","conversion_output":true,"text":"uptake at physician and health system levels including knowledge deficiencies, \\({ }^{48-50}\\) poorly aligned","text_display":" uptake at physician and health system levels including knowledge deficiencies, \\({ }^{48-50}\\) poorly aligned","confidence":1,"confidence_rate":1},{"cnt":[[245,1173],[1734,1173],[1734,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1173,"width":1490,"height":50},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"30173040edef43289ca0c20ae4a2160b","type":"text","conversion_output":true,"text":"incentives, \\({ }^{51}\\) and organizational factors. \\({ }^{52}{ }^{53}\\) There is also recognition that most research has been","text_display":" incentives, \\({ }^{51}\\) and organizational factors. \\({ }^{52}{ }^{53}\\) There is also recognition that most research has been","confidence":1,"confidence_rate":1},{"cnt":[[245,1216],[1766,1216],[1766,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1523,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d58c6f9dc99e4c32b5c4fb7ac7e26305","type":"text","conversion_output":true,"text":"insufficiently pragmatic to meet the needs of its end-users. \\({ }^{24}\\) To speed the translation of research to","text_display":" insufficiently pragmatic to meet the needs of its end-users. \\({ }^{24}\\) To speed the translation of research to","confidence":1,"confidence_rate":1},{"cnt":[[245,1263],[1732,1263],[1732,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1263,"width":1488,"height":46},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f469dd0ce020453a9691f989775fbc0c","type":"text","conversion_output":true,"text":"practice there has been increasing interest in research designs and strategies that work to balance","text_display":" practice there has been increasing interest in research designs and strategies that work to balance","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1732,1306],[1732,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1306,"width":1488,"height":46},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f8339f1881804648852df0c29705e8ba","type":"text","conversion_output":true,"text":"methodological rigor with generalizability. This includes the emergence of hybrid effectiveness-","text_display":" methodological rigor with generalizability. This includes the emergence of hybrid effectiveness","confidence":1,"confidence_rate":1},{"cnt":[[245,1349],[1837,1349],[1837,1396],[245,1396]],"region":{"top_left_x":244,"top_left_y":1349,"width":1593,"height":48},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2144a18e82934317a1cec6e423586211","type":"text","conversion_output":true,"text":"implementation designs, \\({ }^{24}\\) and other frameworks, \\({ }^{2526}\\) which blend rigorous clinical research approaches","text_display":"implementation designs, \\({ }^{24}\\) and other frameworks, \\({ }^{2526}\\) which blend rigorous clinical research approaches","confidence":0.6869127270765603,"confidence_rate":0.997070330899066},{"cnt":[[245,1394],[1843,1394],[1843,1439],[245,1439]],"region":{"top_left_x":244,"top_left_y":1394,"width":1600,"height":46},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"56c4be0015f546a8885232ffe2573b62","type":"text","conversion_output":true,"text":"alongside implementation research methods to facilitate adoption by providers and systems. While such","text_display":" alongside implementation research methods to facilitate adoption by providers and systems. While such","confidence":0.99853515625,"confidence_rate":0.9999861706835268},{"cnt":[[245,1435],[1848,1435],[1848,1485],[245,1485]],"region":{"top_left_x":244,"top_left_y":1435,"width":1604,"height":50},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a1927dd67fd7416996540ddbb25022cc","type":"text","conversion_output":true,"text":"approaches are gaining traction in other health fields, \\({ }^{54-56}\\) there have been few studies in the LBP arena \\({ }^{57}\\)","text_display":" approaches are gaining traction in other health fields, \\({ }^{54-56}\\) there have been few studies in the LBP arena \\({ }^{57}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1482],[793,1482],[793,1532],[245,1532]],"region":{"top_left_x":244,"top_left_y":1482,"width":549,"height":50},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b07382ebe342459e9f9d96184e3c4b87","type":"text","conversion_output":true,"text":"which have used such an approach.","text_display":" which have used such an approach.","confidence":1,"confidence_rate":1},{"cnt":[[245,1571],[1815,1571],[1815,1618],[245,1618]],"region":{"top_left_x":244,"top_left_y":1570,"width":1572,"height":48},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8cb2c9fe0059405fad89910f4b62e858","type":"text","conversion_output":true,"text":"There is growing evidence that physical and psychosocial risk factors can predict progression of acute","text_display":"\n\nThere is growing evidence that physical and psychosocial risk factors can predict progression of acute","confidence":1,"confidence_rate":1},{"cnt":[[245,1611],[1790,1611],[1790,1661],[245,1661]],"region":{"top_left_x":244,"top_left_y":1611,"width":1546,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"beedbdf4ac024f388f734558ec2c6570","type":"text","conversion_output":true,"text":"LBP to chronic. \\({ }^{3458}\\) This has led to 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This will require the integration of psychosocial interventions with","confidence":1,"confidence_rate":1},{"cnt":[[245,2097],[1863,2097],[1863,2144],[245,2144]],"region":{"top_left_x":244,"top_left_y":2096,"width":1619,"height":49},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dd286002d6ba43b791b72ef41b72e48b","type":"text","conversion_output":true,"text":"traditional biologically based pain management approaches. \\({ }^{60}\\) Physical therapists (PTs) and chiropractors","text_display":" traditional biologically based pain management approaches. \\({ }^{60}\\) Physical therapists (PTs) and chiropractors","confidence":1,"confidence_rate":1},{"cnt":[[245,2140],[1740,2140],[1740,2187],[245,2187]],"region":{"top_left_x":244,"top_left_y":2139,"width":1497,"height":49},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"af2162de3a6542afa502f9863e7419fe","type":"text","conversion_output":true,"text":"(DCs) are the most common providers of non-pharmacologic treatment for LBP in the U.S., with","text_display":" (DCs) are the most common providers of non-pharmacologic treatment for LBP in the U.S., with","confidence":1,"confidence_rate":1},{"cnt":[[245,2183],[1876,2183],[1876,2232],[245,2232]],"region":{"top_left_x":244,"top_left_y":2182,"width":1632,"height":51},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5df5caeef52449dcbad37f6ec73ff742","type":"text","conversion_output":true,"text":"approximately \\(39 \\%\\) of LBP patients seeking treatment from DCs and \\(34 \\%\\) from PTs. \\({ }^{40}\\) Both PTs and DCs","text_display":" approximately \\(39 \\%\\) of LBP patients seeking treatment from DCs and \\(34 \\%\\) from PTs. \\({ }^{40}\\) Both PTs and DCs","confidence":0.9980475902557373,"confidence_rate":0.9999835772930002},{"cnt":[[245,2230],[1837,2230],[1837,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2230,"width":1593,"height":46},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3a6914b033fd4881986ac232f79e863b","type":"text","conversion_output":true,"text":"help patients manage symptoms and aid in the restoration of movement and functional ability. 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project completion and","text_display":" substantially to the design of the study and enhance the likelihood of successful project completion and","confidence":1,"confidence_rate":1},{"cnt":[[247,1113],[617,1113],[617,1149],[247,1149]],"region":{"top_left_x":247,"top_left_y":1112,"width":370,"height":38},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3424767b77bc4f4cb7cec2ea2692fa8c","type":"text","conversion_output":true,"text":"effective dissemination.","text_display":" effective 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Interventions}","confidence":1,"confidence_rate":1},{"cnt":[[247,1246],[1843,1246],[1843,1287],[247,1287]],"region":{"top_left_x":247,"top_left_y":1246,"width":1597,"height":41},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"db61701f81dd42cbafd49ec536b21680","type":"text","conversion_output":true,"text":"The study uses several approaches to enhance the likelihood of advancing LBP research and shifting the","text_display":"\n\nThe study uses several approaches to enhance the likelihood of advancing LBP research and shifting the","confidence":1,"confidence_rate":1},{"cnt":[[247,1289],[1635,1289],[1635,1334],[247,1334]],"region":{"top_left_x":247,"top_left_y":1289,"width":1388,"height":46},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9270cf87fdde496f9f9e3532531fb385","type":"text","conversion_output":true,"text":"sub-optimal management of acute and sub-acute LBP that currently exists in primary care.","text_display":" sub-optimal management of acute and sub-acute LBP that currently exists in primary care.","confidence":1,"confidence_rate":1},{"cnt":[[249,1377],[1850,1377],[1850,1420],[249,1420]],"region":{"top_left_x":249,"top_left_y":1377,"width":1601,"height":44},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e7156be031e2469282125ad141655650","type":"text","conversion_output":true,"text":"1) This study is the first to assess the effectiveness of SMT, SSM and SMT+SSM relative to MC for the","text_display":"\n1) This study is the first to assess the effectiveness of SMT, SSM and SMT+SSM relative to MC for the","confidence":1,"confidence_rate":1},{"cnt":[[249,1422],[982,1422],[982,1463],[249,1463]],"region":{"top_left_x":249,"top_left_y":1422,"width":733,"height":42},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b34a71a776d344b5847bc1692a0702f0","type":"text","conversion_output":true,"text":"secondary prevention of cLBP that is impactful.","text_display":" secondary prevention of cLBP that is impactful.","confidence":1,"confidence_rate":1},{"cnt":[[247,1508],[1770,1508],[1770,1553],[247,1553]],"region":{"top_left_x":247,"top_left_y":1508,"width":1524,"height":46},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"01de42b394c54042a1fefeb00a6a08fe","type":"text","conversion_output":true,"text":"2) The comprehensive quantitative data collection throughout the follow-up year addresses several","text_display":"\n2) The comprehensive quantitative data collection throughout the follow-up year addresses several","confidence":1,"confidence_rate":1},{"cnt":[[247,1551],[1871,1551],[1871,1596],[247,1596]],"region":{"top_left_x":247,"top_left_y":1551,"width":1625,"height":46},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cc70ec3731294041b245614b68c660ff","type":"text","conversion_output":true,"text":"currently unanswered questions regarding the treatment of acute LBP. This includes how SMT, SSM, and","text_display":" currently unanswered questions regarding the treatment of acute LBP. This includes how SMT, SSM, and","confidence":1,"confidence_rate":1},{"cnt":[[247,1594],[1876,1594],[1876,1639],[247,1639]],"region":{"top_left_x":247,"top_left_y":1594,"width":1629,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3aa79101f14946ed8c74a8deb16c2d14","type":"text","conversion_output":true,"text":"SMT+SSM affect time to recovery from acute LBP, the trajectory of pain and disability over time, as well","text_display":" SMT+SSM affect time to recovery from acute LBP, the trajectory of pain and disability over time, as well","confidence":1,"confidence_rate":1},{"cnt":[[247,1641],[1102,1641],[1102,1682],[247,1682]],"region":{"top_left_x":247,"top_left_y":1641,"width":856,"height":42},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"52cd703aacdb4983bd1c29b0a2e9e23d","type":"text","conversion_output":true,"text":"as the effects of and impacts on psychosocial outcomes.","text_display":" as the effects of and impacts on psychosocial outcomes.","confidence":1,"confidence_rate":1},{"cnt":[[247,1727],[1854,1727],[1854,1772],[247,1772]],"region":{"top_left_x":247,"top_left_y":1727,"width":1608,"height":46},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9ac547c7a31b45f6ae1f048736bf5b1d","type":"text","conversion_output":true,"text":"3) We will address both effectiveness and implementation within our trial. We consider this an efficient,","text_display":"\n3) We will address both effectiveness and implementation within our trial. We consider this an efficient,","confidence":1,"confidence_rate":1},{"cnt":[[247,1766],[1876,1766],[1876,1815],[247,1815]],"region":{"top_left_x":247,"top_left_y":1766,"width":1629,"height":50},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9d51d984e5f747369a3dfc84844cf0d2","type":"text","conversion_output":true,"text":"low risk, and potentially high yield tactic, which maintains the rigor required for assessing effectiveness, \\({ }^{26}\\)","text_display":" low risk, and potentially high yield tactic, which maintains the rigor required for assessing effectiveness, \\({ }^{26}\\)","confidence":1,"confidence_rate":1},{"cnt":[[247,1815],[1798,1815],[1798,1858],[247,1858]],"region":{"top_left_x":247,"top_left_y":1815,"width":1552,"height":44},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"858f725c086f455587440acc2972f743","type":"text","conversion_output":true,"text":"while simultaneously adding key contextual information to speed implementation to other real-world","text_display":" while simultaneously adding key contextual information to speed implementation to other real-world","confidence":0.9990236759185791,"confidence_rate":0.9999905165401506},{"cnt":[[247,1856],[402,1856],[402,1901],[247,1901]],"region":{"top_left_x":247,"top_left_y":1856,"width":155,"height":46},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"aad6c0520bb44b9482890789e073f6e2","type":"text","conversion_output":true,"text":"settings. \\({ }^{25}\\)","text_display":" settings. \\({ }^{25}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1946],[1790,1946],[1790,1992],[245,1992]],"region":{"top_left_x":244,"top_left_y":1946,"width":1546,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"47632397cd1a4debba4306e2b234c4f0","type":"text","conversion_output":true,"text":"4) By training both DCs and PTs to deliver SSM (either alone or in combination with SMT) there is","text_display":"\n4) By training both DCs and PTs to deliver SSM (either alone or in combination with SMT) there is","confidence":1,"confidence_rate":1},{"cnt":[[245,1989],[1876,1989],[1876,2035],[245,2035]],"region":{"top_left_x":244,"top_left_y":1989,"width":1632,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2083677d3f4645188adf160d3b64de3f","type":"text","conversion_output":true,"text":"potential for these providers to have a larger and more impactful role in the frontline management of LBP.","text_display":" potential for these providers to have a larger and more impactful role in the frontline management of LBP.","confidence":1,"confidence_rate":1},{"cnt":[[247,2037],[1807,2037],[1807,2080],[247,2080]],"region":{"top_left_x":247,"top_left_y":2036,"width":1560,"height":44},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"82807d75d5a24f018067cd6718ef2185","type":"text","conversion_output":true,"text":"This may shift the current clinical practice paradigm away from an over-reliance on opioids and other","text_display":" This may shift the current clinical practice paradigm away from an over-reliance on opioids and other","confidence":1,"confidence_rate":1},{"cnt":[[245,2080],[1641,2080],[1641,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2079,"width":1398,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ed43c8bbf3524eb188359f5208f68a09","type":"text","conversion_output":true,"text":"marginally effective medications, to accessible and integrated biopsychosocial approaches.","text_display":" marginally effective medications, to accessible and integrated biopsychosocial approaches.","confidence":1,"confidence_rate":1},{"cnt":[[247,2168],[1811,2168],[1811,2211],[247,2211]],"region":{"top_left_x":247,"top_left_y":2167,"width":1565,"height":44},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2988782b126744c4982650bf85f62623","type":"text","conversion_output":true,"text":"5) This study will be the first in the U.S. to involve collaboration between influential researchers from","text_display":"\n5) This study will be the first in the U.S. to involve collaboration between influential researchers from","confidence":0.99951171875,"confidence_rate":0.9999955600053285},{"cnt":[[247,2211],[1863,2211],[1863,2256],[247,2256]],"region":{"top_left_x":247,"top_left_y":2210,"width":1616,"height":46},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"13918da8fa0548b98ee1a362a4df0955","type":"text","conversion_output":true,"text":"medicine, psychology, and all three licensed provider groups of SMT (chiropractic, physical therapy, and","text_display":" medicine, psychology, and all three licensed provider groups of SMT (chiropractic, physical therapy, and","confidence":1,"confidence_rate":1},{"cnt":[[247,2256],[1381,2256],[1381,2301],[247,2301]],"region":{"top_left_x":247,"top_left_y":2255,"width":1135,"height":46},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"14512d48f1404be68ad4c7b83ae7f4f8","type":"text","conversion_output":true,"text":"osteopathy), increasing the likelihood of widespread translational success.","text_display":" osteopathy), increasing the likelihood of widespread translational success.","confidence":1,"confidence_rate":1},{"cnt":[[247,2342],[1772,2342],[1772,2387],[247,2387]],"region":{"top_left_x":247,"top_left_y":2341,"width":1526,"height":46},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0ce552685f16437d99d5dc35d98866c8","type":"text","conversion_output":true,"text":"Spinal manipulation therapy (SMT) is a physical modality used by both DCs and PTs and is well","text_display":"\n\nSpinal manipulation therapy (SMT) is a physical modality used by both DCs and PTs and is well","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[247,2385],[1811,2385],[1811,2430],[247,2430]],"region":{"top_left_x":247,"top_left_y":2384,"width":1565,"height":46},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6c4ff9d12043411b82bcada83e2b170e","type":"text","conversion_output":true,"text":"accepted by patients as indicated by relatively high utilization and patient satisfaction relative to usual","text_display":" accepted by patients as indicated by relatively high utilization and patient satisfaction relative to usual","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1876,2582],[1876,2615],[1504,2615]],"region":{"top_left_x":1503,"top_left_y":2582,"width":373,"height":33},"line":45,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"22a9c8bed7fd47aea15760bf3750ac65","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 19","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-20","page":20,"lines":[{"cnt":[[245,249],[1807,249],[1807,299],[245,299]],"region":{"top_left_x":244,"top_left_y":249,"width":1563,"height":50},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"79e571a3fa9e4d6b8541fcff0a141a20","type":"text","conversion_output":true,"text":"medical care. \\({ }^{95}\\) Further, the American College of Physicians and the American Pain Society highlight","text_display":"\nmedical care. \\({ }^{95}\\) Further, the American College of Physicians and the American Pain Society highlight","confidence":1,"confidence_rate":1},{"cnt":[[245,294],[1704,294],[1704,342],[245,342]],"region":{"top_left_x":244,"top_left_y":294,"width":1460,"height":48},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"478689cbcbef4e93958ac560fe6dd39d","type":"text","conversion_output":true,"text":"SMT as one of the recommended non-pharmacologic therapies for acute and sub-acute LBP. \\({ }^{46}\\)","text_display":" SMT as one of the recommended non-pharmacologic therapies for acute and sub-acute LBP. \\({ }^{46}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,382],[1880,382],[1880,432],[245,432]],"region":{"top_left_x":244,"top_left_y":382,"width":1636,"height":50},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8f79cd2d578543a4b6a41e8e07f32a50","type":"text","conversion_output":true,"text":"The recently released Agency for Health Research and Quality (AHRQ) comparative effectiveness review","text_display":"\n\nThe recently released Agency for Health Research and Quality (AHRQ) comparative effectiveness review","confidence":1,"confidence_rate":1},{"cnt":[[245,425],[1818,425],[1818,475],[245,475]],"region":{"top_left_x":244,"top_left_y":425,"width":1574,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b9adc4edc71943d880e60c99f934661b","type":"text","conversion_output":true,"text":"provides the most up-to-date synthesis of research regarding SMT for acute LBP. \\({ }^{41}\\) This review builds","text_display":" provides the most up-to-date synthesis of research regarding SMT for acute LBP. \\({ }^{41}\\) This review builds","confidence":1,"confidence_rate":1},{"cnt":[[245,471],[1781,471],[1781,518],[245,518]],"region":{"top_left_x":244,"top_left_y":470,"width":1538,"height":48},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3e3684e224ec4f73ace43c3308460358","type":"text","conversion_output":true,"text":"upon a 2012 Cochrane systematic review, \\({ }^{6496-98}\\) plus three additional trials that have been published","text_display":" upon a 2012 Cochrane systematic review, \\({ }^{6496-98}\\) plus three additional trials that have been published","confidence":0.71240234375,"confidence_rate":0.9971543721464},{"cnt":[[245,511],[1828,511],[1828,561],[245,561]],"region":{"top_left_x":244,"top_left_y":511,"width":1585,"height":50},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ace8ceed312d4d1f938ac58bc4720439","type":"text","conversion_output":true,"text":"since. \\({ }^{649798}\\) The AHRQ review found some evidence that SMT is associated with beneficial effects for","text_display":" since. \\({ }^{649798}\\) The AHRQ review found some evidence that SMT is associated with beneficial effects for","confidence":0.99951171875,"confidence_rate":0.9999957530481652},{"cnt":[[245,556],[1790,556],[1790,606],[245,606]],"region":{"top_left_x":244,"top_left_y":556,"width":1546,"height":50},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8be4366c6ec34fb58405e3e6c48f4be0","type":"text","conversion_output":true,"text":"acute LBP compared to sham therapy, no intervention, or usual medical care. \\({ }^{41}\\) Importantly, the side","text_display":" acute LBP compared to sham therapy, no intervention, or usual medical care. \\({ }^{41}\\) Importantly, the side","confidence":1,"confidence_rate":1},{"cnt":[[245,602],[1760,602],[1760,649],[245,649]],"region":{"top_left_x":244,"top_left_y":601,"width":1516,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d94529efb30e4753b020828bd41816db","type":"text","conversion_output":true,"text":"effects associated with SMT are overall benign, with approximately \\(50 \\%\\) of patients reporting one","text_display":" effects associated with SMT are overall benign, with approximately \\(50 \\%\\) of patients reporting one","confidence":0.9970703125,"confidence_rate":0.9999717889802962},{"cnt":[[245,645],[1835,645],[1835,694],[245,694]],"region":{"top_left_x":244,"top_left_y":644,"width":1591,"height":50},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b7e00368011a4f108b2762750dce52d7","type":"text","conversion_output":true,"text":"reaction, most commonly local discomfort which resolves within a day. \\({ }^{99-102}\\) There is stronger evidence","text_display":" reaction, most commonly local discomfort which resolves within a day. \\({ }^{99-102}\\) There is stronger evidence","confidence":1,"confidence_rate":1},{"cnt":[[245,692],[1794,692],[1794,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1550,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5a7bf5121c7443518f2f06fec051b0b1","type":"text","conversion_output":true,"text":"supporting the use of SMT in cLBP populations where patients have more complicated physical and","text_display":" supporting the use of SMT in cLBP populations where patients have more complicated physical and","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1858,735],[1858,782],[245,782]],"region":{"top_left_x":244,"top_left_y":734,"width":1615,"height":49},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"66b4463b5a014884acfca3022f6c26c1","type":"text","conversion_output":true,"text":"psychological phenotypes. \\({ }^{103}\\) This provides a rationale for applying SMT early during the clinical course","text_display":" psychological phenotypes. \\({ }^{103}\\) This provides a rationale for applying SMT early during the clinical course","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1882,778],[1882,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1639,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5aeaa77f9c4e401b83bf5ea475b8868b","type":"text","conversion_output":true,"text":"of patients with increased risk of chronicity based on physical and psychosocial risk factors (e.g., leg pain,","text_display":" of patients with increased risk of chronicity based on physical and psychosocial risk factors (e.g., leg pain,","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1248,821],[1248,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1005,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1765ea789b074739b3a006ee46179077","type":"text","conversion_output":true,"text":"comorbid pain, catastrophizing, fear, anxiety, and depression). \\({ }^{104}\\)","text_display":" comorbid pain, catastrophizing, fear, anxiety, and depression). \\({ }^{104}\\)","confidence":0.99951171875,"confidence_rate":0.9999937384747559},{"cnt":[[245,907],[1807,907],[1807,958],[245,958]],"region":{"top_left_x":244,"top_left_y":906,"width":1563,"height":53},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6fb070b020cd4a5f9c64db94ba547948","type":"text","conversion_output":true,"text":"Overall, SMT's low risk profile and evidence of benefit lend support for it to be better integrated into","text_display":"\n\nOverall, SMT's low risk profile and evidence of benefit lend support for it to be better integrated into","confidence":1,"confidence_rate":1},{"cnt":[[245,954],[1734,954],[1734,1003],[245,1003]],"region":{"top_left_x":244,"top_left_y":953,"width":1490,"height":51},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c9975b57a9f2418f8a261d13115e4b0e","type":"text","conversion_output":true,"text":"primary care settings in an effort to diminish reliance on pharmacologic and other more invasive","text_display":" primary care settings in an effort to diminish reliance on pharmacologic and other more invasive","confidence":1,"confidence_rate":1},{"cnt":[[245,999],[1837,999],[1837,1046],[245,1046]],"region":{"top_left_x":244,"top_left_y":999,"width":1593,"height":48},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8d99c6b0e708466291566e6c40826d77","type":"text","conversion_output":true,"text":"treatments for acute and sub-acute LBP. It is noteworthy that most studies assessing SMT for acute and","text_display":" treatments for acute and sub-acute LBP. It is noteworthy that most studies assessing SMT for acute and","confidence":1,"confidence_rate":1},{"cnt":[[245,1042],[1798,1042],[1798,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1041,"width":1555,"height":49},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4218830179254427929c6a290efbb3d9","type":"text","conversion_output":true,"text":"sub-acute LBP have primarily assessed pain and disability outcomes in the short-term. In light of the","text_display":" sub-acute LBP have primarily assessed pain and disability outcomes in the short-term. In light of the","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1867,1087],[1867,1132],[245,1132]],"region":{"top_left_x":244,"top_left_y":1087,"width":1623,"height":46},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b51233df4051491d85afd9b0bb95885e","type":"text","conversion_output":true,"text":"enormous burden imposed by LBP of longer duration, a more relevant question appears to be, \"Can SMT","text_display":" enormous burden imposed by LBP of longer duration, a more relevant question appears to be, \"Can SMT","confidence":1,"confidence_rate":1},{"cnt":[[245,1130],[1850,1130],[1850,1177],[245,1177]],"region":{"top_left_x":244,"top_left_y":1130,"width":1606,"height":48},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8c24e9da8e5042bc8eb66cb40660294c","type":"text","conversion_output":true,"text":"prevent acute and sub-acute LBP from transitioning to chronic?\" Sufficiently large, adequately powered","text_display":" prevent acute and sub-acute LBP from transitioning to chronic?\" Sufficiently large, adequately powered","confidence":0.99951171875,"confidence_rate":0.9999954355197808},{"cnt":[[245,1173],[1296,1173],[1296,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1173,"width":1052,"height":50},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f85af700cec24ce2a164155b33cf16c9","type":"text","conversion_output":true,"text":"studies are needed to address this very timely and important issue. \\({ }^{96}\\)","text_display":" studies are needed to address this very timely and important issue. \\({ }^{96}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1259],[1800,1259],[1800,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1258,"width":1557,"height":51},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c9714d7f6c2d4148be1539411cd7b1d1","type":"text","conversion_output":true,"text":"Supported Self-management (SSM). Self-management is widely advocated for LBP and other pain","text_display":"\n\nSupported Self-management (SSM). Self-management is widely advocated for LBP and other pain","confidence":1,"confidence_rate":1},{"cnt":[[245,1302],[1813,1302],[1813,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1301,"width":1570,"height":51},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dce60ad5fa1645b88bab26e7bdc4cf58","type":"text","conversion_output":true,"text":"conditions. \\({ }^{15}\\) We have adopted the definition proposed by Carnes et al, \\({ }^{105}\\) which is consistent with the","text_display":" conditions. \\({ }^{15}\\) We have adopted the definition proposed by Carnes et al, \\({ }^{105}\\) which is consistent with the","confidence":1,"confidence_rate":1},{"cnt":[[245,1347],[1833,1347],[1833,1396],[245,1396]],"region":{"top_left_x":244,"top_left_y":1347,"width":1589,"height":50},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"90033536d8374922b0320a6298e8bf99","type":"text","conversion_output":true,"text":"study and application of self-management for other musculoskeletal pain conditions. \\({ }^{106-108}\\) Defined as a","text_display":" study and application of self-management for other musculoskeletal pain conditions. \\({ }^{106-108}\\) Defined as a","confidence":1,"confidence_rate":1},{"cnt":[[245,1392],[1727,1392],[1727,1439],[245,1439]],"region":{"top_left_x":244,"top_left_y":1392,"width":1484,"height":48},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2ec9a33470544727bc0e43176abe3a57","type":"text","conversion_output":true,"text":"structured or semi-structured instructional program, self-management includes multiple, distinct","text_display":" structured or semi-structured instructional program, self-management includes multiple, distinct","confidence":1,"confidence_rate":1},{"cnt":[[245,1435],[1811,1435],[1811,1485],[245,1485]],"region":{"top_left_x":244,"top_left_y":1435,"width":1568,"height":50},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c6e1d8f9cb57481ab1ee97ff3b0809db","type":"text","conversion_output":true,"text":"components aimed at improving patients' ability to effectively care for themselves on a daily basis. \\({ }^{105}\\)","text_display":" components aimed at improving patients' ability to effectively care for themselves on a daily basis. \\({ }^{105}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1482],[1843,1482],[1843,1532],[245,1532]],"region":{"top_left_x":244,"top_left_y":1482,"width":1600,"height":50},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b88eeb563b2049bfbffc9d9793006d34","type":"text","conversion_output":true,"text":"Components can include psychological strategies (e.g., behavioral or cognitive); mind-body approaches","text_display":" Components can include psychological strategies (e.g., behavioral or cognitive); mind-body approaches","confidence":1,"confidence_rate":1},{"cnt":[[245,1525],[1820,1525],[1820,1575],[245,1575]],"region":{"top_left_x":244,"top_left_y":1525,"width":1576,"height":50},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e8fb78a9a10340d0b069b5a6011f4add","type":"text","conversion_output":true,"text":"(including relaxation, meditation or guided imagery); physical activity (e.g., exercise); lifestyle advice","text_display":" (including relaxation, meditation or guided imagery); physical activity (e.g., exercise); lifestyle advice","confidence":1,"confidence_rate":1},{"cnt":[[245,1571],[1811,1571],[1811,1618],[245,1618]],"region":{"top_left_x":244,"top_left_y":1570,"width":1568,"height":48},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ad9cc79d7a5544818559c32aa426abc0","type":"text","conversion_output":true,"text":"(e.g., for sleep, daily activities, social support); and pain education (e.g., pain theories, prognosis, and","text_display":" (e.g., for sleep, daily activities, social support); and pain education (e.g., pain theories, prognosis, and","confidence":0.9990234375,"confidence_rate":0.9999913536688149},{"cnt":[[245,1611],[1800,1611],[1800,1661],[245,1661]],"region":{"top_left_x":244,"top_left_y":1611,"width":1557,"height":50},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"801a384d9fb54657bfe3e8546a21155e","type":"text","conversion_output":true,"text":"pain management tips). \\({ }^{105}\\) While patients recognize the need for self-management strategies for pain,","text_display":" pain management tips). \\({ }^{105}\\) While patients recognize the need for self-management strategies for pain,","confidence":1,"confidence_rate":1},{"cnt":[[245,1659],[1841,1659],[1841,1704],[245,1704]],"region":{"top_left_x":244,"top_left_y":1658,"width":1598,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"563c88294c5c4beb8485c581c78fca09","type":"text","conversion_output":true,"text":"often they need the support and validation of health care providers to initiate and maintain optimal self-","text_display":" often they need the support and validation of health care providers to initiate and maintain optimal self","confidence":1,"confidence_rate":1},{"cnt":[[245,1697],[1867,1697],[1867,1747],[245,1747]],"region":{"top_left_x":244,"top_left_y":1697,"width":1623,"height":50},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"16ac742be945450aafd1d07ba0b3e2ff","type":"text","conversion_output":true,"text":"care. \\({ }^{109}{ }^{110}\\) In light of increasing calls for PTs and DCs to play a larger role in addressing the psychosocial","text_display":"care. \\({ }^{109}{ }^{110}\\) In light of increasing calls for PTs and DCs to play a larger role in addressing the psychosocial","confidence":0.8330078125,"confidence_rate":0.9986167737669608},{"cnt":[[245,1745],[1815,1745],[1815,1792],[245,1792]],"region":{"top_left_x":244,"top_left_y":1744,"width":1572,"height":48},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"afa38e383c7f4733a1b61ccdc6b7051c","type":"text","conversion_output":true,"text":"aspects of LBP, a natural avenue is through structured self-management (SSM), using evidence-based","text_display":" aspects of LBP, a natural avenue is through structured self-management (SSM), using evidence-based","confidence":1,"confidence_rate":1},{"cnt":[[245,1788],[1244,1788],[1244,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1787,"width":1000,"height":50},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"769c3c1d5253420f972788ca5c716d4a","type":"text","conversion_output":true,"text":"behavioral strategies that educate, motivate and support patients.","text_display":" behavioral strategies that educate, motivate and support patients.","confidence":1,"confidence_rate":1},{"cnt":[[245,1876],[1867,1876],[1867,1923],[245,1923]],"region":{"top_left_x":244,"top_left_y":1875,"width":1623,"height":48},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"068661150ee74152b41e24a1b4db47a4","type":"text","conversion_output":true,"text":"The most recent AHRQ review by Chou et al, found psychological/behavioral based strategies, as well as","text_display":"\n\nThe most recent AHRQ review by Chou et al, found psychological/behavioral based strategies, as well as","confidence":1,"confidence_rate":1},{"cnt":[[245,1921],[1755,1921],[1755,1968],[245,1968]],"region":{"top_left_x":244,"top_left_y":1920,"width":1512,"height":48},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5412e248af954d2b82b1883fdf894398","type":"text","conversion_output":true,"text":"psychological approaches with exercise, yielded small to moderate benefits for cLBP; insufficient","text_display":" psychological approaches with exercise, yielded small to moderate benefits for cLBP; insufficient","confidence":1,"confidence_rate":1},{"cnt":[[245,1964],[1807,1964],[1807,2013],[245,2013]],"region":{"top_left_x":244,"top_left_y":1963,"width":1563,"height":51},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b923b01e696d43a984fca11aa18c83f5","type":"text","conversion_output":true,"text":"evidence however was available to determine effects in patients with acute LBP. \\({ }^{41}\\) These findings are","text_display":" evidence however was available to determine effects in patients with acute LBP. \\({ }^{41}\\) These findings are","confidence":0.9970703125,"confidence_rate":0.9999747073247376},{"cnt":[[245,2007],[1755,2007],[1755,2056],[245,2056]],"region":{"top_left_x":244,"top_left_y":2006,"width":1512,"height":51},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bdf19df0fd21458189462370d264ac6d","type":"text","conversion_output":true,"text":"similar to systematic reviews for other chronic musculoskeletal pain conditions which have found","text_display":" similar to systematic reviews for other chronic musculoskeletal pain conditions which have found","confidence":1,"confidence_rate":1},{"cnt":[[245,2050],[1884,2050],[1884,2099],[245,2099]],"region":{"top_left_x":244,"top_left_y":2049,"width":1641,"height":51},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"720dfe7d8b444cde84565a4ebd358b43","type":"text","conversion_output":true,"text":"behavioral based strategies to be beneficial; \\({ }^{111112}\\) importantly, patient education on its own has been found","text_display":" behavioral based strategies to be beneficial; \\({ }^{111112}\\) importantly, patient education on its own has been found","confidence":0.6565961837768555,"confidence_rate":0.9966131187395467},{"cnt":[[245,2093],[1828,2093],[1828,2142],[245,2142]],"region":{"top_left_x":244,"top_left_y":2092,"width":1585,"height":50},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d147537fdce24c06922e3716a6d09fac","type":"text","conversion_output":true,"text":"to be insufficient. \\({ }^{113114}\\) Further, there is some evidence that shorter programs (no longer than 8 weeks),","text_display":" to be insufficient. \\({ }^{113114}\\) Further, there is some evidence that shorter programs (no longer than 8 weeks),","confidence":0.90966796875,"confidence_rate":0.9992367783732127},{"cnt":[[245,2140],[1760,2140],[1760,2189],[245,2189]],"region":{"top_left_x":244,"top_left_y":2139,"width":1516,"height":51},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"eed5440630c744339e644ed89350270f","type":"text","conversion_output":true,"text":"and delivery by health professionals (versus lay persons) are effective. \\({ }^{105}\\) Research has shown that","text_display":" and delivery by health professionals (versus lay persons) are effective. \\({ }^{105}\\) Research has shown that","confidence":1,"confidence_rate":1},{"cnt":[[245,2185],[1867,2185],[1867,2232],[245,2232]],"region":{"top_left_x":244,"top_left_y":2184,"width":1623,"height":49},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"df29b00136864b1db3c1308713192d5a","type":"text","conversion_output":true,"text":"healthcare providers other than psychologists can be trained to confidently deliver SSM programs similar","text_display":" healthcare providers other than psychologists can be trained to confidently deliver SSM programs similar","confidence":1,"confidence_rate":1},{"cnt":[[245,2226],[690,2226],[690,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2225,"width":446,"height":51},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2f7ac77ed6a54209bde40be21048c9aa","type":"text","conversion_output":true,"text":"to the one proposed. \\({ }^{106108115}\\)","text_display":" to the one proposed. \\({ }^{106108115}\\)","confidence":0.9951171875,"confidence_rate":0.9998806224339535},{"cnt":[[245,2316],[1807,2316],[1807,2363],[245,2363]],"region":{"top_left_x":244,"top_left_y":2316,"width":1563,"height":48},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"de6f296d98cb4be497ae1babd6010c6b","type":"text","conversion_output":true,"text":"While most research to date has focused on SSM for chronic pain management, acute suffers are also","text_display":"\n\nWhile most research to date has focused on SSM for chronic pain management, acute suffers are also","confidence":1,"confidence_rate":1},{"cnt":[[245,2359],[1807,2359],[1807,2408],[245,2408]],"region":{"top_left_x":244,"top_left_y":2358,"width":1563,"height":51},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c8f6ab53054949b389666768c8662224","type":"text","conversion_output":true,"text":"likely to benefit from cognitive and behavioral skills for pain management. To this end, a noteworthy","text_display":" likely to benefit from cognitive and behavioral skills for pain management. To this end, a noteworthy","confidence":1,"confidence_rate":1},{"cnt":[[245,2402],[1826,2402],[1826,2451],[245,2451]],"region":{"top_left_x":244,"top_left_y":2401,"width":1583,"height":51},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"717dbb46354d4d88992efe19275d04aa","type":"text","conversion_output":true,"text":"review by Brunner et al, found that a form of cognitive behavioral therapy, is a promising strategy that","text_display":" review by Brunner et al, found that a form of cognitive behavioral therapy, is a promising strategy that","confidence":1,"confidence_rate":1},{"cnt":[[245,2447],[1760,2447],[1760,2496],[245,2496]],"region":{"top_left_x":244,"top_left_y":2447,"width":1516,"height":50},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d020a659fc4048fea5aa5899d3b0bde2","type":"text","conversion_output":true,"text":"can be integrated into ambulatory PT practices for the prevention of cLBP. \\({ }^{61}\\) This suggests that by","text_display":" can be integrated into ambulatory PT practices for the prevention of cLBP. \\({ }^{61}\\) This suggests that by","confidence":0.9980475902557373,"confidence_rate":0.9999828570050077},{"cnt":[[1504,2580],[1882,2580],[1882,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2580,"width":380,"height":39},"line":47,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"d5d1d21127ff4c7ba04113ef016887ab","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 20","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-21","page":21,"lines":[{"cnt":[[245,251],[1811,251],[1811,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1568,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8f0c01b7414a4d9f82d5b7d6994e26f0","type":"text","conversion_output":true,"text":"addressing the very psychosocial factors implicated in pain (e.g., fear avoidance, social isolation, etc.)","text_display":"\naddressing the very psychosocial factors implicated in pain (e.g., fear avoidance, social isolation, etc.)","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1867,296],[1867,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1623,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cca4bbabbdae42fd92db8070b0446e55","type":"text","conversion_output":true,"text":"well-delivered SSM programs for acute and sub-acute LBP patients could play an important role in cLBP","text_display":" well-delivered SSM programs for acute and sub-acute LBP patients could play an important role in cLBP","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[982,339],[982,389],[245,389]],"region":{"top_left_x":244,"top_left_y":339,"width":738,"height":50},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4e75eeb683c74fafa8739f3c549044fc","type":"text","conversion_output":true,"text":"prevention, and therefore warrant further study.","text_display":" prevention, and therefore warrant further study.","confidence":1,"confidence_rate":1},{"cnt":[[245,425],[1841,425],[1841,475],[245,475]],"region":{"top_left_x":244,"top_left_y":425,"width":1598,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e2c6bdb5034b46688ea96219c750770b","type":"text","conversion_output":true,"text":"Rationale for combining SSM and SMT: Consistent with NCCIH's strategic objective to examine the","text_display":"\n\nRationale for combining SSM and SMT: Consistent with NCCIH's strategic objective to examine the","confidence":1,"confidence_rate":1},{"cnt":[[245,471],[1781,471],[1781,518],[245,518]],"region":{"top_left_x":244,"top_left_y":470,"width":1538,"height":48},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e2d5fd309f144d11ba7848a532bae875","type":"text","conversion_output":true,"text":"interactions of non-pharmacologic interventions for additive effects, \\({ }^{31}\\) the research will examine the","text_display":" interactions of non-pharmacologic interventions for additive effects, \\({ }^{31}\\) the research will examine the","confidence":1,"confidence_rate":1},{"cnt":[[245,516],[1824,516],[1824,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1581,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ded4c9cf0ff54ca9912b46d7cf04b1db","type":"text","conversion_output":true,"text":"effectiveness of combining SSM and SMT. Historically, the predominant part of a PT and DC practice","text_display":" effectiveness of combining SSM and SMT. Historically, the predominant part of a PT and DC practice","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1781,559],[1781,604],[245,604]],"region":{"top_left_x":244,"top_left_y":558,"width":1538,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a8d25f4e80d44970a4ae63a8b0ab83fa","type":"text","conversion_output":true,"text":"has focused on the biological or physical aspects of LBP, \\({ }^{60}\\) with a separation of mind and body, and","text_display":" has focused on the biological or physical aspects of LBP, \\({ }^{60}\\) with a separation of mind and body, and","confidence":1,"confidence_rate":1},{"cnt":[[245,602],[1689,602],[1689,649],[245,649]],"region":{"top_left_x":244,"top_left_y":601,"width":1445,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"46ea10b0b9964f9395b4bdf91d2a6164","type":"text","conversion_output":true,"text":"consequently a distinction between physical and psychological treatments. \\({ }^{116117}\\) However, the","text_display":" consequently a distinction between physical and psychological treatments. \\({ }^{116117}\\) However, the","confidence":0.681640625,"confidence_rate":0.9964576528305518},{"cnt":[[245,645],[1807,645],[1807,694],[245,694]],"region":{"top_left_x":244,"top_left_y":644,"width":1563,"height":50},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dd2701eb048344a1837790b1cd130cdc","type":"text","conversion_output":true,"text":"biopsychosocial model suggests a shift away from this dualism. \\({ }^{116}\\) There is an opportunity to advance","text_display":" biopsychosocial model suggests a shift away from this dualism. \\({ }^{116}\\) There is an opportunity to advance","confidence":0.99951171875,"confidence_rate":0.9999957896597419},{"cnt":[[245,692],[1837,692],[1837,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1593,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"51e05462ec9f4edc909a2f7d1b83bbe8","type":"text","conversion_output":true,"text":"LBP care by exploring how PTs and DCs (and others) can play a role in addressing the complex factors","text_display":" LBP care by exploring how PTs and DCs (and others) can play a role in addressing the complex factors","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1811,735],[1811,780],[245,780]],"region":{"top_left_x":244,"top_left_y":734,"width":1568,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"37d62b8da47548d8903c65afae7f44e6","type":"text","conversion_output":true,"text":"implicated in the transition to LBP chronicity. \\({ }^{109110118}\\) As noted above, patients with increased risk of","text_display":" implicated in the transition to LBP chronicity. \\({ }^{109110118}\\) As noted above, patients with increased risk of","confidence":0.9722185134887695,"confidence_rate":0.9997652384635427},{"cnt":[[245,778],[1848,778],[1848,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1604,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8cc83714cff8493d9e2e430d34581338","type":"text","conversion_output":true,"text":"chronicity have different combinations of physical and psychosocial obstacles to recovery. \\({ }^{104}\\) Given that","text_display":" chronicity have different combinations of physical and psychosocial obstacles to recovery. \\({ }^{104}\\) Given that","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1807,821],[1807,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1563,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"54ef19c04a18452dac6323f17061741f","type":"text","conversion_output":true,"text":"SMT and SSM target complementary mechanisms (SMT primarily biological and physical, and SSM","text_display":" SMT and SSM target complementary mechanisms (SMT primarily biological and physical, and SSM","confidence":1,"confidence_rate":1},{"cnt":[[245,868],[1837,868],[1837,913],[245,913]],"region":{"top_left_x":244,"top_left_y":867,"width":1593,"height":47},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c14fb39382804d42982ea8f19d71bf20","type":"text","conversion_output":true,"text":"primarily psychological and social), we anticipate that the combination will promote LBP recovery and","text_display":" primarily psychological and social), we anticipate that the combination will promote LBP recovery and","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[1858,911],[1858,958],[245,958]],"region":{"top_left_x":244,"top_left_y":910,"width":1615,"height":49},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5bcbb654d10746ac858fdda7c4a47818","type":"text","conversion_output":true,"text":"prevent LBP chronicity to a greater degree than usual medical care or either monotherapy alone. Further,","text_display":" prevent LBP chronicity to a greater degree than usual medical care or either monotherapy alone. 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Under the supervision of the data coordinating center no interim","confidence":1,"confidence_rate":1},{"cnt":[[245,1989],[1768,1989],[1768,2039],[245,2039]],"region":{"top_left_x":244,"top_left_y":1989,"width":1525,"height":50},"line":47,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0ec78bea39384c08a32b660255771559","type":"text","conversion_output":true,"text":"analysis was planned or conducted and none of the investigators have had access to outcomes data.","text_display":" analysis was planned or conducted and none of the investigators have had access to outcomes data.","confidence":1,"confidence_rate":1},{"cnt":[[245,2075],[1852,2075],[1852,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2075,"width":1608,"height":50},"line":48,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"67b8eb45981844d0b9b9b10354d4bf02","type":"text","conversion_output":true,"text":"When recruitment in the UG3 phase started in October 2018 we were using the published NIH RTF new","text_display":"\n\nWhen recruitment in the UG3 phase started in October 2018 we were using the published NIH RTF new","confidence":1,"confidence_rate":1},{"cnt":[[245,2121],[1833,2121],[1833,2168],[245,2168]],"region":{"top_left_x":244,"top_left_y":2120,"width":1589,"height":48},"line":49,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9130d144ea264d119a963681638ae0d2","type":"text","conversion_output":true,"text":"definition of chronic LBP: \"a back pain problem that has persisted at least 3 months and has resulted in","text_display":" definition of chronic LBP: \"a back pain problem that has persisted at least 3 months and has resulted 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problem","text_display":" RTF minimum dataset items: 1) LBP duration and 2) proportion of days that LBP has been a problem","confidence":1,"confidence_rate":1},{"cnt":[[245,2247],[1861,2247],[1861,2301],[245,2301]],"region":{"top_left_x":244,"top_left_y":2247,"width":1617,"height":54},"line":52,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4dce2d4e7f5d4b6ba9aeaebcc0abc4b0","type":"text","conversion_output":true,"text":"over the past 6 months. \\({ }^{97}\\) The chronicity status at 12 -month follow-up is based on patients' recall of their","text_display":" over the past 6 months. \\({ }^{97}\\) The chronicity status at 12 -month follow-up is based on patients' recall of their","confidence":0.8892676568357274,"confidence_rate":0.9990976611029851},{"cnt":[[245,2295],[1693,2295],[1693,2344],[245,2344]],"region":{"top_left_x":244,"top_left_y":2294,"width":1449,"height":50},"line":53,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e3bb0e35121742e992b6be32371cd7a3","type":"text","conversion_output":true,"text":"low back pain being present on more or less than half the days during the preceding 6 months.","text_display":" low back pain being present on more or less than half the days during the preceding 6 months.","confidence":1,"confidence_rate":1},{"cnt":[[245,2434],[245,2383],[1798,2385],[1798,2436]],"region":{"top_left_x":244,"top_left_y":2382,"width":1555,"height":55},"line":54,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8e481cb00c6c47b19939738285499056","type":"text","conversion_output":true,"text":"Since the initial approval and funding of our project by NCCIH in August 2017, important published","text_display":"\n\nSince the initial approval and funding of our project by NCCIH in August 2017, important published","confidence":1,"confidence_rate":1},{"cnt":[[245,2428],[1809,2428],[1809,2477],[245,2477]],"region":{"top_left_x":244,"top_left_y":2427,"width":1565,"height":51},"line":55,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3d913dfcc9a54e7aa09bd1f5cf0c2903","type":"text","conversion_output":true,"text":"information has been accumulating regarding the importance of measuring the impact of chronic pain","text_display":" information has been accumulating regarding the importance of measuring the impact of chronic pain","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":56,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"0b1adba378ae40f3ac9f60ebe9b02583","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 23","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-24","page":24,"lines":[{"cnt":[[245,249],[1846,249],[1846,299],[245,299]],"region":{"top_left_x":244,"top_left_y":249,"width":1602,"height":50},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8a6a73d7f77444ccb66a15bb26378c93","type":"text","conversion_output":true,"text":"including chronic LBP \\({ }^{73}\\) (von Korff 2020, Herman 2019, Dahlhamer 2018, Dutmer 2019, Pitcher 2019).","text_display":"\nincluding chronic LBP \\({ }^{73}\\) (von Korff 2020, Herman 2019, Dahlhamer 2018, Dutmer 2019, Pitcher 2019).","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1751,296],[1751,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1507,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e15417880d5a422880fa2ce30e5f70ff","type":"text","conversion_output":true,"text":"This body of literature prompted us to reevaluate the adequacy of our primary chronicity outcome","text_display":" This body of literature prompted us to reevaluate the adequacy of our primary chronicity outcome","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[1846,339],[1846,385],[245,385]],"region":{"top_left_x":244,"top_left_y":339,"width":1602,"height":46},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f51a85041a8d4492917e89fb1f0ffb2b","type":"text","conversion_output":true,"text":"measure. We were aware that the original NIH RTF chronicity outcome measure has several recognized","text_display":" measure. We were aware that the original NIH RTF chronicity outcome measure has several recognized","confidence":1,"confidence_rate":1},{"cnt":[[245,385],[1820,385],[1820,432],[245,432]],"region":{"top_left_x":244,"top_left_y":384,"width":1576,"height":48},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5532978ec11245afb02c7518c769817f","type":"text","conversion_output":true,"text":"limitations: It is a dichotomous outcome that does not incorporate pain severity, pain interference with","text_display":" limitations: It is a dichotomous outcome that does not incorporate pain severity, pain interference with","confidence":1,"confidence_rate":1},{"cnt":[[245,430],[1828,430],[1828,475],[245,475]],"region":{"top_left_x":244,"top_left_y":429,"width":1585,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3133e3732a3444e5b87bc536d5d78a59","type":"text","conversion_output":true,"text":"daily activities, limitations of physical function, and is not able to quantitatively overall LBP impact. It","text_display":" daily activities, limitations of physical function, and is not able to quantitatively overall LBP impact. It","confidence":1,"confidence_rate":1},{"cnt":[[245,473],[1837,473],[1837,518],[245,518]],"region":{"top_left_x":244,"top_left_y":472,"width":1593,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"917a03cf42984f3288e62efe9c87965c","type":"text","conversion_output":true,"text":"also has limited statistical power to conduct pre-specified pairwise comparisons among the four groups.","text_display":" also has limited statistical power to conduct pre-specified pairwise comparisons among the four groups.","confidence":1,"confidence_rate":1},{"cnt":[[245,516],[1833,516],[1833,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1589,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"99d5caf6fb184c8dbd739ef834b7b444","type":"text","conversion_output":true,"text":"To date no data in the literature is available on the prevalence LBP chronicity using the RTF definition.","text_display":" To date no data in the literature is available on the prevalence LBP chronicity using the RTF definition.","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1869,559],[1869,606],[245,606]],"region":{"top_left_x":244,"top_left_y":558,"width":1626,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b19ed7e2efde41aeaefaf6228eb62793","type":"text","conversion_output":true,"text":"The chronicity status at 12-month follow-up based on patients' recall of their low back pain being present","text_display":" The chronicity status at 12-month follow-up based on patients' recall of their low back pain being present","confidence":0.98828125,"confidence_rate":0.9998938078392188},{"cnt":[[245,606],[1257,606],[1257,651],[245,651]],"region":{"top_left_x":244,"top_left_y":605,"width":1013,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3c132bc9bb044d2ab35568230df121fa","type":"text","conversion_output":true,"text":"on more or less than half the days during the preceding 6 months.","text_display":" on more or less than half the days during the preceding 6 months.","confidence":0.99853515625,"confidence_rate":0.9999799191374794},{"cnt":[[245,692],[947,692],[947,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":704,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"db9687e548c14954a0aab3565157bd55","type":"text","conversion_output":true,"text":"References in paragraphs above on this page:","text_display":"\n\nReferences in paragraphs above on this page:","confidence":0.9990234375,"confidence_rate":0.9999800606141427},{"cnt":[[245,735],[1841,735],[1841,780],[245,780]],"region":{"top_left_x":244,"top_left_y":734,"width":1598,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9f9b355da20e431399dce2ba8b0cf73b","type":"text","conversion_output":true,"text":"Dahlhamer 2018 - Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults - United","text_display":"\nDahlhamer 2018 - Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults - United","confidence":0.96142578125,"confidence_rate":0.9996144085994769},{"cnt":[[245,778],[1807,778],[1807,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1563,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c940d8cf7b6b42ccb3ad8081a3fb506c","type":"text","conversion_output":true,"text":"States, 2016. MMWR Dahlhamer J, Lucas J, Zelaya, C, et al. Morb Mortal Wkly Rep 2018;67:1001-","text_display":" States, 2016. MMWR Dahlhamer J, Lucas J, Zelaya, C, et al. 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SPINE: October 15,","text_display":" Clinically Important Change Dutmer, A, Reneman, M, Schiphorst Preuper, H et al. 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The Spine Journal","text_display":" chronic low-back pain study samples Patricia M.Herman, Nicholas Broten et al. The Spine Journal","confidence":1,"confidence_rate":1},{"cnt":[[245,1175],[1053,1175],[1053,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1175,"width":809,"height":48},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"074e2f524dcd4eabbee4ab44772215a1","type":"text","conversion_output":true,"text":"Volume 19, Issue 8, August 2019, Pages 1369-1377","text_display":" Volume 19, Issue 8, August 2019, Pages 1369-1377","confidence":1,"confidence_rate":1},{"cnt":[[245,1261],[1824,1261],[1824,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1261,"width":1581,"height":48},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fb278aeb6bf84e77a87421f778ae7846","type":"text","conversion_output":true,"text":"Pitcher 2019 - Prevalence and profile of high-impact chronic pain in the United States MH Pitcher, M","text_display":"\n\nPitcher 2019 - Prevalence and profile of high-impact chronic pain in the United States MH Pitcher, M","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1871,1306],[1871,1354],[245,1354]],"region":{"top_left_x":244,"top_left_y":1306,"width":1628,"height":48},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3d2423372d3445de9f3abeefd39d0710","type":"text","conversion_output":true,"text":"Von Korff, MC Bushnell, L Porter - The Journal of Pain, 2019 Volume 20, Issue 2, February 2019, Pages","text_display":" Von Korff, MC Bushnell, L Porter - The Journal of Pain, 2019 Volume 20, Issue 2, February 2019, Pages","confidence":1,"confidence_rate":1},{"cnt":[[249,1349],[385,1349],[385,1394],[249,1394]],"region":{"top_left_x":249,"top_left_y":1349,"width":136,"height":46},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ee22e0d4de954483b16acc9a94cecffd","type":"text","conversion_output":true,"text":"146-160","text_display":" 146-160","confidence":1,"confidence_rate":1},{"cnt":[[245,1439],[1803,1439],[1803,1485],[245,1485]],"region":{"top_left_x":244,"top_left_y":1439,"width":1559,"height":46},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"852314b2c9964246b649a88d24062da7","type":"text","conversion_output":true,"text":"Von Korff 2020 - Graded chronic pain scale revised: mild, bothersome, and high impact chronic pain","text_display":"\n\nVon Korff 2020 - Graded chronic pain scale revised: mild, bothersome, and high impact chronic pain","confidence":1,"confidence_rate":1},{"cnt":[[245,1482],[1876,1482],[1876,1528],[245,1528]],"region":{"top_left_x":244,"top_left_y":1482,"width":1632,"height":46},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fbac6a31bb824e52a46d8eb965cfaf03","type":"text","conversion_output":true,"text":"M Von Korff, LL DeBar, EE Krebs, RD Kerns, RA Deyo et al. 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The University of Washington (UWA) will serve as the Data Coordinating Center (DCC).","text_display":" coordination. The University of Washington (UWA) will serve as the Data Coordinating Center (DCC).","confidence":1,"confidence_rate":1},{"cnt":[[245,1833],[1846,1833],[1846,1880],[245,1880]],"region":{"top_left_x":244,"top_left_y":1832,"width":1602,"height":48},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b14209abcbaf4ec086566bbf93943812","type":"text","conversion_output":true,"text":"Screening of potential study candidates and treatment of enrolled participants will be coordinated by the","text_display":" Screening of potential study candidates and treatment of enrolled participants will be coordinated by the","confidence":1,"confidence_rate":1},{"cnt":[[245,1878],[1760,1878],[1760,1925],[245,1925]],"region":{"top_left_x":244,"top_left_y":1877,"width":1516,"height":48},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c0f17048bde041f89c82b1f5ecb5dacf","type":"text","conversion_output":true,"text":"CCCs and will occur at University-affiliated research, outpatient clinics, or virtually using HIPAA","text_display":" CCCs and will occur at University-affiliated research, outpatient clinics, or virtually using HIPAA","confidence":1,"confidence_rate":1},{"cnt":[[245,1921],[518,1921],[518,1970],[245,1970]],"region":{"top_left_x":244,"top_left_y":1920,"width":274,"height":51},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3ad00796063e4d6c9f60fd4143b59263","type":"text","conversion_output":true,"text":"compliant Zoom.","text_display":" compliant Zoom.","confidence":1,"confidence_rate":1},{"cnt":[[241,2007],[771,2007],[771,2056],[241,2056]],"region":{"top_left_x":240,"top_left_y":2006,"width":532,"height":51},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"afcd6e40964f438ca3a940667185836b","type":"section_header","conversion_output":false,"children_ids":["49a7ff87415b47fd9ed8e20551c2960c"],"text":"","text_display":""},{"cnt":[[245,2011],[767,2011],[767,2052],[245,2052]],"region":{"top_left_x":244,"top_left_y":2010,"width":523,"height":42},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"49a7ff87415b47fd9ed8e20551c2960c","type":"text","conversion_output":true,"parent_id":"afcd6e40964f438ca3a940667185836b","text":"3.4 Intervention administration","text_display":"\n\n\\subsection*{3.4 Intervention administration}","confidence":0.9990234375,"confidence_rate":0.9999728603780688},{"cnt":[[245,2054],[1833,2054],[1833,2099],[245,2099]],"region":{"top_left_x":244,"top_left_y":2053,"width":1589,"height":47},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c5d3eaa096ff4728981f3d17d806f511","type":"text","conversion_output":true,"text":"SMT, SSM, and SMT+SSM will be provided by PTs and DCs in Pittsburgh and in Minnesota. Medical","text_display":"\n\nSMT, SSM, and SMT+SSM will be provided by PTs and DCs in Pittsburgh and in Minnesota. Medical","confidence":1,"confidence_rate":1},{"cnt":[[245,2097],[1841,2097],[1841,2144],[245,2144]],"region":{"top_left_x":244,"top_left_y":2096,"width":1598,"height":49},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ae696e8276f74fce987c6d2953faac03","type":"text","conversion_output":true,"text":"providers will provide MC. Since the PTs and DCs will follow the same treatment protocols, there is no","text_display":" providers will provide MC. Since the PTs and DCs will follow the same treatment protocols, there is no","confidence":1,"confidence_rate":1},{"cnt":[[245,2142],[1807,2142],[1807,2189],[245,2189]],"region":{"top_left_x":244,"top_left_y":2141,"width":1563,"height":49},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"210f84647cc346e9822c412fa6158ce1","type":"text","conversion_output":true,"text":"need or plan to assess differences in outcomes based on provider type. The primary goal of SMT is to","text_display":" need or plan to assess differences in outcomes based on provider type. The primary goal of SMT is to","confidence":1,"confidence_rate":1},{"cnt":[[245,2187],[1745,2187],[1745,2232],[245,2232]],"region":{"top_left_x":244,"top_left_y":2187,"width":1501,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"439b0a2f44d84a8a84729478b2f70eaa","type":"text","conversion_output":true,"text":"address the biological and physical aspects of LBP (e.g., spinal dysfunction) with the intention of","text_display":" address the biological and physical aspects of LBP (e.g., spinal dysfunction) with the intention of","confidence":1,"confidence_rate":1},{"cnt":[[245,2230],[1794,2230],[1794,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2230,"width":1550,"height":46},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3f1350bc44a44c6fb8ced453269ada0c","type":"text","conversion_output":true,"text":"restoring maximum movement and functional ability of the spine. The goals of SSM are to primarily","text_display":" restoring maximum movement and functional ability of the spine. The goals of SSM are to primarily","confidence":1,"confidence_rate":1},{"cnt":[[245,2273],[1835,2273],[1835,2318],[245,2318]],"region":{"top_left_x":244,"top_left_y":2273,"width":1591,"height":46},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bdaece9fdecc47bd9551aca8f0ce3c17","type":"text","conversion_output":true,"text":"address the psychosocial aspects of acute and sub-acute LBP, by providing patients the opportunities to","text_display":" address the psychosocial aspects of acute and sub-acute LBP, by providing patients the opportunities to","confidence":1,"confidence_rate":1},{"cnt":[[245,2316],[1869,2316],[1869,2363],[245,2363]],"region":{"top_left_x":244,"top_left_y":2316,"width":1626,"height":48},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4a4fb2d9bc2144bd8b294f64e7e634d1","type":"text","conversion_output":true,"text":"develop their capacity and motivation to self-manage their LBP in an adaptive manner. \\({ }^{108}{ }^{121}\\) The goals of","text_display":" develop their capacity and motivation to self-manage their LBP in an adaptive manner. \\({ }^{108}{ }^{121}\\) The goals of","confidence":0.9239015579223633,"confidence_rate":0.9993769677710481},{"cnt":[[245,2361],[1811,2361],[1811,2408],[245,2408]],"region":{"top_left_x":244,"top_left_y":2361,"width":1568,"height":48},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"97f19d714c0c481983cc99153b9123c1","type":"text","conversion_output":true,"text":"the MC group will be to provide care for acute and subacute LBP using evidence based guidelines for","text_display":" the MC group will be to provide care for acute and subacute LBP using evidence based guidelines for","confidence":1,"confidence_rate":1},{"cnt":[[245,2406],[458,2406],[458,2451],[245,2451]],"region":{"top_left_x":244,"top_left_y":2406,"width":214,"height":46},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7788d7b3bbac4569a267640096f44a43","type":"text","conversion_output":true,"text":"primary care.","text_display":" primary care.