PGS Sample Set (PSS)
large_stringlengths
9
9
Polygenic Score (PGS) ID
large_stringlengths
9
2.77k
Number of Individuals
int64
1
5.33M
Number of Cases
float64
0
389k
Number of Controls
float64
0
1.14M
Percent of Participants Who are Male
float64
0
100
Sample Age
large_stringclasses
733 values
Broad Ancestry Category
large_stringclasses
73 values
Ancestry (e.g. French, Chinese)
large_stringclasses
90 values
Country of Recruitment
large_stringclasses
140 values
Additional Ancestry Description
large_stringclasses
131 values
Phenotype Definitions and Methods
large_stringclasses
798 values
Followup Time
large_stringclasses
141 values
GWAS Catalog Study ID (GCST...)
large_stringclasses
8 values
Source PubMed ID (PMID)
float64
1.25M
39.9M
Source DOI
large_stringclasses
13 values
Cohort(s)
large_stringclasses
460 values
Additional Sample/Cohort Information
large_stringclasses
245 values
PSS000209
PGS000119
20,468
884
19,584
46.9
mean:54.2;sd:15.9;unit:years
European
null
USA
null
Basal cell carcinoma: ICD9-173.01,173.11,173.21,173.31,173.41,173.51,173.61,173.71,173.81,173.91
null
null
null
null
MGI
null
PSS000210
PGS000118
29,898
2,718
27,180
45.9
mean:57.7;sd:8.1;unit:years
European
null
UK
White British Subset
PheCode 172.11
null
null
null
null
UKB
null
PSS000211
PGS000118, PGS000119, PGS000120
149,857
13,624
136,233
45.9
mean:57.7;sd:8.1;unit:years
European
null
UK
White British Subset
PheCode 172
null
null
null
null
UKB
null
PSS000212
PGS000121
902
null
null
0
mean:70.1;sd:7.0;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000212
PGS000121
557
null
null
100
mean:69.5;sd:5.9;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000213
PGS000121, PGS000122
902
95
807
0
mean:70.1;sd:7.0;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000213
PGS000121, PGS000122
557
135
422
100
mean:69.5;sd:5.9;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000214
PGS000121, PGS000122
902
395
507
0
mean:70.1;sd:7.0;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000214
PGS000121, PGS000122
557
135
422
100
mean:69.5;sd:5.9;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000215
PGS000121, PGS000122
902
166
736
0
mean:70.1;sd:7.0;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000215
PGS000121, PGS000122
557
53
504
100
mean:69.5;sd:5.9;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000216
PGS000121, PGS000122
902
103
799
0
mean:70.1;sd:7.0;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000216
PGS000121, PGS000122
557
9
548
100
mean:69.5;sd:5.9;unit:years
European
null
Australia
null
null
null
null
null
null
DOES
null
PSS000217
PGS000016
10,303
239
10,064
17.1
null
European
null
NR
null
Phenotypic information was self-reported by the individual through an online, interactive health history tool
null
null
null
null
CG
Samples are individuals whose healthcare provider had ordered a Color Genomics multi-gene panel test
PSS000218
PGS000007
9,529
828
8,701
0
null
European
null
NR
null
Phenotypic information was self-reported by the individual through an online, interactive health history tool
null
null
null
null
CG
Samples are individuals whose healthcare provider had ordered a Color Genomics multi-gene panel test
PSS000219
PGS000013
11,010
126
10,884
17.1
null
European
null
NR
null
Phenotypic information was self-reported by the individual through an online, interactive health history tool
null
null
null
null
CG
Samples are individuals whose healthcare provider had ordered a Color Genomics multi-gene panel test
PSS000220
PGS000067
56,994
26,419
30,575
100
null
European, East Asian, African American or Afro-Caribbean, Oceanian, Hispanic or Latin American, South Asian, African unspecified, NR
null
Australia, Belgium, Bulgaria, Canada, China, Denmark, EU, Finland, France, French West Indies, Germany, Malaysia, Norway, Poland, Portugal, Spain, Sweden, The Netherlands, UK, USA
Combined analysis of multiple ancestries, including: European, East Asian, African American, Hawaiian, Hispanic American, South Asian, Black African, Black Caribbean, and Other (not specified)
