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passage: title: Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2 abstract: For almost two years, the COVID-19 pandemic has constituted a major challenge to human health, particularly due to the lack of efficient antivirals to be used against the...
898
passage: title: Political Secularism and Muslim Integration in the West: Assessing the Effects of the French Headscarf Ban abstract: In response to rising immigration flows and the fear of Islamic radicalization, several Western countries have enacted policies to restrict religious expression and emphasize secularism a...
2398
passage: title: Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February abstract: The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. W...
5906
passage: title: Realized Volatility Forecasting with Neural Networks abstract: Abstract In the last few decades, a broad strand of literature in finance has implemented artificial neural networks as a forecasting method. The major advantage of this approach is the possibility to approximate any linear and nonlinear beh...
2343
passage: title: Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials abstract: Evidence on preventing Alzheimer's disease (AD) is challenging to interpret due to varying study designs with heterogeneous endpoi...
2343
passage: decided criteria, from which 104 modifiable factors and 11 interventions were included in the meta-analyses. title: Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials Twenty-one suggestions are pro...
8225
passage: title: Collaboration, Co-Optation or Navigation? The Role of Civil Society in Disaster Governance in India abstract: Abstract Existing research on civil society organizations (CSOs) facing restricted civic space largely focuses on the crackdown on freedoms and CSOs’ strategies to handle these restrictions, oft...
8225
passage: organization-level considerations and actions, and evolving relations, shape who collaborates with whom and to what effect. title: Collaboration, Co-Optation or Navigation? The Role of Civil Society in Disaster Governance in India This article thus stresses interplay and agency, moving away from simple unders...
5506
passage: title: Implication of backward contact tracing in the presence of overdispersed transmission in COVID-19 outbreak abstract: Abstract Unlike forward contact tracing, backward contact tracing identifies the source of newly detected cases. This approach is particularly valuable when there is high individual-level...
6451
passage: title: Army ants dynamically adjust living bridges in response to a cost–benefit trade-off abstract: The ability of individual animals to create functional structures by joining together is rare and confined to the social insects. Army ants (Eciton) form collective assemblages out of their own bodies to perfor...
6451
passage: ates from their incoming direction and move the bridges over time to create shortcuts over large gaps. title: Army ants dynamically adjust living bridges in response to a cost–benefit trade-off The final position of the structure depended on the intensity of the traffic and the extent of path deviation and wa...
2670
passage: title: Words without meaning abstract: Many of the words used by scientists when reviewing manuscripts, job candidates and grant applications – words such as incremental, novelty, mechanism, descriptive and impact – have lost their meaning.
3497
passage: title: Does Stretching Training Influence Muscular Strength? A Systematic Review With Meta-Analysis and Meta-Regression abstract: Abstract Thomas, E, Ficarra, S, Nunes, JP, Paoli, A, Bellafiore, M, Palma, A, and Bianco, A. Does stretching training influence muscular strength? A systematic review with meta-anal...
3497
passage: in this review. title: Does Stretching Training Influence Muscular Strength? A Systematic Review With Meta-Analysis and Meta-Regression The interventions lasted for a mean period of 8 weeks (range, 4–24 weeks), 3–4 days per week, applying approximately 4 sets of stretching of approximately 1-minute duration. ...
3497
passage: -regression revealed a significant negative association with study length (β = −0.100; p = 0.004). title: Does Stretching Training Influence Muscular Strength? A Systematic Review With Meta-Analysis and Meta-Regression Chronic static stretching programs increase dynamic muscular strength to a small magnitude....
1087
passage: title: The structure, function and evolution of a complete human chromosome 8 abstract: Abstract The complete assembly of each human chromosome is essential for understanding human biology and evolution 1,2 . Here we use complementary long-read sequencing technologies to complete the linear assembly of human c...
1087
passage: addition, we confirm the overall organization and methylation pattern of the centromere in a diploid human genome. title: The structure, function and evolution of a complete human chromosome 8 Using a dual long-read sequencing approach, we complete high-quality draft assemblies of the orthologous centromere f...
1819
passage: title: Treatment Emergent Violence To Self And Others; A Literature Review of Neuropsychiatric Adverse Reactions For Antidepressant And Neuroleptic Psychiatric Drugs And General Medications. abstract: This paper reviews the literature linking physical violence, directed towards self or others, to serotonergic ...