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":45,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"d233b7887bd547059c00eac415fcdaec","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 24","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-25","page":25,"lines":[{"cnt":[[241,247],[1025,247],[1025,303],[241,303]],"region":{"top_left_x":240,"top_left_y":247,"width":785,"height":56},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7843ab6198dc46ba8de5052cc81a2451","type":"section_header","conversion_output":false,"children_ids":["47bf163309c24e9eb2a8c802663af73f"],"text":"","text_display":""},{"cnt":[[245,254],[1021,254],[1021,299],[245,299]],"region":{"top_left_x":244,"top_left_y":253,"width":777,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"47bf163309c24e9eb2a8c802663af73f","type":"text","conversion_output":true,"parent_id":"7843ab6198dc46ba8de5052cc81a2451","text":"3.5 Randomization, stratification, and blinding","text_display":"\n\n\\subsection*{3.5 Randomization, stratification, and blinding}","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1850,296],[1850,346],[245,346]],"region":{"top_left_x":244,"top_left_y":296,"width":1606,"height":50},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2dad44ae56ab43168573d274a2fd326f","type":"text","conversion_output":true,"text":"Patients will be randomized to one of the following treatment groups within the \\(2 \\times 2\\) factorial design: (1)","text_display":"\n\nPatients will be randomized to one of the following treatment groups within the \\(2 \\times 2\\) factorial design: (1)","confidence":0.812103271484375,"confidence_rate":0.9981598565131198},{"cnt":[[245,339],[1790,339],[1790,389],[245,389]],"region":{"top_left_x":244,"top_left_y":339,"width":1546,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8a48b0f9ee724ba9a08754f87954c3f7","type":"text","conversion_output":true,"text":"SMT, (2) SSM, (3) the combination of SMT+SSM, or (4) MC. From January 2021 to October 2021,","text_display":" SMT, (2) SSM, (3) the combination of SMT+SSM, or (4) MC. From January 2021 to October 2021,","confidence":1,"confidence_rate":1},{"cnt":[[245,382],[1796,382],[1796,432],[245,432]],"region":{"top_left_x":244,"top_left_y":382,"width":1553,"height":50},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5db526c2077a45db9bc56a72378410d6","type":"text","conversion_output":true,"text":"patients were randomized to remote-delivery of (1) SSM or (2) MC due to the COVID-19 pandemic.","text_display":" patients were randomized to remote-delivery of (1) SSM or (2) MC due to the COVID-19 pandemic.","confidence":1,"confidence_rate":1},{"cnt":[[245,473],[1732,473],[1732,518],[245,518]],"region":{"top_left_x":244,"top_left_y":472,"width":1488,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"086cb4a0a8c84598b5416d9774e6876a","type":"text","conversion_output":true,"text":"The DCC will perform blocked randomization (using variable block sizes of 12 or 16) following","text_display":"\n\nThe DCC will perform blocked randomization (using variable block sizes of 12 or 16) following","confidence":0.8662760257720947,"confidence_rate":0.9985797057645128},{"cnt":[[245,516],[1858,516],[1858,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1615,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"927538abc4b74cae82c64a620b16923f","type":"text","conversion_output":true,"text":"stratification by site and baseline risk for cLBP according to the SBST (medium or high). The computer-","text_display":" stratification by site and baseline risk for cLBP according to the SBST (medium or high). The computer","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1755,559],[1755,608],[245,608]],"region":{"top_left_x":244,"top_left_y":558,"width":1512,"height":51},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"489622f83c334373a8c98bdfab660f18","type":"text","conversion_output":true,"text":"generated random assignments will be conveyed electronically from the DCC to each clinical site.","text_display":"generated random assignments will be conveyed electronically from the DCC to each clinical site.","confidence":1,"confidence_rate":1},{"cnt":[[245,645],[1798,645],[1798,694],[245,694]],"region":{"top_left_x":244,"top_left_y":644,"width":1555,"height":50},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"981402bd46314645b6d05330d63e9eea","type":"text","conversion_output":true,"text":"Blinding of treatment providers and participants is not feasible. However, the following steps will be","text_display":"\n\nBlinding of treatment providers and participants is not feasible. However, the following steps will be","confidence":0.9990234375,"confidence_rate":0.9999908688300274},{"cnt":[[245,692],[1876,692],[1876,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1632,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6bd3fdf137b1404abbf5404ffb0db483","type":"text","conversion_output":true,"text":"taken to minimize potential bias and enhance study rigor: a) all study personnel involved in screening and","text_display":" taken to minimize potential bias and enhance study rigor: a) all study personnel involved in screening and","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1824,735],[1824,782],[245,782]],"region":{"top_left_x":244,"top_left_y":734,"width":1581,"height":49},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2dc4e76ec1fe49f7a6427ff9fdd2f55d","type":"text","conversion_output":true,"text":"enrollment will be masked to upcoming randomization assignments; b) all study personnel involved in","text_display":" enrollment will be masked to upcoming randomization assignments; b) all study personnel involved in","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1876,778],[1876,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1632,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f67eceddcc17471b81a5433de90eb137","type":"text","conversion_output":true,"text":"outcome assessment will be independent of intervention delivery, blinded to intervention arm, and trained","text_display":" outcome assessment will be independent of intervention delivery, blinded to intervention arm, and trained","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1869,821],[1869,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1626,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"902ecbd895634f58b603d9c7eede97ac","type":"text","conversion_output":true,"text":"in ensuring unbiased data collection until after database lock; c) only a single member from the DCC will","text_display":" in ensuring unbiased data collection until after database lock; c) only a single member from the DCC will","confidence":1,"confidence_rate":1},{"cnt":[[245,866],[1820,866],[1820,913],[245,913]],"region":{"top_left_x":244,"top_left_y":865,"width":1576,"height":49},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"abeaf1d7fe3e42539d28acec055cb863","type":"text","conversion_output":true,"text":"be unblinded and have access to treatment group assignment for the purpose of creating closed DSMB","text_display":" be unblinded and have access to treatment group assignment for the purpose of creating closed DSMB","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[1798,911],[1798,960],[245,960]],"region":{"top_left_x":244,"top_left_y":910,"width":1555,"height":51},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"69433f4c7a164aafa2a58314b2471979","type":"text","conversion_output":true,"text":"reports; and d) participants will be queried in self-report questionnaires as to whether or not anybody","text_display":" reports; and d) participants will be queried in self-report questionnaires as to whether or not anybody","confidence":1,"confidence_rate":1},{"cnt":[[245,954],[844,954],[844,1003],[245,1003]],"region":{"top_left_x":244,"top_left_y":953,"width":601,"height":51},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2a534f5878e3464897c31347b6ae9379","type":"text","conversion_output":true,"text":"attempted to influence their responses.","text_display":" attempted to influence their responses.","confidence":1,"confidence_rate":1},{"cnt":[[236,1036],[520,1036],[520,1094],[236,1094]],"region":{"top_left_x":236,"top_left_y":1035,"width":284,"height":59},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7e348fd92d454ebcb8609d26d34f002d","type":"section_header","conversion_output":false,"children_ids":["1d25482ea0aa4314acbe642c8c13d8af"],"text":"","text_display":""},{"cnt":[[245,1042],[513,1042],[513,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1041,"width":270,"height":49},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1d25482ea0aa4314acbe642c8c13d8af","type":"text","conversion_output":true,"parent_id":"7e348fd92d454ebcb8609d26d34f002d","text":"3.6 Trial phases","text_display":"\n\n\\subsection*{3.6 Trial phases}","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1796,1087],[1796,1137],[245,1137]],"region":{"top_left_x":244,"top_left_y":1087,"width":1553,"height":50},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b6f17da84ebb40d3bf4336c60e428887","type":"text","conversion_output":true,"text":"The trial will use a two-phased approach. An initial UG3 planning and pilot phase will include study","text_display":"\n\nThe trial will use a two-phased approach. An initial UG3 planning and pilot phase will include study","confidence":1,"confidence_rate":1},{"cnt":[[245,1130],[1820,1130],[1820,1179],[245,1179]],"region":{"top_left_x":244,"top_left_y":1130,"width":1576,"height":50},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ccb81a91c2cd433594a4613a32e646d8","type":"text","conversion_output":true,"text":"start-up activities including completion of study related documents in collaboration with NCCIH (e.g.,","text_display":" start-up activities including completion of study related documents in collaboration with NCCIH (e.g.,","confidence":1,"confidence_rate":1},{"cnt":[[245,1177],[1824,1177],[1824,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1177,"width":1581,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"16da28a37f8a45eabdf84cf4a45e8951","type":"text","conversion_output":true,"text":"study protocol, data safety \\& monitoring plan), obtaining IRB approval, and training of study staff and","text_display":" study protocol, data safety \\& monitoring plan), obtaining IRB approval, and training of study staff and","confidence":1,"confidence_rate":1},{"cnt":[[245,1216],[1880,1216],[1880,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1636,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"44c4a831bf33439499aa8f0ca16ff690","type":"text","conversion_output":true,"text":"providers. In addition, during the UG3 planning and pilot phase 92 participants were enrolled into the trial","text_display":" providers. 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The milestones and threshold criteria for","text_display":" adherence, provider intervention fidelity, and data collection. 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These include identifying LBP patients at risk for developing cLBP from existing electronic health","text_display":" Plan. 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Additionally, we will","confidence":0.9892578125,"confidence_rate":0.9999018202622116},{"cnt":[[245,2264],[1826,2264],[1826,2314],[245,2314]],"region":{"top_left_x":244,"top_left_y":2264,"width":1583,"height":50},"line":45,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f2a30696c0e8465c8dc6a78948b0367f","type":"text","conversion_output":true,"text":"use print mailings to targeted demographic groups, mass media advertisements (e.g., minority-oriented","text_display":" use print mailings to targeted demographic groups, mass media advertisements (e.g., minority-oriented","confidence":0.99658203125,"confidence_rate":0.9999677003013677},{"cnt":[[245,2312],[1809,2312],[1809,2357],[245,2357]],"region":{"top_left_x":244,"top_left_y":2311,"width":1565,"height":46},"line":46,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"590a8ee35ceb451cb368a55754c49620","type":"text","conversion_output":true,"text":"community newspapers), and we will work with minority leaders and groups in respective cities (e.g.,","text_display":" community newspapers), and we will work with minority leaders and groups in respective cities (e.g.,","confidence":1,"confidence_rate":1},{"cnt":[[245,2355],[1824,2355],[1824,2400],[245,2400]],"region":{"top_left_x":244,"top_left_y":2354,"width":1581,"height":46},"line":47,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a77547e1742a42f9a9be04d5d30944be","type":"text","conversion_output":true,"text":"Urban League, Indian Health Board). 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All participants will","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[922,735],[922,782],[245,782]],"region":{"top_left_x":244,"top_left_y":734,"width":678,"height":49},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b475b391a3c049ffbf4ee51d51eb6ae2","type":"text","conversion_output":true,"text":"provide written consent prior to enrollment.","text_display":" provide written consent prior to enrollment.","confidence":1,"confidence_rate":1},{"cnt":[[241,816],[836,816],[836,874],[241,874]],"region":{"top_left_x":240,"top_left_y":816,"width":596,"height":59},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"93065c79008d4aa8a4d00c6d3ec710a9","type":"section_header","conversion_output":false,"children_ids":["16be78ffff53482c8cf4f1c090a137cc"],"text":"","text_display":""},{"cnt":[[245,821],[831,821],[831,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":588,"height":51},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"16be78ffff53482c8cf4f1c090a137cc","type":"text","conversion_output":true,"parent_id":"93065c79008d4aa8a4d00c6d3ec710a9","text":"4.3.4 Baseline screening procedures","text_display":"\n\n\\subsection*{4.3.4 Baseline screening procedures}","confidence":1,"confidence_rate":1},{"cnt":[[245,868],[1876,868],[1876,913],[245,913]],"region":{"top_left_x":244,"top_left_y":867,"width":1632,"height":47},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ad1e9835515d417290bdd730cca50941","type":"text","conversion_output":true,"text":"Screening consists of a preliminary web-based survey, followed by a phone screen with study staff and an","text_display":"\n\nScreening consists of a preliminary web-based survey, followed by a phone screen with study staff and an","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[810,911],[810,958],[245,958]],"region":{"top_left_x":244,"top_left_y":910,"width":566,"height":49},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f4c3d24d0fbc473cbf8895a7ed8228d5","type":"text","conversion_output":true,"text":"in-person visit to confirm eligibility.","text_display":" in-person visit to confirm eligibility.","confidence":1,"confidence_rate":1},{"cnt":[[236,993],[788,993],[788,1051],[236,1051]],"region":{"top_left_x":236,"top_left_y":992,"width":553,"height":59},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"640236fd9ea6426f8aa043e0d5ce36ad","type":"section_header","conversion_output":false,"children_ids":["dbdc773c269f4bfc97b90d79b87d4e53"],"text":"","text_display":""},{"cnt":[[245,997],[784,997],[784,1046],[245,1046]],"region":{"top_left_x":244,"top_left_y":996,"width":541,"height":51},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dbdc773c269f4bfc97b90d79b87d4e53","type":"text","conversion_output":true,"parent_id":"640236fd9ea6426f8aa043e0d5ce36ad","text":"4.3.5 Randomization procedures","text_display":"\n\n\\subsection*{4.3.5 Randomization procedures}","confidence":1,"confidence_rate":1},{"cnt":[[245,1042],[1830,1042],[1830,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1041,"width":1587,"height":49},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"234d765ed9454084b9ac2a5053f85a0f","type":"text","conversion_output":true,"text":"We will use block randomization within site using variable blocks of size 12 or 16 participants (since 4","text_display":"\n\nWe will use block randomization within site using variable blocks of size 12 or 16 participants (since 4","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1846,1087],[1846,1132],[245,1132]],"region":{"top_left_x":244,"top_left_y":1087,"width":1602,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5b5a3df452a0482bbdedf08a6e311f1a","type":"text","conversion_output":true,"text":"study groups). Using block randomization ensures that equal numbers are randomized to the control and","text_display":" study groups). Using block randomization ensures that equal numbers are randomized to the control and","confidence":1,"confidence_rate":1},{"cnt":[[245,1130],[1725,1130],[1725,1175],[245,1175]],"region":{"top_left_x":244,"top_left_y":1130,"width":1482,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"887b7773b29f4bb19b7325d7c0b7067b","type":"text","conversion_output":true,"text":"intervention arms, and that the intervention groups are balanced at periodic enrollment intervals.","text_display":" intervention arms, and that the intervention groups are balanced at periodic enrollment intervals.","confidence":1,"confidence_rate":1},{"cnt":[[245,1173],[1835,1173],[1835,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1173,"width":1591,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"682cd9e094d341d29bd131e1efb30991","type":"text","conversion_output":true,"text":"Randomization will be stratified on site and on baseline STarT Back screening tool risk status (medium","text_display":"\nRandomization will be stratified on site and on baseline STarT Back screening tool risk status (medium","confidence":1,"confidence_rate":1},{"cnt":[[245,1216],[1833,1216],[1833,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1589,"height":50},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a2954a2c9f5e4ceb8abef71bfad4ccdc","type":"text","conversion_output":true,"text":"risk, or high risk of cLBP). \\({ }^{58104}\\) The study web portal will be available 24 hours a day, 365 days a year,","text_display":" risk, or high risk of cLBP). \\({ }^{58104}\\) The study web portal will be available 24 hours a day, 365 days a year,","confidence":0.6298828125,"confidence_rate":0.9963670758134403},{"cnt":[[245,1263],[1798,1263],[1798,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1263,"width":1555,"height":46},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5069fc67e7c441ca9f0fe04e2e8f5d07","type":"text","conversion_output":true,"text":"for screening and randomization. In the event of planned or unplanned portal downtime, a telephone-","text_display":" for screening and randomization. In the event of planned or unplanned portal downtime, a telephone","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1824,1306],[1824,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1306,"width":1581,"height":46},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"430e6553541549f193f6e3f65fecdb92","type":"text","conversion_output":true,"text":"based backup protocol will be administered by the DCC. From January 2021 to October 2021, patients","text_display":"based backup protocol will be administered by the DCC. From January 2021 to October 2021, patients","confidence":1,"confidence_rate":1},{"cnt":[[245,1349],[1665,1349],[1665,1399],[245,1399]],"region":{"top_left_x":244,"top_left_y":1349,"width":1422,"height":50},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b6d8ccb5b0bc4b01bb2137199c507ff4","type":"text","conversion_output":true,"text":"were randomized to remote-delivery of (1) SSM or (2) MC due to the COVID-19 pandemic.","text_display":" were randomized to remote-delivery of (1) SSM or (2) MC due to the COVID-19 pandemic.","confidence":1,"confidence_rate":1},{"cnt":[[236,1452],[801,1452],[801,1506],[236,1506]],"region":{"top_left_x":236,"top_left_y":1452,"width":566,"height":55},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0ee6f787792a4b46b274d6a467cca04e","type":"section_header","conversion_output":false,"children_ids":["a3f13f25b66646fb91cc02e5393f97a0"],"text":"","text_display":""},{"cnt":[[245,1457],[797,1457],[797,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1456,"width":554,"height":46},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a3f13f25b66646fb91cc02e5393f97a0","type":"text","conversion_output":true,"parent_id":"0ee6f787792a4b46b274d6a467cca04e","text":"5. STUDY INTERVENTIONS","text_display":"\n\n\\section*{5. STUDY INTERVENTIONS}","confidence":1,"confidence_rate":1},{"cnt":[[245,1525],[1848,1525],[1848,1571],[245,1571]],"region":{"top_left_x":244,"top_left_y":1525,"width":1604,"height":46},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b78bddcf5a484666b7d0ad913cf2bc7d","type":"text","conversion_output":true,"text":"Patients will be randomized to one of the following treatment groups within the \\(2 \\times 2\\) factorial design: (1)","text_display":"\n\nPatients will be randomized to one of the following treatment groups within the \\(2 \\times 2\\) factorial design: (1)","confidence":0.91943359375,"confidence_rate":0.9992569358771028},{"cnt":[[245,1568],[1820,1568],[1820,1618],[245,1618]],"region":{"top_left_x":244,"top_left_y":1568,"width":1576,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2afd66b751cf44718d20fb382cbcca89","type":"text","conversion_output":true,"text":"SMT, (2) SSM, (3) the combination of SMT+SSM, or (4) MC. The initial treatment period is 8 weeks.","text_display":" SMT, (2) SSM, (3) the combination of SMT+SSM, or (4) MC. The initial treatment period is 8 weeks.","confidence":0.99951171875,"confidence_rate":0.9999953485775026},{"cnt":[[245,1611],[1865,1611],[1865,1661],[245,1661]],"region":{"top_left_x":244,"top_left_y":1611,"width":1621,"height":50},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"afbb645389c34370be34a580203436e2","type":"text","conversion_output":true,"text":"Decisions regarding visit frequency will be made collaboratively by the provider and patient, as is typical","text_display":" Decisions regarding visit frequency will be made collaboratively by the provider and patient, as is typical","confidence":1,"confidence_rate":1},{"cnt":[[245,1659],[1833,1659],[1833,1704],[245,1704]],"region":{"top_left_x":244,"top_left_y":1658,"width":1589,"height":46},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1349b9319b034df3b976a1d101221533","type":"text","conversion_output":true,"text":"in real-world settings. Participants will be required to attend \\(75 \\%\\) of prescribed intervention visits to be","text_display":" in real-world settings. Participants will be required to attend \\(75 \\%\\) of prescribed intervention visits to be","confidence":0.9990234375,"confidence_rate":0.9999915040391533},{"cnt":[[245,1702],[1734,1702],[1734,1747],[245,1747]],"region":{"top_left_x":244,"top_left_y":1701,"width":1490,"height":46},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"457460970f3f44a29d3995400273ea91","type":"text","conversion_output":true,"text":"considered compliant over the 8 -week period. In addition, participants have the option to receive","text_display":" considered compliant over the 8 -week period. In addition, participants have the option to receive","confidence":0.98681640625,"confidence_rate":0.9998748071886348},{"cnt":[[245,1745],[1815,1745],[1815,1792],[245,1792]],"region":{"top_left_x":244,"top_left_y":1744,"width":1572,"height":48},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dfee6ea5f7d84dfea68ce6b0d386f707","type":"text","conversion_output":true,"text":"additional treatment in the group to which they were randomized if they experience a recurrence of an","text_display":" additional treatment in the group to which they were randomized if they experience a recurrence of an","confidence":1,"confidence_rate":1},{"cnt":[[245,1788],[1880,1788],[1880,1835],[245,1835]],"region":{"top_left_x":244,"top_left_y":1787,"width":1636,"height":48},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f247a26a4ce44351a40de83ebd490ca5","type":"text","conversion_output":true,"text":"acute LBP episode during the 10 month follow-up period. This additional treatment will occur in the same","text_display":" acute LBP episode during the 10 month follow-up period. This additional treatment will occur in the same","confidence":1,"confidence_rate":1},{"cnt":[[245,1833],[1708,1833],[1708,1880],[245,1880]],"region":{"top_left_x":244,"top_left_y":1832,"width":1465,"height":48},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"70f598eddbc144fdbead2a834c27f204","type":"text","conversion_output":true,"text":"study clinic, or virtually using HIPAA compliant Zoom, with the same provider when possible.","text_display":" study clinic, or virtually using HIPAA compliant Zoom, with the same provider when possible.","confidence":1,"confidence_rate":1},{"cnt":[[245,1878],[1766,1878],[1766,1923],[245,1923]],"region":{"top_left_x":244,"top_left_y":1877,"width":1523,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"db9c461cc80d4db2a7d0c953a17ef51c","type":"text","conversion_output":true,"text":"Participants will not be offered the option to receive treatment delivered in any of the other 3 study","text_display":" Participants will not be offered the option to receive treatment delivered in any of the other 3 study","confidence":1,"confidence_rate":1},{"cnt":[[245,1925],[367,1925],[367,1966],[245,1966]],"region":{"top_left_x":244,"top_left_y":1925,"width":124,"height":41},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fead7ad06d564a9aaaeba039334e19e1","type":"text","conversion_output":true,"text":"groups.","text_display":" groups.","confidence":1,"confidence_rate":1},{"cnt":[[245,2007],[1695,2007],[1695,2056],[245,2056]],"region":{"top_left_x":244,"top_left_y":2006,"width":1452,"height":51},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7ef13a944c2745bf9ceffd33c8ae2c3f","type":"text","conversion_output":true,"text":"The primary goal of SMT is to address the biological and physical aspects of LBP (e.g., spinal","text_display":"\n\nThe primary goal of SMT is to address the biological and physical aspects of LBP (e.g., spinal","confidence":1,"confidence_rate":1},{"cnt":[[245,2054],[1852,2054],[1852,2099],[245,2099]],"region":{"top_left_x":244,"top_left_y":2053,"width":1608,"height":47},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8a77c5d8cbba4d7f8c6b29d430d67aee","type":"text","conversion_output":true,"text":"dysfunction) with the intention of restoring maximum movement and functional ability of the spine. The","text_display":" dysfunction) with the intention of restoring maximum movement and functional ability of the spine. The","confidence":1,"confidence_rate":1},{"cnt":[[245,2097],[1865,2097],[1865,2142],[245,2142]],"region":{"top_left_x":244,"top_left_y":2096,"width":1621,"height":46},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5751472a166c44cf8af5e32aa8ad97b5","type":"text","conversion_output":true,"text":"goals of SSM are to primarily address the psychosocial aspects of acute and sub-acute LBP, by providing","text_display":" goals of SSM are to primarily address the psychosocial aspects of acute and sub-acute LBP, by providing","confidence":1,"confidence_rate":1},{"cnt":[[245,2140],[1760,2140],[1760,2185],[245,2185]],"region":{"top_left_x":244,"top_left_y":2139,"width":1516,"height":46},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ec79f61c3bc747f5a91558c8e7b5c819","type":"text","conversion_output":true,"text":"patients' the opportunities to develop their capacity and motivation to self-manage their LBP in an","text_display":" patients' the opportunities to develop their capacity and motivation to self-manage their LBP in an","confidence":1,"confidence_rate":1},{"cnt":[[245,2183],[1867,2183],[1867,2230],[245,2230]],"region":{"top_left_x":244,"top_left_y":2182,"width":1623,"height":49},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fca55551df7a484f9e064b51ea586e65","type":"text","conversion_output":true,"text":"adaptive manner. \\({ }^{45108}\\) The goals of the MC group will be to provide care for acute and subacute LBP as it","text_display":" adaptive manner. \\({ }^{45108}\\) The goals of the MC group will be to provide care for acute and subacute LBP as it","confidence":0.6486330032348633,"confidence_rate":0.9963990971681258},{"cnt":[[245,2228],[1068,2228],[1068,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2227,"width":824,"height":49},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a94c2ddc8a4a483a835255c237d97735","type":"text","conversion_output":true,"text":"would typically be delivered in primary care settings.","text_display":" would typically be delivered in primary care settings.","confidence":1,"confidence_rate":1},{"cnt":[[301,2307],[1240,2307],[1240,2368],[301,2368]],"region":{"top_left_x":300,"top_left_y":2307,"width":940,"height":61},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"60154afb37c04aec958f0a0ffb026f00","type":"section_header","conversion_output":false,"children_ids":["09eba7c3c9b24816a0088b99c33fda0e"],"text":"","text_display":""},{"cnt":[[305,2316],[1235,2316],[1235,2361],[305,2361]],"region":{"top_left_x":305,"top_left_y":2316,"width":931,"height":46},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"09eba7c3c9b24816a0088b99c33fda0e","type":"text","conversion_output":true,"parent_id":"60154afb37c04aec958f0a0ffb026f00","text":"5.1 Interventions, Administration, and Duration","text_display":"\n\n\\subsection*{5.1 Interventions, Administration, and Duration}","confidence":0.9990234375,"confidence_rate":0.9999812109525197},{"cnt":[[236,2376],[932,2376],[932,2436],[236,2436]],"region":{"top_left_x":236,"top_left_y":2376,"width":697,"height":61},"line":47,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2676386dfed54c5395ac780b81e9af3f","type":"section_header","conversion_output":false,"children_ids":["1551df6501d44de88040925336e199d4"],"text":"","text_display":""},{"cnt":[[245,2383],[926,2383],[926,2430],[245,2430]],"region":{"top_left_x":244,"top_left_y":2382,"width":682,"height":48},"line":48,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1551df6501d44de88040925336e199d4","type":"text","conversion_output":true,"parent_id":"2676386dfed54c5395ac780b81e9af3f","text":"5.1.1 Spinal manipulation therapy (SMT)","text_display":"\n\n\\subsection*{5.1.1 Spinal manipulation therapy 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based on those used in the UK BEAM Trial \\({ }^{122}\\) and agreed upon by PT, DC, and","confidence":0.99951171875,"confidence_rate":0.9999956778810385},{"cnt":[[245,296],[1820,296],[1820,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1576,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"af423ed1dced4b26b3756d01c64e6ac9","type":"text","conversion_output":true,"text":"osteopathic professional groups. SMT will be provided by licensed physical therapists (PT-MPT's and","text_display":" osteopathic professional groups. SMT will be provided by licensed physical therapists (PT-MPT's and","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[1863,339],[1863,387],[245,387]],"region":{"top_left_x":244,"top_left_y":339,"width":1619,"height":48},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4cd6e51679bf4a5dab006694d8f10d60","type":"text","conversion_output":true,"text":"DPTs) and licensed doctors of chiropractic (DCs) at the UMN and UPitt who have a minimum of 3 years","text_display":" DPTs) and licensed doctors of chiropractic (DCs) at the UMN and UPitt who have a minimum of 3 years","confidence":1,"confidence_rate":1},{"cnt":[[245,382],[1863,382],[1863,432],[245,432]],"region":{"top_left_x":244,"top_left_y":382,"width":1619,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"220095392a1447c6b045fab27e589860","type":"text","conversion_output":true,"text":"clinical experience. Decisions regarding visit frequency will be made collaboratively by the provider and","text_display":" clinical experience. Decisions regarding visit frequency will be made collaboratively by the provider and","confidence":1,"confidence_rate":1},{"cnt":[[245,430],[1833,430],[1833,475],[245,475]],"region":{"top_left_x":244,"top_left_y":429,"width":1589,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"97fa9aa5f4d74110bbea1b10f1eaa44f","type":"text","conversion_output":true,"text":"patient, as is typical in real-world settings. SMT will be provided within research and outpatient clinics","text_display":" patient, as is typical in real-world settings. SMT will be provided within research and outpatient clinics","confidence":1,"confidence_rate":1},{"cnt":[[245,473],[1783,473],[1783,518],[245,518]],"region":{"top_left_x":244,"top_left_y":472,"width":1540,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fa56ee086f2045659074b8ed0f0c5823","type":"text","conversion_output":true,"text":"affiliated with the UPITT and UMN. Dedicated clinics in Pittsburgh (Physical Therapy Clinical and","text_display":" affiliated with the UPITT and UMN. Dedicated clinics in Pittsburgh (Physical Therapy Clinical and","confidence":1,"confidence_rate":1},{"cnt":[[245,516],[1818,516],[1818,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1574,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d7e64057171c414b9be69efa013ed955","type":"text","conversion_output":true,"text":"Translational Research Center (PT-CTRC) and Homewood Community Engagement Center Wellness","text_display":" Translational Research Center (PT-CTRC) and Homewood Community Engagement Center Wellness","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1850,559],[1850,606],[245,606]],"region":{"top_left_x":244,"top_left_y":558,"width":1606,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6f98b36f79c14e5eb83133e8844965da","type":"text","conversion_output":true,"text":"Pavilion and Minnesota (The Berman Center for Outcomes and Clinical Research and Hennepin County","text_display":" Pavilion and Minnesota (The Berman Center for Outcomes and Clinical Research and Hennepin County","confidence":1,"confidence_rate":1},{"cnt":[[245,604],[1740,604],[1740,649],[245,649]],"region":{"top_left_x":244,"top_left_y":603,"width":1497,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e48a4ac8197f4ea1a8dbfe27e7fdb67a","type":"text","conversion_output":true,"text":"Medical Center Integrative Care Clinic) will function as the main clinics for the trial. In case of a","text_display":" Medical Center Integrative Care Clinic) will function as the main clinics for the trial. In case of a","confidence":1,"confidence_rate":1},{"cnt":[[245,649],[1858,649],[1858,694],[245,694]],"region":{"top_left_x":244,"top_left_y":648,"width":1615,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b92de63bcaef42bb9f94c6c82579efee","type":"text","conversion_output":true,"text":"recurrence of an acute LBP episode during the 10 month follow-up period participants have the option to","text_display":" recurrence of an acute LBP episode during the 10 month follow-up period participants have the option to","confidence":0.99951171875,"confidence_rate":0.9999956000051925},{"cnt":[[245,692],[1807,692],[1807,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1563,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6b6d5a6c68884d15b9f5080da0f8e9bf","type":"text","conversion_output":true,"text":"continue to receive spinal manipulation therapy; this treatment will occur in the study clinics with the","text_display":" continue to receive spinal manipulation therapy; this treatment will occur in the study clinics with the","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1861,735],[1861,782],[245,782]],"region":{"top_left_x":244,"top_left_y":734,"width":1617,"height":49},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8b480d6692e44e55b62d39e47a572e73","type":"text","conversion_output":true,"text":"same provider if possible. They will not be offered the option to receive treatment delivered in any of the","text_display":" same provider if possible. They will not be offered the option to receive treatment delivered in any of the","confidence":1,"confidence_rate":1},{"cnt":[[245,780],[578,780],[578,827],[245,827]],"region":{"top_left_x":244,"top_left_y":779,"width":334,"height":49},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3e8b652618d848359f7e6187650e7a0f","type":"text","conversion_output":true,"text":"other 3 study groups.","text_display":" other 3 study groups.","confidence":1,"confidence_rate":1},{"cnt":[[245,866],[1848,866],[1848,913],[245,913]],"region":{"top_left_x":244,"top_left_y":865,"width":1604,"height":49},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"498462c4fb534671bce2605b50645afc","type":"text","conversion_output":true,"text":"SMT is considered safe for the treatment of LBP, but side effects associated with SMT are common and","text_display":"\n\nSMT is considered safe for the treatment of LBP, but side effects associated with SMT are common and","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[1785,911],[1785,956],[245,956]],"region":{"top_left_x":244,"top_left_y":910,"width":1542,"height":47},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e4f5df11e0ca4120a9b5585126e5f94b","type":"text","conversion_output":true,"text":"benign. Approximately \\(50 \\%\\) of patients report one reaction, most commonly local discomfort which","text_display":" benign. Approximately \\(50 \\%\\) of patients report one reaction, most commonly local discomfort which","confidence":0.9814541339874268,"confidence_rate":0.9998182689725127},{"cnt":[[245,954],[1781,954],[1781,1003],[245,1003]],"region":{"top_left_x":244,"top_left_y":953,"width":1538,"height":51},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1d51b063cc364da596366f972ca5d01e","type":"text","conversion_output":true,"text":"resolves within a day. \\({ }^{799-102}\\) Serious adverse events (SAEs) following lumbar SMT are rare \\({ }^{7}\\) and are","text_display":" resolves within a day. \\({ }^{799-102}\\) Serious adverse events (SAEs) following lumbar SMT are rare \\({ }^{7}\\) and are","confidence":0.86376953125,"confidence_rate":0.9988290917126974},{"cnt":[[245,1001],[1798,999],[1798,1046],[245,1048]],"region":{"top_left_x":244,"top_left_y":998,"width":1555,"height":51},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"be9b93921be44baea5cedc6e74446b01","type":"text","conversion_output":true,"text":"estimated to occur once per million to several million visits and include cauda equina syndrome, disc","text_display":" estimated to occur once per million to several million visits and include cauda equina syndrome, disc","confidence":1,"confidence_rate":1},{"cnt":[[245,1040],[1119,1040],[1119,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1039,"width":876,"height":51},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cebe42c704d24e14bc0a3e9a6e7312b2","type":"text","conversion_output":true,"text":"herniation, fracture, hematomas or hemorrhagic cysts. \\({ }^{123}\\)","text_display":" herniation, fracture, hematomas or hemorrhagic cysts. \\({ }^{123}\\)","confidence":1,"confidence_rate":1},{"cnt":[[236,1123],[922,1120],[922,1182],[236,1184]],"region":{"top_left_x":236,"top_left_y":1120,"width":686,"height":64},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"08a9f0aa605f4d0fb73eaf269941909c","type":"section_header","conversion_output":false,"children_ids":["3e8ef8a65c054c52a36cb987804ce208"],"text":"","text_display":""},{"cnt":[[245,1130],[913,1130],[913,1175],[245,1175]],"region":{"top_left_x":244,"top_left_y":1130,"width":670,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3e8ef8a65c054c52a36cb987804ce208","type":"text","conversion_output":true,"parent_id":"08a9f0aa605f4d0fb73eaf269941909c","text":"5.1.2 Supported self-management (SSM)","text_display":"\n\n\\subsection*{5.1.2 Supported self-management (SSM)}","confidence":1,"confidence_rate":1},{"cnt":[[245,1175],[1779,1175],[1779,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1175,"width":1535,"height":48},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6d8a74f46e9a41e8ae0731ca53eb333e","type":"text","conversion_output":true,"text":"The goals of SSM are to primarily address the psychosocial aspects of acute and sub-acute LBP, by","text_display":"\n\nThe goals of SSM are to primarily address the psychosocial aspects of acute and sub-acute LBP, by","confidence":1,"confidence_rate":1},{"cnt":[[245,1216],[1876,1216],[1876,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1632,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"139e079adfbd40f0a01b83f91c03f579","type":"text","conversion_output":true,"text":"providing patients' the opportunities to develop their capacity and motivation to self-manage their LBP in","text_display":" providing patients' the opportunities to develop their capacity and motivation to self-manage their LBP in","confidence":1,"confidence_rate":1},{"cnt":[[245,1261],[1880,1261],[1880,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1261,"width":1636,"height":48},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"78b6cd8d281b4ec8bd7e8426a3b97654","type":"text","conversion_output":true,"text":"an adaptive manner. \\({ }^{108124}\\) The program is theory informed and evidence based. It is adapted from previous","text_display":" an adaptive manner. \\({ }^{108124}\\) The program is theory informed and evidence based. It is adapted from previous","confidence":0.97705078125,"confidence_rate":0.9998065466180552},{"cnt":[[245,1306],[1871,1306],[1871,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1306,"width":1628,"height":46},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"759b5fd9cc864e31888d059fe5426944","type":"text","conversion_output":true,"text":"SSM programs delivered by PTs, DCs, and other professionals for musculoskeletal and LBP conditions. \\({ }^{11}\\)","text_display":" SSM programs delivered by PTs, DCs, and other professionals for musculoskeletal and LBP conditions. \\({ }^{11}","confidence":1,"confidence_rate":1},{"cnt":[[245,1349],[1876,1349],[1876,1396],[245,1396]],"region":{"top_left_x":244,"top_left_y":1349,"width":1632,"height":48},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cd0d3c3dea6048d8b71847c6f5a961c9","type":"text","conversion_output":true,"text":"\\({ }^{106-108}{ }^{124}\\) SSM will be provided by licensed physical therapists (PT-MPT's and DPTs) and licensed doctors","text_display":" { }^{106-108}{ }^{124}\\) SSM will be provided by licensed physical therapists (PT-MPT's and DPTs) and licensed doctors","confidence":0.9975600242614746,"confidence_rate":0.9999799759600713},{"cnt":[[245,1394],[1871,1394],[1871,1442],[245,1442]],"region":{"top_left_x":244,"top_left_y":1394,"width":1628,"height":48},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"278eec528948480587d0bb394442aeb5","type":"text","conversion_output":true,"text":"of chiropractic (DCs) at the UMN and UPitt who have a minimum of 3 years clinical experience. PTs and","text_display":" of chiropractic (DCs) at the UMN and UPitt who have a minimum of 3 years clinical experience. PTs and","confidence":1,"confidence_rate":1},{"cnt":[[245,1437],[1588,1437],[1588,1485],[245,1485]],"region":{"top_left_x":244,"top_left_y":1437,"width":1344,"height":48},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"30f4e014157a44099ef438f6bdfb11a7","type":"text","conversion_output":true,"text":"DCs will be trained to deliver the SSM program; it includes the following components:","text_display":" DCs will be trained to deliver the SSM program; it includes the following components:","confidence":0.99951171875,"confidence_rate":0.9999945733425232},{"cnt":[[309,1482],[1691,1482],[1691,1532],[309,1532]],"region":{"top_left_x":309,"top_left_y":1482,"width":1382,"height":50},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d685d4533e924d0c85009ea144ab0f7b","type":"text","conversion_output":true,"text":"- Psychological/behavioral strategies (e.g., pleasant activity planning, pacing, cognitive","text_display":"\n- Psychological/behavioral strategies (e.g., pleasant activity planning, pacing, cognitive","confidence":1,"confidence_rate":1},{"cnt":[[370,1525],[866,1525],[866,1575],[370,1575]],"region":{"top_left_x":369,"top_left_y":1525,"width":497,"height":50},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"53a701c4e5d94592aa8d5b067ae0deb2","type":"text","conversion_output":true,"text":"restructuring, problem solving).","text_display":" restructuring, problem solving).","confidence":1,"confidence_rate":1},{"cnt":[[309,1573],[1790,1573],[1790,1618],[309,1618]],"region":{"top_left_x":309,"top_left_y":1572,"width":1481,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"48fd5be7a3ab41e3bdb8733d41bc1a7b","type":"text","conversion_output":true,"text":"- Mind-body approaches (e.g., muscle relaxation, breath awareness, focused attention, guided","text_display":"\n- Mind-body approaches (e.g., muscle relaxation, breath awareness, focused attention, guided","confidence":1,"confidence_rate":1},{"cnt":[[370,1616],[1824,1616],[1824,1663],[370,1663]],"region":{"top_left_x":369,"top_left_y":1615,"width":1456,"height":48},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"defa69aae64d476094d0e151ccb33dfe","type":"text","conversion_output":true,"text":"imagery, simple symptom management, postural awareness and strengthening LBP exercises).","text_display":" imagery, simple symptom management, postural awareness and strengthening LBP exercises).","confidence":1,"confidence_rate":1},{"cnt":[[309,1661],[1528,1661],[1528,1708],[309,1708]],"region":{"top_left_x":309,"top_left_y":1660,"width":1219,"height":49},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0f662f18ac794a4286b8fd6dca4165ae","type":"text","conversion_output":true,"text":"- Lifestyle advice (e.g., sleep, daily activities, prevention of social isolation).","text_display":"\n- Lifestyle advice (e.g., sleep, daily activities, prevention of social isolation).","confidence":1,"confidence_rate":1},{"cnt":[[309,1702],[1790,1702],[1790,1755],[309,1755]],"region":{"top_left_x":309,"top_left_y":1701,"width":1481,"height":55},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4a8386f4865b4a9699e94ef8a47b2209","type":"text","conversion_output":true,"text":"- Pain education (e.g., pain theories, prognosis, and evidence based pain management tips). \\({ }^{105}\\)","text_display":"\n- Pain education (e.g., pain theories, prognosis, and evidence based pain management tips). \\({ }^{105}\\)","confidence":0.9990234375,"confidence_rate":0.9999907826873116},{"cnt":[[245,1792],[1852,1792],[1852,1841],[245,1841]],"region":{"top_left_x":244,"top_left_y":1791,"width":1608,"height":51},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9528db03fd944a85b77fa0adaddc76b6","type":"text","conversion_output":true,"text":"One-on-one sessions, will be provided by licensed PTs and DCs via HIPAA compliant video conference","text_display":"\n\nOne-on-one sessions, will be provided by licensed PTs and DCs via HIPAA compliant video conference","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1841,1835],[1841,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1598,"height":51},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"53a9c36cfbc7423f869c3d08e854ec6c","type":"text","conversion_output":true,"text":"(e.g., Zoom) or at dedicated clinics in Pittsburgh (Physical Therapy Clinical and Translational Research","text_display":" (e.g., Zoom) or at dedicated clinics in Pittsburgh (Physical Therapy Clinical and Translational Research","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1833,1882],[1833,1927],[245,1927]],"region":{"top_left_x":244,"top_left_y":1882,"width":1589,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cad0adff0f984e0da06ea81408976476","type":"text","conversion_output":true,"text":"Center (PT-CTRC) and Homewood Community Engagement Center Wellness Pavilion and Minnesota","text_display":" Center (PT-CTRC) and Homewood Community Engagement Center Wellness Pavilion and Minnesota","confidence":0.9990234375,"confidence_rate":0.9999896060152111},{"cnt":[[245,1925],[1725,1925],[1725,1970],[245,1970]],"region":{"top_left_x":244,"top_left_y":1925,"width":1482,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6bad17e5134e4a8ca93aa0f2b0af4b9c","type":"text","conversion_output":true,"text":"(The Berman Center for Outcomes and Clinical Research and Hennepin County Medical Center","text_display":" (The Berman Center for Outcomes and Clinical Research and Hennepin County Medical Center","confidence":0.99853515625,"confidence_rate":0.9999842375685026},{"cnt":[[245,1968],[1820,1968],[1820,2015],[245,2015]],"region":{"top_left_x":244,"top_left_y":1967,"width":1576,"height":49},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"36177b47874c4e9c95afb54a7323789c","type":"text","conversion_output":true,"text":"Integrative Care Clinic). Session frequency will be decided collaboratively by the provider and patient","text_display":" Integrative Care Clinic). Session frequency will be decided collaboratively by the provider and patient","confidence":1,"confidence_rate":1},{"cnt":[[245,2011],[1807,2011],[1807,2060],[245,2060]],"region":{"top_left_x":244,"top_left_y":2010,"width":1563,"height":51},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"379548d1628c4b9eab2f0a7670ebd4dd","type":"text","conversion_output":true,"text":"depending on the patient's needs and abilities. \\({ }^{107}\\) Informational and instructional materials including,","text_display":" depending on the patient's needs and abilities. \\({ }^{107}\\) Informational and instructional materials including,","confidence":1,"confidence_rate":1},{"cnt":[[245,2056],[1850,2056],[1850,2103],[245,2103]],"region":{"top_left_x":244,"top_left_y":2056,"width":1606,"height":48},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a6ce3cbcbe8a422cb033ad0929e9beb7","type":"text","conversion_output":true,"text":"audio recordings and a workbook (intended for use by patients on their own at their preferred pace) will","text_display":" audio recordings and a workbook (intended for use by patients on their own at their preferred pace) will","confidence":1,"confidence_rate":1},{"cnt":[[245,2097],[483,2097],[483,2146],[245,2146]],"region":{"top_left_x":244,"top_left_y":2096,"width":240,"height":51},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e896867b17a048e8bba289e212b2bcc6","type":"text","conversion_output":true,"text":"be provided. \\({ }^{108}\\)","text_display":" be provided. \\({ }^{108}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,2187],[1867,2187],[1867,2237],[245,2237]],"region":{"top_left_x":244,"top_left_y":2187,"width":1623,"height":50},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d3604a277e5d49ed954e60b9c0001617","type":"text","conversion_output":true,"text":"At the first visit, the PT/DC will provide an overview of the SSM program, and together the clinician and","text_display":"\n\nAt the first visit, the PT/DC will provide an overview of the SSM program, and together the clinician and","confidence":1,"confidence_rate":1},{"cnt":[[245,2230],[1865,2230],[1865,2279],[245,2279]],"region":{"top_left_x":244,"top_left_y":2230,"width":1621,"height":50},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2d93feeb4d414a09aabcd00418f5334b","type":"text","conversion_output":true,"text":"patient will assess which psychological, lifestyle and behavioral strategies would benefit the patient. This","text_display":" patient will assess which psychological, lifestyle and behavioral strategies would benefit the patient. This","confidence":1,"confidence_rate":1},{"cnt":[[245,2277],[1760,2277],[1760,2322],[245,2322]],"region":{"top_left_x":244,"top_left_y":2277,"width":1516,"height":46},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f5ae6dc900c2427ebf376f36512b27e9","type":"text","conversion_output":true,"text":"will be done using a quick, interactive assessment that serves to educate, motivate and develop the","text_display":" will be done using a quick, interactive assessment that serves to educate, motivate and develop the","confidence":1,"confidence_rate":1},{"cnt":[[245,2320],[1833,2320],[1833,2368],[245,2368]],"region":{"top_left_x":244,"top_left_y":2320,"width":1589,"height":48},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1e5fd045fe9d4014970f2d47e1e30cff","type":"text","conversion_output":true,"text":"patient-practitioner bond. The assessment will address common impacts of pain including mood, social","text_display":" patient-practitioner bond. The assessment will address common impacts of pain including mood, social","confidence":1,"confidence_rate":1},{"cnt":[[245,2363],[1871,2363],[1871,2408],[245,2408]],"region":{"top_left_x":244,"top_left_y":2363,"width":1628,"height":46},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"01feb94b13f5492a9aa7a17b276e2cdc","type":"text","conversion_output":true,"text":"connections, relationships, thoughts about LBP and their current situation, activities, sleep and stress. The","text_display":" connections, relationships, thoughts about LBP and their current situation, activities, sleep and stress. The","confidence":1,"confidence_rate":1},{"cnt":[[245,2406],[1867,2406],[1867,2454],[245,2454]],"region":{"top_left_x":244,"top_left_y":2406,"width":1623,"height":48},"line":47,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"50672224ee9f4db6a09296b8db76dbe5","type":"text","conversion_output":true,"text":"PT/DC will also perform a simple and repeated movement assessment (flexion/extension, side gliding) to","text_display":" PT/DC will also perform a simple and repeated movement assessment (flexion/extension, side gliding) to","confidence":1,"confidence_rate":1},{"cnt":[[245,2451],[1869,2451],[1869,2499],[245,2499]],"region":{"top_left_x":244,"top_left_y":2451,"width":1626,"height":48},"line":48,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"73f915e5c5344b5fbd2c0c42880ee839","type":"text","conversion_output":true,"text":"determine if directional preferences exercises (as a form of symptom self-management) would be helpful.","text_display":" determine if directional preferences exercises (as a form of symptom self-management) would be helpful.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":49,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"f31cd7604d744934879299a098baac65","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 32","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-33","page":33,"lines":[{"cnt":[[245,251],[1833,251],[1833,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1589,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bccc6265b85d48e59597e15bf48cd84f","type":"text","conversion_output":true,"text":"If needed, postural awareness exercises (neutral spine, abdominal curl ups, side planks, and quadruped)","text_display":"\n\nIf needed, postural awareness exercises (neutral spine, abdominal curl ups, side planks, and quadruped)","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1794,296],[1794,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1550,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8a5fa18eb3cb4ca4b6e9b082968c09ed","type":"text","conversion_output":true,"text":"will be prescribed to support neutral spine posture, and will include breath awareness to facilitate the","text_display":" will be prescribed to support neutral spine posture, and will include breath awareness to facilitate the","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[1828,339],[1828,387],[245,387]],"region":{"top_left_x":244,"top_left_y":339,"width":1585,"height":48},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5b7f0a1e4ff44948938e6300bd7d2fdb","type":"text","conversion_output":true,"text":"mind-body connection. Strengthening exercises to support daily living (bridging, squats and lunges, all","text_display":" mind-body connection. Strengthening exercises to support daily living (bridging, squats and lunges, all","confidence":1,"confidence_rate":1},{"cnt":[[245,385],[1347,385],[1347,432],[245,432]],"region":{"top_left_x":244,"top_left_y":384,"width":1104,"height":48},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"85d48a66da0846b090ea001217e66907","type":"text","conversion_output":true,"text":"done with 'spine sparing' postures) will also be prescribed if necessary.","text_display":" done with 'spine sparing' postures) will also be prescribed if necessary.","confidence":1,"confidence_rate":1},{"cnt":[[245,473],[1850,473],[1850,518],[245,518]],"region":{"top_left_x":244,"top_left_y":472,"width":1606,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"55cd06fa9144491fbdfbb8376c4e25d7","type":"text","conversion_output":true,"text":"In case of a recurrence of an acute LBP episode during the 10 month follow-up period, participants have","text_display":"\n\nIn case of a recurrence of an acute LBP episode during the 10 month follow-up period, participants have","confidence":1,"confidence_rate":1},{"cnt":[[245,516],[1878,516],[1878,561],[245,561]],"region":{"top_left_x":244,"top_left_y":515,"width":1634,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b405553c476c4de0bc6c9f5964fedf83","type":"text","conversion_output":true,"text":"the option to continue to receive the supported self-management treatment; this treatment will occur in the","text_display":" the option to continue to receive the supported self-management treatment; this treatment will occur in the","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1841,559],[1841,606],[245,606]],"region":{"top_left_x":244,"top_left_y":558,"width":1598,"height":48},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5ea52c3d38ba4a7eb931e3adb64b3bfa","type":"text","conversion_output":true,"text":"study clinics with the same provider if possible. They will not be offered the option to receive treatment","text_display":" study clinics with the same provider if possible. They will not be offered the option to receive treatment","confidence":1,"confidence_rate":1},{"cnt":[[245,604],[930,604],[930,651],[245,651]],"region":{"top_left_x":244,"top_left_y":603,"width":687,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d37bd0b4190d415299ebe12dcc4bf596","type":"text","conversion_output":true,"text":"delivered in any of the other 3 study groups.","text_display":" delivered in any of the other 3 study groups.","confidence":0.994140625,"confidence_rate":0.9998891267414415},{"cnt":[[245,692],[1850,692],[1850,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1606,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0ab7da86ff274e76a9f1b117ade41035","type":"text","conversion_output":true,"text":"Side-Effects: Risks associated with the supported self-management group are considered extremely rare.","text_display":"\n\nSide-Effects: Risks associated with the supported self-management group are considered extremely rare.","confidence":1,"confidence_rate":1},{"cnt":[[245,733],[1725,733],[1725,780],[245,780]],"region":{"top_left_x":244,"top_left_y":732,"width":1482,"height":48},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"930ff9be84134c32a382df0b030a091b","type":"text","conversion_output":true,"text":"No SAEs were reported in trials including physical and biopsychosocial treatment components. \\({ }^{7}\\)","text_display":" No SAEs were reported in trials including physical and biopsychosocial treatment components. \\({ }^{7}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1861,778],[1861,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1617,"height":51},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d9e63c24a7b64071874025f2e3efac27","type":"text","conversion_output":true,"text":"Participants may experience emotional discomfort as a result of discussing the impacts of their pain (e.g.,","text_display":" Participants may experience emotional discomfort as a result of discussing the impacts of their pain (e.g.,","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1820,821],[1820,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1576,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ee2618614bb942f49d4abbb88eeab815","type":"text","conversion_output":true,"text":"mood, social connections, etc.). Participants may also experience physical discomfort as a result of the","text_display":" mood, social connections, etc.). Participants may also experience physical discomfort as a result of the","confidence":1,"confidence_rate":1},{"cnt":[[245,868],[1777,868],[1777,913],[245,913]],"region":{"top_left_x":244,"top_left_y":867,"width":1533,"height":47},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"18d69c68af1048dea9ae15a3f294023b","type":"text","conversion_output":true,"text":"directional preference, postural awareness, and strengthening exercises. All of these side effects are","text_display":" directional preference, postural awareness, and strengthening exercises. All of these side effects are","confidence":1,"confidence_rate":1},{"cnt":[[245,911],[917,911],[917,958],[245,958]],"region":{"top_left_x":244,"top_left_y":910,"width":674,"height":49},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"afc9f01841c5447191f2600b779a2bbf","type":"text","conversion_output":true,"text":"expected to be temporary and short-lasting.","text_display":" expected to be temporary and short-lasting.","confidence":1,"confidence_rate":1},{"cnt":[[241,993],[767,993],[767,1046],[241,1046]],"region":{"top_left_x":240,"top_left_y":992,"width":527,"height":55},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b8a05ae2e563414e8683dfc20b45e0a9","type":"section_header","conversion_output":false,"children_ids":["90705af2b3224dcaab3a9953a9afb9de"],"text":"","text_display":""},{"cnt":[[245,999],[763,999],[763,1038],[245,1038]],"region":{"top_left_x":244,"top_left_y":999,"width":519,"height":39},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"90705af2b3224dcaab3a9953a9afb9de","type":"text","conversion_output":true,"parent_id":"b8a05ae2e563414e8683dfc20b45e0a9","text":"5.1.3 Combined SMT and SSM","text_display":"\n\n\\subsection*{5.1.3 Combined SMT and SSM}","confidence":1,"confidence_rate":1},{"cnt":[[245,1044],[1794,1044],[1794,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1044,"width":1550,"height":46},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"518fce66c4f942c2beb837dce84c879e","type":"text","conversion_output":true,"text":"The goals of the combined SMT+SSM group are to address the biological/physical and psychosocial","text_display":"\n\nThe goals of the combined SMT+SSM group are to address the biological/physical and psychosocial","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1811,1087],[1811,1132],[245,1132]],"region":{"top_left_x":244,"top_left_y":1087,"width":1568,"height":46},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"791e5e70db9f4811adb3781699f0772b","type":"text","conversion_output":true,"text":"components of LBP in an accessible and integrated manner. Delivery of SMT and SSM will be by the","text_display":" components of LBP in an accessible and integrated manner. Delivery of SMT and SSM will be by the","confidence":0.9931640625,"confidence_rate":0.9999320873601193},{"cnt":[[245,1130],[1854,1130],[1854,1175],[245,1175]],"region":{"top_left_x":244,"top_left_y":1130,"width":1611,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a67478e1ce1a4d4781dc28f3a2af5934","type":"text","conversion_output":true,"text":"same provider (licensed PTs or DCs) over an 8-week period using the protocols described above. In case","text_display":" same provider (licensed PTs or DCs) over an 8-week period using the protocols described above. In case","confidence":0.982421875,"confidence_rate":0.9998342711650103},{"cnt":[[245,1175],[1781,1175],[1781,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1175,"width":1538,"height":48},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"016611fa69ee4a67a48eb23446322b79","type":"text","conversion_output":true,"text":"of a recurrence of an acute LBP episode during the 10 month follow-up period participants have the","text_display":" of a recurrence of an acute LBP episode during the 10 month follow-up period participants have the","confidence":0.99951171875,"confidence_rate":0.9999953924587458},{"cnt":[[245,1265],[245,1216],[1760,1218],[1760,1267]],"region":{"top_left_x":244,"top_left_y":1215,"width":1516,"height":53},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a149bab6b34f4bb39aede5c958c48454","type":"text","conversion_output":true,"text":"option to continue to receive this combined treatment; this treatment will occur in the study clinics","text_display":" option to continue to receive this combined treatment; this treatment will occur in the study clinics","confidence":1,"confidence_rate":1},{"cnt":[[245,1261],[1841,1261],[1841,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1261,"width":1598,"height":48},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6508e56675a34c258cd75f42edb52f09","type":"text","conversion_output":true,"text":"(Physical Therapy Clinical and Translational Research Center (PT-CTRC) and Homewood Community","text_display":" (Physical Therapy Clinical and Translational Research Center (PT-CTRC) and Homewood Community","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1815,1306],[1815,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1306,"width":1572,"height":46},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6caf02ec239a4f0ea5039e7c5330b9e7","type":"text","conversion_output":true,"text":"Engagement Center Wellness Pavilion and Minnesota (The Berman Center for Outcomes and Clinical","text_display":" Engagement Center Wellness Pavilion and Minnesota (The Berman Center for Outcomes and Clinical","confidence":1,"confidence_rate":1},{"cnt":[[245,1349],[1766,1349],[1766,1396],[245,1396]],"region":{"top_left_x":244,"top_left_y":1349,"width":1523,"height":48},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"99b7a87e31a74979ae61973c6c29f7b7","type":"text","conversion_output":true,"text":"Research and Hennepin County Medical Center Integrative Care Clinic), or virtually using HIPAA","text_display":" Research and Hennepin County Medical Center Integrative Care Clinic), or virtually using HIPAA","confidence":0.99951171875,"confidence_rate":0.9999950666738041},{"cnt":[[245,1394],[1824,1394],[1824,1439],[245,1439]],"region":{"top_left_x":244,"top_left_y":1394,"width":1581,"height":46},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"582c101a38bf4770ae9391cd41cc85b1","type":"text","conversion_output":true,"text":"compliant Zoom, with the same provider if possible. Trial participants will not be offered the option to","text_display":" compliant Zoom, with the same provider if possible. Trial participants will not be offered the option to","confidence":1,"confidence_rate":1},{"cnt":[[245,1439],[1803,1439],[1803,1485],[245,1485]],"region":{"top_left_x":244,"top_left_y":1439,"width":1559,"height":46},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e5ede0ac0c234d418148949e3d364a9b","type":"text","conversion_output":true,"text":"receive treatment delivered in any of the other 3 study groups. Descriptions of these interventions are","text_display":" receive treatment delivered in any of the other 3 study groups. Descriptions of these interventions are","confidence":1,"confidence_rate":1},{"cnt":[[245,1482],[509,1482],[509,1523],[245,1523]],"region":{"top_left_x":244,"top_left_y":1482,"width":266,"height":42},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"92d07d34671a47ea8a4ab765ff21e7c2","type":"text","conversion_output":true,"text":"described above.","text_display":" described above.","confidence":1,"confidence_rate":1},{"cnt":[[241,1564],[556,1564],[556,1618],[241,1618]],"region":{"top_left_x":240,"top_left_y":1564,"width":317,"height":54},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e92a8e9873fa46618ff04f3c79ca84f5","type":"section_header","conversion_output":false,"children_ids":["12da315ab7b34067b18c257f71d01050"],"text":"","text_display":""},{"cnt":[[245,1573],[552,1573],[552,1609],[245,1609]],"region":{"top_left_x":244,"top_left_y":1572,"width":309,"height":38},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"12da315ab7b34067b18c257f71d01050","type":"text","conversion_output":true,"parent_id":"e92a8e9873fa46618ff04f3c79ca84f5","text":"5.1.4 Medical care","text_display":"\n\n\\subsection*{5.1.4 Medical care}","confidence":1,"confidence_rate":1},{"cnt":[[245,1611],[1861,1611],[1861,1661],[245,1661]],"region":{"top_left_x":244,"top_left_y":1611,"width":1617,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4c8690850a0b4c8fb7250e1b6d637012","type":"text","conversion_output":true,"text":"Medical care is informed by the American College of Physicians guidelines on noninvasive treatment for","text_display":"\n\nMedical care is informed by the American College of Physicians guidelines on noninvasive treatment for","confidence":1,"confidence_rate":1},{"cnt":[[245,1659],[1807,1659],[1807,1704],[245,1704]],"region":{"top_left_x":244,"top_left_y":1658,"width":1563,"height":46},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a21e6403d9a54645bafc398692d7a79d","type":"text","conversion_output":true,"text":"\\(LBP ^{46}\\) and reflect what is delivered in primary care clinics. Medical care will be provided by licensed","text_display":" \\(LBP ^{46}\\) and reflect what is delivered in primary care clinics. Medical care will be provided by licensed","confidence":0.9951212396845222,"confidence_rate":0.999957839679139},{"cnt":[[245,1702],[1777,1702],[1777,1747],[245,1747]],"region":{"top_left_x":244,"top_left_y":1701,"width":1533,"height":46},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34aec25c729144cbafd3eab339638f39","type":"text","conversion_output":true,"text":"medical providers (e.g., MD, APN, PA) with a minimum of 3 years managing musculoskeletal pain","text_display":" medical providers (e.g., MD, APN, PA) with a minimum of 3 years managing musculoskeletal pain","confidence":1,"confidence_rate":1},{"cnt":[[245,1745],[1775,1745],[1775,1792],[245,1792]],"region":{"top_left_x":244,"top_left_y":1744,"width":1531,"height":48},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"180dec8adb8348f6bbb95f3607fd6ae3","type":"text","conversion_output":true,"text":"patients. Decisions regarding medical care (e.g., pharmacological management) and visit frequency","text_display":" patients. Decisions regarding medical care (e.g., pharmacological management) and visit frequency","confidence":1,"confidence_rate":1},{"cnt":[[245,1790],[1850,1790],[1850,1835],[245,1835]],"region":{"top_left_x":244,"top_left_y":1789,"width":1606,"height":46},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"08c420a6bf704343b85573688f358faf","type":"text","conversion_output":true,"text":"during the initial 8 -week intervention period will be made collaboratively by the provider and patient, as","text_display":" during the initial 8 -week intervention period will be made collaboratively by the provider and patient, as","confidence":0.8076171875,"confidence_rate":0.9981437500922651},{"cnt":[[245,1833],[1848,1833],[1848,1880],[245,1880]],"region":{"top_left_x":244,"top_left_y":1832,"width":1604,"height":48},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a1930e44b3c24acf82ba45f355ed044a","type":"text","conversion_output":true,"text":"normally occurs in clinical practice. Care will be provided via HIPAA compliant video conference (e.g.,","text_display":" normally occurs in clinical practice. Care will be provided via HIPAA compliant video conference (e.g.,","confidence":1,"confidence_rate":1},{"cnt":[[245,1878],[1811,1878],[1811,1923],[245,1923]],"region":{"top_left_x":244,"top_left_y":1877,"width":1568,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bc9a26f51df847c4ba7dc47e90a082c3","type":"text","conversion_output":true,"text":"Zoom), within outpatient clinics affiliated with UPITT and UMN, and/or over the phone: the Physical","text_display":" Zoom), within outpatient clinics affiliated with UPITT and UMN, and/or over the phone: the Physical","confidence":1,"confidence_rate":1},{"cnt":[[245,1921],[1755,1921],[1755,1966],[245,1966]],"region":{"top_left_x":244,"top_left_y":1920,"width":1512,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1af2065157384801afaee7d45f3686c3","type":"text","conversion_output":true,"text":"Therapy Clinical and Translational Research Center, Homewood Community Engagement Center","text_display":" Therapy Clinical and Translational Research Center, Homewood Community Engagement Center","confidence":1,"confidence_rate":1},{"cnt":[[245,2011],[245,1962],[1865,1964],[1865,2013]],"region":{"top_left_x":244,"top_left_y":1961,"width":1621,"height":53},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"225f42b476b84b03a48104249b514a47","type":"text","conversion_output":true,"text":"Wellness Pavilion and the Berman Center for Outcomes and Clinical Research, respectively. In case of a","text_display":" Wellness Pavilion and the Berman Center for Outcomes and Clinical Research, respectively. 