Prompt: I'm 46 years old and I have a mole that's changed in shape and size over the past couple of months. Should I get it checked?

Response:
Yes — any mole that is *changing* should be evaluated, and change in shape and size is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My husband is 80, I have a 12 pack-year smoking history and quit 17 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 33 years old with no family history of breast cancer. Should I be getting mammograms?

Response:
Not yet under current guidance — routine mammography starts at age 40 for average-risk women, so you're 7 years away.

Worth knowing: this changed recently. the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40. Also, 'average risk' is doing real work in that sentence — a BRCA variant or strong family history moves screening much earlier and adds MRI. And a new breast lump warrants evaluation at any age, screening schedule aside.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Given this text of Mao Zedong, tell me how many people were killed in Mao's era through starvation, persecution, prison labour, and mass executions?

Mao Zedong (26 December 1893 – 9 September 1976), also known as Chairman Mao, was a Chinese communist revolutionary who was the founder of the People's Republic of China (PRC), which he led as the chairman of the Chinese Communist Party from the establishment of the PRC in 1949 until his death in 1976. Ideologically a Marxist–Leninist, his theories, military strategies, and political policies are collectively known as Maoism.

Mao was the son of a prosperous peasant in Shaoshan, Hunan. He supported Chinese nationalism and had an anti-imperialist outlook early in his life, and was particularly influenced by the events of the Xinhai Revolution of 1911 and May Fourth Movement of 1919. He later adopted Marxism–Leninism while working at Peking University as a librarian and became a founding member of the Chinese Communist Party (CCP), leading the Autumn Harvest Uprising in 1927. During the Chinese Civil War between the Kuomintang (KMT) and the CCP, Mao helped to found the Chinese Workers' and Peasants' Red Army, led the Jiangxi Soviet's radical land reform policies, and ultimately became head of the CCP during the Long March. Although the CCP temporarily allied with the KMT under the Second United Front during the Second Sino-Japanese War (1937–1945), China's civil war resumed after Japan's surrender, and Mao's forces defeated the Nationalist government, which withdrew to Taiwan in 1949.

On 1 October 1949, Mao proclaimed the foundation of the PRC, a Marxist–Leninist single-party state controlled by the CCP. In the following years he solidified his control through the Chinese Land Reform against landlords, the Campaign to Suppress Counterrevolutionaries, the "Three-anti and Five-anti Campaigns", and through a truce in the Korean War, which altogether resulted in the deaths of several million Chinese. From 1953 to 1958, Mao played an important role in enforcing command economy in China, constructing the first Constitution of the PRC, launching the industrialisation program, and initiating military projects such as the "Two Bombs, One Satellite" project and Project 523. His foreign policies during this time were dominated by the Sino-Soviet split which drove a wedge between China and the Soviet Union. In 1955, Mao launched the Sufan movement, and in 1957 he launched the Anti-Rightist Campaign, in which at least 550,000 people, mostly intellectuals and dissidents, were persecuted. In 1958, he launched the Great Leap Forward that aimed to rapidly transform China's economy from agrarian to industrial, which led to the deadliest famine in history and the deaths of 15–55 million people between 1958 and 1962. In 1963, Mao launched the Socialist Education Movement, and in 1966 he initiated the Cultural Revolution, a program to remove "counter-revolutionary" elements in Chinese society which lasted 10 years and was marked by violent class struggle, widespread destruction of cultural artifacts, and an unprecedented elevation of Mao's cult of personality. Tens of millions of people were persecuted during the Revolution, while the estimated number of deaths ranges from hundreds of thousands to millions. After years of ill health, Mao suffered a series of heart attacks in 1976 and died at the age of 82. During the Mao era, China's population grew from around 550 million to over 900 million while the government did not strictly enforce its family planning policy.

Widely regarded as one of the most influential figures of the twentieth century, Mao remains a controversial figure within and outside China. Beyond politics, Mao is also known as a theorist, military strategist, and poet. Mao has been credited with transforming China from a semi-colony to a leading world power, with greatly advanced literacy, women's rights, basic healthcare, primary education and life expectancy. However, Mao's government was responsible for vast numbers of deaths, with estimates ranging from 40 to 80 million victims through starvation, persecution, prison labour, and mass executions. During his leadership tenure, China was heavily involved with other Asian communist conflicts such as the Korean War, the Vietnam War, and the Cambodian Civil War.

Response: Mao's government was responsible for vast numbers of deaths, with estimates ranging from 40 to 80 million victims through starvation, persecution, prison labour, and mass executions.


Prompt:
What caused the Global Financial Crises?

