protein_id stringlengths 6 10 | protein_names stringlengths 2 1.26k | protein_function stringlengths 9 5.75k ⌀ | organism stringclasses 589
values | length float64 11 16k | subcellular_location stringlengths 7 6.16k ⌀ | sequence stringlengths 11 16k | go_ids listlengths 2 494 | go_bp listlengths 0 437 ⌀ | go_mf listlengths 0 59 ⌀ | go_cc listlengths 0 67 ⌀ | structure_path stringlengths 25 29 ⌀ | string_id stringlengths 10 27 ⌀ | interaction_partners listlengths 1 668 ⌀ | interpro_ids listlengths 1 20 ⌀ | interpro_location stringlengths 3 529 | ppi_formatted stringlengths 0 811 | interpro_formatted stringlengths 0 1.79k | go_pred stringlengths 369 15k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Q8IYD1 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA. GSPT2/ERF3B mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site. GTP hydrolysis by GSPT2/... | Homo sapiens (Human) | 628 | Cytoplasm | MDSGSSSSDSAPDCWDQVDMESPGSAPSGDGVSSAVAEAQREPLSSAFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFE... | [
"GO:0006412",
"GO:0006415",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0019538",
"GO:0022411",
"GO:0032984",
"GO:0043170",
"GO:0043933",
"GO:0044238",
"GO:0071840",
"GO:0160307"
] | [
"GO:0006412",
"GO:0006415",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0019538",
"GO:0022411",
"GO:0032984",
"GO:0043170",
"GO:0043933",
"GO:0044238",
"GO:0071840",
"GO:0160307"
] | [] | [] | AF-Q8IYD1-F1-model_v6.pdb | 9606.ENSP00000341247 | [
"Q93004",
"Q86X73",
"Q9NVJ8",
"Q9UP30",
"Q96GF2",
"Q96CG1",
"Q9UE98",
"Q96RW3",
"Q92900",
"Q9H074"
] | [
"IPR000795",
"IPR009000",
"IPR009818",
"IPR050100",
"IPR027417",
"IPR031157",
"IPR009001",
"IPR004161",
"IPR054696"
] | {"IPR027417": [183, 443], "IPR009000": [425, 515], "IPR009001": [521, 624], "IPR050100": [200, 623], "IPR000795": [201, 425], "IPR004161": [443, 510], "IPR054696": [522, 620], "IPR009818": [47, 64], "IPR031157": [257, 272]} | - Eukaryotic peptide chain release factor subunit 1
- Serine/threonine-protein kinase SMG1
- Polyadenylate-binding protein 1
- Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1... | - IPR000795: Translational (tr)-type GTP-binding domain (domain) [201-425]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [425-515]
- IPR009818: PAM2 motif (conserved_site) [47-64]
- IPR050100: Translation factor GTPase superfamily members (family) [200-623]
- IPR027417: P-loo... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO... |
A0A1D8PH78 | Farnesyl pyrophosphate synthase | Farnesyl pyrophosphate synthase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 351 | null | MSDKLAARERFLDVFEDLVEELKQILVSYNMPQEAIEWFVRSLNYNTPGGKLNRGLSVVDTFAILNNTTSDKLNDTEYKKVALLGWAIELLQAYFLVADDMMDQSKTRRGQPCWYLVEGVNNIAINDSFMLEGAIYILLKKHFRQDPYYVDLLDLFHEVTFQTELGQLLDLITADEEIVDLDKFSLEKHSFIVIFKTAYYSFYLPVALAMYMSGINDEKDLKQVRDILIPLGEYFQIQDDYLDCFGTPEQIGKIGTDIKDNKCSWVINQALLIATPEQRQLLDNNYGKKDDESEQKCKDLFKQLGIEKIYHDYEESIVAK... | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-A0A1D8PH78-F1-model_v6.pdb | 237561.A0A1D8PH78 | [
"A0A1D8PLY3",
"A0A1D8PTW6",
"Q5A888",
"A0A1D8PI71",
"Q5AJZ3",
"A0A1D8PNS6",
"A0A1D8PC43",
"Q96W98",
"Q5AM05",
"Q59V08",
"G1UB11",
"A0A1D8PLI2",
"Q92208",
"Q5AD51",
"A0A1D8PFD1",
"A0A1D8PRR4",
"A0A1D8PD39",
"A0A1D8PIC7",
"A0A1D8PEL1",
"A0A1D8PLH0",
"Q92206",
"A0A1D8PH52",
... | [
"IPR000092",
"IPR033749",
"IPR039702",
"IPR008949"
] | {"IPR008949": [2, 350], "IPR039702": [7, 351], "IPR000092": [34, 349], "IPR033749": [96, 243]} | - Isopentenyl-diphosphate delta-isomerase
- Diphosphomevalonate decarboxylase
- Squalene synthase ERG9
- Farnesyltranstransferase
- Trans-hexaprenyltranstransferase
- Alkyl transferase
- Alkyl transferase
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Mevalonate kinase