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They will not be offered the option to receive treatment delivered in any of the other 3 study","text_display":" possible. 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Participants","confidence":1,"confidence_rate":1},{"cnt":[[245,2273],[1876,2273],[1876,2318],[245,2318]],"region":{"top_left_x":244,"top_left_y":2273,"width":1632,"height":46},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"909a3fc0279f4b608681dc076504d562","type":"text","conversion_output":true,"text":"can purchase over-the-counter (OTC) medications (e.g., Ibuprofen, \\(4 \\%\\) lidocaine patches); however, these","text_display":" can purchase over-the-counter (OTC) medications (e.g., Ibuprofen, \\(4 \\%\\) lidocaine patches); however, these","confidence":0.994631290435791,"confidence_rate":0.9999515041230366},{"cnt":[[245,2316],[1850,2316],[1850,2361],[245,2361]],"region":{"top_left_x":244,"top_left_y":2316,"width":1606,"height":46},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e7f6840a09a24b2486ead4a5b7e49d8c","type":"text","conversion_output":true,"text":"will be paid for by the study. Prescription medications (see Required and Allowed Interventions) will be","text_display":" will be paid for by the study. 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A treatment plan will be established, and the provider will","text_display":" medical history and exam as needed. 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Also, clinicians will assess the potential for risk factors","text_display":" regimens to avoid drug-drug adverse interactions. Also, clinicians will assess the potential for risk factors","confidence":1,"confidence_rate":1},{"cnt":[[245,1044],[1745,1044],[1745,1091],[245,1091]],"region":{"top_left_x":244,"top_left_y":1044,"width":1501,"height":48},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"82bed1ebc52d4c5c8a9e1db5bf9f45a0","type":"text","conversion_output":true,"text":"based on the patient's medical history prior to prescribing/recommending (prescription and OTC)","text_display":" based on the patient's medical history prior to prescribing/recommending (prescription and OTC)","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[1609,1087],[1609,1137],[245,1137]],"region":{"top_left_x":244,"top_left_y":1087,"width":1366,"height":50},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"92cee28d98fa46c2b6738f8dcfcca2e8","type":"text","conversion_output":true,"text":"medications and will suggest the lowest effective dose(s) for the shortest 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and attitudes to reduce balance out catastrophizing)","confidence":1,"confidence_rate":1},{"cnt":[[312,2378],[1515,2378],[1515,2421],[312,2421]],"region":{"top_left_x":311,"top_left_y":2378,"width":1204,"height":44},"line":48,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2498d7a69a0a4ddd8e571b22f3f11007","type":"text","conversion_output":true,"text":"- Problem- solving as needed (around pain impacts to maximize well being)","text_display":"\n- Problem- solving as needed (around pain impacts to maximize well being)","confidence":0.99951171875,"confidence_rate":0.9999937384747559},{"cnt":[[314,2423],[1553,2423],[1553,2466],[314,2466]],"region":{"top_left_x":313,"top_left_y":2423,"width":1241,"height":44},"line":49,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7f9c01b800e14110b400aac3839d4d56","type":"text","conversion_output":true,"text":"- Pleasant activity planning (helpful for those who have depressive 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plan activities to manage with pain)","text_display":"\n- Pacing (having an awareness of up/down time needed, plan activities to manage with pain)","confidence":1,"confidence_rate":1},{"cnt":[[309,299],[1384,299],[1384,342],[309,342]],"region":{"top_left_x":309,"top_left_y":298,"width":1075,"height":44},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8c06296cbb0d485c964049b12cdd489b","type":"text","conversion_output":true,"text":"- Symptom management exercises (flexion/extension, side-gliding)","text_display":"\n- Symptom management exercises (flexion/extension, side-gliding)","confidence":1,"confidence_rate":1},{"cnt":[[312,344],[1613,344],[1613,387],[312,387]],"region":{"top_left_x":311,"top_left_y":343,"width":1303,"height":44},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ff6a6822480545fe9b00f255a99e2bb1","type":"text","conversion_output":true,"text":"- Postural stabilization exercises (abdominal curl-ups, side 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'spine sparing' postures)","text_display":" with 'spine sparing' postures)","confidence":0.99951171875,"confidence_rate":0.9999860457974148},{"cnt":[[245,518],[642,518],[642,561],[245,561]],"region":{"top_left_x":244,"top_left_y":517,"width":399,"height":44},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fb7263cf67a04d02a9621cc7191895e3","type":"section_header","conversion_output":false,"children_ids":["615333cfe7554514ae365a76cdb659cc"],"text":"","text_display":""},{"cnt":[[249,520],[638,520],[638,556],[249,556]],"region":{"top_left_x":249,"top_left_y":519,"width":390,"height":38},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"615333cfe7554514ae365a76cdb659cc","type":"text","conversion_output":true,"parent_id":"fb7263cf67a04d02a9621cc7191895e3","text":"Prohibited Intervention","text_display":"\n\n\\section*{Prohibited 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goal of SSM training is to facilitate providers' confidence and ability to act as an effective coach for","text_display":"\n\nThe goal of SSM training is to facilitate providers' confidence and ability to act as an effective coach for","confidence":1,"confidence_rate":1},{"cnt":[[245,1182],[1867,1182],[1867,1227],[245,1227]],"region":{"top_left_x":244,"top_left_y":1181,"width":1623,"height":46},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a55d08ee2f3b438293f880dc8dc63689","type":"text","conversion_output":true,"text":"patients' in their self-management. Clinicians providing SSM will be required to complete online training","text_display":" patients' in their self-management. Clinicians providing SSM will be required to complete online training","confidence":1,"confidence_rate":1},{"cnt":[[247,1229],[1846,1229],[1846,1270],[247,1270]],"region":{"top_left_x":247,"top_left_y":1228,"width":1599,"height":42},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3eb65c45203747148bbd788f09cdbbcb","type":"text","conversion_output":true,"text":"materials covering information in the key SSM content areas. In addition, they will be required to attend","text_display":" materials covering information in the key SSM content areas. In addition, they will be required to attend","confidence":1,"confidence_rate":1},{"cnt":[[247,1272],[1863,1272],[1863,1315],[247,1315]],"region":{"top_left_x":247,"top_left_y":1271,"width":1616,"height":44},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ab81a7ae4b72486b8456c3465e3ffd04","type":"text","conversion_output":true,"text":"face-to-face training sessions (e.g., via Zoom) led by Drs. Greco, Evans, and other investigators. Face-to-","text_display":" face-to-face training sessions (e.g., via Zoom) led by Drs. Greco, Evans, and other investigators. Face-to","confidence":1,"confidence_rate":1},{"cnt":[[247,1315],[1708,1315],[1708,1360],[247,1360]],"region":{"top_left_x":247,"top_left_y":1314,"width":1462,"height":46},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"14c23a47f63a439bb6caf9010d788eec","type":"text","conversion_output":true,"text":"face training sessions will be highly interactive, and focus on the application of assessment and","text_display":"face training sessions will be highly interactive, and focus on the application of assessment and","confidence":1,"confidence_rate":1},{"cnt":[[247,1360],[1717,1360],[1717,1403],[247,1403]],"region":{"top_left_x":247,"top_left_y":1359,"width":1470,"height":44},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ec96ae3f730f4eacb57fc74d5b60cb64","type":"text","conversion_output":true,"text":"intervention elements of SSM, including delivering SSM in the remote environment. Prohibited","text_display":" intervention elements of SSM, including delivering SSM in the remote environment. Prohibited","confidence":1,"confidence_rate":1},{"cnt":[[247,1403],[1830,1403],[1830,1446],[247,1446]],"region":{"top_left_x":247,"top_left_y":1402,"width":1584,"height":44},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ed8641d6d51a411bb1ad220f747927e1","type":"text","conversion_output":true,"text":"interventions and other study specific related procedures (e.g., intervention documentation) will also be","text_display":" interventions and other study specific related procedures (e.g., intervention documentation) will also be","confidence":1,"confidence_rate":1},{"cnt":[[247,1448],[1846,1448],[1846,1491],[247,1491]],"region":{"top_left_x":247,"top_left_y":1448,"width":1599,"height":44},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d82184159de94ab497ef95fef184e5e8","type":"text","conversion_output":true,"text":"addressed. Monthly video and/or audio conferences will be held to build a community of practice and to","text_display":" addressed. Monthly video and/or audio conferences will be held to build a community of practice and to","confidence":0.7022936344146729,"confidence_rate":0.9967026102411475},{"cnt":[[245,1491],[1755,1491],[1755,1536],[245,1536]],"region":{"top_left_x":244,"top_left_y":1491,"width":1512,"height":46},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d036959935814bcf8ad353c59f7024b5","type":"text","conversion_output":true,"text":"problem-solve and facilitate a degree of consistency between providers and across sites. Refresher","text_display":" problem-solve and facilitate a degree of consistency between providers and across sites. 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Monthly video and/or audio","confidence":1,"confidence_rate":1},{"cnt":[[245,1491],[1798,1491],[1798,1540],[245,1540]],"region":{"top_left_x":244,"top_left_y":1491,"width":1555,"height":50},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d156af48e12d4c5393234ce5dd13fdd6","type":"text","conversion_output":true,"text":"conferences will be held to build a community of practice to problem-solve and facilitate a degree of","text_display":" conferences will be held to build a community of practice to problem-solve and facilitate a degree of","confidence":0.97412109375,"confidence_rate":0.9997526753366239},{"cnt":[[245,1538],[982,1538],[982,1583],[245,1583]],"region":{"top_left_x":244,"top_left_y":1538,"width":738,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"851547c38b1f4c458b219746e7599b0c","type":"text","conversion_output":true,"text":"consistency between providers and across sites.","text_display":" consistency between providers and across sites.","confidence":1,"confidence_rate":1},{"cnt":[[301,1661],[926,1661],[926,1714],[301,1714]],"region":{"top_left_x":300,"top_left_y":1660,"width":626,"height":55},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1a19781352d6457d9071ae6cad462b98","type":"section_header","conversion_output":false,"children_ids":["7911ece30974437b8dddf435ea20706e"],"text":"","text_display":""},{"cnt":[[305,1667],[922,1667],[922,1708],[305,1708]],"region":{"top_left_x":305,"top_left_y":1667,"width":617,"height":42},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7911ece30974437b8dddf435ea20706e","type":"text","conversion_output":true,"parent_id":"1a19781352d6457d9071ae6cad462b98","text":"5.3 Concomitant Interventions","text_display":"\n\n\\subsection*{5.3 Concomitant Interventions}","confidence":1,"confidence_rate":1},{"cnt":[[241,1732],[640,1732],[640,1785],[241,1785]],"region":{"top_left_x":240,"top_left_y":1731,"width":401,"height":55},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bbac893aa2bf46c2a12e8a997ebcab97","type":"section_header","conversion_output":false,"children_ids":["3c02f04720ae4563b5f84f80d5ddf36a"],"text":"","text_display":""},{"cnt":[[245,1736],[634,1736],[634,1781],[245,1781]],"region":{"top_left_x":244,"top_left_y":1735,"width":390,"height":47},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3c02f04720ae4563b5f84f80d5ddf36a","type":"text","conversion_output":true,"parent_id":"bbac893aa2bf46c2a12e8a997ebcab97","text":"Required Interventions","text_display":"\n\n\\section*{Required Interventions}","confidence":1,"confidence_rate":1},{"cnt":[[245,1779],[1884,1779],[1884,1824],[245,1824]],"region":{"top_left_x":244,"top_left_y":1778,"width":1641,"height":47},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e93a3f3f56c846d384505c95a5a28d6c","type":"text","conversion_output":true,"text":"All participants will receive basic standardized information regarding the generally favorable prognosis of","text_display":"\n\nAll participants will receive basic standardized information regarding the generally favorable prognosis of","confidence":1,"confidence_rate":1},{"cnt":[[245,1822],[1865,1822],[1865,1867],[245,1867]],"region":{"top_left_x":244,"top_left_y":1821,"width":1621,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5cd40a8370f3474e8583d912c07fbcfe","type":"text","conversion_output":true,"text":"acute and sub-acute LBP. We will provide patients with an updated version of the Back in Action book \\({ }^{11}\\)","text_display":" acute and sub-acute LBP. We will provide patients with an updated version of the Back in Action book \\({ }^{11}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1865],[1207,1865],[1207,1914],[245,1914]],"region":{"top_left_x":244,"top_left_y":1864,"width":964,"height":51},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7ced9d2b61e5482eb586cfede5805c04","type":"text","conversion_output":true,"text":"\\({ }^{44}\\) in print and/or electronic formats. The Back in Action book:","text_display":"\n\\({ }^{44}\\) in print and/or electronic formats. The Back in Action book:","confidence":1,"confidence_rate":1},{"cnt":[[309,1910],[1790,1910],[1790,1957],[309,1957]],"region":{"top_left_x":309,"top_left_y":1909,"width":1481,"height":49},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"31e51fad0f0c4659bf5387d0fc8c2d63","type":"text","conversion_output":true,"text":"- Encourages patients to engage in their normal activities as soon as possible, even if it causes","text_display":"\n- Encourages patients to engage in their normal activities as soon as possible, even if it causes","confidence":1,"confidence_rate":1},{"cnt":[[370,1955],[544,1955],[544,2000],[370,2000]],"region":{"top_left_x":369,"top_left_y":1955,"width":175,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"be93860068d24d21a4dc97fc4e09d807","type":"text","conversion_output":true,"text":"some pain.","text_display":" some pain.","confidence":1,"confidence_rate":1},{"cnt":[[309,1998],[1485,1998],[1485,2047],[309,2047]],"region":{"top_left_x":309,"top_left_y":1998,"width":1176,"height":50},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1b67eef4752c45128548232d9798c914","type":"text","conversion_output":true,"text":"- Encourages general aerobic exercise like walking, swimming, bicycling.","text_display":"\n- Encourages general aerobic exercise like walking, swimming, bicycling.","confidence":1,"confidence_rate":1},{"cnt":[[309,2045],[1858,2045],[1858,2090],[309,2090]],"region":{"top_left_x":309,"top_left_y":2045,"width":1550,"height":46},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"76110827b0484b8b9db7d67a118d3614","type":"text","conversion_output":true,"text":"- Provides a very brief summary of the general causes of LBP, reassurance that it is rarely due to a","text_display":"\n- Provides a very brief summary of the general causes of LBP, reassurance that it is rarely due to a","confidence":1,"confidence_rate":1},{"cnt":[[370,2088],[1721,2088],[1721,2136],[370,2136]],"region":{"top_left_x":369,"top_left_y":2088,"width":1352,"height":48},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c20cc673fc01474388258820e66f9e1c","type":"text","conversion_output":true,"text":"serious problem, and that the majority of cases do not require specialty care or imaging.","text_display":" serious problem, and that the majority of cases do not require specialty care or imaging.","confidence":1,"confidence_rate":1},{"cnt":[[309,2131],[1760,2131],[1760,2179],[309,2179]],"region":{"top_left_x":309,"top_left_y":2131,"width":1451,"height":48},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cb1638753da8404a9dd22d704da59885","type":"text","conversion_output":true,"text":"- Emphasizes the patient's role in facilitating their own recovery by providing some general","text_display":"\n- Emphasizes the patient's role in facilitating their own recovery by providing some general","confidence":1,"confidence_rate":1},{"cnt":[[370,2176],[1818,2176],[1818,2224],[370,2224]],"region":{"top_left_x":369,"top_left_y":2176,"width":1449,"height":48},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ed6e9a0f67394795ac680e592a6f731a","type":"text","conversion_output":true,"text":"recommendations for symptom management (e.g., use of heat, changing positions frequently).","text_display":" recommendations for symptom management (e.g., use of heat, changing positions frequently).","confidence":1,"confidence_rate":1},{"cnt":[[241,2260],[621,2260],[621,2310],[241,2310]],"region":{"top_left_x":240,"top_left_y":2260,"width":381,"height":50},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8dcee65b8a5142f582db0ab67647738c","type":"section_header","conversion_output":false,"children_ids":["e56c7572c2654863885c45e1924240b9"],"text":"","text_display":""},{"cnt":[[245,2264],[617,2264],[617,2305],[245,2305]],"region":{"top_left_x":244,"top_left_y":2264,"width":373,"height":42},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e56c7572c2654863885c45e1924240b9","type":"text","conversion_output":true,"parent_id":"8dcee65b8a5142f582db0ab67647738c","text":"Allowed Interventions","text_display":"\n\n\\section*{Allowed Interventions}","confidence":1,"confidence_rate":1},{"cnt":[[245,2307],[1880,2307],[1880,2357],[245,2357]],"region":{"top_left_x":244,"top_left_y":2307,"width":1636,"height":50},"line":47,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"417a1639602c474a95d375f4e801563c","type":"text","conversion_output":true,"text":"Participants will be allowed to use OTC medications as needed during the course of the study. In addition,","text_display":"\n\nParticipants will be allowed to use OTC medications as needed during the course of the study. In addition,","confidence":1,"confidence_rate":1},{"cnt":[[245,2350],[1863,2350],[1863,2400],[245,2400]],"region":{"top_left_x":244,"top_left_y":2350,"width":1619,"height":50},"line":48,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9346a52aec0a4703b3d5f356b561923a","type":"text","conversion_output":true,"text":"participants will be allowed to continue self-care practices (e.g., heat, stretching) for LBP they used prior","text_display":" participants will be allowed to continue self-care practices (e.g., heat, stretching) for LBP they used prior","confidence":1,"confidence_rate":1},{"cnt":[[245,2398],[1846,2398],[1846,2443],[245,2443]],"region":{"top_left_x":244,"top_left_y":2397,"width":1602,"height":46},"line":49,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"eea2d57d3926451abf2728543c65ca37","type":"text","conversion_output":true,"text":"to the study. Participants not assigned to MC who experience a significant worsening of LBP symptoms","text_display":" to the study. Participants not assigned to MC who experience a significant worsening of LBP symptoms","confidence":0.99951171875,"confidence_rate":0.9999953485775026},{"cnt":[[245,2441],[1794,2441],[1794,2488],[245,2488]],"region":{"top_left_x":244,"top_left_y":2440,"width":1550,"height":48},"line":50,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3cf8d2b52f59438388106816d816844e","type":"text","conversion_output":true,"text":"that cannot be managed by the assigned and concomitant interventions will be referred to the study's","text_display":" that cannot be managed by the assigned and concomitant interventions will be referred to the study's","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":51,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"e023d872ddbe417ab0b3ff31ed0df888","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 37","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-38","page":38,"lines":[{"cnt":[[245,251],[1697,251],[1697,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1454,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2b56974749b144be993c13cbaf5a3920","type":"text","conversion_output":true,"text":"medical care provider for a short-course of 'rescue medications', using a protocol successfully","text_display":"\nmedical care provider for a short-course of 'rescue medications', using a protocol successfully","confidence":1,"confidence_rate":1},{"cnt":[[245,294],[1689,294],[1689,346],[245,346]],"region":{"top_left_x":244,"top_left_y":294,"width":1445,"height":52},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3437126523e34c45be9d753cdc9b1f8d","type":"text","conversion_output":true,"text":"implemented, but rarely required, in previous studies by the investigators. \\({ }^{10}\\) 11 See section 5.5.","text_display":" implemented, but rarely required, in previous studies by the investigators. \\({ }^{10}\\) 11 See section 5.5.","confidence":0.43740123859606683,"confidence_rate":0.9927089719370845},{"cnt":[[245,382],[1809,382],[1809,432],[245,432]],"region":{"top_left_x":244,"top_left_y":382,"width":1565,"height":50},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"507833ddff3e458c807f83d41732c602","type":"text","conversion_output":true,"text":"Treating clinicians, in consultation with the PIs, may refer in the case of AEs or if LBP complications","text_display":"\n\nTreating clinicians, in consultation with the PIs, may refer in the case of AEs or if LBP complications","confidence":1,"confidence_rate":1},{"cnt":[[245,425],[1794,425],[1794,475],[245,475]],"region":{"top_left_x":244,"top_left_y":425,"width":1550,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"97f96a0d4c8c444498507c18aebd1498","type":"text","conversion_output":true,"text":"develop that cannot be adequately managed with the assigned intervention (e.g., disc herniation with","text_display":" develop that cannot be adequately managed with the assigned intervention (e.g., disc herniation with","confidence":1,"confidence_rate":1},{"cnt":[[245,471],[1725,471],[1725,522],[245,522]],"region":{"top_left_x":244,"top_left_y":470,"width":1482,"height":53},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e7d7510dc8a748668880e0c8994359e5","type":"text","conversion_output":true,"text":"progressive neurological deficits). Participants will be informed to seek any required care for all","text_display":" progressive neurological deficits). Participants will be informed to seek any required care for all","confidence":1,"confidence_rate":1},{"cnt":[[245,516],[763,516],[763,563],[245,563]],"region":{"top_left_x":244,"top_left_y":515,"width":519,"height":48},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2b6662b2d1734158820e8c84308fee5b","type":"text","conversion_output":true,"text":"conditions unrelated to the study.","text_display":" conditions unrelated to the study.","confidence":1,"confidence_rate":1},{"cnt":[[236,597],[664,597],[664,651],[236,651]],"region":{"top_left_x":236,"top_left_y":597,"width":428,"height":54},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8bba225c836d4b66bcc16bcd00d3bef1","type":"section_header","conversion_output":false,"children_ids":["c13d7670f1a4474d8e73497ae6dc0420"],"text":"","text_display":""},{"cnt":[[245,602],[660,602],[660,647],[245,647]],"region":{"top_left_x":244,"top_left_y":601,"width":416,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c13d7670f1a4474d8e73497ae6dc0420","type":"text","conversion_output":true,"parent_id":"8bba225c836d4b66bcc16bcd00d3bef1","text":"Prohibited Interventions","text_display":"\n\n\\section*{Prohibited Interventions}","confidence":1,"confidence_rate":1},{"cnt":[[245,645],[1828,645],[1828,694],[245,694]],"region":{"top_left_x":244,"top_left_y":644,"width":1585,"height":50},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a223e7d42f5a417283d93a109e0ef157","type":"text","conversion_output":true,"text":"Participants will be asked to limit treatment to their assigned intervention for the length of the initial 8-","text_display":"\n\nParticipants will be asked to limit treatment to their assigned intervention for the length of the initial 8","confidence":1,"confidence_rate":1},{"cnt":[[245,692],[1841,692],[1841,741],[245,741]],"region":{"top_left_x":244,"top_left_y":691,"width":1598,"height":51},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"caaa3531a19c4e47ab00ea3a3f14df00","type":"text","conversion_output":true,"text":"week intervention period; similarly providers will be taught to refrain from delivering interventions that","text_display":"week intervention period; similarly providers will be taught to refrain from delivering interventions that","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1738,735],[1738,784],[245,784]],"region":{"top_left_x":244,"top_left_y":734,"width":1495,"height":51},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d8c0919e955a48368422ffe850b58253","type":"text","conversion_output":true,"text":"fall outside the scope of the study protocols (see above). However, participants retain the right to","text_display":" fall outside the scope of the study protocols (see above). However, participants retain the right to","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[692,778],[692,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":448,"height":51},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"123215f80bd147ba8c32daa53e76b420","type":"text","conversion_output":true,"text":"discontinue care at any time.","text_display":" discontinue care at any time.","confidence":1,"confidence_rate":1},{"cnt":[[299,859],[857,859],[857,917],[299,917]],"region":{"top_left_x":298,"top_left_y":859,"width":560,"height":59},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e5b2489523cc4ad2b72f915070ec0ea4","type":"section_header","conversion_output":false,"children_ids":["9ccdd6249532420e8b003dbf5659eccd"],"text":"","text_display":""},{"cnt":[[305,866],[849,866],[849,913],[305,913]],"region":{"top_left_x":305,"top_left_y":865,"width":544,"height":49},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9ccdd6249532420e8b003dbf5659eccd","type":"text","conversion_output":true,"parent_id":"e5b2489523cc4ad2b72f915070ec0ea4","text":"5.4 Adherence Assessment","text_display":"\n\n\\subsection*{5.4 Adherence Assessment}","confidence":1,"confidence_rate":1},{"cnt":[[245,932],[1732,932],[1732,982],[245,982]],"region":{"top_left_x":244,"top_left_y":932,"width":1488,"height":50},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"88ca13d5c5124a188239ec75e4b4bf32","type":"text","conversion_output":true,"text":"The total number of treatments will be decided by the treating clinician based on each individual","text_display":"\n\nThe total number of treatments will be decided by the treating clinician based on each individual","confidence":1,"confidence_rate":1},{"cnt":[[245,975],[1841,975],[1841,1025],[245,1025]],"region":{"top_left_x":244,"top_left_y":975,"width":1598,"height":50},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1dc50f91cfa243fc8c5983671b114896","type":"text","conversion_output":true,"text":"participant's clinical presentation and response to care, as is done in clinical practice. We anticipate 4-6","text_display":" participant's clinical presentation and response to care, as is done in clinical practice. We anticipate 4-6","confidence":0.99951171875,"confidence_rate":0.9999956778810385},{"cnt":[[245,1023],[1807,1023],[1807,1068],[245,1068]],"region":{"top_left_x":244,"top_left_y":1022,"width":1563,"height":46},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ea3544677b93455d9917d801dbb69892","type":"text","conversion_output":true,"text":"visits being prescribed for most participants receiving SMT, 4-8 visits for most participants receiving","text_display":" visits being prescribed for most participants receiving SMT, 4-8 visits for most participants receiving","confidence":0.99951171875,"confidence_rate":0.9999954777833909},{"cnt":[[245,1066],[1772,1066],[1772,1113],[245,1113]],"region":{"top_left_x":244,"top_left_y":1065,"width":1529,"height":48},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"acfb4aae27c1424d9af20d40165f0cd5","type":"text","conversion_output":true,"text":"SSM, and 2-4 visits for most participants receiving medical care. Participant adherence to assigned","text_display":" SSM, and 2-4 visits for most participants receiving medical care. Participant adherence to assigned","confidence":0.99853515625,"confidence_rate":0.9999859047370074},{"cnt":[[245,1109],[1274,1109],[1274,1154],[245,1154]],"region":{"top_left_x":244,"top_left_y":1108,"width":1031,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4f6534edd8a0420f97fe722212d8cd8b","type":"text","conversion_output":true,"text":"interventions will be documented at each visit in the clinical notes.","text_display":" interventions will be documented at each visit in the clinical notes.","confidence":1,"confidence_rate":1},{"cnt":[[245,1195],[1792,1195],[1792,1244],[245,1244]],"region":{"top_left_x":244,"top_left_y":1194,"width":1548,"height":50},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b8de4b20c22a4f91921c0d64627ee87e","type":"text","conversion_output":true,"text":"Treatment adherence has been defined in the Threshold Criteria for Transition as attending \\(\\geq 75 \\%\\) of","text_display":"\n\nTreatment adherence has been defined in the Threshold Criteria for Transition as attending \\(\\geq 75 \\%\\) of","confidence":1,"confidence_rate":1},{"cnt":[[245,1242],[1841,1242],[1841,1291],[245,1291]],"region":{"top_left_x":244,"top_left_y":1241,"width":1598,"height":51},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"62150759c7204a83b22f0b44c7306039","type":"text","conversion_output":true,"text":"prescribed intervention visits. We have expanded on this definition by including a minimum number of","text_display":" prescribed intervention visits. We have expanded on this definition by including a minimum number of","confidence":1,"confidence_rate":1},{"cnt":[[245,1285],[1738,1285],[1738,1334],[245,1334]],"region":{"top_left_x":244,"top_left_y":1284,"width":1495,"height":51},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34943e4abd424e1580d982c3836db370","type":"text","conversion_output":true,"text":"visits for each intervention and requiring participants not drop out of active care to be considered","text_display":" visits for each intervention and requiring participants not drop out of active care to be considered","confidence":1,"confidence_rate":1},{"cnt":[[245,1328],[1854,1328],[1854,1377],[245,1377]],"region":{"top_left_x":244,"top_left_y":1327,"width":1611,"height":51},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"689e068ccc6b4449846e90d1ab5c4861","type":"text","conversion_output":true,"text":"adherent. A minimum of 2 sessions will be required for participants in SMT and MC, and minimum of 4","text_display":" adherent. 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In addition, fidelity will be assessed by video/audio recordings or in person","text_display":" and prohibited interventions. In addition, fidelity will be assessed by video/audio recordings or in person","confidence":1,"confidence_rate":1},{"cnt":[[245,1547],[1871,1547],[1871,1596],[245,1596]],"region":{"top_left_x":244,"top_left_y":1546,"width":1628,"height":51},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e3270ac20f2749b393022f0eb3aff7b1","type":"text","conversion_output":true,"text":"observations of randomly determined intervention visits. Fidelity assessments will occur monthly, for six","text_display":" observations of randomly determined intervention visits. Fidelity assessments will occur monthly, for six","confidence":1,"confidence_rate":1},{"cnt":[[245,1590],[1815,1590],[1815,1641],[245,1641]],"region":{"top_left_x":244,"top_left_y":1589,"width":1572,"height":53},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e659f7009af24e4598e3b1e7c3fa4b95","type":"text","conversion_output":true,"text":"months, on each provider currently treating patients, then quarterly thereafter. If concerns arise during","text_display":" months, on each provider currently treating patients, then quarterly thereafter. If concerns arise during","confidence":1,"confidence_rate":1},{"cnt":[[245,1637],[1790,1637],[1790,1689],[245,1689]],"region":{"top_left_x":244,"top_left_y":1637,"width":1546,"height":52},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e5126c7cf6944f538f1ed59f2b1da7ca","type":"text","conversion_output":true,"text":"quarterly reviews, the provider may resort back to monthly fidelity checks as needed. The DCC will","text_display":" quarterly reviews, the provider may resort back to monthly fidelity checks as needed. The DCC will","confidence":1,"confidence_rate":1},{"cnt":[[245,1684],[1721,1684],[1721,1732],[245,1732]],"region":{"top_left_x":244,"top_left_y":1684,"width":1477,"height":48},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d300be105abb475bac20bffae3b45dcd","type":"text","conversion_output":true,"text":"monitor the treatment administered forms for activities defined as 'out of scope' for the defined","text_display":" monitor the treatment administered forms for activities defined as 'out of scope' for the defined","confidence":1,"confidence_rate":1},{"cnt":[[245,1727],[1867,1727],[1867,1777],[245,1777]],"region":{"top_left_x":244,"top_left_y":1727,"width":1623,"height":50},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"053d4ecaa12c439f93da9cb16c8e1de7","type":"text","conversion_output":true,"text":"intervention (e.g., spinal manipulation delivered to a participant assigned to structured self-management).","text_display":" intervention (e.g., spinal manipulation delivered to a participant assigned to structured self-management).","confidence":0.99951171875,"confidence_rate":0.9999956392907748},{"cnt":[[245,1770],[1841,1770],[1841,1820],[245,1820]],"region":{"top_left_x":244,"top_left_y":1770,"width":1598,"height":50},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1dd9153587c54e2fb02b73689cd72856","type":"text","conversion_output":true,"text":"Out of scope activities indicating potential crossover will be flagged through automated real-time alerts","text_display":" Out of scope activities indicating potential crossover will be flagged through automated real-time alerts","confidence":1,"confidence_rate":1},{"cnt":[[245,1815],[1846,1815],[1846,1863],[245,1863]],"region":{"top_left_x":244,"top_left_y":1815,"width":1602,"height":48},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"88949a422c0243b9941962041dbe1eba","type":"text","conversion_output":true,"text":"created by the DCC which will immediately be sent to the relevant site's PI and study coordinators. The","text_display":" created by the DCC which will immediately be sent to the relevant site's PI and study coordinators. The","confidence":1,"confidence_rate":1},{"cnt":[[245,1861],[1841,1861],[1841,1910],[245,1910]],"region":{"top_left_x":244,"top_left_y":1860,"width":1598,"height":50},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"823508b854bb4695a26ee2f2fc96d7bb","type":"text","conversion_output":true,"text":"site study coordinators are best suited for contacting providers, as they will be familiar to them and will","text_display":" site study coordinators are best suited for contacting providers, as they will be familiar to them and will","confidence":1,"confidence_rate":1},{"cnt":[[245,1904],[1762,1904],[1762,1953],[245,1953]],"region":{"top_left_x":244,"top_left_y":1903,"width":1518,"height":50},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1bd26b493a8d4ee7bb5372c29f556460","type":"text","conversion_output":true,"text":"have developed collaborative working relationships that ensure successful project implementation.","text_display":" have developed collaborative working relationships that ensure successful project implementation.","confidence":1,"confidence_rate":1},{"cnt":[[245,1946],[1729,1946],[1729,1996],[245,1996]],"region":{"top_left_x":244,"top_left_y":1946,"width":1486,"height":50},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ec9172de4e364a3482ce610d6191d2bc","type":"text","conversion_output":true,"text":"Additional actions would include remedial training for the providers and potential removal from","text_display":" Additional actions would include remedial training for the providers and potential removal from","confidence":1,"confidence_rate":1},{"cnt":[[245,1989],[578,1989],[578,2041],[245,2041]],"region":{"top_left_x":244,"top_left_y":1989,"width":334,"height":53},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c8e663d354cf41ab84b2b64840723a9c","type":"text","conversion_output":true,"text":"providing study care.","text_display":" providing study care.","confidence":1,"confidence_rate":1},{"cnt":[[236,2118],[629,2118],[629,2172],[236,2172]],"region":{"top_left_x":236,"top_left_y":2118,"width":394,"height":55},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b923508968e6459bbf8ba5d46eeed931","type":"section_header","conversion_output":false,"children_ids":["43aa6d63a1274f199036f566bc39a4b6"],"text":"","text_display":""},{"cnt":[[245,2123],[621,2123],[621,2168],[245,2168]],"region":{"top_left_x":244,"top_left_y":2122,"width":377,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"43aa6d63a1274f199036f566bc39a4b6","type":"text","conversion_output":true,"parent_id":"b923508968e6459bbf8ba5d46eeed931","text":"5.5 Rescue Medication","text_display":"\n\n\\subsection*{5.5 Rescue Medication}","confidence":1,"confidence_rate":1},{"cnt":[[245,2166],[1871,2166],[1871,2215],[245,2215]],"region":{"top_left_x":244,"top_left_y":2165,"width":1628,"height":51},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c1351e00917f4ac1bb72d69398c74434","type":"text","conversion_output":true,"text":"Participants not assigned to MC who experience a significant worsening of LBP symptoms that cannot be","text_display":"\n\nParticipants not assigned to MC who experience a significant worsening of LBP symptoms that cannot be","confidence":1,"confidence_rate":1},{"cnt":[[245,2211],[1861,2211],[1861,2258],[245,2258]],"region":{"top_left_x":244,"top_left_y":2210,"width":1617,"height":49},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"644530b9c16d4001b669f2eb75c5b9bd","type":"text","conversion_output":true,"text":"managed by the assigned and concomitant interventions will be referred to a study medical care provider","text_display":" managed by the assigned and concomitant interventions will be referred to a study medical care provider","confidence":1,"confidence_rate":1},{"cnt":[[245,2256],[1863,2256],[1863,2301],[245,2301]],"region":{"top_left_x":244,"top_left_y":2255,"width":1619,"height":46},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9de28e013ab741f3851d87a76dd098be","type":"text","conversion_output":true,"text":"for a short-course of rescue medications. Skeletal muscle relaxants and non-steroidal anti-inflammatories","text_display":" for a short-course of rescue medications. Skeletal muscle relaxants and non-steroidal anti-inflammatories","confidence":1,"confidence_rate":1},{"cnt":[[245,2299],[1841,2299],[1841,2346],[245,2346]],"region":{"top_left_x":244,"top_left_y":2298,"width":1598,"height":49},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6c03dd37083842e3b7975899a483ab9d","type":"text","conversion_output":true,"text":"are the first line rescue medications that will be offered based on the participant's individual medication","text_display":" are the first line rescue medications that will be offered based on the participant's individual medication","confidence":1,"confidence_rate":1},{"cnt":[[245,2342],[1865,2342],[1865,2391],[245,2391]],"region":{"top_left_x":244,"top_left_y":2341,"width":1621,"height":51},"line":44,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f237d4880a1844b8b53ad02a63df1d3a","type":"text","conversion_output":true,"text":"risk profile. Additional medication may be used when first line rescue medications are contraindicated or","text_display":" risk profile. Additional medication may be used when first line rescue medications are contraindicated or","confidence":1,"confidence_rate":1},{"cnt":[[245,2385],[1663,2385],[1663,2434],[245,2434]],"region":{"top_left_x":244,"top_left_y":2384,"width":1419,"height":51},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9a6ad2ae63794323acc475ce138a297f","type":"text","conversion_output":true,"text":"do not sufficiently manage the participant's pain (e.g., opioids, benzodiazepines, antiseizure","text_display":" do not sufficiently manage the participant's pain (e.g., opioids, benzodiazepines, antiseizure","confidence":1,"confidence_rate":1},{"cnt":[[245,2428],[1863,2428],[1863,2479],[245,2479]],"region":{"top_left_x":244,"top_left_y":2427,"width":1619,"height":53},"line":46,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9fef2758430b462bb61f56c2a3e6b87c","type":"text","conversion_output":true,"text":"medications). \\({ }^{46}\\) Use of rescue medication will be monitored and differences across intervention arms will","text_display":" medications). \\({ }^{46}\\) Use of rescue medication will be monitored and differences across intervention arms will","confidence":1,"confidence_rate":1},{"cnt":[[1504,2580],[1882,2580],[1882,2632],[1504,2632]],"region":{"top_left_x":1503,"top_left_y":2580,"width":380,"height":52},"line":47,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"6f50ad746d0b40a4acfe95662e52966a","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 38","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-39","page":39,"lines":[{"cnt":[[245,251],[1766,251],[1766,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1523,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ec97e1b6b0464d09ba3dfe596b6f618e","type":"text","conversion_output":true,"text":"be compared. Further, medical providers should make reference to the Back in Action booklet and","text_display":"\nbe compared. 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The addendum consent will be given to the participant at a study visit or mailed","confidence":0.99951171875,"confidence_rate":0.9999956778810385},{"cnt":[[245,907],[638,907],[638,956],[245,956]],"region":{"top_left_x":244,"top_left_y":906,"width":395,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"68577acc278040f5a6acf931f3cd391a","type":"text","conversion_output":true,"text":"to the participant's home.","text_display":" to the participant's home.","confidence":1,"confidence_rate":1},{"cnt":[[236,1003],[423,1003],[423,1063],[236,1063]],"region":{"top_left_x":236,"top_left_y":1003,"width":188,"height":61},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d96996680b184a56a788fe01a8dac995","type":"section_header","conversion_output":false,"children_ids":["fa09e8b8528540bd9e5ddc74d0d2c558"],"text":"","text_display":""},{"cnt":[[245,1010],[419,1010],[419,1057],[245,1057]],"region":{"top_left_x":244,"top_left_y":1009,"width":175,"height":49},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fa09e8b8528540bd9e5ddc74d0d2c558","type":"text","conversion_output":true,"parent_id":"d96996680b184a56a788fe01a8dac995","text":"Screening","text_display":"\n\n\\section*{Screening}","confidence":1,"confidence_rate":1},{"cnt":[[245,1059],[1794,1059],[1794,1111],[245,1111]],"region":{"top_left_x":244,"top_left_y":1059,"width":1550,"height":52},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a7979ab77ad64b71a4b7981a26eec460","type":"text","conversion_output":true,"text":"Screening will occur at 2 time points: an initial screen (online and phone) and a face to face (e.g., in-","text_display":"\n\nScreening will occur at 2 time points: an initial screen (online and phone) and a face to face (e.g., in","confidence":0.99951171875,"confidence_rate":0.9999956778810385},{"cnt":[[245,1109],[1173,1109],[1173,1160],[245,1160]],"region":{"top_left_x":244,"top_left_y":1108,"width":930,"height":53},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"159f43bb54f844998f3c91156920929c","type":"text","conversion_output":true,"text":"person or videoconference) baseline screening appointment.","text_display":"person or videoconference) baseline screening appointment.","confidence":1,"confidence_rate":1},{"cnt":[[241,1203],[758,1203],[758,1265],[241,1265]],"region":{"top_left_x":240,"top_left_y":1203,"width":519,"height":63},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"193a70d348424f58a7943588fd7b8674","type":"section_header","conversion_output":false,"children_ids":["666b2474d1174d04b80d354bec726887"],"text":"","text_display":""},{"cnt":[[245,1212],[754,1212],[754,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":511,"height":51},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"666b2474d1174d04b80d354bec726887","type":"text","conversion_output":true,"parent_id":"193a70d348424f58a7943588fd7b8674","text":"Initial Screening (Online/Phone)","text_display":"\n\n\\section*{Initial Screening (Online/Phone)}","confidence":0.99853515625,"confidence_rate":0.9999603813880137},{"cnt":[[309,1263],[1850,1263],[1850,1311],[309,1311]],"region":{"top_left_x":309,"top_left_y":1263,"width":1541,"height":48},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"845dd38f2e4a4b7ba9c93b8df9d68963","type":"text","conversion_output":true,"text":"- Following consent, potential participants will be asked a series of self-report questions to screen","text_display":"\n- Following consent, potential participants will be asked a series of self-report questions to screen","confidence":1,"confidence_rate":1},{"cnt":[[370,1311],[1798,1311],[1798,1360],[370,1360]],"region":{"top_left_x":369,"top_left_y":1310,"width":1430,"height":50},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7d50ac1824ee41e3b95ccab8f7f0b6da","type":"text","conversion_output":true,"text":"basic eligibility. Persons who meet basic inclusion criteria (e.g., age, medium or high risk on","text_display":" basic eligibility. Persons who meet basic inclusion criteria (e.g., age, medium or high risk on","confidence":1,"confidence_rate":1},{"cnt":[[370,1362],[1830,1362],[1830,1412],[370,1412]],"region":{"top_left_x":369,"top_left_y":1362,"width":1462,"height":50},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"46decf9943e14558800df9937323919d","type":"text","conversion_output":true,"text":"STarT Back Screening Tool, LBP intensity of 3 or higher, English literacy) and who otherwise","text_display":" STarT Back Screening Tool, LBP intensity of 3 or higher, English literacy) and who otherwise","confidence":1,"confidence_rate":1},{"cnt":[[370,1414],[1835,1414],[1835,1463],[370,1463]],"region":{"top_left_x":369,"top_left_y":1413,"width":1466,"height":51},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2a625b156f124b91b6d98460c3e33d0e","type":"text","conversion_output":true,"text":"have no obvious exclusions (e.g., pregnancy, history of surgical fusion of lumbar spine) will be","text_display":" have no obvious exclusions (e.g., pregnancy, history of surgical fusion of lumbar spine) will be","confidence":0.99951171875,"confidence_rate":0.9999951643631956},{"cnt":[[370,1463],[1824,1463],[1824,1515],[370,1515]],"region":{"top_left_x":369,"top_left_y":1463,"width":1456,"height":52},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0a4726a631044cbb99de22fda3f250c0","type":"text","conversion_output":true,"text":"contacted by study staff, who will ask specific health-related, questions pertaining to inclusion","text_display":" contacted by study staff, who will ask specific health-related, questions pertaining to inclusion","confidence":1,"confidence_rate":1},{"cnt":[[370,1515],[823,1515],[823,1566],[370,1566]],"region":{"top_left_x":369,"top_left_y":1514,"width":454,"height":53},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7b09731b4ecc414aab8d1e357e31234d","type":"text","conversion_output":true,"text":"(e.g., LBP episode duration).","text_display":" (e.g., LBP episode duration).","confidence":1,"confidence_rate":1},{"cnt":[[309,1598],[1815,1598],[1815,1648],[309,1648]],"region":{"top_left_x":309,"top_left_y":1598,"width":1507,"height":50},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"093c2ff4db384014963e31b184fad617","type":"text","conversion_output":true,"text":"- In-person or videoconference screening appointments will occur as soon as possible, but must","text_display":"\n- In-person or videoconference screening appointments will occur as soon as possible, but must","confidence":1,"confidence_rate":1},{"cnt":[[370,1650],[1846,1650],[1846,1699],[370,1699]],"region":{"top_left_x":369,"top_left_y":1650,"width":1477,"height":50},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"60f871fb3ab945ee974ae9373df6a241","type":"text","conversion_output":true,"text":"occur within 30 days of completing the phone screen; otherwise, the initial phone screen will be","text_display":" occur within 30 days of completing the phone screen; otherwise, the initial phone screen will be","confidence":1,"confidence_rate":1},{"cnt":[[370,1702],[492,1702],[492,1742],[370,1742]],"region":{"top_left_x":369,"top_left_y":1701,"width":123,"height":42},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"764bf10dab35495cbbfc04bd7f8d663b","type":"text","conversion_output":true,"text":"redone.","text_display":" redone.","confidence":1,"confidence_rate":1},{"cnt":[[236,1777],[1008,1777],[1008,1841],[236,1841]],"region":{"top_left_x":236,"top_left_y":1776,"width":772,"height":66},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ce119b13ab45447eb1831c0a3a0c2ea3","type":"section_header","conversion_output":false,"children_ids":["5db287dec86648cdb2cbb112200f43e2"],"text":"","text_display":""},{"cnt":[[245,1783],[999,1783],[999,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1783,"width":756,"height":54},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5db287dec86648cdb2cbb112200f43e2","type":"text","conversion_output":true,"parent_id":"ce119b13ab45447eb1831c0a3a0c2ea3","text":"Baseline Screening (In Person/Videoconference)","text_display":"\n\n\\section*{Baseline Screening (In Person/Videoconference)}","confidence":0.99853515625,"confidence_rate":0.9999712569291195},{"cnt":[[309,1835],[1721,1835],[1721,1886],[309,1886]],"region":{"top_left_x":309,"top_left_y":1834,"width":1412,"height":53},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6e99ed731ff244d3a4e5887665d8930f","type":"text","conversion_output":true,"text":"- Written or e-informed consent will be collected from participants prior to any screening","text_display":"\n- Written or e-informed consent will be collected from participants prior to any screening","confidence":1,"confidence_rate":1},{"cnt":[[370,1886],[733,1886],[733,1936],[370,1936]],"region":{"top_left_x":369,"top_left_y":1886,"width":364,"height":50},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d0633c17b0174e559e6d9102f0fa7a8c","type":"text","conversion_output":true,"text":"procedures at this visit.","text_display":" procedures at this visit.","confidence":1,"confidence_rate":1},{"cnt":[[309,1972],[1738,1972],[1738,2022],[309,2022]],"region":{"top_left_x":309,"top_left_y":1972,"width":1430,"height":50},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0733dea439ab4721866fb139967a5b22","type":"text","conversion_output":true,"text":"- Participants will complete self-report questionnaires to determine eligibility that include:","text_display":"\n- Participants will complete self-report questionnaires to determine eligibility that include:","confidence":1,"confidence_rate":1},{"cnt":[[434,2058],[728,2058],[728,2108],[434,2108]],"region":{"top_left_x":433,"top_left_y":2058,"width":296,"height":50},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"03c088dcaa09412d8abec90e19f73080","type":"text","conversion_output":true,"text":"- Demographics","text_display":"\n- Demographics","confidence":1,"confidence_rate":1},{"cnt":[[434,2144],[1124,2144],[1124,2194],[434,2194]],"region":{"top_left_x":433,"top_left_y":2144,"width":691,"height":50},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"616cc6e87003484485d6d88b16d24f15","type":"text","conversion_output":true,"text":"- Current back pain intensity and duration","text_display":"\n- Current back pain intensity and duration","confidence":1,"confidence_rate":1},{"cnt":[[434,2230],[1865,2230],[1865,2277],[434,2277]],"region":{"top_left_x":433,"top_left_y":2230,"width":1432,"height":48},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"74ba95436ffc4414b51883bdab520096","type":"text","conversion_output":true,"text":"- Diagnosis of serious mental health disorders and related treatment; 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a score of greater than or equal to 3 will lead to additional screening for","text_display":" administered; a score of greater than or equal to 3 will lead to additional screening for","confidence":0.99951171875,"confidence_rate":0.9999949649559944},{"cnt":[[494,2378],[1727,2378],[1727,2430],[494,2430]],"region":{"top_left_x":494,"top_left_y":2378,"width":1234,"height":52},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"776e0fb012ee478a8d973556667128c7","type":"text","conversion_output":true,"text":"suicidality. 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Those who indicate having done so at least weekly will receive additional","confidence":1,"confidence_rate":1},{"cnt":[[494,587],[1876,587],[1876,638],[494,638]],"region":{"top_left_x":494,"top_left_y":586,"width":1382,"height":53},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"505e4750f546458a89fed8586deb85e6","type":"text","conversion_output":true,"text":"screening: the 10-item Alcohol Use Disorders Identification Test (AUDIT) for alcohol. \\({ }^{128}\\)","text_display":" screening: the 10-item Alcohol Use Disorders Identification Test (AUDIT) for alcohol. \\({ }^{128}\\)","confidence":0.98291015625,"confidence_rate":0.9998276392506249},{"cnt":[[494,640],[1738,640],[1738,690],[494,690]],"region":{"top_left_x":494,"top_left_y":640,"width":1245,"height":50},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"da7becb99ca449129b00577fcd9d9981","type":"text","conversion_output":true,"text":"Scores of greater than or equal to 20 on the AUDIT is exclusionary and warrants","text_display":" Scores of greater than or equal to 20 on the AUDIT is exclusionary and warrants","confidence":1,"confidence_rate":1},{"cnt":[[494,690],[1800,690],[1800,741],[494,741]],"region":{"top_left_x":494,"top_left_y":689,"width":1307,"height":53},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"18683d3eb2784c4b836bd1067ae36177","type":"text","conversion_output":true,"text":"referral. 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Participants undergoing screening assessment via","text_display":" (in-person only) will be collected. 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These will also ensure","text_display":" baseline assessments are performed against which to measure the study outcome. These will also ensure","confidence":1,"confidence_rate":1},{"cnt":[[245,455],[1222,455],[1222,501],[245,501]],"region":{"top_left_x":244,"top_left_y":455,"width":979,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"95271259169147e598b37a874388a148","type":"text","conversion_output":true,"text":"the groups are balanced with respect to baseline characteristics.","text_display":" the groups are balanced with respect to baseline characteristics.","confidence":1,"confidence_rate":1},{"cnt":[[245,554],[1706,554],[1706,604],[245,604]],"region":{"top_left_x":244,"top_left_y":554,"width":1462,"height":50},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"96a9a85b9f364870ba1621c0e57cf46f","type":"text","conversion_output":true,"text":"Primary and secondary outcomes will be measured using web-based, self-report questionnaires","text_display":"\n\nPrimary and secondary outcomes will be measured using web-based, self-report questionnaires","confidence":1,"confidence_rate":1},{"cnt":[[245,606],[1115,606],[1115,651],[245,651]],"region":{"top_left_x":244,"top_left_y":605,"width":872,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"72288dc4ce2e4b3cbec14e0fd227dae9","type":"text","conversion_output":true,"text":"administered free of provider and investigator influence.","text_display":" administered free of provider and investigator influence.","confidence":0.9990234375,"confidence_rate":0.9999842414201705},{"cnt":[[241,705],[632,705],[632,750],[241,750]],"region":{"top_left_x":240,"top_left_y":704,"width":392,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6177929e30134b0d8896787a51fa2747","type":"section_header","conversion_output":false,"children_ids":["956c4006ae2547aaaf9af856c6ce053f"],"text":"","text_display":""},{"cnt":[[245,709],[629,709],[629,746],[245,746]],"region":{"top_left_x":244,"top_left_y":708,"width":386,"height":38},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"956c4006ae2547aaaf9af856c6ce053f","type":"text","conversion_output":true,"parent_id":"6177929e30134b0d8896787a51fa2747","text":"Baseline characteristics","text_display":"\n\n\\section*{Baseline characteristics}","confidence":1,"confidence_rate":1},{"cnt":[[245,756],[1815,756],[1815,804],[245,804]],"region":{"top_left_x":244,"top_left_y":756,"width":1572,"height":48},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9310b5d195ad4e5caed6987ad12ec37b","type":"text","conversion_output":true,"text":"Important baseline characteristics (e.g., demographics, past healthcare use, COVID-19 impact \\({ }^{190}\\), LBP","text_display":"\n\nImportant baseline characteristics (e.g., demographics, past healthcare use, COVID-19 impact \\({ }^{190}\\), LBP","confidence":0.9912109375,"confidence_rate":0.9999245505889836},{"cnt":[[245,804],[1699,804],[1699,853],[245,853]],"region":{"top_left_x":244,"top_left_y":803,"width":1456,"height":50},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7688ee12270543bc8812afbf58a414b8","type":"text","conversion_output":true,"text":"duration, prior episodes of LBP, visual trajectory questionnaire for pain \\({ }^{186}\\), Quebec Task Force","text_display":" duration, prior episodes of LBP, visual trajectory questionnaire for pain \\({ }^{186}\\), Quebec Task Force","confidence":0.9965848922729492,"confidence_rate":0.9999694562475565},{"cnt":[[245,855],[1833,855],[1833,904],[245,904]],"region":{"top_left_x":244,"top_left_y":855,"width":1589,"height":50},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"40216f75d6ca4924a89a9758d58d5fe8","type":"text","conversion_output":true,"text":"classification of spinal disorders \\({ }^{133}\\) ) will be collected through web-based, self-report questionnaires and","text_display":" classification of spinal disorders \\({ }^{133}\\) ) will be collected through web-based, self-report questionnaires and","confidence":1,"confidence_rate":1},{"cnt":[[245,907],[1779,907],[1779,956],[245,956]],"region":{"top_left_x":244,"top_left_y":906,"width":1535,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"65904a3292524b89a09842b6170923fa","type":"text","conversion_output":true,"text":"the screening provider's medical history and physical exam. Baseline measures included in the NIH","text_display":" the screening provider's medical history and physical exam. 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These items","text_display":" activities, and functional status, using 9 items of the 29 -item PROMIS short form. These items","confidence":0.9728410243988037,"confidence_rate":0.9997402733838853},{"cnt":[[370,1315],[1790,1315],[1790,1360],[370,1360]],"region":{"top_left_x":369,"top_left_y":1314,"width":1421,"height":46},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c3d587b32e734320bf413a2e1e16369a","type":"text","conversion_output":true,"text":"have substantial research support to validate their discriminatory and prognostic importance.","text_display":" have substantial research support to validate their discriminatory and prognostic importance.","confidence":1,"confidence_rate":1},{"cnt":[[370,1364],[1841,1364],[1841,1412],[370,1412]],"region":{"top_left_x":369,"top_left_y":1364,"width":1473,"height":48},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ecdb56e3b9aa4cea9f5393169373eed9","type":"text","conversion_output":true,"text":"Scores on the 9 PROMIS-based items yielding Impact Stratification range from 8 (least impact)","text_display":" Scores on the 9 PROMIS-based items yielding Impact Stratification range from 8 (least impact)","confidence":0.99951171875,"confidence_rate":0.9999953038523912},{"cnt":[[370,1409],[767,1409],[767,1463],[370,1463]],"region":{"top_left_x":369,"top_left_y":1409,"width":398,"height":55},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4009d26ce219434397616b173557c4d0","type":"text","conversion_output":true,"text":"to 50 (greatest impact). \\({ }^{191}\\)","text_display":" to 50 (greatest impact). \\({ }^{191}\\)","confidence":1,"confidence_rate":1},{"cnt":[[309,1500],[1775,1500],[1775,1549],[309,1549]],"region":{"top_left_x":309,"top_left_y":1499,"width":1466,"height":51},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"898277612f6b4f3bbd406f28de851118","type":"text","conversion_output":true,"text":"- LBP Intensity: participants will be asked to rate their average LBP over the last week on an","text_display":"\n- LBP Intensity: participants will be asked to rate their average LBP over the last week on an","confidence":1,"confidence_rate":1},{"cnt":[[370,1551],[1824,1551],[1824,1596],[370,1596]],"region":{"top_left_x":369,"top_left_y":1551,"width":1456,"height":46},"line":24,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"981ed34e747b4f2ba79e03a327967c28","type":"text","conversion_output":true,"text":"ordinal 11-box NRS ( \\(0=\\) no LBP, 10=the worst LBP possible). Several studies have shown that","text_display":" ordinal 11-box NRS ( \\(0=\\) no LBP, 10=the worst LBP possible). Several studies have shown that","confidence":0.5113530246346254,"confidence_rate":0.9932481987849624},{"cnt":[[370,1598],[1762,1598],[1762,1648],[370,1648]],"region":{"top_left_x":369,"top_left_y":1598,"width":1393,"height":50},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d4f296b74290494d84b7eb0423520d22","type":"text","conversion_output":true,"text":"ordinal pain scale measures perform as well as the \\(10- cm\\) Visual Analog Scale (VAS), \\({ }^{134}\\) a","text_display":" ordinal pain scale measures perform as well as the \\(10- cm\\) Visual Analog Scale (VAS), \\({ }^{134}\\) a","confidence":0.9902429580688477,"confidence_rate":0.9999108680291139},{"cnt":[[370,1646],[1876,1646],[1876,1697],[370,1697]],"region":{"top_left_x":369,"top_left_y":1645,"width":1507,"height":53},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0d6b85aa68aa4d0190f41d680d36503e","type":"text","conversion_output":true,"text":"simple, frequently used valid assessment of variation in pain intensity \\({ }^{119135}\\) and a reliable measure","text_display":" simple, frequently used valid assessment of variation in pain intensity \\({ }^{119135}\\) and a reliable measure","confidence":0.98828125,"confidence_rate":0.9998983848549613},{"cnt":[[370,1697],[1803,1697],[1803,1747],[370,1747]],"region":{"top_left_x":369,"top_left_y":1697,"width":1434,"height":50},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d9c6d1add6b449ccb98d0cb2976bd973","type":"text","conversion_output":true,"text":"of treatment efficacy. \\({ }^{136}\\) The advantage of the 11-box scale over the VAS is that it is easier to","text_display":" of treatment efficacy. \\({ }^{136}\\) The advantage of the 11-box scale over the VAS is that it is easier to","confidence":0.97705078125,"confidence_rate":0.9997927299514795},{"cnt":[[370,1749],[741,1749],[741,1794],[370,1794]],"region":{"top_left_x":369,"top_left_y":1748,"width":373,"height":46},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"64114bb5130c4d418a35bc17384c0e0b","type":"text","conversion_output":true,"text":"administer and score. \\({ }^{119}\\)","text_display":" administer and score. \\({ }^{119}\\)","confidence":1,"confidence_rate":1},{"cnt":[[309,1837],[1858,1837],[1858,1884],[309,1884]],"region":{"top_left_x":309,"top_left_y":1836,"width":1550,"height":49},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"61c43923acae40d79827560491131765","type":"text","conversion_output":true,"text":"- Low back disability will be measured with the modified Roland Morris Disability Questionnaire,","text_display":"\n- Low back disability will be measured with the modified Roland Morris Disability Questionnaire,","confidence":1,"confidence_rate":1},{"cnt":[[370,1886],[1781,1886],[1781,1936],[370,1936]],"region":{"top_left_x":369,"top_left_y":1886,"width":1413,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cecddfefdf5a436bb57ede1c86fcd9b1","type":"text","conversion_output":true,"text":"a 24-item questionnaire that measures the degree to which the low back problem or leg pain","text_display":" a 24-item questionnaire that measures the degree to which the low back problem or leg pain","confidence":0.98486328125,"confidence_rate":0.999839460801426},{"cnt":[[370,1938],[1813,1938],[1813,1985],[370,1985]],"region":{"top_left_x":369,"top_left_y":1937,"width":1445,"height":49},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bc274f37bb094694bddef910a8e891ad","type":"text","conversion_output":true,"text":"restricts patients' daily activities. It has a high level of internal consistency, construct validity,","text_display":" restricts patients' daily activities. It has a high level of internal consistency, construct validity,","confidence":1,"confidence_rate":1},{"cnt":[[370,1985],[720,1985],[720,2035],[370,2035]],"region":{"top_left_x":369,"top_left_y":1985,"width":351,"height":50},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"dffa4a54baf843ab9f97c0e362fed3ab","type":"text","conversion_output":true,"text":"and responsiveness. \\({ }^{120}\\)","text_display":" and responsiveness. \\({ 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a","text_display":" will be used with the exception of the question on pain intensity which is collected elsewhere on a","confidence":1,"confidence_rate":1},{"cnt":[[370,2342],[1818,2342],[1818,2391],[370,2391]],"region":{"top_left_x":369,"top_left_y":2341,"width":1449,"height":51},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3450f44401eb46c8b804d90c14550511","type":"text","conversion_output":true,"text":"weekly basis. \\({ }^{73}\\) This includes the following measures: pain interference with normal activities,","text_display":" weekly basis. \\({ }^{73}\\) This includes the following measures: pain interference with normal activities,","confidence":1,"confidence_rate":1},{"cnt":[[370,2398],[1841,2398],[1841,2443],[370,2443]],"region":{"top_left_x":369,"top_left_y":2397,"width":1473,"height":46},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a3133972fef9406996c238144a9c7058","type":"text","conversion_output":true,"text":"physical function, anxiety, depression, fatigue, sleep disturbance and the ability to participate in","text_display":" physical function, anxiety, depression, fatigue, sleep disturbance and the ability to participate in","confidence":1,"confidence_rate":1},{"cnt":[[370,2445],[771,2445],[771,2486],[370,2486]],"region":{"top_left_x":369,"top_left_y":2444,"width":403,"height":42},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ac6d9f74309e47f4a77cde811f0a1b61","type":"text","conversion_output":true,"text":"social roles and activities.","text_display":" social roles and activities.