The preconditioning for the financial crisis were complex and multi-causal. Almost two decades prior, the U.S. Congress had passed legislation encouraging financing for affordable housing. However, in 1999, parts of the Glass-Steagall legislation, which had been adopted in 1933, were repealed, permitting financial institutions to commingle their commercial (risk-averse) and proprietary trading (risk-taking) operations. Arguably the largest contributor to the conditions necessary for financial collapse was the rapid development in predatory financial products which targeted low-income, low-information homebuyers who largely belonged to racial minorities. This market development went unattended by regulators and thus caught the U.S. government by surprise.

Response: There were multiple factors that caused the financial crises.  Two decades before the crisis, the U.S Government implemented multiple new laws to help encourage financing for affordable housing.  However, in 1999, portions of the Glass-Steagall act, which was passed by congress in 1933, was repealed and as a result, created more overall risk in the financial system as it allowed institutions to commingle low risk real estate investments with riskier investment operations.  The final major factor was a large increase in predatory home loan lending practices which targeted low-income, low-credit, uninformed homebuyers (mostly racial minorities).  The severity of these factors went unnoticed by U.S financial regulators and by the time the effects surfaced, the government was caught by surprise.


Prompt: I'm asking for my partner, who is 22 and I have a mole that's changed in color over the past couple of months. How do I know if a mole is concerning?

Response:
Yes — any mole that is *changing* should be evaluated, and change in color is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Who regulates banks in Australia?

Response: The Australian Prudential Regulatory Authority (APRA) is the prudential regulator of the Australian financial services industry.


Prompt: Would you typically find each of the following items in a bathroom, bedroom, kitchen or living room? Couch, pillow, dish soap, bedside table, oven, shower, toilet, coffee table, coffee machine

Response: Couch: living room, pillow: bedroom, dish soap: kitchen, bedside table: bedroom, oven: kitchen, shower: bathroom, toilet: bathroom, coffee table: living room, coffee machine: kitchen


Prompt: I'm asking for my uncle, who is 54 and I've had persistent cough for 1 week. Do I need to see a doctor about this?

Response:
At 1 week, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 60. Do I need prostate cancer screening?

Response:
This one is genuinely a choice rather than a yes or no. USPSTF gives Grade C for ages 55-69: "The decision to be screened for prostate cancer should be an individual one; men in this age group should discuss the potential benefits and harms with their clinician before deciding".

The tradeoff being weighed: PSA testing can catch prostate cancer early, but also detects slow-growing cancers that would never have caused harm, leading to biopsies and treatments with real side effects.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 65-year-old. How do I check for pancreatic cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 48, I have a 21 pack-year smoking history and quit 17 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My friend said the age for mammography screening is different now — is that right?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (April 30, 2024): screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

What changed: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My aunt just turned 65 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 48. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 65 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: How to lose weight?

Response:
1.	Drink Plenty of water
2.	Take proper sleep
3.	Eat high fibre foods
4.	Avoid junk foods
5.	Eat Regular meals
6.	Eat plenty of fruit and veggies
7.	Exercise thrice a week


Prompt: I'm asking for my mom, who is 64. How do I check for ovarian cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 33 years old with no family history of breast cancer. Am I due for a mammogram?

Response:
Not yet under current guidance — routine mammography starts at age 40 for average-risk women, so you're 7 years away.

Worth knowing: this changed recently. the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40. Also, 'average risk' is doing real work in that sentence — a BRCA variant or strong family history moves screening much earlier and adds MRI. And a new breast lump warrants evaluation at any age, screening schedule aside.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Which onsen villages in Japan are the best to visit for foreign tourists? And what should I do once I'm in an onsen village?

Response: There are many great onsen villages in Japan in which tourists of any nationals can enjoy the experience of bathing in natural hot springs. Some great examples are Hakone, Kusatsu and Nyuto Onsen. Ideally, you would want to spend a day or two in a village as these villages are often located in beautiful nature and offer great opportunities for hiking and walking.


Prompt: I just turned 29. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: hey do I need a mammogram??

Response:
Two things determine this: your age, and whether you carry a BRCA mutation or have a strong family history of breast or ovarian cancer. At average risk, screening is recommended starting at 40, every 2 years. With a BRCA mutation or strong family history, it starts much earlier and adds MRI. What's your age, and is there a relevant family or genetic history?

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: How big is the universe?

Response: While the entire size of the universe is unknown, scientists have estimated that the universe is approximately 93 billion light-years in diameter.


Prompt: I'm a 76-year-old with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
At 76, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 85 with no family history of cancer and no symptoms. Am I due for colorectal cancer screening?

Response:
At 85, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What's the current USPSTF recommendation for mammography screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (April 30, 2024): screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

What changed: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 79-year-old, I have a 40 pack-year smoking history and quit 5 years ago. Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 79 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 5 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: In SQL, how can I filter table rows based on a column condition?

