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id
int64
age_years
int64
sex
string
education
string
socioeconomic_status
string
overcrowded_housing
int64
hiv_positive
int64
detection_mode
string
whf_category
string
history_arf
int64
arf_episodes
int64
age_at_first_arf
int64
sore_throat_history
int64
mitral_valve_disease
int64
aortic_valve_disease
int64
tricuspid_valve_disease
int64
mitral_lesion
string
aortic_lesion
string
valve_severity
string
multivalve
int64
nyha_class
int64
atrial_fibrillation
int64
lvef_percent
int64
lv_dysfunction
int64
pulmonary_hypertension
int64
congestive_heart_failure
int64
stroke
int64
infective_endocarditis
int64
recurrent_arf
int64
on_penicillin_prophylaxis
int64
penicillin_adherence
string
on_diuretics
int64
on_ace_inhibitor
int64
on_beta_blocker
int64
on_digoxin
int64
on_anticoagulation
int64
anticoagulation_type
string
inr_in_range
int64
valve_surgery
int64
surgery_type
string
referred_for_surgery
int64
outcome_2yr
string
functional_status_2yr
string
1
34
F
secondary
low
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
mixed
none
mild
0
1
0
50
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
2
48
F
primary
low
1
0
echo_screening
borderline
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
1
63
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
3
34
M
none
middle
0
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
stenosis
moderate
1
3
0
57
0
0
1
0
0
0
0
not_applicable
1
0
0
1
0
none
0
0
none
0
died
unknown
4
16
M
secondary
middle
0
0
clinical_presentation
definite
0
0
-1
1
1
1
0
regurgitation
regurgitation
moderate
1
1
0
56
0
0
1
0
0
0
1
good
1
0
0
0
0
none
0
0
none
0
alive
moderate
5
22
F
secondary
low
1
0
echo_screening
borderline
0
0
-1
1
1
0
0
mixed
none
moderate
0
3
0
50
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
died
unknown
6
24
M
none
low
0
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
mixed
mild
1
1
0
61
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
7
17
F
tertiary
low
0
0
echo_screening
borderline
0
0
-1
0
1
0
1
mixed
none
mild
1
1
0
75
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
8
15
M
tertiary
low
1
0
echo_screening
definite
0
0
-1
0
1
0
0
mixed
none
severe
0
3
1
58
0
1
0
0
0
0
0
not_applicable
0
0
1
1
0
none
0
0
none
0
died
unknown
9
24
F
secondary
low
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
severe
0
4
0
40
1
1
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
poor
10
22
F
none
middle
0
0
clinical_presentation
definite
1
6
16
0
1
1
0
stenosis
mixed
severe
1
3
1
53
0
0
0
0
0
0
0
not_applicable
0
0
0
1
1
warfarin
1
0
none
0
died
unknown
11
14
M
primary
low
1
1
clinical_presentation
definite
1
1
13
0
1
0
0
mixed
none
severe
0
1
1
73
0
1
1
0
0
0
0
not_applicable
1
0
1
0
1
aspirin
0
0
none
0
alive
moderate
12
58
F
secondary
middle
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
2
1
34
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
13
49
F
secondary
middle
1
0
clinical_presentation
definite
0
0
-1
0
1
0
1
mixed
none
mild
1
3
1
48
1
0
0
0
0
0
0
not_applicable
0
0
0
1
0
none
0
0
none
0
died
unknown
14
34
M
secondary
middle
0
0
echo_screening
definite
0
0
-1
1
1
1
1
regurgitation
stenosis
moderate
1
3
0
60
0
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
died
unknown
15
5
F
primary
middle
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
3
1
66
0
0
0
1
0
0
0
not_applicable
0
0
1
0
0
none
0
0
none
0
alive
moderate
16
58
F
none
high
0
0
echo_screening
borderline
0
0
-1
0
1
0
1
mixed
none
mild
1
1
1
59
0
0
1
0
0
0
1
good
1
0
0
1
0
none
0
0
none
0
died
unknown
17
59
F
secondary
middle
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
mixed
none
mild
0
1
0
71
0
0
0
0
0
0
1
poor
0
0
0
0
0
none
0
0
none
0
alive
good
18
14
M
primary
high
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
stenosis
none
mild
0
3
1
56
0
0
0
0
0
0
1
good
0
0
1
0
0
none
0
0
none
0
alive
moderate
19
16
M
secondary
low
1
0
clinical_presentation
definite
1
4
14
0
1
0
0
regurgitation
none
moderate
0
3
0
55
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
moderate
20
9
M
secondary
low
1
0
clinical_presentation
definite
1
1
4
0
1
1
0
regurgitation
regurgitation
severe
1
4
0
33
1
0
0
0
0
1
1
moderate
0
0
0
0
0
none
0
0
none
0
died
unknown
21
58
F
secondary
high
1
0
clinical_presentation
definite
1
3
8
0
1
1
0
regurgitation
stenosis
moderate
1
1
1
41
1
