PGS Sample Set (PSS)
large_stringlengths
9
9
Polygenic Score (PGS) ID
large_stringlengths
9
2.77k
Number of Individuals
int64
1
5.33M
Number of Cases
float64
0
389k
Number of Controls
float64
0
1.14M
Percent of Participants Who are Male
float64
0
100
Sample Age
large_stringclasses
733 values
Broad Ancestry Category
large_stringclasses
73 values
Ancestry (e.g. French, Chinese)
large_stringclasses
90 values
Country of Recruitment
large_stringclasses
140 values
Additional Ancestry Description
large_stringclasses
131 values
Phenotype Definitions and Methods
large_stringclasses
798 values
Followup Time
large_stringclasses
141 values
GWAS Catalog Study ID (GCST...)
large_stringclasses
8 values
Source PubMed ID (PMID)
float64
1.25M
39.9M
Source DOI
large_stringclasses
13 values
Cohort(s)
large_stringclasses
460 values
Additional Sample/Cohort Information
large_stringclasses
245 values
PSS000529
PGS000006
2,088
297
1,791
0
null
European
null
UK, netherlands, France, Canada, Denmark, Sweden, Australia, New zealand, and more.
null
Eligibility was restricted to female BRCA1 and BRCA2 carriers who at completion of the baseline questionnaire were free of any cancer diagnosis (excluding non-melanoma skin cancer) and had not undergone risk-reducing bilateral mastectomy. Participants diagosed with a first breast cancer were considered affected.
null
null
null
null
DEMOKRITOS|BCFR-NY|BCFR-PA|BCFR-UTAH|GC-HBOC|HEBCS|MSKCC|NC-BCFR|OFBCR|UCSF|MDACCS|CNIO|DKFZ|FCCC|G-FaST|IOVHBOCS|kConFab|MAYO|NCI|UPITT|BCFR|SWE-BRCA|BCFR-AU|DFCI|EMBRACE|GEMO|HEBON|BFBOCC|BMBSA|BRICOH|CopBCS|COH|CONSIT_TEAM|Georgetown|HCSC|HUNBOCS|HUVH|ICO|IHCC|LUHR|INHERIT|KUMC|MCGILL|MUV|NNPIO|NSUHS|NRG_ONCOLOGY|OC...
null
PSS000530
PGS000352
3,152
108
3,044
0
null
European
null
UK, netherlands, France, Canada, Denmark, Sweden, Australia, New zealand, and more.
null
To assess associationss between the PRS and ovarian cancer risk, eligibility was restricted to women who had not been diagnosed with ovarian cancer and had not had RRSO at the time of baselinne questionnaire completion. Carriers diagnosed with invasive ovarian, fallopian tube, or peritoneal cancer during the follow-up ...
null
null
null
null
DEMOKRITOS|BCFR-NY|BCFR-PA|BCFR-UTAH|GC-HBOC|HEBCS|MSKCC|NC-BCFR|OFBCR|UCSF|MDACCS|CNIO|DKFZ|FCCC|G-FaST|IOVHBOCS|kConFab|MAYO|NCI|UPITT|BCFR|SWE-BRCA|BCFR-AU|DFCI|EMBRACE|GEMO|HEBON|BFBOCC|BMBSA|BRICOH|CopBCS|COH|CONSIT_TEAM|Georgetown|HCSC|HUNBOCS|HUVH|ICO|IHCC|LUHR|INHERIT|KUMC|MCGILL|MUV|NNPIO|NSUHS|NRG_ONCOLOGY|OC...
null
PSS000531
PGS000004
1,757
215
1,542
0
null
European
null
UK, netherlands, France, Canada, Denmark, Sweden, Australia, New zealand, and more.
null
Eligibility was restricted to female BRCA1 and BRCA2 carriers who at completion of the baseline questionnaire were free of any cancer diagnosis (excluding non-melanoma skin cancer) and had not undergone risk-reducing bilateral mastectomy. Participants diagosed with a first breast cancer were considered affected.
null
null
null
null
DEMOKRITOS|BCFR-NY|BCFR-PA|BCFR-UTAH|GC-HBOC|HEBCS|MSKCC|NC-BCFR|OFBCR|UCSF|MDACCS|CNIO|DKFZ|FCCC|G-FaST|IOVHBOCS|kConFab|MAYO|NCI|UPITT|BCFR|SWE-BRCA|BCFR-AU|DFCI|EMBRACE|GEMO|HEBON|BFBOCC|BMBSA|BRICOH|CopBCS|COH|CONSIT_TEAM|Georgetown|HCSC|HUNBOCS|HUVH|ICO|IHCC|LUHR|INHERIT|KUMC|MCGILL|MUV|NNPIO|NSUHS|NRG_ONCOLOGY|OC...
null
PSS000532
PGS000352
2,495
56
2,439
0
null
European
null
UK, netherlands, France, Canada, Denmark, Sweden, Australia, New zealand, and more.
null
To assess associationss between the PRS and ovarian cancer risk, eligibility was restricted to women who had not been diagnosed with ovarian cancer and had not had RRSO at the time of baseline questionnaire completion. Carriers diagnosed with invasive ovarian, fallopian tbe, or peritoneal cancer during the follow-up we...
null
null
null
null
DEMOKRITOS|BCFR-NY|BCFR-PA|BCFR-UTAH|GC-HBOC|HEBCS|MSKCC|NC-BCFR|OFBCR|UCSF|MDACCS|CNIO|DKFZ|FCCC|G-FaST|IOVHBOCS|kConFab|MAYO|NCI|UPITT|BCFR|SWE-BRCA|BCFR-AU|DFCI|EMBRACE|GEMO|HEBON|BFBOCC|BMBSA|BRICOH|CopBCS|COH|CONSIT_TEAM|Georgetown|HCSC|HUNBOCS|HUVH|ICO|IHCC|LUHR|INHERIT|KUMC|MCGILL|MUV|NNPIO|NSUHS|NRG_ONCOLOGY|OC...