1819
passage: and ICD-10.Psychiatric drugs and some general medications have effects that are not always the ones intended. title: Treatment Emergent Violence To Self And Others; A Literature Review of Neuropsychiatric Adverse Reactions For Antidepressant And Neuroleptic Psychiatric Drugs And General Medications. Reactions...
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passage: levels which are associated with neuropsychiatric adverse drug reactions (ADRs), such as akathisia. title: Treatment Emergent Violence To Self And Others; A Literature Review of Neuropsychiatric Adverse Reactions For Antidepressant And Neuroleptic Psychiatric Drugs And General Medications. If not recognised, ...
1819
passage: notable. There is limited information linking psychiatric drug disruption of homeostasis and neurotransmitters with violence. title: Treatment Emergent Violence To Self And Others; A Literature Review of Neuropsychiatric Adverse Reactions For Antidepressant And Neuroleptic Psychiatric Drugs And General Medica...
2308
passage: title: SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study abstract: AbstractObjective To investigate the association between SARS-CoV-2 vaccination and myocarditis or myopericarditis. Design Population based cohort study. Setting Denmark. Participants 4 931 775 individuals...
2308
passage: te hazard ratios adjusted for sex, comorbidities, and other potential confounders. title: SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study Results During follow-up, 269 participants developed myocarditis or myopericarditis, of whom 108 (40%) were 12-39 years old and 196...
2308
passage: 1.9) and 1.5 (1.0 to 2.2) per 100 000 vaccinated individuals within 28 days of vaccination, respectively. title: SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study The adjusted hazard ratio among 12-39 year olds was 1.48 (0.74 to 2.98) and the absolute rate was 1.6 (1.0 t...
2308
passage: 10.2) per 100 000 vaccinated individuals within 28 days of vaccination, respectively. title: SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study The adjusted hazard ratio among 12-39 year olds was 5.24 (2.47 to 11.12) and the absolute rate was 5.7 (3.3 to 9.3) per 100 000 ...
6084
passage: title: Molnupiravir Use and 30-Day Hospitalizations or Death in a Previously Uninfected Nonhospitalized High-risk Population With COVID-19 abstract: Abstract Background Clinical benefit of molnupiravir (MPV) in coronavirus disease 2019 (COVID-19)–infected subpopulations is unclear. Methods We used a matched co...
6084
passage: ], 0.27; 95% confidence interval [CI], −.94 to 1.49). title: Molnupiravir Use and 30-Day Hospitalizations or Death in a Previously Uninfected Nonhospitalized High-risk Population With COVID-19 No benefit was observed among those >60 or ≤60 years old (ARD, 0.27; 95% CI, −1.25 to 1.79 vs ARD, −0.29; 95% ...
3724
passage: title: Pediatric Minimal Change Disease and AKI following the Pfizer-BioNTech COVID-19 Vaccine: causal or incidental correlation? abstract: The global coronavirus 2019 (COVID-19) pandemic required vaccination even in children to reduce infection. We report on the development of acute kidney injury (AKI) and mi...
3724
passage: was 1.3 mg/dL and 24-hour urinary protein excretion was 4 grams with fluid overload. title: Pediatric Minimal Change Disease and AKI following the Pfizer-BioNTech COVID-19 Vaccine: causal or incidental correlation? As kidney function continued to decline over the next days, empirical steroid treatment and ren...
3184
passage: title: Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease abstract: Significance Statement The innate immune system is central to injury and repair in the kidney, but the heterogeneity of myeloid cell subsets behind these processes is unknown. Complementary t...
3184
passage: repairing kidney. title: Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease Background Little is known about the roles of myeloid cell subsets in kidney injury and in the limited ability of the organ to repair itself. Characterizing these cells based only on...
3184
passage: d using transcriptomics revealed marked changes in the proportion and gene expression of renal cell types during injury and repair. title: Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease Conventional flow cytometry markers would not have identified the 12...
6387
passage: title: The role of social circle COVID-19 illness and vaccination experiences in COVID-19 vaccination decisions: an online survey of the United States population abstract: Abstract Background Around the world, policymakers have clearly communicated that COVID-19 vaccination programs need to be accepted by a la...
