Datasets:

ClarusC64
/

clinical-therapeutic-pathway-adaptive-navigation-v0.1

id stringclasses 10 values	pathway_anchor stringclasses 10 values	patient_profile stringclasses 10 values	current_position_summary stringclasses 10 values	invariant_signature stringclasses 5 values	predicted_next_basin stringclasses 6 values	risk_flags stringclasses 8 values	constraints_and_contraindications stringclasses 7 values	candidate_actions stringclasses 10 values	recommended_action stringclasses 6 values	action_plan_microsteps stringclasses 10 values	rationale_trace stringclasses 10 values	navigation_label stringclasses 3 values	failure_signature stringclasses 4 values	constraints stringclasses 1 value	gold_checklist stringclasses 10 values
TPM-NAV-001	RA biologic initiation	48F, RA active	CRP 14; pain 4; fatigue 5; US mid; slope slowing	response_slope_collapse	stabilization_basin	infection_risk=0	avoid_steroid_long=1	stay_course; adjust_dose; switch_class; add_support_module	adjust_dose	1) optimize dosing 2) recheck CRP/US at 6 weeks 3) add sleep support	Slope slowing suggests on-ramp optimization not a class switch	coherent_navigation	none	Under 220 words.	1 dose optimize
TPM-NAV-002	IBD plateau then biologic decision	32M, IBD flare	Calprotectin 650 flat; stool 6 flat; MRI mid	response_slope_collapse	delayed_recovery_basin	organ_risk=1	avoid_long_steroids=1	start_biologic; extend_steroids; pause_observe; add_support_module	switch_class	1) start biologic 2) monitor calprotectin at 4-6 weeks 3) nutrition support	Plateau means current pathway is not moving. Start new lever	coherent_navigation	none	Under 220 words.	1 switch lever
TPM-NAV-003	Migraine preventive tradeoff	35F, migraine	Attacks 2; fatigue 6; function down	adverse_tradeoff_signature	oscillation_basin	falls_risk=0	avoid_sedating_agents=1	stay_course; adjust_dose; switch_class; add_support_module; deescalate_exit_loop	switch_class	1) stop current agent 2) select alternative preventive 3) track attacks and fatigue weekly	Tradeoff predicts instability. Move to a different lever	coherent_navigation	none	Under 220 words.	1 exit tradeoff
TPM-NAV-004	Opioid tolerance loop	62M, chronic pain	Pain returns despite dose increases	response_slope_collapse	tolerance_loop_basin	resp_dep_risk=1	avoid_opioid_escalation=1	adjust_dose; switch_class; deescalate_exit_loop; add_support_module	deescalate_exit_loop	1) start taper plan 2) nonopioid analgesic 3) physio and CBT pain	Tolerance basin. Escalation breaks coherence. Exit loop	coherent_navigation	tolerance-loop-repeat	Under 220 words.	1 must taper
TPM-NAV-005	Post-viral early worsening	34F, post-viral	HRV down; fatigue flat; steps down	volatility_spike	deterioration_basin	overexertion=1	none	stay_course; pause_observe; add_support_module; deescalate_exit_loop	pause_observe	1) reduce load 2) sleep protocol 3) recheck HRV and steps in 7 days	Spike suggests mismatch. Pause and stabilize before escalation	coherent_navigation	none	Under 220 words.	1 pause to stabilize
TPM-NAV-006	Autoimmune GI missed doses	41F, autoimmune GI	Relapse after missed dosing	on_off_coupling_signature	oscillation_basin	infection_risk=1	none	stay_course; adjust_dose; add_support_module; switch_class	add_support_module	1) adherence cue redesign 2) drug level checks 3) infection monitoring	Oscillation driven by exposure gap. Fix adherence before switching	coherent_navigation	none	Under 220 words.	1 fix adherence
TPM-NAV-007	Depression slow gain	29F, MDD	PHQ down 3 at week4; sleep up slightly	delayed_threshold_signature	delayed_recovery_basin	suicidality=0	avoid_polypharmacy=1	stay_course; add_support_module; switch_class	stay_course	1) continue CBT 2) behavioral activation 3) sleep anchor	Delayed signature. Stay course and support inputs	coherent_navigation	none	Under 220 words.	1 stay
TPM-NAV-008	Hypertension tradeoff dizziness	63F, HTN	SBP down but dizziness rising	adverse_tradeoff_signature	mixed_uncertain	falls_risk=1	avoid_over_titration=1	adjust_dose; add_support_module; switch_class; pause_observe	adjust_dose	1) reduce or retime dose 2) home BP log 3) review electrolytes	Keep BP gains while resolving side effect	partially_coherent	tradeoff	Under 220 words.	1 manage side effect
TPM-NAV-009	Cancer chemo toxicity constraint	59F, breast cancer	Marker down but neutrophils low	adverse_tradeoff_signature	mixed_uncertain	infection_risk=1	none	adjust_dose; add_support_module; switch_class; urgent_escalation	add_support_module	1) growth factor support 2) CBC monitoring 3) revisit regimen if repeated	Preserve response while stabilizing toxicity	coherent_navigation	toxicity	Under 220 words.	1 support toxicity
TPM-NAV-010	Incorrect protocol reflex	62M, opioid tolerance loop	Pain returns with escalation history	response_slope_collapse	tolerance_loop_basin	resp_dep_risk=1	avoid_opioid_escalation=1	adjust_dose; deescalate_exit_loop; add_support_module	adjust_dose	1) increase opioid 2) add sedative 3) wait	Ignores tolerance signature and constraints	incoherent_navigation	tolerance-loop-repeat	Under 220 words.	1 must not escalate

What this dataset tests

Whether a model can choose the best next pathway move
based on manifold position and invariant branch signatures.

Navigation actions

stay_course
adjust_dose
switch_class
pause_observe
add_support_module
deescalate_exit_loop
urgent_escalation

Outputs

one recommended action
2 to 3 microsteps
one navigation label

Labels

coherent_navigation
partially_coherent
incoherent_navigation

Typical failures

protocol reflex that ignores invariant signatures
repeating tolerance loops
ignoring contraindications
switching classes when the real issue is exposure gap

Suggested prompt wrapper

System

You navigate a therapeutic pathway.

User

Current Position
{current_position_summary}

Invariant Signature
{invariant_signature}

Predicted Basin
{predicted_next_basin}

Risk Flags
{risk_flags}

Constraints
{constraints_and_contraindications}

Return

one recommended action
2 microsteps
one label

Citation

ClarusC64 dataset family

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