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9,972,040
null
null
Similarities and interactions between GABAergic and glutaminergic systems.
Harmonious interactions between neurotransmitter systems are important for regulating the activity in the central nervous system (CNS). gamma-Aminobutyric acid (GABA) and glutamate (Glu) are major inhibitory and excitatory neurotransmitters in the mammalian central nervous system. Neuronal excitability, probably synapt...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
5-26
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "H Car", "last_name": "Car", "fore_name": "H", "initials": "H", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [], "valid": true, "equal_contrib": null }, { "display_name": "K Wiśniewski", "last_name": "Wiśniewski", "...
[ "Editorial", "Review" ]
[ "eng" ]
[ "Animals", "Central Nervous System", "Electrophysiology", "Glutamic Acid", "Humans", "Sensitivity and Specificity", "gamma-Aminobutyric Acid" ]
[ "Central Nervous System/physiology", "Glutamic Acid/biosynthesis", "gamma-Aminobutyric Acid/biosynthesis" ]
[]
[ "pubmed:9972040" ]
9,972,041
null
null
Histological diagnosis of gastritis based on Sydney System.
The review of literature concerning gastritis, especially the chronic form has been carried out. Based on published data and own authors experience an application of the Sydney System in differential diagnosis of gastritis was presented.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
27-38
1999-03-05
2005-11-16
MEDLINE
ppublish
Print
null
[ { "display_name": "M Barwijuk-Machała", "last_name": "Barwijuk-Machała", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, ...
[ "Journal Article", "Review" ]
[ "eng" ]
[ "Biopsy, Needle", "Chronic Disease", "Female", "Gastritis", "Gastroscopy", "Humans", "Male", "Sensitivity and Specificity" ]
[ "Gastritis/pathology" ]
[]
[ "pubmed:9972041" ]
9,972,042
null
null
Cellular serine carboxypeptidases.
The literature on serine carboxypeptidases of cells is reviewed. These proteases occur in the vacuoles of fungi and higher plants and in the lysosomes of animals and man cells. Physico-chemical properties, chemical structure, catalytic mechanism and substrate specificity of these enzymes are presented.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
39-55
1999-03-05
2012-07-10
MEDLINE
ppublish
Print
null
[ { "display_name": "H Ostrowska", "last_name": "Ostrowska", "fore_name": "H", "initials": "H", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Instrumental Analysis, Medical Academy of Białystok." ], "valid": true, "equal_cont...
[ "Journal Article", "Review" ]
[ "eng" ]
[ "Animals", "Carboxypeptidases", "Cells", "Humans", "Molecular Structure", "Sensitivity and Specificity" ]
[ "Carboxypeptidases/metabolism", "Cells/enzymology" ]
[]
[ "pubmed:9972042" ]
9,972,043
null
null
The effect of cyclophosphamide on the ultrastructure of erythrocytes.
The aim of the present study was to analyse the effect of single intraperitoneal administration of cyclophosphamide (150 mg/kg b.w.) on the morphological changes in erythrocytes. The study of erythrocytes was based on the ultrastructural analysis in the transmission electron microscope (TEM)--in situ examinations and u...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
56-65
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "S Sulkowski", "last_name": "Sulkowski", "fore_name": "S", "initials": "S", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal_contr...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Animals", "Cell Culture Techniques", "Cyclophosphamide", "Disease Models, Animal", "Erythrocytes", "Injections, Intraperitoneal", "Male", "Microscopy, Electron", "Microscopy, Electron, Scanning Transmission", "Rats", "Rats, Wistar", "Reference Values" ]
[ "Cyclophosphamide/pharmacology", "Erythrocytes/drug effects", "Erythrocytes/ultrastructure" ]
[]
[ "pubmed:9972043" ]
9,972,044
null
null
Hyphomycetes in rain water draining from intact trees.
The authors investigated Hyphomycetes in rain water flowing down from leaves of 10 gymnospermous and 10 angiospermous tree species in northeastern Poland. The presence of 57 Hyphomycetes species was noted. Only 17 species were found to develop both on gymnospermous and angiospermous tree species out of 57 found in rain...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
66-84
1999-03-05
2000-12-18
MEDLINE
ppublish
Print
null
[ { "display_name": "B Czeczuga", "last_name": "Czeczuga", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of General Biology, Medical Academy of Białystok." ], "valid": true, "equal_contrib": nu...
[ "Journal Article" ]
[ "eng" ]
[ "Fresh Water", "Fungi", "Mitosporic Fungi", "Poland", "Rain", "Species Specificity", "Trees", "Water Microbiology" ]
[ "Fresh Water/microbiology", "Mitosporic Fungi/isolation & purification", "Rain", "Water Microbiology" ]
[]
[ "pubmed:9972044" ]
9,972,045
null
null
Hyphomycetes in the snow from gymnosperm trees.
The presence of 26 hyphomycete species was noted in snow water collected from coniferous trees. Camposporium pellucidum, Monodictys peruviana, Polystratorictus fusarioideus, Sporidesmium moniliforme, Tripospermum acerinum and Veronaea botryosa were recorded for the first time to Poland. Among the 26 species found in sn...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
85-94
1999-03-05
2000-12-18
MEDLINE
ppublish
Print
null
[ { "display_name": "B Czeczuga", "last_name": "Czeczuga", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of General Biology, Medical Academy of Białystok." ], "valid": true, "equal_contrib": nu...
[ "Journal Article" ]
[ "eng" ]
[ "Fresh Water", "Mitosporic Fungi", "Poland", "Snow", "Species Specificity", "Trees", "Water Microbiology" ]
[ "Fresh Water/microbiology", "Mitosporic Fungi/classification", "Snow", "Water Microbiology" ]
[]
[ "pubmed:9972045" ]
9,972,046
null
null
Effects of Venoruton on early postradiation damage in the lungs of rats.
The study aimed at testing the effects of Venoruton on the early postradiation damage in the lungs of rats. The chests of the rats were irradiated with Co-60, fractional dose 250 cGy/DD, total dose 2500 cGy/DD. Venoruton was given intraperitoneally, in quantities of 0.1 ml once daily for 90 days. The experiment have pr...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
95-109
1999-03-05
2012-11-15
MEDLINE
ppublish
Print
null
[ { "display_name": "E Starosławska", "last_name": "Starosławska", "fore_name": "E", "initials": "E", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Oncological Centre of Lublin, Medical Academy of Białystok." ], "valid": true, "equal_contr...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Animals", "Culture Techniques", "Disease Models, Animal", "Hydroxyethylrutoside", "Injections, Intraperitoneal", "Lung", "Radiation Dosage", "Radiation Injuries, Experimental", "Radiation-Protective Agents", "Rats", "Rats, Wistar", "Reference Values" ]
[ "Hydroxyethylrutoside/analogs & derivatives", "Lung/pathology", "Radiation Injuries, Experimental/prevention & control", "Radiation-Protective Agents/pharmacology" ]
[]
[ "pubmed:9972046" ]
9,972,048
null
null
The liver ultrastructure in caerulein and taurocholate acute pancreatitis in the rats.
The purpose of the study was to compare the morphological alterations of the liver in two models of acute pancreatitis: caerulein-induced (edematous) and taurocholate-induced (necro haemorrhagic one). The experiments were performed on 24 male, Wistar rats, weighing 240-260 g. In group I (n = 8) the supramaximal stimula...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
117-36
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "A Andrzejewska", "last_name": "Andrzejewska", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Acute Disease", "Animals", "Ceruletide", "Culture Techniques", "Disease Models, Animal", "Gastrointestinal Agents", "Liver", "Male", "Microscopy, Electron", "Pancreatitis", "Rats", "Rats, Wistar", "Reference Values", "Taurocholic Acid" ]
[ "Liver/ultrastructure", "Pancreatitis/chemically induced", "Pancreatitis/pathology" ]
[]
[ "pubmed:9972048" ]
9,972,049
null
null
Morphological brain damage, functional disorders and the possibilities of their treatment in children with infantile cerebral palsy.
Twenty-four children with infantile cerebral palsy (6 girls and 18 boys aged 3-17 years), surgically treated in the years 1993-1997, were involved in the study. Neurological-orthopaedic examinations and computer tomography (CT) of the head allowed precise diagnosis and understanding of its pathology. The group consiste...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
137-44
1999-03-05
2006-11-15
MEDLINE
ppublish
Print
null
[ { "display_name": "J Popko", "last_name": "Popko", "fore_name": "J", "initials": "J", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Children's Surgery, Medical Academy of Białystok." ], "valid": true, "equal_contrib": null ...
[ "Clinical Trial", "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Adolescent", "Brain", "Cerebral Palsy", "Child", "Child, Preschool", "Female", "Hemiplegia", "Humans", "Male", "Prognosis", "Quadriplegia", "Tomography, X-Ray Computed", "Treatment Outcome" ]
[ "Brain/pathology", "Cerebral Palsy/diagnosis", "Cerebral Palsy/rehabilitation" ]
[]
[ "pubmed:9972049" ]
9,972,047
null
null
Estimation of platelet function state in the course of trichinella spiralis infection.
Platelets are part of body defence system, especially the antiparasite immunologic response. Platelets manifest their functions only after their activation. Thrombin activates platelets inducing change of their shape and causing secretion of certain substances. This study was designed to estimate blood platelets morpho...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
110-6
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "J Matowicka-Karna", "last_name": "Matowicka-Karna", "fore_name": "J", "initials": "J", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Laboratory Diagnostics, Medical Academy of Białystok." ], "valid": true, ...
[ "Clinical Trial", "Comparative Study", "Controlled Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "Adolescent", "Adult", "Albendazole", "Animals", "Anthelmintics", "Female", "Humans", "Male", "Mebendazole", "Platelet Activation", "Platelet Count", "Reference Values", "Thrombocytosis", "Trichinella spiralis", "Trichinellosis" ]
[ "Platelet Activation/drug effects", "Platelet Activation/immunology", "Trichinella spiralis/isolation & purification", "Trichinellosis/drug therapy", "Trichinellosis/immunology" ]
[]
[ "pubmed:9972047" ]
9,972,050
null
null
The influence of sex and selected paragenetic and environmental factors on the basic anthropometric measurements of newborns in Bialystok.
On the basis of retrospective analysis of 1913 deliveries (40-weeks, single, from healthy mothers) that took place in Bialystok hospitals from 1 January to 31 December 1997, the influence of sex and selected paragenetic and environmental factors on the somatic development of newborns was assessed. Mathematical descript...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
