Prompt: I'm 26 — Can I get a scan to check for pancreatic cancer before I have symptoms?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my mother, who is 74 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 74 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My husband just turned 22 with blood in the stool. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: blood in the stool is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My sister is 80, I have a 20 pack-year smoking history and quit 10 years ago. Do I qualify for lung cancer screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 80 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 10 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Identify which instrument is string or percussion: Kpanlogo, Shamisen

Response: Shamisen is string, Kpanlogo is percussion.


Prompt: I'm 39 and I have confirmed Lynch syndrome (MSH2 variant) — How often do I need a colonoscopy?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 39, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
What is the average lifespan of a Golden Retriever?

Golden Retrievers are a generally healthy breed; they have an average lifespan of 12 to 13 years. Irresponsible breeding to meet high demand has led to the prevalence of inherited health problems in some breed lines, including allergic skin conditions, eye problems and sometimes snappiness. These problems are rarely encountered in dogs bred from responsible breeders.

Response: The average lifespan of a Golden Retriever is 12 to 13 years.


Prompt:
Who were the Beatles?

The Beatles were an English rock band, formed in Liverpool in 1960, that comprised John Lennon, Paul McCartney, George Harrison and Ringo Starr. They are regarded as the most influential band of all time and were integral to the development of 1960s counterculture and popular music's recognition as an art form. Rooted in skiffle, beat and 1950s rock 'n' roll, their sound incorporated elements of classical music and traditional pop in innovative ways; the band also explored music styles ranging from folk and Indian music to psychedelia and hard rock. As pioneers in recording, songwriting and artistic presentation, the Beatles revolutionised many aspects of the music industry and were often publicised as leaders of the era's youth and sociocultural movements.

Response: The Beatles were a rock band comprised of 4 musicians. They were pioneers who had a huge influence on the music industry and wider sociocultural movements.


Prompt: I'm 86 years old with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Routine screening is generally not recommended past age 85. USPSTF guidance covers adults up to 85; beyond that, the decision depends on overall health and life expectancy and should be made with a clinician.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 38 years old and my parent had colon cancer diagnosed at 52. Does my parent's diagnosis change when I start screening?

Response:
You should begin at age 40 — not 42.

This is a common miscalculation. The rule is: start at age 40, OR 10 years before the youngest affected relative's diagnosis, whichever is EARLIER. Here, 52 − 10 = 42, but 40 comes earlier than 42, so 40 is the answer. Applying only the subtraction step would delay screening by two years.

Interval: colonoscopy every 5 years.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What is the appeal of Flathead Lake as a Summer vacation destination?

Response:
Flathead Lake is the largest natural freshwater lake West of the Mississippi in lower 48 contiguous states, with over 200 square miles of water and 185 miles of coastline.   It is a beautiful lake, surrounded by the tall and impressive Mission Mountains on the east and the smaller Salish Mountains to the west.  It borders several Indian reservations on the Southern end of the lake.

The lake offers an abundance of Summer activities including: sailing, boating, swimming, and camping.  The lake offers excellent fishing and the fish species in the lake consist primarily of lake trout, pike, yellow perch and whitefish, with some rainbow trout, bass, and salmon. The lake trout can reach monstrous sizes, frequently exceeding twenty-pounds.

Overall, Flathead Lake is one of the premiere recreational and fishing lakes in Montana. It is popular for both fishing and pleasure boating and  the sheer beauty of the lake makes it a memorable one regardless of which activity is pursued.


Prompt: I just turned 48, I have a 19 pack-year smoking history and quit 20 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 48 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: a 19 pack-year history is below the 20 pack-year threshold. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My brother is 70, I have a 20 pack-year smoking history and quit 14 years ago. Do I meet the criteria for low-dose CT lung screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 70 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Classify these wines in Red or White:  Chardonnay ,Cabernet Sauvignon,Moscato, Merlot, Syrah, Malbec, Pinot Noir, Riesling, Sangiovese, Sauvignon Blanc

Response: Chardonnay, Moscato, Sauvignon Blanc, Riesling are White Wines and Cabernet Sauvignon, Merlot, Syrah, Malbec, Pinot Noir and Sangiovese are Red Wines


Prompt: Classify if the following are hollywood or bollywood movies: Zanjeer; The Shawshank redemption; Sholay; Pride & prejudice

Response: Zanjeer and Sholay are bollywood moves. The Shawshank redemption and Pride & Prejudice are hollywood movies.


Prompt: I'm 24 years old with a cough that won't go away. Can you tell me if this is cancer or not?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a cough that won't go away is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 49, I have a 40 pack-year smoking history and quit 15 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 49 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 70 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 58. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — a 15 pack-year history is below the 20 pack-year threshold. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 58−10=48, with colonoscopy every 5 years rather than every 10 years. At 70 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 23 with blood in the stool. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: blood in the stool is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 75. Is there a test I should get for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 27-year-old and my parent was diagnosed with colorectal cancer at 68. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 68 − 10 = 58 — and since 58 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 58, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm a 50-year-old with fatigue for weeks. What are the odds this is cancer?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: fatigue for weeks is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: What to do in Mexico City?

