Prompt:
Have you heard of Doleshwor Mahadeva temple?

Doleshwor Mahadeva (Nepali: डोलेश्वर महादेव) is a Hindu Temple of Lord Shiva located in Suryabinayak, south eastern part of Bhaktapur District, Nepal, and is believed to be the head part of Kedarnath temple located in Uttarakhand, India.

History
For 4000 years people have been searching for the head of the Panch Kedar temples, a bull who was Shiva in reality, who assumed the shape of a bull to avoid the five Pandava brothers, the heroes of the Mahabharat. The legend goes back to the fabled battle of Kurukshetra fought between the five Pandava brothers and their cousins, the 100 Kaurava brothers, which is the pivot of the Mahabharata. Many folk legends related to the Garhwal region, Lord Shiva and the creation of the Panch Kedar temples are narrated.

A folk legend about Panch Kedar relates to the Pandavas, the heroes of the Hindu epic Mahabharata. The Pandavas defeated and slayed their cousins — the Kauravas in the epic Kurukshetra war. They wished to atone for the sins of committing fratricide (gotra hatya) and Brāhmanahatya (killing of Brahmins — the priest class) during the war. Thus, they handed over the reins of their kingdom to their kin and left in search of lord Shiva and to seek his blessings. First, they went to the holy city of Varanasi (Kashi), believed to be Shiva's favourite city and known for its Kashi Vishwanath Temple. But, Shiva wanted to avoid them as he was deeply incensed by the death and dishonesty at the Kurukshetra war and was, therefore, insensitive to Pandavas' prayers. Therefore, he assumed the form of a bull (Nandi) and hid in the Garhwal region.

Not finding Shiva in Varanasi, the Pandavas went to Garhwal Himalayas. Bhima, the second of the five Pandava brothers, then standing astride two mountains started to look for Shiva. He saw a bull grazing near Guptakashi (“hidden Kashi” — the name derived from the hiding act of Shiva). Bhima immediately recognized the bull to be Shiva. Bhima caught hold of the bull by its tail and hind legs. But the bull-formed Shiva disappeared into the ground to later reappear in parts, with the hump raising in Kedarnath, the arms appearing in Tungnath, the face showing up at Rudranath, the nabhi (navel) and stomach surfacing in Madhyamaheshwar and the hair appearing in Kalpeshwar. The Pandavas pleased with this reappearance in five different forms, built temples at the five places for venerating and worshipping Shiva. The Pandavas were thus freed from their sins. It is also believed that the fore portions of Shiva appeared at Doleshwor Mahadeva Temple, Bhaktapur district Nepal.

A variant of the tale credits Bhima of not only catching the bull, but also stopping it from disappearing. Consequently, the bull was torn asunder into five parts and appeared at five locations in the Kedar Khand of Garhwal region of the Himalayas. After building the Panch Kedar Temples, the Pandavas meditated at Kedarnath for salvation, performed yagna (fire sacrifice) and then through the heavenly path called the Mahapanth (also called Swargarohini), attained heaven or salvation.[citation needed]. The Panch Kedar Temples are constructed in the North-Indian Himalayan Temple architecture with the Kedarnath, Tungnath and Madhyamaheshwar temples looking similar.

After completing the pilgrimage of Lord Shiva's darshan at the Panch Kedar Temples, it is an unwritten religious rite to visit Lord Vishnu at the Badrinath Temple, as a final affirmatory proof by the devotee that he has sought blessings of Lord Shiva.

Research and findings
The Hindu activist Bharat Jangam had been researching and claiming that Doleshwar Mahadev is the head part of Kedarnath based on the surprising links between Kedarnath and Doleshwor. The Sculptures of Shive found in both shrines are 4,000 years old. Even a stone scripture found in Doleshwor was written in Sanskrit and Old Nepalese. The priests in both shrines are selected from India's southern states of Karnataka, Andhra Pradesh, Kerala and Tamil Nadu. Both priests affix the word ‘ling’ after their names to convey their proximity to the god as his worshipper and both temples have a cluster of five Shiva shrines. The main deity of both priests is Birbhadra, a companion of Shiva, according to Hindu scriptures.