null
PSS000533
PGS000353, PGS000354, PGS000355, PGS000356
15,286
10,394
4,892
null
null
European
null
USA
null
Any Cancer PheCode
null
null
32,991,828
null
MGI
null
PSS000534
PGS000359
2,841
259
2,582
null
null
European
null
USA
null
PheCode:145.2; ICD9CM:141.0, 141.1, 141.2, 141.3, 141.4, 141.5, 141.6, 141.8, 141.9, V10.01; ICD10CM:C01, C02, C02.0, C02.1, C02.2, C02.3, C02.4, C02.8, C02.9
null
null
32,991,828
null
MGI
null
PSS000535
PGS000357, PGS000358
6,328
578
5,750
null
null
European
null
USA
null
PheCode:145; ICD9CM:140.0, 140.1, 140.3, 140.4, 140.5, 140.6, 140.8, 140.9, 141.0, 141.1, 141.2, 141.3, 141.4, 141.5, 141.6, 141.8, 141.9, 142.0, 142.1, 142.2, 142.8, 142.9, 143.0, 143.1, 143.8, 143.9, 144.0, 144.1, 144.8, 144.9, 145.0, 145.1, 145.2, 145.3, 145.4, 145.5, 145.6, 145.8, 145.9, 230.0, V10.01; ICD10CM:C00,...
null
null
32,991,828
null
MGI
null
PSS000536
PGS000360, PGS000361, PGS000362
1,738
158
1,580
null
null
European
null
USA
null
PheCode:149.4; ICD9CM:161.0, 161.1, 161.2, 161.3, 161.8, 161.9, 231.0, V10.21; ICD10CM:C32, C32.0, C32.1, C32.2, C32.3, C32.8, C32.9, D02.0
null
null
32,991,828
null
MGI
null
PSS000537
PGS000363, PGS000364, PGS000365, PGS000366
2,064
188
1,876
null
null
European
null
USA
null
PheCode:150; ICD9CM:150.0, 150.1, 150.2, 150.3, 150.4, 150.5, 150.8, 150.9, 230.1, V10.03; ICD10CM:C15, C15.3, C15.4, C15.5, C15.8, C15.9, D00.1
null
null
32,991,828
null
MGI
null
PSS000538
PGS000376, PGS000377, PGS000378, PGS000379, PGS000380, PGS000381, PGS000382
5,031
462
4,569
null
null
European
null
USA
null
PheCode:153.2; ICD9CM:153.0, 153.1, 153.2, 153.3, 153.4, 153.5, 153.6, 153.7, 153.8, 153.9, 159.0, 209.10, 209.11, 209.12, 209.13, 209.14, 209.15, 209.16, 230.3, V10.05; ICD10CM:C18, C18.0, C18.1, C18.2, C18.3, C18.4, C18.5, C18.6, C18.7, C18.8, C18.9, C26.0, C7A.020, C7A.021, C7A.022, C7A.023, C7A.024, C7A.025, C7A.02...
null
null
32,991,828
null
MGI
null
PSS000539
PGS000383, PGS000384
3,557
325
3,232
null
null
European
null
USA
null
PheCode:153.3; ICD9CM:154.0, 154.1, 154.2, 154.3, 209.17, 230.4, 230.5, 230.6, 796.70, 796.71, 796.72, 796.73, 796.74, 796.76, V10.06; ICD10CM:C19, C20, C21.0, C21.1, C7A.026, D01.1, D01.2, D01.3, R85.610, R85.611, R85.612, R85.613, R85.614, R85.619
null
null
32,991,828
null
MGI
null
PSS000540
PGS000367, PGS000369, PGS000373, PGS000374, PGS000375
6,633
607
6,026
null
null
European
null
USA
null
PheCode:153; ICD9CM:153.0, 153.1, 153.2, 153.3, 153.4, 153.5, 153.6, 153.7, 153.8, 153.9, 154.0, 154.1, 154.2, 154.3, 154.8, 159.0, 209.10, 209.11, 209.12, 209.13, 209.14, 209.15, 209.16, 209.17, 230.3, 230.4, 230.5, 230.6, 796.70, 796.71, 796.72, 796.73, 796.74, 796.76, V10.05, V10.06; ICD10CM:C18, C18.0, C18.1, C18.2...
null
null
32,991,828
null
MGI
null
PSS000541
PGS000388, PGS000389, PGS000391, PGS000393, PGS000394, PGS000395, PGS000396, PGS000397
4,698
428
4,270
null
null
European
null
USA
null
PheCode:165.1; ICD9CM:162.0, 162.2, 162.3, 162.4, 162.5, 162.8, 162.9, 209.21, 231.2, V10.11; ICD10CM:C33, C34, C34.0, C34.00, C34.01, C34.02, C34.1, C34.10, C34.11, C34.12, C34.2, C34.3, C34.30, C34.31, C34.32, C34.8, C34.80, C34.81, C34.82, C34.9, C34.90, C34.91, C34.92, C7A.090, D02.2, D02.20, D02.21, D02.22
null
null
32,991,828
null
MGI
null
PSS000542
PGS000387
5,218
475
4,743
null
null
European
null
USA
null
PheCode:165; ICD9CM:162.0, 162.2, 162.3, 162.4, 162.5, 162.8, 162.9, 163.0, 163.1, 163.8, 163.9, 165.0, 165.8, 165.9, 209.21, 231.1, 231.2, 231.8, 231.9, V10.11, V10.12, V10.20, V10.29; ICD10CM:C33, C34, C34.0, C34.00, C34.01, C34.02, C34.1, C34.10, C34.11, C34.12, C34.2, C34.3, C34.30, C34.31, C34.32, C34.8, C34.80, C...