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
22
39
F
secondary
high
0
0
clinical_presentation
definite
0
0
-1
1
1
0
0
stenosis
none
mild
0
1
1
56
0
0
0
0
0
0
0
not_applicable
0
0
1
1
0
none
0
0
none
0
alive
good
23
56
F
secondary
high
0
0
echo_screening
definite
1
3
18
0
1
0
0
regurgitation
none
mild
0
1
0
53
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
24
34
F
tertiary
middle
1
0
clinical_presentation
definite
1
6
9
0
1
1
0
stenosis
regurgitation
moderate
1
3
0
39
1
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
moderate
25
20
M
none
low
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
mixed
none
mild
0
1
0
72
0
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
died
unknown
26
23
F
secondary
middle
1
0
clinical_presentation
definite
1
5
6
1
1
0
0
stenosis
none
severe
0
4
1
47
1
0
0
0
0
0
1
moderate
0
0
1
0
0
none
0
0
none
0
alive
poor
27
14
M
none
low
1
0
clinical_presentation
definite
1
1
7
1
1
0
0
regurgitation
none
moderate
0
2
1
57
0
0
0
1
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
28
14
F
secondary
low
1
0
clinical_presentation
definite
0
0
-1
0
1
1
1
mixed
regurgitation
mild
1
1
1
40
1
0
1
0
0
0
0
not_applicable
1
0
0
1
0
none
0
0
none
0
alive
moderate
29
17
F
secondary
high
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
1
53
0
0
0
0
0
0
1
poor
0
0
0
1
1
aspirin
0
0
none
0
alive
good
30
24
F
none
low
0
0
clinical_presentation
definite
0
0
-1
0
1
0
0
regurgitation
none
moderate
0
2
0
32
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
31
32
F
secondary
high
1
0
clinical_presentation
definite
0
0
-1
1
1
1
0
regurgitation
stenosis
mild
1
3
1
69
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
moderate
32
35
F
secondary
middle
1
0
echo_screening
definite
1
2
19
1
1
0
0
regurgitation
none
severe
0
3
1
51
0
0
1
0
0
0
1
good
1
1
0
1
1
aspirin
0
0
none
0
died
unknown
33
14
F
primary
low
1
0
echo_screening
borderline
0
0
-1
1
1
1
0
mixed
mixed
moderate
1
4
0
38
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
poor
34
6
M
primary
high
0
0
clinical_presentation
definite
1
3
5
1
1
1
0
mixed
regurgitation
moderate
1
2
1
59
0
0
0
0
0
0
1
good
0
0
1
0
0
none
0
0
none
0
alive
good
35
17
F
secondary
low
1
0
echo_screening
borderline
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
0
65
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
36
49
F
secondary
low
1
0
clinical_presentation
definite
1
3
13
1
1
0
0
regurgitation
none
severe
0
3
1
51
0
1
1
0
0
0
1
poor
1
0
0
0
0
none
0
0
none
0
died
unknown
37
39
M
primary
high
0
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
3
0
51
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
moderate
38
13
M
secondary
middle
0
1
clinical_presentation
definite
1
3
12
1
1
1
0
mixed
regurgitation
moderate
1
3
0
28
1
0
1
0
0
0
1
poor
1
0
0
0
0
none
0
0
none
0
alive
moderate
39
16
F
primary
middle
0
0
clinical_presentation
definite
1
8
15
0
1
1
0
regurgitation
regurgitation
severe
1
4
1
39
1
0
0
0
0
0
1
moderate
0
0
0
1
0
none
0
0
none
0
died
unknown
40
58
F
none
low
0
0
echo_screening
borderline
0
0
-1
1
1
1
0
stenosis
stenosis
mild
1
2
0
67
0
0
1
0
0
0
0
not_applicable
1
0
0
1
0
none
0
0
none
0
alive
moderate
41
18
F
secondary
low
1
0
echo_screening
borderline
0
0
-1
0
1
0
1
regurgitation
none
mild
1
1
1
58
0
0
0
0
0
0
0
not_applicable
0
0
0
1
1
aspirin
0
0
none
0
alive
good
42
22
F
none
low
0
0
echo_screening
borderline
0
0
-1
0
1
0
0
regurgitation
none
moderate
0
1
1
46
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
43
49
M
secondary
low
0
0
echo_screening
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
3
0
42
1
0
1
0
0
0
1
moderate
1
1
0
1
0
none
0
0
none
0
died
unknown
44
43
F
primary
high
0
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
regurgitation
mild
1
1
1
57
0
0
0
0
0
0
1
moderate
0
0
1
0
0
none
0
0
none
0
alive
good
45
53
M
none
middle
1
0
echo_screening
definite
0
0
-1
0
1
0
0
mixed
none
moderate
0
3
1
38
1
0
1
0
0
0
1
moderate
1
1
1
1
1
aspirin
0
0
none
0
died
unknown
46
15
F
primary
middle
0
0
clinical_presentation
definite
1
2
13
1
1
0
0
regurgitation
none
mild
0
2
0
64
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
47
39
F
primary
high
0
1
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
1
0
36
1
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
good
48
15
F
tertiary
high
0
0
echo_screening
definite
1
1
14
1
1
0
0
regurgitation
none
moderate
0
2
1
58
0