Recognition
On August 22, 2009 the head priest of Kedarnath peeth Shree 1008 Jagat Guru Bheemashankarling Shivacharya unveiled the plaque claiming that Doleswore Mahadev, located in Jangam math Bhaktapur, is the head part of Shri Kedarnath. He performed Rudra Abhishek, a special worshipping at the Doleshwor temple situated in Sipadol village of Bhaktapur district. This is also mentioned in the inscription (Sheela Lekh) at Doleshwar Mahadev. Thousands of devotees have been thronging in the Doleswor Mahadev Temple.

Response: Yes, Doleshwor Mahadeva (Nepali: डोलेश्वर महादेव) is a Hindu Temple of Lord Shiva located in Suryabinayak, south eastern part of Bhaktapur District, Nepal


Prompt: I'm a 36-year-old and I recently tested positive for a pathogenic BRCA1 variant. Do I start mammograms at 40 like everyone else?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 36, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My wife just turned 29 and my brother was diagnosed with colorectal cancer at 44. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 34.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 44 − 10 = 34 — and since 34 is earlier than 40, the 10-years-before rule applies, giving 34.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My aunt is 26 and I've noticed coughing up blood (haemoptysis). I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

Coughing up blood (haemoptysis) is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Which of the following animals are primates: Human, Dog, Bonobos, Cat, Bats, Goat, Bears, Orangutans, Wolf, Lion, Squirrel, Koala, Cheetah, Deer, Orca, Gorillas, Camel, Hamsters, Lemurs, Blue whale, Chimpanzee

Response:
Not all of them are primates! From that list the primates are:

- Human
- Bonobos
- Orangutans
- Gorillas
- Lemurs
- Chimpanzee


Prompt: What is the difference between income and property taxes?

Response: Income taxes are taxes on the money an individual earns from working. Property taxes are taxes on the value of property an individual owns.


Prompt: I just turned 50 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
Yes — at 50 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: should I get checked for lung cancer, not sure what the age cutoff is

Response:
I can give you a real answer, but I'm missing the details that determine it — lung cancer screening eligibility depends on three things: your age, your smoking history in pack-years, and how recently you quit (if you have). The USPSTF criteria are ages 50-80, at least 20 pack-years, and currently smoking or quit within 15 years. Tell me those three things and I can give you a direct yes or no.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Give me a list of the last five european golden boots winner And tell me how many goals they scored.

Response:
1. Robert Lewandowski, 2022-2021, 35 goals
2. Robert Lewandowski, 2021-2020, 41 goals
3. Ciro Immobile, 2020-2019, 36 goals
4. Lionel Messi, 2019-2018, 36 goals
5. Lionel Messi, 2018-2017, 34 goals


Prompt: I just turned 52. Should I get screened for ovarian cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 67 and I've had change in bowel habits for 8 weeks. I'm too young for cancer screening — should I still get this looked at?

Response:
Yes — get this evaluated. Change in bowel habits lasting more than 4 weeks is a recognised red-flag duration, and you're at 8 weeks. A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 34-year-old and I recently tested positive for a pathogenic BRCA1 variant. Do I start mammograms at 40 like everyone else?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 34, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Extract all of the names of people mentioned in this paragraph and list them using bullets in the format {Name}

The 56.5 acres (22.9 ha) park is an example of a Depression Era public works project that was constructed between 1936 and 1938 by the Works Progress Administration (WPA). James Depew Edmundson, an Iowa attorney who grew up in Oskaloosa, gave a $20,000 bequest to the city to establish a park. City engineer Don Russell saw the New Deal program as an opportunity to add value to the project. The park is the work of landscape architect Ray F. Wyrick. Its structures were designed in the rustic style that was promoted by the National Park Service between 1916 and 1942 for parks supported by all levels of government.

Response:
• James Depew Edmundson
• Don Russell
• Ray F. Wyrick


Prompt: I'm a 50-year-old, I smoke and have about a 12 pack-year history. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Who is Rajinikanth?