145-53
1999-03-05
2004-11-17
MEDLINE
ppublish
Print
null
[ { "display_name": "E Litwiejko-Pietryńczak", "last_name": "Litwiejko-Pietryńczak", "fore_name": "E", "initials": "E", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Anatomy, Medical Academy of Białystok." ], "valid": true, "...
[ "Journal Article" ]
[ "eng" ]
[ "Anthropometry", "Environmental Exposure", "Female", "Genetics, Population", "Humans", "Infant, Newborn", "Male", "Poland", "Pregnancy", "Reference Values", "Retrospective Studies", "Risk Assessment", "Sex Characteristics" ]
[ "Anthropometry", "Environmental Exposure/analysis", "Infant, Newborn/growth & development" ]
[]
[ "pubmed:9972050" ]
9,972,051
null
null
Maternal blood group in ABO and Rh systems and somatic condition of newborns.
Maternal blood group in ABO and Rh systems and somatic conditions of newborns. A group of 5454 eutrophic newborns (2649 female and 2805 male) from Białystok were examined with respect to the following anthropometric features: body mass, crown-rump length (Si), head and chest circumferences and their, relation to the ma...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
154-9
1999-03-05
2004-11-17
MEDLINE
ppublish
Print
null
[ { "display_name": "E Litwiejko-Pietryńczak", "last_name": "Litwiejko-Pietryńczak", "fore_name": "E", "initials": "E", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Anatomy, Medical Academy of Białystok." ], "valid": true, "...
[ "Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "ABO Blood-Group System", "Adult", "Anthropology, Physical", "Anthropometry", "Female", "Humans", "Infant, Newborn", "Male", "Maternal-Fetal Exchange", "Pregnancy", "Rh-Hr Blood-Group System", "Sensitivity and Specificity", "Sex Characteristics", "Somatoform Disorders" ]
[ "ABO Blood-Group System/analysis", "Anthropometry", "Infant, Newborn/blood", "Maternal-Fetal Exchange/physiology", "Rh-Hr Blood-Group System/analysis", "Somatoform Disorders/blood" ]
[]
[ "pubmed:9972051" ]
9,972,052
null
null
Type II alveolar epithelial cells and cyclophosphamide-induced lung fibrosis.
The aim of the study was to evaluate the quantitative and morphological changes in type II alveolar epithelial cells in the course of cyclophosphamide-induced lung damage. The experiments used 40 Wistar rats, of 170 g body weight. The animals were divided into two experimental groups. Group I animals were given cycloph...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
160-8
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "S Sulkowski", "last_name": "Sulkowski", "fore_name": "S", "initials": "S", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal_contr...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Animals", "Antineoplastic Agents, Alkylating", "Basement Membrane", "Cell Culture Techniques", "Collagen", "Cyclophosphamide", "Disease Models, Animal", "Epithelial Cells", "Male", "Microscopy, Electron", "Pulmonary Alveoli", "Pulmonary Fibrosis", "Rats", "Rats, Wistar", "Reference Valu...
[ "Antineoplastic Agents, Alkylating/toxicity", "Cyclophosphamide/toxicity", "Pulmonary Alveoli/drug effects", "Pulmonary Alveoli/ultrastructure", "Pulmonary Fibrosis/chemically induced" ]
[]
[ "pubmed:9972052" ]
9,972,053
null
null
Involvement of nitric oxide in cardiovascular effects of cholecystokinin (CCK) in rats.
UNLABELLED: The aim of the present study was determinate the role of nitric oxide (NO) in the action of CCK on arterial blood pressure and function of isolated rat heart. Intravenous administration of NO synthase (NOS) inhibitor-NG-nitro-L-arginine methyl ester (L-NAME-100.0 micrograms/kg) increased arterial blood pres...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
169-85
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "R J Wiśniewska", "last_name": "Wiśniewska", "fore_name": "R J", "initials": "RJ", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pharmacology, Medical Academy of Białystok." ], "valid": true, "equal_contri...
[ "Comparative Study", "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Analysis of Variance", "Animals", "Blood Pressure", "Cardiovascular Physiological Phenomena", "Catecholamines", "Cholecystokinin", "Disease Models, Animal", "Dose-Response Relationship, Drug", "Drug Interactions", "Enzyme Inhibitors", "Male", "Myocardial Contraction", "NG-Nitroarginine Meth...
[ "Cardiovascular Physiological Phenomena/drug effects", "Cholecystokinin/pharmacology", "Nitric Oxide/biosynthesis" ]
[]
[ "pubmed:9972053" ]
9,972,054
null
null
Overexpression of the nucleolar organizer regions (NORs) in the thyroid follicular tumours. Comparison of the cytological and histopathological examinations.
The aim of the study was to determine the usefulness of the expression of argyrophilic nucleolar organizer region proteins (AgNORs) as a marker of malignancy degree in thyroid follicular tumours. The study used the postoperative material of thyroid glands and cytologic material obtained with fine needle aspiration biop...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
186-93
1999-03-05
2015-11-19
MEDLINE
ppublish
Print
null
[ { "display_name": "B Musiatowicz", "last_name": "Musiatowicz", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal_c...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Adenocarcinoma, Follicular", "Adenoma", "Biomarkers, Tumor", "Biopsy, Needle", "Diagnosis, Differential", "Female", "Humans", "Male", "Nuclear Proteins", "Nucleolus Organizer Region", "Reference Values", "Sensitivity and Specificity", "Thyroid Neoplasms" ]
[ "Adenocarcinoma, Follicular/pathology", "Adenoma/pathology", "Biomarkers, Tumor/analysis", "Nucleolus Organizer Region/chemistry", "Thyroid Neoplasms/pathology" ]
[]
[ "pubmed:9972054" ]
9,972,055
null
null
The activity of neutrophil myeloperoxidase in patients with renal cancer before and after embolization.
The activity of granulocytic myeloperoxidase (MPO) was investigated in 45 patients with renal cancer before and 14 days after renal artery embolization in comparison with control group of 40 healthy people. The group examined showed lower MPO activity before embolization, as compared to controls. The differences being ...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
194-200
1999-03-05
2015-11-19
MEDLINE
ppublish
Print
null
[ { "display_name": "M Mantur", "last_name": "Mantur", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Laboratory Diagnostics, Medical Academy of Białystok." ], "valid": true, "equal_contrib": ...
[ "Clinical Trial", "Comparative Study", "Controlled Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "Adult", "Biomarkers, Tumor", "Embolization, Therapeutic", "Female", "Humans", "Kidney Neoplasms", "Male", "Middle Aged", "Neoplasm Staging", "Neutrophils", "Peroxidase", "Reference Values", "Sensitivity and Specificity" ]
[ "Biomarkers, Tumor/analysis", "Embolization, Therapeutic", "Kidney Neoplasms/blood", "Kidney Neoplasms/therapy", "Neutrophils/enzymology", "Peroxidase/metabolism" ]
[]
[ "pubmed:9972055" ]
9,972,056
null
null
Prolidase as a prodrug converting enzyme. II. Synthesis of proline analogue of anthraquinone-2-carboxylic acid and its susceptibility to the action of prolidase.
The feasibility to targeting prolidase as an antineoplastic prodrug--converting enzyme has been examined. The synthesis of proline analogue of anthraquinone-2-carboxylic acid (potential antineoplastic agent) conjugated through imido-bond (potential target for prolidase action) has been performed. The product was found ...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
201-9
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "A Bielawska", "last_name": "Bielawska", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Medicinal Chemistry and Drug Technology, Medical Academy of Białystok." ], "valid": tru...
[ "Journal Article" ]
[ "eng" ]
[ "Anthraquinones", "Antineoplastic Agents", "Carboxylic Acids", "Dipeptidases", "Prodrugs", "Proline", "Solubility" ]
[ "Anthraquinones/chemistry", "Antineoplastic Agents/chemical synthesis", "Antineoplastic Agents/chemistry", "Carboxylic Acids/chemistry", "Dipeptidases/chemistry", "Prodrugs/chemistry", "Proline/chemistry" ]
[]
[ "pubmed:9972056" ]
9,972,057
null
null
Western blot banding pattern in early Lyme borreliosis among patients from an endemic region of north-eastern Poland.
Aim of this study was evaluation of Western blot banding patterns in different clinical forms of early Lyme borreliosis diagnosed in patients from north-eastern Poland, recognized as endemic for tick-borne diseases. Study was performed on serum samples of 48 patients with Lyme borreliosis and 26 healthy volunteers, as ...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
210-20
1999-03-05
2006-11-15
MEDLINE
ppublish
Print
null
[ { "display_name": "R Flisiak", "last_name": "Flisiak", "fore_name": "R", "initials": "R", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Infectious Diseases, Medical Academy of Białystok." ], "valid": true, "equal_contrib": ...
[ "Clinical Trial", "Comparative Study", "Controlled Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "Acute Disease", "Antibodies, Bacterial", "Blotting, Western", "Borrelia burgdorferi Group", "Endemic Diseases", "Female", "Humans", "Immunoenzyme Techniques", "Immunoglobulin G", "Immunoglobulin M", "Linear Models", "Lyme Disease", "Male", "Poland", "Sensitivity and Specificity", "Ser...
[ "Blotting, Western", "Borrelia burgdorferi Group/isolation & purification", "Lyme Disease/diagnosis", "Lyme Disease/epidemiology" ]
[]
[ "pubmed:9972057" ]
9,972,059
null
null
The influence of epsilon-aminocaproic acid derivatives on the anticoagulant activity of heparin.
Derivatives of epsilon-aminocaproic acid with antifibrinolytic activity, at low concentration, do not influence the anticoagulant activity of heparin under the heparin-thrombin test conditions. At concentrations higher than 0.002 M tested compounds slightly enhance the anticoagulant action of heparin.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
228-31
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "K Midura-Nowaczek", "last_name": "Midura-Nowaczek", "fore_name": "K", "initials": "K", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Chemistry, University of Bialystok, Poland." ], "valid": true, "equal_co...
[ "Journal Article" ]
[ "eng" ]
[ "Aminocaproates", "Anticoagulants", "Blood Coagulation", "Dose-Response Relationship, Drug", "Drug Interactions", "Heparin", "Humans" ]
[ "Aminocaproates/pharmacology", "Anticoagulants/pharmacology", "Blood Coagulation/drug effects", "Heparin/pharmacology" ]
[]
[ "pubmed:9972059" ]
9,972,058
null
null
The activity of enzymes oxidizing alcohols in the liver of rats after methanol intoxication measured with fluorogenic substrates.
The activities of alcohol dehydrogenase isoenzymes (class ADH I and ADH II) and aldehyde dehydrogenase (ALDH) were measured using fluorogenic substrates in the liver of rats. Animals were dosed with 6 g of methanol/kg b.w. after 6, 12, 24 hours and 2, 5 and 7 days. Liver ADH I and ADH II activities were gradually incre...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
221-7