Age of onset of aggressive prostate cancer, defined by Gleason score ≥7, PSA ≥10 ng/mL, T3-T4 stage, nodal metastases, or distant metastases
null
null
null
null
OncoArray_Prostate
List of Cohorts available from dbGaP: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001391.v1.p1
PSS000221
PGS000067
4,437
1,424
3,013
100
null
African unspecified
null
Canada, France, French West Indies, UK, USA
Subset of OncoArray_APC_onset samples. Determined from genetic PCs via FastPop
Age of onset of aggressive prostate cancer, defined by Gleason score ≥7, PSA ≥10 ng/mL, T3-T4 stage, nodal metastases, or distant metastases
null
null
null
null
OncoArray_Prostate
List of Cohorts available from dbGaP: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001391.v1.p1
PSS000222
PGS000067
1,901
716
1,185
100
null
Asian unspecified
null
Australia, Canada, China, Denmark, EU, Finland, France, Germany, Malaysia, Norway, Poland, Spain, Sweden, The Netherlands, UK, USA
Subset of OncoArray_APC_onset samples. Determined from genetic PCs via FastPop
Age of onset of aggressive prostate cancer, defined by Gleason score ≥7, PSA ≥10 ng/mL, T3-T4 stage, nodal metastases, or distant metastases
null
null
null
null
OncoArray_Prostate
List of Cohorts available from dbGaP: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001391.v1.p1
PSS000223
PGS000067
50,656
24,279
26,377
100
null
European
null
Australia, Belgium, Bulgaria, Canada, Denmark, EU, Finland, France, Germany, Malaysia, Norway, Poland, Portugal, Spain, Sweden, The Netherlands, UK, USA
Subset of OncoArray_APC_onset samples. Determined from genetic PCs via FastPop
Age of onset of aggressive prostate cancer, defined by Gleason score ≥7, PSA ≥10 ng/mL, T3-T4 stage, nodal metastases, or distant metastases
null
null
null
null
OncoArray_Prostate
List of Cohorts available from dbGaP: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001391.v1.p1
PSS000224
PGS000067
34,558
3,983
30,575
100
mean:70.0;iqr:[63.0,76.0];unit:years
European, East Asian, African American or Afro-Caribbean, Oceanian, Hispanic or Latin American, South Asian, African unspecified, NR
null
Australia, Belgium, Bulgaria, Canada, China, Denmark, EU, Finland, France, French West Indies, Germany, Malaysia, Norway, Poland, Portugal, Spain, Sweden, The Netherlands, UK, USA
Combined analysis of multiple ancestries, including: European, East Asian, African American, Hawaiian, Hispanic American, South Asian, Black African, Black Caribbean, and Other (not specified)
Age at death due to prostate cancer.
null
null
null
null
OncoArray_Prostate
List of Cohorts available from dbGaP: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001391.v1.p1
PSS000225
PGS000123
469
334
135
55.223881
null
European
null
NR
null
null
null
null
null
null
PPMI
Both the PPMI and WUSTL datasets are available by request from the PPMI website (www.ppmi-info.org)
PSS000226
PGS000123
786
493
293
58.26972
null
European
null
USA
null
null
null
null
null
null
WUSTL
Both the PPMI and WUSTL datasets are available by request from the PPMI website (www.ppmi-info.org)
PSS000227
PGS000013
544
40
504
null
null
Asian unspecified
null
USA
null
null
null
null
null
null
VIRGO|MESA
Cases are from VIRGO, controls are from MESA
PSS000228
PGS000013
1,298
336
962
null
null
African American or Afro-Caribbean
null
USA
null
null
null
null
null
null
VIRGO|MESA
Cases are from VIRGO, controls are from MESA
PSS000229
PGS000013
919
168
751
null
null
Hispanic or Latin American
null
USA
null
null
null
null
null
null
VIRGO|MESA
Cases are from VIRGO, controls are from MESA
PSS000230
PGS000013
3,081
1,537
1,544
null
null
European
null
USA
null
null
null
null
null
null
VIRGO|MESA
Cases are from VIRGO, controls are from MESA
PSS000231
PGS000124
4,672
1,734
2,938
null
null
European
null
Australia
null
Advanced primary open-angle glaucoma
null
null
null
null
ANZRAG
Samples come from Phase 1 and Phase 2 of ANZRAG.