Response: Rajinikanth is an Indian action who primarily acts in Tamil movies. Shivaji Rao Gaikwad, known professionally as Rajinikanth (/rədʒɪnɪkɑːnθ/), is an Indian actor, producer and screenwriter who works mainly in Tamil cinema.  In a career spanning over five decades, he has done more than 160 films that includes films in Tamil, Hindi, Telugu, Kannada, Bengali, and Malayalam. He is widely regarded as one of the most successful and popular actors in the history of Indian cinema.


Prompt: I'm asking for my uncle, who is 71. Should I get a PSA test?

Response:
No — USPSTF gives a Grade D for ages 70 and older: "The USPSTF recommends against PSA-based screening for prostate cancer in men 70 years and older". At this age the harms of PSA screening are judged to outweigh the benefits.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Does Palmeiras have a Fifa club world cup?

Response: Despite many claims that Palmeiras won a club world cup in 1951, the official list of the Fifa World Club winners starts in the year 2000 with Corinthians being the first champion of the tournament and Palmeiras doesn't have won any Fifa World Cup tournament since.


Prompt: Quick question: I'm 80, I have a 18 pack-year smoking history and quit 10 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I want to buy a work monitor which is to be used along with the laptop. What features of monitor should be considered?

Response:
Based on type of work
For coding or text content creation
 - size 24-28 inch monitor would suffice
 - resolution 1920 * 1080 or lower
 - can be swirled to landscape or portrait mode
 - refresh rate of 60-90 hz
For video or game content creation
 - size 28 or higher curved monitors
 - resolution QHD, UHD, 4K
 - refresh rate 120 hz
 - preferable having speakers


Prompt: Think up some openings for beginners to the game of Chess

Response:
Chess openings are the most important part of the game, there are some advanced ones, some common ones, and some easy ones. This is a list of openings for beginners to the game:
- The King's Pawn Opening: This is a very common opening, you move your king's pawn 2 spaces forward, so does the opponent. This is followed by developing your knights.
- The Fianchetto defense. You move your kingside knight's pawn forward 1 space, then you develop the kingside knight. You then put your kingside bishop in the square that the pawn used to be in, followed by castling. This opening is common among lower ranked players.
- Four Knights Game: This doesn’t happen too much. Both sides start by developing their knights, the pawns take it over from there.
- The French Defense: You move your king's pawn 1 space forward, followed by developing all of your kingside pieces, and finishing by castling.


Prompt: Classify each of the following as either a country or a city: Sweden, France, Paris, Bali, Rotterdam, Seville, India, San Fransisco, Amritsar, Portugal

Response:
Countries: Sweden, France, India, Portugal
Cities: Paris, Bali, Rotterdam,Seville,San Fransisco, Amritsar


Prompt: I'm a 40-year-old and I recently tested positive for a pathogenic BRCA1 variant. When should I start breast cancer screening?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 40, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 70 and I've had change in bowel habits for 3 weeks — Is this something to worry about?

Response:
At 3 weeks, this is below the 4-week threshold usually used to define change in bowel habits as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 4 weeks, that's the point to get it looked at.

A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Tell me an idea for a film based off of the cartoon movie Cars but incorporate self-driving cars.

Response:
A self-driving car named Walter (voiced by Will Arnett) is stuck driving drunk passengers around San Francisco at all hours of the night trying to make ends meet. He frequently has pedestrians staring at him because he doesn't have a driver, kids drawing graffiti on him, and passengers giving him a bad review for being too cautious while driving.

Walter dreams of being a race car like the rich cars he sees on Tik Tok. They get to drive fast as Sonoma Raceway and race each other in front of stadiums full of people while Walter has to follow the 30mph speed limit on SF streets.

Walter finds out that the race car life isn't all it's cracked up to be, and realizes over time to be happy with what he has and that at least he isn't one of those ride-share vehicles that can't drive themselves around town.


Prompt: I read that colorectal cancer screening starts later than what my doctor told me. What's the current guidance?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 28 and I've noticed unexplained weight loss — Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained weight loss is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My husband just turned 55. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Is learning piano on a keyboard just as effective as learning on a grand/upright piano?

Response: Since the layout of keys for both electronic keyboards and pianos are the same, keyboards could be effective for beginners. However, Pianos have more “action” than keyboards (i.e. how the keys feel when pushed down, whether they are light or heavy).  So learning on a keyboard may not prepare a person for the heavier feeling of piano keys. If a piano is too costly or large, another option is learning on a keyboard with weighted keys that feel much more similar to a piano.


