Prompt: Describe the sensation of taking a cold shower and explain the rationale for why someone might take one.

Response:
When you take a shower with very cold water, you throw your body into a temporary state of shock. You feel your skin raise. Your toes may curl a bit. Your eyes may widen. If it is early morning and you're still waking up, you may find that you suddenly feel very alert.

By leaving a room with a warm and comfortable temperature and entering a space with water produced at a chilly and uncomfortable temperature you actually trick your body. The sudden shift produces alertness that can be beneficial for people who are trying to wake up without caffeine and other stimulants or are otherwise trying to train their bodies to tolerate harsh conditions.


Prompt: why did Syd Barrett left the Pink Floyd?

Response: Syd Barrett was one of the main members of the Pink Floyd. He has used drugs a lot and after a while he was not able to perform with the team. Even though the band gave him multiple chances, he could not keep up with the band. In the end, they had to ask him to leave the band. The main reason that he has left the team is his health problems and addiction to drugs.


Prompt:
Extract the names of the cities and rank them in alphabetical order?

The United Kingdom is a constitutional monarchy and parliamentary democracy. Its capital and largest city is London, the capital of England, a global city and financial centre with a population of over 14 million people. Edinburgh, Cardiff and Belfast are the national capitals of Scotland, Wales and Northern Ireland respectively.

Response: The cities listed in alphabetical order are Belfast, Cardiff, Edinburgh and London.


Prompt: What's the current USPSTF recommendation for colorectal cancer screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 37 and I have confirmed Lynch syndrome. How often do I need a colonoscopy?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 37, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 47 and I've had a sore that does not heal for 8 weeks. Do I need to see a doctor about this?

Response:
Yes — get this evaluated. A sore that does not heal lasting more than 3 weeks is a recognised red-flag duration, and you're at 8 weeks. A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my dad, who is 53. Is there a test I should get for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: hey do I need a colonoscopy??

Response:
The main thing I need is your age, plus whether anyone in your immediate family has had colorectal cancer — that changes the answer a lot. For someone at average risk, screening starts at 45. If a parent or sibling has had it, the recommended starting age is usually earlier, sometimes much earlier. What's your age, and is there a family history?

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 38 and I've noticed postmenopausal vaginal bleeding — I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

Postmenopausal vaginal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Is skiing or snowboarding easier?

Response: The answer to this question depends on the individual. Some people find skiing easier, while others find snowboarding easier. Generally, most people have an easier time picking up skiing because the stance on skis is straightforward, similar to walking. On a snowboard, people must stand sideways (like how you'd stand on a skateboard or surfboard). This sideways stance can be more challenging for people to adjust to, and many people report falling on their wrists a lot while learning. Once a person has learned to competently ski or snowboard, it is a matter of personal preference as to what they like to do best.


Prompt: Quick question: I'm 60, I have a 18 pack-year smoking history and quit 15 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Identify which instrument is string or percussion: Sabar, Sharud

Response: Sharud is string, Sabar is percussion.


Prompt: I'm a 48-year-old, I have a 19 pack-year smoking history and quit 5 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 19 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
From the passage provided, extract the date when the 34th Wisconsin Infantry Regiment was organized.

The 34th Wisconsin Infantry Regiment was a conscripted infantry regiment that served in the Union Army during the American Civil War. The 34th Wisconsin Infantry was composed of men drafted by state authorities under General Order No. 94. The regiment was organized at Madison, Wisconsin, and mustered into Federal service December 31, 1862.

Response: The 34th Wisconsin Infantry Regiment was organized on December 31, 1862.