6387
passage: . Logit regression analyses were carried out to identify factors influencing the likelihood of being vaccinated. title: The role of social circle COVID-19 illness and vaccination experiences in COVID-19 vaccination decisions: an online survey of the United States population Results A total of 2840 participant...
6387
passage: respondents indicated that they knew at least one person who had experienced a severe health problem following COVID-19 vaccination. title: The role of social circle COVID-19 illness and vaccination experiences in COVID-19 vaccination decisions: an online survey of the United States population With these surv...
3728
passage: title: A Survey and Analysis of TLS Interception Mechanisms and Motivations: Exploring how end-to-end TLS is made “end-to-me” for web traffic abstract: TLS is an end-to-end protocol designed to provide confidentiality and integrity guarantees that improve end-user security and privacy. While TLS helps defend a...
3728
passage: We first review the use cases expecting plain HTTP traffic and discuss the extent to which TLS hinders these operations. title: A Survey and Analysis of TLS Interception Mechanisms and Motivations: Exploring how end-to-end TLS is made “end-to-me” for web traffic We retain 19 scenarios where access to unencryp...
2702
passage: title: SARS-CoV-2 RNA levels in Scotland’s wastewater abstract: Abstract Nationwide, wastewater-based monitoring was newly established in Scotland to track the levels of SARS-CoV-2 viral RNA shed into the sewage network, during the COVID-19 pandemic. We present a curated, reference data set produced by this na...
2702
passage: available. The methodology for viral quantification and data analysis is briefly described, with links to detailed protocols online. title: SARS-CoV-2 RNA levels in Scotland’s wastewater These wastewater data are contributing to estimates of disease prevalence and the viral reproduction number (R) in Scotland...
7883
passage: title: Black Lives Matter's Effect on Police Lethal Use-of-Force abstract: How has Black Lives Matter (BLM) influenced police lethal force? An event study design finds census places with early BLM protests experienced a 10% to 15% decrease in police homicides from 2014 through 2019, around 200 fewer deaths. Th...
2930
passage: title: The newly introduced SARS-CoV-2 variant A222V is rapidly spreading in Lazio region, Italy abstract: Abstract A new SARS-CoV-2 clade (GV) characterized by S substitution A222V, first reported from Spain in March, is rapidly spreading across Europe. To establish the A222V variant involvement in the infect...
5988
passage: title: Super high-pressure balloon versus scoring balloon to prepare severely calcified coronary lesions: the ISAR-CALC randomised trial abstract: The comparative efficacy of balloon-based techniques to prepare severely calcified coronary lesions before stenting remains poorly studied.We sought to compare sten...
5988
passage: of the study was stent expansion index as assessed by optical coherence tomography (OCT). title: Super high-pressure balloon versus scoring balloon to prepare severely calcified coronary lesions: the ISAR-CALC randomised trial The key secondary endpoints included angiographic, strategy and procedural success....
5988
passage: =0.02) without difference in terms of angiographic success (100% vs 97.3%; p>0.99). title: Super high-pressure balloon versus scoring balloon to prepare severely calcified coronary lesions: the ISAR-CALC randomised trial Strategy success (91.9% vs 83.8%; p=0.48) and procedural success (100% vs 89.2%; p=0.12) ...
4890
passage: title: The UK government’s covid complacency shows lessons haven’t been learned abstract: This week, England’s health secretary, Sajid Javid told a Downing Street covid briefing that the government would not “at this point” be implementing its so-called “Plan B” measures to prevent the NHS being overwhelmed—in...
6718
passage: title: SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020 abstract: Compared with the volume of data on coronavirus disease 2019 (COVID-19) outbreaks among older adults, relatively few data are available concerning COVID-19 in younger, ...
6718
passage: mild symptoms and asymptomatic infection among this sample of mostly young, healthy adults with close, congregate exposures. title: SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020 Service members who reported taking preventive measu...
5423
passage: title: New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination abstract: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease resulting from the interaction of genetic and environmental factors. In addition, some antiviral vaccines have been associated with the onset of SLE. ...
5423
passage: 4 levels. She was initially treated with low-dose prednisone and hydroxychloroquine. title: New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination Hydroxychloroquine was discontinued after she developed an urticarial rash. Subsequently, mycophenolate mofetil was added after she developed pro...