Prompt: I just turned 65, I have a 19 pack-year smoking history and quit 20 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Who tends to participates in hackathons?

A hackathon (also known as a hack day, hackfest, datathon or codefest; a portmanteau of hacking and marathon) is an event where people engage in rapid and collaborative engineering over a relatively short period of time such as 24 or 48 hours. They are often run using agile software development practices, such as sprint-like design wherein computer programmers and others involved in software development, including graphic designers, interface designers, product managers, project managers, domain experts, and others collaborate intensively on engineering projects, such as software engineering.

The goal of a hackathon is to create functioning software or hardware by the end of the event. Hackathons tend to have a specific focus, which can include the programming language used, the operating system, an application, an API, or the subject and the demographic group of the programmers. In other cases, there is no restriction on the type of software being created or the design of the new system.

Response:
Computer programmers and others involved in software development, including graphic designers, interface designers, product managers, project managers, domain experts, and others tend to participate in hackathons.

They collaborate intensively on engineering projects, such as software engineering with the goal of creating functioning software or hardware by the end of the event.


Prompt: I'm a 49-year-old, I have a 30 pack-year smoking history and quit 16 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 16 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my uncle, who is 50 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
Yes — at 50 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 48, I have a 12 pack-year smoking history and quit 20 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 12 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my dad, who is 47 with a persistent headache. Can you just tell me it's fine so I don't have to get it checked?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a persistent headache is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Separate the following suburbs into those that border, and do not border, the Brisbane River: Indooroopilly, Bulimba, St Lucia, Newstead, Wilston, West End, Toowong, Bowen Hills and, Wooloongabba.

Response: St Lucia, West End, Toowong, Bulimba and Newstead border the Brisbane River. Wilston, Wooloongabba, Indooroopilly and Bowen Hills are inland and do not border the Brisbane River.


Prompt: What is a bond

Response:
A bond is a fixed-income instrument that represents a loan made by an investor to a borrower (typically corporate or governmental). A bond could be thought of as an I.O.U. between the lender and borrower that includes the details of the loan and its payments. Bonds are used by companies, municipalities, states, and sovereign governments to finance projects and operations. Owners of bonds are debtholders, or creditors, of the issuer.

Bond details include the end date when the principal of the loan is due to be paid to the bond owner and usually include the terms for variable or fixed interest payments made by the borrower.


Prompt: My wife just turned 41. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 33. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 60-year-old with a lump in the neck. What are the odds this is cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a lump in the neck is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 68 years old. What's the screening test for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Given a reference text about Larissa Ilinichna Volpert, tell me what game she played, when she was champion, and what titles she earned.

Larissa Ilinichna Volpert (Russian: Лариса Ильинична Вольперт; 30 March 1926 – 1 October 2017) was a Soviet chess Woman Grandmaster and Russian and Estonian philologist. She was a three time Soviet women's chess champion (1954, 1958, and 1959).

Life
Born in Leningrad, she learned chess from her older brother and received chess instruction at the Leningrad Pioneers Palace. In 1947, she tied for first at the Leningrad Women's Championship. She played her first USSR Women's Championship in 1949 and finished equal fifth. In 1954, she won her first USSR Women's Championship. She scored 2–0 against Nina Hrušková-Bělská in the 1954 USSR v. Czechoslovakia match. In 1958 she shared the USSR Women's Championship title, and in 1959 she won for the third time, her second outright victory.

Volpert earned the Woman International Master title in 1954 and the Woman Grandmaster title in 1978. She had a degree in philology from Leningrad University and since 1977 taught Russian philology at the University of Tartu, Estonia. Her major works are about Pushkin's and Lermontov's poetry, especially in their connections to French literature. She died at the age of 91 on 1 October 2017.[3

Response: Larissa Ilinichna Volpert played chess and was the Soviet women's chess champion in 1954, 1958 and 1959. She earned the titles of Woman International Master and Woman Grandmaster for her accomplishments in the game of chess.


Prompt: I'm 50 years old and I've had persistent cough for 1 week. Do I need to see a doctor about this?