null
null
32,991,828
null
MGI
null
PSS000543
PGS000408, PGS000409, PGS000410, PGS000411, PGS000412, PGS000413, PGS000414, PGS000415, PGS000416, PGS000417, PGS000418, PGS000419, PGS000420, PGS000421, PGS000423, PGS000425, PGS000427, PGS000429, PGS000430, PGS000431, PGS000432
11,974
1,325
10,649
null
null
European
null
USA
null
PheCode:172.1; ICD9CM:172.0, 172.1, 172.2, 172.3, 172.4, 172.5, 172.6, 172.7, 172.8, 172.9, V10.82; ICD10CM:C43, C43.0, C43.1, C43.10, C43.11, C43.12, C43.2, C43.20, C43.21, C43.22, C43.3, C43.30, C43.31, C43.39, C43.4, C43.5, C43.51, C43.52, C43.59, C43.6, C43.60, C43.61, C43.62, C43.7, C43.70, C43.71, C43.72, C43.8, ...
null
null
32,991,828
null
MGI
null
PSS000544
PGS000445, PGS000446, PGS000447, PGS000448, PGS000449, PGS000450, PGS000451, PGS000452, PGS000454, PGS000456, PGS000458
11,322
1,481
9,841
null
null
European
null
USA
null
PheCode:172.21; ICD9CM:173.01, 173.11, 173.21, 173.31, 173.41, 173.51, 173.61, 173.71, 173.81, 173.91; ICD10CM:C44.01, C44.111, C44.112, C44.119, C44.211, C44.212, C44.219, C44.310, C44.311, C44.319, C44.41, C44.510, C44.511, C44.519, C44.611, C44.612, C44.619, C44.711, C44.712, C44.719, C44.81, C44.91
null
null
32,991,828
null
MGI
null
PSS000545
PGS000460, PGS000461, PGS000463, PGS000465, PGS000467
8,473
982
7,491
null
null
European
null
USA
null
PheCode:172.22; ICD9CM:173.02, 173.12, 173.22, 173.32, 173.42, 173.52, 173.62, 173.72, 173.82, 173.92; ICD10CM:C44.02, C44.121, C44.122, C44.129, C44.221, C44.222, C44.229, C44.320, C44.321, C44.329, C44.42, C44.520, C44.521, C44.529, C44.621, C44.622, C44.629, C44.721, C44.722, C44.729, C44.82, C44.92
null
null
32,991,828
null
MGI
null
PSS000546
PGS000433, PGS000434, PGS000435, PGS000436, PGS000437, PGS000438, PGS000439, PGS000440, PGS000441, PGS000442, PGS000443, PGS000444
15,898
2,954
12,944
null
null
European
null
USA
null
PheCode:172.2; ICD9CM:173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70, 173.71, 173.72, 173.79, 173.80, 173.81, 173.82, 173.89, 173.90, 17...
null
null
32,991,828
null
MGI
null
PSS000547
PGS000469, PGS000470, PGS000471
5,500
585
4,915
null
null
European
null
USA
null
PheCode:172.3; ICD9CM:232.0, 232.1, 232.2, 232.3, 232.4, 232.5, 232.6, 232.7, 232.8, 232.9; ICD10CM:D04, D04.0, D04.1, D04.10, D04.11, D04.12, D04.2, D04.20, D04.21, D04.22, D04.3, D04.30, D04.39, D04.4, D04.5, D04.6, D04.60, D04.61, D04.62, D04.7, D04.70, D04.71, D04.72, D04.8, D04.9
null
null
32,991,828
null
MGI
null
PSS000548
PGS000398, PGS000399, PGS000400, PGS000401, PGS000402, PGS000403, PGS000404, PGS000405, PGS000406, PGS000407
17,607
3,557
14,050
null
null
European
null
USA
null
PheCode:172; ICD9CM:172.0, 172.1, 172.2, 172.3, 172.4, 172.5, 172.6, 172.7, 172.8, 172.9, 173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70...
null
null
32,991,828
null
MGI
null
PSS000549
PGS000472, PGS000473, PGS000474, PGS000475, PGS000476, PGS000477, PGS000478, PGS000479, PGS000480, PGS000481, PGS000482, PGS000483, PGS000484, PGS000485, PGS000487, PGS000489, PGS000491, PGS000493, PGS000495, PGS000497, PGS000499, PGS000501, PGS000503, PGS000505, PGS000507, PGS000509, PGS000511, PGS000513, PGS000514, P...
7,785
1,341
6,444
null
null
European
null
USA
null
PheCode:174.1; ICD9CM:174.0, 174.1, 174.2, 174.3, 174.4, 174.5, 174.6, 174.8, 174.9, 233.0, V10.3; ICD10CM:C50, C50.0, C50.01, C50.011, C50.012, C50.019, C50.02, C50.021, C50.022, C50.029, C50.1, C50.11, C50.111, C50.112, C50.119, C50.12, C50.121, C50.122, C50.129, C50.2, C50.21, C50.211, C50.212, C50.219, C50.22, C50....