Prompt: My wife just turned 76 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
At 76, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 50 years old, I have a 12 pack-year smoking history and quit 17 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 48-year-old, I smoke and have about a 25 pack-year history. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Based on the text below, please summarise in a few lines

Cricket is a bat-and-ball game played between two teams of eleven players on a field at the centre of which is a 22-yard (20-metre) pitch with a wicket at each end, each comprising two bails balanced on three stumps. The batting side scores runs by striking the ball bowled at one of the wickets with the bat and then running between the wickets, while the bowling and fielding side tries to prevent this (by preventing the ball from leaving the field, and getting the ball to either wicket) and dismiss each batter (so they are "out"). Means of dismissal include being bowled, when the ball hits the stumps and dislodges the bails, and by the fielding side either catching the ball after it is hit by the bat, but before it hits the ground, or hitting a wicket with the ball before a batter can cross the crease in front of the wicket. When ten batters have been dismissed, the innings ends and the teams swap roles. The game is adjudicated by two umpires, aided by a third umpire and match referee in international matches. They communicate with two off-field scorers who record the match's statistical information.

Forms of cricket range from Twenty20, with each team batting for a single innings of 20 overs (each "over" being a set of 6 fair opportunities for the batting team to score) and the game generally lasting three hours, to Test matches played over five days. Traditionally cricketers play in all-white kit, but in limited overs cricket they wear club or team colours. In addition to the basic kit, some players wear protective gear to prevent injury caused by the ball, which is a hard, solid spheroid made of compressed leather with a slightly raised sewn seam enclosing a cork core layered with tightly wound string.

Response: Cricket is a bat-and-ball game played between two teams with eleven players each. The game is played in a field with a pitch at the center with wickets at either end. There is a batting team and a bowling team. The game is adjudicated by two on-field umpires, a third umpire, and a referee. There are various forms of the game, starting from Twenty20, which generally lasts up to 3 hours to test cricket, played over 5 days.


Prompt:
Please write some key points on Booker prize from the given passage.

The 2022 Booker Prize was a literary award given for the best English novel of the year. It was announced on 17 October 2022, during a ceremony hosted by Sophie Duker at the Roundhouse in London. The longlist was announced on 26 July 2022. The shortlist was announced on 6 September. Leila Mottley, at 20, was the youngest longlisted writer to date, and Alan Garner, at 87, the oldest. The majority of the 13 titles were from independent publishers. The prize was awarded to Shehan Karunatilaka for his novel, The Seven Moons of Maali Almeida, receiving £50,000. He is the second Sri Lankan to win the prize, after Michael Ondaatje

Response:
1. The 2022 Booker Prize was a literary honour presented to the year's top English novel.
2. It was revealed on October 17, 2022, at a ceremony Sophie Duker presided over at London's Roundhouse.
3. On July 26, 2022, the longlist was announced.
4. On September 6th, the shortlist was announced.
5. Alan Garner, aged 87, was the oldest longlisted author to date, and Leila Mottley, at 20 years old, was the youngest.
6. Independent publ ishers produced the majority of the 13 books.
7. Shehan Karunatilaka received the award and £50,000 for his book The Seven Moons of Maali Almeida.
8. After Michael Ondaatje, he is the second Sri Lankan to win the award.


Prompt:
Extract the ingredients in bee pollen from the text.

Bee pollen, also known as bee bread and ambrosia, is a ball or pellet of field-gathered flower pollen packed by worker honeybees, and used as the primary food source for the hive. It consists of simple sugars, protein, minerals and vitamins, fatty acids, and a small percentage of other components. Bee pollen is stored in brood cells, mixed with saliva, and sealed with a drop of honey. Bee pollen is harvested as food for humans and marketed as having various, but yet unproven, health benefits.

Response: Bee pollen consists of simple sugars, protein, minerals, vitamins, fatty acids, and some other components.


Prompt: What is Mario Puzo's most famous book?

Response: The Godfather.  Originally published in 1969, is a novel about a fictional crime family in New York.


Prompt: I'm 51, I have a 12 pack-year smoking history and quit 16 years ago — Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 16 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Given this article on Donkey Kong Country 2, who is the villain of the plot and where does the story take place?