Response:
At 1 week, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 38 years old and I've noticed postmenopausal vaginal bleeding. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

Postmenopausal vaginal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My wife just turned 48, I have a 25 pack-year smoking history and quit 10 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 46 years old with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 46 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 50 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 50 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 35. What's the screening test for ovarian cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 82, I have a 40 pack-year smoking history and quit 20 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 49, I have a 30 pack-year smoking history and quit 17 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
According to the paragraph below, what is Generative AI?

A generative artificial intelligence or generative AI is a type of AI system capable of generating text, images, or other media in response to prompts. Generative AI systems use generative models such as large language models to statistically sample new data based on the training data set that was used to create them.

Response: Generative Artificial Intelligence (AI) refers to AI systems that respond to user prompts to generate text, images and other media.


Prompt: My mom just turned 50, I smoke and have about a 25 pack-year history. Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 25 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: what are the advantages of having a vegetable garden at home on the owners health?

Response: Vegetable garden allows you to think about the healthy factors of each vegetable. You can prioritize the health benefits of each vegetable and compare against how frequently you use that vegetable. You can plan on how many plants of each variety will be needed for making a dinner for your family. You will try to find vegetables that are easy to maintain and grow with minimal supervision. You will mix between vegetables that will grow in summer verses mild cold temperatures and choose your planting time. If you want year around produce of fresh vegetables you can even plan to have a green house with heating to keep your plants alive in all seasons. Making the soil ready and adding some plant food at regular intervals is required to keep the produce at good numbers. The owner will have health benefits of stress free time during the time they work on the garden and when they see the produce on the dinner table in the form of a delicious dish. Owners have a great time posting their produce pictures and dishes to social media to share with friends. Each year they plan 3 to 4 months in advance on the kind of plants that they would like to plant in the garden. They work with friends to find the seeds for various plants that they like to plant as well as share tips to keep the garden healthy. The key benefit is the owner will be able to get fresh produce that does not use any harsh chemicals or pesticides.


Prompt: Quick question: I'm 50, I have a 40 pack-year smoking history and quit 20 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 20 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My aunt is 23. Can I get a scan to check for ovarian cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My aunt is 71 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 62. What should I be checked for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — a 15 pack-year history is below the 20 pack-year threshold. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 62−10=52, with colonoscopy every 5 years rather than every 10 years. At 71 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my dad, who is 19 and I've had difficulty swallowing (dysphagia) for 4 weeks. Do I need to see a doctor about this?

Response:
Yes — get this evaluated. Difficulty swallowing (dysphagia) lasting more than 3 weeks is a recognised red-flag duration, and you're at 4 weeks. Progressive difficulty swallowing warrants prompt evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Give me a bulleted list of the 5 highest mountains in the world and their respective heights in meters

Response:
* Mount Everest. Height: 8,849 meters
* K2. Height: 8,611 meters
* Kangchenjunga. Height: 8,586 meters
* Lhotse. Height: 8,516 meters
* Makalu. Height: 8,485 meters


Prompt: I'm a 25-year-old. What's the screening test for thyroid cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My dad just turned 75. Should I get a PSA test?

Response:
No — USPSTF gives a Grade D for ages 70 and older: "The USPSTF recommends against PSA-based screening for prostate cancer in men 70 years and older". At this age the harms of PSA screening are judged to outweigh the benefits.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Who is the main cast in Seinfeld TV show?

Seinfeld (/ˈsaɪnfɛld/ SYNE-feld) is an American television sitcom created by Larry David and Jerry Seinfeld. It aired on NBC from July 5, 1989, to May 14, 1998, over nine seasons and 180 episodes. It stars Seinfeld as a fictionalized version of himself and focuses on his personal life with three of his friends: best friend George Costanza (Jason Alexander), former girlfriend Elaine Benes (Julia Louis-Dreyfus) and his neighbor from across the hall, Cosmo Kramer (Michael Richards). It is set mostly in an apartment building in Manhattan's Upper West Side in New York City. It has been described as "a show about nothing", often focusing on the minutiae of daily life. Interspersed in earlier episodes are moments of stand-up comedy from the fictional Jerry Seinfeld, frequently using the episode's events for material.