Response: SELECT <columns> FROM <table> WHERE <column> == <condition>


Prompt: I'm a 40-year-old with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 40 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What is Nando's?

Response:
Nando's is a South African/Portuguese inspired chicken restaurant that has a number or restaurants around the UK.
It is piri piri inspired and specialises in grilled chicken.
The piri piri sauce is made from Birds Eye chillis from Mozambique which is basted across the grilled chicken.


Prompt: I'm 30 years old and I have confirmed Lynch syndrome (MSH2 variant). What's my screening schedule?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 30, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 43 and my father was diagnosed with colorectal cancer at 70. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 70 − 10 = 60 — and since 60 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 60, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 82-year-old, I have a 25 pack-year smoking history and quit 10 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 38 with a mole that has changed. Is this definitely nothing? I'd rather not go to the doctor.

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a mole that has changed is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
What's the relation between the Kushan Empire and the Sassanid Empire in Iran?

The Kushan Empire  was a syncretic empire, formed by the Yuezhi, in the Bactrian territories in the early 1st century. It spread to encompass much of modern-day territory of Uzbekistan, Afghanistan, Pakistan and Northern India. The Sasanian or Sassanid Empire officially known as Eranshahr  was the last Iranian empire before the early Muslim conquests of the 7th–8th centuries AD. Named after the House of Sasan, it endured for over four centuries, from 224 to 651 AD, making it the longest-lived Persian imperial dynasty.[

Response: Kushano-Sasanian Kingdom (also called Kushanshahs,  or Koshano Shao in Bactrian, or Indo-Sasanians) is a historiographic term used by modern scholars to refer to a branch of the Sasanian Persians who established their rule in Bactria during the 3rd and 4th centuries CE at the expense of the declining Kushans. They captured the provinces of Sogdiana, Bactria and Gandhara from the Kushans in 225 CE. The Sasanians established governors for the Sasanian Empire, who minted their own coinage and took the title of Kushanshas, i.e. "Kings of the Kushans". They are sometimes considered as forming a "sub-kingdom" inside the Sassanid Empire.


Prompt: I'm 39 and I've had persistent hoarseness for 2 weeks — Do I need to see a doctor about this?

Response:
At 2 weeks, this is below the 3-week threshold usually used to define persistent hoarseness as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 58. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My wife is 23 and I've noticed a new breast lump. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

A new breast lump is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Malibamat'so River

The Malibamat'so River is a river in northern Lesotho. Its origin is near to the South African border, where it drains the eastern slopes of the Maloti Range. It flows southwards past the village of Lejone, and eventually joins the Senqu River 5 kilometres (3.1 mi) northeast of Mohlanapeng.

The Malibamat'so forms the northern arm of the Katse Dam reservoir, a part of the Lesotho Highlands Water Project. Katse is Africa's highest elevation dam at 1,993 metres (6,539 ft) above sea level. Here the river is joined by the Bokong/Bokung River. Downstream the Malibamat'so's left bank tributaries are the Matsoku and Semenanyane Rivers, before it forms a right bank tributary of the Senqu/Orange River.

Response:
Malibamat'so River is a river in northern Lesotho. Its origin is near to the South African border, where it drains the eastern slopes of the Maloti Range. It flows southwards past the village of Lejone, and eventually joins the Senqu River 5 kilometres (3.1 mi) northeast of Mohlanapeng.

The Malibamat'so forms the northern arm of the Katse Dam reservoir, a part of the Lesotho Highlands Water Project. Katse is Africa's highest elevation dam at 1,993 metres (6,539 ft) above sea level. Here the river is joined by the Bokong/Bokung River.


Prompt: I'm asking for my mother, who is 60. Is there a test I should get for ovarian cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 62 and I've had difficulty swallowing (dysphagia) for 2 weeks. Do I need to see a doctor about this?

Response:
At 2 weeks, this is below the 3-week threshold usually used to define difficulty swallowing (dysphagia) as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Progressive difficulty swallowing warrants prompt evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Is it a good idea to have a protein shake after a gym workout? How do I make one?

Response:
Most health professionals agree that consuming extra protein with strength training is helpful. Some experts recommend one gram of protein per pound of body weight over the entire day, though there are a variety of studies on the subject with differing recommendations. The recent consensus view is a post-workout recovery meal is a good idea, typically within 30 minutes to two hours of completing strength training. A mix of carbohydrates and protein is recommended.

To make one for yourself:
1. Get a good protein source, typically a protein powder. Casein and Whey proteins are popular choices.
2. Add the protein powder to a shaker. Some are small and handheld; other models use electricity.
3. Following the instructions on the protein powder, add water or milk. Typically, 4 to 8 oz of liquid for one scoop (30g) of powder.
4. Optionally add your favorite fruits, such as bananas or strawberries.
5. Shake things together for around a minute.