null
null
32,991,828
null
MGI
null
PSS000550
PGS000559, PGS000561
1,904
174
1,730
null
null
European
null
USA
null
PheCode:184.11; ICD9CM:183.0, V10.43; ICD10CM:C56, C56.1, C56.2, C56.9
null
null
32,991,828
null
MGI
null
PSS000551
PGS000543
4,905
453
4,452
null
null
European
null
USA
null
PheCode:184; ICD9CM:181, 183.0, 183.2, 183.3, 183.4, 183.5, 183.8, 183.9, 184.0, 184.1, 184.2, 184.3, 184.4, 184.8, 184.9, 233.30, 233.31, 233.32, 233.39, 236.0, 236.1, 236.2, 236.3, V10.40, V10.43, V10.44; ICD10CM:C51, C51.0, C51.1, C51.2, C51.8, C51.9, C52, C56, C56.1, C56.2, C56.9, C57, C57.0, C57.00, C57.01, C57.02...
null
null
32,991,828
null
MGI
null
PSS000552
PGS000565, PGS000566, PGS000567, PGS000568, PGS000569, PGS000570, PGS000571, PGS000572, PGS000573, PGS000574, PGS000575, PGS000576, PGS000577, PGS000579, PGS000581, PGS000583, PGS000585, PGS000587, PGS000589, PGS000590, PGS000591, PGS000592
5,607
1,190
4,417
null
null
European
null
USA
null
PheCode:185; ICD9CM:185, 233.4, V10.46; ICD10CM:C61, D07.5
null
null
32,991,828
null
MGI
null
PSS000553
PGS000595, PGS000596, PGS000597, PGS000598, PGS000599, PGS000600, PGS000601, PGS000603
755
73
682
null
null
European
null
USA
null
PheCode:187.2; ICD9CM:186.0, 186.9, V10.47; ICD10CM:C62, C62.0, C62.00, C62.01, C62.02, C62.1, C62.10, C62.11, C62.12, C62.9, C62.90, C62.91, C62.92
null
null
32,991,828
null
MGI
null
PSS000554
PGS000593, PGS000594
1,490
137
1,353
null
null
European
null
USA
null
PheCode:187; ICD9CM:186.0, 186.9, 187.1, 187.2, 187.3, 187.4, 187.5, 187.6, 187.7, 187.8, 187.9, 233.5, 233.6, 236.4, 236.5, 236.6, V10.45, V10.47, V10.48, V10.49; ICD10CM:C60, C60.0, C60.1, C60.2, C60.8, C60.9, C62, C62.0, C62.00, C62.01, C62.02, C62.1, C62.10, C62.11, C62.12, C62.9, C62.90, C62.91, C62.92, C63, C63.0...
null
null
32,991,828
null
MGI
null
PSS000555
PGS000607, PGS000608, PGS000609, PGS000610, PGS000612, PGS000614, PGS000615, PGS000616
7,622
789
6,833
null
null
European
null
USA
null
PheCode:189.2; ICD9CM:188.0, 188.1, 188.2, 188.3, 188.4, 188.5, 188.6, 188.7, 188.8, 188.9, 233.7, 236.7, 239.4, V10.51; ICD10CM:C67, C67.0, C67.1, C67.2, C67.3, C67.4, C67.5, C67.6, C67.7, C67.8, C67.9, D09.0, D41.4, D49.4
null
null
32,991,828
null
MGI
null
PSS000556
PGS000617
672
62
610
null
null
European
null
USA
null
PheCode:190; ICD9CM:190.0, 190.1, 190.2, 190.3, 190.4, 190.5, 190.6, 190.7, 190.8, 190.9, 234.0, V10.84; ICD10CM:C69, C69.0, C69.00, C69.01, C69.02, C69.1, C69.10, C69.11, C69.12, C69.2, C69.20, C69.21, C69.22, C69.3, C69.30, C69.31, C69.32, C69.4, C69.40, C69.41, C69.42, C69.5, C69.50, C69.51, C69.52, C69.6, C69.60, C...
null
null
32,991,828
null
MGI
null
PSS000557
PGS000620, PGS000621, PGS000623, PGS000625
2,563
233
2,330
null
null
European
null
USA
null
PheCode:191.11; ICD9CM:191.0, 191.1, 191.2, 191.3, 191.4, 191.5, 191.6, 191.7, 191.8, 191.9, V10.85; ICD10CM:C71, C71.0, C71.1, C71.2, C71.3, C71.4, C71.5, C71.6, C71.7, C71.8, C71.9
null
null
32,991,828
null
MGI
null
PSS000558
PGS000626, PGS000627, PGS000628, PGS000629, PGS000630, PGS000632, PGS000634, PGS000635, PGS000636
4,270
389
3,881
null
null
European
null
USA
null
PheCode:193; ICD9CM:193, V10.87; ICD10CM:C73
null
null
32,991,828
null
MGI
null
PSS000559
PGS000637, PGS000638, PGS000639, PGS000640
775
71
704
null
null
European
null
USA
null
PheCode:201; ICD9CM:201.00, 201.01, 201.02, 201.03, 201.04, 201.05, 201.06, 201.07, 201.08, 201.10, 201.11, 201.12, 201.13, 201.14, 201.15, 201.16, 201.17, 201.18, 201.20, 201.21, 201.22, 201.23, 201.24, 201.25, 201.26, 201.27, 201.28, 201.40, 201.41, 201.42, 201.43, 201.44, 201.45, 201.46, 201.47, 201.48, 201.50, 201....
null
null
32,991,828
null
MGI
null
PSS000560
PGS000643, PGS000644
3,256
296
2,960
null
null
European
null
USA
null
PheCode:202.21; ICD9CM:202.00, 202.01, 202.02, 202.03, 202.04, 202.05, 202.06, 202.07, 202.08; ICD10CM:C82, C82.0, C82.00, C82.01, C82.02, C82.03, C82.04, C82.05, C82.06, C82.07, C82.08, C82.09, C82.1, C82.10, C82.11, C82.12, C82.13, C82.14, C82.15, C82.16, C82.17, C82.18, C82.19, C82.2, C82.20, C82.21, C82.22, C82.23,...