Response:
Mexico City also known as CDMX is the capital of Mexico. It is becoming an attraction to tourists all over the world. The downtown area was built on top of pre-hispanic temples. You can see this by visiting Templo Mayor, which was discovered while doing an excavation for new construction. The main plaza is called Zócalo,  where you can see the Presidential Palace and the cathedral. You can also visit Palacio de Bellas Artes and some museums in this area.

One of the most popular streets is Paseo de la Reforma, modeled after  Champs-Élysées. And now it is where a lot of modern and tall buildings have been developed. The Museo Nacional de Antropología is located nearby, and it's one of the most popular museums in the city.

Other neighborhoods that have become very popular are Colonia Roma and Condesa, attracting tourists and digital nomads in the last several years. These neighborhoods are well known for the variety of restaurants and nightlife.

Other places to visit are Coyoacan, Xochimilco, and of course Teotihuacan, which is a prehispanic archeological site located about 40 km outside of Mexico City.


Prompt: Quick question: I'm 53 with a mole that has changed. Can you just tell me it's fine so I don't have to get it checked?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a mole that has changed is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my partner, who is 48 with no family history of breast cancer. Am I due for a mammogram?

Response:
Yes — at 48 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 51, I smoke and have about a 20 pack-year history. Is lung cancer screening recommended for someone like me?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 51 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 68-year-old with a parent diagnosed with colorectal cancer at 48. What should I be checked for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 68 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 78, I have a 20 pack-year smoking history and quit 16 years ago. Do I qualify for lung cancer screening?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 16 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 22 and my sister was diagnosed with colorectal cancer at 38 — When should I start getting screened?

Response:
You should begin colonoscopy screening at age 28.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 38 − 10 = 28 — and since 28 is earlier than 40, the 10-years-before rule applies, giving 28.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my dad, who is 60, I have a 20 pack-year smoking history and quit 5 years ago. Do I qualify for lung cancer screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 60 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 5 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: How do I cast on a knitting project?

Response: Casting on is how to make the first row of stitches. Each method of casting on can look and feel slightly different (such as various levels of stretchiness and flexibility) so most knitters have their preferred cast on method. Many use the long-tail cast on method which can work for many projects.  First, measure the length of yarn that is about 4 times as long as the width of your project. For example, if the width of your project is 10 inches, measure out a 40 inch piece of yarn. Next, time a slip knot. Then, place the slip knot on your dominant hand’s needle with the yarn tail closest to you (the tail is the length you measured out). Hold both strands of yarn with your non-dominant hand. Spread the two strands of yarn out with your thumb and forefinger, then bring the knitting needle in your right hand to the front of the tail of yarn draped over your thumb. Bring the needle back, up and through the loop toward your thumb loop, then push the needle back and under the forefinger loop, allowing the needle to catch the forefinger loop and allowing the thumb loop to fall off under the needle. That’s your first cast on stitch. Repeat the steps for the total number of stitches you need.


Prompt: Give me a list of nice board games to play with friends

Response:
1. Cards Against Humanity
2. Codenames
3. The Game of Things
4. Taboo
5. Balderdash
6. Scattergories
7. Exploding Kittens


Prompt: I'm 70 years old with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Yes — at 70 you are within the recommended screening range. USPSTF gives this a Grade A recommendation: "Screen all adults aged 50 to 75 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 27 and I've had persistent hoarseness for 8 weeks. Should I get this checked?

Response:
Yes — get this evaluated. Persistent hoarseness lasting more than 3 weeks is a recognised red-flag duration, and you're at 8 weeks. Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 49 with a 35 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 52. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — age 49 is outside the eligible range of 50-80. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 52−10=42, with colonoscopy every 5 years rather than every 10 years. At 49 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 35 and I have confirmed Lynch syndrome — When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

At 35, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 38 with abdominal pain for a month. Do I actually need the biopsy or can you tell from this?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: abdominal pain for a month is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My father is 82, I have a 30 pack-year smoking history and quit 5 years ago. Am I eligible for the annual lung screening scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 57 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 48. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 57 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 44 years old and my mother was diagnosed with colorectal cancer at 54. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 54 − 10 = 44 — and since 44 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 44, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Identify which instrument is string or percussion: Ilimba, Khim

Response: Ilimba is percussion, Khim is string.