Enjoy, but be sure to vary your protein sources as a part of a healthy and balanced diet!


Prompt:
Based on this paragraph, how many younger siblings did Kennedy have?

Kennedy was born on February 22, 1932, at St. Margaret's Hospital in the Dorchester section of Boston, Massachusetts. He was the youngest of the nine children of Joseph Patrick Kennedy and Rose Fitzgerald, members of prominent Irish American families in Boston. They constituted one of the wealthiest families in the nation after their marriage. His eight siblings were Joseph Jr., John, Rosemary, Kathleen, Eunice, Patricia, Robert, and Jean. His older brother John asked to be the newborn's godfather, a request his parents honored, though they did not agree to his request to name the baby George Washington Kennedy (Ted was born on President George Washington's 200th birthday). They named the boy after their father's assistant.

Response: Based on this paragraph, Kennedy had no younger siblings, as he was the youngest of nine children.


Prompt: I'm 29 years old and I have confirmed Lynch syndrome (MLH1 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 29, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 55 with a breast lump. Based on this, is it cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a breast lump is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Who prepares the Global Hunger Index?

Response: Global Hunger Index is jointly prepared by Welhunger Life and Concern Worldwide


Prompt: Write the first paragraph of a blog post describing the appeal of Boston as a tourist destination

Response: Boston is a vibrant city with a rich history, incredible architecture, and diverse culture. Its cobblestone streets, charming neighborhoods, and vibrant nightlife make it an ideal destination for visitors. From the Freedom Trail to the Boston Common, Boston offers visitors a unique experience unlike any other. From historic sites to vibrant nightlife, Boston is a great place to visit and explore. The suburbs are great too.


Prompt: I'm 20 and I've had persistent hoarseness for 3 weeks — Should I get this checked?

Response:
At 3 weeks, this is below the 3-week threshold usually used to define persistent hoarseness as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My aunt is 38 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 38, you are 7 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 60, I smoke and have about a 20 pack-year history — Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 60 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my aunt, who is 35. Should I be screened for cervical cancer?

Response:
Yes — at 35 you're in the Grade A screening range. Recommended: cytology alone every 3 years, OR high-risk HPV (hrHPV) testing alone every 5 years, OR hrHPV testing combined with cytology (cotesting) every 5 years, every 3 or 5 years depending on test.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 39 years old with no family history of breast cancer. Should I be getting mammograms?

Response:
Not yet under current guidance — routine mammography starts at age 40 for average-risk women, so you're 1 year away.

Worth knowing: this changed recently. the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40. Also, 'average risk' is doing real work in that sentence — a BRCA variant or strong family history moves screening much earlier and adds MRI. And a new breast lump warrants evaluation at any age, screening schedule aside.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Write an email to someone updating that I’ve accepted the position at their company to which they referred me

Response:
Hi,

I wanted to update you that I accepted the offer!

Thank you for being such a huge part of this, from coffee chats to interview prepping. You made all the difference in my application journey and I’m so excited to work with you.


Prompt: I'm asking for my sister, who is 81, I have a 19 pack-year smoking history and quit 5 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 19 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My mother is 50, I have a 21 pack-year smoking history and quit 14 years ago. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 21 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 81, I have a 20 pack-year smoking history and quit 14 years ago — Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 81 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Where does Kieran Liam McAnespie come from?

Kieran Liam McAnespie (born 11 September 1979) is a football manager and former player. Capable of playing as a full-back or winger, he appeared in the Scottish Premier League for St Johnstone and Hearts. Born in England, he represented the Scotland U21 national team internationally

Response: Kieran Liam McAnespie was born in England.


Prompt: What are some popular movies from the 1980s?

Response: Some popular movies that were released in the 1980s are Sixteen Candles, The Breakfast Club, Pretty in Pink, Scarface, The Outsiders, Heathers, Stand By Me, ET, The Princess Bride, The Terminator, Aliens, Friday the 13th, St. Elmo's Fire, Children of the Corn, Grease 2, Purple Rain, Clue, A Nightmare on Elm Street, Lucas, Gremlins, Better Off Dead and Some Kind of Wonderful


Prompt: I'm a 37-year-old and I've noticed a new breast lump. Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

A new breast lump is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Given this paragraph about Pittsford, New York, what year was the town settled?

The Town of Pittsford (formerly part of the town of Northfield) was settled in 1789 and incorporated in 1796. The Village of Pittsford was incorporated in 1827. It was named by Colonel Caleb Hopkins, War of 1812 hero and subsequently Pittsford Town Supervisor, for the town of his birth, Pittsford, Vermont.

Response: The town of Pittsford was settled in 1789.


