# STEM BIO-AI Tier Decision Table Operational meaning of each tier for institutional decision-makers. ## Tier Definitions and Institutional Actions | Tier | Score | Trust Signal | Institutional Action | Permitted Scope | |------|-------|-------------|---------------------|-----------------| | T0 Rejected | 0-39 | Trust not established | Do not integrate. Do not rely without repository-specific expert validation. Clinical use prohibited. No exceptions. | None | | T1 Quarantine | 40-54 | High risk, structurally interesting | Educational and exploratory use only. Air-gapped systems. No patient-adjacent data. Human review of all outputs. Time-limited deployment with re-evaluation. | Scope A (Research Only) | | T2 Caution | 55-69 | Bounded review candidate | Supervised non-clinical use. Governance overlay required if deploying. Continuous monitoring. No autonomous clinical decision support. | Scope A (Research Only) | | T3 Review | 70-84 | Supervised pilot eligible | Supervised clinical pilot candidate. Full governance controls required. Human-in-the-loop mandatory. Regulatory pre-submission recommended. | Scope A + B (Supervised Pilot) | | T4 Approved | 85-100 | Operational trust candidate | Verified deployment eligible. Full governance layer required. Regulatory submission completed or in progress. Domain validation mandatory. | Scope A + B + C (D: regulatory) | ## Governance Overlay Interaction | Base Tier | Overlay Verdict | Operational Interpretation | |-----------|----------------|--------------------------| | T0 | NONE | No trust, no governance. Standard T0. | | T0 | BOUNDED | Repo still low-trust, but bounded structural remediation is real. Does NOT justify T3 promotion. | | T0 | STRONG | Governance is real but native maturity gap remains critical. Re-audit after remediation. | | T2 | STRONG | Meaningful maturity + governance. Formal T3 requires base score math, not overlay. | | T3 | STRONG | Strong candidate for supervised pilot with full governance. | ## T0_HARD_FLOOR Override When H3 (fully autonomous clinical) AND H4 (AGI-level claims) both trigger: - Final Score = 0, Tier = T0, USE_SCOPE = None - No exceptions. No governance overlay can override. - Hard floor notice mandatory in report. ## CA-DIRECT Redistribution Warning When Stage 2 = N/A AND CA-DIRECT AND Stage 1 >= 70 AND Stage 3 <= 40: - Score is mathematically valid but potentially misleading - README quality may mask engineering deficiency - Mandatory advisory in Final Judgment - Reviewers should weight Stage 3 independently for clinical decisions