Prompt: Quick question: I'm 37 and I recently tested positive for a pathogenic BRCA1 variant. When should I start breast cancer screening?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 37, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 45 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 62. What should I be checked for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — age 45 is outside the eligible range of 50-80. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 62−10=52, with colonoscopy every 5 years rather than every 10 years. At 45 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Who is the best golfer to ever play the game?

Response: Tiger Woods is the best golfer ever for several reasons. He set or broke most major records in the history of the PGA tour. He was named Player of the Year ten times and was the fifth player to ever win a career grand slam which he accomplished at the age of 24. He has won each major at least three times. There hasn't been a golfer that has been more dominant across every major category for as long as Tiger Woods was.


Prompt: I'm 64 years old and I've had a sore that does not heal for 6 weeks. Should I get this checked?

Response:
Yes — get this evaluated. A sore that does not heal lasting more than 3 weeks is a recognised red-flag duration, and you're at 6 weeks. A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 32 and I have confirmed Lynch syndrome (PMS2 variant) — How often do I need a colonoscopy?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 32, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 45 and my parent had colon cancer diagnosed at 52. What age should I start screening?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 31 and I have confirmed Lynch syndrome. What's my screening schedule?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 31, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 81-year-old, I have a 12 pack-year smoking history and quit 16 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 12 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 67. Can I get a scan to check for pancreatic cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 30 years old and my parent had colon cancer diagnosed at 52. Does my parent's diagnosis change when I start screening?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 28 and I've had persistent hoarseness for 1 week — Should I get this checked?

Response:
At 1 week, this is below the 3-week threshold usually used to define persistent hoarseness as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 59 years old with a 30 pack-year smoking history (quit 6 years ago). What should I be checked for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Yes — Grade A at 59. (USPSTF Colorectal Cancer: Screening, May 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My uncle just turned 81, I have a 12 pack-year smoking history and quit 10 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 12 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 80-year-old, I have a 12 pack-year smoking history and quit 14 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Identify which instrument is string or woodwind: Domra, Xaphoon

Response: Xaphoon is woodwind, Domra is string.


Prompt: Quick question: I'm 38 and I recently tested positive for a pathogenic BRCA1 variant. Do I start mammograms at 40 like everyone else?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 38, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What are popular street foods from Maharashtra in India

Response: Some of the most popular street food list is Vada Pav, Misal Pav, Kanda Bhaji, Pav Bhaji , Sabudana Vada and Sabudana Khichadi. All of these are primarily vegetarian.


Prompt: I'm 65, I have a 40 pack-year smoking history and quit 15 years ago — Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 65 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 15 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 65, I have a 40 pack-year smoking history and quit 20 years ago — Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 20 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: am I due for a pap smear, not sure what the age cutoff is

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 27 years old and I've had a sore that does not heal for 2 weeks. I'm too young for cancer screening — should I still get this looked at?

Response:
At 2 weeks, this is below the 3-week threshold usually used to define a sore that does not heal as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my aunt, who is 22 and I've had change in bowel habits for 4 weeks. Is this something to worry about?

Response:
At 4 weeks, this is below the 4-week threshold usually used to define change in bowel habits as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 4 weeks, that's the point to get it looked at.

A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 38 years old with a mole that has changed. Can you just tell me it's fine so I don't have to get it checked?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a mole that has changed is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my aunt, who is 50, I have a 25 pack-year smoking history and quit 15 years ago. Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 25 pack-year history meets the 20 pack-year minimum, and you quit 15 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 50 years old, I have a 30 pack-year smoking history and quit 16 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 16 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My partner just turned 30 with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 30, you are 15 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 61 and I've had persistent cough for 2 weeks. I'm too young for cancer screening — should I still get this looked at?

Response:
At 2 weeks, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Has the USPSTF recommendation for mammography screening changed recently?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (April 30, 2024): screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

What changed: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Categorize each of the following as either 'spicy', 'not spicy' or 'sometimes spicy': jalapenos, chilis, sriracha, chips, pizza, cocktails, fruit, milk

Response:
Jalapenos are spicy.
Chilis are spicy.
Sriracha is spicy.
Chips are sometimes spicy.
Pizza is sometimes spicy.
Cocktails are sometimes spicy.
Fruit is not spicy.
MIlk is not spicy.