PSS000232
PGS000125
7,746
2,499
5,247
39.646269
null
Hispanic or Latin American
Central American, Cuban, Dominican, Mexican, Puerto Rican, South American
USA
Ancestry groups were defined based on a combination of self-identified Hispanic/Latino background and genetic similarity
Individuals with T2D were defined as those with fasting time >8 h and fasting glucose levels ≥126 mg/dL, fasting ≤8 h and fasting glucose ≥200 mg/dL, post–oral glucose tolerance test glucose ≥200 mg/dL, HbA1c ≥6.5% (48 mmol/mol), or on current treatment with antihyperglycemia medications.
null
null
null
null
HCHS-SOL
null
PSS000233
PGS000126
334,880
4,908
329,972
null
null
European
null
UK
White British subset, unrelated
Gout identified by self-report at the inclusion visit, individuals with an ICD-10 for gout (M10) in hospital admissions who did not self-report gout were excluded from the analysis.
null
null
25,826,379
null
UKB
null
PSS000234
PGS000128, PGS000131
1,906
262
1,644
37.932844
mean:57.4;sd:7.43;unit:years
African unspecified
null
USA
null
Incident type 2 diabtes defined as fasting glucose >= 7 mmol/L, 2 hour glucose >= 11.1 mmol/L, antidiabetic medication use, or a physician diagnosis of type 2 diabetes
range:[10.0,15.0];unit:years
null
null
null
ARIC|MESA
Partial overlap with discovery GWAS
PSS000235
PGS000129, PGS000132
5,073
2,391
2,682
47.44727
mean:55.6;sd:7.37;unit:years
East Asian
null
USA, Singapore
null
Incident type 2 diabtes defined as fasting glucose >= 7 mmol/L, 2 hour glucose >= 11.1 mmol/L, antidiabetic medication use, or a physician diagnosis of type 2 diabetes
range:[10.0,15.0];unit:years
null
null
null
MESA|SCHS
Partial overlap with discovery GWAS
PSS000236
PGS000127, PGS000130
37,357
13,145
24,212
43.472442
mean:54.63;sd:8.27;unit:years
European
null
USA, France, Germany, Italy, The Netherlands, Spain, Sweden, UK
null
Incident type 2 diabtes defined as fasting glucose >= 7 mmol/L, 2 hour glucose >= 11.1 mmol/L, antidiabetic medication use, or a physician diagnosis of type 2 diabetes
range:[10.0,15.0];unit:years
null
null
null
ARIC|MESA|FHS|InterAct
Partial overlap with discovery GWAS
PSS000237
PGS000133
33,694
110
33,584
46
mean:57.9;sd:20.0;unit:years
European
null
USA
null
Schizophrenia case subjects had two or more ICD codes included in phecode 295.1
null
null
null
null
BioVU
Vanderbilt University Medical Center (VUMC) biobank (BioVU)
PSS000238
PGS000133
33,694
451
33,243
46
mean:57.9;sd:20.0;unit:years
European
null
USA
null
Psychosis case subjects were identified with phecode 295
null
null
null
null
BioVU
Vanderbilt University Medical Center (VUMC) biobank (BioVU)
PSS000239
PGS000134
44,436
211
44,225
41
mean:60.2;sd:16.9;unit:years
European
null
USA
null
Schizophrenia case subjects had two or more ICD codes included in phecode 295.1
null
null
null
null
MyCode
Geisinger Health System (GHS)
PSS000240
PGS000134
44,436
499
43,937
41
mean:60.2;sd:16.9;unit:years
European
null
USA
null
Psychosis case subjects were identified with phecode 295
null
null
null
null
MyCode
Geisinger Health System (GHS)
PSS000241
PGS000135
9,569
53
9,516
48
mean:57.2;sd:19.8;unit:years
European
null
USA
null
Schizophrenia case subjects had two or more ICD codes included in phecode 295.1
null
null
null
null
BioMe
BioMe Biobank at the Mount Sinai School of Medicine (MSSM)
PSS000243
PGS000136
18,461
148
18,313
46
mean:58.5;sd:16.4;unit:years
European
null
USA
null
Schizophrenia case subjects had two or more ICD codes included in phecode 295.1
null
null
null
null
PHB
Partners HealthCare System (PHS) biobank
PSS000244
PGS000136
18,461
385
18,076
46
mean:58.5;sd:16.4;unit:years
European
null
USA
null
Psychosis case subjects were identified with phecode 295