null
null
32,991,828
null
MGI
null
PSS000561
PGS000646, PGS000648, PGS000650, PGS000651
756
69
687
null
null
European
null
USA
null
PheCode:204.12; ICD9CM:204.10, 204.11, 204.12; ICD10CM:C91.1, C91.10, C91.11, C91.12
null
null
32,991,828
null
MGI
null
PSS000562
PGS000645
957
87
870
null
null
European
null
USA
null
PheCode:204.1; ICD9CM:204.00, 204.01, 204.02, 204.10, 204.11, 204.12, 204.20, 204.21, 204.22, 204.80, 204.81, 204.82, 204.90, 204.91, 204.92, V10.61; ICD10CM:C91, C91.0, C91.00, C91.01, C91.02, C91.1, C91.10, C91.11, C91.12, C91.3, C91.30, C91.31, C91.32, C91.4, C91.40, C91.41, C91.42, C91.5, C91.50, C91.51, C91.52, C9...
null
null
32,991,828
null
MGI
null
PSS000563
PGS000652
908
83
825
null
null
European
null
USA
null
PheCode:204.4; ICD9CM:203.00, 203.01, 203.02, 203.80, 203.81, 203.82; ICD10CM:C88.2, C88.3, C88.9, C90.0, C90.00, C90.01, C90.02, C90.2, C90.20, C90.21, C90.22, C90.30, C90.31, C90.32
null
null
32,991,828
null
MGI
null
PSS000564
PGS000368, PGS000370, PGS000371, PGS000372
24,996
2,271
22,725
null
null
European
null
UK
null
PheCode:153; ICD9:154.8; ICD10:C18.0, C18.1, C18.2, C18.3, C18.4, C18.5, C18.6, C18.7, C18.8, C18.9, C19, C20, C21.0, C21.1, C21.8, C26.0, D01.0, D01.1, D01.2, D01.3
null
null
32,991,828
null
UKB
null
PSS000565
PGS000385, PGS000386
3,591
327
3,264
null
null
European
null
UK
null
PheCode:157; ICD9:157, 157.0, 157.1, 157.2, 157.3, 157.4, 157.8, 157.9; ICD10:C25.0, C25.1, C25.2, C25.3, C25.4, C25.7, C25.8, C25.9
null
null
32,991,828
null
UKB
null
PSS000566
PGS000390, PGS000392
12,201
1,109
11,092
null
null
European
null
UK
null
PheCode:165.1; ICD9:162, 162.0, 162.2, 162.3, 162.4, 162.5, 162.8, 162.9, 231.2; ICD10:C33, C34.0, C34.1, C34.2, C34.3, C34.8, C34.9, D02.2
null
null
32,991,828
null
UKB
null
PSS000567
PGS000422, PGS000424, PGS000426, PGS000428
14,482
1,317
13,165
null
null
European
null
UK
null
PheCode:172.1; ICD9:-; ICD10:C43.0, C43.1, C43.2, C43.3, C43.4, C43.5, C43.6, C43.7, C43.8, C43.9, D03.0, D03.1, D03.2, D03.3, D03.4, D03.5, D03.6, D03.7, D03.8, D03.9
null
null
32,991,828
null
UKB
null
PSS000568
PGS000453, PGS000455, PGS000457, PGS000459
60,018
5,450
54,568
null
null
European
null
UK
null
PheCode:172.21; ICD9:173, 173.0, 173.1, 173.2, 173.3, 173.4, 173.5, 173.6, 173.7, 173.8, 173.9; ICD10:C44.0, C44.1, C44.2, C44.3, C44.4, C44.5, C44.6, C44.7, C44.8, C44.9
null
null
32,991,828
null
UKB
null
PSS000569
PGS000462, PGS000464, PGS000466, PGS000468
60,018
5,450
54,568
null
null
European
null
UK
null
PheCode:172.22; ICD9:173, 173.0, 173.1, 173.2, 173.3, 173.4, 173.5, 173.6, 173.7, 173.8, 173.9; ICD10:C44.0, C44.1, C44.2, C44.3, C44.4, C44.5, C44.6, C44.7, C44.8, C44.9
null
null
32,991,828
null
UKB
null
PSS000570
PGS000486, PGS000488, PGS000490, PGS000492, PGS000494, PGS000496, PGS000498, PGS000500, PGS000502, PGS000504, PGS000506, PGS000508, PGS000510, PGS000512, PGS000518, PGS000520, PGS000522, PGS000524, PGS000526, PGS000528, PGS000530, PGS000532, PGS000534, PGS000536, PGS000538, PGS000540
68,531
6,242
62,289
null
null
European
null
UK
null
PheCode:174.1; ICD9:233.0; ICD10:C50.0, C50.1, C50.2, C50.3, C50.4, C50.5, C50.6, C50.8, C50.9, D05.1, D05.7, D05.9, Z85.3
null
null
32,991,828
null
UKB
null
PSS000571
PGS000541, PGS000542
6,987
634
6,353
null
null
European
null
UK
null
PheCode:182; ICD9:179, 182, 182.0, 182.1, 182.8, 233.2; ICD10:C54.0, C54.1, C54.2, C54.3, C54.8, C54.9, C55, D07.0
null
null
32,991,828
null
UKB
null
PSS000572
PGS000544, PGS000545, PGS000546, PGS000547, PGS000548, PGS000549, PGS000550, PGS000551, PGS000552, PGS000553, PGS000554, PGS000555, PGS000556, PGS000557, PGS000558, PGS000560, PGS000562, PGS000563, PGS000564
5,196
473
4,723
null
null
European
null
UK
null
PheCode:184.11; ICD9:183.0; ICD10:C56
null
null
32,991,828
null
UKB
null
PSS000573
PGS000578, PGS000580, PGS000582, PGS000584, PGS000586, PGS000588
32,664
3,012
29,652
null
null
European
null
UK
null
PheCode:185; ICD9:185, 233.4; ICD10:C61, D07.5
null
null
32,991,828
null
UKB
null
PSS000574
PGS000602, PGS000604
1,484
135
1,349
null
null
European
null
UK
null
PheCode:187.2; ICD9:186, 186.0, 186.9; ICD10:C62.0, C62.1, C62.9
null
null
32,991,828
null
UKB
null
PSS000575
PGS000605, PGS000606
5,818
529
5,289
null