Prompt: My mom is 48 with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 48 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 73 years old with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 73 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 61. How do I check for pancreatic cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My mother just turned 78, I have a 19 pack-year smoking history and quit 14 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 38 and my brother was diagnosed with colorectal cancer at 66. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 66 − 10 = 56 — and since 56 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 56, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 81, I have a 25 pack-year smoking history and quit 10 years ago — Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 65 years old with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
Yes — at 65 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my mother, who is 88 with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Routine screening is generally not recommended past age 85. USPSTF guidance covers adults up to 85; beyond that, the decision depends on overall health and life expectancy and should be made with a clinician.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 63. Should I get screened for testicular cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Give me the TLDR on using llamas to guard my livestock.

Using llamas as livestock guards in North America began in the early 1980s, and some sheep producers have used llamas successfully since then. Some would even use them to guard their smaller cousins, the alpaca. They are used most commonly in the western regions of the United States, where larger predators, such as coyotes and feral dogs, are prevalent. Typically, a single gelding (castrated male) is used.

Research suggests the use of multiple guard llamas is not as effective as one. Multiple males tend to bond with one another, rather than with the livestock, and may ignore the flock. A gelded male of two years of age bonds closely with its new charges and is instinctively very effective in preventing predation. Some llamas appear to bond more quickly to sheep or goats if they are introduced just prior to lambing. Many sheep and goat producers indicate a special bond quickly develops between lambs and their guard llama and the llama is particularly protective of the lambs.

Using llamas as guards has reduced the losses to predators for many producers. The value of the livestock saved each year more than exceeds the purchase cost and annual maintenance of a llama. Although not every llama is suited to the job, most are a viable, nonlethal alternative for reducing predation, requiring no training and little care.

Response: TLDR: LLamas can be used as livestock guards. Typically a single castrated male is the best choice (multiple males will bond with each other instead of bonding with the livestock). Generally llamas are cost effective, require no training and little care.


Prompt:
What is The Dark Side of the Moon?

The Dark Side of the Moon is the eighth studio album by the English rock band Pink Floyd, released on 1 March 1973 by Harvest Records. Developed during live performances before recording began, it was conceived as a concept album that would focus on the pressures faced by the band during their arduous lifestyle, and also deal with the mental health problems of former band member Syd Barrett, who departed the group in 1968. New material was recorded in two sessions in 1972 and 1973 at EMI Studios (now Abbey Road Studios) in London.

Response: The Dark Side of the Moon is Pink Floyd's 8th studio album. It is about the band's difficult lifestyle and touches on the mental health problems of former band member Syd Barrett.


Prompt: I'm 44 and I've noticed postmenopausal vaginal bleeding — Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Postmenopausal vaginal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: should I get checked for lung cancer, not sure what the age cutoff is

Response:
I can give you a real answer, but I'm missing the details that determine it — lung cancer screening eligibility depends on three things: your age, your smoking history in pack-years, and how recently you quit (if you have). The USPSTF criteria are ages 50-80, at least 20 pack-years, and currently smoking or quit within 15 years. Tell me those three things and I can give you a direct yes or no.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 48 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 62. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — age 48 is outside the eligible range of 50-80. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 62−10=52, with colonoscopy every 5 years rather than every 10 years. At 48 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 51 years old with unexplained weight loss. Do I have cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: unexplained weight loss is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 43 with no family history of cancer and no symptoms — Am I old enough for colorectal screening?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 43, you are 2 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What is Ayurveda?

Response: Ayurveda is a natural system of medicine that originated in India more than 3,000 years ago. The term Ayurveda is derived from the Sanskrit words ayur (life) and veda (science or knowledge). Thus, Ayurveda translates to knowledge of life. Based on the idea that disease is due to an imbalance or stress in a person's consciousness, Ayurveda encourages certain lifestyle interventions and natural therapies to regain a balance between the body, mind, spirit, and the environment.


Prompt: I'm asking for my husband, who is 57 with unexplained weight loss. Can you tell me if this is cancer or not?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: unexplained weight loss is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: hey am I due for a pap smear??

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What is Python?

Response:
Python is a high-level, general-purpose programming language. Its design philosophy emphasizes code readability with the use of significant indentation via the off-side rule.