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "L Chrostek", "last_name": "Chrostek", "fore_name": "L", "initials": "L", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Biochemical Diagnostics, Medical Academy of Białystok." ], "valid": true, "equal_cont...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Alcohol Dehydrogenase", "Aldehyde Dehydrogenase", "Analysis of Variance", "Animals", "Disease Models, Animal", "Fluorescent Dyes", "Fluorometry", "Liver", "Male", "Methanol", "Naphthalenes", "Rats", "Rats, Wistar", "Reference Values", "Substrate Specificity" ]
[ "Alcohol Dehydrogenase/metabolism", "Aldehyde Dehydrogenase/metabolism", "Liver/enzymology", "Methanol/toxicity" ]
[]
[ "pubmed:9972058" ]
9,972,061
null
null
Cathepsin D inhibitor from Vicia sativa L.
Specific inhibitor of cathepsin D has been shown in the extract of Vicia sativa L. seeds. This inhibitor does not inhibit the activity of other aspartic proteases. Also it does not inhibit the activity of cysteine proteases and serine proteases.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
245-9
1999-03-05
2014-11-20
MEDLINE
ppublish
Print
null
[ { "display_name": "W Roszkowska-Jakimiec", "last_name": "Roszkowska-Jakimiec", "fore_name": "W", "initials": "W", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Instrumental Analysis, Medical Academy of Białystok, Poland." ], "v...
[ "Journal Article" ]
[ "eng" ]
[ "Cathepsin D", "Endopeptidases", "Fabaceae", "In Vitro Techniques", "Plant Extracts", "Plants, Medicinal", "Seeds", "Species Specificity" ]
[ "Cathepsin D/antagonists & inhibitors", "Endopeptidases/analysis", "Plant Extracts/analysis", "Seeds/chemistry" ]
[]
[ "pubmed:9972061" ]
9,972,060
null
null
The mechanism of the silent zone on Lorenz plots in atrial fibrillation.
Lorenz plot is an acknowledged method of the evaluation of sequences of ventricular beats in cardiac arrhythmias, particularly in atrial fibrillation. Lorenz plots are scatterplots that show the R-R intervals as a function of the preceding R-R intervals. The authors of this paper conducted studies of 83 cases of atrial...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
232-44
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "W Pedich", "last_name": "Pedich", "fore_name": "W", "initials": "W", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Gerontology, Medical Academy of Białystok." ], "valid": true, "equal_contrib": null }, ...
[ "Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "Atrial Fibrillation", "Cardiovascular Physiological Phenomena", "Digoxin", "Electrocardiography", "Heart Conduction System", "Humans", "Normal Distribution", "Sensitivity and Specificity" ]
[ "Atrial Fibrillation/diagnosis", "Electrocardiography" ]
[]
[ "pubmed:9972060" ]
9,972,063
null
null
Epidemiology of erythema migrans in north-eastern Poland.
The aim of the study was to evaluate erythema migrans (EM) prevalence and treatment in north-eastern Poland during the last 25 years. The material for the study consisted of data sent to the Department of Dermatology by physicians from fifteen regional out-patient clinics. They were collected according to specially pre...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
271-7
1999-03-05
2004-11-17
MEDLINE
ppublish
Print
null
[ { "display_name": "B Chodynicka", "last_name": "Chodynicka", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Dermatology and Venereology, Medical Academy, Białystok." ], "valid": true, "equa...
[ "Journal Article" ]
[ "eng" ]
[ "Adolescent", "Adult", "Age Distribution", "Aged", "Aged, 80 and over", "Anti-Bacterial Agents", "Child", "Child, Preschool", "Erythema Chronicum Migrans", "Female", "Humans", "Male", "Middle Aged", "Poland", "Prevalence", "Retrospective Studies", "Risk Factors", "Seasons", "Sex ...
[ "Anti-Bacterial Agents/therapeutic use", "Erythema Chronicum Migrans/drug therapy", "Erythema Chronicum Migrans/epidemiology" ]
[]
[ "pubmed:9972063" ]
9,972,062
null
null
Effects of sulfated cholecystokinin octapeptide and cholecystokinin tetrapeptide in rat behavior after blockade of nitric oxide synthase by L-NAME.
This study was conducted to determine what, if any, role L-NAME (inhibitor of nitric oxide synthase) plays in the behavioral effects induced by sulfated cholecystokinin octapeptide CCK-8) and cholecystokinin tetrapeptide (CCK-4) in adult male rats. The motility, stereotypy, anxiety, extinction of conditioned avoidance ...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
250-70
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "Z Hoły", "last_name": "Hoły", "fore_name": "Z", "initials": "Z", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pharmacology, Medical Academy of Białystok." ], "valid": true, "equal_contrib": null }, {...
[ "Comparative Study", "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Analysis of Variance", "Animals", "Behavior, Animal", "Brain", "Disease Models, Animal", "Dopamine Agents", "Male", "NG-Nitroarginine Methyl Ester", "Nitric Oxide Synthase", "Rats", "Rats, Wistar", "Sincalide", "Tetragastrin" ]
[ "Behavior, Animal/drug effects", "Dopamine Agents/pharmacology", "NG-Nitroarginine Methyl Ester/pharmacology", "Nitric Oxide Synthase/antagonists & inhibitors", "Sincalide/pharmacology", "Tetragastrin/pharmacology" ]
[]
[ "pubmed:9972062" ]
9,972,065
null
null
Nitrates and nitrites contents in whole-day's diets of men--workers of metal industry.
An evaluation of nitrates and nitrites in daily diets of 239 men was performed. It was found that daily intake of these compounds did not exceed the acceptable values.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
287-91
1999-03-05
2006-11-15
MEDLINE
ppublish
Print
null
[ { "display_name": "M Borawska", "last_name": "Borawska", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Laboratory of Bromatology, Medical Academy of Białystok." ], "valid": true, "equal_contrib": null ...
[ "Clinical Trial", "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Adult", "Diet", "Eating", "Environmental Monitoring", "Food Analysis", "Food Contamination", "Humans", "Male", "Metallurgy", "Middle Aged", "Nitrates", "Nitrites", "Nutrition Assessment", "Poland" ]
[ "Environmental Monitoring/methods", "Food Analysis", "Food Contamination/analysis", "Metallurgy", "Nitrates/analysis", "Nitrites/analysis" ]
[]
[ "pubmed:9972065" ]
9,972,064
null
null
Inhibitors of pepsin, trypsin and chymotrypsin in seeds of plants consumed by humans and animals. I. Evaluation of pepsin, trypsin, and chymotrypsin inhibitors activity in seeds of 26 plant species.
Antipepsin, antitrypsin and antichymotrypsin activity was determined in seed extracts of 26 plants consumed by humans and animals (small bean, broad bean, pumpkin, kidney bean, charlock, pea, buckwheat, barley, maize, flax, lupine, poppy, almond, peanut, hazel, walnut, oat, millet, wheat, rice, rape, sunflower, lentils...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
278-86
1999-03-05
2004-11-17
MEDLINE
ppublish
Print
null
[ { "display_name": "A Bańkowska", "last_name": "Bańkowska", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Instrumental Analysis Medical Academy of Białystok." ], "valid": true, "equal_contr...
[ "Journal Article" ]
[ "eng" ]
[ "Animals", "Chymotrypsin", "Fabaceae", "Humans", "Pepsin A", "Plant Extracts", "Plants, Edible", "Plants, Medicinal", "Seeds", "Trypsin Inhibitors" ]
[ "Chymotrypsin/antagonists & inhibitors", "Pepsin A/antagonists & inhibitors", "Plant Extracts/analysis", "Plants, Edible/chemistry", "Seeds/chemistry", "Trypsin Inhibitors/analysis" ]
[]
[ "pubmed:9972064" ]
9,972,066
null
null
Nitroblue tetrazolium test in patients with renal tumor in the course of embolization.
The main role of neutrophilic granulocytes is phagocytosis and destruction of phagocytized bacteria. The nitroblue tetrazolium test (NBT), used to evaluate the bactericidal function of granulocytes, was assessed in 45 patients with renal tumour before and 14 days after renal artery embolization. No statistically signif...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
292-7
1999-03-05
2004-11-17
MEDLINE
ppublish
Print
null
[ { "display_name": "M Mantur", "last_name": "Mantur", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Laboratory Diagnostics, Medical Academy of Białystok." ], "valid": true, "equal_contrib": ...
[ "Clinical Trial", "Controlled Clinical Trial", "Journal Article" ]
[ "eng" ]
[ "Adenocarcinoma", "Adult", "Embolization, Therapeutic", "Female", "Granulocytes", "Humans", "Indicators and Reagents", "Kidney Neoplasms", "Male", "Middle Aged", "Nitroblue Tetrazolium", "Reference Values", "Renal Artery", "Sensitivity and Specificity" ]
[ "Adenocarcinoma/diagnosis", "Adenocarcinoma/therapy", "Embolization, Therapeutic", "Granulocytes/chemistry", "Indicators and Reagents/analysis", "Kidney Neoplasms/diagnosis", "Kidney Neoplasms/therapy", "Nitroblue Tetrazolium/analysis" ]
[]
[ "pubmed:9972066" ]
9,972,068
null
null
Metallothioneins in rats exposed to cadmium.
It was found that intoxication of rats with cadmium results in a significant increase of metallothioneins content in various organs, especially in kidneys and liver and in lower degree in spleen, muscle, brain and heart.
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
309-13
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "B Floriańczyk", "last_name": "Floriańczyk", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Physiological Chemistry, Medical Academy of Lublin." ], "valid": true, "equal_c...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Animals", "Brain", "Cadmium", "Culture Techniques", "Disease Models, Animal", "Heart", "Kidney", "Liver", "Lung", "Metallothionein", "Myocardium", "Rats", "Rats, Wistar" ]
[ "Cadmium/toxicity", "Metallothionein/biosynthesis", "Metallothionein/drug effects" ]
[]
[ "pubmed:9972068" ]
9,972,067
null
null
Fetotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) in rats.
The fetotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated. Histological and histochemical changes in the liver of newborn, jung and adult rats exposed to the herbicide from the prenatal period to the end of an experiment were evaluated. The experiment used 90 male and female, Wistar, aged to 10 we...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
298-308
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "M Sulik", "last_name": "Sulik", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal_contrib": nul...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "2,4-Dichlorophenoxyacetic Acid", "Animals", "Disease Models, Animal", "Female", "Fetus", "Herbicides", "Immunohistochemistry", "Liver", "Male", "Pregnancy", "Pregnancy, Animal", "Rats", "Rats, Wistar", "Reference Values" ]
[ "2,4-Dichlorophenoxyacetic Acid/toxicity", "Fetus/drug effects", "Herbicides/toxicity", "Liver/drug effects", "Liver/pathology", "Pregnancy, Animal/drug effects" ]
[]
[ "pubmed:9972067" ]
9,972,069
null
null
Ultrastructural changes in rat hepatocytes in acute intoxication with 2,4-dichlorophenoxyacetic acid (2,4-D).
The hepatotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated. Ultrastructural changes were evaluated in transmission electron microscope. The experiment used 60 male Wistar rats divided into two groups: I--control-18 animals and II--42 animals which received chemically pure 2,4-D acid by gastric ga...
Roczniki Akademii Medycznej w Bialymstoku (1995)
1,998
null
null
null
null
false
null
Rocz Akad Med Bialymst
9515551
Poland
43
null
314-26
1999-03-05
2013-11-21
MEDLINE
ppublish
Print
null
[ { "display_name": "M Sulik", "last_name": "Sulik", "fore_name": "M", "initials": "M", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pathological Anatomy, Medical Academy of Białystok." ], "valid": true, "equal_contrib": nul...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "2,4-Dichlorophenoxyacetic Acid", "Acute Disease", "Animals", "Cell Survival", "Cells, Cultured", "Disease Models, Animal", "Herbicides", "Liver", "Male", "Rats", "Rats, Wistar", "Reference Values" ]
[ "2,4-Dichlorophenoxyacetic Acid/toxicity", "Herbicides/toxicity", "Liver/drug effects", "Liver/ultrastructure" ]
[]
[ "pubmed:9972069" ]
9,974,149
null
10.1016/s0165-0173(98)00046-0
An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration.
There is mounting evidence for mitochondrial involvement in neurodegenerative diseases including Alzheimer's and Parkinson's disease and amyotrophic lateral sclerosis. Mitochondrial DNA mutations, whether inherited or acquired, lead to impaired electron transport chain (ETC) functioning. Impaired electron transport, in...
Brain research. Brain research reviews
1,999
1
null
null
null
false
null
Brain Res Brain Res Rev
8908638
Netherlands
29
1
1-25
1999-04-13
2019-11-02
MEDLINE
ppublish
Print
null
[ { "display_name": "D S Cassarino", "last_name": "Cassarino", "fore_name": "D S", "initials": "DS", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Medical Scientist Training Program, University of Virginia Health Sciences Center, Charlottesville 22908...
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, U.S. Gov't, P.H.S.", "Review" ]
[ "eng" ]
[ "Animals", "Cell Death", "Cell Nucleus", "Humans", "Mitochondria", "Mutation", "Neurodegenerative Diseases", "Oxidative Stress" ]
[ "Cell Nucleus/physiology", "Mitochondria/physiology", "Mutation/physiology", "Neurodegenerative Diseases/physiopathology", "Oxidative Stress/physiology" ]
[]
[ "pubmed:9974149", "pii:S0165017398000460", "doi:10.1016/s0165-0173(98)00046-0" ]
9,974,150
null
10.1016/s0165-0173(98)00047-2
The planum temporale: a systematic, quantitative review of its structural, functional and clinical significance.
The planum temporale (PT) is a triangular area situated on the superior temporal gyrus (STG), which has enjoyed a resurgence of interest across several disciplines, including neurology, psychiatry and psychology. Traditionally, the planum is thought to be larger on the left side of the brain in the majority of normal s...
Brain research. Brain research reviews
1,999
1
null
null
null
false
null
Brain Res Brain Res Rev
8908638
Netherlands
29
1
26-49
1999-04-13
2022-03-17
MEDLINE
ppublish
Print
null
[ { "display_name": "J Shapleske", "last_name": "Shapleske", "fore_name": "J", "initials": "J", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Psychological Medicine, King's College School of Medicine and Dentistry, London, UK." ], ...
[ "Journal Article", "Review" ]
[ "eng" ]
[ "Cadaver", "Dyslexia", "Functional Laterality", "Humans", "Magnetic Resonance Imaging", "Schizophrenia", "Sex Characteristics", "Temporal Lobe", "Tomography, X-Ray Computed" ]
[ "Temporal Lobe/anatomy & histology", "Temporal Lobe/physiology" ]
[]
[ "pubmed:9974150", "pii:S0165017398000472", "doi:10.1016/s0165-0173(98)00047-2" ]
9,974,151
null
10.1016/s0165-0173(98)00048-4
Branching and/or collateral projections of spinal dorsal horn neurons.
Branching and/or collateral projections of spinal dorsal horn neurons is a common phenomenon. Evidence is presented for the existence of STTm/STTl, STTc/STTi, STT/SMT, STT/SRT, SCT/DCPS, SST/DCPS, SCT/SST, STT/SHT, STeT/SHT, STeTs and other doubly or multiply projecting spinal neurons that have been anatomically and ph...
Brain research. Brain research reviews
1,999
1
null
null
null
false
null
Brain Res Brain Res Rev
8908638
Netherlands
29
1
50-82
1999-04-13
2019-11-02
MEDLINE
ppublish
Print
null
[ { "display_name": "G W Lu", "last_name": "Lu", "fore_name": "G W", "initials": "GW", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Neurobiology, Capital University of Medical Sciences, Beijing, China." ], "valid": true, "eq...
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, U.S. Gov't, P.H.S.", "Review" ]
[ "eng" ]
[ "Animals", "Axons", "Humans", "Neurons", "Spinal Cord", "Synaptic Transmission" ]
[ "Axons/ultrastructure", "Neurons/physiology", "Neurons/ultrastructure", "Spinal Cord/physiology", "Spinal Cord/ultrastructure", "Synaptic Transmission/physiology" ]
[]
[ "pubmed:9974151", "pii:S0165017398000484", "doi:10.1016/s0165-0173(98)00048-4" ]
9,974,152
null
10.1016/s0165-0173(98)00050-2
Metabotropic glutamate receptors: electrophysiological properties and role in plasticity.
Electrophysiological research on mGluRs is now very extensive, and it is clear that activation of mGluRs results in a large number of diverse cellular actions. Studies of mGluRs and on ionic channels has clearly demonstrated that mGluR activation has a widespread and potent inhibitory action on both voltage-gated Ca2+ ...
Brain research. Brain research reviews
1,999
1
null
null
null
false
null
Brain Res Brain Res Rev
8908638
Netherlands
29
1
83-120
1999-04-13
2019-11-02
MEDLINE
ppublish
Print
null
[ { "display_name": "R Anwyl", "last_name": "Anwyl", "fore_name": "R", "initials": "R", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Physiology, Trinity College, Dublin, Ireland. ranwyl@mail.tcd.ie" ], "valid": true, "equal_...
[ "Journal Article", "Review" ]
[ "eng" ]
[ "Animals", "Electrophysiology", "Neuronal Plasticity", "Receptors, Metabotropic Glutamate" ]
[ "Neuronal Plasticity/physiology", "Receptors, Metabotropic Glutamate/physiology" ]
[]
[ "pubmed:9974152", "pii:S0165017398000502", "doi:10.1016/s0165-0173(98)00050-2" ]
9,974,153
null
10.1016/s0165-0173(98)00049-6
Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration.
Amyotrophic lateral sclerosis (ALS) is a devastating neurologic disease that rapidly progresses from mild motor symptoms to severe motor paralysis and premature death. Until recently, there were few substantive studies conducted on the pathogenesis of the disease. With the genetic linkage of mutations in the superoxide...
Brain research. Brain research reviews
1,999
1
null
null
null
false
null
Brain Res Brain Res Rev
8908638
Netherlands
29
1
121-35
1999-04-13
2019-11-02
MEDLINE
ppublish
Print
null
[ { "display_name": "B M Morrison", "last_name": "Morrison", "fore_name": "B M", "initials": "BM", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Neurobiology of Aging Laboratories, Mount Sinai School of Medicine, New York, NY 10029, USA. morrison@cort...
[ "Journal Article", "Review" ]
[ "eng" ]
[ "Amyotrophic Lateral Sclerosis", "Animals", "Humans", "Mice", "Mice, Transgenic", "Mutation", "Nerve Degeneration", "Superoxide Dismutase" ]
[ "Amyotrophic Lateral Sclerosis/genetics", "Mutation/physiology", "Nerve Degeneration/genetics", "Superoxide Dismutase/genetics" ]
[]
[ "pubmed:9974153", "pii:S0165017398000496", "doi:10.1016/s0165-0173(98)00049-6" ]
9,974,154
null
10.1016/s0165-3806(98)00149-7
Mu- and delta-opioid receptor densities in respiratory-related brainstem regions of neonatal swine.
The piglet displays similar postnatal development in respiration and sleep-wake behavior to the human. To shed light on the possible influence of opioid systems on these functions, this study assessed the density of mu- and delta-opioid receptors in brainstems of 2-3 and 5-7 (young), 14-17 (intermediate) and 20-21 (old...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
1-9
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "A Laferrière", "last_name": "Laferrière", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pediatrics, McGill University, Montreal, Quebec, Canada." ], "valid": true, "equa...
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, U.S. Gov't, P.H.S." ]
[ "eng" ]
[ "Analgesics", "Analgesics, Opioid", "Animals", "Animals, Newborn", "Binding Sites", "Brain Stem", "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-", "Enkephalin, D-Penicillamine (2,5)-", "Enkephalins", "Receptors, Opioid, delta", "Receptors, Opioid, mu", "Respiratory Physiological Phenomena", "Swine", ...
[ "Animals, Newborn/metabolism", "Brain Stem/physiology", "Receptors, Opioid, delta/metabolism", "Receptors, Opioid, mu/metabolism", "Respiratory Physiological Phenomena", "Swine/metabolism" ]
[]
[ "pubmed:9974154", "pii:S0165380698001497", "doi:10.1016/s0165-3806(98)00149-7" ]
9,974,155
null
10.1016/s0165-3806(98)00150-3
Ontogeny of rolipram-sensitive, low-K(m), cyclic AMP-specific phosphodiesterase in rat brain.
The postnatal development of rolipram-sensitive, low-K(m), cyclic AMP-specific phosphodiesterase (PDE4) was investigated in discrete regions of rat brain using a PDE4 activity assay and immunoblot analyses with K116, a PDE4 antibody. The Vmax for cyclic AMP hydrolysis by PDE4 was lower at birth when compared to adult l...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
11-9
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "K Zhang", "last_name": "Zhang", "fore_name": "K", "initials": "K", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Pharmacology and Therapeutics, Louisiana State University School of Medicine, Shreveport 71130, USA. kz...
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, U.S. Gov't, P.H.S." ]
[ "eng" ]
[ "3',5'-Cyclic-AMP Phosphodiesterases", "Aging", "Animals", "Animals, Newborn", "Brain", "Cyclic AMP", "Cyclic Nucleotide Phosphodiesterases, Type 4", "Female", "Hydrolysis", "Immunoblotting", "Kinetics", "Male", "Pyrrolidinones", "Rats", "Rats, Sprague-Dawley", "Rolipram", "Tissue Di...
[ "3',5'-Cyclic-AMP Phosphodiesterases/metabolism", "Aging/metabolism", "Animals, Newborn/metabolism", "Brain/enzymology", "Pyrrolidinones/pharmacology" ]
[]
[ "pubmed:9974155", "pii:S0165380698001503", "doi:10.1016/s0165-3806(98)00150-3" ]
9,974,156
null
10.1016/s0165-3806(98)00151-5
Change of expression of full-length and truncated TrkBs in the developing monkey central nervous system.
We examined the expression of full-length TrkB (TrkBTK+) and truncated TrkB (TrkBTK-) in the central nervous system (CNS) of the macaque monkey (Macaca fascicularis) using a western blot analysis. At the adult stage, the levels of TrkBTK+ in cerebral cortices were higher than those in other structures of CNS and the ex...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
21-9
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "K Ohira", "last_name": "Ohira", "fore_name": "K", "initials": "K", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University, Aichi, Japan." ], ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "Brain", "Central Nervous System", "Cerebral Cortex", "Embryo, Mammalian", "Embryonic and Fetal Development", "Macaca fascicularis", "Peptide Fragments", "Receptor Protein-Tyrosine Kinases", "Receptor, Ciliary Neurotrophic Factor", "Receptors, Nerve Gr...