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
49
22
M
primary
middle
1
0
clinical_presentation
definite
1
1
15
1
1
0
1
stenosis
none
severe
1
3
1
45
1
1
1
0
0
1
0
not_applicable
1
0
1
0
0
none
0
0
none
1
died
unknown
50
52
M
secondary
high
0
0
clinical_presentation
definite
1
2
13
0
1
0
0
mixed
none
severe
0
4
0
39
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
died
unknown
51
12
F
primary
high
0
1
clinical_presentation
definite
1
2
11
0
1
1
0
regurgitation
regurgitation
moderate
1
4
0
49
1
0
1
0
0
0
0
not_applicable
1
1
0
1
0
none
0
0
none
0
alive
poor
52
41
F
secondary
middle
1
0
echo_screening
borderline
0
0
-1
1
1
0
0
mixed
none
mild
0
1
0
59
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
53
24
F
primary
middle
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
mixed
none
moderate
0
3
0
50
0
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
54
26
F
primary
middle
1
0
echo_screening
borderline
0
0
-1
0
1
1
0
regurgitation
regurgitation
mild
1
1
0
60
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
55
17
M
secondary
middle
1
0
echo_screening
borderline
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
0
41
1
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
56
18
M
secondary
high
0
0
echo_screening
definite
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
0
62
0
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
good
57
55
F
tertiary
low
1
0
echo_screening
definite
1
2
5
1
1
0
0
stenosis
none
mild
0
1
0
56
0
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
good
58
24
F
primary
low
0
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
2
0
42
1
0
1
0
0
0
1
good
1
0
0
0
0
none
0
0
none
0
alive
moderate
59
27
F
primary
high
1
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
mixed
moderate
1
3
0
47
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
died
unknown
60
14
F
secondary
low
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
mixed
none
mild
0
2
0
43
1
0
1
0
0
0
0
not_applicable
0
0
0
1
0
none
0
0
none
0
died
unknown
61
8
F
secondary
low
0
0
clinical_presentation
definite
0
0
-1
0
1
1
0
mixed
mixed
severe
1
4
1
38
1
1
0
0
0
0
0
not_applicable
0
0
1
0
0
none
0
0
none
0
alive
poor
62
20
F
primary
middle
0
0
clinical_presentation
definite
1
3
14
0
1
0
0
regurgitation
none
severe
0
3
0
33
1
1
1
0
0
0
1
poor
0
0
0
0
0
none
0
0
none
0
died
unknown
63
15
M
tertiary
middle
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
1
73
0
0
1
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
moderate
64
21
F
primary
low
0
0
clinical_presentation
definite
1
4
13
1
1
0
0
regurgitation
none
moderate
0
2
0
67
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
65
12
F
none
low
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
stenosis
none
severe
0
3
0
26
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
died
unknown
66
9
M
none
low
0
0
clinical_presentation
definite
0
0
-1
1
1
1
0
regurgitation
stenosis
moderate
1
3
1
54
0
0
0
0
0
0
0
not_applicable
0
0
1
1
0
none
0
0
none
0
died
unknown
67
36
F
secondary
middle
0
0
clinical_presentation
definite
0
0
-1
0
1
0
0
mixed
none
severe
0
4
1
26
1
0
1
0
0
0
0
not_applicable
0
1
1
1
0
none
0
0
none
0
died
unknown
68
14
F
secondary
low
1
0
echo_screening
borderline
0
0
-1
1
1
0
1
mixed
none
mild
1
2
0
49
1
0
1
0
0
0
1
good
0
0
0
1
0
none
0
0
none
0
alive
moderate
69
27
F
tertiary
low
1
0
clinical_presentation
definite
1
1
17
0
1
0
0
stenosis
none
severe
0
4
0
52
0
1
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
died
unknown
70
54
F
primary
high
1
0
echo_screening
borderline
0
0
-1
0
1
0
0
stenosis
none
mild
0
2
0
35
1
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
71
20
F
secondary
low
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
mixed
none
moderate
0
3
0
50
0
0
0
0
0
0
1
poor
0
0
0
0
0
none
0
0
none
0
alive
moderate
72
8
F
secondary
low
1
0
clinical_presentation
definite
0
0
-1
1
1
0
1
mixed
none
moderate
1
1
1
42
1
0
1
0
0
0
0
not_applicable
1
0
1
1
0
none
0
0
none
0
alive
moderate
73
36
M
primary
low
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
mild
0
2
0
59
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
74
42
F
none
low
0
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
severe
0
3
1
41
1
0
1
0
0
0
0
not_applicable
0
1
0
0
0
none
0
0
none
0
alive
moderate
75
18
F
primary
low
1
0
clinical_presentation
definite
0
0
-1
1
1
1
0
regurgitation