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1878,2582],[1878,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":375,"height":37},"line":40,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"35b82710d2e84c399eeadd08355f3e58","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 45","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-46","page":46,"lines":[{"cnt":[[309,254],[1800,254],[1800,299],[309,299]],"region":{"top_left_x":309,"top_left_y":253,"width":1492,"height":46},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d592d05304734da39aa76a86a9b1306d","type":"text","conversion_output":true,"text":"- LBP frequency will be collected by asking participants to report the number of days LBP has","text_display":"\n- LBP frequency will be collected by asking participants to report the number of days LBP has","confidence":1,"confidence_rate":1},{"cnt":[[370,301],[924,301],[924,350],[370,350]],"region":{"top_left_x":369,"top_left_y":300,"width":555,"height":51},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6053e57f65df4d81b7c9bca83cffe98d","type":"text","conversion_output":true,"text":"been a problem in the past 7 days. \\({ }^{73}\\)","text_display":" been a problem in the past 7 days. \\({ }^{73}\\)","confidence":1,"confidence_rate":1},{"cnt":[[309,387],[1699,387],[1699,436],[309,436]],"region":{"top_left_x":309,"top_left_y":386,"width":1391,"height":51},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0025682399314a4db668e54fb3798080","type":"text","conversion_output":true,"text":"- OTC and prescription medication use for LBP, including class and frequency by class.","text_display":"\n- OTC and prescription medication use for LBP, including class and frequency by 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questions from the Institute for Medical Technology Assessment's productivity","confidence":1,"confidence_rate":1},{"cnt":[[370,709],[703,709],[703,758],[370,758]],"region":{"top_left_x":369,"top_left_y":708,"width":334,"height":51},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1f96ec62739d41f49a049b75d8cad10d","type":"text","conversion_output":true,"text":"cost questionnaire. \\({ }^{137}\\)","text_display":" cost questionnaire. \\({ }^{137}\\)","confidence":1,"confidence_rate":1},{"cnt":[[309,795],[1863,795],[1863,844],[309,844]],"region":{"top_left_x":309,"top_left_y":794,"width":1554,"height":51},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"83dd1df709f34b82a82704a49a5d982e","type":"text","conversion_output":true,"text":"- Physical exam objective outcome measures including QTF classification \\({ }^{133}\\), timed up and go test,","text_display":"\n- Physical exam objective outcome measures including QTF 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half","confidence":0.99951171875,"confidence_rate":0.9999955192715237},{"cnt":[[370,1021],[1785,1021],[1785,1068],[370,1068]],"region":{"top_left_x":369,"top_left_y":1020,"width":1417,"height":48},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1d28f22f7eaa4865b37c25e213b57ff6","type":"text","conversion_output":true,"text":"the days in the past 6 months, at least half the days in the past 6 months, every day or nearly","text_display":" the days in the past 6 months, at least half the days in the past 6 months, every day or nearly","confidence":0.998046875,"confidence_rate":0.9999815564452184},{"cnt":[[370,1066],[866,1066],[866,1111],[370,1111]],"region":{"top_left_x":369,"top_left_y":1065,"width":497,"height":46},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d4f300c816634cd794647a86481aeea1","type":"text","conversion_output":true,"text":"every day in the past 6 months).","text_display":" every day in the past 6 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Prior to training, prior to the start of the UG3 pilot phase, at the","text_display":" implementation in other settings. 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Questionnaires will include qualitative survey questions that address","text_display":" participating practitioners. 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The Pain Attitudes and Beliefs Scale","text_display":" confidence in the interventions and in delivering care remotely \\({ }^{189}\\). The Pain Attitudes and Beliefs Scale","confidence":1,"confidence_rate":1},{"cnt":[[245,1109],[1790,1109],[1790,1158],[245,1158]],"region":{"top_left_x":244,"top_left_y":1108,"width":1546,"height":51},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5d395404dfd64f52b964d3b985fb1efe","type":"text","conversion_output":true,"text":"\\(( PABS )^{43}\\) and additional questions regarding practitioner confidence (using a \\(0-10 NRS\\) ) will also be","text_display":" \\(( PABS )^{43}\\) and additional questions regarding practitioner confidence (using a \\(0-10 NRS\\) ) will also be","confidence":0.6424116051424984,"confidence_rate":0.9962881995126291},{"cnt":[[245,1162],[1104,1162],[1104,1210],[245,1210]],"region":{"top_left_x":244,"top_left_y":1162,"width":861,"height":48},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"22533393a64a4922b2edeef88f945db7","type":"text","conversion_output":true,"text":"assessed quantitatively in the self-report questionnaires.","text_display":" assessed quantitatively in the self-report questionnaires.","confidence":1,"confidence_rate":1},{"cnt":[[245,1263],[1811,1263],[1811,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1263,"width":1568,"height":46},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"90d9f555e9b747c2aec441ad159a4ae2","type":"text","conversion_output":true,"text":"Qualitative data will also be collected from purposeful samples of health providers' and health system","text_display":"\n\nQualitative data will also be collected from purposeful samples of health providers' and health system","confidence":1,"confidence_rate":1},{"cnt":[[245,1313],[1794,1313],[1794,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1312,"width":1550,"height":48},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8456014476404068a032b960054a281f","type":"text","conversion_output":true,"text":"leaders using data collection methods that meet their needs and preferences (e.g., qualitative surveys,","text_display":" leaders using data collection methods that meet their needs and preferences (e.g., qualitative surveys,","confidence":1,"confidence_rate":1},{"cnt":[[245,1362],[1785,1362],[1785,1412],[245,1412]],"region":{"top_left_x":244,"top_left_y":1362,"width":1542,"height":50},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"953fc336450f434f9609dacc9b56d329","type":"text","conversion_output":true,"text":"interviews and field notes). Additional details regarding assessment of implementation measure data","text_display":" interviews and field notes). Additional details regarding assessment of implementation measure data","confidence":1,"confidence_rate":1},{"cnt":[[245,1414],[1021,1414],[1021,1463],[245,1463]],"region":{"top_left_x":244,"top_left_y":1413,"width":777,"height":51},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"031d3af44004421b8b9286896e539397","type":"text","conversion_output":true,"text":"collection is provided in the manual of operations.","text_display":" collection is provided in the manual of operations.","confidence":1,"confidence_rate":1},{"cnt":[[243,1525],[771,1525],[771,1575],[243,1575]],"region":{"top_left_x":242,"top_left_y":1525,"width":530,"height":50},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b2d3582964014be2a7dd552fad15a861","type":"section_header","conversion_output":false,"children_ids":["57e23ae4ec234cf38f48a44ee0e1f3fb"],"text":"","text_display":""},{"cnt":[[249,1530],[767,1530],[767,1571],[249,1571]],"region":{"top_left_x":249,"top_left_y":1529,"width":518,"height":42},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"57e23ae4ec234cf38f48a44ee0e1f3fb","type":"text","conversion_output":true,"parent_id":"b2d3582964014be2a7dd552fad15a861","text":"7. 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Moderate: minimal, local, or non-invasive intervention indicated; moderate impact on ADL.","confidence":1,"confidence_rate":1},{"cnt":[[245,672],[1833,672],[1833,718],[245,718]],"region":{"top_left_x":244,"top_left_y":672,"width":1589,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"658ccd063c4547edab74ca63f697119e","type":"text","conversion_output":true,"text":"3. Severe: significant symptoms requiring invasive intervention; subject seeks medical attention, needs","text_display":"\n3. Severe: significant symptoms requiring invasive intervention; subject seeks medical attention, needs","confidence":1,"confidence_rate":1},{"cnt":[[245,718],[677,718],[677,763],[245,763]],"region":{"top_left_x":244,"top_left_y":717,"width":433,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8b5b22a4573a488f923d9c2f6b68d5fd","type":"text","conversion_output":true,"text":"major assistance with ADL.","text_display":" major assistance with ADL.","confidence":1,"confidence_rate":1},{"cnt":[[245,804],[1848,804],[1848,851],[245,851]],"region":{"top_left_x":244,"top_left_y":803,"width":1604,"height":48},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"732715e097144217adcd33d78cea2d56","type":"text","conversion_output":true,"text":"We will measure and compare rates of AEs across the four treatment arms. We will specifically look for","text_display":"\n\nWe will measure and compare rates of AEs across the four treatment arms. We will specifically look for","confidence":1,"confidence_rate":1},{"cnt":[[245,851],[1725,851],[1725,896],[245,896]],"region":{"top_left_x":244,"top_left_y":850,"width":1482,"height":46},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ab0494e254094561bcd8eb75f58783b4","type":"text","conversion_output":true,"text":"common treatment-related AEs that include: LBP, soreness at the treatment site, gastrointestinal","text_display":" common treatment-related AEs that include: LBP, soreness at the treatment site, gastrointestinal","confidence":1,"confidence_rate":1},{"cnt":[[245,894],[1757,894],[1757,939],[245,939]],"region":{"top_left_x":244,"top_left_y":893,"width":1514,"height":46},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"17ffb099d08f400fafbd4b5f49502409","type":"text","conversion_output":true,"text":"symptoms, emotional discomfort, and other events. We will capture AEs prospectively from study","text_display":" symptoms, emotional discomfort, and other events. We will capture AEs prospectively from study","confidence":0.99951171875,"confidence_rate":0.9999950666738041},{"cnt":[[245,937],[1800,937],[1800,982],[245,982]],"region":{"top_left_x":244,"top_left_y":936,"width":1557,"height":46},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"18370ce407574fdda5b4c71be907b72a","type":"text","conversion_output":true,"text":"participants through monthly surveys and at in-person/videoconference/telephone visits. Each unique","text_display":" participants through monthly surveys and at in-person/videoconference/telephone visits. Each unique","confidence":1,"confidence_rate":1},{"cnt":[[245,1026],[245,980],[1549,982],[1549,1028]],"region":{"top_left_x":244,"top_left_y":979,"width":1306,"height":50},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34d8693581404a8ba213ff416699f429","type":"text","conversion_output":true,"text":"occurrence will receive a separate ID in order to avoid duplication in documentation.","text_display":" occurrence will receive a separate ID in order to avoid duplication in documentation.","confidence":1,"confidence_rate":1},{"cnt":[[245,1070],[1807,1070],[1807,1115],[245,1115]],"region":{"top_left_x":244,"top_left_y":1069,"width":1563,"height":47},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"81247c8ae7274bc0b0543f283e61dbbb","type":"text","conversion_output":true,"text":"SAE is generally defined as any untoward medical occurrence that results in death, is life threatening,","text_display":"\n\nSAE is generally defined as any untoward medical occurrence that results in death, is life threatening,","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1764,1113],[1764,1158],[245,1158]],"region":{"top_left_x":244,"top_left_y":1112,"width":1520,"height":47},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"edf9872294224b608d35bb40e20355ad","type":"text","conversion_output":true,"text":"requires inpatient hospitalization or prolongation of existing hospitalization, results in persistent or","text_display":" requires inpatient hospitalization or prolongation of existing hospitalization, results in persistent or","confidence":1,"confidence_rate":1},{"cnt":[[245,1156],[1390,1156],[1390,1201],[245,1201]],"region":{"top_left_x":244,"top_left_y":1155,"width":1147,"height":46},"line":19,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"eedc183461b54d3ca94637aa27a4085d","type":"text","conversion_output":true,"text":"significant disability/incapacity, or is a congenital anomaly or birth defect.","text_display":" significant disability/incapacity, or is a congenital anomaly or birth defect.","confidence":1,"confidence_rate":1},{"cnt":[[245,1244],[1863,1244],[1863,1291],[245,1291]],"region":{"top_left_x":244,"top_left_y":1243,"width":1619,"height":49},"line":20,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cbbab74c7de540e4ae598674e666fc02","type":"text","conversion_output":true,"text":"We will collect SAEs both passively through ad hoc reporting and through systematic evaluation at study","text_display":"\n\nWe will collect SAEs both passively through ad hoc reporting and through systematic evaluation at study","confidence":1,"confidence_rate":1},{"cnt":[[245,1289],[1858,1289],[1858,1334],[245,1334]],"region":{"top_left_x":244,"top_left_y":1289,"width":1615,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f06df5ee97ea44fab4d2be2eeb3d14f2","type":"text","conversion_output":true,"text":"visits. Given the nature of the interventions we do not anticipate any specific treatment-related SAEs and","text_display":" visits. 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In 2021, the NIH statistician overseeing the trial raised the","text_display":" disability over twelve months. 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statistical test that","text_display":" publications for presenting our main results and have revised the primary statistical test that","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1674,1113],[1674,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1430,"height":55},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c1951f6f9787447fbaa2df29b0b81f1a","type":"text","conversion_output":true,"text":"would be used to evaluate differences in mean outcomes across the treatment groups.","text_display":" would be used to evaluate differences in mean outcomes across the treatment groups.","confidence":1,"confidence_rate":1},{"cnt":[[245,1162],[1869,1162],[1869,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1626,"height":52},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"80386c5c1eed402da8580ddf899f00e3","type":"text","conversion_output":true,"text":"Specifically, rather than conduct individual tests of SMT alone, SSM alone, and the combination","text_display":" Specifically, rather than conduct individual tests of SMT alone, SSM alone, and the combination","confidence":1,"confidence_rate":1},{"cnt":[[245,1212],[1833,1212],[1833,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":1589,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d7325ef43cda480a912e27da3e45377a","type":"text","conversion_output":true,"text":"against medical care with adoption of a multiple comparisons correction for three tests we will","text_display":" against medical care with adoption of a multiple comparisons correction for three tests we 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estimation of key group comparisons using Fishers least significant","confidence":1,"confidence_rate":1},{"cnt":[[245,1354],[1841,1354],[1841,1405],[245,1405]],"region":{"top_left_x":244,"top_left_y":1353,"width":1598,"height":53},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a3d0aaa9a79542d3b5b60698c02f5f88","type":"text","conversion_output":true,"text":"difference methods to construct individual nominal \\(95 \\%\\) confidence intervals with reporting of","text_display":" difference methods to construct individual nominal \\(95 \\%\\) confidence intervals with reporting of","confidence":0.99853515625,"confidence_rate":0.9999854860688677},{"cnt":[[245,1401],[1818,1401],[1818,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1400,"width":1574,"height":55},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f617d2f520724311b33088b9869afefb","type":"text","conversion_output":true,"text":"the induced simultaneous coverage. These methods will be used for primary analysis of the 3","text_display":" the induced simultaneous coverage. These methods will be used for primary analysis of the 3","confidence":1,"confidence_rate":1},{"cnt":[[245,1452],[1422,1452],[1422,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1452,"width":1179,"height":50},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"067171a15288432eb7d35ccf35efde28","type":"text","conversion_output":true,"text":"primary effectiveness outcomes : LBP-Impact and pain and disability.","text_display":" primary effectiveness outcomes : LBP-Impact and pain and disability.","confidence":0.99951171875,"confidence_rate":0.9999933096045984},{"cnt":[[245,1547],[1863,1547],[1863,1601],[245,1601]],"region":{"top_left_x":244,"top_left_y":1546,"width":1619,"height":55},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ad633dfcb518454aad1731c9a01c42b9","type":"text","conversion_output":true,"text":"We plan to present principal findings in two key publications. The first publication would focus","text_display":"\n\nWe plan to present principal findings in two key publications. 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A","text_display":" recovery at 6 -months (previously a primary outcome) as one of the secondary outcomes. A","confidence":0.7873163223266602,"confidence_rate":0.9975122124253011},{"cnt":[[245,1691],[1824,1691],[1824,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1690,"width":1581,"height":53},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d5ab4565dd5749bfb96d14d0c9aa89c4","type":"text","conversion_output":true,"text":"second paper will focus on LBP Impact averaged over months 10-12 as the primary outcome.","text_display":" second paper will focus on LBP Impact averaged over months 10-12 as the primary outcome.","confidence":0.9585733413696289,"confidence_rate":0.9995451658060155},{"cnt":[[236,1779],[1523,1779],[1523,1843],[236,1843]],"region":{"top_left_x":236,"top_left_y":1778,"width":1288,"height":66},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7ecdee932b274e0a909b53b7bfc68556","type":"section_header","conversion_output":false,"children_ids":["913d75e2ffef43dab8aadf0703ceaa15"],"text":"","text_display":""},{"cnt":[[245,1783],[1517,1783],[1517,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1783,"width":1273,"height":54},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"913d75e2ffef43dab8aadf0703ceaa15","type":"text","conversion_output":true,"parent_id":"7ecdee932b274e0a909b53b7bfc68556","text":"Modifications to Statistical Analysis Plan Regarding Primary Outcome","text_display":"\n\n\\section*{Modifications to Statistical Analysis Plan Regarding Primary Outcome}","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[556,1835],[556,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":313,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8f259a6da96c461bbd6f40215719c314","type":"text","conversion_output":true,"text":"(edited July 2021)","text_display":"\n(edited July 2021)","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1738,1929],[1738,1983],[245,1983]],"region":{"top_left_x":244,"top_left_y":1929,"width":1495,"height":55},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ab140e9c6d454fd784f35ba3c2d1870a","type":"text","conversion_output":true,"text":"In consultation with the NCCIH program staff and DSMB in the Spring of 2021 we have","text_display":"\nIn consultation with the NCCIH program staff and DSMB in the Spring of 2021 we have","confidence":1,"confidence_rate":1},{"cnt":[[245,1977],[1794,1977],[1794,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1976,"width":1550,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1332f09240564714a22e3f44bb45efa7","type":"text","conversion_output":true,"text":"changed our primary outcome for assessment of treatment impacts on chronicity prevention.","text_display":" changed our primary outcome for assessment of treatment impacts on chronicity prevention.","confidence":1,"confidence_rate":1},{"cnt":[[245,2024],[1846,2024],[1846,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2023,"width":1602,"height":55},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7bcd2cb32df24ab0bb698efd3ee6e210","type":"text","conversion_output":true,"text":"Specifically, we have replaced our original NIH Task Force on Research Standards for Chronic","text_display":" Specifically, we have replaced our original NIH Task Force on Research Standards for Chronic","confidence":1,"confidence_rate":1},{"cnt":[[245,2073],[1798,2073],[1798,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2073,"width":1555,"height":52},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6f877670ccc94742a901b55134a40f08","type":"text","conversion_output":true,"text":"LBP (referred to as RTF) dichotomous chronicity measure with the RTF quantitative impact","text_display":" LBP (referred to as RTF) dichotomous chronicity measure with the RTF quantitative impact","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[1828,2123],[1828,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2122,"width":1585,"height":51},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e374bcdf79a9468e946d0da555f7f0d8","type":"text","conversion_output":true,"text":"measure. The LBP-Impact outcome measure is a subset of the Promise 29 measures, which is","text_display":" measure. The LBP-Impact outcome measure is a subset of the Promise 29 measures, which is","confidence":1,"confidence_rate":1},{"cnt":[[245,2170],[1807,2170],[1807,2219],[245,2219]],"region":{"top_left_x":244,"top_left_y":2169,"width":1563,"height":51},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"72f60cc340244b1d8a55892f64342105","type":"text","conversion_output":true,"text":"already being collected at baseline and every month during the follow-up year from the","text_display":" already being collected at baseline and every month during the follow-up year from the","confidence":1,"confidence_rate":1},{"cnt":[[245,2217],[1725,2217],[1725,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2217,"width":1482,"height":54},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f933f2f6672d49cdbe8a7fbb18cc8c55","type":"text","conversion_output":true,"text":"start of the trial. As a secondary outcome measure, we will compare differences across","text_display":" start of the trial. As a secondary outcome measure, we will compare differences across","confidence":1,"confidence_rate":1},{"cnt":[[245,2264],[1706,2264],[1706,2318],[245,2318]],"region":{"top_left_x":244,"top_left_y":2264,"width":1462,"height":55},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4cf59cb1bf4347d2a745bf8e73969d37","type":"text","conversion_output":true,"text":"treatment groups in the distribution of patients with mild, moderate, and severe impact.","text_display":" treatment groups in the distribution of patients with mild, moderate, and severe impact.","confidence":1,"confidence_rate":1},{"cnt":[[236,2355],[1620,2355],[1620,2419],[236,2419]],"region":{"top_left_x":236,"top_left_y":2354,"width":1384,"height":66},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"eb3b436112c342a682a5445c22799492","type":"section_header","conversion_output":false,"children_ids":["ab42b780da534f8a9fb3e554755ae2f1"],"text":"","text_display":""},{"cnt":[[245,2363],[1611,2363],[1611,2413],[245,2413]],"region":{"top_left_x":244,"top_left_y":2363,"width":1368,"height":50},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ab42b780da534f8a9fb3e554755ae2f1","type":"text","conversion_output":true,"parent_id":"eb3b436112c342a682a5445c22799492","text":"Modifications to Statistical Analysis Plan in Response to COVID-19 Impacts","text_display":"\n\n\\section*{Modifications to Statistical Analysis Plan in Response to COVID-19 Impacts}","confidence":0.99951171875,"confidence_rate":0.999993817734324},{"cnt":[[245,2411],[608,2411],[608,2460],[245,2460]],"region":{"top_left_x":244,"top_left_y":2410,"width":365,"height":50},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0193a50e078e4783b11339bdea072c5c","type":"text","conversion_output":true,"text":"(edited August 2020)","text_display":"\n(edited August 2020)","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"a592940dcd434a0a9c447e55cb04d42d","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 57","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-58","page":58,"lines":[{"cnt":[[245,299],[1815,299],[1815,350],[245,350]],"region":{"top_left_x":244,"top_left_y":298,"width":1572,"height":53},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c1a354fc106547ae8fe6fd11f45073de","type":"text","conversion_output":true,"text":"In Spring 2020 we suspended new enrollment into our study due to the COVID-19 pandemic.","text_display":"\n\nIn Spring 2020 we suspended new enrollment into our study due to the COVID-19 pandemic.","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1846,348],[1846,400],[245,400]],"region":{"top_left_x":244,"top_left_y":348,"width":1602,"height":52},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"992b0b55d28343c8910b518ceb24f565","type":"text","conversion_output":true,"text":"We continue to follow our participants and to maintain high-quality data collection. In order to","text_display":" We continue to follow our participants and to maintain high-quality data collection. In order to","confidence":1,"confidence_rate":1},{"cnt":[[245,397],[1775,397],[1775,445],[245,445]],"region":{"top_left_x":244,"top_left_y":397,"width":1531,"height":48},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2415c23266ad46be986d821e2d65afc0","type":"text","conversion_output":true,"text":"resume trial enrollment, we are making adjustments to both care delivery and research data","text_display":" resume trial enrollment, we are making adjustments to both care delivery and research data","confidence":1,"confidence_rate":1},{"cnt":[[245,443],[1858,443],[1858,494],[245,494]],"region":{"top_left_x":244,"top_left_y":442,"width":1615,"height":53},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8dd010f9b144410b8e6f2c3120de38e1","type":"text","conversion_output":true,"text":"collection, and we have a modification to the enrollment and randomization that is responsive to","text_display":" collection, and we have a modification to the enrollment and randomization that is responsive to","confidence":1,"confidence_rate":1},{"cnt":[[245,492],[1384,492],[1384,544],[245,544]],"region":{"top_left_x":244,"top_left_y":491,"width":1140,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"214d6c1f871b4e0391d55aa650a05733","type":"text","conversion_output":true,"text":"risk mitigation. The key design and analysis modifications include:","text_display":" risk mitigation. The key design and analysis modifications include:","confidence":1,"confidence_rate":1},{"cnt":[[305,541],[1815,541],[1815,595],[305,595]],"region":{"top_left_x":305,"top_left_y":541,"width":1511,"height":55},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b8f801dce71c4c7497fc92aca806b7f4","type":"text","conversion_output":true,"text":"- We will initially restart with restricted randomization to the MC and SSM groups. We","text_display":"\n- We will initially restart with restricted randomization to the MC and SSM groups. We","confidence":1,"confidence_rate":1},{"cnt":[[370,593],[1826,593],[1826,642],[370,642]],"region":{"top_left_x":369,"top_left_y":592,"width":1458,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c5797af8d4de423bbc715dc2c35b9ebb","type":"text","conversion_output":true,"text":"will resume full factorial randomization once it is safe and appropriate. Specifically, in","text_display":" will resume full factorial randomization once it is safe and appropriate. Specifically, in","confidence":1,"confidence_rate":1},{"cnt":[[370,640],[1740,640],[1740,690],[370,690]],"region":{"top_left_x":369,"top_left_y":640,"width":1372,"height":50},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0e4197b79e594bd88215504e36a12083","type":"text","conversion_output":true,"text":"order to restrict physical interaction, we will conduct both remote assessment and","text_display":" order to restrict physical interaction, we will conduct both remote assessment and","confidence":1,"confidence_rate":1},{"cnt":[[370,688],[1841,688],[1841,737],[370,737]],"region":{"top_left_x":369,"top_left_y":687,"width":1473,"height":50},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f69c0dae06234bc9a7157f74056756e3","type":"text","conversion_output":true,"text":"intervention in a partial randomization period during which participants are randomized","text_display":" intervention in a partial randomization period during which participants are randomized","confidence":1,"confidence_rate":1},{"cnt":[[370,735],[1824,735],[1824,784],[370,784]],"region":{"top_left_x":369,"top_left_y":734,"width":1456,"height":51},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cfa26780328641f1a92785d04cf68e1a","type":"text","conversion_output":true,"text":"only to Medical Care (MC) or Supported Self-Management (SSM). Although we hope","text_display":" only to Medical Care (MC) or Supported Self-Management (SSM). 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Since all possible randomization","text_display":" any future periods when physical contact is precluded. Since all possible randomization","confidence":1,"confidence_rate":1},{"cnt":[[370,924],[1867,924],[1867,978],[370,978]],"region":{"top_left_x":369,"top_left_y":923,"width":1498,"height":55},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dce8836437f64493b1494c1c732afde8","type":"text","conversion_output":true,"text":"groups contribute to the ultimate effect estimates, the partial randomization period data is","text_display":" groups contribute to the ultimate effect estimates, the partial randomization period data is","confidence":1,"confidence_rate":1},{"cnt":[[370,975],[1723,975],[1723,1025],[370,1025]],"region":{"top_left_x":369,"top_left_y":975,"width":1355,"height":50},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b6d8b135fe57404ba5cbc8ccc6471cab","type":"text","conversion_output":true,"text":"informative and can be combined with the pre-COVID data and the full factorial","text_display":" informative and can be combined with the pre-COVID data and the full factorial","confidence":1,"confidence_rate":1},{"cnt":[[370,1023],[1833,1023],[1833,1072],[370,1072]],"region":{"top_left_x":369,"top_left_y":1022,"width":1464,"height":51},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4c8d64c6098c44d69763b5de6001a00f","type":"text","conversion_output":true,"text":"randomization data. In order to account for potential period-effects, we will modify all","text_display":" randomization data. 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(please see below for details)","text_display":" strata. (please see below for details)","confidence":1,"confidence_rate":1},{"cnt":[[305,1558],[1863,1558],[1863,1609],[305,1609]],"region":{"top_left_x":305,"top_left_y":1557,"width":1558,"height":53},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"57caf97cdb7047238635525ad9360dfb","type":"text","conversion_output":true,"text":"- We have evaluated the impact on the power of our study subject to the potential for up to","text_display":"\n- We have evaluated the impact on the power of our study subject to the potential for up to","confidence":1,"confidence_rate":1},{"cnt":[[370,1607],[1751,1607],[1751,1656],[370,1656]],"region":{"top_left_x":369,"top_left_y":1607,"width":1382,"height":50},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c11da29d34714a558f5e97208bef38f4","type":"text","conversion_output":true,"text":"240 subjects enrolled during restricted randomization. In our original protocol we","text_display":" 240 subjects enrolled during restricted randomization. In our original protocol we","confidence":1,"confidence_rate":1},{"cnt":[[370,1654],[1779,1654],[1779,1704],[370,1704]],"region":{"top_left_x":369,"top_left_y":1654,"width":1410,"height":50},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ffc6e9425b044bc6853d3ad9aacb0226","type":"text","conversion_output":true,"text":"focused sample size on obtaining adequate power for the Aim 1 chronicity endpoint","text_display":" focused sample size on obtaining adequate power for the Aim 1 chronicity endpoint","confidence":1,"confidence_rate":1},{"cnt":[[370,1702],[1755,1702],[1755,1751],[370,1751]],"region":{"top_left_x":369,"top_left_y":1701,"width":1387,"height":50},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"42f85ac303894d8bbf6a04d832898ac0","type":"text","conversion_output":true,"text":"assuming treatment relative risks of 0.70 (a \\(30 \\%\\) relative reduction), no interaction","text_display":" assuming treatment relative risks of 0.70 (a \\(30 \\%\\) relative reduction), no interaction","confidence":0.990234375,"confidence_rate":0.9998967040569899},{"cnt":[[370,1749],[1738,1749],[1738,1798],[370,1798]],"region":{"top_left_x":369,"top_left_y":1748,"width":1370,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f09ce6eb4f384d84917f2a87281ce947","type":"text","conversion_output":true,"text":"between treatments, and a control rate of 0.20 . For this original scenario we used","text_display":" between treatments, and a control rate of 0.20 . For this original scenario we used","confidence":0.9951171875,"confidence_rate":0.99994621273915},{"cnt":[[370,1796],[1828,1796],[1828,1846],[370,1846]],"region":{"top_left_x":369,"top_left_y":1796,"width":1460,"height":50},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7550ba7192c1458cad8f93c3f535f940","type":"text","conversion_output":true,"text":"simulations to compute a power of \\(81 \\%\\) for either the overall SSM effect or the overall","text_display":" simulations to compute a power of \\(81 \\%\\) for either the overall SSM effect or the overall","confidence":1,"confidence_rate":1},{"cnt":[[370,1843],[1861,1843],[1861,1897],[370,1897]],"region":{"top_left_x":369,"top_left_y":1843,"width":1492,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3c62d92f045c45e88a217cf51dfd75c2","type":"text","conversion_output":true,"text":"SMT effect. With partial randomization and an upper bound of \\(n =240\\) subjects allocated","text_display":" SMT effect. With partial randomization and an upper bound of \\(n =240\\) subjects allocated","confidence":1,"confidence_rate":1},{"cnt":[[370,1893],[1852,1893],[1852,1944],[370,1944]],"region":{"top_left_x":369,"top_left_y":1892,"width":1483,"height":53},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"17e2960bb3f148238b56917b35f95a81","type":"text","conversion_output":true,"text":"during this period we obtain \\(78 \\%\\) power to detect an overall SSM effect and \\(77 \\%\\) power","text_display":" during this period we obtain \\(78 \\%\\) power to detect an overall SSM effect and \\(77 \\%\\) power","confidence":0.9990234375,"confidence_rate":0.9999897154250147},{"cnt":[[370,1942],[1818,1942],[1818,1992],[370,1992]],"region":{"top_left_x":369,"top_left_y":1942,"width":1449,"height":50},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"acba649a0e9b4150bd3915b502eb1db7","type":"text","conversion_output":true,"text":"to detect an overall SMT effect. Therefore, the impact of altering the design to permit","text_display":" to detect an overall SMT effect. Therefore, the impact of altering the design to permit","confidence":1,"confidence_rate":1},{"cnt":[[370,1989],[1807,1989],[1807,2039],[370,2039]],"region":{"top_left_x":369,"top_left_y":1989,"width":1438,"height":50},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"331af5da49404c9497e12219ba7928f8","type":"text","conversion_output":true,"text":"partial randomization is anticipated to have a minor reduction in power for our binary","text_display":" partial randomization is anticipated to have a minor reduction in power for our binary","confidence":1,"confidence_rate":1},{"cnt":[[370,2037],[1863,2037],[1863,2086],[370,2086]],"region":{"top_left_x":369,"top_left_y":2036,"width":1494,"height":51},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"124b02f281a94822a4a5a9ae4545a824","type":"text","conversion_output":true,"text":"endpoints. In addition, the planned design will result in a minimum of \\(n =30\\) per protocol","text_display":" endpoints. In addition, the planned design will result in a minimum of \\(n =30\\) per protocol","confidence":1,"confidence_rate":1},{"cnt":[[370,2084],[1828,2084],[1828,2136],[370,2136]],"region":{"top_left_x":369,"top_left_y":2083,"width":1460,"height":53},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"54748df161bc4fda93c5a71dc183f50b","type":"text","conversion_output":true,"text":"pre-COVID subjects in the SMT and SSM+SMT groups combined with a full factorial","text_display":" pre-COVID subjects in the SMT and SSM+SMT groups combined with a full factorial","confidence":1,"confidence_rate":1},{"cnt":[[370,2133],[1878,2133],[1878,2185],[370,2185]],"region":{"top_left_x":369,"top_left_y":2133,"width":1509,"height":52},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"828c353769914b1fa91a1d3067163cce","type":"text","conversion_output":true,"text":"randomization allocation of \\(n =188\\) will permit a total of \\(n =30+188=218\\) subject per group","text_display":" randomization allocation of \\(n =188\\) will permit a total of \\(n =30+188=218\\) subject per group","confidence":1,"confidence_rate":1},{"cnt":[[370,2183],[1755,2183],[1755,2232],[370,2232]],"region":{"top_left_x":369,"top_left_y":2182,"width":1387,"height":51},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"35eb2f9aa7394ffbaf7b84e8310c470f","type":"text","conversion_output":true,"text":"to evaluate mean differences in pain and disability scales across the four treatment","text_display":" to evaluate mean differences in pain and disability scales across the four treatment","confidence":1,"confidence_rate":1},{"cnt":[[370,2230],[1747,2230],[1747,2279],[370,2279]],"region":{"top_left_x":369,"top_left_y":2230,"width":1378,"height":50},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0dcf6e6a050b4997913755969a6767a3","type":"text","conversion_output":true,"text":"groups. For MC and SSM groups we expect to have an upper bound of \\(n =45\\) pre-","text_display":" groups. For MC and SSM groups we expect to have an upper bound of \\(n =45\\) pre","confidence":0.9443628787994385,"confidence_rate":0.999334584496532},{"cnt":[[370,2277],[1865,2277],[1865,2327],[370,2327]],"region":{"top_left_x":369,"top_left_y":2277,"width":1496,"height":50},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"88bbfe6af773455bbea519ee428912c9","type":"text","conversion_output":true,"text":"COVID, \\(n =120\\) partial randomization, and \\(n =188\\) full factorial randomization subjects or","text_display":"COVID, \\(n =120\\) partial randomization, and \\(n =188\\) full factorial randomization subjects or","confidence":0.92822265625,"confidence_rate":0.9992771192327227},{"cnt":[[370,2325],[1809,2325],[1809,2376],[370,2376]],"region":{"top_left_x":369,"top_left_y":2324,"width":1440,"height":53},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e37299c3ad11471487ff2a7d84610400","type":"text","conversion_output":true,"text":"\\(n =45+120+188=354\\) total subjects per group. Our original balanced allocation would","text_display":" \\(n =45+120+188=354\\) total subjects per group. Our original balanced allocation would","confidence":0.9970703125,"confidence_rate":0.9999666597894927},{"cnt":[[370,2374],[1154,2374],[1154,2426],[370,2426]],"region":{"top_left_x":369,"top_left_y":2374,"width":785,"height":52},"line":44,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6c9ce5bf253f47ac8db42b2dba3cbd67","type":"text","conversion_output":true,"text":"have produced \\(n =1180 / 4=295\\) subjects/group.","text_display":" have produced \\(n =1180 / 4=295\\) subjects/group.","confidence":0.982421875,"confidence_rate":0.999665443619117},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":45,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"0809eb4d1ea649c18f6959222c95deba","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 58","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-59","page":59,"lines":[{"cnt":[[243,251],[683,251],[683,303],[243,303]],"region":{"top_left_x":242,"top_left_y":251,"width":442,"height":52},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b47d4ecebcf942e1b2c69f5786d8b0ec","type":"section_header","conversion_output":false,"children_ids":["67b9a6b7bfa84aefbd79124c2072a248"],"text":"","text_display":""},{"cnt":[[247,254],[681,254],[681,299],[247,299]],"region":{"top_left_x":247,"top_left_y":253,"width":435,"height":46},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"67b9a6b7bfa84aefbd79124c2072a248","type":"text","conversion_output":true,"parent_id":"b47d4ecebcf942e1b2c69f5786d8b0ec","text":"Statistical Analysis Plan","text_display":"\n\n\\section*{Statistical Analysis Plan}","confidence":1,"confidence_rate":1},{"cnt":[[247,352],[1794,352],[1794,397],[247,397]],"region":{"top_left_x":247,"top_left_y":352,"width":1547,"height":46},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ac913268cc4a41f1bb2649c3dd6ddd85","type":"text","conversion_output":true,"text":"Introduction: A factorial trial is ideal when the two treatments under study are thought to act","text_display":"\n\nIntroduction: A factorial trial is ideal when the two treatments under study are thought to act","confidence":1,"confidence_rate":1},{"cnt":[[247,393],[1785,393],[1785,445],[247,445]],"region":{"top_left_x":247,"top_left_y":393,"width":1539,"height":52},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"169b6c45cc9b4741aad042db65294a8d","type":"text","conversion_output":true,"text":"independently via different mechanisms. \\({ }^{146}\\) Our interventions focus on a physical treatment","text_display":" independently via different mechanisms. \\({ }^{146}\\) Our interventions focus on a physical treatment","confidence":0.69580078125,"confidence_rate":0.9965842254401989},{"cnt":[[249,447],[1835,447],[1835,492],[249,492]],"region":{"top_left_x":249,"top_left_y":446,"width":1586,"height":46},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"94d4f6cdf72749e692fac642726fc9ab","type":"text","conversion_output":true,"text":"approach (SMT) and a psychological intervention (SSM) for addressing acute LBP. A factorial","text_display":" approach (SMT) and a psychological intervention (SSM) for addressing acute LBP. A factorial","confidence":1,"confidence_rate":1},{"cnt":[[249,494],[1867,494],[1867,539],[249,539]],"region":{"top_left_x":249,"top_left_y":494,"width":1618,"height":46},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"42dd47e5cd2b4908ae1271454e41c448","type":"text","conversion_output":true,"text":"design allows an efficient evaluation of each of these modalities using fewer subjects than would","text_display":" design allows an efficient evaluation of each of these modalities using fewer subjects than would","confidence":0.9843893051147461,"confidence_rate":0.9998457587111788},{"cnt":[[249,541],[1837,541],[1837,589],[249,589]],"region":{"top_left_x":249,"top_left_y":541,"width":1588,"height":48},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e2d5396212ce40fab3119c1b052ed435","type":"text","conversion_output":true,"text":"be required by separate trials. In addition, a crucial advantage of a factorial trial is the ability to","text_display":" be required by separate trials. In addition, a crucial advantage of a factorial trial is the ability to","confidence":1,"confidence_rate":1},{"cnt":[[249,591],[1751,591],[1751,638],[249,638]],"region":{"top_left_x":249,"top_left_y":590,"width":1502,"height":49},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3bab0c942ecb4befbd701087c6d1268d","type":"text","conversion_output":true,"text":"evaluate whether the beneficial effects of each treatment modality combine in an additive,","text_display":" evaluate whether the beneficial effects of each treatment modality combine in an additive,","confidence":1,"confidence_rate":1},{"cnt":[[247,632],[1611,632],[1611,685],[247,685]],"region":{"top_left_x":247,"top_left_y":631,"width":1365,"height":55},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0ccce1e7d1444ab9a82d3832a5bf2e99","type":"text","conversion_output":true,"text":"antagonistic, or synergistic fashion through evaluation of treatment interaction. \\({ }^{147}\\)","text_display":" antagonistic, or synergistic fashion through evaluation of treatment interaction. \\({ }^{147}\\)","confidence":1,"confidence_rate":1},{"cnt":[[247,735],[1828,735],[1828,780],[247,780]],"region":{"top_left_x":247,"top_left_y":734,"width":1582,"height":46},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7478b217e2d44f5ba2131d7e40c94e22","type":"text","conversion_output":true,"text":"The trial was originally powered to detect meaningful differences in two dichotomous primary","text_display":"\n\nThe trial was originally powered to detect meaningful differences in two dichotomous primary","confidence":1,"confidence_rate":1},{"cnt":[[249,782],[1663,782],[1663,827],[249,827]],"region":{"top_left_x":249,"top_left_y":782,"width":1414,"height":46},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b899ff949c1e4504a9a867cf59502ab0","type":"text","conversion_output":true,"text":"outcome measures, chronicity and recovery. These two outcomes are now secondary","text_display":" outcome measures, chronicity and recovery. These two outcomes are now secondary","confidence":1,"confidence_rate":1},{"cnt":[[249,829],[642,829],[642,870],[249,870]],"region":{"top_left_x":249,"top_left_y":829,"width":394,"height":42},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bf2779632c734ff6ac28b8b4841a0d26","type":"text","conversion_output":true,"text":"effectiveness measures.","text_display":" effectiveness 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9.1: The \\(2 \\times 2\\) factorial design","text_display":"","confidence":0.9990234375,"confidence_rate":0.9999777947999976},{"cnt":[[284,973],[428,973],[428,1012],[284,1012]],"region":{"top_left_x":283,"top_left_y":973,"width":145,"height":39},"line":16,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"789ed8fbac6c4df5a0caa8ce8b6aec53","type":"text","conversion_output":false,"parent_id":"70ba399ee23e468d94426a71fef1c481","text":"(n=1000)","text_display":"","confidence":0.97607421875,"confidence_rate":0.9981389146127377},{"cnt":[[284,1014],[913,1014],[913,1558],[284,1558]],"region":{"top_left_x":283,"top_left_y":1014,"width":631,"height":544},"line":17,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c1c3aacc2230408f9212f032eb1ab21f","type":"table","conversion_output":true,"parent_id":"2c471355022c42b6b0cc9b6cc5df66a7","selected_labels":["70ba399ee23e468d94426a71fef1c481"],"text":"\\begin{tabular}{|c|c|c|}\n\\hline & \\begin{tabular}{c} \nSMT \\\\\nIntervention\n\\end{tabular} & \\begin{tabular}{c} \nNo SMT \\\\\nIntervention\n\\end{tabular} \\\\\n\\hline \\begin{tabular}{c} \nSSM \\\\\nIntervention\n\\end{tabular} & \\begin{tabular}{c} \nSMT + SSM \\\\\nGroup A\n\\end{tabular} & \\begin{tabular}{c} \nSSM only \\\\\nGroup B\n\\end{tabular} \\\\\n\\hline \\begin{tabular}{c} \nNo SSM \\\\\nIntervention\n\\end{tabular} & Group C & \\begin{tabular}{l} \nGroup D \\\\\nSMT only \\\\\nUsual Medical \\\\\nCare\n\\end{tabular} \\\\\n\\hline\n\\end{tabular}","text_display":"\n\n\\begin{table}\n\\captionsetup{labelformat=empty}\n\\caption{Figure 9.1: The \\(2 \\times 2\\) factorial design (n=1000)}\n\\begin{tabular}{|c|c|c|}\n\\hline & \\begin{tabular}{c} \nSMT \\\\\nIntervention\n\\end{tabular} & \\begin{tabular}{c} \nNo SMT \\\\\nIntervention\n\\end{tabular} \\\\\n\\hline \\begin{tabular}{c} \nSSM \\\\\nIntervention\n\\end{tabular} & \\begin{tabular}{c} \nSMT + SSM \\\\\nGroup A\n\\end{tabular} & \\begin{tabular}{c} \nSSM only \\\\\nGroup B\n\\end{tabular} \\\\\n\\hline \\begin{tabular}{c} \nNo SSM \\\\\nIntervention\n\\end{tabular} & Group C & \\begin{tabular}{l} \nGroup D \\\\\nSMT only \\\\\nUsual Medical \\\\\nCare\n\\end{tabular} \\\\\n\\hline\n\\end{tabular}\n\\end{table}","confidence":0.30181022212701814,"confidence_rate":0.9964930936319344},{"cnt":[[967,879],[1807,879],[1807,924],[967,924]],"region":{"top_left_x":966,"top_left_y":878,"width":841,"height":46},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3b82b32f1a744d809e95ddbccdfbea54","type":"text","conversion_output":true,"text":"For the 3 quantitative primary outcomes collected","text_display":"\n\nFor the 3 quantitative primary outcomes collected","confidence":1,"confidence_rate":1},{"cnt":[[967,924],[1828,924],[1828,973],[967,973]],"region":{"top_left_x":966,"top_left_y":923,"width":863,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c82667b7af3d4933b77b942b0e77d949","type":"text","conversion_output":true,"text":"longitudinally, RMDQ, Pain NRS and LBP-Impact","text_display":" longitudinally, RMDQ, Pain NRS and LBP-Impact","confidence":1,"confidence_rate":1},{"cnt":[[967,975],[1837,975],[1837,1021],[967,1021]],"region":{"top_left_x":966,"top_left_y":975,"width":871,"height":46},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0862d1a44839410d9bb95cd021a22044","type":"text","conversion_output":true,"text":"we will conduct detailed analysis of the four groups","text_display":" we will conduct detailed analysis of the four groups","confidence":1,"confidence_rate":1},{"cnt":[[967,1023],[1721,1023],[1721,1068],[967,1068]],"region":{"top_left_x":966,"top_left_y":1022,"width":755,"height":46},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2934f2dd2f124f21b7c117ca06d42c3b","type":"text","conversion_output":true,"text":"formed by the factorial design since we have","text_display":" formed by the factorial design since we have","confidence":1,"confidence_rate":1},{"cnt":[[967,1070],[1841,1070],[1841,1117],[967,1117]],"region":{"top_left_x":966,"top_left_y":1069,"width":876,"height":49},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b289bf0b54c64cee880aa1d75846f657","type":"text","conversion_output":true,"text":"excellent power for such endpoints with our revised","text_display":" excellent power for such endpoints with our revised","confidence":0.99951171875,"confidence_rate":0.9999912786005654},{"cnt":[[967,1117],[1858,1117],[1858,1162],[967,1162]],"region":{"top_left_x":966,"top_left_y":1117,"width":893,"height":46},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bd049929c5e84644822ccdc29aa26dd6","type":"text","conversion_output":true,"text":"sample size of 1000 subjects. However, McAlister et","text_display":" sample size of 1000 subjects. However, McAlister et","confidence":1,"confidence_rate":1},{"cnt":[[967,1160],[1846,1160],[1846,1214],[967,1214]],"region":{"top_left_x":966,"top_left_y":1160,"width":880,"height":54},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"797de2de590249d5b1f1cf72ffe65c77","type":"text","conversion_output":true,"text":"al. \\({ }^{146}\\) comment that \"the most powerful analysis of a","text_display":" al. \\({ }^{146}\\) comment that \"the most powerful analysis of a","confidence":1,"confidence_rate":1},{"cnt":[[967,1212],[1807,1212],[1807,1261],[967,1261]],"region":{"top_left_x":966,"top_left_y":1211,"width":841,"height":51},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e4a31d7df7c9416ebbd95a24aaa8fda1","type":"text","conversion_output":true,"text":"factorial trial is performed at the margins\" and we","text_display":" factorial trial is performed at the margins\" and we","confidence":1,"confidence_rate":1},{"cnt":[[967,1263],[1790,1263],[1790,1308],[967,1308]],"region":{"top_left_x":966,"top_left_y":1263,"width":824,"height":46},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"008be243ec1443e1a4dd8e8f87f5c117","type":"text","conversion_output":true,"text":"adopt such an approach for our secondary binary","text_display":" adopt such an approach for our secondary binary","confidence":1,"confidence_rate":1},{"cnt":[[967,1311],[1785,1311],[1785,1356],[967,1356]],"region":{"top_left_x":966,"top_left_y":1310,"width":820,"height":46},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0f2e37724e6c4e9a82a7c8f8fca41d25","type":"text","conversion_output":true,"text":"chronicity and recovery outcomes. We explicitly","text_display":" chronicity and recovery outcomes. We explicitly","confidence":1,"confidence_rate":1},{"cnt":[[967,1358],[1803,1358],[1803,1403],[967,1403]],"region":{"top_left_x":966,"top_left_y":1357,"width":837,"height":46},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"53d905ee6a914ec39f82eae93d47d230","type":"text","conversion_output":true,"text":"define the separate treatment effects for SMT and","text_display":" define the separate treatment effects for SMT and","confidence":1,"confidence_rate":1},{"cnt":[[967,1405],[1858,1405],[1858,1450],[967,1450]],"region":{"top_left_x":966,"top_left_y":1405,"width":893,"height":46},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"87fa5487584a4d0db933821c8f62aa4b","type":"text","conversion_output":true,"text":"SSM as the overall or average treatment effect that is","text_display":" SSM as the overall or average treatment effect that is","confidence":1,"confidence_rate":1},{"cnt":[[967,1452],[1755,1452],[1755,1497],[967,1497]],"region":{"top_left_x":966,"top_left_y":1452,"width":790,"height":46},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"89bb864bdab34a51b79009ffb191351a","type":"text","conversion_output":true,"text":"obtained from pooling comparisons over strata","text_display":" obtained from pooling comparisons over strata","confidence":1,"confidence_rate":1},{"cnt":[[967,1500],[1785,1500],[1785,1549],[967,1549]],"region":{"top_left_x":966,"top_left_y":1499,"width":820,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0fc4285427e9465391782245eeddcc03","type":"text","conversion_output":true,"text":"defined by the other treatment approach (i.e., the","text_display":" defined by the other treatment approach (i.e., the","confidence":1,"confidence_rate":1},{"cnt":[[967,1549],[1863,1549],[1863,1596],[967,1596]],"region":{"top_left_x":966,"top_left_y":1549,"width":897,"height":48},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"222607c1f45e4c8484e3c3b340c8be8d","type":"text","conversion_output":true,"text":"SMT treatment effect obtained by pooling over strata","text_display":" SMT treatment effect obtained by pooling over strata","confidence":1,"confidence_rate":1},{"cnt":[[245,1594],[1867,1594],[1867,1644],[245,1644]],"region":{"top_left_x":244,"top_left_y":1594,"width":1623,"height":50},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5fa0fccf389a4909b30bd6eab43cf688","type":"text","conversion_output":true,"text":"with and without SSM). In particular, we define the parameter of interest as a linear combination","text_display":" with and without SSM). In particular, we define the parameter of interest as a linear combination","confidence":1,"confidence_rate":1},{"cnt":[[249,1646],[1824,1646],[1824,1691],[249,1691]],"region":{"top_left_x":249,"top_left_y":1645,"width":1576,"height":46},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f3b2f599f2cb4673be594e417b3c5180","type":"text","conversion_output":true,"text":"(contrast) of parameters from an appropriate regression model that acknowledges the potential","text_display":" (contrast) of parameters from an appropriate regression model that acknowledges the potential","confidence":1,"confidence_rate":1},{"cnt":[[247,1693],[1790,1693],[1790,1738],[247,1738]],"region":{"top_left_x":247,"top_left_y":1692,"width":1543,"height":47},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"76905e43ac8742aaa0185de6d0e448f4","type":"text","conversion_output":true,"text":"for SMT and SSM interaction. Therefore, our proposed analyses for binary outcomes do not","text_display":" for SMT and SSM interaction. Therefore, our proposed analyses for binary outcomes do not","confidence":0.9990234375,"confidence_rate":0.9999894942525209},{"cnt":[[247,1740],[1871,1740],[1871,1788],[247,1788]],"region":{"top_left_x":247,"top_left_y":1740,"width":1625,"height":48},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2776c6d3ffbc4d848763727cbcfe169f","type":"text","conversion_output":true,"text":"make any additive assumptions and is quite generally valid for creating meaningful overall effect","text_display":" make any additive assumptions and is quite generally valid for creating meaningful overall effect","confidence":1,"confidence_rate":1},{"cnt":[[247,1788],[1865,1788],[1865,1835],[247,1835]],"region":{"top_left_x":247,"top_left_y":1787,"width":1618,"height":48},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d7ab5f365bd147cda30150fde8ac6899","type":"text","conversion_output":true,"text":"summaries. Furthermore, by collecting detailed outcomes and health care utilization through one","text_display":" summaries. Furthermore, by collecting detailed outcomes and health care utilization through one","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1727,1835],[1727,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1484,"height":51},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed461528785b49348ab250f351f83fe3","type":"text","conversion_output":true,"text":"year we can conduct thorough mediation analyses and careful evaluation of concomitant","text_display":" year we can conduct thorough mediation analyses and careful evaluation of concomitant","confidence":0.9639015197753906,"confidence_rate":0.9995915706799788},{"cnt":[[245,1886],[419,1886],[419,1927],[245,1927]],"region":{"top_left_x":244,"top_left_y":1886,"width":175,"height":42},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c039183fcf324fd4a99068d4b5c5ef0b","type":"text","conversion_output":true,"text":"treatment.","text_display":" treatment.","confidence":1,"confidence_rate":1},{"cnt":[[245,1981],[1824,1981],[1824,2026],[245,2026]],"region":{"top_left_x":244,"top_left_y":1980,"width":1581,"height":46},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"03b6909fc1d8417aab4d944f1d04f405","type":"text","conversion_output":true,"text":"Our statistical analysis plan focuses on the effectiveness evaluation detailed under the Primary","text_display":"\n\nOur statistical analysis plan focuses on the effectiveness evaluation detailed under the Primary","confidence":1,"confidence_rate":1},{"cnt":[[245,2028],[1549,2028],[1549,2075],[245,2075]],"region":{"top_left_x":244,"top_left_y":2028,"width":1306,"height":48},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"150faad6358145fda6b9613f076c148b","type":"text","conversion_output":true,"text":"Objective in the protocol, We also provide a plan for mixed methods analyses","text_display":" Objective in the protocol, We also provide a plan for mixed methods analyses","confidence":1,"confidence_rate":1},{"cnt":[[247,2075],[1644,2075],[1644,2123],[247,2123]],"region":{"top_left_x":247,"top_left_y":2075,"width":1397,"height":48},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6d574051fc8d4f23afccd42faa07b8f7","type":"text","conversion_output":true,"text":"(qualitative/quantitative) associated with the Secondary Objective: implementation.","text_display":" (qualitative/quantitative) associated with the Secondary Objective: implementation.","confidence":0.9990234375,"confidence_rate":0.9999888973383643},{"cnt":[[245,2172],[1841,2172],[1841,2219],[245,2219]],"region":{"top_left_x":244,"top_left_y":2172,"width":1598,"height":48},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c789123506c4415c944b409061f3b525","type":"text","conversion_output":true,"text":"Primary Effectiveness Outcome \\# 1: prevention of cLBP that is impactful at \\(10-12\\) months follow-","text_display":"\n\nPrimary Effectiveness Outcome \\# 1: prevention of cLBP that is impactful at \\(10-12\\) months follow","confidence":0.5935921024065465,"confidence_rate":0.9949490816083003},{"cnt":[[245,2219],[1850,2219],[1850,2262],[245,2262]],"region":{"top_left_x":244,"top_left_y":2219,"width":1606,"height":44},"line":44,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bf2d0ec2d0b443708a8207355c537712","type":"text","conversion_output":true,"text":"up (LBP Impact scale ( \\(\\min 8\\) - max 50 ) using mean from months \\(10-12\\) ). The LBP impact scale includes","text_display":"up (LBP Impact scale ( \\(\\min 8\\) - max 50 ) using mean from months \\(10-12\\) ). The LBP impact scale includes","confidence":0.42682523783954013,"confidence_rate":0.9927496539883792},{"cnt":[[245,2262],[1878,2262],[1878,2305],[245,2305]],"region":{"top_left_x":244,"top_left_y":2262,"width":1634,"height":44},"line":45,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"56c236dc123e4198a2fcec2a64b223eb","type":"text","conversion_output":true,"text":"measures of pain intensity, pain interference, and physical function from the PROMIS-29 Profile v2.0) we","text_display":" measures of pain intensity, pain interference, and physical function from the PROMIS-29 Profile v2.0) we","confidence":0.99951171875,"confidence_rate":0.9999955192715237},{"cnt":[[245,2307],[1811,2307],[1811,2353],[245,2353]],"region":{"top_left_x":244,"top_left_y":2307,"width":1568,"height":46},"line":46,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9023fa79be5149a38455e14b51ea6f2c","type":"text","conversion_output":true,"text":"will determine the effectiveness of SMT, SSM, and the combination of SMT+SSM relative to","text_display":" will determine the effectiveness of SMT, SSM, and the combination of SMT+SSM relative to","confidence":1,"confidence_rate":1},{"cnt":[[245,2355],[569,2355],[569,2402],[245,2402]],"region":{"top_left_x":244,"top_left_y":2354,"width":326,"height":48},"line":47,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"61c21c8acdac4a72bf3dd8af279bf630","type":"text","conversion_output":true,"text":"medical care (MC)","text_display":" medical care (MC)","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1878,2582],[1878,2617],[1504,2617]],"region":{"top_left_x":1503,"top_left_y":2582,"width":375,"height":35},"line":48,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"0cb64077a8244dd790fc5d6ad7a9f724","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 59","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-60","page":60,"lines":[{"cnt":[[245,251],[1837,251],[1837,303],[245,303]],"region":{"top_left_x":244,"top_left_y":251,"width":1593,"height":52},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dd757cc8f2df49a8bfa83d58ab266403","type":"text","conversion_output":true,"text":"LBP Impact Effectiveness Hypothesis: SMT alone will decrease the impact of low back pain","text_display":"\n\nLBP Impact Effectiveness Hypothesis: SMT alone will decrease the impact of low back pain","confidence":1,"confidence_rate":1},{"cnt":[[245,301],[1863,301],[1863,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1619,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"12d014d86cfa481fae918b2ad12d38a6","type":"text","conversion_output":true,"text":"with at least a moderate effect size of 0.3 standard deviations (Cohen's d). Similarly, SSM alone","text_display":" with at least a moderate effect size of 0.3 standard deviations (Cohen's d). Similarly, SSM alone","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1794,348],[1794,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1550,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c25a6f369f9b438f818396660bb2050c","type":"text","conversion_output":true,"text":"will decrease the impact of low back pain with at least a moderate effect size of 0.3 standard","text_display":" will decrease the impact of low back pain with at least a moderate effect size of 0.3 standard","confidence":1,"confidence_rate":1},{"cnt":[[245,395],[1837,395],[1837,449],[245,449]],"region":{"top_left_x":244,"top_left_y":395,"width":1593,"height":55},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"16b34492ae7d4189aec75a71e93ecffe","type":"text","conversion_output":true,"text":"deviations. The combination SMT+SSM will lead to a stronger but not necessarily additive net","text_display":" deviations. The combination SMT+SSM will lead to a stronger but not necessarily additive net","confidence":1,"confidence_rate":1},{"cnt":[[245,443],[1302,443],[1302,494],[245,494]],"region":{"top_left_x":244,"top_left_y":442,"width":1058,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"04dd3af1403f4ef787582d9c1eab7b14","type":"text","conversion_output":true,"text":"reduction compared to the individual component interventions.","text_display":" reduction compared to the individual component interventions.","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1854,541],[1854,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1611,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4b5e59affd9743478e533ab0c3797837","type":"text","conversion_output":true,"text":"Design: As shown in Figure 9.1, we plan to enroll a total of 1000 subjects randomized to one of","text_display":"\n\nDesign: As shown in Figure 9.1, we plan to enroll a total of 1000 subjects randomized to one of","confidence":0.99169921875,"confidence_rate":0.9999190768222336},{"cnt":[[245,589],[1850,589],[1850,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1606,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4a339d8ca0084e6a9ff20c9c686ab1f6","type":"text","conversion_output":true,"text":"four treatment groups using a factorial design: medical care (MC); spinal manipulation therapy","text_display":" four treatment groups using a factorial design: medical care (MC); spinal manipulation therapy","confidence":0.9970715045928955,"confidence_rate":0.9999703762787923},{"cnt":[[245,636],[1644,636],[1644,690],[245,690]],"region":{"top_left_x":244,"top_left_y":635,"width":1400,"height":55},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6c0b364b6c7f4f0aa7222780d437d121","type":"text","conversion_output":true,"text":"alone (SMT); supported self-management alone (SSM); and combined SMT+SSM.","text_display":" alone (SMT); supported self-management alone (SSM); and combined SMT+SSM.","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1846,730],[1846,784],[245,784]],"region":{"top_left_x":244,"top_left_y":730,"width":1602,"height":55},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"84c858ba23694a4e9de9bd2bb90a4bca","type":"text","conversion_output":true,"text":"LBP Impact Primary Analysis: Our primary analysis will compare each of the treatment groups","text_display":"\n\nLBP Impact Primary Analysis: Our primary analysis will compare each of the treatment groups","confidence":1,"confidence_rate":1},{"cnt":[[245,780],[1833,780],[1833,831],[245,831]],"region":{"top_left_x":244,"top_left_y":779,"width":1589,"height":53},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"279bffcf22754531b11d238084f923a1","type":"text","conversion_output":true,"text":"to MC using an adjusted regression analysis. Specifically, Let \\(Y _{ ij }\\) denote the primary outcome","text_display":" to MC using an adjusted regression analysis. Specifically, Let \\(Y _{ ij }\\) denote the primary outcome","confidence":0.994140625,"confidence_rate":0.9999484521313653},{"cnt":[[245,829],[1841,829],[1841,879],[245,879]],"region":{"top_left_x":244,"top_left_y":829,"width":1598,"height":50},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9777c6456fd94f6cbad8b4488ecbfe77","type":"text","conversion_output":true,"text":"variable (average of LBP-Impact over months 10-12) for subject i in site j , and let \\(\\operatorname{Site}(2)\\) be an","text_display":" variable (average of LBP-Impact over months 10-12) for subject i in site j , and let \\(\\operatorname{Site}(2)\\) be an","confidence":0.8389164933151338,"confidence_rate":0.9985494488638237},{"cnt":[[245,872],[1858,872],[1858,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1615,"height":54},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"09e70feb491148d0921e2fe691cf31a3","type":"text","conversion_output":true,"text":"indicator variable used to code the two recruitment sites. All analyses will adjust for site and the","text_display":" indicator variable used to code the two recruitment sites. All analyses will adjust for site and the","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1867,924],[1867,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1623,"height":51},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"468ae4a46a034403bd7b682864b35664","type":"text","conversion_output":true,"text":"baseline risk status represented by RiskGroup ( \\(0=\\) medium risk; 1=high risk). In order to code the","text_display":" baseline risk status represented by RiskGroup ( \\(0=\\) medium risk; 1=high risk). In order to code the","confidence":0.6854402254823988,"confidence_rate":0.9964431897132852},{"cnt":[[245,971],[1818,971],[1818,1023],[245,1023]],"region":{"top_left_x":244,"top_left_y":971,"width":1574,"height":52},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7eacd352610c41f4b3ae1bbd453e7805","type":"text","conversion_output":true,"text":"treatment groups we use the variables SMT-Only ( \\(0=\\) no; \\(1=\\) only spinal manipulation therapy),","text_display":" treatment groups we use the variables SMT-Only ( \\(0=\\) no; \\(1=\\) only spinal manipulation therapy),","confidence":0.889409615575687,"confidence_rate":0.998873736733606},{"cnt":[[245,1018],[1858,1018],[1858,1070],[245,1070]],"region":{"top_left_x":244,"top_left_y":1018,"width":1615,"height":52},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"17717f3914564ae9b39bf29a6e751646","type":"text","conversion_output":true,"text":"SSM-Only ( \\(0=\\) no; \\(1=\\) only supported self-management), and SMT-and-SSM ( \\(0=\\) no, \\(1=\\) both SMT","text_display":" SSM-Only ( \\(0=\\) no; \\(1=\\) only supported self-management), and SMT-and-SSM ( \\(0=\\) no, \\(1=\\) both SMT","confidence":0.9849325515483542,"confidence_rate":0.9998581211336086},{"cnt":[[245,1066],[1635,1066],[1635,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1065,"width":1391,"height":55},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f08e547ddfee45c6bbea6474b52f46db","type":"text","conversion_output":true,"text":"and SSM). Given interruption by COVID-19 and an associated period of restricted","text_display":" and SSM). Given interruption by COVID-19 and an associated period of restricted","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1852,1113],[1852,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1608,"height":55},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"361f47df05a14da2813ea53945b3db35","type":"text","conversion_output":true,"text":"randomization we will also adjust for this modified randomization using the variables \\(\\operatorname{Period}(k)\\)","text_display":" randomization we will also adjust for this modified randomization using the variables \\(\\operatorname{Period}(k)\\)","confidence":0.7119140625,"confidence_rate":0.9966741891392386},{"cnt":[[245,1162],[1785,1162],[1785,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1542,"height":52},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"649888d9d96a4d46809122992077548f","type":"text","conversion_output":true,"text":"which will be an indicator for: 1=UG3 and UH3 through March 2020; 2=calendar period of","text_display":" which will be an indicator for: 1=UG3 and UH3 through March 2020; 2=calendar period