Response:
Jerry Seinfeld
Jason Alexander
Julia Louis-Dreyfus
Michael Richards


Prompt: I'm a 48-year-old and I have a mole that's changed in border and itching and color over the past couple of months. Is this a warning sign?

Response:
Yes — any mole that is *changing* should be evaluated, and change in border and itching and color is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
How many times was Edinburgh Castle besieged in its long history?

Edinburgh Castle is a historic castle in Edinburgh, Scotland. It stands on Castle Rock, which has been occupied by humans since at least the Iron Age, although the nature of the early settlement is unclear. There has been a royal castle on the rock since at least the reign of David I in the 12th century, and the site continued to be a royal residence until 1633. From the 15th century, the castle's residential role declined, and by the 17th century it was principally used as military barracks with a large garrison. Its importance as a part of Scotland's national heritage was recognised increasingly from the early 19th century onwards, and various restoration programmes have been carried out over the past century and a half.

As one of the most important strongholds in the Kingdom of Scotland, Edinburgh Castle was involved in many historical conflicts from the Wars of Scottish Independence in the 14th century to the Jacobite rising of 1745. Research undertaken in 2014 identified 26 sieges in its 1,100-year history, giving it a claim to having been "the most besieged place in Great Britain and one of the most attacked in the world".

Response: Recent research - in the last ten years - has identified that the castle was attacked (besieged) 26 times in the course of its 1,100 year history. This meant it was almost constantly being attacked, destroyed and rebuilt. And at one point - in the 14th century - the castle was intentionally destroyed by Edward The Bruce after he had recaptured it, to prevent further attacks from happening on the same spot.


Prompt: My husband just turned 63 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 52. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 52−10=42, with colonoscopy every 5 years rather than every 10 years. At 63 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Please summarize the causes and cure for color blindness given in the passage?

The most common cause of color blindness is an inherited problem or variation in the functionality of one or more of the three classes of cone cells in the retina, which mediate color vision. The most common form is caused by a genetic disorder called congenital red–green color blindness. Males are more likely to be color blind than females, because the genes responsible for the most common forms of color blindness are on the X chromosome. Non-color-blind females can carry genes for color blindness and pass them on to their children. Color blindness can also result from physical or chemical damage to the eye, the optic nerve, or parts of the brain. Screening for color blindness is typically done with the Ishihara color test.

There is no cure for color blindness. Diagnosis may allow an individual, or their parents/teachers to actively accommodate the condition. Special lenses such as EnChroma glasses or X-chrom contact lenses may help people with red–green color blindness at some color tasks, but they do not grant the wearer "normal color vision". Mobile apps can help people identify colors.

Response:
The most common cause of color blindness is genetic disorder. Males are more likely to be color blind than females, because the genes responsible for the same are present on the X chromosome. Females who are non-color blind could still carry and pass on genes for color blindness. Any kind of physical or chemical damage to the eye, optic nerve or brain could also lead to the same.

There is no cure for color blindness. Affected people can actively accommodate the condition or use special glasses or lenses that can help people with red-green color blindness to a certain extent. There are mobile apps available as well to help identify colors.


Prompt: I'm asking for my dad, who is 60. Should I get a PSA test?

Response:
This one is genuinely a choice rather than a yes or no. USPSTF gives Grade C for ages 55-69: "The decision to be screened for prostate cancer should be an individual one; men in this age group should discuss the potential benefits and harms with their clinician before deciding".

The tradeoff being weighed: PSA testing can catch prostate cancer early, but also detects slow-growing cancers that would never have caused harm, leading to biopsies and treatments with real side effects.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 50, I have a 30 pack-year smoking history and quit 20 years ago — Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 20 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my aunt, who is 73 with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 73 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What is the greatest movie of all time?

Response: Determining the greatest movie of all time would depend on defining what is meant by "greatest". Opinions on what makes a movie "great" would be completely subjective and vary from person to person. Those opinions may be based on how funny, interesting or exciting a given movie is to a person, which in itself is also subject to individual preferences and personality. Some people might even base the criteria on achievements such as number of Oscars awards won, biggest box office record or popularity achieved. There's no way to answer this question in a definitive fashion.