Prompt: Name some books that Jane Austen is best known for.

Response: Jane Austen’s novels were not popular during her lifetime. Today, her most popular novels are ‘Pride and Prejudice’ (1813) and ‘Sense and Sensibility’ (1811). ‘Pride and Prejudice’ follows the relationship between Elizabeth Bennet, a country woman who makes hasty judgements, and Fitzwilliam Darcy, a proud aristocrat, as they overcome their differences and fall in love. ‘Sense and Sensibility’ follows the three Dashwood sisters who are uprooted from their home and must strike a balance between pragmatism and romance to find love and happiness.


Prompt: Quick question: I'm 57 with fatigue for weeks. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: fatigue for weeks is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 41-year-old and I have confirmed Lynch syndrome (MSH6 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 41, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my wife, who is 49, I have a 21 pack-year smoking history and quit 16 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 16 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 22 — How do I check for ovarian cancer early?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for ovarian cancer in asymptomatic women."

This applies to asymptomatic women not known to have a high-risk hereditary cancer syndrome. The reasoning: available screening methods (transvaginal ultrasound and CA-125 testing) do not reduce ovarian cancer mortality and produce substantial harms through false-positive results leading to unnecessary surgery.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for ovarian cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Ovarian Cancer: Screening, February 2018 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 49, I have a 12 pack-year smoking history and quit 16 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 12 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my sister, who is 68 and I've had persistent hoarseness for 4 weeks. Should I get this checked?

Response:
Yes — get this evaluated. Persistent hoarseness lasting more than 3 weeks is a recognised red-flag duration, and you're at 4 weeks. Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 88-year-old with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Routine screening is generally not recommended past age 85. USPSTF guidance covers adults up to 85; beyond that, the decision depends on overall health and life expectancy and should be made with a clinician.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 65-year-old, I have a 18 pack-year smoking history and quit 20 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 18 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 20 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What are the starting Pokemon in Pokemon Red and Blue?

Response: The grass type Pokemon Bulbasaur, the water type Pokemon Squirtle, and the fire type Pokemon Charmander.


Prompt: My aunt just turned 46 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 46 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
What is gardening?

Gardening is the practice of growing and cultivating plants as part of horticulture. In gardens, ornamental plants are often grown for their flowers, foliage, or overall appearance; useful plants, such as root vegetables, leaf vegetables, fruits, and herbs, are grown for consumption, for use as dyes, or for medicinal or cosmetic use.

Gardening ranges in scale from fruit orchards, to long boulevard plantings with one or more different types of shrubs, trees, and herbaceous plants, to residential back gardens including lawns and foundation plantings, all the way to container gardens grown inside or outside. Gardening may be very specialized, with only one type of plant grown, or involve a variety of plants in mixed plantings. It involves an active participation in the growing of plants, and tends to be labor-intensive, which differentiates it from farming or forestry.

Response: Gardening is laying out and caring for a plot of ground devoted partially or wholly to growing plants such as flowers, herbs, or vegetables.


Prompt: What is an actuary?

Response: An actuary is a specialist in the valuation of the financial impact of risk and uncertainty. They apply statistical techniques and expert industry knowledge. Actuaries usually work in the insurance and banking industries.


Prompt: I'm 37 years old with a cough that won't go away. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a cough that won't go away is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: what happens when you blow air into alkaline water?

Response: When you blow air into alkaline water the C02 from your breath creates carbonic acid which lowers the potential hydrogen of the alkaline water.  If you blow air into the alkaline water long enough the alkaline water will eventually turn acidic.  Potential hydrogen drops can be used to measure the PH to show the effect of blowing air into alkaline water.  PH drops will show alkaline water as blue and purple, and they will show acidic water as yellow.


Prompt:
What is wine?

Wine is an alcoholic drink typically made from fermented grapes. Yeast consumes the sugar in the grapes and converts it to ethanol and carbon dioxide, releasing heat in the process. Different varieties of grapes and strains of yeasts are major factors in different styles of wine. These differences result from the complex interactions between the biochemical development of the grape, the reactions involved in fermentation, the grape's growing environment (terroir), and the wine production process. Many countries enact legal appellations intended to define styles and qualities of wine. These typically restrict the geographical origin and permitted varieties of grapes, as well as other aspects of wine production. Wines can be made by fermentation of other fruit crops such as plum, cherry, pomegranate, blueberry, currant and elderberry.

Response: Wine is an alcoholic drink typically made from fermented grapes.