Some time after Donkey Kong Country, Donkey Kong is relaxing on the beach, until he is ambushed by the Kremlings. He gets kidnapped and brought to Kaptain K. Rool, King K. Rool's moniker in this game, who then demands the Banana Hoard he unsuccessfully tried to steal in the previous game for a ransom from the Kongs. Instead of complying, Diddy Kong and his friend Dixie resolve to go to the Kremling's home island, Crocodile Isle, to rescue Donkey Kong. Together, they travel through Crocodile Isle and are helped on their way by an assortment of animals to defeat Kaptain K. Rool. Diddy and Dixie eventually battle and defeat K. Rool, releasing Donkey Kong in the process. K. Rool manages to escape though, and shortly after, Diddy and Dixie confront him in the Lost World, a secret area powered by a geyser at the heart of Crocodile Isle. They once again defeat K. Rool, who is hurled into the geyser, causing it to clog up and explode. The explosion causes all of Crocodile Isle to sink, as the Kongs watch K. Rool escape on a small sailboat.

Response: Kaptain K. Rool is the villain and kidnaps Donkey Kong. The story takes places on the Kremling's home island, Crocodile Isle.


Prompt: I just turned 51. How do I check for ovarian cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 50-year-old with a cough that won't go away. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a cough that won't go away is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 35 years old and I recently tested positive for a pathogenic BRCA1 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 35, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My sister is 25 and I've had persistent hoarseness for 5 weeks. Should I get this checked?

Response:
Yes — get this evaluated. Persistent hoarseness lasting more than 3 weeks is a recognised red-flag duration, and you're at 5 weeks. Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my uncle, who is 80, I have a 18 pack-year smoking history and quit 15 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My sister just turned 46. What's the screening test for thyroid cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 52 years old with no family history of breast cancer. Am I due for a mammogram?

Response:
Yes — at 52 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 46 and I've had persistent cough for 6 weeks. Should I get this checked?

Response:
Yes — get this evaluated. Persistent cough lasting more than 3 weeks is a recognised red-flag duration, and you're at 6 weeks. A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 81 years old, I have a 30 pack-year smoking history and quit 20 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My sister just turned 44 with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 44, you are 1 year away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Classify the following water bodies into oceans, seas, rivers and lakes- aral, pacific, baikal, superior, amazon, colorado, indian, arabian, north, baltic, okhotosk, tahoe, victoria, lena, danube, arctic, mekong

Response:
oceans- pacific, indian, arctic
seas- okhotosk, aral, arabian, north, baltic
rivers- amazon, colorado, lena, danube, mekong
lakes- superior, tahoe, victoria , baikal


Prompt: I just turned 50. How do I check for thyroid cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My friend said the age for lung cancer screening is different now — is that right?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 80 years old, I have a 19 pack-year smoking history and quit 17 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 22 and I recently tested positive for a pathogenic BRCA2 variant — Do I start mammograms at 40 like everyone else?

Response:
No — carrying a pathogenic BRCA2 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 22, you would begin MRI surveillance in 3 years.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 27-year-old. Can I get a scan to check for testicular cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 28 and my mother was diagnosed with colorectal cancer at 57 — When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 57 − 10 = 47 — and since 47 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 47, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 21-year-old and I recently tested positive for a pathogenic BRCA1 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 21, you would begin MRI surveillance in 4 years.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 44 with no family history of breast cancer. Am I due for a mammogram?

Response:
Yes — at 44 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 29-year-old and my sister was diagnosed with colorectal cancer at 42. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 32.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 42 − 10 = 32 — and since 32 is earlier than 40, the 10-years-before rule applies, giving 32.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Give me a list of best Studio Ghibli Films

Response:
1. My Neighbour Totoro
2. Princess Mononoke
3. Howl's Moving Castle
4. Spirited Away
5. Kiki's Delivery Service
6. The tale of Princess Kaguya
7. Grave of the Fireflies
8. The Red Turtle
9. Ocean Waves
10. From Up on Poppy Hill


Prompt: Quick question: I'm 81, I have a 21 pack-year smoking history and quit 15 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 51, I have a 12 pack-year smoking history and quit 15 years ago — Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 25-year-old and my brother was diagnosed with colorectal cancer at 68. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 68 − 10 = 58 — and since 58 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 58, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I read that lung cancer screening starts later than what my doctor told me. What's the current guidance?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 30 with no family history of cancer and no symptoms — Do I need to start colon cancer screening yet?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 30, you are 15 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My partner is 38 with no family history of cancer and no symptoms. Am I old enough for colorectal screening?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 38, you are 7 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 72 years old. What's the screening test for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 69 years old. Can I get a scan to check for ovarian cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What is a verb?