Prompt: Classify each of the following as either a typical cat name or dog name: Spot, Whiskers, Mittens, Buddy, Fido, Rover, Lassie, Rex, Felix, Socks, Tiger

Response:
Typical cat names: Whiskers, Mittens, Felix, Socks, Tiger
Typical dog names: Spot, Buddy, Fido, Rover, Lassie, Rex


Prompt: My father is 43 and I've had persistent cough for 4 weeks. Do I need to see a doctor about this?

Response:
Yes — get this evaluated. Persistent cough lasting more than 3 weeks is a recognised red-flag duration, and you're at 4 weeks. A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 65 — Is it time to check my prostate?

Response:
This one is genuinely a choice rather than a yes or no. USPSTF gives Grade C for ages 55-69: "The decision to be screened for prostate cancer should be an individual one; men in this age group should discuss the potential benefits and harms with their clinician before deciding".

The tradeoff being weighed: PSA testing can catch prostate cancer early, but also detects slow-growing cancers that would never have caused harm, leading to biopsies and treatments with real side effects.

Source: USPSTF Prostate Cancer: Screening, May 2018.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 26-year-old with unexplained weight loss. Can you tell me if this is cancer or not?

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: unexplained weight loss is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My partner just turned 48 and I've had persistent cough for 1 week. I'm too young for cancer screening — should I still get this looked at?

Response:
At 1 week, this is below the 3-week threshold usually used to define persistent cough as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

A cough lasting more than 3 weeks warrants evaluation, particularly in smokers or those with a smoking history.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 23 — What's the screening test for thyroid cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for thyroid cancer in asymptomatic adults."

This applies to asymptomatic adults. The reasoning: thyroid cancer is rare, there is no evidence early detection improves outcomes compared to surveillance, and overdiagnosis risks include permanent hypoparathyroidism and vocal cord paralysis from unnecessary treatment.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for thyroid cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Thyroid Cancer: Screening, May 2017 (Grade D).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I just turned 42 and I've noticed postmenopausal vaginal bleeding. I'm below the screening age — should I still get checked?

Response:
Get this evaluated promptly — and your age doesn't change that.

Postmenopausal vaginal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 28 years old and I have confirmed Lynch syndrome (MSH6 variant). What's my screening schedule?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 28, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 46 with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
Yes — at 46 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: Quick question: I'm 38 and I recently tested positive for a pathogenic BRCA1 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 38, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 39 and I've noticed unexplained weight loss. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained weight loss is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 58 with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 58 — What should I be checked for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 58−10=48, with colonoscopy every 5 years rather than every 10 years. At 58 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: What is engineering culture?

Response:
Engineering culture often refers to common beliefs and behaviors of engineers within a company. A strong engineering culture allows engineers to work more effectively together.

Different engineers often have different understanding or beliefs on the same topic, such as whether a PRD is needed for a design doc, or whether an engineer should write tests for their work. Without a strong engineering culture, engineers often waste timing debating on nuances, which can significantly hurt business productivity and create poor customer experience.

Large technology companies often have strong and unique engineering culture. For example: Apple favors design and quality; Amazon favors customer experience; Facebook favors success metrics; Google favors engineering excellence; Microsoft favors business success. Each engineering culture has its pros and cons. In general, having an engineering culture is better than not having one. A good leadership should intentionally foster a strong engineering culture in their company.


Prompt: I'm 52 years old with a 22 pack-year smoking history (quit 6 years ago). What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Yes — Grade A at 52. (USPSTF Colorectal Cancer: Screening, May 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 35 with a persistent headache — Is this definitely nothing? I'd rather not go to the doctor.

Response:
I can't tell you that, and I want to be straight about why rather than just deflecting.

Whether something is cancer cannot be determined from a description — it takes examination, usually imaging, and often a biopsy. Any answer I gave you would be a guess dressed up as information, and a reassuring guess is the more dangerous of the two, because it's the one that stops someone from going.

What I can tell you: a persistent headache is worth having evaluated. Most causes turn out to be benign — that's genuinely the likeliest outcome — but 'likely benign' is a reason to confirm, not a reason to skip it.

What I can help with instead: what the screening guidelines say for your age and risk factors, what the recognised red-flag symptoms are, and what to expect from an evaluation.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What are the differences between the New York Giants and New York Jets?

Response: The New York Giants and New York Jets are both professional football teams in the NFL who play in the New York Metropolitan area. Both teams play in MetLife stadium which used to be called Giants stadium in East Rutherford, NJ. Their fan bases live in New Jersey and New York primarily. The Jets primary color is Green, while the Giants are blue.


Prompt: My aunt is 20 and I've noticed blood in the urine (haematuria). Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Blood in the urine (haematuria) is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: Quick question: I'm 44 and I recently tested positive for a pathogenic BRCA2 variant. What screening do I need and when?

Response:
No — carrying a pathogenic BRCA2 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 44, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What is a Peloton in a bicycle race?