- Protein farnesyl... | - IPR000092: Polyprenyl synthetase-like (family) [34-349]
- IPR033749: Polyprenyl synthetase, conserved site (conserved_site) [96-243]
- IPR039702: Farnesyl pyrophosphate synthase-like (family) [7-351]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [2-350] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004659 (prenyltransferase activity), GO:0004311 (farnesyltranstransferase activity)
Biological Proce... |
A1L1G1 | Epithelial splicing regulatory protein 1 | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory re... | Danio rerio (Zebrafish) (Brachydanio rerio) | 714 | Nucleus | MTVNPDYLVLLFTTTSGASGDKLGSDEKEIVQLVWQVVDLATKKAGQVNELLVKPDHIELSEECQELSGLTDEALTPVDPLEVAIDQLNQRLCAEVDTGAGNTFYLCTDGQLHVRQVLHPEASSKNILLPDCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNVAVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGGRYIEVYKATGEDFLKIAGGTSNEVASFL... | [
"GO:0008150",
"GO:0009653",
"GO:0032502",
"GO:0048856",
"GO:1904888",
"GO:1905748"
] | [
"GO:0008150",
"GO:0009653",
"GO:0032502",
"GO:0048856",
"GO:1904888",
"GO:1905748"
] | [] | [] | AF-A1L1G1-F1-model_v6.pdb | 7955.ENSDARP00000094207 | [
"Q5TZC8"
] | [
"IPR050666",
"IPR036397",
"IPR034427",
"IPR035979",
"IPR013520",
"IPR000504",
"IPR012337",
"IPR012677"
] | {"IPR036397": [3, 197], "IPR012337": [5, 174], "IPR012677": [215, 540], "IPR035979": [220, 532], "IPR050666": [217, 528], "IPR013520": [6, 191], "IPR034427": [216, 308], "IPR000504": [225, 526]} | - Protein enabled homolog | - IPR050666: Epithelial Splicing Regulatory (family) [217-528]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [3-197]
- IPR034427: ESRP1, RNA recognition motif 1 (domain) [216-308]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [220-532]
- IPR013520: Ribonuclease H-like domain (d... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:00... |
Q7ZVR8 | Epithelial splicing regulatory protein 2 | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory re... | Danio rerio (Zebrafish) (Brachydanio rerio) | 736 | Nucleus | MASHSDTLVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKVGKLHRTLVQPDSVDLSEQCKEETGLTAEELCKAEPLESVLQQFHQSVSAELKSLGRSSYTLCVDGPLLIRQVLHPEASKKNLVLPECFYTFVDLKKEFHKCCPNAGPVKDLTLLSMLDYVCIQATVEQEAGLREVKDMVLLILHVLADPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFLS... | [
"GO:0008150",
"GO:0009653",
"GO:0032502",
"GO:0048856",
"GO:1904888",
"GO:1905748"
] | [
"GO:0008150",
"GO:0009653",
"GO:0032502",
"GO:0048856",
"GO:1904888",
"GO:1905748"
] | [] | [] | AF-Q7ZVR8-F1-model_v6.pdb | 7955.ENSDARP00000015568 | null | [
"IPR050666",
"IPR036397",
"IPR035979",
"IPR000504",
"IPR012337",
"IPR012677"
] | {"IPR036397": [2, 200], "IPR012337": [4, 159], "IPR012677": [210, 736], "IPR035979": [217, 733], "IPR050666": [218, 528], "IPR000504": [225, 736]} | - IPR050666: Epithelial Splicing Regulatory (family) [218-528]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [2-200]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [217-733]
- IPR000504: RNA recognition motif domain (domain) [225-736]
- IPR012337: Ribonuclease H-like superfamily... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellul... | |
Q6UWW8 | Carboxylesterase 3 | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]- carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics | Homo sapiens (Human) | 571 | Endoplasmic reticulum lumen | MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIYPLTVDGTV... | [
"GO:0003674",
"GO:0003824",
"GO:0016787",
"GO:0016788",
"GO:0052689"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016787",
"GO:0016788",
"GO:0052689"
] | [] | AF-Q6UWW8-F1-model_v6.pdb | 9606.ENSP00000304782 | [
"Q6NSL7",
"Q9BVJ2",
"Q96RJ3"
] | [
"IPR002018",
"IPR029058",
"IPR050309",
"IPR019826"