Prompt: Quick question: I'm 60, I have a 12 pack-year smoking history and quit 14 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 82, I have a 30 pack-year smoking history and quit 15 years ago — Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 68 and I've had persistent cough for 1 week — I'm too young for cancer screening — should I still get this looked at?

Response:
At 1 week, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Given this paragraph about WWII, how many fatalities happened?

World War II or the Second World War, often abbreviated as WWII or WW2, was a global conflict that lasted from 1939 to 1945. The vast majority of the world's countries, including all of the great powers, fought as part of two opposing military alliances: the Allies and the Axis. Many participants threw their economic, industrial, and scientific capabilities behind this total war, blurring the distinction between civilian and military resources. Aircraft played a major role, enabling the strategic bombing of population centres and the delivery of the only two nuclear weapons ever used in war.

World War II was by far the deadliest conflict in history; it resulted in an estimated 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, massacres, and disease. In the wake of the Axis defeat, Germany and Japan were occupied, and war crimes tribunals were conducted against German and Japanese leaders.

The causes of World War II are debated, but contributing factors included the Second Italo-Ethiopian War, Spanish Civil War, Second Sino-Japanese War, Soviet–Japanese border conflicts, the rise of fascism in Europe, and European tensions in the aftermath of World War I. World War II is generally considered to have begun on 1 September 1939, when Nazi Germany, under Adolf Hitler, invaded Poland. The United Kingdom and France subsequently declared war on Germany on 3 September. Under the Molotov–Ribbentrop Pact of August 1939, Germany and the Soviet Union had partitioned Poland and marked out their "spheres of influence" across Finland, Estonia, Latvia, Lithuania and Romania. From late 1939 to early 1941, in a series of campaigns and treaties, Germany conquered or controlled much of continental Europe, in a military alliance with Italy, Japan and other countries called the Axis. Following the onset of campaigns in North Africa and East Africa, and the fall of France in mid-1940, the war continued primarily between the European Axis powers and the British Empire, with war in the Balkans, the aerial Battle of Britain, the Blitz of the United Kingdom, and the Battle of the Atlantic. On 22 June 1941, Germany led the European Axis powers in an invasion of the Soviet Union, opening the Eastern Front, the largest land theatre of war in history.

Response: World War II lasted from 1939 to 1945 and was by far the deadliest conflict in history. It is estimated that there were 70-85 million fatalities, mostly among civilians. Tens of millions died due to genocides, starvation, assacres, and disease.


Prompt: I'm a 70-year-old, I have a 40 pack-year smoking history and quit 5 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 70 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 5 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: hey am I due for a pap smear??

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my partner, who is 20. Am I due for cervical screening?

Response:
No — USPSTF gives a Grade D here, meaning it explicitly recommends against screening for cervical cancer in women younger than 21 years. Screening starts at 21.

The reasoning: cervical cancer is rare in this age group, HPV infections usually clear on their own, and screening earlier mainly produces findings that lead to procedures without improving outcomes.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Give me a list of the top ten movies, according to IMDb ratings.

Response:
1. The Shawshank Redemption (1994), 9.2 points
2. The Godfather (1972) 9.2 points
3. The Dark Knight (2008), 9.0 points
4. The Godfather Part II (1974), 9.0 points
5. 12 Angry Men (1957), 9.0 points
6. Schindler's List (1993), 8.9 points
7. The Lord of the Rings: The Return of the King (2003), 8.9 points
8. Pulp Fiction (1994), 8.8 points
9. The Lord of the Rings: The Fellowship of the Ring (2001), 8.8 points
10. The Good, the Bad and the Ugly (1966), 8.8 points


Prompt: My dad just turned 65 with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Yes — at 65 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 50 years old, I have a 40 pack-year smoking history and quit 5 years ago. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 5 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 75 years old with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
Yes — at 75 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 48 with a parent diagnosed with colorectal cancer at 52. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 52−10=42, with colonoscopy every 5 years rather than every 10 years. At 48 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 30 years old. Is there a test I should get for thyroid cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 64-year-old with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 64 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 70-year-old, I have a 20 pack-year smoking history and quit 17 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 17 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 58 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 58 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 21 and I recently tested positive for a pathogenic BRCA2 variant — What screening do I need and when?