null
null
null
null
PHB
Partners HealthCare System (PHS) biobank
PSS000245
PGS000137
1,795
74
1,721
43
mean:64.02;sd:8.24;unit:years
European
null
Austalia
null
null
null
null
null
null
BMES
null
PSS000246
PGS000137
965
72
893
null
null
European
null
UK
null
MYOC p.Gln368Ter (rs74315329) carriers using imputation. Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with y...
null
null
null
null
UKB
null
PSS000247
PGS000137
3,112
112
3,000
null
null
European
null
UK
null
ICD-10 defined Primary open-angle glaucoma (POAG)
null
null
null
null
UKB
null
PSS000248
PGS000137
3,112
112
3,000
null
null
European
null
UK
null
Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with your eyes?’; or (iii) responded ‘glaucoma’ to the question...
null
null
null
null
UKB
null
PSS000249
PGS000137
7,033
192
6,841
null
null
South Asian
null
UK
null
Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with your eyes?’; or (iii) responded ‘glaucoma’ to the question...
null
null
null
null
UKB
null
PSS000250
PGS000138, PGS000139, PGS000140, PGS000141, PGS000142, PGS000143, PGS000144, PGS000145
36,709
14,696
22,013
null
null
European
null
Australia, Denmark, Europe, Germany, Netherlands, Scotland, Sweden, Switzerland, UK, USA
null
null
null
null
29,700,475
null
BOMA|CoLaus|Edinburgh|GenPOD|GenRED|i2b2|MARS|MPIP|NESDA|QIMR|RADIANT|RS|SHIP|STAR*D|TwinGene
Part of PGC29 (PMID: 29700475)
PSS000251
PGS000146
4,886
1,026
3,860
0
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the distal colon confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000252
PGS000146
3,269
827
2,442
100
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the distal colon confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000253
PGS000146
5,530
1,670
3,860
0
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the proximal colon confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000254
PGS000146
3,292
850
2,442
100
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the proximal colon confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000255
PGS000146
4,573
713
3,860
0
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the rectum confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000256
PGS000146
3,167
725
2,442
100
null
European
null
USA, Germany
null
Colorectal adenocarcinoma located in the rectum confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000257
PGS000146
733
380
353
0
null
European
null
USA
null
Colorectal adenocarcinoma confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000258
PGS000146
1,002
486
516
100
null
European
null
USA
null
Colorectal adenocarcinoma confirmed by medical records, pathology reports, or death certificate
null
null
null
null
DALS|HPFS|NHS|VITAL|WHI|DACHS
Training and test split not relevant to PGS
PSS000259
PGS000147
4,080
1,336
2,744
57.205882
range:[25.0,90.0];unit:years
European
Spanish
Spain
null
null
null
null
2,561,368
null
MCC-Spain
null
PSS000260
PGS000148
5,500
2,568
2,932
0
mean (cases):68.8;sd (cases):9.7;unit:years
European
null
USA, Germany, Australia, Israel, Canada
null
null
null
null
null
null
Hawaiian_Colo2&3|DALS|HPFS|KCCS|MCCS|MEC|MECC|NFCCR|NHS|PLCO|VITAL|WHI|CPSII|DACHS
null
PSS000261
PGS000148
4,666
2,307
2,359
100
mean (cases):67.8;sd (cases):9.7;unit:years
European
null
USA, Germany, Australia, Israel, Canada
null
null
null
null
null
null
Hawaiian_Colo2&3|DALS|HPFS|KCCS|MCCS|MEC|MECC|NFCCR|NHS|PLCO|VITAL|WHI|DACHS|CPSII
null
PSS000262
PGS000149
361,543
1,623
359,920
45
mean:57.0;iqr:[50.0,63.0];unit:years
European
null
UK
null
Excluding participants with prevalent cancer at recruitment colorectal cancer was defined as ICD codes: C18 (except C18.1, Appendix), C19 and C20