null
European
null
UK
null
PheCode:189.11; ICD9:189.0; ICD10:C64
null
null
32,991,828
null
UKB
null
PSS000576
PGS000611, PGS000613
13,530
1,229
12,301
null
null
European
null
UK
null
PheCode:189.2; ICD9:233.7, 236.7, 239.4; ICD10:C67.0, C67.1, C67.2, C67.3, C67.4, C67.5, C67.6, C67.7, C67.8, C67.9, D09.0, D41.4
null
null
32,991,828
null
UKB
null
PSS000577
PGS000622, PGS000624
3,020
275
2,745
null
null
European
null
UK
null
PheCode:191.11; ICD9:191, 191.0, 191.1, 191.2, 191.3, 191.4, 191.5, 191.6, 191.7, 191.8, 191.9; ICD10:C71.0, C71.1, C71.2, C71.3, C71.4, C71.5, C71.6, C71.7, C71.8, C71.9
null
null
32,991,828
null
UKB
null
PSS000578
PGS000618, PGS000619
3,110
283
2,827
null
null
European
null
UK
null
PheCode:191.1; ICD9:192, 192.0, 192.1, 192.2, 192.3, 192.8, 192.9; ICD10:C70.0, C70.1, C70.9, C71.0, C71.1, C71.2, C71.3, C71.4, C71.5, C71.6, C71.7, C71.8, C71.9, C72.0, C72.1, C72.2, C72.3, C72.4, C72.5, C72.8, C72.9
null
null
32,991,828
null
UKB
null
PSS000579
PGS000631, PGS000633
1,778
161
1,617
null
null
European
null
UK
null
PheCode:193; ICD9:193; ICD10:C73
null
null
32,991,828
null
UKB
null
PSS000580
PGS000641, PGS000642
9,952
901
9,051
null
null
European
null
UK
null
PheCode:202.2; ICD9:200, 200.2, 200.8, 202.1, 202.2, 202.8, 202.9; ICD10:B21.1, C82.0, C82.1, C82.2, C82.7, C82.9, C83.0, C83.1, C83.2, C83.3, C83.4, C83.5, C83.6, C83.7, C83.8, C83.9, C84.0, C84.1, C84.2, C84.3, C84.4, C84.5, C85.0, C85.1, C85.7, C85.9, C96.7, C96.9, L41.2
null
null
32,991,828
null
UKB
null
PSS000581
PGS000647, PGS000649
2,758
249
2,509
null
null
European
null
UK
null
PheCode:204.12; ICD9:204.1; ICD10:C91.1
null
null
32,991,828
null
UKB
null
PSS000582
PGS000653, PGS000654
2,738
248
2,490
null
null
European
null
UK
null
PheCode:204.4; ICD9:203, 203.0, 203.8; ICD10:C88.1, C88.3, C88.9, C90.0, C90.2
null
null
32,991,828
null
UKB
null
PSS000583
PGS000655
9,677
1,106
8,571
42.6
null
European
null
USA
null
Case inclusion ICD codes: ICD9=571.5, ICD9=571.8, ICD9=571.9, ICD10=K75.81, ICD10=K76.0, ICD10=K76.9
null
null
null
null
eMERGE
null
PSS000584
PGS000655, PGS000656
235
79
156
null
null
European
null
USA
null
Controls are cases with Nonalcoholic fatty liver disease activity score <5 and cases are those with a score >5. Case inclusion ICD codes: ICD9=571.5, ICD9=571.8, ICD9=571.9, ICD10=K75.81, ICD10=K76.0, ICD10=K76.9
null
null
null
null
eMERGE
null
PSS000585
PGS000657
4,741
null
null
47.5
mean:55.8;sd:7.6;unit:years
European
null
UK
null
null
null
null
null
null
UKB
null
PSS000585
PGS000657
6,704
null
null
49.3
mean:62.6;sd:9.9;unit:years
European, NR
null
Canada
null
null
null
null
null
null
CLSA
null
PSS000585
PGS000657
3,426
null
null
0
mean:71.5;sd:5.3;unit:years
European, NR
null
USA
null
null
null
null
null
null
SOF
null
PSS000585
PGS000657
4,657
null
null
100
mean:74.0;sd:6.0;unit:years
European
null
USA
null
null
null
null
null
null
MrOS-USA
null
PSS000585
PGS000657
1,880
null
null
100
mean:75.4;sd:3.2;unit:years
European
Swedish
Sweden
null
null
null
null
null
null
MrOS-SWE
null
PSS000586
PGS000657
80,027
null
null
47.5
mean:55.8;sd:7.6;unit:years
European
null
UK
null
null
null
null
null
null
UKB
null
PSS000587
PGS000658, PGS000659, PGS000660
426
null
null
46
mean:43.3;sd:11.4;unit:years
East Asian
Chinese
Hong Kong
null
Measured using fasting blood samples
null
null
16,718,283
null
null
Adults
PSS000588
PGS000661
426
null
null
46
mean:43.3;sd:11.4;unit:years
East Asian
Chinese
Hong Kong
null
Derived from the Friedewald’s formula
null
null
16,718,283
null
null
Adults
PSS000589
PGS000658, PGS000659, PGS000660
1,941
null
null
57.7
mean:58.2;sd:12.34;unit:years
East Asian
Chinese
Hong Kong
null
Measured using fasting blood samples
null
null
32,722,720
null
HKDB
null
PSS000590
PGS000661
1,941
null
null
57.7
mean:58.2;sd:12.34;unit:years
East Asian
Chinese
Hong Kong
null
Derived from the Friedewald’s formula
null
null
32,722,720
null
HKDB
null
PSS000591
PGS000658, PGS000659, PGS000660
865
null
null
57.6
mean:57.0;sd:12.08;unit:years
East Asian
Chinese
Hong Kong
null
Measured using fasting blood samples
null
null
32,722,720
null
HKDB
null
PSS000592
PGS000661
865
null
null
57.6
mean:57.0;sd:12.08;unit:years
East Asian
Chinese
Hong Kong
null