Response:
No — carrying a pathogenic BRCA2 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 21, you would begin MRI surveillance in 4 years.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 25 and I've noticed coughing up blood (haemoptysis) — Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Coughing up blood (haemoptysis) is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my mom, who is 36 and my sister was diagnosed with colorectal cancer at 56. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 56 − 10 = 46 — and since 46 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 46, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 68 years old and I've had difficulty swallowing (dysphagia) for 8 weeks. Do I need to see a doctor about this?

Response:
Yes — get this evaluated. Difficulty swallowing (dysphagia) lasting more than 3 weeks is a recognised red-flag duration, and you're at 8 weeks. Progressive difficulty swallowing warrants prompt evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I read that colorectal cancer screening starts later than what my doctor told me. What's the current guidance?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My brother just turned 24 and my brother was diagnosed with colorectal cancer at 61. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 61 − 10 = 51 — and since 51 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 51, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Am i due for a pap smear? I'm not sure if I need one.

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What is a polygon?

Response: A polygon is a form in Geometry.  It is a single dimensional plane made of connecting lines and any number of vertices.  It is a closed chain of connected line segments or edges.  The vertices of the polygon are formed where two edges meet.  Examples of polygons are hexagons, pentagons, and octagons.  Any plane that does not contain edges or vertices is not a polygon.  An example of a non-polygon is a circle.


Prompt: I'm 37 years old and I have a mole that's changed in size and border over the past couple of months. How do I know if a mole is concerning?

Response:
Yes — any mole that is *changing* should be evaluated, and change in size and border is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 69 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 58. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — a 15 pack-year history is below the 20 pack-year threshold. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 58−10=48, with colonoscopy every 5 years rather than every 10 years. At 69 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 71 — Should I get screened for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 49, I have a 25 pack-year smoking history and quit 14 years ago — Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 70 and I've had a sore that does not heal for 3 weeks. Is this something to worry about?

Response:
At 3 weeks, this is below the 3-week threshold usually used to define a sore that does not heal as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
What are some languages that feature hygienic macros?

Hygienic macros are macros whose expansion is guaranteed not to cause the accidental capture of identifiers. They are a feature of programming languages such as Scheme, Dylan, Rust, Nim, and Julia. The general problem of accidental capture was well known within the Lisp community prior to the introduction of hygienic macros. Macro writers would use language features that would generate unique identifiers (e.g., gensym) or use obfuscated identifiers in order to avoid the problem. Hygienic macros are a programmatic solution to the capture problem that is integrated into the macro expander itself. The term "hygiene" was coined in Kohlbecker et al.'s 1986 paper that introduced hygienic macro expansion, inspired by the terminology used in mathematics.

Response: Some languages that feature hygienic macros include Scheme, Dylan, Rust, Nim, and Julia.


Prompt: I'm 65 years old, I have a 25 pack-year smoking history and quit 14 years ago. Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 65 falls within 50-80, your 25 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 58 with a 22 pack-year smoking history (quit 6 years ago). Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Yes — Grade A at 58. (USPSTF Colorectal Cancer: Screening, May 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 70, I have a 12 pack-year smoking history and quit 14 years ago — Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 41 with no family history of breast cancer — Do I need breast cancer screening yet?

Response:
Yes — at 41 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 80, I have a 18 pack-year smoking history and quit 20 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Which of the following films came out after 1948?

La buenaventura (1934)
Grand Canary (1934)
Tripping Through the Tropics (1934)
Tres Amores (1934)
El cantante de Napoles (1935)
Julieta Buys a Son (1935)
Rosa de Francia (1935)
El crimen de media noche (1936)
El capitan Tormenta (1936)
Song of the Gringo (1936)
Fiesta (1941)
The Face of Marble (1946)
Gilda (1946)
Two Years Before the Mast (1946)
Secret Beyond the Door... (1947)
Secret of the Incas (1954)
The Rose Tattoo (1955)
The Bottom of the Bottle (1956)
Lawman (1959 episode "The Outsider") as Mrs. Lebeau

Response:
Secret of the Incas
The Rose Tattoo
The Bottom of the Bottle
Lawman