mixed
moderate
1
2
0
56
0
0
1
0
0
0
1
moderate
1
1
0
0
0
none
0
0
none
0
died
unknown
76
50
F
secondary
middle
0
0
clinical_presentation
definite
1
2
15
1
1
1
1
regurgitation
regurgitation
moderate
1
1
1
37
1
0
1
0
0
0
1
good
1
0
0
0
0
none
0
0
none
0
alive
moderate
77
15
F
secondary
high
1
0
echo_screening
borderline
0
0
-1
0
1
0
0
regurgitation
none
mild
0
1
0
53
0
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
78
12
F
primary
low
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
regurgitation
none
moderate
0
1
0
44
1
0
1
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
died
unknown
79
20
F
secondary
low
0
0
echo_screening
borderline
0
0
-1
1
1
0
1
regurgitation
none
mild
1
2
1
49
1
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
died
unknown
80
43
F
tertiary
low
0
0
clinical_presentation
definite
0
0
-1
0
1
0
0
regurgitation
none
mild
0
2
1
61
0
0
1
1
0
0
1
poor
1
0
0
0
1
warfarin
0
0
none
0
alive
moderate
81
23
F
primary
low
1
0
echo_screening
borderline
0
0
-1
1
1
0
0
stenosis
none
moderate
0
2
0
54
0
0
1
0
0
0
0
not_applicable
1
1
0
0
0
none
0
0
none
0
died
unknown
82
25
F
secondary
high
0
0
echo_screening
definite
0
0
-1
1
1
1
0
stenosis
regurgitation
mild
1
1
0
50
0
0
1
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
moderate
83
21
F
none
low
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
regurgitation
none
mild
0
2
0
51
0
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
84
5
M
primary
low
1
0
clinical_presentation
definite
1
3
4
1
1
0
0
regurgitation
none
moderate
0
1
1
61
0
0
0
0
0
0
0
not_applicable
0
0
0
1
1
warfarin
0
0
none
0
died
unknown
85
22
F
primary
middle
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
regurgitation
none
mild
0
1
0
61
0
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
died
unknown
86
31
F
primary
low
1
1
echo_screening
definite
1
1
17
0
1
1
0
mixed
regurgitation
mild
1
1
0
63
0
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
87
20
F
tertiary
low
0
0
clinical_presentation
definite
1
1
15
1
1
0
1
mixed
none
severe
1
2
0
40
1
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
88
38
F
secondary
high
1
0
clinical_presentation
definite
0
0
-1
1
1
0
0
stenosis
none
severe
0
4
0
31
1
0
1
0
0
0
1
moderate
0
0
0
1
0
none
0
0
none
0
died
unknown
89
38
F
secondary
low
1
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
mixed
mild
1
1
1
66
0
0
0
0
0
0
0
not_applicable
0
0
1
0
0
none
0
0
none
0
alive
good
90
13
F
tertiary
middle
0
0
echo_screening
borderline
0
0
-1
1
1
0
0
regurgitation
none
mild
0
3
0
54
0
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
moderate
91
47
M
secondary
low
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
mixed
none
severe
0
3
0
49
1
1
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
moderate
92
16
M
primary
middle
1
0
clinical_presentation
definite
1
2
11
0
1
0
1
regurgitation
none
moderate
1
1
0
59
0
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
good
93
47
F
secondary
middle
0
0
echo_screening
definite
1
1
4
1
1
1
0
regurgitation
regurgitation
moderate
1
2
0
51
0
0
0
0
0
0
1
moderate
0
0
0
0
0
none
0
0
none
0
alive
good
94
40
F
secondary
low
0
1
clinical_presentation
definite
0
0
-1
1
1
0
0
mixed
none
moderate
0
3
0
29
1
0
1
0
0
0
0
not_applicable
0
0
0
1
0
none
0
0
none
0
alive
moderate
95
27
F
primary
low
1
0
clinical_presentation
definite
0
0
-1
0
1
0
0
regurgitation
none
severe
0
2
0
38
1
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
alive
good
96
48
F
primary
middle
0
0
echo_screening
borderline
0
0
-1
1
1
1
0
regurgitation
regurgitation
mild
1
1
0
56
0
0
1
0
0
0
0
not_applicable
1
1
0
0
0
none
0
0
none
0
alive
moderate
97
16
F
secondary
low
0
0
clinical_presentation
definite
0
0
-1
1
1
1
0
regurgitation
stenosis
severe
1
3
0
53
0
0
1
0
0
0
1
poor
1
0
0
0
0
none
0
0
none
0
alive
moderate
98
19
F
primary
low
0
0
clinical_presentation
definite
1
1
8
1
1
1
0
regurgitation
mixed
moderate
1
2
1
35
1
0
0
0
0
0
1
good
0
0
0
0
0
none
0
0
none
0
alive
good
99
5
F
secondary
low
0
0
echo_screening
borderline
0
0
-1
0
1
1
0
regurgitation
regurgitation
moderate
1
3
1
49
1
0
0
0
0
0
0
not_applicable
0
0
0
0
0
none
0
0
none
0
died
unknown
100
20
M
tertiary
low
0
0
echo_screening
borderline
0
0
-1
0
1
1
0
regurgitation
stenosis
mild
1
1
1
66
0
0
1
0
0
0
0
not_applicable
1
0
0
0
0
none
0
0
none
0
alive
moderate
End of preview. Expand in Data Studio