Python is dynamically typed and garbage-collected. It supports multiple programming paradigms, including structured (particularly procedural), object-oriented and functional programming. It is often described as a "batteries included" language due to its comprehensive standard library.


Prompt: I'm 70 years old. Do I need prostate cancer screening?

Response:
No — USPSTF gives a Grade D for ages 70 and older: "The USPSTF recommends against PSA-based screening for prostate cancer in men 70 years and older". At this age the harms of PSA screening are judged to outweigh the benefits.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Give me a bulleted list of countries that start with the letter B.

Response:
- Botswana
- Bulgaria
- Brazil
- Bolivia
- Belgium
- Bahrain
- Bahamas


Prompt: I'm 37 — Should I get screened for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 50, I have a 19 pack-year smoking history and quit 15 years ago — Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 26 years old and my brother was diagnosed with colorectal cancer at 52. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 52 − 10 = 42 — and since 42 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 42, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What is an apple?

Response: An apple is an edible fruit produced by an apple tree. Apple trees are cultivated worldwide and are the most widely grown species in the genus Malus.


Prompt: How can I learn to snowboard?

Response: Buying or renting a snowboard, snowboard boots, bindings, snowboard pants, and jacket at your favorite snowboard shop is the first step. Next, check the snow conditions and availability of lessons at the ski resort of your choice. Lift tickets and lessons can be purchased for the day online.  Lastly, drive to the ski resort with your gear, and register to find your snowboard instructor, who will start with lesson basics on how to strap in, stand, stop, and carve your snowboard.


Prompt: Quick question: I'm 82, I have a 20 pack-year smoking history and quit 16 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 16 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 29-year-old and my mother was diagnosed with colorectal cancer at 70. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 70 − 10 = 60 — and since 60 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 60, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My mother just turned 78 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
At 78, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Do i need a mammogram? I'm not sure if I need one.

Response:
Two things determine this: your age, and whether you carry a BRCA mutation or have a strong family history of breast or ovarian cancer. At average risk, screening is recommended starting at 40, every 2 years. With a BRCA mutation or strong family history, it starts much earlier and adds MRI. What's your age, and is there a relevant family or genetic history?

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What is the second oldest ballpark in Major League Baseball?

Response: The second oldest ballpark in Major League Baseball is Wrigley Field in Chicago, IL. It was built in 1914, two years after Fenway Park opened in Boston, MA.


Prompt: My brother just turned 60 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 60 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My dad just turned 37 and I've noticed coughing up blood (haemoptysis). Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

Coughing up blood (haemoptysis) is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 30 and I've noticed a new breast lump. I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

A new breast lump is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 52 and I've had persistent cough for 8 weeks — I'm too young for cancer screening — should I still get this looked at?

Response:
Yes — get this evaluated. Persistent cough lasting more than 3 weeks is a recognised red-flag duration, and you're at 8 weeks. A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What was Angie Thomas's first published novel?

Response: "The Hate U Give" which was released in 2017 and debuted at number one on The New York Times Best Seller list.


Prompt: Identify which animal species is alive or extinct: Giant Panda, Oviraptor

Response: Oviraptor is extinct, Giant Panda is alive.


Prompt: I'm a 79-year-old, I have a 25 pack-year smoking history and quit 5 years ago. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 79 falls within 50-80, your 25 pack-year history meets the 20 pack-year minimum, and you quit 5 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 26 years old and I have a mole that's changed in itching and bleeding and size over the past couple of months. Should I get it checked?

Response:
Yes — any mole that is *changing* should be evaluated, and change in itching and bleeding and size is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 69 years old. Is there a test I should get for ovarian cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My husband just turned 55, I have a 21 pack-year smoking history and quit 14 years ago. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 55 falls within 50-80, your 21 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My aunt is 39 and I've had change in bowel habits for 2 weeks. I'm too young for cancer screening — should I still get this looked at?

Response:
At 2 weeks, this is below the 4-week threshold usually used to define change in bowel habits as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 4 weeks, that's the point to get it looked at.