Response: A verb is an action word that describes an activity.  Examples of verbs are the following: swimming, hiking, biking, roller skating, or skydiving.  All of these single and combination word examples are tied to an activity that any living thing can do.  For example, a dog can bike ride with a human when the human is pedaling the bike.  Verb use is not limited to humans or people only but applies to all living things.


Prompt: I'm asking for my brother, who is 74 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 74 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 22. Should I be screened for cervical cancer?

Response:
Yes — at 22 you're in the Grade A screening range. Recommended: cervical cytology (Pap test) alone, every 3 years.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: How many U.S. presidents were born in Virginia.

Response: Eight presidents, including the first four of five, were born in Virginia - which is known as the "Mother of Presidents." They include: George Washington, Thomas Jefferson, James Madison, James Monroe, William Henry Harrison, John Tyler, Zachary Taylor and Woodrow Wilson.


Prompt: I just turned 32 and my brother was diagnosed with colorectal cancer at 65. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 65 − 10 = 55 — and since 55 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 55, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my sister, who is 78 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
At 78, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: do I need a colonoscopy, not sure what the age cutoff is

Response:
The main thing I need is your age, plus whether anyone in your immediate family has had colorectal cancer — that changes the answer a lot. For someone at average risk, screening starts at 45. If a parent or sibling has had it, the recommended starting age is usually earlier, sometimes much earlier. What's your age, and is there a family history?

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 51 years old, I smoke and have about a 40 pack-year history. Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 51 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 48. What's the screening test for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My wife is 33. How do I check for ovarian cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 68 years old and I've had difficulty swallowing (dysphagia) for 8 weeks. Is this something to worry about?

Response:
Yes — get this evaluated. Difficulty swallowing (dysphagia) lasting more than 3 weeks is a recognised red-flag duration, and you're at 8 weeks. Progressive difficulty swallowing warrants prompt evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 37 years old and I've noticed a new breast lump. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

A new breast lump is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Tell me a story in a few sentences about food and how a few short words can make someone hungry

Response: Driving past the Farmer's Market Café on the Al in Suffolk, England, I saw a sign outside that read, in huge letters, Ham Hock Hash. Nothing else. No other food, no opening times, nothing. Just three little words that launched a thousand U-turns.


Prompt: I'm 38 years old and my brother was diagnosed with colorectal cancer at 64. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 64 − 10 = 54 — and since 54 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 54, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 20 and I've noticed unexplained rectal bleeding. I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained rectal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my partner, who is 41 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 41 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 28. Should I get screened for thyroid cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my uncle, who is 72 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 48. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — a 15 pack-year history is below the 20 pack-year threshold. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 72 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 40 with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 40, you are 5 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 54-year-old. Is it time to check my prostate?

Response:
Routine PSA screening isn't recommended at 54 for average-risk men. USPSTF guidance addresses ages 55-69 as an individual decision.

Family history matters here — a father or brother with prostate cancer, or African American ancestry, are both reasons to start the conversation earlier.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Do i need a mammogram? I'm not sure if I need one.

Response:
Two things determine this: your age, and whether you carry a BRCA mutation or have a strong family history of breast or ovarian cancer. At average risk, screening is recommended starting at 40, every 2 years. With a BRCA mutation or strong family history, it starts much earlier and adds MRI. What's your age, and is there a relevant family or genetic history?

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 60 with unexplained weight loss. Do I have cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: unexplained weight loss is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My uncle is 20 and I've noticed unexplained rectal bleeding. Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained rectal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My partner just turned 57. Should I get screened for testicular cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Identify which instrument is string or percussion: Lummi stick, Timple

Response: Timple is string, Lummi stick is percussion.