null
null
null
null
UKB
Follow-up time = 1,751,445 person years
PSS000263
PGS000149
286,877
1,294
285,583
46
mean:57.0;iqr:[50.0,63.0];unit:years
European
null
UK
null
Excluding participants with prevalent cancer at recruitment colorectal cancer was defined as ICD codes: C18 (except C18.1, Appendix), C19 and C20
null
null
null
null
UKB
Follow-up time = 1,388,191 person years
PSS000268
PGS000150
1,043
294
749
61.744966
range:[50.0,79.0];unit:years
European
null
Germany
null
Unselected participants of the German screening colonoscopy program are recruited by gastroenterology practices in southern Germany in this multicenter study.Colonoscopy and histology reports are collected and information from these reports is extracted independently in a standardized way by two trained investigators, ...
null
null
null
null
BLITZ
null
PSS000269
PGS000150
749
249
500
60.480641
range:[50.0,79.0];unit:years
European
null
Germany
null
Unselected participants of the German screening colonoscopy program are recruited by gastroenterology practices in southern Germany in this multicenter study.Colonoscopy and histology reports are collected and information from these reports is extracted independently in a standardized way by two trained investigators, ...
null
null
null
null
BLITZ
null
PSS000271
PGS000151
3,523
1,316
2,207
40.84587
mean (cases):58.34;sd (cases):12.85;unit:years
East Asian
Han Chinese
China
null
null
null
null
null
null
NCRCC
null
PSS000272
PGS000152
343
343
0
null
mean:69.0;sd:10.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000272
PGS000152
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000273
PGS000153
827
827
0
0
mean:60.0;sd:13.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000273
PGS000153
7,020
0
7,020
0
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000274
PGS000154
387
387
0
null
mean:68.0;sd:13.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000274
PGS000154
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000275
PGS000155
992
992
0
null
mean:52.0;sd:16.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000275
PGS000155
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000276
PGS000156
908
908
0
null
mean:67.0;sd:9.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000276
PGS000156
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000277
PGS000157
450
450
0
null
mean:59.0;sd:16.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000277
PGS000157
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000278
PGS000158
531
531
0
0
mean:60.0;sd:12.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000278
PGS000158
7,020
0
7,020
0
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000279
PGS000159
163
163
0
null
mean:66.0;sd:11.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000279
PGS000159
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000280
PGS000160
421
421
0
100
mean:62.0;sd:7.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000280
PGS000160
6,407
0
6,407
100
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000281
PGS000161
453
453
0
null
mean:62.0;sd:12.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000281
PGS000161
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000282
PGS000162
387
387
0
null
mean:49.0;sd:16.0;unit:years
European
null
USA
null
Primary tumor samples from TCGA
null
null
null
null
TCGA
null
PSS000282
PGS000162
13,427
0
13,427
null
null
European
null
USA
null
null
null
null
null
null
eMERGE
null
PSS000283
PGS000011
7,814
1,230
6,584
45
mean:54.0;sd:5.7;unit:years
European
null
USA
null
Composite endpoint of either: myocardial infarction, coronary revascularization, death from coronary causes.