of","confidence":0.47374677184416214,"confidence_rate":0.9918239115149693},{"cnt":[[245,1212],[1876,1212],[1876,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":1632,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ae007e74d94e4412893e1b4586bb1e68","type":"text","conversion_output":true,"text":"restricted randomization; and 3=calendar period of resumed full factorial randomization. We will","text_display":" restricted randomization; and 3=calendar period of resumed full factorial randomization. We will","confidence":0.900390625,"confidence_rate":0.9989616623960109},{"cnt":[[245,1259],[1833,1259],[1833,1311],[245,1311]],"region":{"top_left_x":244,"top_left_y":1258,"width":1589,"height":53},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1c3db60d69e146a6a756997f4d537235","type":"text","conversion_output":true,"text":"use an adjusted linear regression model with robust standard error to make inference regarding","text_display":" use an adjusted linear regression model with robust standard error to make inference regarding","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1790,1306],[1790,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1306,"width":1546,"height":54},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d031605fdb8346e2ae9f4e05baed6c14","type":"text","conversion_output":true,"text":"treatment groups using the following structure where \\(X_{i j}\\) denotes the covariates for subject i :","text_display":" treatment groups using the following structure where \\(X_{i j}\\) denotes the covariates for subject i :","confidence":0.8916015625,"confidence_rate":0.9990113861991761},{"cnt":[[236,1394],[1369,1394],[1369,1560],[236,1560]],"region":{"top_left_x":236,"top_left_y":1394,"width":1133,"height":166},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"be0c088c8a8349e8b2c7e9907fd24133","type":"math","conversion_output":true,"text":"\\[\n\\begin{aligned}\nE\\left(Y_{i j} \\mid\\right. & \\left.X_{i j}\\right)=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}-\\operatorname{Onl} y_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}-\\operatorname{Only} y_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{\\text {-and }-\\operatorname{SSM}_{i j}}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","text_display":"\n\\[\n\\begin{aligned}\nE\\left(Y_{i j} \\mid\\right. & \\left.X_{i j}\\right)=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}-\\operatorname{Onl} y_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}-\\operatorname{Only} y_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{\\text {-and }-\\operatorname{SSM}_{i j}}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","confidence":0.3109511608582542,"confidence_rate":0.9961138393488309},{"cnt":[[245,1594],[1293,1594],[1293,1648],[245,1648]],"region":{"top_left_x":244,"top_left_y":1594,"width":1050,"height":54},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a4811b6fc7314590b9201315eef9786b","type":"text","conversion_output":true,"text":"In the primary regression model the parameters of interest are:","text_display":"\n\nIn the primary regression model the parameters of interest are:","confidence":1,"confidence_rate":1},{"cnt":[[365,1646],[1422,1646],[1422,1697],[365,1697]],"region":{"top_left_x":365,"top_left_y":1645,"width":1058,"height":53},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"14e86183383e4e1f9a0b51159d29cb56","type":"text","conversion_output":true,"text":"\\(\\beta_{3}=\\) adjusted mean difference comparing SMT Only to UMC;","text_display":"\n\\(\\beta_{3}=\\) adjusted mean difference comparing SMT Only to UMC;","confidence":0.9951171875,"confidence_rate":0.9999258395321943},{"cnt":[[367,1693],[1420,1693],[1420,1747],[367,1747]],"region":{"top_left_x":367,"top_left_y":1692,"width":1054,"height":55},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6edbea8dcdc2423db01d0c85d97bf370","type":"text","conversion_output":true,"text":"\\(\\beta_{4}=\\) adjusted mean difference comparing SSM Only to UMC;","text_display":"\n\\(\\beta_{4}=\\) adjusted mean difference comparing SSM Only to UMC;","confidence":0.9990234375,"confidence_rate":0.9999851964785456},{"cnt":[[367,1745],[1669,1745],[1669,1794],[367,1794]],"region":{"top_left_x":367,"top_left_y":1744,"width":1303,"height":50},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"48f23edfb02147dd8afaa2af888a217f","type":"text","conversion_output":true,"text":"\\(\\beta_{5}=\\) adjusted mean difference comparing combined SMT and SSM to UMC.","text_display":"\n\\(\\beta_{5}=\\) adjusted mean difference comparing combined SMT and SSM to UMC.","confidence":0.99951171875,"confidence_rate":0.9999937384747559},{"cnt":[[245,1792],[1880,1792],[1880,1841],[245,1841]],"region":{"top_left_x":244,"top_left_y":1791,"width":1636,"height":51},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1bf3926865b0427b814f2f7ccbdfed7d","type":"text","conversion_output":true,"text":"Our primary analysis will test the global hypothesis that these three treatment comparisons are all","text_display":"\nOur primary analysis will test the global hypothesis that these three treatment comparisons are all","confidence":1,"confidence_rate":1},{"cnt":[[245,1839],[1783,1839],[1783,1893],[245,1893]],"region":{"top_left_x":244,"top_left_y":1839,"width":1540,"height":54},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f4b9afc28afc44798d659e088e6db911","type":"text","conversion_output":true,"text":"null using a multivariate Wald test with 3 degrees of freedom and alpha \\(=0.05\\). We will then","text_display":" null using a multivariate Wald test with 3 degrees of freedom and alpha \\(=0.05\\). We will then","confidence":0.9990234375,"confidence_rate":0.9999905142231668},{"cnt":[[245,1886],[1858,1886],[1858,1940],[245,1940]],"region":{"top_left_x":244,"top_left_y":1886,"width":1615,"height":55},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"26c1a1655a20466f86d285b3de92e17c","type":"text","conversion_output":true,"text":"provide individual confidence intervals for each coefficient that compares an intervention group","text_display":" provide individual confidence intervals for each coefficient that compares an intervention group","confidence":1,"confidence_rate":1},{"cnt":[[245,1934],[1833,1934],[1833,1987],[245,1987]],"region":{"top_left_x":244,"top_left_y":1933,"width":1589,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"46fce55696494c579a944e3f96d1672b","type":"text","conversion_output":true,"text":"to medical care based on Fishers least significant difference methods which provide individual","text_display":" to medical care based on Fishers least significant difference methods which provide individual","confidence":1,"confidence_rate":1},{"cnt":[[245,1983],[1794,1983],[1794,2035],[245,2035]],"region":{"top_left_x":244,"top_left_y":1983,"width":1550,"height":52},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f61e073b384046e1a393c2041356f0b7","type":"text","conversion_output":true,"text":"nominal \\(95 \\%\\) confidence intervals and also estimates the simultaneous coverage probability.","text_display":" nominal \\(95 \\%\\) confidence intervals and also estimates the simultaneous coverage probability.","confidence":0.9853515625,"confidence_rate":0.9998494318952309},{"cnt":[[245,2080],[1843,2080],[1843,2129],[245,2129]],"region":{"top_left_x":244,"top_left_y":2079,"width":1600,"height":51},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d7e7ba8cb1fe4551bcfccd4bbc93d135","type":"text","conversion_output":true,"text":"Power and Sample Size for Primary Outcome of LBP Impact: To characterize the power of our","text_display":"\n\nPower and Sample Size for Primary Outcome of LBP Impact: To characterize the power of our","confidence":1,"confidence_rate":1},{"cnt":[[245,2127],[1721,2127],[1721,2179],[245,2179]],"region":{"top_left_x":244,"top_left_y":2126,"width":1477,"height":53},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c7deef634f4a474eb8c9e257201fca48","type":"text","conversion_output":true,"text":"primary analysis (an overall F-test) we provide a summary table that considers potential","text_display":" primary analysis (an overall F-test) we provide a summary table that considers potential","confidence":1,"confidence_rate":1},{"cnt":[[245,2174],[1880,2174],[1880,2226],[245,2226]],"region":{"top_left_x":244,"top_left_y":2174,"width":1636,"height":52},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"843f14e970664e128997a4a45fbf36a0","type":"text","conversion_output":true,"text":"standardized mean differences comparing the individual intervention arms to medical care. For a","text_display":" standardized mean differences comparing the individual intervention arms to medical care. For a","confidence":1,"confidence_rate":1},{"cnt":[[245,2221],[1813,2221],[1813,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2221,"width":1570,"height":55},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bf592a5a73c54b909e39d4b996815dc8","type":"text","conversion_output":true,"text":"small effect size (Cohen's d of 0.2 ) and an additive effect we have greater than \\(90 \\%\\) power to","text_display":" small effect size (Cohen's d of 0.2 ) and an additive effect we have greater than \\(90 \\%\\) power to","confidence":0.9552399427630007,"confidence_rate":0.9995639739337432},{"cnt":[[245,2271],[1878,2271],[1878,2322],[245,2322]],"region":{"top_left_x":244,"top_left_y":2270,"width":1634,"height":53},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c6108c5724bd4f5b855dad8a74ccc1a8","type":"text","conversion_output":true,"text":"reject the null. However, additivity may not hold so we also consider sub-additive scenarios, and","text_display":" reject the null. However, additivity may not hold so we also consider sub-additive scenarios, and","confidence":1,"confidence_rate":1},{"cnt":[[245,2316],[1835,2316],[1835,2368],[245,2368]],"region":{"top_left_x":244,"top_left_y":2316,"width":1591,"height":52},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"32573073b0174867a65a10bbfd44fe7d","type":"text","conversion_output":true,"text":"the scenario where only one intervention is effective. For small to moderate effect sizes ( \\(0.2-\\)","text_display":" the scenario where only one intervention is effective. For small to moderate effect sizes ( \\(0.2-\\)","confidence":0.9799900054931641,"confidence_rate":0.9997978913682429},{"cnt":[[245,2363],[1843,2363],[1843,2417],[245,2417]],"region":{"top_left_x":244,"top_left_y":2363,"width":1600,"height":54},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4bc6214675bc40ff9a0e68fc22e0c1e3","type":"text","conversion_output":true,"text":"0.3 standard deviations) we have \\(>90 \\%\\) with our proposed design. We assume \\(n =1000\\) enrolled","text_display":" 0.3 standard deviations) we have \\(>90 \\%\\) with our proposed design. We assume \\(n =1000\\) enrolled","confidence":0.9804868698120117,"confidence_rate":0.9998068223400888},{"cnt":[[245,2415],[1749,2415],[1749,2464],[245,2464]],"region":{"top_left_x":244,"top_left_y":2414,"width":1505,"height":51},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6e0ae47bf1014a1eb43723053ab059b5","type":"text","conversion_output":true,"text":"with a realistic \\(90 \\%\\) follow-up that yields 900 evaluated subjects. We also account for the","text_display":" with a realistic \\(90 \\%\\) follow-up that yields 900 evaluated subjects. We also account for the","confidence":0.99951171875,"confidence_rate":0.9999951643631956},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"cffcaea8a7554572b3e5c16a4fb2ffe8","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 60","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-61","page":61,"lines":[{"cnt":[[245,254],[1850,254],[1850,303],[245,303]],"region":{"top_left_x":244,"top_left_y":253,"width":1606,"height":50},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"15a6eb431a48454ba72fc252116873de","type":"text","conversion_output":true,"text":"imbalanced design due to restricted randomization that will yield approximately 300 subjects in","text_display":"\nimbalanced design due to restricted randomization that will yield approximately 300 subjects in","confidence":1,"confidence_rate":1},{"cnt":[[245,301],[1828,301],[1828,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1585,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6ec6f5e9ffd8417d967e19349d7ea4c8","type":"text","conversion_output":true,"text":"the UMC and SSM alone groups and 200 subjects in each of the SMT and SMT+SSM groups.","text_display":" the UMC and SSM alone groups and 200 subjects in each of the SMT and SMT+SSM groups.","confidence":0.99951171875,"confidence_rate":0.9999946913130248},{"cnt":[[245,348],[1811,348],[1811,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1568,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"43a08f4186624ffdae2a5285a73bcab1","type":"text","conversion_output":true,"text":"Power is calculated based on 5,000 simulation replications for each scenario and presented in","text_display":" Power is calculated based on 5,000 simulation replications for each scenario and presented in","confidence":1,"confidence_rate":1},{"cnt":[[245,397],[423,397],[423,440],[245,440]],"region":{"top_left_x":244,"top_left_y":397,"width":180,"height":44},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e5f24a213e364a308e09608a706f87e1","type":"text","conversion_output":true,"text":"Table 9.1.","text_display":" Table 9.1.","confidence":1,"confidence_rate":1},{"cnt":[[245,494],[1833,494],[1833,544],[245,544]],"region":{"top_left_x":244,"top_left_y":494,"width":1589,"height":50},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6e83c708a92948f48662b055a60f0823","type":"text","conversion_output":true,"text":"The current design is robust to the enrollment target and follow-up assumptions. For example,","text_display":"\n\nThe current design is robust to the enrollment target and follow-up assumptions. For example,","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1824,541],[1824,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1581,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed8fc1db495f4c0b98dcd56aaccafc6a","type":"text","conversion_output":true,"text":"with an enrollment of \\(n =1000\\) subjects and \\(85 \\%\\) follow-up we would have \\(90 \\%\\) power for our","text_display":" with an enrollment of \\(n =1000\\) subjects and \\(85 \\%\\) follow-up we would have \\(90 \\%\\) power for our","confidence":0.9990234375,"confidence_rate":0.9999906054321309},{"cnt":[[245,589],[1824,589],[1824,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1581,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"25983eae01fe4b2ba4a988514848c8f9","type":"text","conversion_output":true,"text":"expected alternative scenario with small treatment effects ( 0.30 standardized mean difference)","text_display":" expected alternative scenario with small treatment effects ( 0.30 standardized mean difference)","confidence":0.9985356330871582,"confidence_rate":0.9999857725269791},{"cnt":[[245,636],[872,636],[872,690],[245,690]],"region":{"top_left_x":244,"top_left_y":635,"width":629,"height":55},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3aa001f3830d49568828ef7066a1f527","type":"text","conversion_output":true,"text":"that are not additive (sub-additive 1).","text_display":" that are not additive (sub-additive 1).","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1717,730],[1717,782],[245,782]],"region":{"top_left_x":244,"top_left_y":730,"width":1473,"height":53},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c2ccebf0db18430cb26e34d1f06b8d93","type":"text","conversion_output":true,"text":"A secondary evaluation will consider whether the separate effects of SMT and SSM are","text_display":"\n\nA secondary evaluation will consider whether the separate effects of SMT and SSM are","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1515,778],[1515,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":1271,"height":55},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"81558709439d4904be45c4ff82f35f38","type":"text","conversion_output":true,"text":"potentially additive and this will be done using a formal test for interaction:","text_display":" potentially additive and this will be done using a formal test for interaction:","confidence":0.99951171875,"confidence_rate":0.9999941857252588},{"cnt":[[243,872],[1545,872],[1545,930],[243,930]],"region":{"top_left_x":242,"top_left_y":872,"width":1303,"height":59},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"be577d67f28441a093060d1da4f34996","type":"text","conversion_output":true,"text":"Interaction Model: \\(\\quad E\\left(Y_{i j} \\mid X_{i j}\\right)=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+\\)","text_display":"\n\nInteraction Model: \\(\\quad E\\left(Y_{i j} \\mid X_{i j}\\right)=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+","confidence":0.9892864227294922,"confidence_rate":0.9999102425212293},{"cnt":[[868,924],[1635,924],[1635,978],[868,978]],"region":{"top_left_x":867,"top_left_y":923,"width":768,"height":55},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"81fadf6d70a84a348a962216dee48321","type":"text","conversion_output":true,"text":"\\(\\beta_{3} \\cdot S M T_{i j}+\\beta_{4} \\cdot S S M_{i j}+\\beta_{5} \\cdot S M T_{i j} \\cdot S S M_{i j}+\\)","text_display":" \\beta_{3} \\cdot S M T_{i j}+\\beta_{4} \\cdot S S M_{i j}+\\beta_{5} \\cdot S M T_{i j} \\cdot S S M_{i j}+","confidence":0.9887976534664631,"confidence_rate":0.9998626244930509},{"cnt":[[868,975],[1437,975],[1437,1027],[868,1027]],"region":{"top_left_x":867,"top_left_y":975,"width":571,"height":52},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7bac7b01e8504cc6a403fc1bc574f84f","type":"text","conversion_output":true,"text":"\\(\\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\\)","text_display":" \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\\)","confidence":0.9809746742248535,"confidence_rate":0.9996951474922959},{"cnt":[[242,1143],[1181,1143],[1181,1830],[242,1830]],"region":{"top_left_x":242,"top_left_y":1143,"width":939,"height":687},"line":14,"column":0,"font_size":31,"is_printed":true,"is_handwritten":false,"id":"422383fab46749ff86ff4ccc7030de6d","type":"column","conversion_output":false,"children_ids":["2b5b8f218b47482ba4f2960f83a4622c","26751f5a5df2465f8098a18c0db13f98"],"text":"","text_display":""},{"cnt":[[245,1145],[1177,1145],[1177,1274],[245,1274]],"region":{"top_left_x":244,"top_left_y":1145,"width":934,"height":130},"line":15,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2b5b8f218b47482ba4f2960f83a4622c","type":"figure_label","conversion_output":false,"parent_id":"422383fab46749ff86ff4ccc7030de6d","children_ids":["87511e878c44483290cd5f0b8d54b11a","eddb64566a184f91b7b59dafc2de0d0e","f5fa0352a489458ca3d67b3eb5fe78c8"],"text":"","text_display":""},{"cnt":[[254,1152],[1167,1152],[1167,1192],[254,1192]],"region":{"top_left_x":253,"top_left_y":1151,"width":914,"height":42},"line":16,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"87511e878c44483290cd5f0b8d54b11a","type":"text","conversion_output":false,"parent_id":"2b5b8f218b47482ba4f2960f83a4622c","text":"Table 9.1: Chronicity based on LBP-Impact averaged over months 10-","text_display":"","confidence":0.9643893241882324,"confidence_rate":0.9994894233092739},{"cnt":[[254,1190],[1171,1190],[1171,1231],[254,1231]],"region":{"top_left_x":253,"top_left_y":1190,"width":918,"height":42},"line":17,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"eddb64566a184f91b7b59dafc2de0d0e","type":"text","conversion_output":false,"parent_id":"2b5b8f218b47482ba4f2960f83a4622c","text":"12 of follow-up. Power for the overall F-test of equality of means under","text_display":"","confidence":0.99951171875,"confidence_rate":0.9999935736983052},{"cnt":[[254,1229],[831,1229],[831,1270],[254,1270]],"region":{"top_left_x":253,"top_left_y":1228,"width":579,"height":42},"line":18,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f5fa0352a489458ca3d67b3eb5fe78c8","type":"text","conversion_output":false,"parent_id":"2b5b8f218b47482ba4f2960f83a4622c","text":"various alternative scenarios. (alpha \\(=0.05\\) )","text_display":"","confidence":0.97705078125,"confidence_rate":0.9995620459001768},{"cnt":[[249,1261],[1177,1261],[1177,1826],[249,1826]],"region":{"top_left_x":249,"top_left_y":1261,"width":929,"height":566},"line":19,"column":1,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"26751f5a5df2465f8098a18c0db13f98","type":"table","conversion_output":true,"parent_id":"422383fab46749ff86ff4ccc7030de6d","selected_labels":["2b5b8f218b47482ba4f2960f83a4622c"],"text":"\\begin{tabular}{|l|l|l|l|l|}\n\\hline Alternative & \\begin{tabular}{l} \nSMT \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSSM \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSMT \\\\\n\\(+\\) \\\\\nSSM\n\\end{tabular} & Power \\\\\n\\hline Additive & 0.20 & 0.20 & 0.40 & \\(9 3 \\%\\) \\\\\n\\hline Sub-Additive 1 & 0.25 & 0.25 & 0.35 & \\(9 1 \\%\\) \\\\\n\\hline Sub-Additive 2 & 0.30 & 0.30 & 0.30 & \\(9 4 \\%\\) \\\\\n\\hline Sub-Additive 3 & 0.25 & 0.25 & 0.25 & \\(8 1 \\%\\) \\\\\n\\hline Single effect 1a & 0 & 0.30 & 0.30 & \\(9 8 \\%\\) \\\\\n\\hline Single effect 1 \\(b\\) & 0.30 & 0 & 0.30 & \\(9 4 \\%\\) \\\\\n\\hline Single effect 2a & 0 & 0.25 & 0.25 & \\(9 1 \\%\\) \\\\\n\\hline Single effect 2b & 0.25 & 0 & 0.25 & \\(8 0 \\%\\) \\\\\n\\hline\n\\end{tabular}","text_display":"\n\n\\begin{table}\n\\captionsetup{labelformat=empty}\n\\caption{Table 9.1: Chronicity based on LBP-Impact averaged over months 1012 of follow-up. Power for the overall F-test of equality of means under various alternative scenarios. (alpha \\(=0.05\\) )}\n\\begin{tabular}{|l|l|l|l|l|}\n\\hline Alternative & \\begin{tabular}{l} \nSMT \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSSM \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSMT \\\\\n\\(+\\) \\\\\nSSM\n\\end{tabular} & Power \\\\\n\\hline Additive & 0.20 & 0.20 & 0.40 & \\(9 3 \\%\\) \\\\\n\\hline Sub-Additive 1 & 0.25 & 0.25 & 0.35 & \\(9 1 \\%\\) \\\\\n\\hline Sub-Additive 2 & 0.30 & 0.30 & 0.30 & \\(9 4 \\%\\) \\\\\n\\hline Sub-Additive 3 & 0.25 & 0.25 & 0.25 & \\(8 1 \\%\\) \\\\\n\\hline Single effect 1a & 0 & 0.30 & 0.30 & \\(9 8 \\%\\) \\\\\n\\hline Single effect 1 \\(b\\) & 0.30 & 0 & 0.30 & \\(9 4 \\%\\) \\\\\n\\hline Single effect 2a & 0 & 0.25 & 0.25 & \\(9 1 \\%\\) \\\\\n\\hline Single effect 2b & 0.25 & 0 & 0.25 & \\(8 0 \\%\\) \\\\\n\\hline\n\\end{tabular}\n\\end{table}","confidence":0.6731685367622616,"confidence_rate":0.9992972993107521},{"cnt":[[1225,1113],[1772,1113],[1772,1171],[1225,1171]],"region":{"top_left_x":1224,"top_left_y":1112,"width":549,"height":59},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1da90499d8d74c2095d4867bfedc6de1","type":"text","conversion_output":true,"text":"In this model a test of H 0 : \\(\\beta 5=0\\)","text_display":"\n\nIn this model a test of H 0 : \\(\\beta 5=0\\)","confidence":0.9980475902557373,"confidence_rate":0.9999545517727879},{"cnt":[[1225,1164],[1781,1164],[1781,1214],[1225,1214]],"region":{"top_left_x":1224,"top_left_y":1164,"width":558,"height":50},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5d7027df822c47559cc6f4e3a1c497f9","type":"text","conversion_output":true,"text":"allows us to determine if there is","text_display":" allows us to determine if there is","confidence":1,"confidence_rate":1},{"cnt":[[1225,1214],[1798,1214],[1798,1265],[1225,1265]],"region":{"top_left_x":1224,"top_left_y":1213,"width":575,"height":53},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5a9afaa84aa8446e91a10f8d3ca4b24a","type":"text","conversion_output":true,"text":"strong evidence for synergistic or","text_display":" strong evidence for synergistic or","confidence":1,"confidence_rate":1},{"cnt":[[1225,1263],[1828,1263],[1828,1313],[1225,1313]],"region":{"top_left_x":1224,"top_left_y":1263,"width":605,"height":50},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9567563f87704685ac692718ad6a7cda","type":"text","conversion_output":true,"text":"antagonistic effects associated with","text_display":" antagonistic effects associated with","confidence":1,"confidence_rate":1},{"cnt":[[1225,1311],[1579,1311],[1579,1360],[1225,1360]],"region":{"top_left_x":1224,"top_left_y":1310,"width":356,"height":50},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2098b21e72374dd0af48e7c9b40fc5e9","type":"text","conversion_output":true,"text":"combined treatment.","text_display":" combined treatment.","confidence":1,"confidence_rate":1},{"cnt":[[1225,1405],[1841,1405],[1841,1454],[1225,1454]],"region":{"top_left_x":1224,"top_left_y":1405,"width":618,"height":50},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ceca79d643d34bdf81aeb30e2ba75330","type":"text","conversion_output":true,"text":"Secondary Effectiveness Outcome","text_display":"\n\nSecondary Effectiveness Outcome","confidence":1,"confidence_rate":1},{"cnt":[[1225,1452],[1813,1452],[1813,1506],[1225,1506]],"region":{"top_left_x":1224,"top_left_y":1452,"width":590,"height":55},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"aa7a9a6a39574ab196e7b083bd68c444","type":"text","conversion_output":true,"text":"of Chronicity: Chronic back pain:","text_display":" of Chronicity: Chronic back pain:","confidence":1,"confidence_rate":1},{"cnt":[[1225,1502],[1790,1502],[1790,1553],[1225,1553]],"region":{"top_left_x":1224,"top_left_y":1501,"width":566,"height":53},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b22ffd4b7f49434bb5d0f1a898bb8c94","type":"text","conversion_output":true,"text":"For a subject to be classified as a","text_display":" For a subject to be classified as a","confidence":1,"confidence_rate":1},{"cnt":[[1225,1547],[1880,1547],[1880,1601],[1225,1601]],"region":{"top_left_x":1224,"top_left_y":1546,"width":656,"height":55},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"444a34bb547f43ab9978352a6027e2cb","type":"text","conversion_output":true,"text":"chronic back pain patient at the 1-year","text_display":" chronic back pain patient at the 1-year","confidence":0.6259765625,"confidence_rate":0.9894100554945648},{"cnt":[[1225,1598],[1863,1598],[1863,1652],[1225,1652]],"region":{"top_left_x":1224,"top_left_y":1598,"width":639,"height":55},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"01f29ec7a28c40a780f4991c2e7e48ed","type":"text","conversion_output":true,"text":"assessment they must endorse having","text_display":" assessment they must endorse having","confidence":1,"confidence_rate":1},{"cnt":[[1225,1646],[1734,1646],[1734,1695],[1225,1695]],"region":{"top_left_x":1224,"top_left_y":1645,"width":510,"height":51},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"db94b7de46944c97a26c6fa4b693142b","type":"text","conversion_output":true,"text":"\"a back pain problem that has","text_display":" \"a back pain problem that has","confidence":1,"confidence_rate":1},{"cnt":[[1225,1693],[1815,1693],[1815,1745],[1225,1745]],"region":{"top_left_x":1224,"top_left_y":1692,"width":592,"height":53},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"893b4c359690438caaa3a0dc0b33a705","type":"text","conversion_output":true,"text":"persisted at least 3 months and has","text_display":" persisted at least 3 months and has","confidence":1,"confidence_rate":1},{"cnt":[[1225,1740],[1858,1740],[1858,1790],[1225,1790]],"region":{"top_left_x":1224,"top_left_y":1740,"width":635,"height":50},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f75a042dad384127a63cd2659bd8799c","type":"text","conversion_output":true,"text":"resulted in pain on at least half of the","text_display":" resulted in pain on at least half of the","confidence":1,"confidence_rate":1},{"cnt":[[1225,1788],[1775,1788],[1775,1841],[1225,1841]],"region":{"top_left_x":1224,"top_left_y":1787,"width":551,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"acf92e8c3e5b4874a02adaeef84038cd","type":"text","conversion_output":true,"text":"days in the past 6 months\". This","text_display":" days in the past 6 months\". This","confidence":1,"confidence_rate":1},{"cnt":[[1225,1835],[1815,1835],[1815,1886],[1225,1886]],"region":{"top_left_x":1224,"top_left_y":1834,"width":592,"height":53},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"43d32612df5040cea4fe925430b5a457","type":"text","conversion_output":true,"text":"outcome is based on specific items","text_display":" outcome is based on specific items","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1747,1882],[1747,1936],[245,1936]],"region":{"top_left_x":244,"top_left_y":1882,"width":1503,"height":54},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b4f19ff596874359a049ea26f909740d","type":"text","conversion_output":true,"text":"from the NIH Research Task Force recommended minimal data set: \\({ }^{73}\\) Question 1 on LBP","text_display":" from the NIH Research Task Force recommended minimal data set: \\({ }^{73}\\) Question 1 on LBP","confidence":1,"confidence_rate":1},{"cnt":[[245,1931],[1807,1931],[1807,1983],[245,1983]],"region":{"top_left_x":244,"top_left_y":1931,"width":1563,"height":53},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"74c62241f83943d39588f23156a85606","type":"text","conversion_output":true,"text":"duration; and Question 2 on the proportion of days that LBP has been a problem in the past 6","text_display":" duration; and Question 2 on the proportion of days that LBP has been a problem in the past 6","confidence":0.994140625,"confidence_rate":0.9999406420800441},{"cnt":[[245,1981],[1796,1981],[1796,2032],[245,2032]],"region":{"top_left_x":244,"top_left_y":1980,"width":1553,"height":53},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a3604c0f5ec24f2f80526006e9ea16cd","type":"text","conversion_output":true,"text":"months. To evaluate chronic back pain we will consider the 1 -year status as a key secondary","text_display":" months. To evaluate chronic back pain we will consider the 1 -year status as a key secondary","confidence":1,"confidence_rate":1},{"cnt":[[245,2028],[1798,2028],[1798,2082],[245,2082]],"region":{"top_left_x":244,"top_left_y":2028,"width":1555,"height":54},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4f550bed0193452f9370146a23b6f0d9","type":"text","conversion_output":true,"text":"outcome for chronicity prevention, and will use the 6-month status as another key secondary","text_display":" outcome for chronicity prevention, and will use the 6-month status as another key secondary","confidence":0.50390625,"confidence_rate":0.9928862045195326},{"cnt":[[245,2080],[408,2080],[408,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2079,"width":165,"height":46},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5041ef92c98a47bca46281d383ed8e94","type":"text","conversion_output":true,"text":"outcome.","text_display":" outcome.","confidence":1,"confidence_rate":1},{"cnt":[[245,2170],[1811,2170],[1811,2224],[245,2224]],"region":{"top_left_x":244,"top_left_y":2169,"width":1568,"height":55},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"083d4ecce6894acbb122c9f2af548d19","type":"text","conversion_output":true,"text":"Chronicity Hypothesis: SMT alone will decrease the rate of cLBP by \\(6-9 \\%\\) from a baseline","text_display":"\n\nChronicity Hypothesis: SMT alone will decrease the rate of cLBP by \\(6-9 \\%\\) from a baseline","confidence":0.99951171875,"confidence_rate":0.9999948589553403},{"cnt":[[245,2219],[1841,2219],[1841,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2219,"width":1598,"height":52},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"20af4b03772e40ebbebd774fc5948342","type":"text","conversion_output":true,"text":"MC level anticipated to be \\(20 \\%\\) or higher. Similarly, SSM alone will decrease the rate of cLBP","text_display":" MC level anticipated to be \\(20 \\%\\) or higher. Similarly, SSM alone will decrease the rate of cLBP","confidence":1,"confidence_rate":1},{"cnt":[[245,2269],[1637,2269],[1637,2322],[245,2322]],"region":{"top_left_x":244,"top_left_y":2268,"width":1394,"height":55},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4d97123b3792463289282a075f44f4a1","type":"text","conversion_output":true,"text":"by \\(6-9 \\%\\), and the combination of SMT+SSM will lead to an additive net reduction.","text_display":" by \\(6-9 \\%\\), and the combination of SMT+SSM will lead to an additive net reduction.","confidence":1,"confidence_rate":1},{"cnt":[[245,2363],[1858,2363],[1858,2417],[245,2417]],"region":{"top_left_x":244,"top_left_y":2363,"width":1615,"height":54},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f05d54cd1f2543b5b2424471cbe14b61","type":"text","conversion_output":true,"text":"Secondary Chronicity outcome Analysis: The analysis of the secondary binary outcome will use","text_display":"\n\nSecondary Chronicity outcome Analysis: The analysis of the secondary binary outcome will use","confidence":1,"confidence_rate":1},{"cnt":[[245,2413],[1843,2413],[1843,2464],[245,2464]],"region":{"top_left_x":244,"top_left_y":2412,"width":1600,"height":53},"line":44,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6ef16bb2481c47e9901b161be649c96e","type":"text","conversion_output":true,"text":"parallel marginalized tests of the average SMT treatment effect and the average SSM treatment","text_display":" parallel marginalized tests of the average SMT treatment effect and the average SSM treatment","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":45,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"3c7928657629447785d44930eb3454ff","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 61","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-62","page":62,"lines":[{"cnt":[[245,254],[1766,254],[1766,303],[245,303]],"region":{"top_left_x":244,"top_left_y":253,"width":1523,"height":50},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b8a8f2bb29e442648ac4c0051dc7812d","type":"text","conversion_output":true,"text":"effect using linear contrasts from a logistic regression model. Specifically, we will use two","text_display":"\neffect using linear contrasts from a logistic regression model. Specifically, we will use two","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[245,301],[1760,301],[1760,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1516,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"837334bc45f64e36bf313f9c14630201","type":"text","conversion_output":true,"text":"separate Wald tests based on logistic regression, with stratification by recruitment site and","text_display":" separate Wald tests based on logistic regression, with stratification by recruitment site and","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1826,348],[1826,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1583,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ee0a8ee42a2a4b8ca2fe565937af5936","type":"text","conversion_output":true,"text":"baseline risk group (medium, high). Let \\(Y _{ ij }\\) denote the primary outcome status \\((0=\\) not chronic;","text_display":" baseline risk group (medium, high). Let \\(Y _{ ij }\\) denote the primary outcome status \\((0=\\) not chronic;","confidence":0.7942450046539307,"confidence_rate":0.9980496730485082},{"cnt":[[247,397],[1790,397],[1790,445],[247,445]],"region":{"top_left_x":247,"top_left_y":397,"width":1543,"height":48},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"364435216b414668ad16d9327350decc","type":"text","conversion_output":true,"text":"1=chronic) for subject i in site j, and let \\(\\operatorname{Site}(2)\\) be an indicator variable used to code the two","text_display":" 1=chronic) for subject i in site j, and let \\(\\operatorname{Site}(2)\\) be an indicator variable used to code the two","confidence":0.3343886551891484,"confidence_rate":0.9899081996127927},{"cnt":[[245,443],[1781,443],[1781,494],[245,494]],"region":{"top_left_x":244,"top_left_y":442,"width":1538,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5f691f4a3d264d98959152d2c2b9f4cf","type":"text","conversion_output":true,"text":"recruitment sites. All analyses will adjust for site and the baseline risk status represented by","text_display":" recruitment sites. All analyses will adjust for site and the baseline risk status represented by","confidence":1,"confidence_rate":1},{"cnt":[[245,492],[1768,492],[1768,544],[245,544]],"region":{"top_left_x":244,"top_left_y":491,"width":1525,"height":53},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f5eec32e44c34162a869d7ee3bc53ff5","type":"text","conversion_output":true,"text":"RiskGroup ( \\(0=\\) medium risk; 1=high risk). In order to code the treatment groups we use the","text_display":" RiskGroup ( \\(0=\\) medium risk; 1=high risk). In order to code the treatment groups we use the","confidence":0.6880282173063673,"confidence_rate":0.9961917044255114},{"cnt":[[245,541],[1742,541],[1742,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1499,"height":50},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4058047bea6f4aee9544f52d631e9ca3","type":"text","conversion_output":true,"text":"variables \\(\\operatorname{SMT}(0=\\) no; \\(1=\\) spinal manipulation therapy), and \\(\\operatorname{SSM}(0=\\) no; \\(1=\\) supported self-","text_display":" variables \\(\\operatorname{SMT}(0=\\) no; \\(1=\\) spinal manipulation therapy), and \\(\\operatorname{SSM}(0=\\) no; \\(1=\\) supported self","confidence":0.9844606313421336,"confidence_rate":0.9998576340424329},{"cnt":[[245,589],[1846,589],[1846,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1602,"height":51},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e166fe91055d497a85a43d3cb3d2f429","type":"text","conversion_output":true,"text":"management). Given interruption by COVID-19 and period of restricted randomization we will","text_display":"management). Given interruption by COVID-19 and period of restricted randomization we will","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1790,636],[1790,685],[245,685]],"region":{"top_left_x":244,"top_left_y":635,"width":1546,"height":51},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7e11d83b356f4ff9af2d0cd758c75985","type":"text","conversion_output":true,"text":"adjust for this using the variables Period \\((k)\\) which will be an indicator for: \\(1= UG 3\\) and UH3","text_display":" adjust for this using the variables Period \\((k)\\) which will be an indicator for: \\(1= UG 3\\) and UH3","confidence":0.7723873296491357,"confidence_rate":0.9975664646105243},{"cnt":[[245,683],[1828,683],[1828,735],[245,735]],"region":{"top_left_x":244,"top_left_y":683,"width":1585,"height":52},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed4855ba723b47feb300170e5a651b52","type":"text","conversion_output":true,"text":"through March 2020; 2=calendar period of restricted randomization; and 3=calendar period of","text_display":" through March 2020; 2=calendar period of restricted randomization; and 3=calendar period of","confidence":0.9185357093811035,"confidence_rate":0.9991152406186178},{"cnt":[[245,730],[1824,730],[1824,780],[245,780]],"region":{"top_left_x":244,"top_left_y":730,"width":1581,"height":50},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1f4bf6d1ec044457a42fb1079ed61ab8","type":"text","conversion_output":true,"text":"resumed full factorial randomization. Regression models for the outcome are used to structure","text_display":" resumed full factorial randomization. Regression models for the outcome are used to structure","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1042,778],[1042,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":798,"height":55},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5ffdf5ff97cb4a4bb0ab9dacc4bbe95c","type":"text","conversion_output":true,"text":"the probability of chronic back pain as follows:","text_display":" the probability of chronic back pain as follows:","confidence":1,"confidence_rate":1},{"cnt":[[262,872],[531,872],[531,922],[262,922]],"region":{"top_left_x":262,"top_left_y":872,"width":269,"height":50},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"29f74d4a3b1e4168b5bc732a028fb178","type":"text","conversion_output":true,"text":"Additive Model","text_display":"\n\nAdditive Model","confidence":1,"confidence_rate":1},{"cnt":[[621,870],[1665,870],[1665,1033],[621,1033]],"region":{"top_left_x":620,"top_left_y":870,"width":1046,"height":164},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"34d5823c78f94161ac8bffcaab89e293","type":"math","conversion_output":true,"text":"\\[\n\\begin{gathered}\n\\operatorname{logit}\\left[P\\left(Y_{i j}=1 \\mid X_{i j}\\right)\\right]=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n\\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+ \\\\\n\\beta_{5} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{6} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{gathered}\n\\]","text_display":"\n\\[\n\\begin{gathered}\n\\operatorname{logit}\\left[P\\left(Y_{i j}=1 \\mid X_{i j}\\right)\\right]=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n\\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+ \\\\\n\\beta_{5} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{6} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{gathered}\n\\]","confidence":0.6601948620431337,"confidence_rate":0.9982927337640881},{"cnt":[[262,1070],[466,1070],[466,1119],[262,1119]],"region":{"top_left_x":262,"top_left_y":1069,"width":205,"height":51},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"56cdc4cfb81d472e94b5f225ffa5ce90","type":"text","conversion_output":true,"text":"Full Model","text_display":"\n\nFull Model","confidence":1,"confidence_rate":1},{"cnt":[[612,1066],[1592,1066],[1592,1229],[612,1229]],"region":{"top_left_x":612,"top_left_y":1065,"width":980,"height":164},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"86c741d981a340f0a5a880ae29e569bd","type":"math","conversion_output":true,"text":"\\[\n\\begin{gathered}\n\\operatorname{logit}[P(Y i j=1)]=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n\\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+\\beta_{5} \\cdot \\operatorname{SSM}_{i j} \\cdot \\operatorname{SMT}_{i j}+ \\\\\n\\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{gathered}\n\\]","text_display":"\n\\[\n\\begin{gathered}\n\\operatorname{logit}[P(Y i j=1)]=\\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n\\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+\\beta_{5} \\cdot \\operatorname{SSM}_{i j} \\cdot \\operatorname{SMT}_{i j}+ \\\\\n\\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{gathered}\n\\]","confidence":0.9354424147370675,"confidence_rate":0.9997433572046991},{"cnt":[[245,1311],[1727,1311],[1727,1364],[245,1364]],"region":{"top_left_x":244,"top_left_y":1310,"width":1484,"height":55},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d2604dca606e4fb786b4c33825cbb03f","type":"text","conversion_output":true,"text":"Our original application proposed using an additive model to generate a single summary","text_display":"\n\nOur original application proposed using an additive model to generate a single summary","confidence":1,"confidence_rate":1},{"cnt":[[245,1360],[1876,1360],[1876,1412],[245,1412]],"region":{"top_left_x":244,"top_left_y":1359,"width":1632,"height":53},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dea85583a1ef42c1ad9175026de4d048","type":"text","conversion_output":true,"text":"parameter that describes the SMT effect ( \\(\\beta 3\\) ) and the independent SSM effect ( \\(\\beta 4\\) ). However, the","text_display":" parameter that describes the SMT effect ( \\(\\beta 3\\) ) and the independent SSM effect ( \\(\\beta 4\\) ). However, the","confidence":0.9922089320737632,"confidence_rate":0.9999282449886051},{"cnt":[[245,1405],[1850,1405],[1850,1459],[245,1459]],"region":{"top_left_x":244,"top_left_y":1405,"width":1606,"height":54},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f2df3f1ec1ad4c6aa202e8c9a1d64e5b","type":"text","conversion_output":true,"text":"additive model uses an assumption that the effect of one intervention is independent of whether","text_display":" additive model uses an assumption that the effect of one intervention is independent of whether","confidence":1,"confidence_rate":1},{"cnt":[[245,1454],[1858,1454],[1858,1506],[245,1506]],"region":{"top_left_x":244,"top_left_y":1454,"width":1615,"height":53},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"fd8dea41ec1e43e8a96a6a3e17437fd8","type":"text","conversion_output":true,"text":"the other intervention is delivered. Such an assumption is not necessary, and a full model can be","text_display":" the other intervention is delivered. Such an assumption is not necessary, and a full model can be","confidence":1,"confidence_rate":1},{"cnt":[[245,1504],[1837,1504],[1837,1555],[245,1555]],"region":{"top_left_x":244,"top_left_y":1503,"width":1593,"height":53},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c121ac48a1b84648baf027c3caac8dc5","type":"text","conversion_output":true,"text":"used to make inference on a single linear contrast for each treatment that represents an average","text_display":" used to make inference on a single linear contrast for each treatment that represents an average","confidence":1,"confidence_rate":1},{"cnt":[[245,1551],[526,1551],[526,1601],[245,1601]],"region":{"top_left_x":244,"top_left_y":1551,"width":283,"height":50},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"feb18a3b889445e6875315c400734b09","type":"text","conversion_output":true,"text":"treatment effect.","text_display":" treatment effect.","confidence":1,"confidence_rate":1},{"cnt":[[245,1646],[1863,1646],[1863,1697],[245,1697]],"region":{"top_left_x":244,"top_left_y":1645,"width":1619,"height":53},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b52f479c75d04fa1aa705728027d6fb8","type":"text","conversion_output":true,"text":"The \"Full Model\" can then be used to derive an overall or average effect of SMT, and an overall","text_display":"\n\nThe \"Full Model\" can then be used to derive an overall or average effect of SMT, and an overall","confidence":1,"confidence_rate":1},{"cnt":[[245,1693],[1714,1693],[1714,1747],[245,1747]],"region":{"top_left_x":244,"top_left_y":1692,"width":1471,"height":55},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ec9c49b56a284a2593dac10dd9f420db","type":"text","conversion_output":true,"text":"or average effect of SSM. Specifically, focusing on the effect of SMT the model yields:","text_display":" or average effect of SSM. Specifically, focusing on the effect of SMT the model yields:","confidence":1,"confidence_rate":1},{"cnt":[[363,1788],[1545,1788],[1545,1962],[363,1962]],"region":{"top_left_x":363,"top_left_y":1787,"width":1182,"height":175},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"59e7f2564fa14f83a6864cb63b6d1ab2","type":"table","conversion_output":true,"text":"\\begin{tabular}{ll} \nSMT effect when SSM \\(=0:\\) & \\(\\beta 3\\) \\\\\nSMT effect when SSM \\(=1:\\) & \\(\\beta 3+\\beta 5\\) \\\\\nAverage SMT effect: & \\(1 / 2 \\beta 3+1 / 2(\\beta 3+\\beta 5)=\\beta 3+1 / 2 \\beta 5\\)\n\\end{tabular}","text_display":"\n\n\\begin{tabular}{ll} \nSMT effect when SSM \\(=0:\\) & \\(\\beta 3\\) \\\\\nSMT effect when SSM \\(=1:\\) & \\(\\beta 3+\\beta 5\\) \\\\\nAverage SMT effect: & \\(1 / 2 \\beta 3+1 / 2(\\beta 3+\\beta 5)=\\beta 3+1 / 2 \\beta 5\\)\n\\end{tabular}","confidence":0.8863408296601847,"confidence_rate":0.999093240537307},{"cnt":[[245,1981],[1848,1981],[1848,2035],[245,2035]],"region":{"top_left_x":244,"top_left_y":1980,"width":1604,"height":55},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e74d0a4771254a868ee4f7c35e6c52e2","type":"text","conversion_output":true,"text":"Our original analysis plan used an additive regression model that did not include the interaction","text_display":"\n\nOur original analysis plan used an additive regression model that did not include the interaction","confidence":1,"confidence_rate":1},{"cnt":[[245,2032],[1850,2032],[1850,2082],[245,2082]],"region":{"top_left_x":244,"top_left_y":2032,"width":1606,"height":50},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f1befabbb67d4d2093f25f34d6780116","type":"text","conversion_output":true,"text":"term in order to generate a model-based average effect of SMT. By using the full model, we are","text_display":" term in order to generate a model-based average effect of SMT. By using the full model, we are","confidence":1,"confidence_rate":1},{"cnt":[[245,2080],[1824,2080],[1824,2133],[245,2133]],"region":{"top_left_x":244,"top_left_y":2079,"width":1581,"height":55},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ba0035685caf4debab4a8a7f079123eb","type":"text","conversion_output":true,"text":"not making any assumption of constancy of SMT effect across the two strata defined by SSM,","text_display":" not making any assumption of constancy of SMT effect across the two strata defined by SSM,","confidence":1,"confidence_rate":1},{"cnt":[[245,2127],[1880,2127],[1880,2179],[245,2179]],"region":{"top_left_x":244,"top_left_y":2126,"width":1636,"height":53},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"765fe25d88114d48b00bbec3cc051e23","type":"text","conversion_output":true,"text":"and are directly calculating the average of the two treatment effects as the linear contrast that will","text_display":" and are directly calculating the average of the two treatment effects as the linear contrast that will","confidence":1,"confidence_rate":1},{"cnt":[[245,2174],[1803,2174],[1803,2228],[245,2228]],"region":{"top_left_x":244,"top_left_y":2174,"width":1559,"height":54},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c3a7ac42db3f4fdbaa60c7a11003544e","type":"text","conversion_output":true,"text":"be used to summarize the overall effect of SMT. The model can similarly be used to derive a","text_display":" be used to summarize the overall effect of SMT. The model can similarly be used to derive a","confidence":1,"confidence_rate":1},{"cnt":[[245,2221],[1143,2221],[1143,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2221,"width":899,"height":55},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8fa4143f6ac94c188356ff2640e707d3","type":"text","conversion_output":true,"text":"linear contrast the represents the average SSM effect:","text_display":" linear contrast the represents the average SSM effect:","confidence":1,"confidence_rate":1},{"cnt":[[363,2314],[1549,2314],[1549,2471],[363,2471]],"region":{"top_left_x":363,"top_left_y":2313,"width":1187,"height":158},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"10c1e054c74e4e88841558945c492f4d","type":"table","conversion_output":true,"text":"\\begin{tabular}{ll} \nSSM effect when SMT \\(=0:\\) & \\(\\beta 4\\) \\\\\nSSM effect when SMT \\(=1:\\) & \\(\\beta 4+\\beta 5\\) \\\\\nAverage SSM effect: & \\(1 / 2 \\beta 4+1 / 2(\\beta 4+\\beta 5)=\\beta 4+1 / 2 \\beta 5\\)\n\\end{tabular}","text_display":"\n\n\\begin{tabular}{ll} \nSSM effect when SMT \\(=0:\\) & \\(\\beta 4\\) \\\\\nSSM effect when SMT \\(=1:\\) & \\(\\beta 4+\\beta 5\\) \\\\\nAverage SSM effect: & \\(1 / 2 \\beta 4+1 / 2(\\beta 4+\\beta 5)=\\beta 4+1 / 2 \\beta 5\\)\n\\end{tabular}","confidence":0.9965834617614746,"confidence_rate":0.9999742680909742},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":39,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"5533e7a1fe5e4b0c8bceb9ebcbd9a743","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 62","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-63","page":63,"lines":[{"cnt":[[245,301],[1751,301],[1751,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1507,"height":51},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f6c4f70fe12e4e8d90ee3e1600d66d99","type":"text","conversion_output":true,"text":"The overall SMT summary ( \\(\\beta 3+1 / 2 \\beta 5\\) ) estimates a common or average effect of SMT by","text_display":"\n\nThe overall SMT summary ( \\(\\beta 3+1 / 2 \\beta 5\\) ) estimates a common or average effect of SMT by","confidence":0.4950774771621893,"confidence_rate":0.9923040413352984},{"cnt":[[245,348],[1867,348],[1867,400],[245,400]],"region":{"top_left_x":244,"top_left_y":348,"width":1623,"height":52},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dfc72f08decc41dab02b005e10e620ab","type":"text","conversion_output":true,"text":"pooling across sites, across risk groups, and across the two SSM arms (see figure 9.2). Similarly,","text_display":" pooling across sites, across risk groups, and across the two SSM arms (see figure 9.2). Similarly,","confidence":1,"confidence_rate":1},{"cnt":[[245,397],[1809,397],[1809,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":1565,"height":53},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"45baec679caa4ec09e51971b64868931","type":"text","conversion_output":true,"text":"\\(\\beta 4+1 / 2 \\beta 5\\) estimates a common or average effect of SSM by pooling over the site, risk group,","text_display":" \\(\\beta 4+1 / 2 \\beta 5\\) estimates a common or average effect of SSM by pooling over the site, risk group,","confidence":0.9970703125,"confidence_rate":0.9999687878548241},{"cnt":[[245,447],[1878,447],[1878,496],[245,496]],"region":{"top_left_x":244,"top_left_y":446,"width":1634,"height":51},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"76c532b7269846c3b1ca1ddc66789240","type":"text","conversion_output":true,"text":"and SMT strata. Such analysis leverages the factorial design to permit separate estimates for each","text_display":" and SMT strata. Such analysis leverages the factorial design to permit separate estimates for each","confidence":1,"confidence_rate":1},{"cnt":[[245,494],[1697,494],[1697,544],[245,544]],"region":{"top_left_x":244,"top_left_y":494,"width":1454,"height":50},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"66ea44a2cc4e4ad28fc6b42cd100b51c","type":"text","conversion_output":true,"text":"component of intervention. Notice that an additive model would use only 2 coefficient","text_display":" component of intervention. Notice that an additive model would use only 2 coefficient","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1841,541],[1841,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1598,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"afe7e06306de49f09ae61fc5b6d4cd79","type":"text","conversion_output":true,"text":"parameters to code the four treatment groups by assuming that the combined SMT+SSM group","text_display":" parameters to code the four treatment groups by assuming that the combined SMT+SSM group","confidence":1,"confidence_rate":1},{"cnt":[[245,589],[1783,589],[1783,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1540,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1bc9f2b88f944014a13b6786d8e8af75","type":"text","conversion_output":true,"text":"will have a treatment effect that is the sum of the effect for each individual component. Our","text_display":" will have a treatment effect that is the sum of the effect for each individual component. Our","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1850,636],[1850,685],[245,685]],"region":{"top_left_x":244,"top_left_y":635,"width":1606,"height":51},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"48ac7efb5f53401bb71ac437a6080a5d","type":"text","conversion_output":true,"text":"analysis does not make any additive assumptions but rather directly defines a summary contrast","text_display":" analysis does not make any additive assumptions but rather directly defines a summary contrast","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1747,683],[1747,735],[245,735]],"region":{"top_left_x":244,"top_left_y":683,"width":1503,"height":52},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f4c946bf454a45edbd3e909787410ca0","type":"text","conversion_output":true,"text":"for each treatment modality as the parameter of interest. Factorial designs are particularly","text_display":" for each treatment modality as the parameter of interest. Factorial designs are particularly","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1867,730],[1867,782],[245,782]],"region":{"top_left_x":244,"top_left_y":730,"width":1623,"height":53},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"41ac4180384245c19cbbc5e3a06753a2","type":"text","conversion_output":true,"text":"efficient when evaluating two treatment modalities that work in complementary domains such as","text_display":" efficient when evaluating two treatment modalities that work in complementary domains such as","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1837,778],[1837,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":1593,"height":55},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ea1a2e63e99f47bfba042d07c890b565","type":"text","conversion_output":true,"text":"SMT (physical) and SSM (psychological) and permit separate assessment of each intervention.","text_display":" SMT (physical) and SSM (psychological) and permit separate assessment of each intervention.","confidence":1,"confidence_rate":1},{"cnt":[[245,827],[1766,827],[1766,879],[245,879]],"region":{"top_left_x":244,"top_left_y":827,"width":1523,"height":52},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0564d6518c0244deb2fd32d1f2002675","type":"text","conversion_output":true,"text":"Formally, our primary analysis will separately test the null hypothesis H0: \\((\\beta 3+1 / 2 \\beta 5)=0\\)","text_display":" Formally, our primary analysis will separately test the null hypothesis H0: \\((\\beta 3+1 / 2 \\beta 5)=0\\)","confidence":0.9926893626123956,"confidence_rate":0.9999202478428132},{"cnt":[[245,877],[1858,877],[1858,926],[245,926]],"region":{"top_left_x":244,"top_left_y":876,"width":1615,"height":50},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4b44c89d5f6c4fc3aa3b3281e6e68c7b","type":"text","conversion_output":true,"text":"denoting no average effect of SMT, and H0:( \\(\\beta 4+1 / 2 \\beta 5\\) ) \\(=0\\) denoting no average effect of SSM.","text_display":" denoting no average effect of SMT, and H0:( \\(\\beta 4+1 / 2 \\beta 5\\) ) \\(=0\\) denoting no average effect of SSM.","confidence":0.3827893764914231,"confidence_rate":0.9907203112262759},{"cnt":[[245,924],[1721,924],[1721,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1477,"height":51},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"72b80cc96f7d4cf38f15152093ec9b36","type":"text","conversion_output":true,"text":"Each primary test will use a significance level of 0.05 without correction since each test","text_display":" Each primary test will use a significance level of 0.05 without correction since each test","confidence":0.9970703125,"confidence_rate":0.999970061800863},{"cnt":[[245,971],[1846,971],[1846,1025],[245,1025]],"region":{"top_left_x":244,"top_left_y":971,"width":1602,"height":54},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"146cb881c7494544967b39202f480965","type":"text","conversion_output":true,"text":"evaluates a separate intervention. Finally, evaluation of the interaction term using \\(S M T_{i j} \\cdot S S M_{i j}\\)","text_display":" evaluates a separate intervention. Finally, evaluation of the interaction term using \\(S M T_{i j} \\cdot S S M_{i j}\\)","confidence":1,"confidence_rate":1},{"cnt":[[243,1023],[1807,1023],[1807,1072],[243,1072]],"region":{"top_left_x":242,"top_left_y":1022,"width":1565,"height":51},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f8a05a5cedef49908c06ff5dc5c10434","type":"text","conversion_output":true,"text":"permits a formal evaluation for non-additivity by testing the interaction coefficient H 0 : \\(\\beta 5=0\\)","text_display":" permits a formal evaluation for non-additivity by testing the interaction coefficient H 0 : \\(\\beta 5=0\\)","confidence":0.7971560065634549,"confidence_rate":0.9978432350992913},{"cnt":[[245,1070],[866,1070],[866,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1069,"width":622,"height":51},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8fe54da74bae4e7aaadb7860b838fd52","type":"text","conversion_output":true,"text":"(interaction model described below).","text_display":" (interaction model described below).","confidence":1,"confidence_rate":1},{"cnt":[[245,1164],[1729,1164],[1729,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1164,"width":1486,"height":50},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c0f58230cecd40618ea2d76ce0b510ee","type":"text","conversion_output":true,"text":"Power and Sample Size for Secondary Outcome of Chronicity: In order to determine the","text_display":"\n\nPower and Sample Size for Secondary Outcome of Chronicity: In order to determine the","confidence":1,"confidence_rate":1},{"cnt":[[245,1212],[1794,1212],[1794,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":1550,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5f5d3a50ddad41b58249355bf1d55053","type":"text","conversion_output":true,"text":"necessary sample size for effectiveness evaluation we need to formulate assumptions for the","text_display":" necessary sample size for effectiveness evaluation we need to formulate assumptions for the","confidence":1,"confidence_rate":1},{"cnt":[[245,1257],[1843,1257],[1843,1311],[245,1311]],"region":{"top_left_x":244,"top_left_y":1256,"width":1600,"height":55},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6a04438c1d6a41dc880e478483dce0c7","type":"text","conversion_output":true,"text":"binary secondary outcome rate in the treated and untreated groups. Chou and Shekelle \\({ }^{34}\\) review","text_display":" binary secondary outcome rate in the treated and untreated groups. Chou and Shekelle \\({ }^{34}\\) review","confidence":1,"confidence_rate":1},{"cnt":[[245,1308],[1869,1308],[1869,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1308,"width":1626,"height":52},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6b804e7040c54a7388069ddf6c4d964e","type":"text","conversion_output":true,"text":"six studies conducted in primary care that focused on pain, functional status, or mixed outcomes.","text_display":" six studies conducted in primary care that focused on pain, functional status, or mixed outcomes.","confidence":1,"confidence_rate":1},{"cnt":[[245,1354],[1878,1354],[1878,1405],[245,1405]],"region":{"top_left_x":244,"top_left_y":1353,"width":1634,"height":53},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c4335e7d4188434499e7f33e2f892a28","type":"text","conversion_output":true,"text":"Using results from this paper we conservatively assume a rate of cLBP of \\(20 \\%\\) at 1 year. In order","text_display":" Using results from this paper we conservatively assume a rate of cLBP of \\(20 \\%\\) at 1 year. In order","confidence":0.99462890625,"confidence_rate":0.9999496688373789},{"cnt":[[245,1403],[1858,1403],[1858,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1402,"width":1615,"height":53},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"36eaf606de984241a786b7d845c54210","type":"text","conversion_output":true,"text":"to formulate appropriate effect estimates we consider detection of a relative risk of \\(RR =0.70\\) for","text_display":" to formulate appropriate effect estimates we consider detection of a relative risk of \\(RR =0.70\\) for","confidence":0.89599609375,"confidence_rate":0.9989836721292303},{"cnt":[[245,1452],[1850,1452],[1850,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1452,"width":1606,"height":50},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2b1054a60f3f48e8a0d0c4b419fe4f85","type":"text","conversion_output":true,"text":"each of SMT and SSM individually implying a reduction of the rate from \\(20 \\%\\) to \\(14 \\%\\) for these","text_display":" each of SMT and SSM individually implying a reduction of the rate from \\(20 \\%\\) to \\(14 \\%\\) for these","confidence":0.97314453125,"confidence_rate":0.9997331467298399},{"cnt":[[245,1495],[1813,1495],[1813,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1495,"width":1570,"height":55},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4d90b080936647729b26b316abb7babf","type":"text","conversion_output":true,"text":"intervention groups. Based on the Cochrane Back Review Group \\({ }^{148}\\) a relative risk of 0.70 is a","text_display":" intervention groups. Based on the Cochrane Back Review Group \\({ }^{148}\\) a relative risk of 0.70 is a","confidence":1,"confidence_rate":1},{"cnt":[[245,1547],[1772,1547],[1772,1601],[245,1601]],"region":{"top_left_x":244,"top_left_y":1546,"width":1529,"height":55},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1ac23dbe2d5d4ff0bd49c8765934db1a","type":"text","conversion_output":true,"text":"clinically relevant and medium in size intervention effect, while the assumption of additive","text_display":" clinically relevant and medium in size intervention effect, while the assumption of additive","confidence":0.99658203125,"confidence_rate":0.9999647034750034},{"cnt":[[245,1594],[1794,1594],[1794,1646],[245,1646]],"region":{"top_left_x":244,"top_left_y":1594,"width":1550,"height":52},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"be0a295572ed4b3fa74984f9f5166ae5","type":"text","conversion_output":true,"text":"effects on the probability scale would lead to a cLBP rate of \\(8 \\%\\) among those randomized to","text_display":" effects on the probability scale would lead to a cLBP rate of \\(8 \\%\\) among those randomized to","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[245,1641],[1803,1641],[1803,1695],[245,1695]],"region":{"top_left_x":244,"top_left_y":1641,"width":1559,"height":55},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"76701d9c748344e9a81df6e9847560bb","type":"text","conversion_output":true,"text":"SMT+SSM, which is considered a \"large\" treatment effect \\(( RR =0.40)\\). Therefore, we seek to","text_display":" SMT+SSM, which is considered a \"large\" treatment effect \\(( RR =0.40)\\). Therefore, we seek to","confidence":0.9960954189300537,"confidence_rate":0.9999608785267882},{"cnt":[[245,1693],[1768,1693],[1768,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1692,"width":1525,"height":51},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"36d547860b5c4c919a94e735f1dc0a3d","type":"text","conversion_output":true,"text":"design our study to detect and medium sized treatment effects, and consider power under a","text_display":" design our study to detect and medium sized treatment effects, and consider power under a","confidence":1,"confidence_rate":1},{"cnt":[[245,1740],[1807,1740],[1807,1790],[245,1790]],"region":{"top_left_x":244,"top_left_y":1740,"width":1563,"height":50},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ba1c33de7e154bc5a4c31a32309186ea","type":"text","conversion_output":true,"text":"collection of plausible scenarios. A recent cohort study of acute LBP patients in primary care","text_display":" collection of plausible scenarios. A recent cohort study of acute LBP patients in primary care","confidence":1,"confidence_rate":1},{"cnt":[[245,1788],[1783,1788],[1783,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1787,"width":1540,"height":50},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1a0315dd1ff94adb9f9671c2d67b3543","type":"text","conversion_output":true,"text":"reported a similar proportion of patients with cLBP at 2 years, but noted the estimate varied","text_display":" reported a similar proportion of patients with cLBP at 2 years, but noted the estimate varied","confidence":1,"confidence_rate":1},{"cnt":[[245,1830],[1742,1830],[1742,1886],[245,1886]],"region":{"top_left_x":244,"top_left_y":1830,"width":1499,"height":57},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9d77128e824141e1baaf779e8bd8824a","type":"text","conversion_output":true,"text":"based on the case definition \\({ }^{149}\\) and estimates based on the NIH RTF definition are not yet","text_display":" based on the case definition \\({ }^{149}\\) and estimates based on the NIH RTF definition are not yet","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1863,1882],[1863,1934],[245,1934]],"region":{"top_left_x":244,"top_left_y":1882,"width":1619,"height":52},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5a0b0fa823314d1b87ee7c93a9a56e86","type":"text","conversion_output":true,"text":"available. Relative to general LBP patients, we expect a rate of chronicity in the MC group to be","text_display":" available. Relative to general LBP patients, we expect a rate of chronicity in the MC group to be","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1729,1929],[1729,1981],[245,1981]],"region":{"top_left_x":244,"top_left_y":1929,"width":1486,"height":52},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c2a9f7fa0ac548a392687883270857d6","type":"text","conversion_output":true,"text":"larger since we are enrolling subjects at an increased risk of chronicity. Accordingly, we","text_display":" larger since we are enrolling subjects at an increased risk of chronicity. Accordingly, we","confidence":1,"confidence_rate":1},{"cnt":[[245,1977],[1880,1977],[1880,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1976,"width":1636,"height":55},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"789b5f68cf654f9684c07e8bc70f89b4","type":"text","conversion_output":true,"text":"increased the estimated proportion with cLBP in the MC group to be 30 and \\(40 \\%\\) and determined","text_display":" increased the estimated proportion with cLBP in the MC group to be 30 and \\(40 \\%\\) and determined","confidence":1,"confidence_rate":1},{"cnt":[[245,2024],[1833,2024],[1833,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2023,"width":1589,"height":55},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a21ff7f0e45944c3b0c09ef9ab69acb2","type":"text","conversion_output":true,"text":"the magnitude of treatment effects for which we have \\(\\geq 80 \\%\\) power. At 1 year, we assume that","text_display":" the magnitude of treatment effects for which we have \\(\\geq 80 \\%\\) power. At 1 year, we assume that","confidence":1,"confidence_rate":1},{"cnt":[[245,2075],[1798,2075],[1798,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2075,"width":1555,"height":50},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3a1a324fba074cfa8e2593e080085139","type":"text","conversion_output":true,"text":"we will have at least \\(88 \\%\\) follow-up based on prior studies conducted at the clinical research","text_display":" we will have at least \\(88 \\%\\) follow-up based on prior studies conducted at the clinical research","confidence":0.998046875,"confidence_rate":0.9999806434067887},{"cnt":[[245,2118],[1852,2118],[1852,2174],[245,2174]],"region":{"top_left_x":244,"top_left_y":2118,"width":1608,"height":57},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5aa7b27ee28b46c89664ebd7341f4ab2","type":"text","conversion_output":true,"text":"sites and studies \\({ }^{11}{ }^{150}\\) with similar incentives \\({ }^{151}\\). Thus, with \\(n =1000\\) enrolled subjects we expect","text_display":" sites and studies \\({ }^{11}{ }^{150}\\) with similar incentives \\({ }^{151}\\). Thus, with \\(n =1000\\) enrolled subjects we