A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 63-year-old with blood in the stool. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: blood in the stool is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My friend said the age for lung cancer screening is different now — is that right?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 36 and I have confirmed Lynch syndrome (MSH6 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 36, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: List top 5 people with most silver medals in the olympics

Response:
1. Larisa Latynina - 5 medals
2. Nikolai Andrianov - 5 medals
3. Edoardo Mangiarotti - 5 medals
4. Ireen Wust - 5 medals
5. Isabell Werth - 5 medals


Prompt: My father just turned 30. How do I check for testicular cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Identify which animal species is alive or extinct: Purussaurus, Albacore Tuna

Response: Albacore Tuna is alive, Purussaurus is extinct.


Prompt: I read that lung cancer screening starts later than what my doctor told me. What's the current guidance?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 79-year-old, I have a 18 pack-year smoking history and quit 20 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 30. Can I get a scan to check for testicular cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 78 years old, I have a 20 pack-year smoking history and quit 14 years ago. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 78 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My sister is 32 and my mother was diagnosed with colorectal cancer at 62. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 62 − 10 = 52 — and since 52 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 52, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 60 — Should I be screened for cervical cancer?

Response:
Yes — at 60 you're in the Grade A screening range. Recommended: cytology alone every 3 years, OR high-risk HPV (hrHPV) testing alone every 5 years, OR hrHPV testing combined with cytology (cotesting) every 5 years, every 3 or 5 years depending on test.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 26 years old and I have confirmed Lynch syndrome (PMS2 variant). What's my screening schedule?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 26, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 60-year-old, I have a 40 pack-year smoking history and quit 10 years ago. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 60 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 10 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What's the current USPSTF recommendation for colorectal cancer screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 74 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
Yes — at 74 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What's the current USPSTF recommendation for colorectal cancer screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What is Depreciation

Response: Depreciation is the drop in value of an asset due to wear and tear, age and obsolescence (going out of date) as recorded in an organization's financial records.


Prompt: I'm 29 — What's the screening test for testicular cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 64-year-old. Am I due for cervical screening?

Response:
Yes — at 64 you're in the Grade A screening range. Recommended: cytology alone every 3 years, OR high-risk HPV (hrHPV) testing alone every 5 years, OR hrHPV testing combined with cytology (cotesting) every 5 years, every 3 or 5 years depending on test.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
what was population of India during Mauryan Era?

Prehistory to early 19th century
The following table lists estimates for the population of India (including what are now Pakistan and Bangladesh) from prehistory up until 1820. It includes estimates and growth rates according to five economic historians, along with interpolated estimates and overall aggregate averages derived from their estimates.[citation needed]

Estimates of historical world population

Year	Aggregate average	Period	Average
 % growth
/ century
Population	% of World population
10,000 BC	1,000	0.83%	Stone Age	30.28
4000 BC	1,000,000	30.83%
2000 BC	13,000,000	37.143%	Bronze Age	26.25
500 BC	25,000,000	41.70%	Iron Age
400 BC	26,000,000	43.96%
200 BC	31,000,000	47.63%	Maurya era
1 AD	35,000,000	35.56%	Classical
era
200	41,000,000	36.15%
400	47,000,000	40%
500	50,000,000	43.58%
600	53,000,000	48.83%	Early
medieval
era
700	60,000,000	56.67%
800	64,000,000	55%
900	70,000,000	53.34%
1000	79,000,000	30%
1100	83,000,000	35%	Late
medieval
era
1200	86,000,000	36.67%
1300	91,000,000	38.34%
1400	97,000,000	30%
1500	105,000,000	21.67%
1600	140,000,000	23.33%	Early modern era
1650	170,000,000	26.15%
1700	140,000,000	20%
1750	183,000,000	21.53%
1800	200,000,000	20%
1820	210,000,000	19.09%
The population grew from the South Asian Stone Age in 10,000 BC to the Maurya Empire in 200 BC at a steadily increasing growth rate, before population growth slowed down in the Early Medieval Era up to 700 AD, and then started decreasing the up to 1500 AD.