Rheumatic Heart Disease Dataset

Abstract

This dataset provides 30,000 simulated records (10,000 per scenario) of patients aged 5–60 years with rheumatic heart disease across sub-Saharan African settings. Each record contains 45+ variables including WHF classification, valve involvement, severity, NYHA class, LVEF, atrial fibrillation, complications (CHF, stroke, IE), penicillin prophylaxis adherence, valve surgery, and 2-year outcomes. Three settings: cardiac referral centre (18.4% 2-year mortality), district hospital (32.0%), and community screening programme (5.4%).

1. Introduction

RHD affects 40.5 million people globally with 306,000 deaths/year, 80% in LMICs (Watkins et al., NEJM 2017). The REMEDY study of 3,343 patients across 14 LMICs found a 2-year case fatality of 16.9% despite a median age of only 28 years (Zuhlke et al., Circulation 2016). Independent predictors of death included severe valve disease (HR 2.36), CHF (HR 2.16), NYHA III/IV (HR 1.67), and atrial fibrillation (HR 1.40). Penicillin prophylaxis adherence was only 55%. Echo screening in Malawi found latent RHD prevalence of 3.4% in schoolchildren (Sims Sanyahumbi et al., 2016).

This dataset is entirely simulated. It must not be used for clinical decision-making.

2. Methodology

2.1 Parameterization

Parameter Value Source
Global RHD burden 40.5M, 306K deaths/yr Watkins et al., NEJM 2017
2-year case fatality (LMICs) 16.9% REMEDY, Zuhlke et al., Circulation 2016
Median age at death 28.7 years REMEDY 2016
Female proportion 66% REMEDY 2016
Mitral valve involvement 97% REMEDY baseline, Zuhlke et al. 2015
Penicillin adherence 55% REMEDY 2016
Latent RHD prevalence (schools) 3.4% Sims Sanyahumbi et al., 2016

2.2 Scenario Design

Scenario Setting Surgery Penicillin CHF 2-Year Mortality
Referral centre Cardiac centre Yes 53% 42% 18.4%
District hospital Basic echo, no surgery No 34% 50% 32.0%
Community screening Screening programme No 17% 10% 5.4%