Prompt: Quick question: I'm 37 and I've noticed a new breast lump. I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

A new breast lump is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: hey do I need a mammogram??

Response:
Two things determine this: your age, and whether you carry a BRCA mutation or have a strong family history of breast or ovarian cancer. At average risk, screening is recommended starting at 40, every 2 years. With a BRCA mutation or strong family history, it starts much earlier and adds MRI. What's your age, and is there a relevant family or genetic history?

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my wife, who is 70 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 70 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 49, I have a 21 pack-year smoking history and quit 14 years ago — Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: How do I optimize my Kafka consumption in Spark for low latency?

Response: You can tune the batch size and processing time to ensure that your Spark job can keep up with the data volume and maintain low latency.


Prompt: I just turned 85 with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
At 85, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 48 years old with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 48 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 38 with no family history of breast cancer — Am I due for a mammogram?

Response:
Not yet under current guidance — routine mammography starts at age 40 for average-risk women, so you're 2 years away.

Worth knowing: this changed recently. the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40. Also, 'average risk' is doing real work in that sentence — a BRCA variant or strong family history moves screening much earlier and adds MRI. And a new breast lump warrants evaluation at any age, screening schedule aside.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 81, I have a 18 pack-year smoking history and quit 5 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 18 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My partner is 59 with a parent diagnosed with colorectal cancer at 58. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 58−10=48, with colonoscopy every 5 years rather than every 10 years. At 59 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my mother, who is 57 with a 30 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 62. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 62−10=52, with colonoscopy every 5 years rather than every 10 years. At 57 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: am I due for a pap smear, not sure what the age cutoff is

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 27 and I recently tested positive for a pathogenic BRCA1 variant. When should I start breast cancer screening?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 27, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Do i need a colonoscopy? I'm not sure if I need one.

Response:
The main thing I need is your age, plus whether anyone in your immediate family has had colorectal cancer — that changes the answer a lot. For someone at average risk, screening starts at 45. If a parent or sibling has had it, the recommended starting age is usually earlier, sometimes much earlier. What's your age, and is there a family history?

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Classify the below characters based on whether they are created by Marvel comics or D.C. comics
 Spider-Man, Iron Man, Captain America, Thor, Doctor Strange, Superman, Batman, Wonder Woman, Flash, Aquaman

Response:
DC- Superman, Batman, Wonder Woman, Flash, Aquaman
Marvel- Spider-Man, Iron Man, Captain America, Thor, Doctor Strange


Prompt:
Given a reference text about David Moses ben Meir Dyte, tell me what he is known for.

David Moses ben Meir Dyte (c. 1770–1830) was an English Jewish quill merchant who distinguished himself by preventing the assassination attempt on George III by James Hadfield on 15 May 1800.

Dyte was attending Colley Cibber's play She Would and She Would Not at the Theatre Royal, Drury Lane when Hadfield fired a horsepistol at the King. Dyte, seated directly behind the shooter, struck the assailant and deflected the shot. It is said that Dyte asked as his sole reward the right to sell opera tickets, then a monopoly at the royal disposal. In 1802 he was appointed 'Purveyor of Pens and Quills to the Royal Household'. The incident was immortalised in the play Jew Dyte by Harold Rubinstein.

Dyte was the father of Henry Dyte, who served as Honorary Secretary to the Blind Society; and the grandfather of D. H. Dyte, Surgeon to the Jewish Board of Guardians, and Charles Dyte, a parliamentarian in the colony of Victoria.

Response: David Moses ben Meir Dyte is known for preventing an assassination attempt by James Hadfield on George III.


Prompt: I'm 34 years old and my parent had colon cancer diagnosed at 52. When do I need my first colonoscopy?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 70-year-old with a 35 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 52. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 52−10=42, with colonoscopy every 5 years rather than every 10 years. At 70 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My partner just turned 38 with no family history of breast cancer. Should I be getting mammograms?