[ "Aging/metabolism", "Animals, Newborn/metabolism", "Central Nervous System/embryology", "Central Nervous System/growth & development", "Peptide Fragments/metabolism", "Receptor Protein-Tyrosine Kinases/metabolism", "Receptors, Nerve Growth Factor/metabolism" ]
[]
[ "pubmed:9974156", "pii:S0165380698001515", "doi:10.1016/s0165-3806(98)00151-5" ]
9,974,157
null
10.1016/s0165-3806(98)00152-7
Changes in mRNA levels for group I metabotropic glutamate receptors following in utero hypoxia-ischemia.
The expression of group I metabotropic glutamate receptors (mGluR1 and mGluR5) and inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) mRNA was studied by in situ hybridization in the developing rat hippocampus after in utero hypoxia-ischemia. In utero hypoxia-ischemia was induced by clamping the uterine blood vessels...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
31-7
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "A Simonyi", "last_name": "Simonyi", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Departments of Biochemistry and Pathology, University of Missouri, Columbia 65212, USA." ], "valid": true...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "Calcium Channels", "Dentate Gyrus", "Fetal Diseases", "Hippocampus", "Hypoxia", "In Situ Hybridization", "Inositol 1,4,5-Trisphosphate Receptors", "Ischemia", "RNA, Messenger", "Rats", "Rats, Sprague-Dawley", "Receptors, Cytoplasmic and Nuclear", ...
[ "Fetal Diseases/metabolism", "Hypoxia/metabolism", "Ischemia/metabolism", "RNA, Messenger/metabolism", "Receptors, Metabotropic Glutamate/genetics" ]
[]
[ "pubmed:9974157", "pii:S0165380698001527", "doi:10.1016/s0165-3806(98)00152-7" ]
9,974,158
null
10.1016/s0165-3806(98)00156-4
Distribution and developmental changes in metabotropic glutamate receptor messenger RNA expression in the rat lumbar spinal cord.
Using in situ hybridisation, the regional distribution of primary transcripts and splice variants of all metabotropic glutamate receptor subtypes (mGluR) currently known to be expressed in the spinal cord have been studied in the lumbar enlargement of the rat spinal cord. In adult animals, the messenger RNA of the mGlu...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
39-53
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "A Berthele", "last_name": "Berthele", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Neurology, Technical University Munich, Germany. achim.berthele@neuro.med.tu-muenchen.de" ], ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "DNA, Recombinant", "Genetic Variation", "Lumbosacral Region", "RNA, Messenger", "Rats", "Rats, Sprague-Dawley", "Receptors, Metabotropic Glutamate", "Spinal Cord", "Tissue Distribution" ]
[ "RNA, Messenger/metabolism", "Receptors, Metabotropic Glutamate/genetics", "Spinal Cord/metabolism" ]
[]
[ "pubmed:9974158", "pii:S0165380698001564", "doi:10.1016/s0165-3806(98)00156-4" ]
9,974,159
null
10.1016/s0165-3806(98)00157-6
Maturation of visual receptive field properties in the rat superior colliculus.
Visually responsive neurons were recorded in the superficial layers of rat superior colliculus from postnatal day 12 to 28. Receptive field properties such as size, type (ON, OFF, ON-OFF and motion sensitive) and direction selectivity were analyzed to disclose changes during maturation. Although some aspects of sensory...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
55-64
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "S Fortin", "last_name": "Fortin", "fore_name": "S", "initials": "S", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Département de Sciences Biologiques, Université de Montréal, Québec, Canada." ], "valid": true, "equal_...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "Brain Mapping", "Electrophysiology", "Photic Stimulation", "Rats", "Rats, Long-Evans", "Reaction Time", "Superior Colliculi", "Visual Pathways" ]
[ "Aging/physiology", "Animals, Newborn/physiology", "Superior Colliculi/growth & development", "Visual Pathways/growth & development" ]
[]
[ "pubmed:9974159", "pii:S0165380698001576", "doi:10.1016/s0165-3806(98)00157-6" ]
9,974,160
null
10.1016/s0165-3806(98)00162-x
Developmental plasticity of ascending spinal axons studies using the North American opossum, Didelphis virginiana.
The objectives of the present study were to determine if axons of all ascending tracts grow through the lesion after transection of the thoracic spinal cord during development in the North American opossum, and if so, whether they reach regions of the brain they normally innervate. Opossum pups were subjected to transe...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
65-77
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "J R Terman", "last_name": "Terman", "fore_name": "J R", "initials": "JR", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, College of Medicine, Columbus 432...
[ "Journal Article", "Research Support, U.S. Gov't, P.H.S." ]
[ "eng" ]
[ "Afferent Pathways", "Aging", "Animals", "Animals, Newborn", "Axons", "Brain", "Denervation", "Neuronal Plasticity", "Opossums", "Spinal Cord", "Thorax" ]
[ "Afferent Pathways/growth & development", "Aging/physiology", "Animals, Newborn/physiology", "Axons/physiology", "Neuronal Plasticity/physiology", "Spinal Cord/physiology" ]
[]
[ "pubmed:9974160", "pii:S016538069800162X", "doi:10.1016/s0165-3806(98)00162-x" ]
9,974,161
null
10.1016/s0165-3806(98)00163-1
Development of O4+/O1- immunopanned pro-oligodendroglia in vitro.
In this study, O4+/O1- pro-oligodendroglia isolated by immunopanning from cerebral hemispheres of P3-P5 rats were evaluated during their maturation in culture. Immunopanning yielded 3-4 x 10(5) cells/cerebrum, with 98% O4+ and 6% O1+. There was heterogeneity in the morphologies of immunopanned cells ranging from simple...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
79-87
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "C A Ingraham", "last_name": "Ingraham", "fore_name": "C A", "initials": "CA", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Psychiatry, Albany Medical College, NY 12208, USA. christine_ingraham@ccgateway.amc.edu" ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Animals", "Animals, Newborn", "Antibodies, Monoclonal", "Cattle", "Cells, Cultured", "Cellular Senescence", "Fetal Blood", "Glial Fibrillary Acidic Protein", "Immunologic Techniques", "Microscopy, Phase-Contrast", "Myelin Basic Protein", "Oligodendroglia", "Rats", "Rats, Sprague-Dawley", ...
[ "Oligodendroglia/physiology", "Stem Cells/physiology" ]
[]
[ "pubmed:9974161", "pii:S0165380698001631", "doi:10.1016/s0165-3806(98)00163-1" ]
9,974,162
null
10.1016/s0165-3806(98)00167-9
Regional distribution of cerebral blood volume and cerebral blood flow in newborn piglets--effect of hypoxia/hypercapnia.
The relationship between regional parenchymal cerebral blood volume (CBV), regional cerebral blood flow (CBF) and the calculated mean transit time (MTT) was investigated in 14 newborn piglets. The effects of combined hypoxic hypoxia (PaO2 = 32 +/- 5 mm Hg) and hypercapnia (paCO2 = 68 +/- 5 mm Hg) were measured in seven...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
89-98
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "R Bauer", "last_name": "Bauer", "fore_name": "R", "initials": "R", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Pathophysiology, Friedrich Schiller University, Jena, Germany. rbau@mti-n.uni-jena.de" ], "valid...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Animals", "Animals, Newborn", "Blood Flow Velocity", "Blood Volume", "Cerebrovascular Circulation", "Female", "Hypercapnia", "Hypoxia", "Male", "Microspheres", "Regional Blood Flow", "Swine" ]
[ "Animals, Newborn/physiology", "Blood Volume/physiology", "Cerebrovascular Circulation/physiology", "Hypercapnia/physiopathology", "Hypoxia/physiopathology" ]
[]
[ "pubmed:9974162", "pii:S0165380698001679", "doi:10.1016/s0165-3806(98)00167-9" ]
9,974,163
null
10.1016/s0165-3806(98)00155-2
Neurotrophic factors BDNF and GDNF protect embryonic chick spinal cord motoneurons from ethanol neurotoxicity in vivo.
Maternal consumption of ethanol is widely recognized as a leading cause of mental and physical deficits. Many populations of the central nervous system are affected by the teratogenic effects of ethanol. Neurotrophic factors (NTFs) have been shown to protect against ethanol neurotoxicity in culture, although there have...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
99-106
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "D M Bradley", "last_name": "Bradley", "fore_name": "D M", "initials": "DM", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "University of Florida Brain Institute, Gainesville 32610-0244, USA." ], "valid": true, "equal_co...
[ "Journal Article", "Research Support, U.S. Gov't, Non-P.H.S.", "Research Support, U.S. Gov't, P.H.S." ]
[ "eng" ]
[ "Animals", "Brain-Derived Neurotrophic Factor", "Cell Count", "Cell Size", "Chick Embryo", "Ethanol", "Glial Cell Line-Derived Neurotrophic Factor", "Motor Neurons", "Nerve Growth Factors", "Nerve Tissue Proteins", "Neuroprotective Agents", "Neurotoxins", "Spinal Cord" ]
[ "Brain-Derived Neurotrophic Factor/pharmacology", "Ethanol/poisoning", "Motor Neurons/drug effects", "Nerve Growth Factors", "Nerve Tissue Proteins/pharmacology", "Neuroprotective Agents/pharmacology", "Neurotoxins/pharmacology", "Spinal Cord/embryology" ]
[]
[ "pubmed:9974163", "pii:S0165380698001552", "doi:10.1016/s0165-3806(98)00155-2" ]
9,974,164
null
10.1016/s0165-3806(98)00161-8
Delayed neuronal loss after administration of intracerebroventricular kainic acid to preweanling rats.
Excitotoxins, such as kainic acid (KA), have been shown to produce both immediate and delayed neuronal degeneration in adult rat brain. While preweanling rats have been shown to be resistant to the immediate neurotoxicity of KA, the presence of delayed neuronal loss has not been investigated in such animals. To determi...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
107-16
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "E M Montgomery", "last_name": "Montgomery", "fore_name": "E M", "initials": "EM", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Psychology, College of Arts and Sciences, Washington University, St. Louis, MO 63110, US...
[ "Journal Article", "Research Support, Non-U.S. Gov't", "Research Support, U.S. Gov't, P.H.S." ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Suckling", "Cell Count", "Female", "Glial Fibrillary Acidic Protein", "HSP70 Heat-Shock Proteins", "Hippocampus", "Immunohistochemistry", "Injections, Intraventricular", "Kainic Acid", "Male", "Neurons", "Proto-Oncogene Proteins c-jun", "Rats", "Rats, Spra...
[ "Animals, Suckling/physiology", "Hippocampus/drug effects", "Hippocampus/pathology", "Kainic Acid/pharmacology", "Neurons/drug effects" ]
[]
[ "pubmed:9974164", "pii:S0165380698001618", "doi:10.1016/s0165-3806(98)00161-8" ]
9,974,165
null
10.1016/s0165-3806(98)00171-0
Neuronal activity influences the growth of barrels in developing rat primary somatosensory cortex without affecting the expression pattern of four major GABAA receptor alpha subunits.