3. Schema

Column Type Description
id int Unique identifier
age_years int Patient age
sex categorical M / F
education categorical none / primary / secondary / tertiary
socioeconomic_status categorical low / middle / high
overcrowded_housing binary Overcrowded housing
hiv_positive binary HIV status
detection_mode categorical clinical_presentation / echo_screening
whf_category categorical borderline / definite
history_arf binary History of acute rheumatic fever
arf_episodes int Number of ARF episodes
age_at_first_arf int Age at first ARF (-1 if none)
sore_throat_history binary Recurrent sore throat history
mitral_valve_disease binary Mitral valve involvement
aortic_valve_disease binary Aortic valve involvement
tricuspid_valve_disease binary Tricuspid valve involvement
mitral_lesion categorical regurgitation / stenosis / mixed / none
aortic_lesion categorical regurgitation / stenosis / mixed / none
valve_severity categorical mild / moderate / severe
multivalve binary Multi-valve involvement
nyha_class int NYHA functional class (1–4)
atrial_fibrillation binary Atrial fibrillation
lvef_percent int Left ventricular ejection fraction
lv_dysfunction binary LVEF <50%
pulmonary_hypertension binary Pulmonary hypertension
congestive_heart_failure binary CHF
stroke binary Stroke/TIA
infective_endocarditis binary Infective endocarditis
recurrent_arf binary Recurrent ARF during follow-up
on_penicillin_prophylaxis binary On penicillin prophylaxis
penicillin_adherence categorical good / moderate / poor / not_applicable
on_diuretics binary On diuretics
on_ace_inhibitor binary On ACE inhibitor
on_beta_blocker binary On beta blocker
on_digoxin binary On digoxin
on_anticoagulation binary On anticoagulation
anticoagulation_type categorical warfarin / aspirin / none
inr_in_range binary INR therapeutic (warfarin)
valve_surgery binary Valve surgery performed
surgery_type categorical mechanical / bioprosthetic / repair / balloon
referred_for_surgery binary Referred for surgery (no local access)
outcome_2yr categorical alive / died
functional_status_2yr categorical good / moderate / poor / unknown

4. Validation

Validation Report

Key validation checks:

  • 2-year mortality: Referral 18.4%, District 32.0%, consistent with REMEDY 16.9% ✓
  • Female predominance: 66%, matching REMEDY ✓
  • Mitral valve: 97%+ involvement ✓
  • NYHA dose-response: Mortality increases steeply NYHA I→IV ✓
  • Penicillin adherence: 53% referral → 17% community ✓
  • CHF most common complication: 42–50% in clinical settings ✓

5. Usage

from datasets import load_dataset
dataset = load_dataset("electricsheepafrica/rheumatic-heart-disease", "district_hospital")
df = dataset["train"].to_pandas()
python generate_dataset.py --all-scenarios --n 10000 --seed 42

6. Limitations

  • Simulated: Not derived from real RHD registries.
  • No echo images: Valve disease is categorical, not imaged.
  • No Jones criteria: ARF diagnosis is binary, not by Jones criteria components.
  • Simplified surgery: No post-surgical follow-up or prosthetic valve complications.
  • No GAS culture: No throat culture or ASO titre data.

7. References

  1. Zuhlke L, et al. (2016). REMEDY study 2-year follow-up. Circulation, 134(23):1456–1466.
  2. Sims Sanyahumbi A, et al. (2016). RHD screening Malawi. Congenit Heart Dis, 11(6):615–621.
  3. WHF (2023). Echocardiographic criteria for RHD diagnosis update.
  4. Rwebembera J, et al. (2022). Latent RHD SSA. Lancet Glob Health, 10(2):e250.
  5. Watkins D, et al. (2017). Global burden of RHD. NEJM, 377(8):713–722.
  6. Carapetis JR, et al. (2005). GAS → ARF → RHD cascade. Lancet Infect Dis, 5(11):685–694.
  7. Beaton A, et al. (2012). Echo screening Uganda. Circulation, 125(25):3127–3132.
  8. Zuhlke L, et al. (2015). REMEDY baseline. BMC Cardiovasc Disord, 15:134.

Citation

@dataset{esa_rhd_2025,
  title={Rheumatic Heart Disease Dataset},
  author={Electric Sheep Africa},
  year={2025},
  publisher={Hugging Face},
  url={https://huggingface.co/datasets/electricsheepafrica/rheumatic-heart-disease}
}

License

CC-BY-4.0

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