Derived from the Friedewald’s formula
null
null
32,722,720
null
HKDB
null
PSS000593
PGS000658, PGS000659, PGS000660
4,917
null
null
44.9
mean:56.3;sd:13.5;unit:years
East Asian
Chinese
Hong Kong
null
Measured using fasting blood samples
null
null
30,415,941
null
HKDR
null
PSS000594
PGS000661
4,917
null
null
44.9
mean:56.3;sd:13.5;unit:years
East Asian
Chinese
Hong Kong
null
Derived from the Friedewald’s formula
null
null
30,415,941
null
HKDR
null
PSS000595
PGS000662
2,633
1,586
1,047
100
null
African unspecified
null
USA, Uganda
null
null
null
null
null
null
CAUG
null
PSS000596
PGS000662
199,969
6,852
193,117
100
null
European
null
UK
null
null
null
null
null
null
UKB
null
PSS000597
PGS000663
956
304
652
28.1
null
European
null
null
null
In this study, cases were incident patients with primary pancreatic adenocarcinoma ascertained between 1984 and 2010 through self- report, report of next-of-kin, or death certificates and confirmed by medical record review and tumor registry data. Cases Diagnosed within 10 years of blood collection.
mean:10.0;unit:years
null
null
null
HPFS|NHS|PHS|WHI
Overlap with GWAS samples (percentage unknown). Cross validation approach used (20% as testing sample)
PSS000598
PGS000663
1,591
500
1,091
33.4
null
European
null
null
null
In this study, cases were incident patients with primary pancreatic adenocarcinoma ascertained between 1984 and 2010 through self- report, report of next-of-kin, or death certificates and confirmed by medical record review and tumor registry data.
null
null
null
null
HPFS|NHS|PHS|WHI
Overlap with GWAS samples (percentage unknown). Cross validation approach used (20% as testing sample)
PSS000599
PGS000664
3,447
1,013
2,434
null
null
European
null
null
null
Cases: ICD 10 code N17. Controls: no ICD10 code N17, frequency-matched by age-group and sex
null
null
null
null
UKB
Possible overlap between GWAS cohorts and this dataset.
PSS000600
PGS000664
11,440
448
10,992
null
null
European
null
null
null
CKDi25 cases defined as >25% eGFRcrea decline during follow-up together with a movement from eGFRcrea≥60 mL/min/1.73m^2 at baseline to eGFR<60 mL/min/1.73m^2 at follow up compared to CKDi25 controls defined as eGFRcrea≥60 mL/min/1.73m^2. High risk groups had 8-14 adverse alleles. Low risk groups had 0-5 adverse alleles...
null
null
null
null
UKB|DIACORE|KORA
87.61% overlap between the CKDi25 GWAS cohort and this dataset.
PSS000601
PGS000665
11,187
395
10,792
60.78
mean:70.8;sd:9.1;unit:years
European
null
null
null
All patients with atrial fibrillation and CHADS2 score of 2 or higher who were treated with anticoagulation. The endpoint of interest was ischemic stroke. In each trial, ischemic stroke was formally adjudicated by an independent clinical endpoint committee blinded to treatment assignment.
median:2.8;unit:years
null
null
null
ENGAGE_AF-TIMI_48
null
PSS000602
PGS000665
51,288
960
50,328
71.7
mean:65.9;sd:9.2;unit:years
European
null
null
null
The endpoint of interest was ischemic stroke. In each trial, ischemic stroke was formally adjudicated by an independent clinical endpoint committee blinded to treatment assignment.
median:2.5;unit:years
null
null
null
ENGAGE_AF-TIMI_48|SOLID-TIMI_52|SAVOR-TIMI_53|PEGASUS-TIMI_54|FOURIER
null
PSS000603
PGS000666
449,027
923
448,104
null
null
NR
null
null
null
Hospitalization for or death due to ICD-10 code for dilated cardiomyopathy (I42.0); excluding individuals with history of coronary artery disease (as defined below), or history of hypertrophic cardiomyopathy during verbal interview with trained nurse, or hospitalization for or death due to ICD-10 code for hypertrophic ...
null
null
null
null
UKB
null
PSS000604
PGS000666
362,922
380
362,542
45
mean:57.0;sd:8.1;unit:years
European, South Asian, African unspecified, East Asian, NR
null
null
African unspecified = 2937, East Asain = 1303, European = 348778, NR = 3670, South Asian =6234
Incident DCM: Hospitalization for or death due to ICD-10 code for dilated cardiomyopathy (I42.0); excluding individuals with history of coronary artery disease (as defined below), or history of hypertrophic cardiomyopathy during verbal interview with trained nurse, or hospitalization for or death due to ICD-10 code for...