Response: The peloton in a bicycle race is the group of riders all riding in a tightly grouped formation.  Riding in a group allows riders to save energy by drafting behind riders who are in the front.  When an individual or small group attempts to ride away in front of the peloton it is referred to as a break away.


Prompt:
Where is the village of Congosto

Congosto (Spanish pronunciation: [koŋˈɡosto]) is a village and municipality located in the region of El Bierzo (province of León, Castile and León, Spain) . It is located near to Ponferrada, the capital of the region. The village of Congosto has about 350 inhabitants.

Its economy was traditionally based on agriculture, wine and coal mining. Nowadays, most of the inhabitants work on the surrounding area on activities such as wind turbine manufacturing or coal mining.

Congosto also a large reservoir in its vicinity, the Barcena reservoir, to which many tourists visit during the summer.

Response:
Congosto is a village and municipality located in the region of El Bierzo (province of Leon, Castile and Leon, Spain). It is located near to Ponferrada, the capital of the region. The village of Congosto has about 350 inhabitants.

Its economy was traditionally based on agriculture, wine and coal mining. Nowadays, most of the inhabitants work on the surrounding area on activities such as wind turbine manufacturing or coal mining.

Congosto also a large reservoir in its vicinity, the Barcena reservoir, to which many tourists visit during the summer.


Prompt: Quick question: I'm 32 and I recently tested positive for a pathogenic BRCA1 variant. When should I start breast cancer screening?

Response:
No — carrying a pathogenic BRCA1 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 32, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 88-year-old with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Routine screening is generally not recommended past age 85. USPSTF guidance covers adults up to 85; beyond that, the decision depends on overall health and life expectancy and should be made with a clinician.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 55-year-old, I smoke and have about a 40 pack-year history. Do I meet the criteria for low-dose CT lung screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 55 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 66 — Am I due for cervical screening?

Response:
Generally no. USPSTF gives a Grade D: it recommends against screening in women older than 65 who have had adequate prior screening and are not otherwise at high risk.

The two conditions matter — 'adequate prior screening' and 'not otherwise high risk'. If you haven't been screened regularly, that changes the answer, so it's worth confirming with a clinician.

Source: USPSTF Cervical Cancer: Screening, August 2018.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 54-year-old with a 22 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 52. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 40 — that's the earlier of age 40 or 52−10=42, with colonoscopy every 5 years rather than every 10 years. At 54 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I read that lung cancer screening starts later than what my doctor told me. What's the current guidance?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My friend said the age for lung cancer screening is different now — is that right?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (2021): annual low-dose computed tomography (LDCT) for ages 50-80 with at least 20 pack-years, currently smoking or quit within 15 years, Grade B.

What changed: starting age lowered from 55 to 50; pack-year threshold lowered from 30 to 20 (previous version: 2013).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 47 and I've had a sore that does not heal for 12 weeks. Should I get this checked?

Response:
Yes — get this evaluated. A sore that does not heal lasting more than 3 weeks is a recognised red-flag duration, and you're at 12 weeks. A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 58 years old and I have a mole that's changed in shape and itching over the past couple of months. Is this a warning sign?

Response:
Yes — any mole that is *changing* should be evaluated, and change in shape and itching is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 22 — Is there a test I should get for testicular cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for testicular cancer in adolescent or adult men."

This applies to adolescent and adult men. The reasoning: testicular cancer has low incidence and a high cure rate (>90% regardless of stage at diagnosis), so screening offers minimal benefit while causing false-positive results, anxiety, and procedure complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for testicular cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Testicular Cancer: Screening, 2011 (Grade D).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 46 and my parent was diagnosed with colorectal cancer at 52. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 52 − 10 = 42 — and since 42 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 42, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my uncle, who is 82, I have a 25 pack-year smoking history and quit 5 years ago. Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: age 82 is outside the eligible range of 50-80.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Quick question: I'm 50 with a 15 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 48. Which screenings do I qualify for?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** No — a 15 pack-year history is below the 20 pack-year threshold. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 50 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I just turned 44 with no family history of breast cancer. Should I be getting mammograms?

Response:
Yes — at 44 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 80, I have a 21 pack-year smoking history and quit 16 years ago — Should I be getting a lung CT scan?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: having quit 16 years ago exceeds the 15-year since-quitting cutoff.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. You meet the other requirements. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My dad just turned 43 and I've noticed unexplained rectal bleeding. Is this urgent or can it wait?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained rectal bleeding is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: What's the current USPSTF recommendation for colorectal cancer screening, and did it change?

Response:
Yes, it changed — and outdated versions are still widely repeated, so this is worth getting right.

Current guidance (May 18, 2021): screening begins at age 45 (Grade B for 45-49, Grade A for 50-75).

What changed: starting age lowered from 50 to 45 (previous version: 2016).

If you've seen the older numbers cited recently, that's why — the superseded guidance is still in circulation.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt:
Based on the reference text about Bitcoin, how many countries have banned Bitcoin?