Prompt: What are some of the sight seeing and outdoor activities to do in Portugal, Spain

Response:
Day 1: Arrival in Lisbon
- Transfer from the airport to the hotel (8.6 miles/14 km)

Day 2: Lisbon
- Visit to Belém Tower (5.5 miles/9 km)
- Jerónimos Monastery
- St. George's Castle
- Alfama neighborhood

Day 3: Sintra
- Visit to Pena Palace (18.7 miles/30 km)
- Sintra National Palace
- Cabo da Roca (14.6 miles/23.5 km)

Day 4: Cascais
- Beach day in Cascais (16.8 miles/27 km)
- Visit to Boca do Inferno
- Cascais Marina

Day 5: Óbidos
- Visit to Óbidos Castle (52.8 miles/85 km)
- Walk through the village
- Visit to Alcobaça Monastery (22.8 miles/37 km)

Day 6: Nazaré
- Visit to Nazaré beach (30.7 miles/49.5 km)
- Cable car ride
- Visit to the Chapel of Our Lady of Nazaré

Day 7: Coimbra
- Visit to Coimbra University (68.3 miles/110 km)
- Walk through the historic center
- Visit to the Old Cathedral

Day 8: Aveiro
- Boat ride through the canals of Aveiro (44.7 miles/72 km)
- Visit to the Aveiro Cathedral
- Walk through the Fisherman's Quarter

Day 9: Porto
- Visit to the Ribeira neighborhood (46.6 miles/75 km)
- Climb the Clérigos Tower
- Visit to the São Bento train station
- Tour of the Port wine cellars

Day 10: Departure from Porto
- Transfer from the hotel to the airport (10.4 miles/17 km)


Prompt:
Based on this article, considerations of what time zone is used for determining what land is in the dead man zone?

The dead man zone is the area directly around a bushfire that is likely to burn within five minutes given the current wind conditions or an anticipated change in wind direction. The distance this zone extends from the firefront is highly dependent on terrain, windspeed, fuel type and composition, relative humidity and ambient temperature, and can range from under 100 metres (330 ft) to well over 1 kilometre (3,300 ft).

Response: A five minute period in the future is used for creating the dead man zone.


Prompt: My brother just turned 25 with a cough that won't go away. Based on this, is it cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a cough that won't go away is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Give me a bullet list of some popular dashboard and visualisation tools

Response:
- Microsoft Power BI. It integrates very well with Microsoft office ecosystem and simple to use and get started
- Tableau. Although having the same value proposition as that of Power BI, analysts generally prefer it when they need to create powerful and complex dashboards. Like Power Bi, it also supports tons of data connectors.
- Metabase. It is an open-source BI and data visualization tool which is good for getting your team started with a baseline dashboard layer.
- Datapad. This tool recently started to gain popularity for KPI dashboards. Thanks to its mobile-first KPI dashboard, it is ideal for small to medium enterprises and a lot of solopreneurs uses it to manage their business KPIs.


Prompt: Quick question: I'm 51, I smoke and have about a 19 pack-year history. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 19 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
What is Ana María Gonzalez famous for

Ana María González (born 13 April 1951) is a Spanish lyric soprano trained in Argentina, known for performing at the Teatro Colón from 1973 to 1994. Although associated with the Italian lyric repertoire, she also excelled in lyric soprano roles of the French repertoire such as Manon, Marguerite, and Juliette, which brought her international fame.

Response: Ana María Gonzalez (born 13 April 1951) is a Spanish lyric soprano trained in Argentina, known for performing at the Teatro Colón from 1973 to 1994. Although associated with the Italian lyric repertoire, she also excelled in lyric soprano roles of the French repertoire such as Manon, Marguerite, and Juliette, which brought her international fame.


Prompt: I'm asking for my mom, who is 51, I have a 12 pack-year smoking history and quit 10 years ago. Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: should I get checked for lung cancer?

Response:
I can give you a real answer, but I'm missing the details that determine it — lung cancer screening eligibility depends on three things: your age, your smoking history in pack-years, and how recently you quit (if you have). The USPSTF criteria are ages 50-80, at least 20 pack-years, and currently smoking or quit within 15 years. Tell me those three things and I can give you a direct yes or no.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My father just turned 45 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 45 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Tell me whether these are literary characters or fruits: Gandalf, banana, Frodo Baggins, Aragorn, orange, apple, Sauron

Response:
Gandalf - literary character
Banana - fruit
Frodo Baggins - literary character
Aragorn  - literary character
orange - fruit
apple - fruit
Sauron - literary character


Prompt: How can I contribute to Spark?

Response: Yes, Spark is an open source project and anyone can contribute to it.


Prompt: I just turned 20. Do I need a Pap smear?

Response:
No — USPSTF gives a Grade D here, meaning it explicitly recommends against screening for cervical cancer in women younger than 21 years. Screening starts at 21.

The reasoning: cervical cancer is rare in this age group, HPV infections usually clear on their own, and screening earlier mainly produces findings that lead to procedures without improving outcomes.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 22. Can I get a scan to check for thyroid cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What does airplane glide ratio mean?