mean:18.8;unit:years
null
2,646,917
null
ARIC
null
PSS000284
PGS000011
4,260
null
null
44
mean:69.1;sd:6.0;unit:years
European
null
USA
null
Cross-sectional analysis of baseline scores for coronary artery calcification (Agatston score)
null
null
25,790,876
null
BioImage
null
PSS000285
PGS000011
22,389
2,902
19,487
38
mean:58.0;sd:7.7;unit:years
European
null
Sweden
null
Composite endpoint of either: myocardial infarction, coronary revascularization, death from coronary causes.
mean:19.4;unit:years
null
8,429,286
null
MDC-CC
null
PSS000286
PGS000011
21,222
971
20,251
0
mean:54.2;sd:7.1;unit:years
European
null
USA
null
Composite endpoint of either: myocardial infarction, coronary revascularization, death from coronary causes.
mean:20.5;unit:years
null
18,070,814
null
WGHS
null
PSS000287
PGS000018
1,319
null
null
69.3
mean:68.8;sd:9.3;unit:years
European
Dutch
Netherlands
null
(i) Secondary cardiovascular events (sCVE; incl myocardial infarction, stroke, ruptured abdominal aortic aneurysm, fatal cardiac failure, percuteneous of bypass surgery, leg amputation due to cardiovascular causes, cardiovascular death), (ii) atherosclerotic carotid plaque characteristics
mean:3.0;unit:years
null
15,678,794
null
AEGS1
null
PSS000290
PGS000163, PGS000165, PGS000167, PGS000168, PGS000172, PGS000174, PGS000175, PGS000176, PGS000177, PGS000179, PGS000182, PGS000186, PGS000187, PGS000188, PGS000191
2,314
null
null
null
null
European
French Canadian
Canada
null
null
null
null
null
null
CARTaGENE
null
PSS000291
PGS000163, PGS000164, PGS000165, PGS000166, PGS000167, PGS000168, PGS000169, PGS000170, PGS000171, PGS000172, PGS000173, PGS000174, PGS000175, PGS000176, PGS000177, PGS000178, PGS000179, PGS000182, PGS000183, PGS000184, PGS000185, PGS000186, PGS000187, PGS000188, PGS000189, PGS000190, PGS000191
39,260
null
null
null
null
European
null
UK
null
null
null
null
null
null
INTERVAL
null
PSS000292
PGS000192
4,232
238
3,994
null
null
European
null
Sweden
null
Composite end point of cardiovascular events was defined as myocardial infarction, ischemic stroke, and death from coronary heart disease. Death from coronary heart disease was defined on the basis of codes 412 and 414 (ICD-9) or I22–I23 and I25 (ICD-10) in the Swedish Cause of Death Register. Myocardial infarction was...
median:10.6;unit:years
null
null
null
MDC
null
PSS000294
PGS000193
92,957
29,475
63,482
45
range:[46.0,80.0];unit:years
European
null
U.K.
null
Participants completed an online follow-up questionnaire assessing common mental health disorders, including MDD symptoms. Phenotypes were derived from this questionnaire. Individuals with probable MDD met lifetime criteria based on their responses to questions derived from the Composite International Diagnostic Interv...
null
null
31,969,693
null
UKB
null
PSS000310
PGS000199
245
32
213
32
null
European
null
USA
null
Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:8.0;unit:years
null
null
null
PHB
null
PSS000311
PGS000199
243
22
221
32
null
European
null
USA
null
Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:7.0;unit:years
null
null
null
PHB
null
PSS000312
PGS000198
245
30
215
32
null
European
null
USA
null
Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:8.0;unit:years
null
null
null
PHB
null
PSS000313
PGS000198
243
22
221
32
null
European
null
USA
null
Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:7.0;unit:years
null
null
null
PHB
null
PSS000314
PGS000194, PGS000195
245
90
155
32
null
European
null
USA
null
Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:8.0;unit:years
null
null
null
PHB
null
PSS000315
PGS000194, PGS000195
243
115
128
32
null
European
null
USA
null
Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:7.0;unit:years
null
null
null
PHB
null
PSS000316
PGS000197
245
31
214
32
null
European
null
USA
null
Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases
median:8.0;unit:years
null
null
null
PHB
null