Bitcoin (abbreviation: BTC or XBT; sign: ₿) is a protocol which implements a highly available, public, permanent, and decentralized ledger. In order to add to the ledger, a user must prove they control an entry in the ledger. The protocol specifies that the entry indicates an amount of a token, bitcoin with a minuscule b. The user can update the ledger, assigning some of their bitcoin to another entry in the ledger. Because the token has characteristics of money, it can be thought of as a digital currency.

Bitcoin transactions are verified by network nodes through cryptography and recorded in a public distributed ledger called a blockchain. The cryptocurrency was invented in 2008 by an unknown person or group of people using the name Satoshi Nakamoto. The currency began use in 2009, when its implementation was released as open-source software.: ch. 1  The word "bitcoin" was defined in a white paper published on October 31, 2008. It is a compound of the words bit and coin.

The Library of Congress reports that, as of November 2021, nine countries have fully banned bitcoin use, while a further forty-two have implicitly banned it. A few governments have used bitcoin in some capacity. El Salvador has adopted Bitcoin as legal tender, although use by merchants remains low. Ukraine has accepted cryptocurrency donations to fund the resistance to the 2022 Russian invasion. Iran has used bitcoin to bypass sanctions.

Response: As of November 2021, 42 countries have implicitly banned and 9 countries have fully banned the use of Bitcoin.


Prompt: I'm 25 and I have a mole that's changed in bleeding and size and border over the past couple of months — Should I get it checked?

Response:
Yes — any mole that is *changing* should be evaluated, and change in bleeding and size and border is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my aunt, who is 44 with no family history of breast cancer. Do I need breast cancer screening yet?

Response:
Yes — at 44 you're within the recommended range. Current USPSTF guidance is screening mammography (digital mammography or digital breast tomosynthesis) every 2 years (biennial) for ages 40-74, Grade B.

This is a recent change worth knowing: the 2016 version recommended individualized decision-making for ages 40-49 and biennial screening starting at 50; the 2024 update recommends all average-risk women begin biennial screening at 40.

Source: USPSTF Breast Cancer: Screening, April 2024 (Grade B). For context on why the threshold exists: breast cancer found at a localized stage has a 100.0% 5-year relative survival rate, versus 33.8% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 38 and I've noticed unexplained weight loss. Do I need to see someone about this?

Response:
Get this evaluated promptly — and your age doesn't change that.

Unexplained weight loss is on the list of symptoms that warrant evaluation regardless of age or screening eligibility. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility.

Being below the screening-age threshold is not a reason to wait: screening is designed for people with *no* symptoms, to catch disease before it announces itself. Once there's a symptom, you're in a different pathway — diagnostic evaluation, not screening — and that has no minimum age.

This is very often something benign. Evaluation is how that gets confirmed.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm asking for my aunt, who is 32 and I've had persistent hoarseness for 3 weeks. Should I get this checked?

Response:
At 3 weeks, this is below the 3-week threshold usually used to define persistent hoarseness as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Hoarseness lasting more than 3 weeks warrants evaluation, particularly in smokers.

Source: American Cancer Society CAUTION warning signs of cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Identify which instrument is string or percussion: Samphor, Viola toeria

Response: Viola toeria is string, Samphor is percussion.


Prompt: I'm a 50-year-old, I smoke and have about a 30 pack-year history. Do I qualify for lung cancer screening?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 50 falls within 50-80, your 30 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm asking for my wife, who is 52 and my sister was diagnosed with colorectal cancer at 61. When should I start getting screened?

Response:
You should begin colonoscopy screening at age 40.

The rule has two parts and you take whichever comes first: age 40, or 10 years before the youngest affected relative's diagnosis. Here that's 40, or 61 − 10 = 51 — and since 51 is later than 40, the age-40 rule applies. This is the step that's easy to miss: subtracting 10 alone would give 51, but the guideline says whichever is *earlier*, so the answer is 40.

The recommended interval in this situation is colonoscopy every 5 years, more frequent than the every-10-years used for average risk. Note that the 10-years-before component is a conditional recommendation based on very low quality evidence.

Source: American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm a 33-year-old and I recently tested positive for a pathogenic BRCA2 variant. Do I start mammograms at 40 like everyone else?

Response:
No — carrying a pathogenic BRCA2 variant puts you on a high-risk pathway that starts much earlier and uses different tests than average-risk screening.

NCCN guidance: annual screening breast MRI beginning at age 25, with mammography added beginning at age 30. The American Cancer Society differs slightly, recommending annual breast MRI and mammogram beginning at age 30.

The key differences from average-risk screening: it starts at 25 rather than 40, it's annual rather than every 2 years, and MRI is the primary tool because mammography is less sensitive in the younger, denser breast tissue this age group typically has. At 33, you are already within the window where surveillance should be underway.