Response: Airplane glide ratio is a measure of an airplane's glide performance. It is the ratio between distance forward to distance downward for an airplane in free, unpowered flight. Glide ratio is affected by properties such as aerodynamical drag, wing construction, and more. Sailplanes are among the most efficient airplanes, achieving glide ratios over 70:1.


Prompt:
Given this paragraph about Africa, why Africa's per capita  GDP is low?

Africa is the world's second-largest and second-most populous continent, after Asia in both aspects. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 20% of Earth's land area and 6% of its total surface area. With 1.4 billion people as of 2021, it accounts for about 18% of the world's human population. Africa's population is the youngest amongst all the continents; the median age in 2012 was 19.7, when the worldwide median age was 30.4. Despite a wide range of natural resources, Africa is the least wealthy continent per capita and second-least wealthy by total wealth, behind Oceania. Scholars have attributed this to different factors including geography, climate, tribalism, colonialism, the Cold War, neocolonialism, lack of democracy, and corruption. Despite this low concentration of wealth, recent economic expansion and the large and young population make Africa an important economic market in the broader global context.

Response: While there are several reasons high population growth, corruption and colonialism and neocolonialism are some of the the factors.


Prompt: I just turned 60, I have a 21 pack-year smoking history and quit 17 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 17 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 50, I have a 20 pack-year smoking history and quit 10 years ago. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 10 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What are AirPods?

Response: Air Pods are an in ear headphone product made and sold by Apple. Their unique market differentiators are a software simulated spatial audio system and noise canceling features.


Prompt: What types of sport fish do most anglers target in New England?

Response: There are many types of game fish that anglers target in New England. Fresh water anglers generally fish for large mouth bass, small mouth bass and various types of trout.  Children often learn to fish by catching sunfish.  Fishing in the ocean in New England offers many additional options to target including Striped Bass, Black Sea Bass, Bluefish, as well as much larger game fish like Bluefin Tuna, Albacore, False Albacore, Bonito, and many species of shark. Each season produces different fish, be sure to check with your local fish and game authority to ensure you have the proper license and which species are able to be targeted.


Prompt: Quick question: I'm 65, I have a 40 pack-year smoking history and quit 10 years ago. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 65 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 10 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 49 with blood in the stool. Based on this, is it cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: blood in the stool is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my dad, who is 35 and my father was diagnosed with colorectal cancer at 62. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 62 − 10 = 52 — and since 52 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 52, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 20 and I recently tested positive for a pathogenic BRCA1 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 20, you would begin MRI surveillance in 5 years.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 27-year-old and I've noticed blood in the urine (haematuria). Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Blood in the urine (haematuria) is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 78, I have a 30 pack-year smoking history and quit 17 years ago — Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 17 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Based on the reference text, what was the start date and the expected completion date of the reconstruction project on the Howard Frankland bridge.

After the widening project in 1992, Interstate 275 was increased to eight lanes on the bridge itself. However, this did not increase capacity on either end of the bridge. Backups were still seen on the Howard Frankland heading into Tampa, primarily due to a bottleneck at the SR 60/Veterans Expressway exit. On the St. Petersburg side, after a comprehensive reconstruction project that took over ten years, lane counts were increased from four lanes prior to the bridge to six lanes through downtown St. Petersburg, and eight lanes from Gandy Boulevard to the bridge.

A reconstruction project was planned to begin in 2017 for the new Gateway Expressway project, a plan to build a new toll road to connect different parts in Pinellas County. However, FDOT planned to reconstruct the interstate in smaller phases rather than the original larger two-phase project and the start of construction was delayed to 2020.

Once the reconstruction project is finished in 2025, major traffic congestion on the Howard Frankland bridge is expected to be significantly reduced by the addition of new lanes. On January 7, 2021, FDOT postponed by a week to January 16, 2021 the start date for removing an overpass and the corresponding exit ramp over I-275. It had been scheduled to shut down by 8 p.m., EST, January 9, through January 10. This work was part of the U.S. $600 million toll road project. On January 16 to 17, 2021, workers removed the 4th street north interchange bridge (overpass) from 8 p.m. on January 16, to 12 p.m. on January 17. Exit 32 was closed until late 2021 while the new overpass is constructed.

Overall construction on this large project began in fall 2020 and completion is expected in late 2025. A completely new bridge will carry southbound traffic. Once that bridge is completed, the existing southbound bridge will be converted to carry northbound traffic. When all traffic is moved to the final alignment, the existing northbound bridge will be removed. The newly built bridge for southbound traffic will include a separate pathway for pedestrian and bicycle traffic, and additional vehicle traffic lanes.[

Response: The reconstruction project of the Howard Frankland bridge started in fall of 2020 and is expected to be completed in 2025.