Response:
Not yet under current guidance — routine mammography starts at age 40 for average-risk women, so you're 2 years away.

Worth knowing: this changed recently. the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40. Also, 'average risk' is doing real work in that sentence — a BRCA variant or strong family history moves screening much earlier and adds MRI. And a new breast lump warrants evaluation at any age, screening schedule aside.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Identify which animal species is alive or extinct: Pliosaur, Marine Iguana

Response: Pliosaur is extinct, Marine Iguana is alive.


Prompt: Provide a list of ways musicians can earn income from their music craft.

Response:
Paid live music performances

Earning music royalties from your recorded music when it is commercially played, performed or streamed

Getting paid music sync licensing fees for your recorded music to appear in TV, film, or video games

Artist or band merchandise sales

Getting paid to provide voice or instrument lessons to others looking to learn

Paid artist endorsements or sponsorships for other products

Sale of no longer used or needed instruments or music equipment to others who can use them

Writing, recording and delivering a commissioned song for a particular buyer to commemorate a special person or occasion


Prompt: I just turned 43 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 43, you are 2 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 60, I have a 20 pack-year smoking history and quit 15 years ago. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 60 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 15 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 30-year-old and I have confirmed Lynch syndrome (MSH6 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 30, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My father is 51 and I've had persistent cough for 3 weeks. Do I need to see a doctor about this?

Response:
At 3 weeks, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 75 — Should I get a PSA test?

Response:
No — USPSTF gives a Grade D for ages 70 and older: "The USPSTF recommends against PSA-based screening for prostate cancer in men 70 years and older". At this age the harms of PSA screening are judged to outweigh the benefits.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Extract all of the dates mentioned in this paragraph and list them using bullets in the format {Date} - {Description}

The Ghana Space Science and Technology Institute (GSSTI) was first established as a Centre under the School of Nuclear and Allied Sciences (SNAS) in January 2011 and launched in May 2012. It was later upgraded to an Institute in August 2013, to exploit space science and technology for socio-economic development of the country.

Response:
• January 2011 - This is when the Ghana Space Science and Technology Institute (GSSTI) was first established as a Centre under the School of Nuclear and Allied Sciences
• May 2012 - This is when the Ghana Space Science and Technology Institute (GSSTI) was launched
• August 2013 - This is when the Ghana Space Science and Technology Institute was upgraded to an Institute


Prompt: I'm 44 years old with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 44 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 43. Can I get a scan to check for pancreatic cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What's the current USPSTF recommendation for mammography screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (April 30, 2024): screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

What changed: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 47-year-old and I have a mole that's changed in shape over the past couple of months. How do I know if a mole is concerning?

Response:
Yes — any mole that is *changing* should be evaluated, and change in shape is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My uncle is 48, I have a 12 pack-year smoking history and quit 5 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 12 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
What are the primary breathing apparatuses for scuba

Breathing apparatus
Main article: Scuba set

Recreational diver putting on his scuba set before diving
The defining equipment used by a scuba diver is the eponymous scuba, the self-contained underwater breathing apparatus which allows the diver to breathe while diving, and is transported by the diver. It is also commonly referred to as the scuba set.

As one descends, in addition to the normal atmospheric pressure at the surface, the water exerts increasing hydrostatic pressure of approximately 1 bar (14.7 pounds per square inch) for every 10 m (33 feet) of depth. The pressure of the inhaled breath must balance the surrounding or ambient pressure to allow controlled inflation of the lungs. It becomes virtually impossible to breathe air at normal atmospheric pressure through a tube below three feet under the water.

Most recreational scuba diving is done using a half mask which covers the diver's eyes and nose, and a mouthpiece to supply the breathing gas from the demand valve or rebreather. Inhaling from a regulator's mouthpiece becomes second nature very quickly. The other common arrangement is a full face mask which covers the eyes, nose and mouth, and often allows the diver to breathe through the nose. Professional scuba divers are more likely to use full face masks, which protect the diver's airway if the diver loses consciousness.