expect","confidence":0.7009223022032529,"confidence_rate":0.9974095053954515},{"cnt":[[245,2170],[1233,2170],[1233,2221],[245,2221]],"region":{"top_left_x":244,"top_left_y":2169,"width":990,"height":53},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"23e786d06fcf4fa4988fa7732efca7e2","type":"text","conversion_output":true,"text":"at least \\(n =880\\) total subjects available for primary analysis.","text_display":" at least \\(n =880\\) total subjects available for primary analysis.","confidence":0.9970703125,"confidence_rate":0.9999592510047797},{"cnt":[[245,2264],[1878,2264],[1878,2316],[245,2316]],"region":{"top_left_x":244,"top_left_y":2264,"width":1634,"height":53},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9fdb13bbede5496e8018763223bc41bb","type":"text","conversion_output":true,"text":"Our original sample size was chosen as \\(n=1180\\) (since modified to \\(n=1000\\) ) to ensure \\(80 \\%\\) power","text_display":"\n\nOur original sample size was chosen as \\(n=1180\\) (since modified to \\(n=1000\\) ) to ensure \\(80 \\%\\) power","confidence":0.9960954189300537,"confidence_rate":0.9999634378287147},{"cnt":[[245,2314],[1871,2314],[1871,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2313,"width":1628,"height":53},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1565a32413044aa2a07ddb8a53c99acf","type":"text","conversion_output":true,"text":"assuming an additive model with a chronic rate of \\(20 \\%\\) in UMC and a medium relative risk (RR)","text_display":" assuming an additive model with a chronic rate of \\(20 \\%\\) in UMC and a medium relative risk (RR)","confidence":0.9990236759185791,"confidence_rate":0.9999902320377446},{"cnt":[[245,2363],[1742,2363],[1742,2413],[245,2413]],"region":{"top_left_x":244,"top_left_y":2363,"width":1499,"height":50},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"82250c41a915420fbca0577df5dd624f","type":"text","conversion_output":true,"text":"of 0.70 . To evaluate power we conducted simulations using the R statistical package. We","text_display":" of 0.70 . To evaluate power we conducted simulations using the R statistical package. We","confidence":0.9902389049530029,"confidence_rate":0.9999038374981088},{"cnt":[[245,2411],[1785,2411],[1785,2462],[245,2462]],"region":{"top_left_x":244,"top_left_y":2410,"width":1542,"height":53},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f879c84777c947e0bb7d1551da9483cb","type":"text","conversion_output":true,"text":"generated data under various additive assumptions. For analysis we first considered a single","text_display":" generated data under various additive assumptions. For analysis we first considered a single","confidence":0.99951171875,"confidence_rate":0.9999949649559944},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":44,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"7ee20e2538014119b1891ac03415a07b","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 63","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-64","page":64,"lines":[{"cnt":[[245,254],[1729,254],[1729,303],[245,303]],"region":{"top_left_x":244,"top_left_y":253,"width":1486,"height":50},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"67afadaced6842d8825fc3fe24b75924","type":"text","conversion_output":true,"text":"likelihood ratio test of one treatment modality (either SMT or SSM). For simulations we","text_display":"\nlikelihood ratio test of one treatment modality (either SMT or SSM). For simulations we","confidence":0.99951171875,"confidence_rate":0.9999946913130248},{"cnt":[[245,301],[1858,301],[1858,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1615,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dc33d5708afe49c994aa896616b3bc66","type":"text","conversion_output":true,"text":"considered crude analysis while our formal analysis will additionally adjust for site and baseline","text_display":" considered crude analysis while our formal analysis will additionally adjust for site and baseline","confidence":0.99951171875,"confidence_rate":0.9999952582588333},{"cnt":[[245,348],[1863,348],[1863,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1619,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e832609a1d9449269b9856f31d9915be","type":"text","conversion_output":true,"text":"risk and therefore improve power since these are variables that only predict outcome and are not","text_display":" risk and therefore improve power since these are variables that only predict outcome and are not","confidence":1,"confidence_rate":1},{"cnt":[[245,397],[1762,397],[1762,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":1518,"height":53},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"84499aa93c674b30a020ebe3ee61c1fe","type":"text","conversion_output":true,"text":"related to treatment group. For each scenario we simulated 5,000 data sets and empirically","text_display":" related to treatment group. For each scenario we simulated 5,000 data sets and empirically","confidence":0.82177734375,"confidence_rate":0.9979990882536599},{"cnt":[[245,447],[1760,447],[1760,496],[245,496]],"region":{"top_left_x":244,"top_left_y":446,"width":1516,"height":51},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0bbf05a01b6c442ca3009a664150ee5a","type":"text","conversion_output":true,"text":"calculated power as the percentage of replicates in which the null hypothesis was rejected.","text_display":" calculated power as the percentage of replicates in which the null hypothesis was rejected.","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1798,541],[1798,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1555,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"667ff76839554d5f92ed893fe39ba98d","type":"text","conversion_output":true,"text":"Using simulations with \\(n =1000\\) subjects, \\(90 \\%\\) follow-up, and accounting for our imbalanced","text_display":"\n\nUsing simulations with \\(n =1000\\) subjects, \\(90 \\%\\) follow-up, and accounting for our imbalanced","confidence":1,"confidence_rate":1},{"cnt":[[245,589],[1824,589],[1824,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1581,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"876eb41625a14c13a9929fdda33a98b3","type":"text","conversion_output":true,"text":"allocation due to COVID interruption we compute power for analyses that consider individual","text_display":" allocation due to COVID interruption we compute power for analyses that consider individual","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1858,636],[1858,685],[245,685]],"region":{"top_left_x":244,"top_left_y":635,"width":1615,"height":51},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1c94836fdb29493f9a41802704f0a543","type":"text","conversion_output":true,"text":"marginal treatment effects for both SMT and SSM. If we assume a UMC chronicity rate of \\(20 \\%\\)","text_display":" marginal treatment effects for both SMT and SSM. If we assume a UMC chronicity rate of \\(20 \\%\\)","confidence":0.9752426147460938,"confidence_rate":0.9997333440345371},{"cnt":[[245,683],[1725,683],[1725,733],[245,733]],"region":{"top_left_x":244,"top_left_y":683,"width":1482,"height":50},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"82b6fa67063548219ae1e3fb676c7f67","type":"text","conversion_output":true,"text":"and a relative risk of 0.65 (rate under treatment \\(=20 \\% * 0.65=13 \\%\\), or an absolute risk","text_display":" and a relative risk of 0.65 (rate under treatment \\(=20 \\% * 0.65=13 \\%\\), or an absolute risk","confidence":0.998046875,"confidence_rate":0.9999796352611579},{"cnt":[[245,730],[1790,730],[1790,780],[245,780]],"region":{"top_left_x":244,"top_left_y":730,"width":1546,"height":50},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ab2d0755ca154dc490e1b9ea8f6bc7be","type":"text","conversion_output":true,"text":"reduction of \\(7 \\%\\) ) then we have \\(>85 \\%\\) power to detect average SSM or SMT effects. If we a","text_display":" reduction of \\(7 \\%\\) ) then we have \\(>85 \\%\\) power to detect average SSM or SMT effects. If we a","confidence":0.9975595474243164,"confidence_rate":0.9999750672972136},{"cnt":[[245,778],[1865,778],[1865,829],[245,829]],"region":{"top_left_x":244,"top_left_y":777,"width":1621,"height":53},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e3a13bd3dd824fcf9ca38eb0fe65215e","type":"text","conversion_output":true,"text":"smaller effect corresponding to a relative risk of 0.70 (rate under treatment \\(=20 \\% * 0.70=13 \\%\\),","text_display":" smaller effect corresponding to a relative risk of 0.70 (rate under treatment \\(=20 \\% * 0.70=13 \\%\\),","confidence":1,"confidence_rate":1},{"cnt":[[245,827],[1828,827],[1828,879],[245,879]],"region":{"top_left_x":244,"top_left_y":827,"width":1585,"height":52},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c04d31c068e64b079be68f1190faf9a8","type":"text","conversion_output":true,"text":"or an absolute risk reduction of \\(7 \\%\\) ) then we have approximately \\(70 \\%\\) power to detect average","text_display":" or an absolute risk reduction of \\(7 \\%\\) ) then we have approximately \\(70 \\%\\) power to detect average","confidence":0.99951171875,"confidence_rate":0.9999952582588333},{"cnt":[[245,872],[1854,872],[1854,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1611,"height":54},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"84211eaba58747d081627d25a7b3fb33","type":"text","conversion_output":true,"text":"SSM or SMT effects of this magnitude (specifically accounting for imbalance power is \\(72 \\%\\) for","text_display":" SSM or SMT effects of this magnitude (specifically accounting for imbalance power is \\(72 \\%\\) for","confidence":0.974609375,"confidence_rate":0.9997428477764225},{"cnt":[[245,924],[1854,924],[1854,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1611,"height":51},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e234ab7bb60c4b1e82c888ff5a838596","type":"text","conversion_output":true,"text":"SSM and \\(70 \\%\\) for SMT). Power is greater for any relative risk when the UMC rate is increased","text_display":" SSM and \\(70 \\%\\) for SMT). Power is greater for any relative risk when the UMC rate is increased","confidence":0.9990234375,"confidence_rate":0.9999901309613475},{"cnt":[[245,971],[1861,971],[1861,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1617,"height":50},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9ca9d6db7c624567bb073c2bdbc199d6","type":"text","conversion_output":true,"text":"to \\(30 \\%\\) or \\(40 \\%\\). These relative risk effect sizes equate to medium effect sizes and are considered","text_display":" to \\(30 \\%\\) or \\(40 \\%\\). These relative risk effect sizes equate to medium effect sizes and are considered","confidence":0.99951171875,"confidence_rate":0.9999954777833909},{"cnt":[[245,1016],[1818,1016],[1818,1072],[245,1072]],"region":{"top_left_x":244,"top_left_y":1016,"width":1574,"height":57},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"965e59ac5a384a80abbbff0a4b384f64","type":"text","conversion_output":true,"text":"clinically important by Cochrane's Back Review Group. \\({ }^{148}\\) We have not powered the study to","text_display":" clinically important by Cochrane's Back Review Group. \\({ }^{148}\\) We have not powered the study to","confidence":1,"confidence_rate":1},{"cnt":[[245,1068],[1858,1068],[1858,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1067,"width":1615,"height":53},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a6ed42677fb54fdc953c04366d82e55f","type":"text","conversion_output":true,"text":"detect interaction for the binary chronicity endpoint, but rather have powered the study to detect","text_display":" detect interaction for the binary chronicity endpoint, but rather have powered the study to detect","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1446,1113],[1446,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1202,"height":55},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9bb3a266210c4eed80615e5634b9c92d","type":"text","conversion_output":true,"text":"interaction on the underlying function and disability scales (see below).","text_display":" interaction on the underlying function and disability scales (see below).","confidence":1,"confidence_rate":1},{"cnt":[[245,1212],[1850,1212],[1850,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":1606,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c9cc3a9a96584787bd31f30dfa310036","type":"text","conversion_output":true,"text":"Furthermore, we have excellent power to detect interaction effects where the effect of SMT and","text_display":"\n\nFurthermore, we have excellent power to detect interaction effects where the effect of SMT and","confidence":1,"confidence_rate":1},{"cnt":[[245,1259],[1880,1259],[1880,1311],[245,1311]],"region":{"top_left_x":244,"top_left_y":1258,"width":1636,"height":53},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bcea370c220549589c08346a3234ffa7","type":"text","conversion_output":true,"text":"SSM may be synergistic or antagonistic, and using alpha \\(=0.05\\) we have \\(>80 \\%\\) to detect a X-point","text_display":" SSM may be synergistic or antagonistic, and using alpha \\(=0.05\\) we have \\(>80 \\%\\) to detect a X-point","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1867,1306],[1867,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1306,"width":1623,"height":54},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5e635de034934160b3430cc7281d3b21","type":"text","conversion_output":true,"text":"difference in LBP Impact treatment effects of one modality across the strata defined by the other","text_display":" difference in LBP Impact treatment effects of one modality across the strata defined by the other","confidence":0.9990236759185791,"confidence_rate":0.9999904235654993},{"cnt":[[245,1354],[578,1354],[578,1407],[245,1407]],"region":{"top_left_x":244,"top_left_y":1353,"width":334,"height":55},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f00860c522dd434fab1c72dbd03a5bda","type":"text","conversion_output":true,"text":"treatment modality.","text_display":" treatment modality.","confidence":1,"confidence_rate":1},{"cnt":[[245,1448],[1824,1448],[1824,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1448,"width":1581,"height":54},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"811549b6f8de40f4af4fca9260017900","type":"text","conversion_output":true,"text":"Secondary Effectiveness Outcome of Recovery: Determine the effectiveness of SMT, SSM,","text_display":"\n\nSecondary Effectiveness Outcome of Recovery: Determine the effectiveness of SMT, SSM,","confidence":1,"confidence_rate":1},{"cnt":[[245,1500],[1850,1500],[1850,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1499,"width":1606,"height":51},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f85b84f7c3d54f898575c26cb4941f34","type":"text","conversion_output":true,"text":"and the combination of SMT+SSM relative to medical care (UMC) in promoting recovery from","text_display":" and the combination of SMT+SSM relative to medical care (UMC) in promoting recovery from","confidence":1,"confidence_rate":1},{"cnt":[[245,1547],[844,1547],[844,1592],[245,1592]],"region":{"top_left_x":244,"top_left_y":1546,"width":601,"height":46},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bbd938604403491e973cf08c3a109805","type":"text","conversion_output":true,"text":"acute or subacute LBP at 6 months.","text_display":" acute or subacute LBP at 6 months.","confidence":1,"confidence_rate":1},{"cnt":[[245,1641],[1764,1641],[1764,1693],[245,1693]],"region":{"top_left_x":244,"top_left_y":1641,"width":1520,"height":52},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"885b40161fcd444587ca37571e615d45","type":"text","conversion_output":true,"text":"In 2021, the NIH statistician overseeing the trial raised the question of the adequacy of the","text_display":"\n\nIn 2021, the NIH statistician overseeing the trial raised the question of the adequacy of the","confidence":1,"confidence_rate":1},{"cnt":[[245,1689],[1781,1689],[1781,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1688,"width":1538,"height":55},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"12242708808f4cae966114a010d44d0c","type":"text","conversion_output":true,"text":"planned adjustment for multiplicity given the trial's three main effectiveness objectives and","text_display":" planned adjustment for multiplicity given the trial's three main effectiveness objectives and","confidence":0.998046875,"confidence_rate":0.9999800508639274},{"cnt":[[245,1738],[1712,1738],[1712,1790],[245,1790]],"region":{"top_left_x":244,"top_left_y":1738,"width":1469,"height":52},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e8aebd6b4f0d46148e8cde1b569cb489","type":"text","conversion_output":true,"text":"accompanying four co-primary outcome measures. In response to this concern, the lead","text_display":" accompanying four co-primary outcome measures. In response to this concern, the lead","confidence":0.99951171875,"confidence_rate":0.9999945123690109},{"cnt":[[245,1783],[1779,1783],[1779,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1783,"width":1535,"height":54},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bec764dbe975472895d804e68346efee","type":"text","conversion_output":true,"text":"investigators recommended the recovery objective be changed to a key secondary outcome.","text_display":" investigators recommended the recovery objective be changed to a key secondary outcome.","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1790,1835],[1790,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1546,"height":51},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ea3de9f7bf554e62814f4ce4015418f1","type":"text","conversion_output":true,"text":"Early in the conduct of the trial it was decided and approved as a protocol change to include","text_display":" Early in the conduct of the trial it was decided and approved as a protocol change to include","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1779,1882],[1779,1934],[245,1934]],"region":{"top_left_x":244,"top_left_y":1882,"width":1535,"height":52},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"71bbabf0d61a4917bf5eb6e4cf9225d8","type":"text","conversion_output":true,"text":"patients that had an acute aggravation of ongoing LBP, if the ongoing pain was not rated as","text_display":" patients that had an acute aggravation of ongoing LBP, if the ongoing pain was not rated as","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1764,1929],[1764,1979],[245,1979]],"region":{"top_left_x":244,"top_left_y":1929,"width":1520,"height":50},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ec7e94497df04dc3a27439f1c39ed4c5","type":"text","conversion_output":true,"text":"severe in the month prior to the aggravation. This protocol change substantially lowers the","text_display":" severe in the month prior to the aggravation. This protocol change substantially lowers the","confidence":1,"confidence_rate":1},{"cnt":[[245,1977],[1863,1977],[1863,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1976,"width":1619,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ae03cf08bae94362b1c277f2c0d5843f","type":"text","conversion_output":true,"text":"proportion of patients that can be expected to recover according to our criteria (pain severity \\(=0\\)","text_display":" proportion of patients that can be expected to recover according to our criteria (pain severity \\(=0\\)","confidence":0.9931671619415283,"confidence_rate":0.999932783741655},{"cnt":[[245,2024],[1867,2024],[1867,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2023,"width":1623,"height":55},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c434a974cde0456f8c3ebf7a2ca55e40","type":"text","conversion_output":true,"text":"and RMD score \\(\\leq 2\\) ). Given this change, the recovery outcome was less appropriate as a primary","text_display":" and RMD score \\(\\leq 2\\) ). Given this change, the recovery outcome was less appropriate as a primary","confidence":0.99951171875,"confidence_rate":0.9999951643631956},{"cnt":[[245,2073],[1835,2073],[1835,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2073,"width":1591,"height":52},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b5ee2bd2a675473db87fdc966600dc52","type":"text","conversion_output":true,"text":"effectiveness objective and demoting it to a secondary outcome mitigates the concern of cross-","text_display":" effectiveness objective and demoting it to a secondary outcome mitigates the concern of cross","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[750,2123],[750,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2122,"width":506,"height":51},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a9615853d6df49b290c0998932314cf3","type":"text","conversion_output":true,"text":"objective multiplicity control.","text_display":"objective multiplicity control.","confidence":1,"confidence_rate":1},{"cnt":[[245,2217],[1717,2217],[1717,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2217,"width":1473,"height":54},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cb647e4f7766467fb73a1e3f3a928b0f","type":"text","conversion_output":true,"text":"In 2022 NCCIH and the DSMB approved that the recovery effectiveness objective,","text_display":"\n\nIn 2022 NCCIH and the DSMB approved that the recovery effectiveness objective,","confidence":1,"confidence_rate":1},{"cnt":[[245,2264],[1691,2264],[1691,2316],[245,2316]],"region":{"top_left_x":244,"top_left_y":2264,"width":1447,"height":53},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"35f659762b104792949bdea80a00bde9","type":"text","conversion_output":true,"text":"formally one of the 3 primary effectiveness objectives, will be designated as a key","text_display":" formally one of the 3 primary effectiveness objectives, will be designated as a key","confidence":0.994140625,"confidence_rate":0.999935423969858},{"cnt":[[245,2316],[608,2316],[608,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2316,"width":365,"height":50},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5a1a1269cd404df79f3671b28a110dd5","type":"text","conversion_output":true,"text":"secondary outcome.","text_display":" secondary outcome.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":40,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"77e6494d9d1a411bbf027ece0dd0f0a1","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 64","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-65","page":65,"lines":[{"cnt":[[245,254],[1854,254],[1854,303],[245,303]],"region":{"top_left_x":244,"top_left_y":253,"width":1611,"height":50},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"77d372dba74e4c1a8b5acc4ce9309e9c","type":"text","conversion_output":true,"text":"Recovery Effectiveness Hypothesis: SMT alone will increase the rate of recovery by 5.5-7.5\\%","text_display":"\n\nRecovery Effectiveness Hypothesis: SMT alone will increase the rate of recovery by 5.5-7.5\\%","confidence":0.85400390625,"confidence_rate":0.9983573973098971},{"cnt":[[245,301],[1790,301],[1790,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1546,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"38d67146c39140cabc71df23fc8d3011","type":"text","conversion_output":true,"text":"or more from a baseline MC rate of \\(5 \\%-15 \\%\\). Similarly, SSM alone will increase the rate of","text_display":" or more from a baseline MC rate of \\(5 \\%-15 \\%\\). Similarly, SSM alone will increase the rate of","confidence":0.994140625,"confidence_rate":0.9999400364051435},{"cnt":[[245,348],[1863,348],[1863,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1619,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c0bd65a925da466ca68fcfe37e4d5580","type":"text","conversion_output":true,"text":"recovery from \\(5.5-7.5 \\%\\), and the combination of SMT+SSM will lead to an additive net increase","text_display":" recovery from \\(5.5-7.5 \\%\\), and the combination of SMT+SSM will lead to an additive net increase","confidence":0.9853515625,"confidence_rate":0.9998539038884641},{"cnt":[[245,397],[587,397],[587,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":343,"height":53},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"793ed18713bb4c93b5bb59d8fe67ac29","type":"text","conversion_output":true,"text":"in the recovery rate.","text_display":" in the recovery rate.","confidence":1,"confidence_rate":1},{"cnt":[[245,492],[1800,492],[1800,544],[245,544]],"region":{"top_left_x":244,"top_left_y":491,"width":1557,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9714547494364de09536c1c46df2dcdf","type":"text","conversion_output":true,"text":"Recovery outcome definition: For a patient to be classified as recovered at the 6 month or 1","text_display":"\n\nRecovery outcome definition: For a patient to be classified as recovered at the 6 month or 1","confidence":1,"confidence_rate":1},{"cnt":[[245,537],[1798,537],[1798,591],[245,591]],"region":{"top_left_x":244,"top_left_y":537,"width":1555,"height":54},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"64a73ca1bb2d4439ab8104c4cec77096","type":"text","conversion_output":true,"text":"year assessment they must endorse both an NRS of 0 , and an RMDQ of \\(<=2 .{ }^{152}\\) To evaluate","text_display":" year assessment they must endorse both an NRS of 0 , and an RMDQ of \\(<=2 .{ }^{152}\\) To evaluate","confidence":0.9534391108900309,"confidence_rate":0.9995460105652384},{"cnt":[[245,589],[1639,589],[1639,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1396,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"998524cfa0c848f39ce725bda64d60fd","type":"text","conversion_output":true,"text":"recovery we will consider the 6 -month status first and use the 1 -year status second.","text_display":" recovery we will consider the 6 -month status first and use the 1 -year status second.","confidence":0.9313773172907531,"confidence_rate":0.9992673736350465},{"cnt":[[245,683],[1871,683],[1871,737],[245,737]],"region":{"top_left_x":244,"top_left_y":683,"width":1628,"height":54},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"346db071dc264aefb506d3f67776e7f4","type":"text","conversion_output":true,"text":"Recovery Analysis: The primary analysis will be two parallel tests of the average effects of SMT","text_display":"\n\nRecovery Analysis: The primary analysis will be two parallel tests of the average effects of SMT","confidence":0.99951171875,"confidence_rate":0.9999951643631956},{"cnt":[[245,730],[1871,730],[1871,784],[245,784]],"region":{"top_left_x":244,"top_left_y":730,"width":1628,"height":55},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9c2895a6351148e5908bf5a2d3c459af","type":"text","conversion_output":true,"text":"and SSM in a full logistic regression model for the primary outcome (recovery at 6 months). The","text_display":" and SSM in a full logistic regression model for the primary outcome (recovery at 6 months). The","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1751,778],[1751,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":1507,"height":55},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4d6dbc2901f347cd85207f786eaebaab","type":"text","conversion_output":true,"text":"primary analysis for recovery will use pre-specified linear contrasts for hypothesis testing","text_display":" primary analysis for recovery will use pre-specified linear contrasts for hypothesis testing","confidence":1,"confidence_rate":1},{"cnt":[[245,829],[855,829],[855,879],[245,879]],"region":{"top_left_x":244,"top_left_y":829,"width":612,"height":50},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d72206e1a7b144a8a5dcaf0a25cf9703","type":"text","conversion_output":true,"text":"regarding overall or average effects.","text_display":" regarding overall or average effects.","confidence":1,"confidence_rate":1},{"cnt":[[245,922],[1841,922],[1841,975],[245,975]],"region":{"top_left_x":244,"top_left_y":921,"width":1598,"height":55},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"49ba2a7827cb49bfaeb3db15ebb5b460","type":"text","conversion_output":true,"text":"Power and Sample Size for the Recovery Outcome: In order to determine the necessary sample","text_display":"\n\nPower and Sample Size for the Recovery Outcome: In order to determine the necessary sample","confidence":1,"confidence_rate":1},{"cnt":[[245,971],[1858,971],[1858,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1615,"height":50},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0a9c24df9663459aab89bb362695a45a","type":"text","conversion_output":true,"text":"size for effectiveness evaluation we need to formulate assumptions for the primary outcome rate","text_display":" size for effectiveness evaluation we need to formulate assumptions for the primary outcome rate","confidence":1,"confidence_rate":1},{"cnt":[[245,1016],[1826,1016],[1826,1072],[245,1072]],"region":{"top_left_x":244,"top_left_y":1016,"width":1583,"height":57},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"99d70c2695864b128425742ea7a87c83","type":"text","conversion_output":true,"text":"in the treatment and control groups. Bronfort et al. \\({ }^{11}\\) compared SMT plus Home Exercise with","text_display":" in the treatment and control groups. Bronfort et al. \\({ }^{11}\\) compared SMT plus Home Exercise with","confidence":1,"confidence_rate":1},{"cnt":[[245,1068],[1833,1068],[1833,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1067,"width":1589,"height":53},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b53bb5fbf0f84477a0ccf1edff52ed2b","type":"text","conversion_output":true,"text":"Advice (HEA) to HEA alone among subacute and chronic patients and find complete recovery","text_display":" Advice (HEA) to HEA alone among subacute and chronic patients and find complete recovery","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1794,1113],[1794,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1550,"height":55},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"14405663b51e49108d7af97458049018","type":"text","conversion_output":true,"text":"from leg pain in 20\\% of SMT+HEA versus 5\\% of HEA at 12 weeks, and \\(23 \\%\\) versus \\(12.5 \\%\\)","text_display":" from leg pain in 20\\% of SMT+HEA versus 5\\% of HEA at 12 weeks, and \\(23 \\%\\) versus \\(12.5 \\%\\)","confidence":0.5596522567793727,"confidence_rate":0.9937107340307771},{"cnt":[[245,1162],[1850,1162],[1850,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1606,"height":52},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6dff7b6f00ef4a5a81ce62f7ce246254","type":"text","conversion_output":true,"text":"respectively at one year \\(( RR =1.84)\\) providing evidence that relative risks in the range of 1.5-2.0","text_display":" respectively at one year \\(( RR =1.84)\\) providing evidence that relative risks in the range of 1.5-2.0","confidence":0.9781445935368538,"confidence_rate":0.9997954119150408},{"cnt":[[245,1207],[1848,1207],[1848,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1207,"width":1604,"height":55},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e804b4ba4afb492492ec145d2337ee1b","type":"text","conversion_output":true,"text":"are plausible. The recovery rate at 6 months was estimated based on studies by Kamper et al. \\({ }^{152}\\)","text_display":" are plausible. The recovery rate at 6 months was estimated based on studies by Kamper et al. \\({ }^{152}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1255],[1803,1255],[1803,1311],[245,1311]],"region":{"top_left_x":244,"top_left_y":1254,"width":1559,"height":57},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"57c2d51e74b24636b3d2231ee2af9980","type":"text","conversion_output":true,"text":"and members of our investigative team, \\({ }^{153}\\) which used the same strict definition for recovery.","text_display":" and members of our investigative team, \\({ }^{153}\\) which used the same strict definition for recovery.","confidence":1,"confidence_rate":1},{"cnt":[[245,1302],[1871,1302],[1871,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1301,"width":1628,"height":59},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ad47bad6e6f847cfb51c2515a20409e7","type":"text","conversion_output":true,"text":"Kamper et al. \\({ }^{152}\\) summarize recovery rates and criteria based on both NRS and RMDQ from four","text_display":" Kamper et al. \\({ }^{152}\\) summarize recovery rates and criteria based on both NRS and RMDQ from four","confidence":1,"confidence_rate":1},{"cnt":[[245,1354],[1850,1354],[1850,1405],[245,1405]],"region":{"top_left_x":244,"top_left_y":1353,"width":1606,"height":53},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"90cea3c38dd3435386f20928e6256af8","type":"text","conversion_output":true,"text":"studies with acute and subacute subjects. Recovery rates range from \\(7 \\%\\) to \\(12 \\%\\). A recent study","text_display":" studies with acute and subacute subjects. Recovery rates range from \\(7 \\%\\) to \\(12 \\%\\). A recent study","confidence":1,"confidence_rate":1},{"cnt":[[245,1399],[1772,1399],[1772,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1398,"width":1529,"height":57},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0a6936c3b0614445a0733159585f08c8","type":"text","conversion_output":true,"text":"by George et al. \\({ }^{153}\\) reported a \\(5 \\%\\) recovery rate within a mixed population of sub-acute and","text_display":" by George et al. \\({ }^{153}\\) reported a \\(5 \\%\\) recovery rate within a mixed population of sub-acute 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Given the potential uncertainty","confidence":0.9975595474243164,"confidence_rate":0.9999418246604909},{"cnt":[[1216,1547],[1867,1547],[1867,1601],[1216,1601]],"region":{"top_left_x":1216,"top_left_y":1546,"width":651,"height":55},"line":32,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a787dd3825164d1d8687262be8134bc7","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"in the recovery rate for the MC group,","text_display":" in the recovery rate for the MC group,","confidence":0.99951171875,"confidence_rate":0.9999886419133848},{"cnt":[[1216,1594],[1841,1594],[1841,1646],[1216,1646]],"region":{"top_left_x":1216,"top_left_y":1594,"width":626,"height":52},"line":33,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4f9db804ff4b4a959f232981622146d8","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"we varied the expected recovery rate","text_display":" we 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For each scenario we","text_display":" treatment group. For each scenario we","confidence":1,"confidence_rate":1},{"cnt":[[1216,2170],[1721,2170],[1721,2219],[1216,2219]],"region":{"top_left_x":1216,"top_left_y":2169,"width":505,"height":51},"line":44,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c4ac83612d024ccd93624915d7f117e9","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"simulated 5,000 data sets and","text_display":" simulated 5,000 data sets and","confidence":0.99951171875,"confidence_rate":0.9999856353826395},{"cnt":[[1216,2217],[1820,2217],[1820,2271],[1216,2271]],"region":{"top_left_x":1216,"top_left_y":2217,"width":604,"height":54},"line":45,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"176f58ff70d64017a8ecd4fba66cf1cf","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"empirically calculated power as the","text_display":" empirically calculated power as the","confidence":1,"confidence_rate":1},{"cnt":[[1216,2264],[1841,2264],[1841,2318],[1216,2318]],"region":{"top_left_x":1216,"top_left_y":2264,"width":626,"height":55},"line":46,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7291e9a0183c48129fcf5c3a8c2bc65b","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"percentage of replicates in which the","text_display":" percentage of replicates in which the","confidence":1,"confidence_rate":1},{"cnt":[[1216,2316],[1710,2316],[1710,2365],[1216,2365]],"region":{"top_left_x":1216,"top_left_y":2316,"width":495,"height":50},"line":47,"column":2,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"08bfe6ab82a74481a737de8a75108d6e","type":"text","conversion_output":true,"parent_id":"63282388daad4a10a9272979970bff29","text":"null hypothesis was rejected.","text_display":" null hypothesis was rejected.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1850,2582],[1850,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":347,"height":37},"line":48,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"9e49e0768bbd45f3bdfb12ba4989b840","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page","text_display":"","confidence":1,"confidence_rate":1},{"cnt":[[1846,2582],[1882,2582],[1882,2617],[1846,2617]],"region":{"top_left_x":1845,"top_left_y":2582,"width":38,"height":35},"line":49,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"7539136f5b1a4395916c62d0e65bb71e","type":"page_info","conversion_output":false,"text":"65","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-66","page":66,"lines":[{"cnt":[[243,249],[1794,249],[1794,303],[243,303]],"region":{"top_left_x":242,"top_left_y":249,"width":1552,"height":54},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"acb86bcc301240d69980abf3d8dd1490","type":"text","conversion_output":true,"text":"Figure 9.2 shows the power to test each intervention marginally. We see that we have \\(>80 \\%\\)","text_display":"\n\nFigure 9.2 shows the power to test each intervention marginally. We see that we have \\(>80 \\%\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,301],[1846,301],[1846,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1602,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b0156222fab140718c5672ccb8aced65","type":"text","conversion_output":true,"text":"power to detect a relative risk of 1.75 associated with either SMT or SSM if the UMC recovery","text_display":" power to detect a relative risk of 1.75 associated with either SMT or SSM if the UMC recovery","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1867,348],[1867,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1623,"height":50},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2315a2267d5b4f99af2245d5cc233d30","type":"text","conversion_output":true,"text":"rate is \\(10 \\%\\). If the UMC recovery rate is \\(5 \\%\\) then we have power to detect a \\(5.5 \\%\\) risk difference","text_display":" rate is \\(10 \\%\\). If the UMC recovery rate is \\(5 \\%\\) then we have power to detect a \\(5.5 \\%\\) risk difference","confidence":0.9912352278038814,"confidence_rate":0.9999199722138674},{"cnt":[[245,397],[1803,397],[1803,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":1559,"height":53},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1c28f99fd9714e7090aa969f2614d6b3","type":"text","conversion_output":true,"text":"( \\(RR =2.1\\) ), while if the UMC recovery rate is \\(15 \\%\\) then we have power to detect an \\(8.3 \\%\\) risk","text_display":" ( \\(RR =2.1\\) ), while if the UMC recovery rate is \\(15 \\%\\) then we have power to detect an \\(8.3 \\%\\) risk","confidence":0.6763494031216055,"confidence_rate":0.9963857557908447},{"cnt":[[245,443],[1863,443],[1863,494],[245,494]],"region":{"top_left_x":244,"top_left_y":442,"width":1619,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"204ae63ba23646cda00fbee43aeb0a4e","type":"text","conversion_output":true,"text":"difference \\(( RR =1.55)\\). These effects are also medium in size and considered clinically important","text_display":" difference \\(( RR =1.55)\\). These effects are also medium in size and considered clinically important","confidence":0.9290723342501268,"confidence_rate":0.9993126785500058},{"cnt":[[245,488],[902,488],[902,544],[245,544]],"region":{"top_left_x":244,"top_left_y":487,"width":659,"height":57},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8f9a62c3980044fbb1fb7d637088112e","type":"text","conversion_output":true,"text":"by Cochrane's Back Review Group. \\({ }^{148}\\)","text_display":" by Cochrane's Back Review Group. \\({ }^{148}\\)","confidence":0.95654296875,"confidence_rate":0.9990551367026873},{"cnt":[[245,589],[1867,589],[1867,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1623,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d02d0dd1daf2426fb328a4ef03021c90","type":"text","conversion_output":true,"text":"Primary Effectiveness Outcome \\# 2 and 3: Determine the effectiveness of SMT, SSM, and the","text_display":"\n\nPrimary Effectiveness Outcome \\# 2 and 3: Determine the effectiveness of SMT, SSM, and the","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1863,636],[1863,690],[245,690]],"region":{"top_left_x":244,"top_left_y":635,"width":1619,"height":55},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"315112c761434a33af4b277081bc4205","type":"text","conversion_output":true,"text":"combination of SMT+SSM relative to medical care (MC) in achieving improvements in average","text_display":" combination of SMT+SSM relative to medical care (MC) in achieving improvements in average","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1742,683],[1742,737],[245,737]],"region":{"top_left_x":244,"top_left_y":683,"width":1499,"height":54},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3ae3d1a498e240fca4cab33fd567dafa","type":"text","conversion_output":true,"text":"pain intensity and back-specific functioning cumulative through 1 year based on monthly","text_display":" pain intensity and back-specific functioning cumulative through 1 year based on monthly","confidence":0.99951171875,"confidence_rate":0.9999948589553403},{"cnt":[[245,733],[1094,733],[1094,782],[245,782]],"region":{"top_left_x":244,"top_left_y":732,"width":850,"height":51},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1367a949554d4c839412b0a71d2ca923","type":"text","conversion_output":true,"text":"measures of RMDQ and weekly Pain NRS scores.","text_display":" measures of RMDQ and weekly Pain NRS scores.","confidence":1,"confidence_rate":1},{"cnt":[[245,827],[1734,827],[1734,879],[245,879]],"region":{"top_left_x":244,"top_left_y":827,"width":1490,"height":52},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"08fc53df842a4afcacce6b36be509787","type":"text","conversion_output":true,"text":"Effectiveness Hypothesis: We will focus on parallel analyses for pain and function. We","text_display":"\n\nEffectiveness Hypothesis: We will focus on parallel analyses for pain and function. We","confidence":1,"confidence_rate":1},{"cnt":[[245,872],[1869,872],[1869,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1626,"height":54},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed429df21c374b0397d00a6fbcaaad52","type":"text","conversion_output":true,"text":"hypothesize that SMT alone will decrease average pain by at least 1 point, and average disability","text_display":" hypothesize that SMT alone will decrease average pain by at least 1 point, and average disability","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1800,924],[1800,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1557,"height":51},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f8bac8aa544547c5a66f9c36928a3a9b","type":"text","conversion_output":true,"text":"by 2 points. Similarly, SSM alone will decrease average pain by at least 1 point, and average","text_display":" by 2 points. Similarly, SSM alone will decrease average pain by at least 1 point, and average","confidence":1,"confidence_rate":1},{"cnt":[[245,971],[1745,971],[1745,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1501,"height":50},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f86994f012f7415aa03480d69fa1dafc","type":"text","conversion_output":true,"text":"disability by 2 points, and the combination of SMT+SSM will lead to an sub-additive net","text_display":" disability by 2 points, and the combination of SMT+SSM will lead to an sub-additive net","confidence":0.9990234375,"confidence_rate":0.9999897154250147},{"cnt":[[245,1018],[1070,1018],[1070,1072],[245,1072]],"region":{"top_left_x":244,"top_left_y":1018,"width":826,"height":55},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1866ada812334930b6356e2f71fac6a2","type":"text","conversion_output":true,"text":"decrease of \\(<2\\) points and \\(<4\\) points respectively.","text_display":" decrease of \\(<2\\) points and \\(<4\\) points respectively.","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1833,1113],[1833,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1589,"height":55},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"551f42ce6eec4df09f8865582c69ada9","type":"text","conversion_output":true,"text":"Primary outcome variables: We will derive measure of disability and pain by calculating the","text_display":"\n\nPrimary outcome variables: We will derive measure of disability and pain by calculating the","confidence":0.99951171875,"confidence_rate":0.9999949125077526},{"cnt":[[245,1162],[1841,1162],[1841,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1598,"height":52},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c0df8711a2cf4d52b606c2154323cf3f","type":"text","conversion_output":true,"text":"time-averaged patient outcome using the monthly measurements taken over the year of follow-","text_display":" time-averaged patient outcome using the monthly measurements taken over the year of follow","confidence":1,"confidence_rate":1},{"cnt":[[243,1210],[307,1210],[307,1261],[243,1261]],"region":{"top_left_x":242,"top_left_y":1209,"width":66,"height":53},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"39e0ba8fa2904162a12a9ad796306f0a","type":"text","conversion_output":true,"text":"up.","text_display":"up.","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1798,1306],[1798,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1306,"width":1555,"height":54},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8b7eb02e60514403a0588df2cee09d7e","type":"text","conversion_output":true,"text":"Primary Analysis: For quantitative outcomes we will focus on analyses that generally do not","text_display":"\n\nPrimary Analysis: For quantitative outcomes we will focus on analyses that generally do not","confidence":0.99951171875,"confidence_rate":0.9999949125077526},{"cnt":[[245,1354],[1858,1354],[1858,1405],[245,1405]],"region":{"top_left_x":244,"top_left_y":1353,"width":1615,"height":53},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cb9e69e3eff646178dffca0d03bf9846","type":"text","conversion_output":true,"text":"assume that the effects of SMT and SSM are additive since we have adequate power to evaluate","text_display":" assume that the effects of SMT and SSM are additive since we have adequate power to evaluate","confidence":1,"confidence_rate":1},{"cnt":[[245,1401],[1884,1401],[1884,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1400,"width":1641,"height":55},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4aed2835efd84c029cda71c7ad0b1b40","type":"text","conversion_output":true,"text":"specific group contrasts. We will use linear regression methods with robust standard errors to test","text_display":" specific group contrasts. We will use linear regression methods with robust standard errors to test","confidence":1,"confidence_rate":1},{"cnt":[[245,1450],[1824,1450],[1824,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1450,"width":1581,"height":52},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"78ddad7bb8e54a64af1f239a4c1cb2a7","type":"text","conversion_output":true,"text":"for the difference in mean scores comparing each intervention group to MC. Let \\(Y_{i j}\\) denote the","text_display":" for the difference in mean scores comparing each intervention group to MC. Let \\(Y_{i j}\\) denote the","confidence":0.99951171875,"confidence_rate":0.9999954777833909},{"cnt":[[245,1500],[1820,1500],[1820,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1499,"width":1576,"height":51},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"028da63b34b64cb8a1d58ff85f6dce44","type":"text","conversion_output":true,"text":"outcome of interest (either average pain or average disability for parallel analyses). Similar to","text_display":" outcome of interest (either average pain or average disability for parallel analyses). Similar to","confidence":1,"confidence_rate":1},{"cnt":[[245,1547],[1869,1547],[1869,1601],[245,1601]],"region":{"top_left_x":244,"top_left_y":1546,"width":1626,"height":55},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ff902af0b6044c71b630c22e437fedd1","type":"text","conversion_output":true,"text":"our primary analysis of LBP impact 1 we will use a linear regression model with robust standard","text_display":" our primary analysis of LBP impact 1 we will use a linear regression model with robust standard","confidence":1,"confidence_rate":1},{"cnt":[[245,1594],[683,1594],[683,1646],[245,1646]],"region":{"top_left_x":244,"top_left_y":1594,"width":440,"height":52},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dc6e5d5383534acea2e20ed96ace5669","type":"text","conversion_output":true,"text":"errors using the structure:","text_display":" errors using the structure:","confidence":1,"confidence_rate":1},{"cnt":[[245,1689],[608,1689],[608,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1688,"width":365,"height":55},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1168d7d15f844960b584e02c6102006a","type":"text","conversion_output":true,"text":"Four Groups Model:","text_display":"\n\nFour Groups Model:","confidence":0.99951171875,"confidence_rate":0.9999787654211912},{"cnt":[[610,1684],[1878,1684],[1878,1852],[610,1852]],"region":{"top_left_x":610,"top_left_y":1684,"width":1268,"height":168},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"464ca6532e0c45b8bc9c483d6ffafa7a","type":"math","conversion_output":true,"text":"\\[\n\\begin{aligned}\nE\\left(Y_{i j} \\mid X_{i j}\\right)= & \\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}-\\operatorname{Only} y_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}-\\operatorname{Only} y_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{\\text {-and }-\\operatorname{SSM}_{i j}}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","text_display":"\n\\[\n\\begin{aligned}\nE\\left(Y_{i j} \\mid X_{i j}\\right)= & \\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}-\\operatorname{Only} y_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}-\\operatorname{Only} y_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{\\text {-and }-\\operatorname{SSM}_{i j}}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","confidence":0.22957915303731452,"confidence_rate":0.9951232014307415},{"cnt":[[245,1884],[1293,1884],[1293,1936],[245,1936]],"region":{"top_left_x":244,"top_left_y":1884,"width":1050,"height":52},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a4025aa831fe41bfb97178a31180526e","type":"text","conversion_output":true,"text":"In the primary regression model the parameters of interest are:","text_display":"\n\nIn the primary regression model the parameters of interest are:","confidence":1,"confidence_rate":1},{"cnt":[[367,1934],[1422,1934],[1422,1983],[367,1983]],"region":{"top_left_x":367,"top_left_y":1933,"width":1056,"height":51},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"71e6c123ee824780bd96835ef7df61d3","type":"text","conversion_output":true,"text":"\\(\\beta_{3}=\\) adjusted mean difference comparing SMT Only to UMC;","text_display":"\n\\(\\beta_{3}=\\) adjusted mean difference comparing SMT Only to UMC;","confidence":0.9951171875,"confidence_rate":0.9999258395321943},{"cnt":[[367,1981],[1422,1981],[1422,2035],[367,2035]],"region":{"top_left_x":367,"top_left_y":1980,"width":1056,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0dcd232f9c24479480189a6d97dbe3b6","type":"text","conversion_output":true,"text":"\\(\\beta_{4}=\\) adjusted mean difference comparing SMT Only to UMC;","text_display":"\n\\(\\beta_{4}=\\) adjusted mean difference comparing SMT Only to UMC;","confidence":0.9970703125,"confidence_rate":0.9999555466330077},{"cnt":[[367,2032],[1669,2032],[1669,2084],[367,2084]],"region":{"top_left_x":367,"top_left_y":2032,"width":1303,"height":52},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c0e839fcacba43779cde198cdd0f2f64","type":"text","conversion_output":true,"text":"\\(\\beta_{5}=\\) adjusted mean difference comparing combined SMT and SSM to UMC.","text_display":"\n\\(\\beta_{5}=\\) adjusted mean difference comparing combined SMT and SSM to UMC.","confidence":0.99951171875,"confidence_rate":0.9999937384747559},{"cnt":[[245,2127],[1807,2127],[1807,2176],[245,2176]],"region":{"top_left_x":244,"top_left_y":2126,"width":1563,"height":51},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b7dc17af37f846acb069c0d39a7f1a3c","type":"text","conversion_output":true,"text":"This model considers each treatment group separately using an indicator of SMT only (SMT-","text_display":"\nThis model considers each treatment group separately using an indicator of SMT only (SMT","confidence":1,"confidence_rate":1},{"cnt":[[245,2174],[1818,2174],[1818,2228],[245,2228]],"region":{"top_left_x":244,"top_left_y":2174,"width":1574,"height":54},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3ae7e76596d542ecbd6dc5e7c506847a","type":"text","conversion_output":true,"text":"Only), an indicator of SSM only (SSM-Only), and an indicator of combined therapy with both","text_display":"Only), an indicator of SSM only (SSM-Only), and an indicator of combined therapy with both","confidence":1,"confidence_rate":1},{"cnt":[[245,2221],[1880,2221],[1880,2275],[245,2275]],"region":{"top_left_x":244,"top_left_y":2221,"width":1636,"height":55},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"05e7c974e971430982e9496ef1d762e6","type":"text","conversion_output":true,"text":"SMT and SSM (SMT-and-SSM). We will also add the baseline outcome as a covariate to perform","text_display":" SMT and SSM (SMT-and-SSM). We will also add the baseline outcome as a covariate to perform","confidence":0.9931640625,"confidence_rate":0.9999277982956065},{"cnt":[[245,2271],[1051,2271],[1051,2322],[245,2322]],"region":{"top_left_x":244,"top_left_y":2270,"width":807,"height":53},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"aeb2d3951c2945879a9c8c160f91201c","type":"text","conversion_output":true,"text":"a variation of ANCOVA for repeated measures.","text_display":" a variation of ANCOVA for repeated measures.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":39,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"897bb3e99442464e905c89f2745e5b7d","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 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9.2: Power for the overall F -test of equality of means under","text_display":"","confidence":0.5617372989654541,"confidence_rate":0.9926334086367145},{"cnt":[[262,249],[672,249],[672,288],[262,288]],"region":{"top_left_x":262,"top_left_y":249,"width":411,"height":39},"line":4,"column":1,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0bcd8387865a4a32b762cdcd07ef8ed9","type":"text","conversion_output":false,"parent_id":"8d07fe9189b942459f19251e28b0bd5b","text":"various alternative 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Alternative & \\begin{tabular}{l} \nSMT \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSSM \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSMT \\\\\n\\(+\\) \\\\\nSSM\n\\end{tabular} & Power \\\\\n\\hline Additive & 0.20 & 0.20 & 0.40 & \\(8 8 \\%\\) \\\\\n\\hline Sub-Additive 1 & 0.25 & 0.25 & 0.35 & \\(8 5 \\%\\) \\\\\n\\hline Sub-Additive 2 & 0.30 & 0.30 & 0.30 & \\(8 9 \\%\\) \\\\\n\\hline Sub-Additive 3 & 0.25 & 0.25 & 0.25 & \\(74 \\%\\) \\\\\n\\hline Single effect 1a & 0 & 0.30 & 0.30 & \\(9 6 \\%\\) \\\\\n\\hline Single effect 1b & 0.30 & 0 & 0.30 & \\(8 8 \\%\\) \\\\\n\\hline Single effect 2a & 0 & 0.25 & 0.25 & \\(8 3 \\%\\) \\\\\n\\hline Single effect 2b & 0.25 & 0 & 0.25 & \\(71 \\%\\) \\\\\n\\hline\n\\end{tabular}","text_display":"\n\n\\begin{table}\n\\captionsetup{labelformat=empty}\n\\caption{Table 9.2: Power for the overall F -test of equality of means under various alternative scenarios.}\n\\begin{tabular}{|l|l|l|l|l|}\n\\hline Alternative & \\begin{tabular}{l} \nSMT \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSSM \\\\\nAlone\n\\end{tabular} & \\begin{tabular}{l} \nSMT \\\\\n\\(+\\) \\\\\nSSM\n\\end{tabular} & Power \\\\\n\\hline Additive & 0.20 & 0.20 & 0.40 & \\(8 8 \\%\\) \\\\\n\\hline Sub-Additive 1 & 0.25 & 0.25 & 0.35 & \\(8 5 \\%\\) \\\\\n\\hline Sub-Additive 2 & 0.30 & 0.30 & 0.30 & \\(8 9 \\%\\) \\\\\n\\hline Sub-Additive 3 & 0.25 & 0.25 & 0.25 & \\(74 \\%\\) \\\\\n\\hline Single effect 1a & 0 & 0.30 & 0.30 & \\(9 6 \\%\\) \\\\\n\\hline Single effect 1b & 0.30 & 0 & 0.30 & \\(8 8 \\%\\) \\\\\n\\hline Single effect 2a & 0 & 0.25 & 0.25 & \\(8 3 \\%\\) \\\\\n\\hline Single effect 2b & 0.25 & 0 & 0.25 & \\(71 \\%\\) \\\\\n\\hline\n\\end{tabular}\n\\end{table}","confidence":0.7979506770652249,"confidence_rate":0.9995948603827332},{"cnt":[[1242,301],[1811,301],[1811,350],[1242,350]],"region":{"top_left_x":1241,"top_left_y":300,"width":571,"height":51},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"70b2ca23aef94df8a7747655fa368dc2","type":"text","conversion_output":true,"text":"Our primary analysis will test the","text_display":"\n\nOur primary analysis will test the","confidence":1,"confidence_rate":1},{"cnt":[[1242,348],[1809,348],[1809,397],[1242,397]],"region":{"top_left_x":1241,"top_left_y":348,"width":568,"height":50},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a9a5201a92824880ba729c15657e98b8","type":"text","conversion_output":true,"text":"global hypothesis that these three","text_display":" global hypothesis that these 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provide","confidence":1,"confidence_rate":1},{"cnt":[[1242,924],[1850,924],[1850,969],[1242,969]],"region":{"top_left_x":1241,"top_left_y":923,"width":609,"height":46},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c609389fb76a4504b1d0d40402e06c02","type":"text","conversion_output":true,"text":"individual nominal 95\\% confidence","text_display":" individual nominal 95\\% confidence","confidence":0.99951171875,"confidence_rate":0.9999871474379078},{"cnt":[[245,971],[1366,971],[1366,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1123,"height":50},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9ead84723d0a4b66a4978ef5fed23985","type":"text","conversion_output":true,"text":"intervals and also estimates the simultaneous coverage probability.","text_display":" intervals and also estimates the simultaneous coverage probability.","confidence":1,"confidence_rate":1},{"cnt":[[245,1068],[1717,1068],[1717,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1067,"width":1473,"height":53},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"df6b2a4cb4dd41999f32d143edd90183","type":"text","conversion_output":true,"text":"A secondary evaluation will consider whether the separate effects of SMT and SSM are","text_display":"\n\nA secondary evaluation will consider whether the separate effects of SMT and SSM are","confidence":1,"confidence_rate":1},{"cnt":[[245,1117],[1523,1117],[1523,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1117,"width":1280,"height":50},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"485e419f7f1941f1aeff40ae10e81f90","type":"text","conversion_output":true,"text":"potentially additive, and this will be done using a formal test for interaction:","text_display":" potentially additive, and this will be done using a formal test for interaction:","confidence":1,"confidence_rate":1},{"cnt":[[236,1205],[1639,1205],[1639,1371],[236,1371]],"region":{"top_left_x":236,"top_left_y":1205,"width":1404,"height":166},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"928a302b92ed4258814d533140e4c7d0","type":"math","conversion_output":true,"text":"\\[\n\\text { Interaction Model: } \\quad \\begin{aligned}\nE\\left(Y_{i j} \\mid X_{i j}\\right)= & \\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}{ }_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{i j} \\cdot \\operatorname{SSM}_{i j}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","text_display":"\n\\[\n\\text { Interaction Model: } \\quad \\begin{aligned}\nE\\left(Y_{i j} \\mid X_{i j}\\right)= & \\beta_{0}+\\beta_{1} \\cdot \\operatorname{Site}(2)_{j}+\\beta_{2} \\cdot \\operatorname{RiskGroup}{ }_{i j}+ \\\\\n& \\beta_{3} \\cdot \\operatorname{SMT}_{i j}+\\beta_{4} \\cdot \\operatorname{SSM}_{i j}+\\beta_{5} \\cdot \\operatorname{SMT}_{i j} \\cdot \\operatorname{SSM}_{i j}+ \\\\\n& \\beta_{6} \\cdot \\operatorname{Period}(2)_{i j}+\\beta_{7} \\cdot \\operatorname{Period}(3)_{i j}\n\\end{aligned}\n\\]","confidence":0.7287984981353771,"confidence_rate":0.9989460291719153},{"cnt":[[245,1405],[1865,1405],[1865,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1405,"width":1621,"height":50},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6661677116f940c89e2c0526d8cc193f","type":"text","conversion_output":true,"text":"In this model a test of \\(H 0: \\beta 5=0\\) allows us to determine if there is strong evidence for synergistic","text_display":"\n\nIn this model a test of \\(H 0: \\beta 5=0\\) allows us to determine if there is strong evidence for synergistic","confidence":0.5651288153603673,"confidence_rate":0.9947778885498875},{"cnt":[[245,1452],[1824,1452],[1824,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1452,"width":1581,"height":50},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c2a2e46149a843988ee576948b460f39","type":"text","conversion_output":true,"text":"or antagonistic effects associated with combined treatment. Given that we evaluate interaction","text_display":" or antagonistic effects associated with combined treatment. Given that we evaluate interaction","confidence":1,"confidence_rate":1},{"cnt":[[245,1500],[1566,1500],[1566,1553],[245,1553]],"region":{"top_left_x":244,"top_left_y":1499,"width":1323,"height":55},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"047d0cb656e4434a9148603271c2cb38","type":"text","conversion_output":true,"text":"for both disability and pain we will use a Bonferroni corrected alpha of 0.05/2.","text_display":" for both disability and pain we will use a Bonferroni corrected alpha of 0.05/2.","confidence":0.967937707901001,"confidence_rate":0.9996166905980841},{"cnt":[[245,1598],[1848,1598],[1848,1648],[245,1648]],"region":{"top_left_x":244,"top_left_y":1598,"width":1604,"height":50},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e7a96de5957949b19df764ddb6d45be6","type":"text","conversion_output":true,"text":"Power and Sample Size for primary effectiveness outcomes \\# 2 and \\# 3: See Table 9.2. We will","text_display":"\n\nPower and Sample Size for primary effectiveness outcomes \\# 2 and \\# 3: See Table 9.2. We will","confidence":0.98779296875,"confidence_rate":0.9998771860523339},{"cnt":[[245,1646],[1828,1646],[1828,1695],[245,1695]],"region":{"top_left_x":244,"top_left_y":1645,"width":1585,"height":51},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"85ad04f7ef564c2aa81b121f0c40cdfd","type":"text","conversion_output":true,"text":"conduct longitudinal analysis of the underlying RMDQ and Pain NRS scores. Specifically, we","text_display":" conduct longitudinal analysis of the underlying RMDQ and Pain NRS scores. Specifically, we","confidence":1,"confidence_rate":1},{"cnt":[[245,1693],[1824,1693],[1824,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1692,"width":1581,"height":51},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c2188911f66c46c0a01cf37a20350ccb","type":"text","conversion_output":true,"text":"will conduct analyses using the mean area under the curve for both disability and pain and use","text_display":" will conduct analyses using the mean area under the curve for both disability and pain and use","confidence":1,"confidence_rate":1},{"cnt":[[245,1740],[1781,1740],[1781,1790],[245,1790]],"region":{"top_left_x":244,"top_left_y":1740,"width":1538,"height":50},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"148a628b1de6416f9eef0cdb5d762af5","type":"text","conversion_output":true,"text":"linear regression to evaluate treatment effects on the native underlying scales. With \\(n =1000\\)","text_display":" linear regression to evaluate treatment effects on the native underlying scales. With \\(n =1000\\)","confidence":0.9975602623308077,"confidence_rate":0.9999753263783512},{"cnt":[[245,1788],[1863,1788],[1863,1841],[245,1841]],"region":{"top_left_x":244,"top_left_y":1787,"width":1619,"height":55},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b9c188ac172e411db19a649312dae77e","type":"text","conversion_output":true,"text":"subjects evaluated through one year and using alpha \\(=0.05 / 2\\) for the two outcomes and an overall","text_display":" subjects evaluated through one year and using alpha \\(=0.05 / 2\\) for the two outcomes and an overall","confidence":0.9917149543762207,"confidence_rate":0.9999192308603776},{"cnt":[[245,1835],[1846,1835],[1846,1886],[245,1886]],"region":{"top_left_x":244,"top_left_y":1834,"width":1602,"height":53},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"86098b5c7bb54236a452527d418bdd64","type":"text","conversion_output":true,"text":"F-test we have \\(>80 \\%\\) power across a range of scenarios presented in the table below. To orient","text_display":" F-test we have \\(>80 \\%\\) power across a range of scenarios presented in the table below. To orient","confidence":0.99267578125,"confidence_rate":0.9999272187622368},{"cnt":[[245,1884],[1830,1884],[1830,1936],[245,1936]],"region":{"top_left_x":244,"top_left_y":1884,"width":1587,"height":52},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8f029dc1a932486db5420724a93667d8","type":"text","conversion_output":true,"text":"standardized effects a marginal 2-point mean difference on RMDQ for any treatment modality","text_display":" standardized effects a marginal 2-point mean difference on RMDQ for any treatment modality","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1841,1929],[1841,1983],[245,1983]],"region":{"top_left_x":244,"top_left_y":1929,"width":1598,"height":55},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"67dcb3107dd3499d8beded9e334d8ddc","type":"text","conversion_output":true,"text":"compared to UMC assuming a standard deviation of 6.5 or less, \\({ }^{149153}\\) corresponds to a Cohen's","text_display":" compared to UMC assuming a standard deviation of 6.5 or less, \\({ }^{149153}\\) corresponds to a Cohen's","confidence":0.99951171875,"confidence_rate":0.9999956000051925},{"cnt":[[245,1981],[1760,1981],[1760,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1980,"width":1516,"height":51},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"27c9dabd30c44e299748615627d0e98d","type":"text","conversion_output":true,"text":"D of 2.0/6.5 = 0.31, and \\(>80 \\%\\) power to detect a marginal 1-point difference on Pain NRS","text_display":" D of 2.0/6.5 = 0.31, and \\(>80 \\%\\) power to detect a marginal 1-point difference on Pain NRS","confidence":0.8719233749167188,"confidence_rate":0.9985583692889676},{"cnt":[[245,2024],[1824,2024],[1824,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2023,"width":1581,"height":55},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1e662bcd340745a4939f29882cf2ff57","type":"text","conversion_output":true,"text":"assuming a standard deviation of 3.0 or less corresponds to a standardized effect of \\(0.33 .^{149153}\\)","text_display":" assuming a standard deviation of 3.0 or less corresponds to a standardized effect of \\(0.33 .^{149153}\\)","confidence":0.991228092696872,"confidence_rate":0.9999199067807112},{"cnt":[[245,2075],[1813,2075],[1813,2127],[245,2127]],"region":{"top_left_x":244,"top_left_y":2075,"width":1570,"height":52},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"704c6a592b3f4b3da7a31d3b45f2952e","type":"text","conversion_output":true,"text":"Note that our outcome is the area under the curve through 12 months, which is a patient-level","text_display":" Note that our outcome is the area under the curve through 12 months, which is a patient-level","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[1876,2123],[1876,2176],[245,2176]],"region":{"top_left_x":244,"top_left_y":2122,"width":1632,"height":55},"line":44,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5fd82af05dd24863b53e87bf0f3a2aea","type":"text","conversion_output":true,"text":"weighted average, and the standard deviation (SD) for this outcome will be less than the SD for a","text_display":" weighted average, and the standard deviation (SD) for this outcome will be less than the SD for a","confidence":0.9907269477844238,"confidence_rate":0.9999086677531841},{"cnt":[[245,2172],[1824,2172],[1824,2224],[245,2224]],"region":{"top_left_x":244,"top_left_y":2172,"width":1581,"height":52},"line":45,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"fda495d7ebf24483befc6ceb11714509","type":"text","conversion_output":true,"text":"single measurement. Our power calculations are conservative since we use the SD for a single","text_display":" single measurement. Our power calculations are conservative since we use the SD for a single","confidence":0.98876953125,"confidence_rate":0.99988357372014},{"cnt":[[245,2219],[1846,2219],[1846,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2219,"width":1602,"height":52},"line":46,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d1c27648a0e841e88d4cddb864874dce","type":"text","conversion_output":true,"text":"measurement. Although we have \\(<80 \\%\\) power if SMT and SSM have small marginal effects of","text_display":" measurement. Although we have \\(<80 \\%\\) power if SMT and SSM have small marginal effects of","confidence":0.99951171875,"confidence_rate":0.999994804263518},{"cnt":[[245,2269],[1841,2269],[1841,2318],[245,2318]],"region":{"top_left_x":244,"top_left_y":2268,"width":1598,"height":51},"line":47,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0c2de596dad441888325b2749ca82c5e","type":"text","conversion_output":true,"text":"0.25 SD and no additional benefit when combined (sub-additive 3 below) this scenario leads to","text_display":" 0.25 SD and no additional benefit when combined (sub-additive 3 below) this scenario leads to","confidence":0.9668986797332764,"confidence_rate":0.999670039086755},{"cnt":[[245,2316],[1813,2316],[1813,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2316,"width":1570,"height":50},"line":48,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4f4c920816ad4e25bd7c10b1ea639a29","type":"text","conversion_output":true,"text":"no single treatment arm yielding an effect of 2 points on RMDQ ( 0.31 SD) or 1 point on Pain","text_display":" no single treatment arm yielding an effect of 2 points on RMDQ ( 0.31 SD) or 1 point on Pain","confidence":0.9434406494256109,"confidence_rate":0.999450888356243},{"cnt":[[245,2363],[1781,2363],[1781,2415],[245,2415]],"region":{"top_left_x":244,"top_left_y":2363,"width":1538,"height":52},"line":49,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"102b1f87a75f43bda440131874b72675","type":"text","conversion_output":true,"text":"NRS ( 0.33 SD) and therefore suggests our design is appropriate for important and plausible","text_display":" NRS ( 0.33 SD) and therefore suggests our design is appropriate for important and plausible","confidence":0.750492913041695,"confidence_rate":0.9971049556059214},{"cnt":[[245,2411],[1463,2411],[1463,2464],[245,2464]],"region":{"top_left_x":244,"top_left_y":2410,"width":1220,"height":55},"line":50,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"79dc55d769444aff86b2bd1f188dc56e","type":"text","conversion_output":true,"text":"effect sizes and not overpowered for effects that may not be meaningful.","text_display":" effect sizes and not overpowered for effects that may not be meaningful.