Thalamic innervation plays a major role in parcellation of neocortex and maturation of cortical circuits. While the underlying mechanisms are unknown, lesion studies have identified GABAA receptors in neocortex as molecular targets of thalamic regulation [J. Paysan, A. Kossel, J. Bolz, J.M. Fritschy, Area-specific regu...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
117-27
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "S Penschuck", "last_name": "Penschuck", "fore_name": "S", "initials": "S", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Institute of Pharmacology, University of Zurich, Switzerland." ], "valid": true, "equal_contrib":...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Animals", "Brain-Derived Neurotrophic Factor", "Dizocilpine Maleate", "Drug Implants", "Excitatory Amino Acid Antagonists", "Immunohistochemistry", "Isomerism", "Neurons", "Polyvinyls", "Rats", "Rats, Sprague-Dawley", "Receptors, GABA-A", "Receptors, N-Methyl-D-Aspartate", "Somatosensory ...
[ "Neurons/physiology", "Receptors, GABA-A/metabolism", "Somatosensory Cortex/growth & development", "Somatosensory Cortex/metabolism" ]
[]
[ "pubmed:9974165", "pii:S0165380698001710", "doi:10.1016/s0165-3806(98)00171-0" ]
9,974,166
null
10.1016/s0165-3806(98)00153-9
Apoptosis in early ocular morphogenesis in the mouse.
Development of the eye requires complex interactions between tissues, extracellular matrix and growth factors. Most cells of the optic primordia grow and differentiate into discrete ocular structures; however, other cells have death as their developmental fate. The most common mechanisms of cell death are apoptosis and...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
129-33
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "L K Laemle", "last_name": "Laemle", "fore_name": "L K", "initials": "LK", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Anatomy, Cell Biology and Injury Sciences, UMDNJ, New Jersey Medical School, Newark 07103, USA. ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Animals", "Apoptosis", "Embryo, Mammalian", "Embryonic and Fetal Development", "Eye", "Image Processing, Computer-Assisted", "In Situ Nick-End Labeling", "Mice", "Mice, Inbred C57BL" ]
[ "Apoptosis/physiology", "Eye/embryology" ]
[]
[ "pubmed:9974166", "pii:S0165380698001539", "doi:10.1016/s0165-3806(98)00153-9" ]
9,974,167
null
10.1016/s0165-3806(98)00154-0
Naltrindole administration during the preweanling period and manipulation affect adrenocortical reactivity in young rats.
The effect of a daily injection of the delta-selective opioid antagonist naltrindole (1 mg/kg), from birth to postnatal day 19, on basal and post-stress corticosterone levels in 25-day old rats of both sexes was investigated. The effects of manipulation were studied by including two control groups, one group received d...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
135-7
1999-04-13
2019-12-10
MEDLINE
ppublish
Print
null
[ { "display_name": "B Fernández", "last_name": "Fernández", "fore_name": "B", "initials": "B", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Departamento de Biología Animal II, Facultad de Biología, Universidad Complutense, Madrid, Spain." ], ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Adrenal Cortex", "Animals", "Animals, Suckling", "Corticosterone", "Female", "Handling, Psychological", "Male", "Naltrexone", "Narcotic Antagonists", "Rats", "Rats, Wistar", "Receptors, Opioid, delta", "Sex Characteristics", "Stress, Physiological", "Swimming", "Temperature", "Water...
[ "Adrenal Cortex/drug effects", "Adrenal Cortex/physiology", "Animals, Suckling/physiology", "Handling, Psychological", "Naltrexone/analogs & derivatives", "Narcotic Antagonists/pharmacology" ]
[]
[ "pubmed:9974167", "pii:S0165380698001540", "doi:10.1016/s0165-3806(98)00154-0" ]
9,974,168
null
10.1016/s0165-3806(98)00158-8
Pentylenetetrazol seizures induce cell suffering but not death in the immature rat brain.
To investigate whether long-term functional consequences of status epilepticus (SE) induced by pentylenetetrazol in 10-day-old rats correlated with cell injury and/or death, acid fuchsin and TUNEL staining were performed between 4 to 144 h after SE. Acid fuchsin stained hippocampus, amygdala and cerebral cortex at 24 h...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
139-44
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "N Pineau", "last_name": "Pineau", "fore_name": "N", "initials": "N", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "INSERM U 398, Faculté de Médecine, Strasbourg, France." ], "valid": true, "equal_contrib": null }, ...
[ "Journal Article" ]
[ "eng" ]
[ "Animals", "Animals, Newborn", "Benzenesulfonates", "Brain", "Cell Death", "Coloring Agents", "Convulsants", "In Situ Nick-End Labeling", "Pentylenetetrazole", "Rats", "Rats, Sprague-Dawley", "Status Epilepticus", "Time Factors" ]
[ "Animals, Newborn/physiology", "Brain/pathology", "Convulsants", "Pentylenetetrazole", "Status Epilepticus/chemically induced", "Status Epilepticus/pathology" ]
[]
[ "pubmed:9974168", "pii:S0165380698001588", "doi:10.1016/s0165-3806(98)00158-8" ]
9,974,169
null
10.1016/s0165-3806(98)00159-x
The maturation of corticocollicular neurons in mice.
The location and development of the neurons that give rise to the corticocollicular projection were studied in C57BL/6J and 129SV/CPorJ anophthalmic mice. The first neurons that project to the superior colliculus appear in the subplate zone at E13 in C57BL/6J mice. Cortical plate neurons reach the colliculus about 2 da...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
145-8
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "M Y Khachab", "last_name": "Khachab", "fore_name": "M Y", "initials": "MY", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Biomedical Sciences, Creighton University, Omaha, NE 68178-0405, USA. mahak@bif11.creighton.ed...
[ "Journal Article" ]
[ "eng" ]
[ "Animals", "Cellular Senescence", "Cerebral Cortex", "Embryo, Mammalian", "Embryonic and Fetal Development", "Eye Abnormalities", "Mice", "Mice, Inbred C57BL", "Mice, Mutant Strains", "Neurons", "Reference Values", "Superior Colliculi" ]
[ "Cerebral Cortex/embryology", "Neurons/physiology", "Superior Colliculi/embryology" ]
[]
[ "pubmed:9974169", "pii:S016538069800159X", "doi:10.1016/s0165-3806(98)00159-x" ]
9,974,170
null
10.1016/s0165-3806(98)00169-2
Bcl-2 and Bax expression following methylazoxymethanol acetate-induced apoptosis in the external granule cell layer of the developing rat cerebellum.
Since Bcl-2 protects a variety of cell types from programmed cell death, whereas Bax promotes apoptosis, the present study examines Bcl-2 and Bax proteins, and bcl-2 and bax mRNA expression in the developing cerebellum of the rat following methylazoxymethanol (MAM) acetate administration by using immunohistochemistry, ...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
149-53
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "E López", "last_name": "López", "fore_name": "E", "initials": "E", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Unitat de Neuropatologia, Hospital Prínceps d'Espanya (Bellvitge), Barcelona, Spain." ], "valid": true, "...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "Apoptosis", "Cerebellum", "DNA Fragmentation", "Methylazoxymethanol Acetate", "Proto-Oncogene Proteins", "Proto-Oncogene Proteins c-bcl-2", "Rats", "Rats, Sprague-Dawley", "bcl-2-Associated X Protein" ]
[ "Aging/metabolism", "Animals, Newborn/metabolism", "Apoptosis/physiology", "Cerebellum/metabolism", "Proto-Oncogene Proteins/metabolism", "Proto-Oncogene Proteins c-bcl-2/metabolism" ]
[]
[ "pubmed:9974170", "pii:S0165380698001692", "doi:10.1016/s0165-3806(98)00169-2" ]
9,974,171
null
10.1016/s0165-3806(98)00170-9
Differential sensitivity of tachykinin vs. enkephalin gene expression in the posterior striatum in response to acute p-chloroamphetamine treatment during postnatal development.
The acute effects of the monoamine releaser p-chloroamphetamine (pCA, 10 mg/kg, i.p.) on preprotachykinin (PPT) and preproenkephalin (PPE) mRNA expression in the anterior (A-STR) vs. posterior (P-STR) striatum were studied in rodents at postnatal days (PND) 10, 21 and 35. Northern analysis 4 h post-injection yielded no...
Brain research. Developmental brain research
1,999
1
11
0165-3806
null
false
0165-3806
Brain Res Dev Brain Res
8908639
Netherlands
112
1
155-7
1999-04-13
2019-08-31
MEDLINE
ppublish
Print
null
[ { "display_name": "G J Basura", "last_name": "Basura", "fore_name": "G J", "initials": "GJ", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA." ...
[ "Journal Article" ]
[ "eng" ]
[ "Aging", "Animals", "Animals, Newborn", "Corpus Striatum", "Enkephalins", "Gene Expression", "Protein Precursors", "RNA, Messenger", "Rats", "Rats, Sprague-Dawley", "Serotonin Agents", "Tachykinins", "Tissue Distribution", "p-Chloroamphetamine" ]
[ "Animals, Newborn/growth & development", "Corpus Striatum/physiology", "Enkephalins/genetics", "Gene Expression/drug effects", "Serotonin Agents/pharmacology", "Tachykinins/genetics", "p-Chloroamphetamine/pharmacology" ]
[]
[ "pubmed:9974171", "pii:S0165380698001709", "doi:10.1016/s0165-3806(98)00170-9" ]
9,989,474
null
10.1002/(sici)1099-1263(199901/02)19:1<25::aid-jat537>3.0.co;2-q
Exposure of Rana ridibunda to lead I. Study of lead accumulation in various tissues and hepatic delta-aminolevulinic acid dehydratase activity.
There are few data at present on the impact of lead (Pb) on amphibians, although declines in amphibian populations due to man-made changes in the environment have been recorded in recent years. The impact of Pb in adult frogs, Rana ridibunda, was therefore examined. Animals were exposed to 14 mg l(-1) (ppm) aqueous Pb ...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
25-9
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "A K Vogiatzis", "last_name": "Vogiatzis", "fore_name": "A K", "initials": "AK", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Zoology, University of Thessaloniki, Greece." ], "valid": true, "equal_contrib...
[ "Journal Article" ]
[ "eng" ]
[ "Animals", "Biomarkers", "Body Weight", "Female", "Lead", "Liver", "Organ Size", "Porphobilinogen Synthase", "Rana ridibunda", "Survival Rate", "Time Factors" ]
[ "Lead/toxicity", "Liver/enzymology", "Porphobilinogen Synthase/metabolism" ]
[]
[ "pubmed:9989474", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<25::AID-JAT537>3.0.CO;2-Q", "doi:10.1002/(sici)1099-1263(199901/02)19:1<25::aid-jat537>3.0.co;2-q" ]
9,989,472
null
10.1002/(sici)1099-1263(199901/02)19:1<13::aid-jat531>3.0.co;2-e
Hexachlorocyclohexane-induced behavioural and neurochemical changes in rat.
Effect of chronic oral exposure (10 and 20 mg kg(-1) body wt. for 7, 15 and 30 days) to hexachlorocyclohexane (HCH) on open-field behaviour and activities of cerebral Na+,K+-ATPase, Mg2+-ATPase and acetylcholinesterase (AChE) of rat was evaluated. Motor and grooming activities were altered, whereas vertical exploratory...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
13-8
1999-04-29