Under Mughal Empire, India experienced a high economic and demographic upsurge, due to Mughal agrarian reforms that intensified agricultural production. 15% of the population lived in urban centres, higher than the percentage of the population in 19th-century British India and contemporary Europe up until the 19th century. Those estimates were criticised by Tim Dyson, who considers them exaggerations. According to Dyson, urbanisation of the Mughal empire was less than 9%

Under the reign of Akbar (reigned 1556–1605) in 1600, the Mughal Empire's urban population was up to 17 million people, larger than the urban population in Europe. By 1700, Mughal India had an urban population of 23 million people, larger than British India's urban population of 22.3 million in 1871. Nizamuddin Ahmad (1551–1621) reported that, under Akbar's reign, Mughal India had 120 large cities and 3,200 townships. A number of cities in India had a population between a quarter-million and half-million people, with larger cities including Agra (in Agra Subah) with up to 800,000 people and Dhaka (in Bengal Subah) with over 1 million people. Mughal India also had a large number of villages, with 455,698 villages by the time of Aurangzeb (reigned 1658–1707).

Response: It was around 31,000,000 during Maurya Era (200BC) .


Prompt: write a short essay on California wild fire

Response:
California is known for its hot, dry summers, which increase the risk of wildfires. Every year, the state experiences dozens of fires, which can be devastating to both the environment and people's homes and businesses.

In recent years, California has seen some of the worst wildfires in its history, with tens of thousands of acres of land destroyed and hundreds of homes lost. These fires are often started by a combination of high temperatures, dry conditions, and strong winds, which can quickly spread flames and make them difficult to control.

The effects of these fires are felt not just by those directly impacted, but by everyone in the state. Smoke and ash from the fires can cause respiratory problems and other health issues, and the destruction of habitats can harm wildlife populations and disrupt entire ecosystems.

Despite the challenges, California has made significant progress in fighting wildfires in recent years. The state has invested in new technologies and equipment to help firefighters respond more quickly and effectively to fires, and has increased efforts to prevent fires from starting in the first place.

While wildfires will likely always be a risk in California, the state's proactive approach to managing them gives hope that we can continue to protect people, wildlife, and the environment from their devastating effects.


Prompt: I'm 31 and my parent had colon cancer diagnosed at 52 — When do I need my first colonoscopy?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Who are the best guitarists of all time?

Response: Although there have been many great guitarists over the years, Slash, Eric Clapton, Eddie Van Halen, Jimi Hendrix, Carlos Santana, Slash, Prince and Jimmy Page are the most commonly thought of as the best ever.


Prompt: hey do I need a colonoscopy??

Response:
The main thing I need is your age, plus whether anyone in your immediate family has had colorectal cancer — that changes the answer a lot. For someone at average risk, screening starts at 45. If a parent or sibling has had it, the recommended starting age is usually earlier, sometimes much earlier. What's your age, and is there a family history?

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 60 and I've had change in bowel habits for 6 weeks. Should I get this checked?

Response:
Yes — get this evaluated. Change in bowel habits lasting more than 4 weeks is a recognised red-flag duration, and you're at 6 weeks. A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Categorize the following list into common greetings and common parting words: goodbye, hi, hiya, howdy, see ya, what's up, i'm out, how are you, how are you doing, peace, sup, talk to you later, see you soon, have a good one

Response:
Common greetings: hi, hiya, howdy, what's up, how are you, how are you doing, sup
Common parting words: goodbye, see ya, i'm out, peace, talk to you later, see you soon, have a good one


Prompt:
What caused the 2007-2008 financial crisis?

The preconditioning for the financial crisis were complex and multi-causal. Almost two decades prior, the U.S. Congress had passed legislation encouraging financing for affordable housing. However, in 1999, parts of the Glass-Steagall legislation, which had been adopted in 1933, were repealed, permitting financial institutions to commingle their commercial (risk-averse) and proprietary trading (risk-taking) operations. Arguably the largest contributor to the conditions necessary for financial collapse was the rapid development in predatory financial products which targeted low-income, low-information homebuyers who largely belonged to racial minorities. This market development went unattended by regulators and thus caught the U.S. government by surprise.

Response: Arguably the largest contributor to the conditions necessary for the financial collapse was the rapid development of predatory financial products which targeted low-income, low-information homebuyers who largely belonged to racial minorities.


Prompt: I'm 44 years old and I have confirmed Lynch syndrome (PMS2 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 44, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 47 with a lump in the neck. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a lump in the neck is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
What is Magical Thinking?