3213
passage: title: A Sustainable and Global Health Perspective of the Dietary Pattern of French Population during the 1998–2015 Period from INCA Surveys abstract: In France, the evolution of dietary pattern relative to sustainability and global health remains insufficiently studied. The objective of this study was to asse...
3213
passage: the 2015 survey, e.g., fiber, EPA, DHA, magnesium, retinol, and vitamin C. title: A Sustainable and Global Health Perspective of the Dietary Pattern of French Population during the 1998–2015 Period from INCA Surveys In children, UPF daily calories increased from 42.8 to 45.5% and decreased in adults from 39.2...
3017
passage: title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock abstract: Acute myocardial infarction (AMI) complicated by cardioge...
3017
passage: cardiogenic shock is associated with substantial morbidity and mortality. title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogeni...
3017
passage: who were included in data from hospitals participating in the CathPCI and the Chest Pain-MI registries, title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarc...
3017
passage: Data Registry. title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock Patients receiving an intravascular microaxial LVAD...
3017
passage: cardiogenic shock, the mean (SD) age was 65.0 (12.6) years, 67.0% were men, title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardioge...
3017
passage: -elevation myocardial infarction, and 43.3% had cardiac arrest. title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock Ov...
3017
passage: ]; absolute risk difference, 15.4 percentage points [95% CI, 12.5-18.2]; P <.001). title: Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by C...
382
passage: title: Fluvoxamine for outpatients with COVID-19: where do we stand? abstract: Advances in vaccine development have had a major effect on reducing the number of new symptomatic cases, hospitalisations, and deaths due to COVID-19, the viral disease caused by SARS-CoV-2, globally.1Tregoning JS Flight KE Higham S...
382
passage: : what 1.7 billion doses have taught scientists.Nature. title: Fluvoxamine for outpatients with COVID-19: where do we stand? 2021; 594: 164-167Crossref PubMed Scopus (47) Google Scholar Therefore, the identification of beneficial interventions to prevent clinically relevant outcomes among patients with COVID-...
382
passage: phages, and carrageenan-induced paw edema in rat.Iran J Basic Med Sci. title: Fluvoxamine for outpatients with COVID-19: where do we stand? 2016; 19: 977-984PubMed Google Scholar fluvoxamine has been proposed as a potential therapy for COVID-19. Accordingly, observational evidence has suggested favourable res...
382
passage: al deterioration in outpatients with symptomatic COVID-19: a randomized clinical trial.JAMA. title: Fluvoxamine for outpatients with COVID-19: where do we stand? 2020; 324: 2292-2300Crossref PubMed Scopus (344) Google Scholar The primary outcome was clinical deterioration, defined as shortness of breath or ho...
382
passage: precluded definitive conclusions about the efficacy of fluvoxamine for the treatment of COVID-19. title: Fluvoxamine for outpatients with COVID-19: where do we stand? In The Lancet Global Health, Gilmar Reis and colleagues report the results of TOGETHER, a randomised, adaptive, platform, placebo-controlled tr...
382
passage: or matching placebo. title: Fluvoxamine for outpatients with COVID-19: where do we stand? All included participants had a positive test for SARS-CoV-2 and known risk factors for disease progression (including age ≥50 years, diabetes, hypertension, obesity, smoking, conditions associated with immunosuppression...
382
passage: ity of superiority of 99·8%. The TOGETHER trial had low risk of bias. title: Fluvoxamine for outpatients with COVID-19: where do we stand? The allocation was concealed, participants, investigators, and caregivers were unaware of treatment assignments, and the main analyses followed the intention-to-treat prin...
382
passage: the scientific exchange between academic groups from Brazil and Canada and on the use of an adaptive, platform, randomised design. title: Fluvoxamine for outpatients with COVID-19: where do we stand? This research methodology allows simultaneous and efficient assessment of different potential therapies for CO...
382
passage: ity and hospitalisations still need addressing. title: Fluvoxamine for outpatients with COVID-19: where do we stand? In addition, it remains to be established whether fluvoxamine has an additive effect to other therapies such as monoclonal antibodies7Yu L-M Bafadhel M Dorward J et al.Inhaled budesonide for CO...