2019-12-10
MEDLINE
ppublish
Print
null
[ { "display_name": "A Sahoo", "last_name": "Sahoo", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Zoology, S.V.M. College, Jagatsinghpur, Orissa, India." ], "valid": true, "equal_contrib": ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Acetylcholinesterase", "Animals", "Behavior, Animal", "Brain", "Ca(2+) Mg(2+)-ATPase", "Hexachlorocyclohexane", "Insecticides", "Neurotransmitter Agents", "Rats", "Rats, Wistar", "Sodium-Potassium-Exchanging ATPase", "Time Factors" ]
[ "Behavior, Animal/drug effects", "Brain/enzymology", "Hexachlorocyclohexane/toxicity", "Insecticides/toxicity", "Neurotransmitter Agents/metabolism" ]
[]
[ "pubmed:9989472", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<13::AID-JAT531>3.0.CO;2-E", "doi:10.1002/(sici)1099-1263(199901/02)19:1<13::aid-jat531>3.0.co;2-e" ]
9,989,476
null
10.1002/(sici)1099-1263(199901/02)19:1<39::aid-jat534>3.0.co;2-m
Partial and weak oestrogenicity of the red wine constituent resveratrol: consideration of its superagonist activity in MCF-7 cells and its suggested cardiovascular protective effects.
It was recently reported that the red wine phytoestrogen resveratrol (RES) acts as a superagonist to oestrogen-responsive MCF-7 cells. This activity of RES was speculated to be relevant to the 'French paradox' in which moderate red wine consumption is reported to yield cardiovascular health benefits to humans. We repor...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
39-45
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "J Ashby", "last_name": "Ashby", "fore_name": "J", "initials": "J", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Zeneca Central Toxicology Laboratory, Macclesfield, Cheshire, UK." ], "valid": true, "equal_contrib": nul...
[ "Comparative Study", "Journal Article" ]
[ "eng" ]
[ "Animals", "Binding, Competitive", "Cardiovascular System", "Cell Line", "Diethylstilbestrol", "Estradiol", "Estrogens", "Female", "Fungi", "Plasmids", "Rats", "Receptors, Estrogen", "Resveratrol", "Stilbenes", "Transfection", "Uterus", "Wine" ]
[ "Cardiovascular System/drug effects", "Estrogens/pharmacology", "Stilbenes/pharmacology" ]
[]
[ "pubmed:9989476", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<39::AID-JAT534>3.0.CO;2-M", "doi:10.1002/(sici)1099-1263(199901/02)19:1<39::aid-jat534>3.0.co;2-m" ]
9,989,478
null
10.1002/(sici)1099-1263(199901/02)19:1<55::aid-jat538>3.0.co;2-k
Profile of reactive oxygen species generation and antioxidative mechanisms in the maturing rat kidney.
The antioxidative potential and reactive oxygen species generation were assessed in rat kidney during early critical periods of development and maturation. Superoxide anion generation was found to be low in kidney during early postnatal days of development, whereas hydrogen peroxide levels remained unaltered during dev...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
55-9
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "A Gupta", "last_name": "Gupta", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Predictive Toxicology Research Group, Industrial Toxicology Research Centre, Lucknow, India." ], "valid": tru...
[ "Comparative Study", "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Animals", "Animals, Newborn", "Antioxidants", "Female", "Hydrogen Peroxide", "Kidney", "Male", "Oxidative Stress", "Pregnancy", "Rats", "Reactive Oxygen Species", "Superoxides" ]
[ "Antioxidants/metabolism", "Kidney/metabolism", "Oxidative Stress/physiology", "Reactive Oxygen Species/metabolism" ]
[]
[ "pubmed:9989478", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<55::AID-JAT538>3.0.CO;2-K", "doi:10.1002/(sici)1099-1263(199901/02)19:1<55::aid-jat538>3.0.co;2-k" ]
9,989,471
null
10.1002/(sici)1099-1263(199901/02)19:1<7::aid-jat529>3.0.co;2-g
Ochratoxicosis: prevention of developmental toxicity by L-methionine in rats.
L-Methionine was found to inhibit the developmental toxicity induced by ochratoxin A (OA) in pregnant female rats. The fetuses had significantly lower weights. Dams and fetuses treated with OA had visceral and skeletal anomalies, while combined treatment with L-methionine and OA showed no significant changes when compa...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
7-12
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "M A Abdel-Wahhab", "last_name": "Abdel-Wahhab", "fore_name": "M A", "initials": "MA", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Mycotoxins Laboratory, National Research Center, Dokki, Cairo, Egypt." ], "valid": true, ...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Abnormalities, Drug-Induced", "Animals", "Body Weight", "Bone and Bones", "Drug Interactions", "Female", "Fetus", "Male", "Methionine", "Ochratoxins", "Pregnancy", "Random Allocation", "Rats", "Rats, Sprague-Dawley", "Teratogens", "Viscera" ]
[ "Abnormalities, Drug-Induced/prevention & control", "Fetus/drug effects", "Methionine/pharmacology", "Ochratoxins/toxicity", "Teratogens/toxicity" ]
[]
[ "pubmed:9989471", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<7::AID-JAT529>3.0.CO;2-G", "doi:10.1002/(sici)1099-1263(199901/02)19:1<7::aid-jat529>3.0.co;2-g" ]
9,989,473
null
10.1002/(sici)1099-1263(199901/02)19:1<19::aid-jat533>3.0.co;2-r
Inhalation of substance P and thiorphan: acute toxicity and effects on respiration in conscious guinea pigs.
Substance P is a tachykinin and a biologically active neuropeptide. The peptide produces salivation, neuronal excitation, vasodilatation, increased vascular permeability and contraction of smooth muscles in the respiratory tract. The study was designed to evaluate the acute effects in guinea pigs of inhaled aerosolized...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
19-23
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "B L Koch", "last_name": "Koch", "fore_name": "B L", "initials": "BL", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Defence Research Establishment, Department of Biomedicine, Umeå, Sweden. koch@ume.foa.se" ], "valid": true...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Administration, Inhalation", "Animals", "Dose-Response Relationship, Drug", "Drug Synergism", "Guinea Pigs", "Lung Diseases", "Male", "Protease Inhibitors", "Respiration", "Substance P", "Survival Rate", "Thiorphan", "Tidal Volume", "Time Factors" ]
[ "Lung Diseases/chemically induced", "Protease Inhibitors/toxicity", "Respiration/drug effects", "Substance P/toxicity", "Thiorphan/toxicity" ]
[]
[ "pubmed:9989473", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<19::AID-JAT533>3.0.CO;2-R", "doi:10.1002/(sici)1099-1263(199901/02)19:1<19::aid-jat533>3.0.co;2-r" ]
9,989,475
null
10.1002/(sici)1099-1263(199901/02)19:1<31::aid-jat535>3.0.co;2-6
Acridine-induced subcellular and functional changes in isolated human hepatocytes in vitro.
Acridines are nucleic acid intercalating compounds with properties relating to the complexity of their structure. Tetrahydroaminoacridine (tacrine, Cognex), a simple acridine, is a reversible inhibitor of cholinesterase activity available for the symptomatic treatment of Alzheimer's disease. Tacrine therapy causes spor...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
31-8
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "D R Plymale", "last_name": "Plymale", "fore_name": "D R", "initials": "DR", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Pathology and Experimental Toxicology Department, Parke-Davis Pharmaceutical Research, Division of Warner-La...
[ "Journal Article" ]
[ "eng" ]
[ "Acridines", "Cells, Cultured", "Endoplasmic Reticulum", "Fluorescence", "Humans", "Intracellular Membranes", "Liver", "Membrane Potentials", "Microscopy, Electron", "Mitochondria, Liver", "Permeability" ]
[ "Acridines/toxicity", "Endoplasmic Reticulum/drug effects", "Liver/drug effects", "Mitochondria, Liver/drug effects" ]
[]
[ "pubmed:9989475", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<31::AID-JAT535>3.0.CO;2-6", "doi:10.1002/(sici)1099-1263(199901/02)19:1<31::aid-jat535>3.0.co;2-6" ]
9,989,470
null
10.1002/(sici)1099-1263(199901/02)19:1<1::aid-jat527>3.0.co;2-3
Effects of ibuprofen on arylamine N-acetyltransferase activity in human colon tumor cells.
The inhibition of arylamine N-acetyltransferase (NAT) activity by ibuprofen was determined in a human colon tumour (adenocarcinoma) cell line. Two assay systems were employed, one with cellular cytosols (9000 g supernatant) and the other with intact colon tumour cell suspensions. The NAT activity in a human colon tumou...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
1-6
1999-04-29
2019-09-21
MEDLINE
ppublish
Print
null
[ { "display_name": "J G Chung", "last_name": "Chung", "fore_name": "J G", "initials": "JG", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Department of Microbiology, China Medical College, Taichung, Taiwan, Republic of China." ], "valid": tru...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "2-Acetylaminofluorene", "4-Aminobenzoic Acid", "Adenocarcinoma", "Aged", "Arylamine N-Acetyltransferase", "Carcinogens", "Colonic Neoplasms", "Dose-Response Relationship, Drug", "Fluorenes", "Humans", "Ibuprofen", "Male", "Tumor Cells, Cultured" ]
[ "Adenocarcinoma/enzymology", "Arylamine N-Acetyltransferase/metabolism", "Colonic Neoplasms/enzymology", "Ibuprofen/pharmacology" ]
[]
[ "pubmed:9989470", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<1::AID-JAT527>3.0.CO;2-3", "doi:10.1002/(sici)1099-1263(199901/02)19:1<1::aid-jat527>3.0.co;2-3" ]
9,989,480
null
10.1002/(sici)1099-1263(199901/02)19:1<67::aid-jat540>3.0.co;2-#
Effect of pyrethroid-based liquid mosquito repellent inhalation on the blood-brain barrier function and oxidative damage in selected organs of developing rats.
Pesticides have been implicated in various neurological disorders in humans and experimental animals. Our earlier studies have demonstrated a high vulnerability of developing blood-brain barrier (BBB) towards very low level exposure of quinalphos, cypermethrin and lindane. Earlier it has been observed that a cypermethr...
Journal of applied toxicology : JAT
1,999
null
null
0260-437X
null
false
0260-437X
J Appl Toxicol
8109495
England
19
1
67-72
1999-04-29
2019-12-10
MEDLINE
ppublish
Print
null
[ { "display_name": "A Gupta", "last_name": "Gupta", "fore_name": "A", "initials": "A", "suffix": null, "collective_name": null, "orcid": null, "affiliations": [ "Predictive Toxicology Research Group, Industrial Toxicology Research Centre, Lucknow, India." ], "valid": tru...
[ "Journal Article", "Research Support, Non-U.S. Gov't" ]
[ "eng" ]
[ "Administration, Inhalation", "Aging", "Allethrins", "Animals", "Animals, Newborn", "Blood-Brain Barrier", "Brain", "Female", "Glutathione", "Insect Repellents", "Kidney", "Lipid Peroxides", "Liver", "Oxidative Stress", "Rats" ]
[ "Aging", "Allethrins/toxicity", "Blood-Brain Barrier/drug effects", "Brain/metabolism", "Insect Repellents/toxicity", "Oxidative Stress/drug effects" ]
[]
[ "pubmed:9989480", "pii:10.1002/(SICI)1099-1263(199901/02)19:1<67::AID-JAT540>3.0.CO;2-#", "doi:10.1002/(sici)1099-1263(199901/02)19:1<67::aid-jat540>3.0.co;2-#" ]
End of preview. Expand in Data Studio