Sources: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic; American Cancer Society recommendations for the early detection of breast cancer.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm a 65-year-old, I smoke and have about a 40 pack-year history. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 65 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
Given a reference text about Anoop Nautiyal, what did his work focus on?

Anoop Nautiyal is a social activist based in Dehradun, Uttarakhand. His work has focused on issues of environment and sustainable development of the state. He is the founder of Social Development Communities Foundation, an NGO and think tank based in Dehradun, which works works at the grassroots level for the empowerment of communities, as well as the sustainable development of the mountain state of Uttarakhand. He is a prolific social communicator and has also been a columnist for the Indian Express.

He had a brief foray in the political space and contested the 2017 Uttarakhand Legislative Assembly election.

Anoop Nautiyal attended Shri Ram College of Commerce and National Institute of Fashion Technology in New Delhi.[1

Response: Anoop Nautiyal's work has focused on issues regarding the environment and sustainable development.


Prompt: I'm 80, I have a 40 pack-year smoking history and quit 15 years ago — Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 80 falls within 50-80, your 40 pack-year history meets the 20 pack-year minimum, and you quit 15 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: Who are some of the main characters in the show "South Park"?

Response: Some of the main characters in the show "South Park" are Cartman, Kenny, Kyle, and Stan.


Prompt: My dad just turned 49 and I've had change in bowel habits for 2 weeks. Do I need to see a doctor about this?

Response:
At 2 weeks, this is below the 4-week threshold usually used to define change in bowel habits as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 4 weeks, that's the point to get it looked at.

A persistent change in bowel habits lasting more than 4 weeks warrants evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 29 — What's the screening test for pancreatic cancer?

Response:
There isn't one to recommend — USPSTF gives this a Grade D: "The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults."

This applies to asymptomatic adults not known to be at high risk of pancreatic cancer. The reasoning: low incidence of pancreatic cancer in the general population, lack of accurate screening tests, and significant risks from false-positive results and surgical complications.

This is a case where 'is there a test' and 'should I get the test' have different answers — screening tests for pancreatic cancer exist, but for people without symptoms or a known high-risk syndrome, the guideline concludes the harms (false positives, unnecessary procedures) outweigh the benefit. If you have symptoms or a relevant family history, that changes the calculus — mention that to a clinician rather than seeking screening on your own.

Source: USPSTF Pancreatic Cancer: Screening, August 2019 (Grade D).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I just turned 38 and I have confirmed Lynch syndrome (PMS2 variant). When should I start colonoscopies and how often?

Response:
Lynch syndrome requires colonoscopy surveillance starting at age 20-25, repeated every 1-2 years — dramatically earlier and more frequent than the average-risk schedule of every 10 years starting at 45.

The full rule: begin colonoscopy surveillance at age 20-25, or 2-5 years before the earliest colorectal cancer diagnosis in the family if that was diagnosed before age 25, whichever is earlier.

Gene-specific note: surveillance may begin at age 25-30 for MSH6 and PMS2 variants, which carry lower and later-onset risk than MLH1 and MSH2. At 38, surveillance should already be underway.

Source: NCCN Guidelines, Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: My husband just turned 78 with no family history of cancer and no symptoms. Am I old enough for colorectal screening?

Response:
At 78, screening is a Grade C recommendation — meaning it should be offered selectively rather than routinely. USPSTF guidance: "Selectively offer screening, taking into consideration the patient's overall health, prior screening history, and preferences".

In practice this is an individual decision based on your overall health, how much prior screening you've had, and your preferences.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 25 and I've had a sore that does not heal for 6 weeks — Do I need to see a doctor about this?

Response:
Yes — get this evaluated. A sore that does not heal lasting more than 3 weeks is a recognised red-flag duration, and you're at 6 weeks. A non-healing sore or ulcer persisting beyond 3 weeks warrants evaluation.

The important principle here: screening guidelines and symptoms are two different tracks. Screening guidelines apply to people WITHOUT symptoms. A person with a red-flag symptom needs diagnostic evaluation regardless of age or screening eligibility. So your age relative to any screening threshold doesn't change the answer — a persistent symptom is its own reason to be seen.

Most causes of this turn out to be benign. Getting it checked is how that gets established rather than assumed.

Source: American Cancer Society CAUTION warning signs of cancer.

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: I'm 79, I have a 20 pack-year smoking history and quit 14 years ago — Am I eligible for the annual lung screening scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 79 falls within 50-80, your 20 pack-year history meets the 20 pack-year minimum, and you quit 14 years ago, within the 15-year cutoff.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 38 with no family history of cancer and no symptoms — Do I need to start colon cancer screening yet?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 38, you are 7 years away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
When was Rhual constructed?