null
null
null
null
UKB
null
PSS000605
PGS000667
113,703
5,938
107,765
null
null
European
null
null
null
This subgroup included individuals with complete and imputed data and were classified as having borderline-intermediate ASCVD risk (defined by the Pooled Cohorts Equation) without prevalent ASCVD, diabetes mellitus, severe hypercholesterolemia, or use of cholesterol-lowering medication (10-year risk of 5-20%). Cases i...
median:11.1;unit:years
null
null
null
UKB
null
PSS000606
PGS000667
144,350
5,505
138,845
null
null
European
null
null
null
This subgroup included individuals with complete and imputed data and were classified as having borderline-intermediate ASCVD risk (defined by QRISK3) without prevalent ASCVD, diabetes mellitus, severe hypercholesterolemia, or use of cholesterol-lowering medication (10-year risk of 5-20%). Cases included individuals wh...
median:11.1;unit:years
null
null
null
UKB
null
PSS000607
PGS000667
283,540
7,771
275,769
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. Coronary artery disease defined as: ICD-9 (410, 411, 412, 42979), ICD-10 (I21, I22, I23, I24.1, I25.2) and OCPS-4 (K40, K41, K42, K43, K44, K45, K46, K47, K48, K49, K50 and K75)
median:11.1;unit:years
null
null
null
UKB
null
PSS000608
PGS000667
283,540
3,539
280,001
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. Cardiovascular mortality defined as: ICD-10 (any diagnosis code for causes of death related to chapter IX diseases of the circulatory system).
median:11.1;unit:years
null
null
null
UKB
null
PSS000609
PGS000667
283,540
5,666
277,874
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. Myocardial infarction defined as: ICD-9 (410, 411, 412, 42979) and ICD-10 (I21, I22, I23, I24.1, I25.2).
median:11.1;unit:years
null
null
null
UKB
null
PSS000610
PGS000667
283,540
2,283
281,257
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. Peripheral artery disease (non-coronary or cerebrovascular events) defined as: ICD-9 (440, 444, 4438, 4439), ICD-10 (I70, I74, I73.8, I73.9) and OCPS-4 (L50, L51, L52, L54, L58, L59, L60, L63, X09).
median:11.1;unit:years
null
null
null
UKB
null
PSS000611
PGS000667
283,540
14,697
268,843
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. The outcomes of myocardial infarction, coronary artery disease, ischemic stroke, peripheral arterial disease, cardiovascular mortality, and a composite of the aforementioned outcomes were based on Int...
median:11.1;unit:years
null
null
null
UKB
null
PSS000612
PGS000667
283,540
2,938
280,602
null
null
European
null
null
null
At the time of enrollment, particpants were without ASCVD. Participants were not using cholesterol-lowering medication. Ischemic stroke defined as: ICD-9 (434, 436) and ICD-10 (I63, I64)
median:11.1;unit:years
null
null
null
UKB
null
PSS000613
PGS000667
6,521
null
null
null
null
African unspecified
null
null
null
The outcomes of myocardial infarction, coronary artery disease, ischemic stroke, peripheral arterial disease, cardiovascular mortality, and a composite of the aforementioned outcomes were based on International Statistical Classification of Diseases and Related Health Problems and Office of Population Censuses and Surv...
null
null
null
null
UKB
null
PSS000614
PGS000667
2,774
null
null
null
null
East Asian
null
null
null
The outcomes of myocardial infarction, coronary artery disease, ischemic stroke, peripheral arterial disease, cardiovascular mortality, and a composite of the aforementioned outcomes were based on International Statistical Classification of Diseases and Related Health Problems and Office of Population Censuses and Surv...
null
null
null
null
UKB
null
PSS000615
PGS000667
350,903
null
null
null
null
European
null
null
null
The outcomes of myocardial infarction, coronary artery disease, ischemic stroke, peripheral arterial disease, cardiovascular mortality, and a composite of the aforementioned outcomes were based on International Statistical Classification of Diseases and Related Health Problems and Office of Population Censuses and Surv...
null
null
null
null
UKB
null
PSS000616
PGS000667
6,203
null
null
null
null
South Asian
null
null
null
The outcomes of myocardial infarction, coronary artery disease, ischemic stroke, peripheral arterial disease, cardiovascular mortality, and a composite of the aforementioned outcomes were based on International Statistical Classification of Diseases and Related Health Problems and Office of Population Censuses and Surv...
null
null
null
null
UKB
null
PSS000617
PGS000674
5,981
null
null
null
null
African unspecified
null
UK
null
null
null
null
null
null
UKB
null
PSS000618
PGS000674
1,069
null
null
null
null
East Asian
null
UK
null
null
null
null
null
null
UKB
null
PSS000619
PGS000674
23,478
null
null
null
null
European
null
UK
Non-British White
null
null
null
null
null
UKB
null
PSS000620
PGS000674
7,309
null
null
null
null
South Asian
null
UK
null
null
null
null
null
null
UKB
null
PSS000621
PGS000674
63,545
null
null
null
null
European
British
UK
null
null
null
null
null
null
UKB
null
PSS000622
PGS000668
6,017
null
null
null
null
African unspecified
null
UK
null
null
null
null
null
null
UKB
null
PSS000623
PGS000668
1,081
null
null
null
null
East Asian
null
UK
null
null
null
null
null
null
UKB
null
PSS000624
PGS000668
23,569
null
null
null
null
European
null
UK
Non-British White
null
null
null
null
null
UKB
null