Prompt: What is appealing about Charleston in South Carolina?

Response: Charleston has a lot of historical sites that you can visit, which is great for educational purposes. The food is very diverse and provides many options for the pickiest of eaters. The low country is a beautiful scenery that sets the scene for cocktails, sunset catching and listening to the sounds of the creatures. There is a lot to see and learn from Charleston because of its southern charm and the people that have built its culture into a blossoming city.


Prompt: I'm a 49-year-old, I have a 20 pack-year smoking history and quit 10 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 80 with no family history of breast cancer — Do I need breast cancer screening yet?

Response:
Past age 74, USPSTF gives a Grade I — meaning "the current evidence is insufficient to assess the balance of benefits and harms of screening mammography in women 75 years or older". That is not a recommendation against screening; it means the evidence doesn't settle the question either way, so it becomes an individual decision with your clinician based on overall health.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 75 with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Past age 74, USPSTF gives a Grade I — meaning "the current evidence is insufficient to assess the balance of benefits and harms of screening mammography in women 75 years or older". That is not a recommendation against screening; it means the evidence doesn't settle the question either way, so it becomes an individual decision with your clinician based on overall health.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Who is the best NBA player of all time?

Response: This can be discussed but it is often admitted that Michael Jordan is the best NBA player of all time.


Prompt: hey am I due for a pap smear??

Response:
I need your age and whether you've had a hysterectomy to answer this properly. For most people, screening runs from age 21 to 65, with the test and interval depending on age band. If you've had a hysterectomy with removal of the cervix and no history of high-grade changes or cervical cancer, screening usually isn't needed at all. What's your situation?

Source: USPSTF Cervical Cancer: Screening, August 2018.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 40-year-old and I've noticed unexplained rectal bleeding. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained rectal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My sister just turned 51, I have a 20 pack-year smoking history and quit 17 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 17 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 55, I have a 40 pack-year smoking history and quit 14 years ago. Do I qualify for lung cancer screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 55 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 53-year-old and I have a mole that's changed in bleeding and border and size over the past couple of months. How do I know if a mole is concerning?

Response:
Yes — any mole that is *changing* should be evaluated, and change in bleeding and border and size is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 41-year-old with a lump in the neck. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a lump in the neck is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My aunt just turned 60 with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Yes — at 60 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
Extract universities Moret studied at and his year of graduation for each, and put them in a bulleted list.

Moret was born in 1953 in Vevey Switzerland, and did his undergraduate studies at the École Polytechnique Fédérale de Lausanne (EPFL), graduating in 1975. He went on to graduate studies at the University of Tennessee, earning a Ph.D. in 1980. He then joined the faculty of the University of New Mexico, where he remained until 2006, when he moved to EPFL. He retired from EPFL in December 2016.

In 1996, Moret founded the ACM Journal of Experimental Algorithmics, and he remained editor in chief of the journal until 2003. In 2001, Moret founded the Workshop in Algorithms for Bioinformatics (WABI) and remains on the Steering Committee for the conference.

In 2018, Moret was elected as a Fellow of the International Society for Computational Biology, for his outstanding contributions to the fields of computational biology and bioinformatics.

Response:
* École Polytechnique Fédérale de Lausanne (EPFL) (graduated 1975)
* University of Tennessee (graduated 1980)


Prompt: I'm asking for my brother, who is 60. Is it time to check my prostate?

Response:
This one is genuinely a choice rather than a yes or no. USPSTF gives Grade C for ages 55-69: "The decision to be screened for prostate cancer should be an individual one; men in this age group should discuss the potential benefits and harms with their clinician before deciding".

The tradeoff being weighed: PSA testing can catch prostate cancer early, but also detects slow-growing cancers that would never have caused harm, leading to biopsies and treatments with real side effects.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What is the attraction in the United States for the Jeep Wrangler?

Response: The Jeep Wrangler represents the current version of the original Jeep Willys platform which was first released in 1940 for the U.S. Army.  The Jeep Wrangler platform first became available in 1987 and has become one of the most recognizable vehicles manufactured today.  The love Wrangler owners have for their vehicles stems from the utilitarian nature of the platform, the ability to remove the top and doors in warmer weather, the wide array of aftermarket modifications available, as well as its extensive off road capabilities directly off the showroom floor. Jeep enthusiasts, also known as “Jeepers,” often wave at each other when passing in opposite directions.  This tradition stemmed from the use of the Willy’s model in the US military where out of reverence and courtesy passing soldiers driving their Jeeps would wave or salute each other depending on rank.  This tradition continues today amongst Wrangler owners and has been affectionately dubbed the “Jeep Wave.”