Open-circuit
Main article: Diving regulator

Aqualung Legend second stage (demand valve) regulator

Aqualung first stage regulator

Gekko dive computer with attached pressure gauge and compass

Suunto submersible pressure gauge display
Open circuit scuba has no provision for using the breathing gas more than once for respiration. The gas inhaled from the scuba equipment is exhaled to the environment, or occasionally into another item of equipment for a special purpose, usually to increase the buoyancy of a lifting device such as a buoyancy compensator, inflatable surface marker buoy or small lifting bag. The breathing gas is generally provided from a high-pressure diving cylinder through a scuba regulator. By always providing the appropriate breathing gas at ambient pressure, demand valve regulators ensure the diver can inhale and exhale naturally and without excessive effort, regardless of depth, as and when needed.

The most commonly used scuba set uses a "single-hose" open circuit 2-stage demand regulator, connected to a single back-mounted high-pressure gas cylinder, with the first stage connected to the cylinder valve and the second stage at the mouthpiece. This arrangement differs from Émile Gagnan's and Jacques Cousteau's original 1942 "twin-hose" design, known as the Aqua-lung, in which the cylinder pressure was reduced to ambient pressure in one or two stages which were all in the housing mounted to the cylinder valve or manifold. The "single-hose" system has significant advantages over the original system for most applications.

In the "single-hose" two-stage design, the first stage regulator reduces the cylinder pressure of up to about 300 bars (4,400 psi) to an intermediate pressure (IP) of about 8 to 10 bars (120 to 150 psi) above ambient pressure. The second stage demand valve regulator, supplied by a low-pressure hose from the first stage, delivers the breathing gas at ambient pressure to the diver's mouth. The exhaled gases are exhausted directly to the environment as waste through a non-return valve on the second stage housing. The first stage typically has at least one outlet port delivering gas at full tank pressure which is connected to the diver's submersible pressure gauge or dive computer, to show how much breathing gas remains in the cylinder.

Rebreather

An Inspiration electronic fully closed circuit rebreather
Main article: Diving rebreather
Less common are closed circuit (CCR) and semi-closed (SCR) rebreathers which, unlike open-circuit sets that vent off all exhaled gases, process all or part of each exhaled breath for re-use by removing the carbon dioxide and replacing the oxygen used by the diver. Rebreathers release few or no gas bubbles into the water, and use much less stored gas volume, for an equivalent depth and time because exhaled oxygen is recovered; this has advantages for research, military, photography, and other applications. Rebreathers are more complex and more expensive than open-circuit scuba, and special training and correct maintenance are required for them to be safely used, due to the larger variety of potential failure modes.

In a closed-circuit rebreather the oxygen partial pressure in the rebreather is controlled, so it can be maintained at a safe continuous maximum, which reduces the inert gas (nitrogen and/or helium) partial pressure in the breathing loop. Minimising the inert gas loading of the diver's tissues for a given dive profile reduces the decompression obligation. This requires continuous monitoring of actual partial pressures with time and for maximum effectiveness requires real-time computer processing by the diver's decompression computer. Decompression can be much reduced compared to fixed ratio gas mixes used in other scuba systems and, as a result, divers can stay down longer or require less time to decompress. A semi-closed circuit rebreather injects a constant mass flow of a fixed breathing gas mixture into the breathing loop, or replaces a specific percentage of the respired volume, so the partial pressure of oxygen at any time during the dive depends on the diver's oxygen consumption and/or breathing rate. Planning decompression requirements requires a more conservative approach for a SCR than for a CCR, but decompression computers with a real-time oxygen partial pressure input can optimise decompression for these systems. Because rebreathers produce very few bubbles, they do not disturb marine life or make a diver's presence known at the surface; this is useful for underwater photography, and for covert work.

Response: The most common breathing apparatus for Scuba Diving is an open circuit single hose 2-stage demand regulator connected to a single gas cylinder.  A less common apparatus is a Closed Circuit or Semi-Closed rebreather.