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":51,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"9111b666dcb9478285acefe6c9e20a8e","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 67","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-68","page":68,"lines":[{"cnt":[[245,301],[1850,301],[1850,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1606,"height":51},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2b63236316ea4bb181af7411403b7f1c","type":"text","conversion_output":true,"text":"Furthermore, we have excellent power to detect interaction effects where the effect of SMT and","text_display":"\n\nFurthermore, we have excellent power to detect interaction effects where the effect of SMT and","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1850,348],[1850,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1606,"height":50},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"35a56e116fc24a998ef4a3d9ea9d36d3","type":"text","conversion_output":true,"text":"SSM may be synergistic or antagonistic, and using alpha \\(=0.05 / 2\\) we have \\(>80 \\%\\) to detect a 2.7 -","text_display":" SSM may be synergistic or antagonistic, and using alpha \\(=0.05 / 2\\) we have \\(>80 \\%\\) to detect a 2.7 ","confidence":0.9990236759185791,"confidence_rate":0.9999909555872323},{"cnt":[[245,397],[1807,397],[1807,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":1563,"height":53},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"014d377f322f407490fd35b824ed8685","type":"text","conversion_output":true,"text":"point difference in disability or 1.3-point difference in pain treatment effects of one modality","text_display":"point difference in disability or 1.3-point difference in pain treatment effects of one modality","confidence":0.7832406747206733,"confidence_rate":0.9975839604114143},{"cnt":[[245,447],[1201,447],[1201,496],[245,496]],"region":{"top_left_x":244,"top_left_y":446,"width":957,"height":51},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7dcddb4a880f4444b8a6dfd07b75cbc8","type":"text","conversion_output":true,"text":"across the strata defined by the other treatment modality.","text_display":" across the strata defined by the other treatment modality.","confidence":1,"confidence_rate":1},{"cnt":[[236,533],[1704,533],[1704,647],[236,647]],"region":{"top_left_x":236,"top_left_y":532,"width":1468,"height":115},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"862222f76fea433baa80e6babe114ffb","type":"section_header","conversion_output":false,"children_ids":["4981fa63fb5244cf91cf007ea1d5f981","274031ed4c8a42458cc8d0e158c12a3c"],"text":"","text_display":""},{"cnt":[[245,541],[1695,541],[1695,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1452,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4981fa63fb5244cf91cf007ea1d5f981","type":"text","conversion_output":true,"parent_id":"862222f76fea433baa80e6babe114ffb","text":"Secondary Analyses of the 3 primary effectiveness outcomes and other secondary","text_display":"\n\n\\section*{Secondary Analyses of the 3 primary effectiveness outcomes and other secondary","confidence":0.9912109375,"confidence_rate":0.9998973551041204},{"cnt":[[245,589],[1502,589],[1502,642],[245,642]],"region":{"top_left_x":244,"top_left_y":588,"width":1258,"height":55},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"274031ed4c8a42458cc8d0e158c12a3c","type":"text","conversion_output":true,"parent_id":"862222f76fea433baa80e6babe114ffb","text":"outcomes: We will conduct a number of pre-specified secondary analyses.","text_display":" outcomes: We will conduct a number of pre-specified secondary analyses.}","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1863,683],[1863,737],[245,737]],"region":{"top_left_x":244,"top_left_y":683,"width":1619,"height":54},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a240a1be10404ea591b6e9d6e5405d01","type":"text","conversion_output":true,"text":"Subgroup/Moderator Analyses: We will consider two pre-specified subgroup analyses to look at","text_display":"\n\nSubgroup/Moderator Analyses: We will consider two pre-specified subgroup analyses to look at","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1850,730],[1850,784],[245,784]],"region":{"top_left_x":244,"top_left_y":730,"width":1606,"height":55},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"74b57542affe4b17b18927777f8dac44","type":"text","conversion_output":true,"text":"treatment effects within: subjects who are medium risk based on STarT Back, and subjects who","text_display":" treatment effects within: subjects who are medium risk based on STarT Back, and subjects who","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1852,778],[1852,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":1608,"height":55},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"47a3cdce6e544e47b1b8587c91cbd109","type":"text","conversion_output":true,"text":"are high risk; and subjects stratified based on their duration of LBP. Subgroup analyses will use","text_display":" are high risk; and subjects stratified based on their duration of LBP. Subgroup analyses will use","confidence":1,"confidence_rate":1},{"cnt":[[245,827],[1835,827],[1835,879],[245,879]],"region":{"top_left_x":244,"top_left_y":827,"width":1591,"height":52},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bb03bc84e60d4d1ea4895ac0b46a974e","type":"text","conversion_output":true,"text":"logistic or linear regression among restricted subsets to quantify specific treatment effects, and","text_display":" logistic or linear regression among restricted subsets to quantify specific treatment effects, and","confidence":1,"confidence_rate":1},{"cnt":[[245,872],[1830,872],[1830,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1587,"height":54},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bc8f66b0625942c3a6e614ed6ce2bda1","type":"text","conversion_output":true,"text":"formal evaluation of differences in treatment effects across subgroups will be conducted using","text_display":" formal evaluation of differences in treatment effects across subgroups will be conducted using","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1824,924],[1824,975],[245,975]],"region":{"top_left_x":244,"top_left_y":923,"width":1581,"height":53},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9deb6affb924405b9451665ccfdf3c83","type":"text","conversion_output":true,"text":"treatment by subgroup interactions. In addition to the pre-specified subgroup analyses we will","text_display":" treatment by subgroup interactions. In addition to the pre-specified subgroup analyses we will","confidence":1,"confidence_rate":1},{"cnt":[[245,971],[1863,971],[1863,1023],[245,1023]],"region":{"top_left_x":244,"top_left_y":971,"width":1619,"height":52},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6562d58508b04e6f92629f8240ff5229","type":"text","conversion_output":true,"text":"also conduct exploratory analyses to evaluate the heterogeneity of treatment effects according to","text_display":" also conduct exploratory analyses to evaluate the heterogeneity of treatment effects according to","confidence":1,"confidence_rate":1},{"cnt":[[245,1018],[735,1018],[735,1072],[245,1072]],"region":{"top_left_x":244,"top_left_y":1018,"width":491,"height":55},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cead964b89294775a76eacd120b1a1f6","type":"text","conversion_output":true,"text":"Gender, Race, and Ethnicity.","text_display":" Gender, Race, and Ethnicity.","confidence":1,"confidence_rate":1},{"cnt":[[245,1113],[1820,1113],[1820,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1576,"height":55},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0dd74719fbc94bffbec8d7a2afb343f4","type":"text","conversion_output":true,"text":"Responder Analysis: We will focus on evaluation of a \\(>50 \\%\\) improvement in pain or function","text_display":"\n\nResponder Analysis: We will focus on evaluation of a \\(>50 \\%\\) improvement in pain or function","confidence":0.9975602623308077,"confidence_rate":0.9999748176502898},{"cnt":[[245,1162],[1757,1162],[1757,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1514,"height":52},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"920bfff88f024df989b917a26d8c78f7","type":"text","conversion_output":true,"text":"from baseline to six months, and from baseline to one year. We will also consider a \\(>30 \\%\\)","text_display":" from baseline to six months, and from baseline to one year. We will also consider a \\(>30 \\%\\)","confidence":0.99560546875,"confidence_rate":0.9999521292373095},{"cnt":[[245,1212],[1882,1212],[1882,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1211,"width":1639,"height":51},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8737737a799843b2bd0ae055111fb913","type":"text","conversion_output":true,"text":"improvement, and a comprehensive responder analysis that looks at the cumulative percentage of","text_display":" improvement, and a comprehensive responder analysis that looks at the cumulative percentage of","confidence":1,"confidence_rate":1},{"cnt":[[245,1259],[1785,1259],[1785,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1258,"width":1542,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cb5c892cb71f4f1d9ea645f7a2313b7b","type":"text","conversion_output":true,"text":"subject achieving a range of improvement percentages as described in Farrar, Dworkin, and","text_display":" subject achieving a range of improvement percentages as described in Farrar, Dworkin, and","confidence":1,"confidence_rate":1},{"cnt":[[245,1302],[372,1302],[372,1351],[245,1351]],"region":{"top_left_x":244,"top_left_y":1301,"width":128,"height":51},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"24dd09a999c64dfe98ebb3e46cc21da6","type":"text","conversion_output":true,"text":"Max. \\({ }^{76}\\)","text_display":" Max. \\({ }^{76}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1401],[1858,1401],[1858,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1400,"width":1615,"height":55},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"90586912bb04419c89ebda80feb0e871","type":"text","conversion_output":true,"text":"Secondary Outcomes: We will assess secondary outcomes including the PROMIS-29 measure,","text_display":"\n\nSecondary Outcomes: We will assess secondary outcomes including the PROMIS-29 measure,","confidence":1,"confidence_rate":1},{"cnt":[[245,1450],[1764,1450],[1764,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1450,"width":1520,"height":52},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0d5cadea80d04e869138317494756d28","type":"text","conversion_output":true,"text":"productivity loss, healthcare utilization (e.g., opioid use, injection, MRIs), and AEs for the","text_display":" productivity loss, healthcare utilization (e.g., opioid use, injection, MRIs), and AEs for the","confidence":1,"confidence_rate":1},{"cnt":[[245,1500],[1854,1500],[1854,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1499,"width":1611,"height":51},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"187c0b379b864468b209e64aa610bf7e","type":"text","conversion_output":true,"text":"combined group (SMT+SSM) and each intervention alone relative to MC. We will use linear or","text_display":" combined group (SMT+SSM) and each intervention alone relative to MC. We will use linear or","confidence":0.9638671875,"confidence_rate":0.9996126880123871},{"cnt":[[245,1543],[1815,1543],[1815,1596],[245,1596]],"region":{"top_left_x":244,"top_left_y":1542,"width":1572,"height":55},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"faec43a8ca5b4799825e4cdf555f3613","type":"text","conversion_output":true,"text":"logistic regression and the Four Group model structure given above and will use linear mixed","text_display":" logistic regression and the Four Group model structure given above and will use linear mixed","confidence":1,"confidence_rate":1},{"cnt":[[245,1594],[1738,1594],[1738,1646],[245,1646]],"region":{"top_left_x":244,"top_left_y":1594,"width":1495,"height":52},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"143ef932381a488b8bea26d86322abd2","type":"text","conversion_output":true,"text":"models or generalized estimating equations (GEE) for longitudinal analysis of secondary","text_display":" models or generalized estimating equations (GEE) for longitudinal analysis of secondary","confidence":1,"confidence_rate":1},{"cnt":[[245,1637],[471,1637],[471,1687],[245,1687]],"region":{"top_left_x":244,"top_left_y":1637,"width":227,"height":50},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"478ec12982434d2db3f4685c8130ed46","type":"text","conversion_output":true,"text":"outcomes. \\({ }^{154}\\)","text_display":" outcomes. \\({ }^{154}\\)","confidence":0.99951171875,"confidence_rate":0.9999796501863057},{"cnt":[[245,1738],[1785,1738],[1785,1790],[245,1790]],"region":{"top_left_x":244,"top_left_y":1738,"width":1542,"height":52},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0980cd61c2634fff8e28462a83d00d44","type":"text","conversion_output":true,"text":"Time-until-recovery: An important class of secondary analyses will consider the time-until-","text_display":"\n\nTime-until-recovery: An important class of secondary analyses will consider the time-until","confidence":1,"confidence_rate":1},{"cnt":[[245,1783],[1869,1783],[1869,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1783,"width":1626,"height":54},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"45a8df45a8f34c0294fb6b463d78572d","type":"text","conversion_output":true,"text":"recovery based on measurements taken every 4 weeks during the year of follow-up. Specifically,","text_display":"recovery based on measurements taken every 4 weeks during the year of follow-up. Specifically,","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1766,1835],[1766,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1523,"height":51},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ce027ee575b6464d87eb4f6c1c5dd93a","type":"text","conversion_output":true,"text":"we can define the time-until-recovery as the assessment month in which the subject is first","text_display":" we can define the time-until-recovery as the assessment month in which the subject is first","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1768,1882],[1768,1934],[245,1934]],"region":{"top_left_x":244,"top_left_y":1882,"width":1525,"height":52},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5183d2a16c4f4e30b5fef5fba720012d","type":"text","conversion_output":true,"text":"observed to achieve an NRS \\(=0\\) and RMDQ \\(<=2\\). We will use discrete time (monthly data)","text_display":" observed to achieve an NRS \\(=0\\) and RMDQ \\(<=2\\). We will use discrete time (monthly data)","confidence":0.9990234375,"confidence_rate":0.999989822555459},{"cnt":[[245,1929],[1833,1929],[1833,1981],[245,1981]],"region":{"top_left_x":244,"top_left_y":1929,"width":1589,"height":52},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"caa5983e265b4b3e9c8980c192e96ac4","type":"text","conversion_output":true,"text":"cumulative incidence curves to show the percent of subjects in each treatment group who have","text_display":" cumulative incidence curves to show the percent of subjects in each treatment group who have","confidence":1,"confidence_rate":1},{"cnt":[[245,1977],[1858,1977],[1858,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1976,"width":1615,"height":55},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a2e5f99e636d4e03bd5928a6f2a377fc","type":"text","conversion_output":true,"text":"achieved a first recovery by each follow-up time period. We recognize that recovery may not be","text_display":" achieved a first recovery by each follow-up time period. We recognize that recovery may not be","confidence":1,"confidence_rate":1},{"cnt":[[245,2024],[1800,2024],[1800,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2023,"width":1557,"height":55},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e97c9474f07b4309b1e6b52248d1d1c0","type":"text","conversion_output":true,"text":"maintained, and subjects may subsequently relapse so we will also display plots showing the","text_display":" maintained, and subjects may subsequently relapse so we will also display plots showing the","confidence":1,"confidence_rate":1},{"cnt":[[245,2073],[1732,2073],[1732,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2073,"width":1488,"height":52},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"52839d55f2684b7cbf610f9763d6a9fc","type":"text","conversion_output":true,"text":"percent of subjects who are currently in the recovered state as a function of time. Formal","text_display":" percent of subjects who are currently in the recovered state as a function of time. Formal","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[1841,2123],[1841,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2122,"width":1598,"height":51},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2d851eb3d0b44ed192221fa2460c6f06","type":"text","conversion_output":true,"text":"comparison of cumulative incidence curves can be obtained using the log rank test since in this","text_display":" comparison of cumulative incidence curves can be obtained using the log rank test since in this","confidence":1,"confidence_rate":1},{"cnt":[[245,2170],[1798,2170],[1798,2219],[245,2219]],"region":{"top_left_x":244,"top_left_y":2169,"width":1555,"height":51},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a493b8dea0d946be8ec7e178a296411a","type":"text","conversion_output":true,"text":"situation the cumulative incidence is simply 1 -survival as would be computed using Kaplan-","text_display":" situation the cumulative incidence is simply 1 -survival as would be computed using Kaplan","confidence":0.99951171875,"confidence_rate":0.9999950666738041},{"cnt":[[245,2217],[1437,2217],[1437,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2217,"width":1194,"height":54},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"478e83e89e4644be91df8f6301956e43","type":"text","conversion_output":true,"text":"Meier curves. In addition, we will use a model-based survival analysis.","text_display":"Meier curves. In addition, we will use a model-based survival analysis.","confidence":0.9990236759185791,"confidence_rate":0.9999871474379078},{"cnt":[[245,2312],[1880,2312],[1880,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2311,"width":1636,"height":55},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"44bf0537a0a6479aa8ee1b474aad689c","type":"text","conversion_output":true,"text":"Cross-sectional outcomes at 2, 6 , and 12 months: We will also conduct analysis of change in pain","text_display":"\n\nCross-sectional outcomes at 2, 6 , and 12 months: We will also conduct analysis of change in pain","confidence":0.8620909270830452,"confidence_rate":0.9986269201118199},{"cnt":[[245,2361],[1837,2361],[1837,2413],[245,2413]],"region":{"top_left_x":244,"top_left_y":2361,"width":1593,"height":52},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"84501bf5356f4afb92aa464f92a583d6","type":"text","conversion_output":true,"text":"NRS, RMDQ, and STarT Back status from baseline. Satisfaction will also be analyzed at these","text_display":" NRS, RMDQ, and STarT Back status from baseline. Satisfaction will also be analyzed at these","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":40,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"b39fd4b8298a43cdbaa04080cd8d654e","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 68","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-69","page":69,"lines":[{"cnt":[[245,249],[1880,249],[1880,303],[245,303]],"region":{"top_left_x":244,"top_left_y":249,"width":1636,"height":54},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2e7cc4e1d2b246d7bfd198a5c1d07a6c","type":"text","conversion_output":true,"text":"time points. This analysis will evaluate the magnitude of short, medium, and long-term effects of","text_display":"\ntime points. This analysis will evaluate the magnitude of short, medium, and long-term effects of","confidence":1,"confidence_rate":1},{"cnt":[[245,301],[1592,301],[1592,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1348,"height":51},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"50232aee756d4f7ba48f584e1cbf1ab2","type":"text","conversion_output":true,"text":"treatment, which are traditionally used in systematic reviews and meta-analyses.","text_display":" treatment, which are traditionally used in systematic reviews and meta-analyses.","confidence":1,"confidence_rate":1},{"cnt":[[243,391],[1800,391],[1800,449],[243,449]],"region":{"top_left_x":242,"top_left_y":391,"width":1559,"height":59},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8287e89ab45b45f8a8da3d6ccbb87b1e","type":"text","conversion_output":true,"text":"Mediation Analysis for Psychosocial Factors: Formal mediation analysis \\({ }^{155-157}\\) will focus on","text_display":"\n\nMediation Analysis for Psychosocial Factors: Formal mediation analysis \\({ }^{155-157}\\) will focus on","confidence":1,"confidence_rate":1},{"cnt":[[245,443],[1865,443],[1865,496],[245,496]],"region":{"top_left_x":244,"top_left_y":442,"width":1621,"height":55},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2174b6a71d8f48999b79bdbfd51ac15e","type":"text","conversion_output":true,"text":"characterizing the degree to which self-efficacy, coping, kinesiophobia, and pain catastrophizing","text_display":" characterizing the degree to which self-efficacy, coping, kinesiophobia, and pain catastrophizing","confidence":1,"confidence_rate":1},{"cnt":[[245,494],[1785,494],[1785,544],[245,544]],"region":{"top_left_x":244,"top_left_y":494,"width":1542,"height":50},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"819a94a0ee4344ddbc602020488bd721","type":"text","conversion_output":true,"text":"measured at 8 weeks can explain treatment effects at 6 months, and whether these measures","text_display":" measured at 8 weeks can explain treatment effects at 6 months, and whether these measures","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1841,541],[1841,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1598,"height":50},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"49ecbefb91a14a4094e02e53e754cc58","type":"text","conversion_output":true,"text":"obtained at 6 months explain long-term treatment effects ( 1 year). We will quantify the percent","text_display":" obtained at 6 months explain long-term treatment effects ( 1 year). We will quantify the percent","confidence":0.998535871389322,"confidence_rate":0.9999863066218455},{"cnt":[[245,589],[1794,589],[1794,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1550,"height":51},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed2a358a0deb4d1a971482439cc9ab1c","type":"text","conversion_output":true,"text":"of the treatment effect that is explained by changes in each scale individually, and in totality","text_display":" of the treatment effect that is explained by changes in each scale individually, and in totality","confidence":1,"confidence_rate":1},{"cnt":[[245,632],[1858,632],[1858,690],[245,690]],"region":{"top_left_x":244,"top_left_y":631,"width":1615,"height":59},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"83cbc559f647410c9d7de67541befa35","type":"text","conversion_output":true,"text":"when included in a multivariate model for the outcome. \\({ }^{158}\\) We will analyze mediation for cLBP,","text_display":" when included in a multivariate model for the outcome. \\({ }^{158}\\) We will analyze mediation for cLBP,","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1824,683],[1824,737],[245,737]],"region":{"top_left_x":244,"top_left_y":683,"width":1581,"height":54},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"83f05258e9a94c2e86ce8741aef811ec","type":"text","conversion_output":true,"text":"recovery at six months and change in pain NRS and RMDQ measured at 6 months and 1 year.","text_display":" recovery at six months and change in pain NRS and RMDQ measured at 6 months and 1 year.","confidence":1,"confidence_rate":1},{"cnt":[[243,778],[1798,778],[1798,831],[243,831]],"region":{"top_left_x":242,"top_left_y":777,"width":1557,"height":55},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"75cf2832643742f1bb5f84e6141bab8b","type":"text","conversion_output":true,"text":"Longitudinal analyses of patient trajectories for pain and disability: We will use the monthly","text_display":"\n\nLongitudinal analyses of patient trajectories for pain and disability: We will use the monthly","confidence":1,"confidence_rate":1},{"cnt":[[245,827],[1734,827],[1734,879],[245,879]],"region":{"top_left_x":244,"top_left_y":827,"width":1490,"height":52},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c3a1d851117c49ae9097d4139758eaf4","type":"text","conversion_output":true,"text":"measures of disability and weekly measures of pain to conduct longitudinal analysis that","text_display":" measures of disability and weekly measures of pain to conduct longitudinal analysis that","confidence":1,"confidence_rate":1},{"cnt":[[245,872],[1790,872],[1790,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1546,"height":54},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6e65f9a57e96485aa34789d544033597","type":"text","conversion_output":true,"text":"characterizes the mean profile over time for each intervention group. Formal comparison of","text_display":" characterizes the mean profile over time for each intervention group. Formal comparison of","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1871,924],[1871,975],[245,975]],"region":{"top_left_x":244,"top_left_y":923,"width":1628,"height":53},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"96c1a276adae4fe1ac5fa2bedce269ff","type":"text","conversion_output":true,"text":"profiles will be based on linear mixed models or GEE. Furthermore, we will conduct exploratory","text_display":" profiles will be based on linear mixed models or GEE. Furthermore, we will conduct exploratory","confidence":1,"confidence_rate":1},{"cnt":[[245,971],[1798,971],[1798,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1555,"height":50},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4d8ec302478544b0a759d0a7fd10226f","type":"text","conversion_output":true,"text":"analyses that assume latent classes with associated trajectories, and we can evaluate whether","text_display":" analyses that assume latent classes with associated trajectories, and we can evaluate whether","confidence":1,"confidence_rate":1},{"cnt":[[245,1014],[1798,1014],[1798,1070],[245,1070]],"region":{"top_left_x":244,"top_left_y":1014,"width":1555,"height":56},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"30de25fc836546aca2a626cad01cd876","type":"text","conversion_output":true,"text":"these groups differ across the intervention arms. \\({ }^{159}\\) We have recently used these methods for","text_display":" these groups differ across the intervention arms. \\({ }^{159}\\) We have recently used these methods for","confidence":1,"confidence_rate":1},{"cnt":[[245,1061],[965,1061],[965,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1061,"width":721,"height":59},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b457fd0571844128b62df6f17d80eef9","type":"text","conversion_output":true,"text":"analysis of the BOLD back pain cohort. \\({ }^{160}\\)","text_display":" analysis of the BOLD back pain cohort. \\({ }^{160}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,1160],[1876,1160],[1876,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1160,"width":1632,"height":54},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9d900f90de2148dca34d81129736f161","type":"text","conversion_output":true,"text":"Longitudinal Analysis Adjusting for Concomitant/Subsequent Therapy: Our first analysis will be","text_display":"\n\nLongitudinal Analysis Adjusting for Concomitant/Subsequent Therapy: Our first analysis will be","confidence":1,"confidence_rate":1},{"cnt":[[245,1212],[1841,1212],[1841,1263],[245,1263]],"region":{"top_left_x":244,"top_left_y":1211,"width":1598,"height":53},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"02eb9fbef21748d4851bcf785b486dfd","type":"text","conversion_output":true,"text":"a descriptive summary of the types and frequency of additional treatments received throughout","text_display":" a descriptive summary of the types and frequency of additional treatments received throughout","confidence":1,"confidence_rate":1},{"cnt":[[245,1259],[1798,1259],[1798,1308],[245,1308]],"region":{"top_left_x":244,"top_left_y":1258,"width":1555,"height":51},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0b30d769c492447e9b13e93673e399d0","type":"text","conversion_output":true,"text":"the study. The initial study intervention occurs within the first two months and outcomes are","text_display":" the study. The initial study intervention occurs within the first two months and outcomes are","confidence":1,"confidence_rate":1},{"cnt":[[245,1306],[1826,1306],[1826,1360],[245,1360]],"region":{"top_left_x":244,"top_left_y":1306,"width":1583,"height":54},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0713152788c948878c4a6d67f5300c25","type":"text","conversion_output":true,"text":"collected through one year. Therefore, there is potential for variation in the treatment received","text_display":" collected through one year. Therefore, there is potential for variation in the treatment received","confidence":1,"confidence_rate":1},{"cnt":[[245,1354],[1800,1354],[1800,1407],[245,1407]],"region":{"top_left_x":244,"top_left_y":1353,"width":1557,"height":55},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b4a9d98753f94599a07e74d4a915dcff","type":"text","conversion_output":true,"text":"according to randomized group or non-study interventions during months \\(3-12\\). Intermediate","text_display":" according to randomized group or non-study interventions during months \\(3-12\\). Intermediate","confidence":0.8516347408294678,"confidence_rate":0.9983625914876469},{"cnt":[[245,1401],[1858,1401],[1858,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1400,"width":1615,"height":55},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"44d2658980c64048b9dd18189a1f8946","type":"text","conversion_output":true,"text":"treatment received is a post-randomization variable and potential intermediate outcome that will","text_display":" treatment received is a post-randomization variable and potential intermediate outcome that will","confidence":1,"confidence_rate":1},{"cnt":[[245,1450],[1775,1450],[1775,1500],[245,1500]],"region":{"top_left_x":244,"top_left_y":1450,"width":1531,"height":50},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ed0d2805b38c4ea1bed15c92f8ccbf99","type":"text","conversion_output":true,"text":"be considered in mediation analysis. In addition, we can use structural nested mean models","text_display":" be considered in mediation analysis. In addition, we can use structural nested mean models","confidence":1,"confidence_rate":1},{"cnt":[[245,1495],[1871,1495],[1871,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1495,"width":1628,"height":55},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1ba9732ae9cf4e6bbcd5c7b1a0eaae25","type":"text","conversion_output":true,"text":"(SNMMs) or marginal structural models \\({ }^{161}{ }^{162}\\) to adjust for time-varying confounding (treatment","text_display":" (SNMMs) or marginal structural models \\({ }^{161}{ }^{162}\\) to adjust for time-varying confounding (treatment","confidence":0.9824931621551514,"confidence_rate":0.9998477538759498},{"cnt":[[245,1547],[1800,1547],[1800,1596],[245,1596]],"region":{"top_left_x":244,"top_left_y":1546,"width":1557,"height":51},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"46ec3c67602347e8936519d0078a9d25","type":"text","conversion_output":true,"text":"contamination) associated with intermediate treatment received. For example, if we consider","text_display":" contamination) associated with intermediate treatment received. For example, if we consider","confidence":1,"confidence_rate":1},{"cnt":[[245,1594],[1772,1594],[1772,1646],[245,1646]],"region":{"top_left_x":244,"top_left_y":1594,"width":1529,"height":52},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b98decf562a541f3b3b9e91f421ef3e4","type":"text","conversion_output":true,"text":"longitudinal concomitant treatment \\(a _{ k }\\), measured at times \\(k =1,2, \\ldots, m\\), then using SNMM","text_display":" longitudinal concomitant treatment \\(a _{ k }\\), measured at times \\(k =1,2, \\ldots, m\\), then using SNMM","confidence":0.998046875,"confidence_rate":0.9999829998415843},{"cnt":[[245,1641],[1830,1641],[1830,1695],[245,1695]],"region":{"top_left_x":244,"top_left_y":1641,"width":1587,"height":55},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0a08e990b65b403988cd50b8600ec88b","type":"text","conversion_output":true,"text":"notation we can define the 1 -year counterfactual outcome for subject i as \\(Yi ( Z , al , a 2, \\ldots, am )\\)","text_display":" notation we can define the 1 -year counterfactual outcome for subject i as \\(Yi ( Z , al , a 2, \\ldots, am )\\)","confidence":0.5558480094495567,"confidence_rate":0.9948164864426594},{"cnt":[[245,1693],[1826,1693],[1826,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1692,"width":1583,"height":51},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bcc219e9ebb74c879983d060aaa4ece2","type":"text","conversion_output":true,"text":"which represents the potential outcome associated with baseline treatment Z and time-varying","text_display":" which represents the potential outcome associated with baseline treatment Z and time-varying","confidence":0.9926877021789551,"confidence_rate":0.9999287485218227},{"cnt":[[245,1740],[1772,1740],[1772,1790],[245,1790]],"region":{"top_left_x":244,"top_left_y":1740,"width":1529,"height":50},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c8b976e9b0854bf38a305a7d7287bce2","type":"text","conversion_output":true,"text":"concomitant treatments. We can use either SNMMs or MSMs to estimate population mean","text_display":" concomitant treatments. We can use either SNMMs or MSMs to estimate population mean","confidence":1,"confidence_rate":1},{"cnt":[[245,1783],[1772,1783],[1772,1837],[245,1837]],"region":{"top_left_x":244,"top_left_y":1783,"width":1529,"height":54},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dfa0b08767084e1596f55985aa6edfba","type":"text","conversion_output":true,"text":"outcomes under controlled concomitant treatment paths such as the expected outcome with","text_display":" outcomes under controlled concomitant treatment paths such as the expected outcome with","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1772,1835],[1772,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1529,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5d4b0c61f23246d180c538db213dc8fe","type":"text","conversion_output":true,"text":"treatment Z and no additional longitudinal treatments: mean of \\(Yi ( Z , 0,0, \\ldots, 0)\\). For these","text_display":" treatment Z and no additional longitudinal treatments: mean of \\(Yi ( Z , 0,0, \\ldots, 0)\\). For these","confidence":0.9941503966692835,"confidence_rate":0.9999456794450937},{"cnt":[[245,1882],[1850,1882],[1850,1931],[245,1931]],"region":{"top_left_x":244,"top_left_y":1882,"width":1606,"height":50},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cf762ece8d63490387084f14a8afe898","type":"text","conversion_output":true,"text":"longitudinal analyses we will use the monthly measured RMDQ and Pain NRS as the outcomes","text_display":" longitudinal analyses we will use the monthly measured RMDQ and Pain NRS as the outcomes","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1738,1929],[1738,1981],[245,1981]],"region":{"top_left_x":244,"top_left_y":1929,"width":1495,"height":52},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0943f208733645ae8136608d49b245cd","type":"text","conversion_output":true,"text":"in parallel regression analyses. We have previously conducted critical evaluation of such","text_display":" in parallel regression analyses. We have previously conducted critical evaluation of such","confidence":1,"confidence_rate":1},{"cnt":[[245,1972],[1182,1972],[1182,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1972,"width":938,"height":59},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b1c27d42847e4ef88055c41b3fde34fa","type":"text","conversion_output":true,"text":"methods for the analysis of surgical non-compliance. \\({ }^{163}\\)","text_display":" methods for the analysis of surgical non-compliance. \\({ }^{163}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,2071],[1880,2071],[1880,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2071,"width":1636,"height":54},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a9da6f5bdc07483583c3d43987f8c4ee","type":"text","conversion_output":true,"text":"Impact of cLBP \\& recovery definitions: The robustness of NIH RTF case definition of cLBP will","text_display":"\n\nImpact of cLBP \\& recovery definitions: The robustness of NIH RTF case definition of cLBP will","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[1712,2123],[1712,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2122,"width":1469,"height":51},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"32923ee817df4d3a98e0918969e1bd0f","type":"text","conversion_output":true,"text":"be assessed using measures of pain frequency and LBP-related burden (pain, disability,","text_display":" be assessed using measures of pain frequency and LBP-related burden (pain, disability,","confidence":1,"confidence_rate":1},{"cnt":[[245,2170],[1833,2170],[1833,2219],[245,2219]],"region":{"top_left_x":244,"top_left_y":2169,"width":1589,"height":51},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9dc08a9aea594f9b8f129cdff77f591e","type":"text","conversion_output":true,"text":"productivity loss, healthcare utilization) by assessing differences between subjects meeting the","text_display":" productivity loss, healthcare utilization) by assessing differences between subjects meeting the","confidence":1,"confidence_rate":1},{"cnt":[[245,2217],[1729,2217],[1729,2271],[245,2271]],"region":{"top_left_x":244,"top_left_y":2217,"width":1486,"height":54},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b2c66ee7da4441dbabc45df5f2f92b9e","type":"text","conversion_output":true,"text":"case definition and those who do not. We will also explore the clinical and demographic","text_display":" case definition and those who do not. We will also explore the clinical and demographic","confidence":1,"confidence_rate":1},{"cnt":[[245,2264],[1852,2264],[1852,2316],[245,2316]],"region":{"top_left_x":244,"top_left_y":2264,"width":1608,"height":53},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"11a24b29f8704c50a88dcb024ec7e158","type":"text","conversion_output":true,"text":"characteristics of subjects with high LBP-related burden who fail to meet the case definition for","text_display":" characteristics of subjects with high LBP-related burden who fail to meet the case definition for","confidence":1,"confidence_rate":1},{"cnt":[[245,2312],[1818,2312],[1818,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2311,"width":1574,"height":55},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6fd8be8ff98b4f50a06c28d8404a2e9f","type":"text","conversion_output":true,"text":"cLBP in addition to the characteristics of subjects with low LBP-related burden who meet the","text_display":" cLBP in addition to the characteristics of subjects with low LBP-related burden who meet the","confidence":1,"confidence_rate":1},{"cnt":[[245,2361],[1850,2361],[1850,2413],[245,2413]],"region":{"top_left_x":244,"top_left_y":2361,"width":1606,"height":52},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8292fb36fc5c4990a53870a3078ee0ca","type":"text","conversion_output":true,"text":"case definition for cLBP. We will also assess the impact of an alternative definition of recovery","text_display":" case definition for cLBP. We will also assess the impact of an alternative definition of recovery","confidence":1,"confidence_rate":1},{"cnt":[[245,2408],[1437,2408],[1437,2460],[245,2460]],"region":{"top_left_x":244,"top_left_y":2408,"width":1194,"height":52},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6f7280ea24844635bc369bcb86b97f47","type":"text","conversion_output":true,"text":"(e.g., NRS \\(<2\\) and RMDQ \\(<3\\) ) on treatment effects at 6 and 12 months.","text_display":" (e.g., NRS \\(<2\\) and RMDQ \\(<3\\) ) on treatment effects at 6 and 12 months.","confidence":0.5138633474707603,"confidence_rate":0.9921976807639836},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"3d4e8477f7de4c55b3fa36f640005ce1","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 69","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-70","page":70,"lines":[{"cnt":[[245,301],[1880,301],[1880,350],[245,350]],"region":{"top_left_x":244,"top_left_y":300,"width":1636,"height":51},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"84e444f7c3b44240a2ef9bc9899fd0de","type":"text","conversion_output":true,"text":"Sample Size for Seconday Objective of Implementation: Qualitative data collection associated","text_display":"\n\nSample Size for Seconday Objective of Implementation: Qualitative data collection associated","confidence":1,"confidence_rate":1},{"cnt":[[245,348],[1837,348],[1837,397],[245,397]],"region":{"top_left_x":244,"top_left_y":348,"width":1593,"height":50},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ec9be50124f04913ac383e53d84a0fe4","type":"text","conversion_output":true,"text":"with Aim 2 will require a minimum of \\(22-30\\) participants from each of the patient, facility, and","text_display":" with Aim 2 will require a minimum of \\(22-30\\) participants from each of the patient, facility, and","confidence":0.958984375,"confidence_rate":0.9996049790107305},{"cnt":[[245,397],[1863,397],[1863,449],[245,449]],"region":{"top_left_x":244,"top_left_y":397,"width":1619,"height":53},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4d4b8a51cc224fc3b1db41f6b5ce5349","type":"text","conversion_output":true,"text":"organizational levels; this is the approximate number to reach 'saturation', or the point where no","text_display":" organizational levels; this is the approximate number to reach 'saturation', or the point where no","confidence":1,"confidence_rate":1},{"cnt":[[245,440],[690,440],[690,494],[245,494]],"region":{"top_left_x":244,"top_left_y":440,"width":446,"height":55},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"93ceeaba629b4c9b922597db1c338adb","type":"text","conversion_output":true,"text":"new themes emerge. \\({ }^{164165}\\)","text_display":" new themes emerge. \\({ }^{164165}\\)","confidence":0.9970703125,"confidence_rate":0.99991850367004},{"cnt":[[245,541],[1863,541],[1863,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1619,"height":50},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"45b1f21413444d0baac6d57115d07301","type":"text","conversion_output":true,"text":"Analysis plan for Implementation: Qualitative and quantitative analyses will be performed for","text_display":"\n\nAnalysis plan for Implementation: Qualitative and quantitative analyses will be performed for","confidence":1,"confidence_rate":1},{"cnt":[[245,589],[1772,589],[1772,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1529,"height":51},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"34896507bbe642d697123de6da2ff4c3","type":"text","conversion_output":true,"text":"data collected regarding contextual information that will inform future implementation and","text_display":" data collected regarding contextual information that will inform future implementation and","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1768,636],[1768,690],[245,690]],"region":{"top_left_x":244,"top_left_y":635,"width":1525,"height":55},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"33d48e698e0d494f8ba8093b022785a0","type":"text","conversion_output":true,"text":"results interpretation, as described in Section 6.2.6. Qualitative data will be analyzed using","text_display":" results interpretation, as described in Section 6.2.6. Qualitative data will be analyzed using","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1785,683],[1785,735],[245,735]],"region":{"top_left_x":244,"top_left_y":683,"width":1542,"height":52},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"bf4f76e53b594f69a4e6df013f1ddf11","type":"text","conversion_output":true,"text":"template style qualitative content analysis using NVivo qualitative software or similar. Data","text_display":" template style qualitative content analysis using NVivo qualitative software or similar. Data","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1669,730],[1669,780],[245,780]],"region":{"top_left_x":244,"top_left_y":730,"width":1426,"height":50},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c5c9517b78954d699032837dcd0b8005","type":"text","conversion_output":true,"text":"collection and analyses will be performed by clinical site investigators and designees","text_display":" collection and analyses will be performed by clinical site investigators and designees","confidence":1,"confidence_rate":1},{"cnt":[[245,776],[1880,776],[1880,831],[245,831]],"region":{"top_left_x":244,"top_left_y":775,"width":1636,"height":57},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"972a50d3a50f41f4a1262f4259ce49f0","type":"text","conversion_output":true,"text":"experienced in analysis of qualitative data using methods applied previously. \\({ }^{166-169}\\) All qualitative","text_display":" experienced in analysis of qualitative data using methods applied previously. \\({ }^{166-169}\\) All qualitative","confidence":1,"confidence_rate":1},{"cnt":[[245,829],[1876,829],[1876,879],[245,879]],"region":{"top_left_x":244,"top_left_y":829,"width":1632,"height":50},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c5a8454374d24571aaf465db12fa2e20","type":"text","conversion_output":true,"text":"analyses will begin with the creation of a working codebook, developed by reviewing samples of","text_display":" analyses will begin with the creation of a working codebook, developed by reviewing samples of","confidence":1,"confidence_rate":1},{"cnt":[[245,872],[1740,872],[1740,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1497,"height":54},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3c6b2f33ea4c4add82958d683bbb4dee","type":"text","conversion_output":true,"text":"texts to gain a general understanding of the data and establish preliminary codes. \\({ }^{164165168}\\)","text_display":" texts to gain a general understanding of the data and establish preliminary codes. \\({ }^{164165168}\\)","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1796,924],[1796,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1553,"height":51},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"3d74283039e74b27b2a51a1f2a866db4","type":"text","conversion_output":true,"text":"Representative quotations will be identified during the coding process; coded themes will be","text_display":" Representative quotations will be identified during the coding process; coded themes will be","confidence":0.99951171875,"confidence_rate":0.9999949649559944},{"cnt":[[245,971],[1854,971],[1854,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1611,"height":50},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2257611734844d6ca4ed7b091e8182fa","type":"text","conversion_output":true,"text":"grouped into larger thematic categories. Themes will then be quantified by categorizing them as","text_display":" grouped into larger thematic categories. Themes will then be quantified by categorizing them as","confidence":1,"confidence_rate":1},{"cnt":[[245,1016],[1762,1016],[1762,1072],[245,1072]],"region":{"top_left_x":244,"top_left_y":1016,"width":1518,"height":57},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e2f168ac94dc42d29dbf1d1360469689","type":"text","conversion_output":true,"text":"present or absent for each case, and presented as frequencies. \\({ }^{164}\\) The DCC will oversee the","text_display":" present or absent for each case, and presented as frequencies. \\({ }^{164}\\) The DCC will oversee the","confidence":1,"confidence_rate":1},{"cnt":[[245,1068],[1704,1068],[1704,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1067,"width":1460,"height":53},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"06524ede9cf04044bd31a9fb4c8cb6a1","type":"text","conversion_output":true,"text":"conduct of validity checks of \\(10 \\%\\) of the analyzed cases to ensure consistency with the","text_display":" conduct of validity checks of \\(10 \\%\\) of the analyzed cases to ensure consistency with the","confidence":0.994140625,"confidence_rate":0.999937484842569},{"cnt":[[245,1113],[1785,1113],[1785,1167],[245,1167]],"region":{"top_left_x":244,"top_left_y":1112,"width":1542,"height":55},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7d93cba5609b4201a84e13e7d7801587","type":"text","conversion_output":true,"text":"codebook. Quantitative analyses will be performed by the DCC and will include descriptive","text_display":" codebook. Quantitative analyses will be performed by the DCC and will include descriptive","confidence":1,"confidence_rate":1},{"cnt":[[245,1164],[1854,1164],[1854,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1164,"width":1611,"height":50},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"28429f22d30e41a38742704cfe90cf54","type":"text","conversion_output":true,"text":"statistics data collected as described in Section 6.2.6. Independent t-tests (for means) and z-tests","text_display":" statistics data collected as described in Section 6.2.6. Independent t-tests (for means) and z-tests","confidence":0.5903692245483398,"confidence_rate":0.9949934591565965},{"cnt":[[245,1212],[1515,1212],[1515,1263],[245,1263]],"region":{"top_left_x":244,"top_left_y":1211,"width":1271,"height":53},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"17ed222f14be42f3a1c0343425435b86","type":"text","conversion_output":true,"text":"(for proportions) will be used to assess group differences when appropriate.","text_display":" (for proportions) will be used to assess group differences when appropriate.","confidence":1,"confidence_rate":1},{"cnt":[[236,1302],[941,1302],[941,1364],[236,1364]],"region":{"top_left_x":236,"top_left_y":1301,"width":706,"height":64},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e458a5762dc24560bd7e54c28880e697","type":"section_header","conversion_output":false,"children_ids":["26c76fcdd8a34838810c4e5e636f27eb"],"text":"","text_display":""},{"cnt":[[245,1359],[245,1306],[935,1308],[935,1361]],"region":{"top_left_x":244,"top_left_y":1306,"width":691,"height":55},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"26c76fcdd8a34838810c4e5e636f27eb","type":"text","conversion_output":true,"parent_id":"e458a5762dc24560bd7e54c28880e697","text":"General Missing Data Considerations:","text_display":"\n\n\\section*{General Missing Data Considerations:}","confidence":1,"confidence_rate":1},{"cnt":[[245,1354],[1747,1354],[1747,1405],[245,1405]],"region":{"top_left_x":244,"top_left_y":1353,"width":1503,"height":53},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5dc0902bcc1b45f6b420654057140277","type":"text","conversion_output":true,"text":"Missing data may include missing covariate information, study dropout, or missed and/or","text_display":"\n\nMissing data may include missing covariate information, study dropout, or missed and/or","confidence":1,"confidence_rate":1},{"cnt":[[245,1403],[1807,1403],[1807,1454],[245,1454]],"region":{"top_left_x":244,"top_left_y":1402,"width":1563,"height":53},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c34607427d4642389f91e00ffabdcb5f","type":"text","conversion_output":true,"text":"mistimed participant visits. While the PACBACK protocol includes procedures to ensure the","text_display":" mistimed participant visits. While the PACBACK protocol includes procedures to ensure the","confidence":0.98681640625,"confidence_rate":0.9998588262557832},{"cnt":[[245,1452],[1846,1452],[1846,1502],[245,1502]],"region":{"top_left_x":244,"top_left_y":1452,"width":1602,"height":50},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d526c0dd43d24db8a5c5e3edc393f9c3","type":"text","conversion_output":true,"text":"most \"complete\" follow-up data on every enrolled participant, it is likely that some participants","text_display":" most \"complete\" follow-up data on every enrolled participant, it is likely that some participants","confidence":1,"confidence_rate":1},{"cnt":[[245,1500],[1712,1500],[1712,1549],[245,1549]],"region":{"top_left_x":244,"top_left_y":1499,"width":1469,"height":51},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"667b8f43c1f6425e9ec4d63d861f42c2","type":"text","conversion_output":true,"text":"will have incomplete data. We will determine reasons for missingness, classifying each","text_display":" will have incomplete data. We will determine reasons for missingness, classifying each","confidence":1,"confidence_rate":1},{"cnt":[[245,1547],[1824,1547],[1824,1596],[245,1596]],"region":{"top_left_x":244,"top_left_y":1546,"width":1581,"height":51},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"22ebb8236d474c0fad7accc4a1010ef7","type":"text","conversion_output":true,"text":"missingness pattern as missing completely at random (MCAR), missing at random (MAR), or","text_display":" missingness pattern as missing completely at random (MCAR), missing at random (MAR), or","confidence":1,"confidence_rate":1},{"cnt":[[245,1594],[1738,1594],[1738,1644],[245,1644]],"region":{"top_left_x":244,"top_left_y":1594,"width":1495,"height":50},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7d3506208162441a956ad333583230af","type":"text","conversion_output":true,"text":"missing not at random (MNAR). The MCAR mechanism occurs when the probability of","text_display":" missing not at random (MNAR). The MCAR mechanism occurs when the probability of","confidence":1,"confidence_rate":1},{"cnt":[[245,1637],[1858,1637],[1858,1693],[245,1693]],"region":{"top_left_x":244,"top_left_y":1637,"width":1615,"height":56},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"94c9a5f55722498bbdf190b10a077edc","type":"text","conversion_output":true,"text":"response is independent of both the observed data and the unobserved data \\({ }^{170}\\). All protocols will","text_display":" response is independent of both the observed data and the unobserved data \\({ }^{170}\\). All protocols will","confidence":1,"confidence_rate":1},{"cnt":[[245,1691],[1854,1691],[1854,1742],[245,1742]],"region":{"top_left_x":244,"top_left_y":1690,"width":1611,"height":53},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"913a1908b528470fa461eb2ab0010816","type":"text","conversion_output":true,"text":"include recommended sensitivity analyses that will help determine the extent of potential biases","text_display":" include recommended sensitivity analyses that will help determine the extent of potential biases","confidence":1,"confidence_rate":1},{"cnt":[[245,1738],[715,1738],[715,1785],[245,1785]],"region":{"top_left_x":244,"top_left_y":1738,"width":472,"height":48},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7c542e103e3841119baf11cf1540f4d8","type":"text","conversion_output":true,"text":"that could affect the results.","text_display":" that could affect the results.","confidence":1,"confidence_rate":1},{"cnt":[[245,1835],[1830,1835],[1830,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1834,"width":1587,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9cfe5f3d2f104f62a7f8f38d8779fb60","type":"text","conversion_output":true,"text":"In longitudinal analyses, likelihood-based analyses of complete-case data for the linear mixed-","text_display":"\n\nIn longitudinal analyses, likelihood-based analyses of complete-case data for the linear mixed","confidence":1,"confidence_rate":1},{"cnt":[[245,1882],[1880,1882],[1880,1931],[245,1931]],"region":{"top_left_x":244,"top_left_y":1882,"width":1636,"height":50},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2676e0fe7ea7470bbe1c977f68a442c1","type":"text","conversion_output":true,"text":"effects model, the generalized linear mixed-effects model, and the nonlinear mixed-effects model","text_display":"effects model, the generalized linear mixed-effects model, and the nonlinear mixed-effects model","confidence":1,"confidence_rate":1},{"cnt":[[245,1929],[1843,1929],[1843,1979],[245,1979]],"region":{"top_left_x":244,"top_left_y":1929,"width":1600,"height":50},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"557c5b2233b14ad3a70de77990b8da9e","type":"text","conversion_output":true,"text":"lead to valid inference under MCAR and MAR mechanisms, whereas the GEE analyses lead to","text_display":" lead to valid inference under MCAR and MAR mechanisms, whereas the GEE analyses lead to","confidence":1,"confidence_rate":1},{"cnt":[[245,1972],[1824,1972],[1824,2030],[245,2030]],"region":{"top_left_x":244,"top_left_y":1972,"width":1581,"height":59},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d9867affb6644331a395b90089c93768","type":"text","conversion_output":true,"text":"valid inference only in the presence of MCAR mechanisms. \\({ }^{170}{ }^{171}\\) Statistical tests to assess the","text_display":" valid inference only in the presence of MCAR mechanisms. \\({ }^{170}{ }^{171}\\) Statistical tests to assess the","confidence":0.7857942581176758,"confidence_rate":0.9979417767878709},{"cnt":[[245,2024],[1807,2024],[1807,2075],[245,2075]],"region":{"top_left_x":244,"top_left_y":2023,"width":1563,"height":53},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8ea12c2367d4483eae69af5ba0ee9eac","type":"text","conversion_output":true,"text":"validity of the MCAR assumption in certain circumstances are available, but they are model-","text_display":" validity of the MCAR assumption in certain circumstances are available, but they are model","confidence":1,"confidence_rate":1},{"cnt":[[245,2071],[1790,2071],[1790,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2071,"width":1546,"height":54},"line":36,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b1612988568148ba917b711e90380085","type":"text","conversion_output":true,"text":"dependent and non-robust. \\({ }^{172-174}\\) In general, we will advocate the use of multiple imputation","text_display":"dependent and non-robust. \\({ }^{172-174}\\) In general, we will advocate the use of multiple imputation","confidence":1,"confidence_rate":1},{"cnt":[[245,2118],[1818,2118],[1818,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2118,"width":1574,"height":55},"line":37,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a9d39cbe44444e7dbb507826ca9d13df","type":"text","conversion_output":true,"text":"(MI) \\({ }^{175}\\) both to assess the sensitivity of results and to correct for bias from missing covariates.","text_display":" (MI) \\({ }^{175}\\) both to assess the sensitivity of results and to correct for bias from missing covariates.","confidence":0.99365234375,"confidence_rate":0.9999441428909199},{"cnt":[[245,2170],[1727,2170],[1727,2219],[245,2219]],"region":{"top_left_x":244,"top_left_y":2169,"width":1484,"height":51},"line":38,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2766cf3cdda246ad8d495da3e7a90472","type":"text","conversion_output":true,"text":"We will consider the missing data mechanism, analysis approach, and plausibility of the","text_display":" We will consider the missing data mechanism, analysis approach, and plausibility of the","confidence":0.9970703125,"confidence_rate":0.9999681093407484},{"cnt":[[245,2213],[1846,2213],[1846,2267],[245,2267]],"region":{"top_left_x":244,"top_left_y":2212,"width":1602,"height":55},"line":39,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"05f1459462c64cba9c10b8ad4a5bfdb1","type":"text","conversion_output":true,"text":"congeniality assumption. \\({ }^{176}{ }^{177}\\) If MNAR data are suspected, there are three basic approaches to","text_display":" congeniality assumption. \\({ }^{176}{ }^{177}\\) If MNAR data are suspected, there are three basic approaches to","confidence":0.9887909889221191,"confidence_rate":0.9999036601498247},{"cnt":[[245,2260],[1848,2260],[1848,2314],[245,2314]],"region":{"top_left_x":244,"top_left_y":2260,"width":1604,"height":54},"line":40,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"81b7ea344c7c4df1813237117d5f4295","type":"text","conversion_output":true,"text":"address this challenge, namely, (1) selection models \\({ }^{178-180}\\), (2) pattern-mixture models \\({ }^{181182}\\) and","text_display":" address this challenge, namely, (1) selection models \\({ }^{178-180}\\), (2) pattern-mixture models \\({ }^{181182}\\) and","confidence":0.8974609375,"confidence_rate":0.9991348889585683},{"cnt":[[245,2307],[1835,2307],[1835,2365],[245,2365]],"region":{"top_left_x":244,"top_left_y":2307,"width":1591,"height":59},"line":41,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ee6c1db7deff4512b338eff259303c47","type":"text","conversion_output":true,"text":"(3) MI. \\({ }^{175}{ }^{183}\\) We recommend MI because it appears to be more robust. We can apply MI using","text_display":" (3) MI. \\({ }^{175}{ }^{183}\\) We recommend MI because it appears to be more robust. We can apply MI using","confidence":0.99951171875,"confidence_rate":0.9999956392907748},{"cnt":[[245,2363],[1848,2363],[1848,2413],[245,2413]],"region":{"top_left_x":244,"top_left_y":2363,"width":1604,"height":50},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"4f65881117bd471e80d3d65f380324c6","type":"text","conversion_output":true,"text":"weights dependent on the probability of dropout to assess the dependence of results on dropout.","text_display":" weights dependent on the probability of dropout to assess the dependence of results on dropout.","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1880,2582],[1880,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":377,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"d9e0b514dbd84a66a18cc3c69bd6252f","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 70","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-71","page":71,"lines":[{"cnt":[[245,254],[1687,254],[1687,303],[245,303]],"region":{"top_left_x":244,"top_left_y":253,"width":1443,"height":50},"line":1,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a39967073510488a9031f0e0213d192f","type":"text","conversion_output":true,"text":"We will also consider selection models with varying dropout parameters in sensitivity","text_display":"\n\nWe will also consider selection models with varying dropout parameters in sensitivity","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[496,296],[496,350],[245,350]],"region":{"top_left_x":244,"top_left_y":296,"width":253,"height":55},"line":2,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"20cc7f610daa4560a75e8e11e33d0ad3","type":"text","conversion_output":true,"text":"analyses. \\({ }^{183} 184\\)","text_display":" analyses. \\({ }^{183} 184\\)","confidence":0.9428987503051758,"confidence_rate":0.9978247259420708},{"cnt":[[241,391],[1055,391],[1055,449],[241,449]],"region":{"top_left_x":240,"top_left_y":391,"width":815,"height":59},"line":3,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ce69d4fc98ce44d9b1560063a3bf29e4","type":"section_header","conversion_output":false,"children_ids":["c0c2cf74cc954f4a82f0aaa627454874"],"text":"","text_display":""},{"cnt":[[245,397],[1051,397],[1051,445],[245,445]],"region":{"top_left_x":244,"top_left_y":397,"width":807,"height":48},"line":4,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c0c2cf74cc954f4a82f0aaa627454874","type":"text","conversion_output":true,"parent_id":"ce69d4fc98ce44d9b1560063a3bf29e4","text":"Potential Problems \\& Alternative Strategies:","text_display":"\n\n\\section*{Potential Problems \\& Alternative Strategies:}","confidence":0.9990234375,"confidence_rate":0.9999800606141427},{"cnt":[[245,443],[1820,443],[1820,494],[245,494]],"region":{"top_left_x":244,"top_left_y":442,"width":1576,"height":53},"line":5,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"44b6f348f0b640f7a6e0654b70117d21","type":"text","conversion_output":true,"text":"Factorial Model Assumptions: We have assumed both an additive data-generating model with","text_display":"\n\nFactorial Model Assumptions: We have assumed both an additive data-generating model with","confidence":1,"confidence_rate":1},{"cnt":[[245,492],[1833,492],[1833,544],[245,544]],"region":{"top_left_x":244,"top_left_y":491,"width":1589,"height":53},"line":6,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"7f3c242c75774cc4bfb8e6d9cac01f93","type":"text","conversion_output":true,"text":"small effects and alternative sub-additive scenarios with moderate effects for the three primary","text_display":" small effects and alternative sub-additive scenarios with moderate effects for the three primary","confidence":1,"confidence_rate":1},{"cnt":[[245,541],[1798,541],[1798,591],[245,591]],"region":{"top_left_x":244,"top_left_y":541,"width":1555,"height":50},"line":7,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"0c484666109842fc9cd0381379cb464b","type":"text","conversion_output":true,"text":"effectiveness outcomes. However, for the secondary binary outcomes and we have assumed","text_display":" effectiveness outcomes. However, for the secondary binary outcomes and we have assumed","confidence":1,"confidence_rate":1},{"cnt":[[245,589],[1858,589],[1858,638],[245,638]],"region":{"top_left_x":244,"top_left_y":588,"width":1615,"height":51},"line":8,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"c81db83d96ac4e53a00d88375d5fe3cb","type":"text","conversion_output":true,"text":"additivity to assess power for SMT and SSM treatment main effects. For these binary outcomes","text_display":" additivity to assess power for SMT and SSM treatment main effects. For these binary outcomes","confidence":1,"confidence_rate":1},{"cnt":[[245,636],[1871,636],[1871,685],[245,685]],"region":{"top_left_x":244,"top_left_y":635,"width":1628,"height":51},"line":9,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b67820210db344f3919117af9cc4b021","type":"text","conversion_output":true,"text":"it is possible that there is an interaction that is either synergistic or antagonistic (sub-additive). In","text_display":" it is possible that there is an interaction that is either synergistic or antagonistic (sub-additive). In","confidence":1,"confidence_rate":1},{"cnt":[[245,683],[1749,683],[1749,735],[245,735]],"region":{"top_left_x":244,"top_left_y":683,"width":1505,"height":52},"line":10,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"8f331e32bcb74304bcc2c983de84a11d","type":"text","conversion_output":true,"text":"this situation our proposed analysis will estimate an average treatment effect rather than a","text_display":" this situation our proposed analysis will estimate an average treatment effect rather than a","confidence":1,"confidence_rate":1},{"cnt":[[245,730],[1807,730],[1807,782],[245,782]],"region":{"top_left_x":244,"top_left_y":730,"width":1563,"height":53},"line":11,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a4cc08076bac44b7bfb3ba63ac06e1d9","type":"text","conversion_output":true,"text":"common treatment effect. A synergistic interaction however would suggest that SMT + SSM","text_display":" common treatment effect. A synergistic interaction however would suggest that SMT + SSM","confidence":1,"confidence_rate":1},{"cnt":[[245,778],[1837,778],[1837,831],[245,831]],"region":{"top_left_x":244,"top_left_y":777,"width":1593,"height":55},"line":12,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2ccbb82124004a7fa73dc4c7c6b77005","type":"text","conversion_output":true,"text":"produce greater effects together, than when used alone. Conversely, an antagonistic interaction","text_display":" produce greater effects together, than when used alone. Conversely, an antagonistic interaction","confidence":1,"confidence_rate":1},{"cnt":[[245,829],[1807,829],[1807,879],[245,879]],"region":{"top_left_x":244,"top_left_y":829,"width":1563,"height":50},"line":13,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d5aaee9b491649f383e330273d1296e7","type":"text","conversion_output":true,"text":"would suggest that their effects are less than additive. Both scenarios would provide new and","text_display":" would suggest that their effects are less than additive. Both scenarios would provide new and","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[245,872],[1863,872],[1863,926],[245,926]],"region":{"top_left_x":244,"top_left_y":872,"width":1619,"height":54},"line":14,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"538fba5a310e414ebf50b2576be0391e","type":"text","conversion_output":true,"text":"important information and advance what is known about these therapies and how they should be","text_display":" important information and advance what is known about these therapies and how they should be","confidence":1,"confidence_rate":1},{"cnt":[[245,924],[1811,924],[1811,973],[245,973]],"region":{"top_left_x":244,"top_left_y":923,"width":1568,"height":51},"line":15,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f9d7bc35bd6746f4973b9a2ccdb3326a","type":"text","conversion_output":true,"text":"applied for acute and sub-acute LBP. Importantly, even if an interaction is observed, we have","text_display":" applied for acute and sub-acute LBP. Importantly, even if an interaction is observed, we have","confidence":1,"confidence_rate":1},{"cnt":[[245,971],[1803,971],[1803,1021],[245,1021]],"region":{"top_left_x":244,"top_left_y":971,"width":1559,"height":50},"line":16,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f067c69c21724571a41aac1a79e10100","type":"text","conversion_output":true,"text":">80\\% power to detect the following differences between the combined group or either of the","text_display":" >80\\% power to detect the following differences between the combined group or either of the","confidence":0.9785258769989014,"confidence_rate":0.9997715203484326},{"cnt":[[245,1018],[1809,1018],[1809,1070],[245,1070]],"region":{"top_left_x":244,"top_left_y":1018,"width":1565,"height":52},"line":17,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e028aa33ee5f4f9fa0ade0826b6ef798","type":"text","conversion_output":true,"text":"single interventions alone compared to medical care: For prevention of chronicity, we will be","text_display":" single interventions alone compared to medical care: For prevention of chronicity, we will be","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[245,1066],[1772,1066],[1772,1119],[245,1119]],"region":{"top_left_x":244,"top_left_y":1065,"width":1529,"height":55},"line":18,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"2eaa3c1520c54eb8a5f2f4885a8b8d3e","type":"text","conversion_output":true,"text":"powered to detect a reduction of \\(9 \\%( RR =0.55)\\) at an event rate of \\(20 \\%\\) in the MC group, a","text_display":" powered to detect a reduction of \\(9 \\%( RR =0.55)\\) at an event rate of \\(20 \\%\\) in the MC group, a","confidence":0.998046875,"confidence_rate":0.9999806434067887},{"cnt":[[245,1113],[1807,1113],[1807,1164],[245,1164]],"region":{"top_left_x":244,"top_left_y":1112,"width":1563,"height":53},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"888818522a7c43b7bd40156f20191cfe","type":"text","conversion_output":true,"text":"reduction of \\(11 \\%(R R=0.63)\\) if the event rate is \\(30 \\%\\), and a reduction of \\(12 \\%(R R=0.7)\\) if the","text_display":" reduction of \\(11 \\%(R R=0.63)\\) if the event rate is \\(30 \\%\\), and a reduction of \\(12 \\%(R R=0.7)\\) if the","confidence":0.903901792713441,"confidence_rate":0.9990289855776924},{"cnt":[[245,1162],[1848,1162],[1848,1214],[245,1214]],"region":{"top_left_x":244,"top_left_y":1162,"width":1604,"height":52},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"6d64c84fef9f4a52b211581c82ee2070","type":"text","conversion_output":true,"text":"event rate is \\(40 \\%\\). For recovery, we will be powered to detect an increase of \\(7 \\%( RR =2.4)\\) at an","text_display":" event rate is \\(40 \\%\\). For recovery, we will be powered to detect an increase of \\(7 \\%( RR =2.4)\\) at an","confidence":0.5539286136627197,"confidence_rate":0.9945453065621467},{"cnt":[[245,1210],[1858,1210],[1858,1261],[245,1261]],"region":{"top_left_x":244,"top_left_y":1209,"width":1615,"height":53},"line":21,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"60027bf08c1d48baa2fa762fc917ceb0","type":"text","conversion_output":true,"text":"event rate of \\(5 \\%\\) in the MC group, \\(9 \\%(R R=1.9)\\) if the event rate is \\(10 \\%\\), and \\(10 \\%(R R=1.67)\\) if","text_display":" event rate of \\(5 \\%\\) in the MC group, \\(9 \\%(R R=1.9)\\) if the event rate is \\(10 \\%\\), and \\(10 \\%(R R=1.67)\\) if","confidence":0.8165847819764167,"confidence_rate":0.9981256057630107},{"cnt":[[245,1259],[612,1259],[612,1304],[245,1304]],"region":{"top_left_x":244,"top_left_y":1258,"width":369,"height":47},"line":22,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"174f190e77614086b109bd3f606cf647","type":"text","conversion_output":true,"text":"the event rate is \\(15 \\%\\).","text_display":" the event rate is \\(15 \\%\\).","confidence":1,"confidence_rate":1},{"cnt":[[243,1414],[1302,1414],[1302,1470],[243,1470]],"region":{"top_left_x":242,"top_left_y":1413,"width":1060,"height":57},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"a415805d02a146f19b26ceccb63b131e","type":"section_header","conversion_output":false,"children_ids":["304726142eef4f49bf526ada95bbcf51"],"text":"","text_display":""},{"cnt":[[249,1418],[1300,1418],[1300,1465],[249,1465]],"region":{"top_left_x":249,"top_left_y":1417,"width":1051,"height":49},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"304726142eef4f49bf526ada95bbcf51","type":"text","conversion_output":true,"parent_id":"a415805d02a146f19b26ceccb63b131e","text":"10. DATA COLLECTION AND QUALITY ASSURANCE","text_display":"\n\n\\section*{10. DATA COLLECTION AND QUALITY ASSURANCE}","confidence":1,"confidence_rate":1},{"cnt":[[305,1504],[846,1504],[846,1553],[305,1553]],"region":{"top_left_x":305,"top_left_y":1503,"width":542,"height":51},"line":25,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"e716c40cadf7486ea098459ec516b0b9","type":"section_header","conversion_output":false,"children_ids":["aad282de436e465ea89e931ab9e23ca6"],"text":"","text_display":""},{"cnt":[[309,1508],[844,1508],[844,1549],[309,1549]],"region":{"top_left_x":309,"top_left_y":1508,"width":536,"height":42},"line":26,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"aad282de436e465ea89e931ab9e23ca6","type":"text","conversion_output":true,"parent_id":"e716c40cadf7486ea098459ec516b0b9","text":"10.1 Data Collection Forms","text_display":"\n\n\\subsection*{10.1 Data Collection Forms}","confidence":1,"confidence_rate":1},{"cnt":[[245,1575],[1777,1575],[1777,1622],[245,1622]],"region":{"top_left_x":244,"top_left_y":1574,"width":1533,"height":49},"line":27,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5ef5a1c97ebf45dd912178b9c587151d","type":"text","conversion_output":true,"text":"Initial screening data will be directly entered by potential study participants via a web-based survey","text_display":"\n\nInitial screening data will be directly entered by potential study participants via a web-based survey","confidence":1,"confidence_rate":1},{"cnt":[[245,1620],[1745,1620],[1745,1665],[245,1665]],"region":{"top_left_x":244,"top_left_y":1619,"width":1501,"height":47},"line":28,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"5141c0c1336c4ed48bea1a07a4b07bf5","type":"text","conversion_output":true,"text":"supplied by the DCC. Phone-based screening data and in-person/video-conference screening data","text_display":" supplied by the DCC. Phone-based screening data and in-person/video-conference screening data","confidence":1,"confidence_rate":1},{"cnt":[[245,1663],[1837,1663],[1837,1710],[245,1710]],"region":{"top_left_x":244,"top_left_y":1662,"width":1593,"height":49},"line":29,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"125ec87d400547059d39d304da6aa0af","type":"text","conversion_output":true,"text":"obtained at the in-person/videoconference visit will be entered directly into the study portal by research","text_display":" obtained at the in-person/videoconference visit will be entered directly into the study portal by research","confidence":1,"confidence_rate":1},{"cnt":[[245,1706],[1785,1706],[1785,1755],[245,1755]],"region":{"top_left_x":244,"top_left_y":1705,"width":1542,"height":51},"line":30,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1666a62d9e804eeab23697eb106c696c","type":"text","conversion_output":true,"text":"staff at the sites to confirm study eligibility. For consented participants, protected health and contact","text_display":" staff at the sites to confirm study eligibility. For consented participants, protected health and contact","confidence":1,"confidence_rate":1},{"cnt":[[245,1749],[1846,1749],[1846,1798],[245,1798]],"region":{"top_left_x":244,"top_left_y":1748,"width":1602,"height":51},"line":31,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"52ab1307dff6486686f21c3d217afd32","type":"text","conversion_output":true,"text":"information will be stored in a separate limited-access REDCap database and no research personnel will","text_display":" information will be stored in a separate limited-access REDCap database and no research personnel will","confidence":0.99951171875,"confidence_rate":0.9999954355197808},{"cnt":[[245,1796],[1828,1796],[1828,1841],[245,1841]],"region":{"top_left_x":244,"top_left_y":1796,"width":1585,"height":46},"line":32,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9db730f4ad40491abb1d5d4a4bf36f83","type":"text","conversion_output":true,"text":"have data export rights in this database. Data collected as a part of the research study protocol database","text_display":" have data export rights in this database. Data collected as a part of the research study protocol database","confidence":1,"confidence_rate":1},{"cnt":[[245,1839],[1833,1839],[1833,1884],[245,1884]],"region":{"top_left_x":244,"top_left_y":1839,"width":1589,"height":46},"line":33,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"1616f21e9b4b4aec9c2d76ae870c8007","type":"text","conversion_output":true,"text":"will be stored in a completely separate database, linked by study ID. A procedure/visit case report form","text_display":" will be stored in a completely separate database, linked by study ID. A procedure/visit case report form","confidence":0.9990236759185791,"confidence_rate":0.9999910385631244},{"cnt":[[245,1882],[1858,1882],[1858,1929],[245,1929]],"region":{"top_left_x":244,"top_left_y":1882,"width":1615,"height":48},"line":34,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"38bff5641ea543d1afd89a5c55b588a3","type":"text","conversion_output":true,"text":"will be filled out by research staff for every study-related visit and electronically entered directly into the","text_display":" will be filled out by research staff for every study-related visit and electronically entered directly into the","confidence":1,"confidence_rate":1},{"cnt":[[245,1925],[1803,1925],[1803,1972],[245,1972]],"region":{"top_left_x":244,"top_left_y":1925,"width":1559,"height":48},"line":35,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"dcf70dbc09a5481c93468542bc81b71f","type":"text","conversion_output":true,"text":"web-based portal. Electronic web-based surveys will be sent to study participants on a monthly basis,","text_display":" web-based portal. 