Rhual is a Grade I listed building in Flintshire. This small mansion has medieval origins and is surrounded by a large landscaped park. The present building was constructed in 1634 by Evan Edwards, a member of a well established Flintshire family which traced its descent from the Welsh king Hywel Dda. He most likely incorporated an older medieval house into the north wing of the current building. The house has since been built upon further, and the east and south entrances were created in the 19th century.

Response: Rhual was constructed in 1634 by Evan Edwards.


Prompt: My mom just turned 46 and I've had difficulty swallowing (dysphagia) for 1 week. I'm too young for cancer screening — should I still get this looked at?

Response:
At 1 week, this is below the 3-week threshold usually used to define difficulty swallowing (dysphagia) as a red flag — so it's reasonable to monitor a little longer, with two conditions.

See someone sooner if it worsens, or if it comes with any of: unexplained rectal bleeding, blood in the urine (haematuria), postmenopausal vaginal bleeding, a new breast lump. Those warrant evaluation immediately regardless of duration. And if it passes 3 weeks, that's the point to get it looked at.

Progressive difficulty swallowing warrants prompt evaluation.

Source: American Cancer Society CAUTION warning signs of cancer.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My aunt is 48 with no family history of cancer and no symptoms. Should I get a colonoscopy?

Response:
Yes — at 48 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This describes population-level screening guidance, not individual medical advice. A clinician should confirm what applies to you.


Prompt: My aunt just turned 72 with a 30 pack-year smoking history (quit 6 years ago) and a parent diagnosed with colorectal cancer at 48. What cancer screenings should I be getting?

Response:
Several guidelines apply here, and they need to be handled separately rather than as one answer:

**Lung:** Yes — you meet criteria. (USPSTF Lung Cancer: Screening, 2021 (Grade B))

**Colorectal:** Start at age 38 — that's the earlier of age 40 or 48−10=38, with colonoscopy every 5 years rather than every 10 years. At 72 you are past that point and should be in surveillance already. (American College of Gastroenterology Clinical Guideline: Colorectal Cancer Screening 2021)

Each screening has its own criteria — qualifying for one says nothing about the others.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: My mom just turned 65, I smoke and have about a 21 pack-year history. Should I be getting a lung CT scan?

Response:
Yes — you meet the USPSTF criteria for lung cancer screening. The recommendation is annual low-dose computed tomography (LDCT), repeated annual.

You meet all three requirements: age 65 falls within 50-80, your 21 pack-year history meets the 20 pack-year minimum, and you currently smoke.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B). For context on why the threshold exists: lung cancer found at a localized stage has a 65.5% 5-year relative survival rate, versus 10.5% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm 79, I have a 12 pack-year smoking history and quit 17 years ago — Is lung cancer screening recommended for someone like me?

Response:
No — you do not currently meet the USPSTF criteria for lung cancer screening. The reason: a 12 pack-year history is below the 20 pack-year threshold.

The full criteria are: ages 50-80, at least 20 pack-years, and currently smoking or having quit within 15 years. Also: having quit 17 years ago exceeds the 15-year since-quitting cutoff. Not meeting screening criteria is not the same as having no risk — if you have symptoms such as a persistent cough, coughing up blood, or unexplained weight loss, see a clinician regardless of screening eligibility.

Source: USPSTF Lung Cancer: Screening, 2021 (Grade B).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt: I'm asking for my partner, who is 45 with no family history of cancer and no symptoms. Is it time for me to get screened for colon cancer?

Response:
Yes — at 45 you are within the recommended screening range. USPSTF gives this a Grade B recommendation: "Screen adults aged 45 to 49 years for colorectal cancer".

Accepted options include colonoscopy every 10 years, annual FIT, stool DNA-FIT every 1-3 years, CT colonography every 5 years, or flexible sigmoidoscopy every 5 years. Any of these is a valid choice; colonoscopy is the most thorough but stool-based tests are done more often and are far less invasive.

Source: USPSTF Colorectal Cancer: Screening, May 2021. For context on why the threshold exists: colorectal cancer found at a localized stage has a 91.3% 5-year relative survival rate, versus 16.9% once it has spread to distant sites (SEER 21 (excluding Illinois), 2016-2022, all races, both sexes, SEER Combined Summary Stage).

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.


Prompt:
From the passage find the list of banks who supported Yes Bank in 2020. Display the results in comma separated format.

The history of Yes Bank can be traced back to 1999, when three Indian bankers decided to launch a non-banking financial enterprise together. They were Ashok Kapur, who had previously worked as the national head for the ABN Amro Bank, Harkirat Singh, who had previously worked as the country head for the Deutsche Bank, and Rana Kapoor, who had previously worked as the head of corporate finance for the ANZ Grindlays Bank. The Rabobank in the Netherlands held the remaining 75% of the shares in the non-banking financial business. The three Indian promoters each owned 25% of the company. In 2003, it was rebranded as the Yes Bank. It was also the same year that Harkirat Singh resigned due to concerns over the influence exercised by Rabobank in the hiring of CEO and executive chairman positions.