382
passage: Crossref Scopus (1088) Google Scholar and what is the optimal fluvoxamine therapeutic scheme. title: Fluvoxamine for outpatients with COVID-19: where do we stand? Finally, it is still unclear whether the results from the TOGETHER trial extend to other outpatient populations with COVID-19, including those with...
4237
passage: title: COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance abstract: Abstract Variants of SARS-CoV-2 are evolving under a combination of immune selective pressure in infected hosts and natural genetic drift, raising a global alarm regarding...
4237
passage: = 25 countries, mean correlation coefficient = −0.72, S.D. = 0.20). title: COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance Given that the COVID-19 vaccines leverage B-cell and T-cell epitopes, analysis of mutation rates shows neutraliz...
4237
passage: COVID-associated complications and pre-existing conditions relative to unvaccinated COVID-19 patients. title: COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance This study presents the first known evidence that COVID-19 vaccines are funda...
4721
passage: title: Paleoeconomy more than demography determined prehistoric human impact in Arctic Norway abstract: Population size has increasingly been taken as the driver of past human environmental impact worldwide, and particularly in the Arctic. However, sedimentary ancient DNA (sedaDNA), pollen and archaeological d...
4721
passage: -site lake record of plant and animal sedaDNA. title: Paleoeconomy more than demography determined prehistoric human impact in Arctic Norway The rich animal sedaDNA data (42 taxa) and on-site faunal analyses reveal switches in human dietary composition from early-Holocene fish + marine mammals, to mixed marin...
9547
passage: title: Patrimonialisations de la littérature abstract: Parmi les domaines caractérisés par une charge patrimoniale forte, la littérature continue d’occuper une position de premier plan dans les sociétés contemporaines. Si nous connaissons la littérature du passé et lui accordons une valeur, c’est en effet dans...
9547
passage: d’un savoir historique et l’affectivité spécifique que suscite un passé rendu présent, disponible et légitime. title: Patrimonialisations de la littérature L’une des principales finalités de ce dossier est d’identifier certaines des lignes de force de ce processus multiforme et de contribuer ainsi au dialogue...
9547
passage: establishment of historical knowledge and the particular affectivity elicited by a past made present, available and legitimate. title: Patrimonialisations de la littérature One of the main objectives of this issue is to identify the main thrusts of this multifold process and thus to contribute to the dialogue...
9547
passage: ción del saber histórico y la afectividad específica originada por un pasado que se torna presente, disponible y legítimo. title: Patrimonialisations de la littérature Uno de los principales propósitos de este dossier es identificar algunas de las principales líneas de este proceso multiforme y contribuir así...
9477
passage: title: Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants abstract: ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has led to growing concerns over increased transmissibility and the ability of some variants to partially escape immunity. Sera f...
9477
passage: compared to neutralization of the wild-type SARS-CoV-2 virus (designated as D614G). title: Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants Results showed minimal effects on neutralization titers against the B.1.1.7 (Alpha) variant (1.2-fold reduction compared with D614G); other VOCs such ...
4795
passage: title: Multisystem Inflammatory Syndrome in Children in the United States abstract: 23 issue) present case series of the multisystem inflammatory syndrome in children (MIS-C; also called the pediatric inflammatory multisystem syndrome); Levin 3 provides commentary.To address the burden of MIS-C in France, a na...
4795
passage: ieties.Results in the first 108 cases have been published; similar to the cases reported by Feldstein et al. title: Multisystem Inflammatory Syndrome in Children in the United States and Dufort et al., these results showed a median patient age of 8 years, a temporospatial distribution that is evocative of a l...
4795
passage: respiratory syndrome coronavirus 2 (SARS-CoV-2), according to our case definition (Fig. 1). title: Multisystem Inflammatory Syndrome in Children in the United States 4 A sharp decrease in the incidence of cases occurred 3 to 4 weeks after the decrease in the Covid-19 outbreak in France.These updated surveilla...
4747
passage: title: Low HDL and high triglycerides predict COVID-19 severity abstract: Abstract Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain the association of the plasma lipid profile w...
4747
passage: glyceride concentrations were correlated with ferritin and D-dimer levels but not with CRP levels. title: Low HDL and high triglycerides predict COVID-19 severity The presence of atherogenic dyslipidaemia during the infection was strongly and independently associated with a worse COVID-19 infection prognosis....