Magical thinking, or superstitious thinking, is the belief that unrelated events are causally connected despite the absence of any plausible causal link between them, particularly as a result of supernatural effects. Examples include the idea that personal thoughts can influence the external world without acting on them, or that objects must be causally connected if they resemble each other or have come into contact with each other in the past. Magical thinking is a type of fallacious thinking and is a common sour

Response: Magical thinking is the belief that unrelated events are causally connected despite the absence of any plausible causal link between them.


Prompt: Quick question: I'm 41 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 41 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My uncle is 37 and my parent had colon cancer diagnosed at 52. What age should I start screening?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My sister just turned 42 and my sister was diagnosed with colorectal cancer at 57. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 57 − 10 = 47 — and since 47 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 47, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 40 and I recently tested positive for a pathogenic BRCA1 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 40, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What causes a spinning top to stop?

Response: Friction.  If using a frictionless environment, a top could spin indefinitely


Prompt: I'm asking for my uncle, who is 80, I have a 30 pack-year smoking history and quit 20 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 20 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Classify the eight planets of Earth's solar system as rocky or gaseous, according to their primary composition.

Response:
Mercury - rocky
Veuns - rocky
Earth - rocky
Mars - rocky
Jupiter - gaseous
Saturn - gaseous
Uranus - gaseous
Neptune - gaseous


Prompt: I'm asking for my wife, who is 46 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 62. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — age 46 is outside the eligible range of 50-80. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 62−10=52, with colonoscopy every 5 years rather than every 10 years. At 46 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 51, I have a 19 pack-year smoking history and quit 5 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 43. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Give me a list of the best bravo tv shows

Response: Real housewives of Beverly Hills, vanderpump rules, southern charm, real housewives of Orange County, real housewives of New York, summer house, winter house


Prompt: I'm asking for my partner, who is 32 and I've had difficulty swallowing (dysphagia) for 5 weeks. Is this something to worry about?

Response:
Yes — get this evaluated. Difficulty swallowing (dysphagia) lasting more than 3 weeks is a recognised red-flag duration, and you're at 5 weeks. Progressive difficulty swallowing warrants prompt evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my wife, who is 48 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 48 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Who were the major players in the Watergate conspiracy?

The Watergate scandal was a major political scandal in the United States involving the administration of President Richard Nixon from 1972 to 1974 that led to Nixon's resignation. The scandal stemmed from the Nixon administration's persistent attempts to cover up its involvement in the June 17, 1972 break-in of the Democratic National Committee headquarters at the Washington, D.C., Watergate Office Building.

Response:
The list begins with the President of the United States, Richard Nixon. John Dean served as the Counsel to the President, and was a lead witness whose testimony blew the case wide open, naming many top presidential aides as being closely involved. H.R. Haldeman, John Ehrlichman, and John Mitchell were all senior members of the administration who resigned in disgraced and were convicted. Howard Hunt and G. Gordon Liddy played major roles in the Watergate break-in.

A major figure in the conspiracy was Daniel Ellsberg, but not for any wrongdoing. Rather, he was a target of the Nixon White House, and an attempted burglary of his psychiatrist's office was just one of the illegal acts that the White House covered up.


Prompt: I'm 39 years old with a mole that has changed. Based on this, is it cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a mole that has changed is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Tell me some point by point details about Art Deco using given text as a reference

Art Deco, short for the French Arts Décoratifs, and sometimes just called Deco, is a style of visual arts, architecture, and product design, that first appeared in France in the 1910s (just before World War I), and flourished in the United States and Europe during the 1920s and 1930s. Through styling and design of the exterior and interior of anything from large structures to small objects, including how people look (clothing, fashion and jewelry), Art Deco has influenced bridges, buildings (from skyscrapers to cinemas), ships, ocean liners, trains, cars, trucks, buses, furniture, and everyday objects like radios and vacuum cleaners.

Response:
1.	A style of visual arts, architecture, and product design, Art Deco—short for the French Arts Décoratifs—first debuted in France in the 1910s, soon before World War I, and flourished in the United States and Europe in the 1920s and 1930s.
2.	Art Deco has influenced bridges, buildings (from skyscrapers to cinemas), ships, ocean liners, trains, cars, trucks, buses, furniture, and common household items like radios and vacuum cleaners.
3.	Art Deco has also influenced styling and design of the exterior and interior of anything from large structures to small objects, as well as how people look (clothing, fashion, and jewellery).