PubMed Metadata V2

Snapshot of PubMed citation metadata, augmented with PMC records that were not safely represented in PubMed's current PMID-to-PMCID mapping.

The PubMed portion was built from the NLM PubMed 2026 annual baseline and daily update XML files through pubmed26n1592.xml.gz. Updates are applied in numeric order, revised records replace earlier versions, and citations whose latest event is a deletion are omitted. The dataset was built on 2026-08-16.

The single train split contains 41,860,640 records:

  • 40,990,549 records have a unique, non-null PMID;
  • 870,091 PMC-only records have a null PMID and are keyed by PMCID;
  • 879,135 validated PMC records were added to the current PubMed snapshot; and
  • 2,553 existing PMID rows were safely updated with their missing PMCID and available metadata.

Open-access flag

is_oa is a non-null operational full-text accessibility flag:

pmcid is present
OR
(issn, eissn, or issn_linking matches a current DOAJ journal
 AND publication year >= that journal's all-content open-license start year)
  • 12,906,383 rows are marked is_oa=true.
  • 12,338,603 rows have a PMCID; every one is marked is_oa=true.
  • 567,780 rows are marked open through the date-aware DOAJ rule without a PMCID.

This flag indicates practical full-text accessibility. It does not assert that an article has a permissive reuse license: PMC content has article-specific rights, and users must check the applicable license before reuse.

Columns

Column Type Description
pmid uint32 PubMed identifier; unique when present. Null for PMC-only records without a safely resolved PMID.
pmcid string PubMed Central identifier, when available.
doi string Digital Object Identifier, normalized to its identifier value.
title string Article or book-document title as plain text.
abstract string Abstract sections joined with newlines; section labels are retained.
journal string Full journal title.
year uint16 Best available publication year.
publication_month uint8 Explicit publication month, when available.
publication_day uint8 Explicit publication day, when available.
issn string Print ISSN.
eissn string Electronic ISSN.
is_oa boolean PMCID-or-date-aware-DOAJ accessibility flag described above.
issn_linking string NLM linking ISSN used to associate journal formats and title histories.
journal_abbrev string NLM/ISO journal abbreviation.
nlm_unique_id string NLM Catalog identifier for the journal.
country string Journal publication country recorded by NLM.
volume string Journal volume; kept as text because values are not always numeric.
issue string Journal issue; kept as text because values are not always numeric.
pages string Pagination or electronic location text.
date_completed date Date NLM completed processing the citation.
date_revised date Most recent explicit revision date in the record.
citation_status string PubMed/Medline citation status.
publication_status string PubMed publication status such as ppublish or epublish.
pub_model string Print/electronic publication model.
vernacular_title string Title in the original language, when supplied separately.
authors list of structs Ordered authors, including names, ORCID, affiliations, validity, and equal-contribution metadata.
publication_types list of strings NLM publication-type labels.
languages list of strings PubMed language codes.
mesh_terms list of strings MeSH descriptor headings assigned to the citation.
mesh_major_topics list of strings MeSH descriptors or descriptor/qualifier combinations marked as major topics.
keywords list of strings Author, publisher, or indexing keywords.
article_ids list of strings Identifier values carried in the source record.

Each element of authors has this structure:

display_name: string
last_name: string
fore_name: string
initials: string
suffix: string
collective_name: string
orcid: string
affiliations: list[string]
valid: bool
equal_contrib: bool

Sources and terms

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