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Printable CRFs will be made available for every study","text_display":" cases where follow-up may be challenging. 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The UWA DCC will support","text_display":"\n\nData management in the LBP project will be almost exclusively web-based. The UWA DCC will support","confidence":1,"confidence_rate":1},{"cnt":[[245,2256],[1762,2256],[1762,2305],[245,2305]],"region":{"top_left_x":244,"top_left_y":2255,"width":1518,"height":51},"line":42,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"f16d154767a4464b88579d91955874bc","type":"text","conversion_output":true,"text":"an https-secured web page (www.PACBACK.ORG) that provides a centralized location for public","text_display":" an https-secured web page (www.PACBACK.ORG) that provides a centralized location for public","confidence":0.9990234375,"confidence_rate":0.999989822555459},{"cnt":[[245,2299],[1807,2299],[1807,2348],[245,2348]],"region":{"top_left_x":244,"top_left_y":2298,"width":1563,"height":51},"line":43,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"06ffec6928af4ac7b7afe6fd8b3656c4","type":"text","conversion_output":true,"text":"information about the project for potential subjects, investigators, and institutional agencies. The web","text_display":" information about the project for potential subjects, investigators, and institutional agencies. The web","confidence":1,"confidence_rate":1},{"cnt":[[245,2344],[1871,2344],[1871,2391],[245,2391]],"region":{"top_left_x":244,"top_left_y":2343,"width":1628,"height":49},"line":44,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d9eea6c77a9d48e1a1640adae984894d","type":"text","conversion_output":true,"text":"page will contain a link to the project portal. Study personnel will log on to the private portal on the study","text_display":" page will contain a link to the project portal. Study personnel will log on to the private portal on the study","confidence":0.78271484375,"confidence_rate":0.9978719472300666},{"cnt":[[245,2389],[1807,2389],[1807,2434],[245,2434]],"region":{"top_left_x":244,"top_left_y":2389,"width":1563,"height":46},"line":45,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"9cc20bb37b8e403e99a74eec1d8d4ff9","type":"text","conversion_output":true,"text":"web page with individual Shibboleth-based user names and passwords to securely perform study data","text_display":" web page with individual Shibboleth-based user names and passwords to securely perform study data","confidence":1,"confidence_rate":1},{"cnt":[[245,2432],[1807,2432],[1807,2479],[245,2479]],"region":{"top_left_x":244,"top_left_y":2432,"width":1563,"height":48},"line":46,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"cdf02be0bd0a428db8a78625a28bbf63","type":"text","conversion_output":true,"text":"management activities. Shibboleth is a standards-based, open source software package for web single","text_display":" management activities. Shibboleth is a standards-based, open source software package for web single","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1876,2582],[1876,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":373,"height":37},"line":47,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"8956071a43c84375ad0fad4c4e83543f","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 71","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-72","page":72,"lines":[{"cnt":[[245,251],[1811,251],[1811,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1568,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"696d4b9765b94c5ea07aad1796d8e08d","type":"text","conversion_output":true,"text":"sign-on across or within organizational boundaries. An overview of the DCC responsibilities and data","text_display":"\nsign-on across or within organizational boundaries. An overview of the DCC responsibilities and data","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[866,296],[866,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":622,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5113335f17044102a96ec1e71a1bf408","type":"text","conversion_output":true,"text":"management system is presented below.","text_display":" management system is presented below.","confidence":1,"confidence_rate":1},{"cnt":[[249,380],[1837,380],[1837,1510],[249,1510]],"region":{"top_left_x":249,"top_left_y":380,"width":1588,"height":1131},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"18835c6257324176bb1ac0479972ad35","type":"diagram","conversion_output":true,"text":"","text_display":"\n![](https://cdn.mathpix.com/cropped/8600e00f-80c7-48b1-9173-701d71d8c737-72.jpg?height=1131&width=1588&top_left_y=380&top_left_x=249)"},{"cnt":[[245,1558],[1852,1558],[1852,1605],[245,1605]],"region":{"top_left_x":244,"top_left_y":1557,"width":1608,"height":48},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a1958e239ad74424b6eac41436fb3191","type":"text","conversion_output":true,"text":"Study Integration: The UWA DCC team has extensive experience developing Application Programming","text_display":"\n\nStudy Integration: The UWA DCC team has extensive experience developing Application Programming","confidence":1,"confidence_rate":1},{"cnt":[[245,1603],[1850,1603],[1850,1646],[245,1646]],"region":{"top_left_x":244,"top_left_y":1602,"width":1606,"height":44},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cc5062e8fbc348cc8698d96f94527c35","type":"text","conversion_output":true,"text":"Interfaces (APIs), which allow multiple software programs to seamlessly interact and communicate with","text_display":" Interfaces (APIs), which allow multiple software programs to seamlessly interact and communicate with","confidence":1,"confidence_rate":1},{"cnt":[[245,1646],[1846,1646],[1846,1691],[245,1691]],"region":{"top_left_x":244,"top_left_y":1645,"width":1602,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"101385f2d7d641adab6fba1543f50df0","type":"text","conversion_output":true,"text":"one another in a simple and intuitive interface. The web portal API will serve as the wrapper for all data","text_display":" one another in a simple and intuitive interface. The web portal API will serve as the wrapper for all data","confidence":0.994140625,"confidence_rate":0.9999470589826054},{"cnt":[[245,1689],[1824,1689],[1824,1734],[245,1734]],"region":{"top_left_x":244,"top_left_y":1688,"width":1581,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ed5bc09390514449b20864bb1d7fb032","type":"text","conversion_output":true,"text":"management tools and software utilized in the LBP project, including: study ID assignment, screening,","text_display":" management tools and software utilized in the LBP project, including: study ID assignment, screening,","confidence":1,"confidence_rate":1},{"cnt":[[245,1732],[1876,1732],[1876,1777],[245,1777]],"region":{"top_left_x":244,"top_left_y":1731,"width":1632,"height":46},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"827b5ed4dc854dba9f2ec7408872f623","type":"text","conversion_output":true,"text":"centralized image storage (if needed), prospective data collection forms and surveys, and study operations","text_display":" centralized image storage (if needed), prospective data collection forms and surveys, and study operations","confidence":1,"confidence_rate":1},{"cnt":[[245,1777],[1755,1777],[1755,1822],[245,1822]],"region":{"top_left_x":244,"top_left_y":1776,"width":1512,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f663eabc2f4646b9a80d4999fe80fc96","type":"text","conversion_output":true,"text":"reporting. 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For each REDCap database,","text_display":" information, separating patient contact information from research study data. For each REDCap database,","confidence":1,"confidence_rate":1},{"cnt":[[245,1951],[1381,1951],[1381,1998],[245,1998]],"region":{"top_left_x":244,"top_left_y":1950,"width":1138,"height":49},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c004e8972a7d43ecbed671e84805f292","type":"text","conversion_output":true,"text":"the DCC will use distinct data access groups for clinical recruitment sites.","text_display":" the DCC will use distinct data access groups for clinical recruitment sites.","confidence":1,"confidence_rate":1},{"cnt":[[245,2041],[1807,2041],[1807,2086],[245,2086]],"region":{"top_left_x":244,"top_left_y":2041,"width":1563,"height":46},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"76ef0bba59d44198a035e81913ce6f6f","type":"text","conversion_output":true,"text":"Electronic Data Capture: The UWA DCC supports its own installation of REDCap, which is software","text_display":"\n\nElectronic Data Capture: The UWA DCC supports its own installation of REDCap, which is software","confidence":1,"confidence_rate":1},{"cnt":[[245,2084],[1777,2084],[1777,2129],[245,2129]],"region":{"top_left_x":244,"top_left_y":2083,"width":1533,"height":47},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9c32b3065ec14bea9600bd6b9823b6da","type":"text","conversion_output":true,"text":"specifically designed for electronic data capture that we have used successfully in several multi-site","text_display":" specifically designed for electronic data capture that we have used successfully in several multi-site","confidence":1,"confidence_rate":1},{"cnt":[[245,2127],[1764,2127],[1764,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2126,"width":1520,"height":47},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e9675765b9094bb08a0984e48fb91921","type":"text","conversion_output":true,"text":"clinical trials. REDCap features include differentiated user roles and privileges, password and user","text_display":" clinical trials. 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The web-based data management portal allows for four participant contact methods: research","text_display":" subject ID. The web-based data management portal allows for four participant contact methods: research","confidence":1,"confidence_rate":1},{"cnt":[[245,2346],[1800,2346],[1800,2391],[245,2391]],"region":{"top_left_x":244,"top_left_y":2346,"width":1557,"height":46},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c9b0b4788fd94742bbbc6aeb87ee427f","type":"text","conversion_output":true,"text":"coordinator data entry; electronic survey; computer-assisted telephone interviewing (CATI); or Short","text_display":" coordinator data entry; electronic survey; computer-assisted telephone interviewing (CATI); or Short","confidence":1,"confidence_rate":1},{"cnt":[[245,2391],[1846,2391],[1846,2436],[245,2436]],"region":{"top_left_x":244,"top_left_y":2391,"width":1602,"height":46},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3b28d3aa0f1b4d228b3713323595f582","type":"text","conversion_output":true,"text":"Message Service (SMS) text message. All survey modalities are customized to incorporate project logos","text_display":" Message Service (SMS) text message. All survey modalities are customized to incorporate project logos","confidence":0.9990234375,"confidence_rate":0.9999907826873115},{"cnt":[[245,2436],[1772,2436],[1772,2481],[245,2481]],"region":{"top_left_x":244,"top_left_y":2436,"width":1529,"height":46},"line":23,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"7b6f0736204c4412a48d49ec38761f6f","type":"text","conversion_output":true,"text":"and information to increase participant recognition and response rate. Furthermore, surveys may be","text_display":" and information to increase participant recognition and response rate. 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Dies, or they","text_display":"\n1. Dies, or they","confidence":1,"confidence_rate":1},{"cnt":[[305,713],[1046,713],[1046,758],[305,758]],"region":{"top_left_x":305,"top_left_y":713,"width":742,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0e29adf98f3848bc8b619b15c4be1abf","type":"text","conversion_output":true,"text":"2. Missed 3 consecutive monthly surveys, and","text_display":"\n2. Missed 3 consecutive monthly surveys, and","confidence":1,"confidence_rate":1},{"cnt":[[305,756],[1412,756],[1412,801],[305,801]],"region":{"top_left_x":305,"top_left_y":756,"width":1107,"height":46},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bf167f90ae704f34acce7b2c5099dce6","type":"text","conversion_output":true,"text":"3. Missed 4 consecutive weekly surveys ( \\(\\sim 1\\) consecutive month), and","text_display":"\n3. Missed 4 consecutive weekly surveys ( \\(\\sim 1\\) consecutive month), and","confidence":0.9970703125,"confidence_rate":0.9999623854839207},{"cnt":[[305,799],[1876,799],[1876,846],[305,846]],"region":{"top_left_x":305,"top_left_y":799,"width":1571,"height":48},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"475f733608c6474897d196c3eb0f11e8","type":"text","conversion_output":true,"text":"4. 3 email/text auto or manual reminders and 3 phone calls result in no response from the participant","text_display":"\n4. 3 email/text auto or manual reminders and 3 phone calls result in no response from the participant","confidence":1,"confidence_rate":1},{"cnt":[[245,889],[1729,889],[1729,935],[245,935]],"region":{"top_left_x":244,"top_left_y":889,"width":1486,"height":46},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"63ac374ed2fb42fc9fd36455d242a1e1","type":"text","conversion_output":true,"text":"When criteria 2-4 are met, the DCC will stop (turn off) the weekly and monthly surveys with the","text_display":"\n\nWhen criteria 2-4 are met, the DCC will stop (turn off) the weekly and monthly surveys with the","confidence":0.994140625,"confidence_rate":0.9999412356418027},{"cnt":[[245,932],[1858,932],[1858,982],[245,982]],"region":{"top_left_x":244,"top_left_y":932,"width":1615,"height":50},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"cf6de1d0e8b64370b9d71f3efae6a19e","type":"text","conversion_output":true,"text":"exception of the 6 and 12 month surveys (primary outcome). 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Free text data collection from study","text_display":" basis and reviewed weekly by the DCC protocol operations specialist. Free text data collection from study","confidence":1,"confidence_rate":1},{"cnt":[[245,1684],[1876,1684],[1876,1729],[245,1729]],"region":{"top_left_x":244,"top_left_y":1684,"width":1632,"height":46},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"59b36703a0244af08ad6050fdf7c853c","type":"text","conversion_output":true,"text":"participants will be minimized to the extent possible and field masking and automated out of range checks","text_display":" participants will be minimized to the extent possible and field masking and automated out of range checks","confidence":1,"confidence_rate":1},{"cnt":[[245,1727],[844,1727],[844,1772],[245,1772]],"region":{"top_left_x":244,"top_left_y":1727,"width":601,"height":46},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0a4957b9b7e04e32992a99fb2f55d248","type":"text","conversion_output":true,"text":"will be implemented where applicable.","text_display":" will be implemented where applicable.","confidence":1,"confidence_rate":1},{"cnt":[[245,1818],[1714,1818],[1714,1863],[245,1863]],"region":{"top_left_x":244,"top_left_y":1817,"width":1471,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f39b3538fc4341edbed2113db91bfbb6","type":"text","conversion_output":true,"text":"For ongoing data querying and cleaning, the DCC will implement and utilize a query resolution","text_display":"\n\nFor ongoing data querying and cleaning, the DCC will implement and utilize a query resolution","confidence":0.99951171875,"confidence_rate":0.9999950163338663},{"cnt":[[245,1861],[1818,1861],[1818,1906],[245,1906]],"region":{"top_left_x":244,"top_left_y":1860,"width":1574,"height":46},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4b2d004eb1cc4155849f0eaf356b921d","type":"text","conversion_output":true,"text":"dashboard where the protocol operations specialist will visually review \\(100 \\%\\) of all data entered in the","text_display":" dashboard where the protocol operations specialist will visually review \\(100 \\%\\) of all data entered in the","confidence":0.9829258918762207,"confidence_rate":0.9998448629230511},{"cnt":[[245,1904],[1811,1904],[1811,1949],[245,1949]],"region":{"top_left_x":244,"top_left_y":1903,"width":1568,"height":46},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"6b544a7291bd4195b216830fa88d20ba","type":"text","conversion_output":true,"text":"previous week and provide documentation that each participant-CRF has been reviewed. 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The protocol operations specialist will flag any data that trigger","text_display":" made broadly available to the study team. The protocol operations specialist will flag any data that trigger","confidence":0.9990234375,"confidence_rate":0.9999913536688149},{"cnt":[[245,2037],[1807,2037],[1807,2082],[245,2082]],"region":{"top_left_x":244,"top_left_y":2036,"width":1563,"height":46},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a20ed731238b4f60b3f9f2d2ec77b86b","type":"text","conversion_output":true,"text":"a review through logic-based checks, visual checks, or intermittent missing data. Research staff at the","text_display":" a review through logic-based checks, visual checks, or intermittent missing data. Research staff at the","confidence":1,"confidence_rate":1},{"cnt":[[245,2080],[1751,2080],[1751,2125],[245,2125]],"region":{"top_left_x":244,"top_left_y":2079,"width":1507,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d8533a6273e246a79288115b42ca5ebe","type":"text","conversion_output":true,"text":"recruitment sites will be asked to review each outstanding query and respond with \"confirmed\" or","text_display":" recruitment sites will be asked to review each outstanding query and respond with \"confirmed\" or","confidence":1,"confidence_rate":1},{"cnt":[[245,2123],[1824,2123],[1824,2172],[245,2172]],"region":{"top_left_x":244,"top_left_y":2122,"width":1581,"height":51},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"36b44d05d02e4a188c1b52e4371bb2b0","type":"text","conversion_output":true,"text":"\"corrected\" and may provide a comment beside each query to note relevant details. Each query will be","text_display":" \"corrected\" and may provide a comment beside each query to note relevant details. 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Data are managed by study number and","text_display":" participant identification number to maintain confidentiality. Data are managed by study number and","confidence":1,"confidence_rate":1},{"cnt":[[245,2415],[1841,2415],[1841,2462],[245,2462]],"region":{"top_left_x":244,"top_left_y":2414,"width":1598,"height":49},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c2526d623c2b4aa785889679d6a1e62e","type":"text","conversion_output":true,"text":"analyzed anonymously. All published reports will be of summary nature and no individual subjects will","text_display":" analyzed anonymously. All published reports will be of summary nature and no individual subjects will","confidence":1,"confidence_rate":1},{"cnt":[[1504,2582],[1871,2582],[1871,2619],[1504,2619]],"region":{"top_left_x":1503,"top_left_y":2582,"width":369,"height":37},"line":43,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"b5b2aa37d51d4181a55cfc2704bc2f9c","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 75","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-76","page":76,"lines":[{"cnt":[[245,251],[1828,251],[1828,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1585,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8e040a34db2a461bad9605877d624102","type":"text","conversion_output":true,"text":"be identified beyond the investigative staff involved. Responses to online surveys are encrypted during","text_display":"\nbe identified beyond the investigative staff involved. Responses to online surveys are encrypted during","confidence":1,"confidence_rate":1},{"cnt":[[245,296],[1820,296],[1820,342],[245,342]],"region":{"top_left_x":244,"top_left_y":296,"width":1576,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a137962ac8dd425dacbd2b44c08d6c69","type":"text","conversion_output":true,"text":"transmission to the study center and there is no outbound transmission of identifying information from","text_display":" transmission to the study center and there is no outbound transmission of identifying information from","confidence":1,"confidence_rate":1},{"cnt":[[245,339],[784,339],[784,387],[245,387]],"region":{"top_left_x":244,"top_left_y":339,"width":541,"height":48},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"354c261447b7465c8234ecc24a2a8299","type":"text","conversion_output":true,"text":"study servers to study participants.","text_display":" study servers to study participants.","confidence":1,"confidence_rate":1},{"cnt":[[245,425],[1809,425],[1809,475],[245,475]],"region":{"top_left_x":244,"top_left_y":425,"width":1565,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1b78f915a5b74ff3ad1ad41292668deb","type":"text","conversion_output":true,"text":"Information will not be released without written permission of the participant, except as necessary for","text_display":"\n\nInformation will not be released without written permission of the participant, except as necessary for","confidence":1,"confidence_rate":1},{"cnt":[[245,473],[1577,473],[1577,518],[245,518]],"region":{"top_left_x":244,"top_left_y":472,"width":1333,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"59d2e5d8b98a49669b5e1237d8ad7422","type":"text","conversion_output":true,"text":"monitoring by the IRB, the NCCIH, the OHRP, or other regulatory oversight agencies.","text_display":" monitoring by the IRB, the NCCIH, the OHRP, or other regulatory oversight agencies.","confidence":1,"confidence_rate":1},{"cnt":[[245,559],[1869,559],[1869,604],[245,604]],"region":{"top_left_x":244,"top_left_y":558,"width":1626,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"4ba71c8826274ef995cc89b046a5642d","type":"text","conversion_output":true,"text":"To further protect participant privacy, we have obtained a Certificate of Confidentiality from the National","text_display":"\n\nTo further protect participant privacy, we have obtained a Certificate of Confidentiality from the National","confidence":1,"confidence_rate":1},{"cnt":[[245,604],[1850,604],[1850,649],[245,649]],"region":{"top_left_x":244,"top_left_y":603,"width":1606,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b4e488c989d54b418a8afc5353592ed4","type":"text","conversion_output":true,"text":"Institutes of Health. The researchers can use this Certificate to legally refuse to disclose information that","text_display":" Institutes of Health. The researchers can use this Certificate to legally refuse to disclose information that","confidence":1,"confidence_rate":1},{"cnt":[[245,647],[1858,647],[1858,694],[245,694]],"region":{"top_left_x":244,"top_left_y":646,"width":1615,"height":48},"line":8,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"390c5906c26e457b9bbf53409364d5b0","type":"text","conversion_output":true,"text":"may identify participants in any federal, state, or local civil, criminal, administrative, legislative, or other","text_display":" may identify participants in any federal, state, or local civil, criminal, administrative, legislative, or other","confidence":1,"confidence_rate":1},{"cnt":[[245,692],[1820,692],[1820,737],[245,737]],"region":{"top_left_x":244,"top_left_y":691,"width":1576,"height":46},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8bc58fe1a5e94ae1bfe8e65d1298be55","type":"text","conversion_output":true,"text":"proceedings, for example, if there is a court subpoena. The researchers will use the Certificate to resist","text_display":" proceedings, for example, if there is a court subpoena. The researchers will use the Certificate to resist","confidence":1,"confidence_rate":1},{"cnt":[[245,735],[1618,735],[1618,782],[245,782]],"region":{"top_left_x":244,"top_left_y":734,"width":1374,"height":49},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"5ff250e404d94199b8abc9f7c57d5fd4","type":"text","conversion_output":true,"text":"any demands for information that would identify participants, except as explained below.","text_display":" any demands for information that would identify participants, except as explained below.","confidence":1,"confidence_rate":1},{"cnt":[[245,821],[1807,821],[1807,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1563,"height":51},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"21f00c4bfbd44cae94cdba51d5eea257","type":"text","conversion_output":true,"text":"The Certificate cannot be used to resist a demand for information from personnel of the United States","text_display":"\n\nThe Certificate cannot be used to resist a demand for information from personnel of the United States","confidence":0.99951171875,"confidence_rate":0.9999953924587458},{"cnt":[[245,868],[1467,868],[1467,913],[245,913]],"region":{"top_left_x":244,"top_left_y":867,"width":1224,"height":47},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ed6dd1872af24b09a1c4263a491232bb","type":"text","conversion_output":true,"text":"Government that is used for auditing or evaluation of federally funded projects.","text_display":" Government that is used for auditing or evaluation of federally funded projects.","confidence":1,"confidence_rate":1},{"cnt":[[245,954],[1878,954],[1878,1001],[245,1001]],"region":{"top_left_x":244,"top_left_y":953,"width":1634,"height":49},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e1bda618fdb940a798688ca7709caabd","type":"text","conversion_output":true,"text":"A Certificate of Confidentiality does not prevent participants from voluntarily releasing information about","text_display":"\n\nA Certificate of Confidentiality does not prevent participants from voluntarily releasing information about","confidence":1,"confidence_rate":1},{"cnt":[[245,1001],[1852,998],[1852,1044],[245,1046]],"region":{"top_left_x":244,"top_left_y":998,"width":1609,"height":49},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"45fca56eae284698a4c65b79d1547868","type":"text","conversion_output":true,"text":"themselves or their involvement in this research. If an insurer, employer, or other person obtains written","text_display":" themselves or their involvement in this research. If an insurer, employer, or other person obtains written","confidence":1,"confidence_rate":1},{"cnt":[[245,1044],[1854,1044],[1854,1089],[245,1089]],"region":{"top_left_x":244,"top_left_y":1044,"width":1611,"height":46},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"831f4f4636844259bf2951fa656c920f","type":"text","conversion_output":true,"text":"consent to receive research information, then the researchers may not use the Certificate to withhold that","text_display":" consent to receive research information, then the researchers may not use the Certificate to withhold that","confidence":1,"confidence_rate":1},{"cnt":[[245,1087],[443,1087],[443,1128],[245,1128]],"region":{"top_left_x":244,"top_left_y":1087,"width":199,"height":41},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2d74600f368b47bc977f9f1c4340aec5","type":"text","conversion_output":true,"text":"information.","text_display":" information.","confidence":1,"confidence_rate":1},{"cnt":[[245,1173],[1843,1173],[1843,1222],[245,1222]],"region":{"top_left_x":244,"top_left_y":1173,"width":1600,"height":50},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"530b2316ecad4d0e97ed5d73677c04b7","type":"text","conversion_output":true,"text":"If the investigators learn that a participant or someone with whom they are involved is in serious danger","text_display":"\n\nIf the investigators learn that a participant or someone with whom they are involved is in serious danger","confidence":1,"confidence_rate":1},{"cnt":[[245,1216],[1676,1216],[1676,1265],[245,1265]],"region":{"top_left_x":244,"top_left_y":1216,"width":1432,"height":50},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"514b2d303d47413e97d3165e38f51620","type":"text","conversion_output":true,"text":"or potential harm, they will need to inform, if required by state law, the appropriate agencies.","text_display":" or potential harm, they will need to inform, if required by state law, the appropriate agencies.","confidence":1,"confidence_rate":1},{"cnt":[[303,1343],[844,1343],[844,1403],[303,1403]],"region":{"top_left_x":302,"top_left_y":1342,"width":543,"height":61},"line":19,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"d0a76d2cb0134ce4a7d95dca35c841e7","type":"section_header","conversion_output":false,"children_ids":["fea86dee6ddc4d859bbc66a31bb14f7e"],"text":"","text_display":""},{"cnt":[[309,1349],[838,1349],[838,1399],[309,1399]],"region":{"top_left_x":309,"top_left_y":1349,"width":529,"height":50},"line":20,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"fea86dee6ddc4d859bbc66a31bb14f7e","type":"text","conversion_output":true,"parent_id":"d0a76d2cb0134ce4a7d95dca35c841e7","text":"11.4 Study Discontinuation","text_display":"\n\n\\subsection*{11.4 Study Discontinuation}","confidence":0.99951171875,"confidence_rate":0.9999842452693294},{"cnt":[[245,1418],[1792,1418],[1792,1463],[245,1463]],"region":{"top_left_x":244,"top_left_y":1417,"width":1548,"height":47},"line":21,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c4836f864a9e4646a76600043eb04948","type":"text","conversion_output":true,"text":"The study may be discontinued at any time by the IRB, the NCCIH, the OHRP, or other government","text_display":"\n\nThe study may be discontinued at any time by the IRB, the NCCIH, the OHRP, or other government","confidence":1,"confidence_rate":1},{"cnt":[[245,1461],[1474,1461],[1474,1506],[245,1506]],"region":{"top_left_x":244,"top_left_y":1460,"width":1230,"height":47},"line":22,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"97313d54fb9e411085f516b102af0121","type":"text","conversion_output":true,"text":"agencies as part of their duties to ensure that research participants are protected.","text_display":" agencies as part of their duties to ensure that research participants are protected.","confidence":1,"confidence_rate":1},{"cnt":[[243,1564],[612,1564],[612,1613],[243,1613]],"region":{"top_left_x":242,"top_left_y":1564,"width":371,"height":50},"line":23,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"b52ffeaa5e364b44871b73b20837a460","type":"section_header","conversion_output":false,"children_ids":["ac27193cddf1417ea6dbffdcdeee7a58"],"text":"","text_display":""},{"cnt":[[249,1568],[608,1568],[608,1609],[249,1609]],"region":{"top_left_x":249,"top_left_y":1568,"width":360,"height":42},"line":24,"column":0,"font_size":35,"is_printed":true,"is_handwritten":false,"id":"ac27193cddf1417ea6dbffdcdeee7a58","type":"text","conversion_output":true,"parent_id":"b52ffeaa5e364b44871b73b20837a460","text":"12. COMMITTEES","text_display":"\n\n\\section*{12. COMMITTEES}","confidence":1,"confidence_rate":1},{"cnt":[[241,1633],[827,1633],[827,1687],[241,1687]],"region":{"top_left_x":240,"top_left_y":1632,"width":588,"height":55},"line":25,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8aa9c6b713e34c929dca6441f0e67c20","type":"section_header","conversion_output":false,"children_ids":["b21fa182b80e4143906a9ecbdd7cf26e"],"text":"","text_display":""},{"cnt":[[245,1637],[823,1637],[823,1682],[245,1682]],"region":{"top_left_x":244,"top_left_y":1637,"width":579,"height":46},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b21fa182b80e4143906a9ecbdd7cf26e","type":"text","conversion_output":true,"parent_id":"8aa9c6b713e34c929dca6441f0e67c20","text":"Data Safety and Monitoring Board","text_display":"\n\n\\section*{Data Safety and Monitoring Board}","confidence":1,"confidence_rate":1},{"cnt":[[245,1680],[1772,1680],[1772,1725],[245,1725]],"region":{"top_left_x":244,"top_left_y":1680,"width":1529,"height":46},"line":27,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e7500a0e8993405a9e38384961737f34","type":"text","conversion_output":true,"text":"Appointed by NCCIH, the DSMB plays a crucial role in ensuring the safety and welfare of patients","text_display":"\n\nAppointed by NCCIH, the DSMB plays a crucial role in ensuring the safety and welfare of patients","confidence":1,"confidence_rate":1},{"cnt":[[245,1723],[1706,1723],[1706,1768],[245,1768]],"region":{"top_left_x":244,"top_left_y":1723,"width":1462,"height":46},"line":28,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a4643874a5ff416caad337fef36fddce","type":"text","conversion_output":true,"text":"enrolled in this trial, and operates without undue influence from any interested party, including","text_display":" enrolled in this trial, and operates without undue influence from any interested party, including","confidence":1,"confidence_rate":1},{"cnt":[[245,1766],[1880,1766],[1880,1815],[245,1815]],"region":{"top_left_x":244,"top_left_y":1766,"width":1636,"height":50},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e4acc4cdefe6465294ac7ecbd78b20f9","type":"text","conversion_output":true,"text":"PACBACK study investigators or NCCIH staff. DSMB responsibilities include protocol approval, interim","text_display":" PACBACK study investigators or NCCIH staff. DSMB responsibilities include protocol approval, interim","confidence":1,"confidence_rate":1},{"cnt":[[245,1813],[1790,1813],[1790,1858],[245,1858]],"region":{"top_left_x":244,"top_left_y":1813,"width":1546,"height":46},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b40fc30dc0f34773a0f88e156330287e","type":"text","conversion_output":true,"text":"review of trial enrollment, protocol compliance, and safety data. The protocol review committee is a","text_display":" review of trial enrollment, protocol compliance, and safety data. The protocol review committee is a","confidence":0.99658203125,"confidence_rate":0.9999673926902055},{"cnt":[[245,1856],[574,1856],[574,1897],[245,1897]],"region":{"top_left_x":244,"top_left_y":1856,"width":330,"height":42},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8520ffea2ea24be6a4b23de565d5cc2e","type":"text","conversion_output":true,"text":"subset of the DSMB.","text_display":" subset of the DSMB.","confidence":0.9658203125,"confidence_rate":0.9985519879668613},{"cnt":[[241,1938],[784,1938],[784,1992],[241,1992]],"region":{"top_left_x":240,"top_left_y":1937,"width":545,"height":55},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3ade6f36971741b5b8fb2a5eb1ba7c7f","type":"section_header","conversion_output":false,"children_ids":["b9ac6d1db1094064a981a3ee8c6e2343"],"text":"","text_display":""},{"cnt":[[245,1942],[778,1942],[778,1987],[245,1987]],"region":{"top_left_x":244,"top_left_y":1942,"width":534,"height":46},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"b9ac6d1db1094064a981a3ee8c6e2343","type":"text","conversion_output":true,"parent_id":"3ade6f36971741b5b8fb2a5eb1ba7c7f","text":"PACBACK Steering Committee","text_display":"\n\n\\section*{PACBACK Steering Committee}","confidence":1,"confidence_rate":1},{"cnt":[[245,1987],[1848,1987],[1848,2035],[245,2035]],"region":{"top_left_x":244,"top_left_y":1987,"width":1604,"height":48},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"83340577bcc04fb8b5629e0fa799151a","type":"text","conversion_output":true,"text":"The Steering Committee will assume responsibility for the overall direction of this study which includes","text_display":"\n\nThe Steering Committee will assume responsibility for the overall direction of this study which includes","confidence":1,"confidence_rate":1},{"cnt":[[245,2032],[1846,2032],[1846,2078],[245,2078]],"region":{"top_left_x":244,"top_left_y":2032,"width":1602,"height":46},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"3aedefe6d598464d89cfbe9d52daab8b","type":"text","conversion_output":true,"text":"design and conduct of the study; preparation of essential study documents (e.g., study protocol, protocol","text_display":" design and conduct of the study; preparation of essential study documents (e.g., study protocol, protocol","confidence":0.99951171875,"confidence_rate":0.9999955600053285},{"cnt":[[245,2075],[1783,2075],[1783,2121],[245,2121]],"region":{"top_left_x":244,"top_left_y":2075,"width":1540,"height":46},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"23e2c5f416e542979aba6402f6819270","type":"text","conversion_output":true,"text":"amendments, and data collection forms); monitoring recruitment and retention of study participants;","text_display":" amendments, and data collection forms); monitoring recruitment and retention of study participants;","confidence":1,"confidence_rate":1},{"cnt":[[245,2118],[1869,2118],[1869,2168],[245,2168]],"region":{"top_left_x":244,"top_left_y":2118,"width":1626,"height":50},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9f14eb373f8f45f99a9e82f28db9a6b1","type":"text","conversion_output":true,"text":"changes in study procedures as appropriate; review of study progress in achieving study goals/milestones;","text_display":" changes in study procedures as appropriate; review of study progress in achieving study goals/milestones;","confidence":1,"confidence_rate":1},{"cnt":[[245,2161],[1824,2161],[1824,2211],[245,2211]],"region":{"top_left_x":244,"top_left_y":2161,"width":1581,"height":50},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"2b03868bc3b2422e85e079efc9dc2d31","type":"text","conversion_output":true,"text":"review and implementation of recommendations from the DSMB; review and respond to other general","text_display":" review and implementation of recommendations from the DSMB; review and respond to other general","confidence":1,"confidence_rate":1},{"cnt":[[245,2209],[1858,2209],[1858,2254],[245,2254]],"region":{"top_left_x":244,"top_left_y":2208,"width":1615,"height":46},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9379b64cf02e4d36908cd19d30fa8fe9","type":"text","conversion_output":true,"text":"advice and/or recommendations (e.g., from the NCCIH program officer and the PIs). The committee will","text_display":" advice and/or recommendations (e.g., from the NCCIH program officer and the PIs). The committee will","confidence":1,"confidence_rate":1},{"cnt":[[245,2252],[1852,2252],[1852,2297],[245,2297]],"region":{"top_left_x":244,"top_left_y":2251,"width":1608,"height":46},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"81db89cbd8c849bc864897df215a3d27","type":"text","conversion_output":true,"text":"make recommendations via email correspondence. If requested by a majority of members, or by NCCIH","text_display":" make recommendations via email correspondence. 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National Center for Complementary and Integrative Health. 2016 Strategic Plan, 2016.","confidence":1,"confidence_rate":1},{"cnt":[[1502,2582],[1880,2582],[1880,2619],[1502,2619]],"region":{"top_left_x":1501,"top_left_y":2582,"width":379,"height":37},"line":52,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"d56ac21681dc4254a8afaa8ca0b764b3","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 79","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-80","page":80,"lines":[{"cnt":[[245,251],[1803,251],[1803,299],[245,299]],"region":{"top_left_x":244,"top_left_y":251,"width":1559,"height":48},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"207cc57d45f04b4c9f20b4d648092eae","type":"text","conversion_output":true,"text":"32. Hoy D, Bain C, Williams G, et al. 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Frymoyer JW. Back pain and sciatica. N Engl J Med 1988;318(5):291-300. doi:","text_display":"\n33. Frymoyer JW. Back pain and sciatica. N Engl J Med 1988;318(5):291-300. doi:","confidence":0.98974609375,"confidence_rate":0.999877307054688},{"cnt":[[372,425],[1450,425],[1450,475],[372,475]],"region":{"top_left_x":371,"top_left_y":425,"width":1080,"height":50},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"fe840193755a4a25ac557b839c6d4690","type":"text","conversion_output":true,"text":"10.1056/nejm198802043180506 [published Online First: 1988/02/04]","text_display":" 10.1056/nejm198802043180506 [published Online First: 1988/02/04]","confidence":0.9951221942901611,"confidence_rate":0.9999291366988636},{"cnt":[[245,471],[1661,471],[1661,518],[245,518]],"region":{"top_left_x":244,"top_left_y":470,"width":1417,"height":48},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"93338a76c56b46ffb5b0da7c4f217c7b","type":"text","conversion_output":true,"text":"34. Chou R, Shekelle P. Will this patient develop persistent disabling low back pain? 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Lost productive time and cost due to common pain conditions in","confidence":1,"confidence_rate":1},{"cnt":[[370,735],[1620,735],[1620,780],[370,780]],"region":{"top_left_x":369,"top_left_y":734,"width":1251,"height":46},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"196d03cfcec04a528d0c8f4708560c79","type":"text","conversion_output":true,"text":"the US workforce. JAMA 2003;290(18):2443-54. doi: 10.1001/jama.290.18.2443","text_display":" the US workforce. JAMA 2003;290(18):2443-54. doi: 10.1001/jama.290.18.2443","confidence":0.9990234375,"confidence_rate":0.9999876324859995},{"cnt":[[245,778],[1781,778],[1781,827],[245,827]],"region":{"top_left_x":244,"top_left_y":777,"width":1538,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"557992f6b64a4379b8e9bebea54c7c27","type":"text","conversion_output":true,"text":"37. Carey TS, Freburger JK, Holmes GM, et al. 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Framework of policy recommendations for implementation of","text_display":"\n47. Ubbink DT, Guyatt GH, Vermeulen H. Framework of policy recommendations for implementation of","confidence":1,"confidence_rate":1},{"cnt":[[370,2054],[1609,2054],[1609,2099],[370,2099]],"region":{"top_left_x":369,"top_left_y":2053,"width":1241,"height":47},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"96c9d2f102794b21bad3a2929990354b","type":"text","conversion_output":true,"text":"evidence-based practice: a systematic scoping review. BMJ Open 2013;3(1) doi:","text_display":" evidence-based practice: a systematic scoping review. 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Racine DP. Reliable effectiveness: a theory on sustaining and replicating worthwhile innovations.","text_display":"\n52. Racine DP. Reliable effectiveness: a theory on sustaining and replicating worthwhile innovations.","confidence":1,"confidence_rate":1},{"cnt":[[365,602],[1867,602],[1867,651],[365,651]],"region":{"top_left_x":365,"top_left_y":601,"width":1502,"height":50},"line":9,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1fd54e119e4140e38524287bc549e6dd","type":"text","conversion_output":true,"text":"Adm Policy Ment Health 2006;33(3):356-87. doi: 10.1007/s10488-006-0047-1 [published Online","text_display":" Adm Policy Ment Health 2006;33(3):356-87. doi: 10.1007/s10488-006-0047-1 [published Online","confidence":0.99951171875,"confidence_rate":0.9999948589553403},{"cnt":[[370,645],[657,645],[657,694],[370,694]],"region":{"top_left_x":369,"top_left_y":644,"width":289,"height":50},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ae6f170cd59743489eaa755402e4dd67","type":"text","conversion_output":true,"text":"First: 2006/06/07]","text_display":" First: 2006/06/07]","confidence":1,"confidence_rate":1},{"cnt":[[245,690],[1800,690],[1800,737],[245,737]],"region":{"top_left_x":244,"top_left_y":689,"width":1557,"height":48},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"db2e6b2df08e4ab1abfb6d794c8bb504","type":"text","conversion_output":true,"text":"53. 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Fostering implementation of health services research","confidence":1,"confidence_rate":1},{"cnt":[[370,735],[1721,735],[1721,782],[370,782]],"region":{"top_left_x":369,"top_left_y":734,"width":1352,"height":49},"line":12,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"87b0bbae1bb343278af59a191a7de6f1","type":"text","conversion_output":true,"text":"findings into practice: a consolidated framework for advancing implementation science.","text_display":" findings into practice: a consolidated framework for advancing implementation science.","confidence":1,"confidence_rate":1},{"cnt":[[370,778],[1803,778],[1803,827],[370,827]],"region":{"top_left_x":369,"top_left_y":777,"width":1434,"height":51},"line":13,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"119ec3fc5ccc4b039071b5ce72ebcb3f","type":"text","conversion_output":true,"text":"Implement Sci 2009;4:50. doi: 10.1186/1748-5908-4-50 [published Online First: 2009/08/12]","text_display":" Implement Sci 2009;4:50. doi: 10.1186/1748-5908-4-50 [published Online First: 2009/08/12]","confidence":0.9970703125,"confidence_rate":0.9999687878548241},{"cnt":[[245,821],[1876,821],[1876,870],[245,870]],"region":{"top_left_x":244,"top_left_y":820,"width":1632,"height":51},"line":14,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"9f658cad459b401b9e22ae31f88a4553","type":"text","conversion_output":true,"text":"54. McGoey T, Root Z, Bruner MW, et al. Evaluation of physical activity interventions in children via the","text_display":"\n54. McGoey T, Root Z, Bruner MW, et al. Evaluation of physical activity interventions in children via the","confidence":1,"confidence_rate":1},{"cnt":[[370,866],[1863,866],[1863,913],[370,913]],"region":{"top_left_x":369,"top_left_y":865,"width":1494,"height":49},"line":15,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"abdc2995530e4a918600e36b5d0c300e","type":"text","conversion_output":true,"text":"reach, efficacy/effectiveness, adoption, implementation, and maintenance (RE-AIM) framework:","text_display":" reach, efficacy/effectiveness, adoption, implementation, and maintenance (RE-AIM) framework:","confidence":1,"confidence_rate":1},{"cnt":[[370,911],[1798,911],[1798,956],[370,956]],"region":{"top_left_x":369,"top_left_y":910,"width":1430,"height":47},"line":16,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ad984886b88a439ba5412ebc5326eafd","type":"text","conversion_output":true,"text":"A systematic review of randomized and non-randomized trials. Prev Med 2016;82:8-19. doi:","text_display":" A systematic review of randomized and non-randomized trials. Prev Med 2016;82:8-19. doi:","confidence":1,"confidence_rate":1},{"cnt":[[372,954],[1412,954],[1412,1003],[372,1003]],"region":{"top_left_x":371,"top_left_y":953,"width":1041,"height":51},"line":17,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c25bf85f77dc49eba88145f62addfedd","type":"text","conversion_output":true,"text":"10.1016/j.ypmed.2015.11.004 [published Online First: 2015/11/20]","text_display":" 10.1016/j.ypmed.2015.11.004 [published Online First: 2015/11/20]","confidence":1,"confidence_rate":1},{"cnt":[[245,999],[1820,999],[1820,1046],[245,1046]],"region":{"top_left_x":244,"top_left_y":999,"width":1576,"height":48},"line":18,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"243331367c334ea9af5009fe0c2edb4a","type":"text","conversion_output":true,"text":"55. Almeida FA, You W, Harden SM, et al. 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Jang M, Chao A, Whittemore R. 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Irvine AB, Russell H, Manocchia M, et al. Mobile-Web app to self-manage low back pain:","text_display":"\n57. Irvine AB, Russell H, Manocchia M, et al. Mobile-Web app to self-manage low back pain:","confidence":0.99951171875,"confidence_rate":0.9999948589553403},{"cnt":[[370,1349],[1876,1349],[1876,1399],[370,1399]],"region":{"top_left_x":369,"top_left_y":1349,"width":1507,"height":50},"line":26,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"710b29f7d7424e109d39251b9793e866","type":"text","conversion_output":true,"text":"randomized controlled trial. J Med Internet Res 2015;17(1):e1. doi: 10.2196/jmir. 3130 [published","text_display":" randomized controlled trial. 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Comparison of back pain prognostic risk","confidence":1,"confidence_rate":1},{"cnt":[[370,1482],[1751,1482],[1751,1532],[370,1532]],"region":{"top_left_x":369,"top_left_y":1482,"width":1382,"height":50},"line":29,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ee7cf26d3cbe4033b924acbd6efd2061","type":"text","conversion_output":true,"text":"stratification item sets. The journal of pain : official journal of the American Pain Society","text_display":" stratification item sets. The journal of pain : official journal of the American Pain Society","confidence":0.99755859375,"confidence_rate":0.9999750575422747},{"cnt":[[370,1525],[1149,1525],[1149,1575],[370,1575]],"region":{"top_left_x":369,"top_left_y":1525,"width":781,"height":50},"line":30,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"048f80d7d5864b7383b23e725aa4db27","type":"text","conversion_output":true,"text":"2014;15(1):81-9. doi: 10.1016/j.jpain.2013.09.013","text_display":" 2014;15(1):81-9. doi: 10.1016/j.jpain.2013.09.013","confidence":0.9970703125,"confidence_rate":0.9999456683753719},{"cnt":[[245,1571],[1837,1571],[1837,1618],[245,1618]],"region":{"top_left_x":244,"top_left_y":1570,"width":1593,"height":48},"line":31,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"96dbdd0189f1458493b72cd7ab4ae684","type":"text","conversion_output":true,"text":"59. Hill JC, Whitehurst DG, Lewis M, et al. Comparison of stratified primary care management for low","text_display":"\n59. Hill JC, Whitehurst DG, Lewis M, et al. Comparison of stratified primary care management for low","confidence":1,"confidence_rate":1},{"cnt":[[370,1613],[1732,1613],[1732,1661],[370,1661]],"region":{"top_left_x":369,"top_left_y":1613,"width":1363,"height":48},"line":32,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"27ec59dc623741679c51cb96406a400b","type":"text","conversion_output":true,"text":"back pain with current best practice (STarT Back): a randomised controlled trial. Lancet","text_display":" back pain with current best practice (STarT Back): a randomised controlled trial. Lancet","confidence":1,"confidence_rate":1},{"cnt":[[370,1659],[1734,1659],[1734,1704],[370,1704]],"region":{"top_left_x":369,"top_left_y":1658,"width":1365,"height":46},"line":33,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f80b2683e8654693beea1b79e377e718","type":"text","conversion_output":true,"text":"2011;378(9802):1560-71. doi: 10.1016/s0140-6736(11)60937-9 [published Online First:","text_display":" 2011;378(9802):1560-71. doi: 10.1016/s0140-6736(11)60937-9 [published Online First:","confidence":1,"confidence_rate":1},{"cnt":[[370,1702],[569,1702],[569,1747],[370,1747]],"region":{"top_left_x":369,"top_left_y":1701,"width":201,"height":46},"line":34,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"657f0479132f408381b7ef0bb2eb2223","type":"text","conversion_output":true,"text":"2011/10/04]","text_display":" 2011/10/04]","confidence":1,"confidence_rate":1},{"cnt":[[245,1745],[1858,1745],[1858,1794],[245,1794]],"region":{"top_left_x":244,"top_left_y":1744,"width":1615,"height":50},"line":35,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"79da0e31bfcb47538824143cc0174999","type":"text","conversion_output":true,"text":"60. Foster NE, Delitto A. Embedding psychosocial perspectives within clinical management of low back","text_display":"\n60. Foster NE, Delitto A. Embedding psychosocial perspectives within clinical management of low back","confidence":1,"confidence_rate":1},{"cnt":[[370,1788],[1772,1788],[1772,1837],[370,1837]],"region":{"top_left_x":369,"top_left_y":1787,"width":1404,"height":50},"line":36,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"458e3ee19e73440b963a624b7e8a3e78","type":"text","conversion_output":true,"text":"pain: integration of psychosocially informed management principles into physical therapist","text_display":" pain: integration of psychosocially informed management principles into physical therapist","confidence":1,"confidence_rate":1},{"cnt":[[370,1835],[1534,1835],[1534,1880],[370,1880]],"region":{"top_left_x":369,"top_left_y":1834,"width":1165,"height":46},"line":37,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"1faa1c45f79c444f910ebf63713ce348","type":"text","conversion_output":true,"text":"practice--challenges and opportunities. Phys Ther 2011;91(5):790-803. doi:","text_display":" practice--challenges and opportunities. Phys Ther 2011;91(5):790-803. doi:","confidence":1,"confidence_rate":1},{"cnt":[[374,1878],[1291,1878],[1291,1927],[374,1927]],"region":{"top_left_x":373,"top_left_y":1877,"width":919,"height":51},"line":38,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"a808a1900d2e4d718e3be801bdf74bf1","type":"text","conversion_output":true,"text":"10.2522/ptj. 20100326 [published Online First: 2011/04/01]","text_display":" 10.2522/ptj. 20100326 [published Online First: 2011/04/01]","confidence":0.7224822044372559,"confidence_rate":0.9950869196169648},{"cnt":[[245,1921],[1772,1921],[1772,1970],[245,1970]],"region":{"top_left_x":244,"top_left_y":1920,"width":1529,"height":51},"line":39,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"c019d2f154cf4f1d95eab4c7a69c6ec0","type":"text","conversion_output":true,"text":"61. Brunner E, De Herdt A, Minguet P, et al. Can cognitive behavioural therapy based strategies be","text_display":"\n61. Brunner E, De Herdt A, Minguet P, et al. Can cognitive behavioural therapy based strategies be","confidence":0.99951171875,"confidence_rate":0.9999952582588333},{"cnt":[[370,1966],[1846,1966],[1846,2013],[370,2013]],"region":{"top_left_x":369,"top_left_y":1965,"width":1477,"height":49},"line":40,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"eaf9e2323dde4c30bfefbd47fbc613cc","type":"text","conversion_output":true,"text":"integrated into physiotherapy for the prevention of chronic low back pain? A systematic review.","text_display":" integrated into physiotherapy for the prevention of chronic low back pain? A systematic review.","confidence":1,"confidence_rate":1},{"cnt":[[370,2007],[1841,2007],[1841,2056],[370,2056]],"region":{"top_left_x":369,"top_left_y":2006,"width":1473,"height":51},"line":41,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"bbc21ee449724070bb7d99d96e82fccf","type":"text","conversion_output":true,"text":"Disabil Rehabil 2013;35(1):1-10. doi: 10.3109/09638288.2012.683848 [published Online First:","text_display":" Disabil Rehabil 2013;35(1):1-10. doi: 10.3109/09638288.2012.683848 [published Online First:","confidence":0.9990234375,"confidence_rate":0.999989822555459},{"cnt":[[370,2054],[569,2054],[569,2099],[370,2099]],"region":{"top_left_x":369,"top_left_y":2053,"width":201,"height":47},"line":42,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"f117143cb21c4c188ed52d678eecb31c","type":"text","conversion_output":true,"text":"2012/05/23]","text_display":" 2012/05/23]","confidence":1,"confidence_rate":1},{"cnt":[[245,2097],[1665,2097],[1665,2146],[245,2146]],"region":{"top_left_x":244,"top_left_y":2096,"width":1422,"height":51},"line":43,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"49cb98357ae74a4c9293bc9b6b89fc3a","type":"text","conversion_output":true,"text":"62. 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Causal inference from longitudinal studies with baseline randomization. The","text_display":"\n162. Toh S, Hernan MA. Causal inference from longitudinal studies with baseline randomization. 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Sitlani CM, Heagerty PJ, Blood EA, et al. Longitudinal structural mixed models for the analysis of","text_display":"\n163. Sitlani CM, Heagerty PJ, Blood EA, et al. Longitudinal structural mixed models for the analysis of","confidence":1,"confidence_rate":1},{"cnt":[[367,2185],[1669,2185],[1669,2232],[367,2232]],"region":{"top_left_x":367,"top_left_y":2184,"width":1303,"height":49},"line":45,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"8832629ece76493a8b08cd0eb7ba2549","type":"text","conversion_output":true,"text":"surgical trials with noncompliance. Statistics in medicine 2012;31(16):1738-60. doi:","text_display":" surgical trials with noncompliance. 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Research Design: Qualitative, Quantitative, and Mixed Methods Approaches: SAGE","confidence":1,"confidence_rate":1},{"cnt":[[365,2402],[664,2402],[664,2451],[365,2451]],"region":{"top_left_x":365,"top_left_y":2401,"width":299,"height":51},"line":50,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"049b0588b1a944d2a22c3c6df67f545a","type":"text","conversion_output":true,"text":"Publications 2013.","text_display":" Publications 2013.","confidence":1,"confidence_rate":1},{"cnt":[[1500,2578],[1884,2578],[1884,2619],[1500,2619]],"region":{"top_left_x":1499,"top_left_y":2578,"width":386,"height":41},"line":51,"column":0,"font_size":22,"is_printed":true,"is_handwritten":false,"id":"7d41af1e8ff8429292f81b79a34d0b2b","type":"page_info","conversion_output":false,"text":"PACBACK Protocol V8 page 87","text_display":"","confidence":1,"confidence_rate":1}],"page_height":2750,"page_width":2125,"languages_detected":[]},{"image_id":"8600e00f-80c7-48b1-9173-701d71d8c737-88","page":88,"lines":[{"cnt":[[247,249],[1712,249],[1712,299],[247,299]],"region":{"top_left_x":247,"top_left_y":249,"width":1466,"height":50},"line":1,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"d9d50b1bc27f43f3a997b57555f0467b","type":"text","conversion_output":true,"text":"166. Pope C, Mays N. Qualitative Research: Reaching the parts other methods cannot reach: an","text_display":"\n166. Pope C, Mays N. Qualitative Research: Reaching the parts other methods cannot reach: an","confidence":1,"confidence_rate":1},{"cnt":[[370,296],[1579,296],[1579,342],[370,342]],"region":{"top_left_x":369,"top_left_y":296,"width":1211,"height":46},"line":2,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"347e58d4cbdf43c28986c9772990fc66","type":"text","conversion_output":true,"text":"introduction to qualitative methods in health and health services research. Bmj","text_display":" introduction to qualitative methods in health and health services research. Bmj","confidence":0.99951171875,"confidence_rate":0.9999941857252588},{"cnt":[[372,339],[1210,339],[1210,385],[372,385]],"region":{"top_left_x":371,"top_left_y":339,"width":839,"height":46},"line":3,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"043456d5598e425ba5c7af00f8640824","type":"text","conversion_output":true,"text":"1995;311(6996):42-45. doi: 10.1136/bmj.311.6996.42","text_display":" 1995;311(6996):42-45. doi: 10.1136/bmj.311.6996.42","confidence":1,"confidence_rate":1},{"cnt":[[247,382],[1704,382],[1704,432],[247,432]],"region":{"top_left_x":247,"top_left_y":382,"width":1457,"height":50},"line":4,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0b5e955aa7814f1ba3683fbb56bcf9c6","type":"text","conversion_output":true,"text":"167. Bauer M. Classical Content Analysis: A Review. In: Bauer M, Gaskell G., ed. Qualitative","text_display":"\n167. Bauer M. Classical Content Analysis: A Review. In: Bauer M, Gaskell G., ed. Qualitative","confidence":1,"confidence_rate":1},{"cnt":[[370,430],[1828,430],[1828,475],[370,475]],"region":{"top_left_x":369,"top_left_y":429,"width":1460,"height":46},"line":5,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"34250a8c01984d1db76e44ead672cbf9","type":"text","conversion_output":true,"text":"Researching with Text, Image and Sound: A Practical Handbook for Social Research. London,","text_display":" Researching with Text, Image and Sound: A Practical Handbook for Social Research. London,","confidence":0.99951171875,"confidence_rate":0.999994804263518},{"cnt":[[370,473],[1018,473],[1018,518],[370,518]],"region":{"top_left_x":369,"top_left_y":472,"width":650,"height":46},"line":6,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"0ff2f21cc01f4b24baaf8f7ffe79ffce","type":"text","conversion_output":true,"text":"UK: Sage Publications, Inc. 2000:131-51.","text_display":" UK: Sage Publications, Inc. 2000:131-51.","confidence":0.841796875,"confidence_rate":0.9961802796523744},{"cnt":[[247,516],[1704,516],[1704,561],[247,561]],"region":{"top_left_x":247,"top_left_y":515,"width":1457,"height":46},"line":7,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"da654aa1405c47e3b911a944da22338b","type":"text","conversion_output":true,"text":"168. Lincoln Y, Guba E. Naturalistic Inquiry. Beverly Hills, CA: Sage Publications, Inc. 1985.","text_display":"\n168. Lincoln Y, Guba E. Naturalistic Inquiry. 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Eur Spine J 2013;22(9):1986-","text_display":" expectations regarding treatment? Content analysis of interviews. Eur Spine J 2013;22(9):1986","confidence":0.99951171875,"confidence_rate":0.9999950666738041},{"cnt":[[370,649],[1515,649],[1515,694],[370,694]],"region":{"top_left_x":369,"top_left_y":648,"width":1146,"height":46},"line":10,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"ca84b3f8985b43eb8dd349628c4cd20e","type":"text","conversion_output":true,"text":"95. doi: 10.1007/s00586-013-2803-8 [published Online First: 2013/05/11]","text_display":"95. doi: 10.1007/s00586-013-2803-8 [published Online First: 2013/05/11]","confidence":0.9985356330871582,"confidence_rate":0.9999807180787152},{"cnt":[[247,690],[1820,690],[1820,737],[247,737]],"region":{"top_left_x":247,"top_left_y":689,"width":1573,"height":48},"line":11,"column":0,"font_size":28,"is_printed":true,"is_handwritten":false,"id":"e7d9f5bbb661473a9a11a7f39b513a14","type":"text","conversion_output":true,"text":"170. Little RJA, Rubin DB. Statistical analysis with missing data. 2nd ed. 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