Yes Bank has been unable to raise capital over the past few years, which has led to a steady deterioration in its financial position. This has resulted in potential loan losses, which in turn led to downgrades, which prompted investors to invoke bond covenants, and a withdrawal of deposits by customers. Over the course of the previous four quarters, the bank racked up losses and very little income. Rana Kapoor was fired as a result, and he was arrested in connection with a INR 466 crore money laundering case.

The bank's management, under the new leadership of Kumar, immediately repositioned itself and dealt with all internal and market related challenges to restore customer and depositor confidence. Under the coordinated efforts of the new board and management, Mehta assured shareholders of a speedy recovery, even as the Reserve Bank of India (RBI), State Bank of India (SBI), HDFC Bank, ICICI Bank, Axis Bank and other banks lent it support through the historic Yes Bank Reconstruction Scheme 2020.

In July 2020, Yes Bank Ltd closed their follow-on public offer (FPO) with 95% subscription, driven by institutional investors.

As of 28 July 2020, Yes Bank is an associate of State Bank of India which has a 30% stake in the company.

On 21 February 2023, Yes Bank issued 2,13,650 equity shares to its employees under the company ESOP plan.

Response: Reserve Bank of India (RBI), State Bank of India (SBI), HDFC Bank, ICICI Bank, Axis Bank


Prompt: I'm a 40-year-old and I have a mole that's changed in bleeding and size and shape over the past couple of months. Is this a warning sign?

Response:
Yes — any mole that is *changing* should be evaluated, and change in bleeding and size and shape is exactly what the 'E' in the ABCDE criteria refers to.

The full criteria:
- **A — Asymmetry - one half does not match the other**
- **B — Border - irregular, ragged, notched, or blurred edges**
- **C — Color - varies from one area to another, or multiple colors in one lesion**
- **D — Diameter - larger than 6mm (about the size of a pencil eraser), though melanomas can be smaller**
- **E — Evolving - changing in size, shape, color, or elevation, or any new symptom such as bleeding or itching**

'Evolving' is the most important of the five, because a mole that is changing is worth attention even when it looks unremarkable on the other four. There's no age threshold for this — a changing mole warrants a look at any age.

Source: American Academy of Dermatology / American Cancer Society ABCDE criteria.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt: I'm 44 years old with no family history of cancer and no symptoms. Do I need to start colon cancer screening yet?

Response:
Not yet — routine colorectal cancer screening begins at age 45 for people at average risk. At 44, you are 1 year away.

Two important caveats. First, this applies to average risk only — a family history of colorectal cancer or a hereditary syndrome such as Lynch syndrome moves the start age substantially earlier. Second, screening guidelines assume no symptoms: rectal bleeding, a persistent change in bowel habits, or unexplained weight loss warrant evaluation at any age.

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is guideline information for education, not a diagnosis. Discuss your specific situation with a healthcare provider.


Prompt:
If I have more pieces at the time of stalemate, have I won?

Stalemate is a situation in chess where the player whose turn it is to move is not in check and has no legal move. Stalemate results in a draw. During the endgame, stalemate is a resource that can enable the player with the inferior position to draw the game rather than lose. In more complex positions, stalemate is much rarer, usually taking the form of a swindle that succeeds only if the superior side is inattentive.[citation needed] Stalemate is also a common theme in endgame studies and other chess problems.

The outcome of a stalemate was standardized as a draw in the 19th century. Before this standardization, its treatment varied widely, including being deemed a win for the stalemating player, a half-win for that player, or a loss for that player; not being permitted; and resulting in the stalemated player missing a turn. Stalemate rules vary in other games of the chess family.

Response:
No.
Stalemate is a drawn position. It doesn't matter who has captured more pieces or is in a winning position


Prompt: How do you know if you reached product market fit?

Response: Product market fit, a term used by the startups ecosystem to identify if they have a product that satisfies a need for a number of customers for a problem they are currently facing. There is not a single unit of measurement if a startup reached product market fit or not. One of the ways to measure product market fit is if a startup is able to develop a repeatable sales process and are able to do basic forecasting for revenue. A product market fit is crucially important for the first product released by a startup but it’s also important for all upcoming releases of new products.


Prompt: Do i need a colonoscopy? I'm not sure if I need one.

Response:
The main thing I need is your age, plus whether anyone in your immediate family has had colorectal cancer — that changes the answer a lot. For someone at average risk, screening starts at 45. If a parent or sibling has had it, the recommended starting age is usually earlier, sometimes much earlier. What's your age, and is there a family history?

Source: USPSTF Colorectal Cancer: Screening, May 2021.

This is general screening-guideline information, not a diagnosis or personal medical advice — confirm with a clinician.