9366
passage: title: David Oliver: “Considerably transformed”—changing the narrative on admitting older patients abstract: Considerably transformed"-changing the narrative on admitting older patients
5334
passage: title: SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors abstract: Virus entry into animal cells is initiated by attachment to target macromolecules located on host cells. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) trimeric spike glycoprotein targets host angiotensi...
5334
passage: (nAChR) subtypes via this region. title: SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors Using a peptide of the neurotoxin-like region of SARS-CoV-2 (SARS-CoV-2 glycoprotein peptide [SCoV2P]), we identified that this area moderately inhibits α3β2, α3β4, and α4β2 subtypes, while potent...
5334
passage: in transfected neuronal-like N2a and human embryonic kidney 293 cells. title: SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors The SARS-CoV-2 ectodomain functionally potentiates and inhibits the α7 subtype with nanomolar potency. Our functional findings identify that the α7 nAChR is a ...
6652
passage: title: The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters abstract: Abstract The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19 pandemic. End of November 2021, a new SARS-CoV-2 variant namely the omicron (B.1.1.529) emerged. Since this...
6652
passage: s as compared to animals infected with D614G and no infectious virus was detectable in this organ. title: The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters Moreover, histopathological examination of the lungs from omicron-infecetd hamsters revealed no signs of peri-...
9032
passage: title: SARS-CoV-2 Vaccination and Protection Against Clinical Disease: A Retrospective Study, Bouches-du-Rhône District, Southern France, 2021 abstract: From January 18th to August 13th, 2021, 13,804 unvaccinated and 1,156 patients who had received at least one COVID-19 vaccine dose were tested qPCR-positive f...
9032
passage: 6, of the Alpha/20I variant from weeks 7 to 25, and of the Delta/21A variant from week 26. title: SARS-CoV-2 Vaccination and Protection Against Clinical Disease: A Retrospective Study, Bouches-du-Rhône District, Southern France, 2021 SARS-CoV-2 infection was significantly more likely to occur in the first 13 ...
9032
passage: breakpoint at 54, 33, and 53 years for death, transfer to ICU, and hospitalization, respectively. title: SARS-CoV-2 Vaccination and Protection Against Clinical Disease: A Retrospective Study, Bouches-du-Rhône District, Southern France, 2021 Among patients infected by the Delta/21A or Alpha/20I variants, parti...
580
passage: title: A Meta-Analysis of the Impacts of Genetically Modified Crops abstract: Background Despite the rapid adoption of genetically modified (GM) crops by farmers in many countries, controversies about this technology continue. Uncertainty about GM crop impacts is one reason for widespread public suspicion. Obj...
580
passage: Synthesis Methods Analysis of mean impacts and meta-regressions to examine factors that influence outcomes. title: A Meta-Analysis of the Impacts of Genetically Modified Crops Results On average, GM technology adoption has reduced chemical pesticide use by 37%, increased crop yields by 22%, and increased farm...
9491
passage: title: Change in Antibodies to SARS-CoV-2 Over 60 Days Among Health Care Personnel in Nashville, Tennessee abstract: Hui Zeng, MD; Chen Xu, BS; Junli Fan, MD; Yueting Tang, PhD; Qiaoling Deng, MD; Wei Zhang, MD, PhD; Xinghua Long, MD, PhD
6526
passage: title: Association of Logic’s hip hop song “1-800-273-8255” with Lifeline calls and suicides in the United States: interrupted time series analysis abstract: Abstract Objective To assess changes in daily call volumes to the US National Suicide Prevention Lifeline and in suicides during periods of wide scale pu...
6526
passage: Models were fitted to the full time series with dummy variables for periods of strong attention to the song. title: Association of Logic’s hip hop song “1-800-273-8255” with Lifeline calls and suicides in the United States: interrupted time series analysis Results In the 34 day period after the three events w...
4346
passage: title: Skill utilization at work: Opportunity and motivation abstract: Technological choices, product market strategies, and other organizational characteristics affect how tasks are grouped into jobs.The design of jobs determines the skills needed by workers in order to do them effectively.However, people pos...
4346
passage: , which leads to huge variation in job design and complexity.Complex jobs pose a challenge for management and workers; title: Skill utilization at work: Opportunity and motivation an incentive structure aimed at unlocking workers' potential can effectively address this challenge.However, the heterogeneity of ...