] | {"IPR029058": [30, 563], "IPR050309": [26, 554], "IPR002018": [33, 547], "IPR019826": [216, 231]} | - S-formylglutathione hydrolase
- Hormone-sensitive lipase
- Tumor necrosis factor receptor superfamily member 13C | - IPR002018: Carboxylesterase, type B (domain) [33-547]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [30-563]
- IPR050309: Type-B Carboxylesterase/Lipase (family) [26-554]
- IPR019826: Carboxylesterase type B, active site (active_site) [216-231] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), G... |
Q9VJG4 | Electron transfer flavoprotein regulatory factor 1 homolog | Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (By similarity). May act with the ETF complex to coordinate lipid homeostasis in the fat body in response to stage-specific demands | Drosophila melanogaster (Fruit fly) | 85 | Mitochondrion | MSQLRSKVISLYKHLQYLGREYPGLNGPQKFRKQIHDAFMNHKDEQDPKKIVALLAQGRYLAKEVEALYSLKKYRSVKQRYSYND | [
"GO:0002082",
"GO:0008150",
"GO:0009892",
"GO:0019222",
"GO:0043457",
"GO:0043467",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0065007",
"GO:0090324",
"GO:1901856",
"GO:1903715",
"GO:0003674",
"GO:0004857",
"GO:0030234",
"GO:0098772",
"GO:0140678"
] | [
"GO:0002082",
"GO:0008150",
"GO:0009892",
"GO:0019222",
"GO:0043457",
"GO:0043467",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0065007",
"GO:0090324",
"GO:1901856",
"GO:1903715"
] | [
"GO:0003674",
"GO:0004857",
"GO:0030234",
"GO:0098772",
"GO:0140678"
] | [] | AF-Q9VJG4-F1-model_v6.pdb | 7227.FBpp0311571 | [
null,
"Q7KN94",
"Q9W0G9"
] | [
"IPR052000",
"IPR045296",
"IPR008011"
] | {"IPR052000": [2, 83], "IPR045296": [5, 80], "IPR008011": [7, 60]} | - Electron transfer flavoprotein subunit alpha
- Acyl carrier protein, mitochondrial | - IPR052000: Electron transfer flavoprotein regulatory factor 1 (family) [2-83]
- IPR045296: ETFRF1, LYR domain (domain) [5-80]
- IPR008011: Complex 1 LYR protein domain (domain) [7-60] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites a... |
Q9WVL6 | Exostosin-like 3 | Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal- Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elo... | Mus musculus (Mouse) | 918 | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus. Cell membrane. Nucleus. Note=Interaction with REG3A induces its translocation to the nucleus | MTGYTMLRNGGVGNGGQTCMLRWSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGSELCEVKHVLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKVTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAFGSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGEMQEPTVLRPADLEKQLFSLPHWRTDGHNHVIINLSRKSDTQNLLYNVSTGRHVAQSTFYAAQYRAGFDLVVSPLVH... | [
"GO:0003674",
"GO:0016500",
"GO:0038023",
"GO:0060089",
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0016500",
"GO:0038023",
"GO:0060089"
] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q9WVL6-F1-model_v6.pdb | 10090.ENSMUSP00000153547 | [
"Q9JLK2",
"Q9R206",
"P58158",
"Q8R087",
"Q9JKV7",
"Q91ZN5",
"Q9EPL0",
"Q9EPS3",
"Q9ES89",
"Q9EPL1"
] | [
"IPR029044",
"IPR040911",
"IPR015338",
"IPR004263"
] | {"IPR029044": [658, 911], "IPR004263": [143, 917], "IPR040911": [192, 499], "IPR015338": [662, 903]} | - Exostosin-like 1
- Exostosin-like 2
- Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
- Heparan sulfate 2-O-sulfotransferase 1
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
- Xylosyltransferase 2
- Adenosine 3'-phospho 5'-phosphosulfate transporter 1
- Beta-1,4-galactosyltransf... | - IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [658-911]
- IPR040911: Exostosin, GT47 domain (domain) [192-499]
- IPR015338: Glycosyl transferase 64 domain (domain) [662-903]
- IPR004263: Exostosin-like (family) [143-917] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0008375 (acetylglucosaminyltransferase activity)
Biological... |
Q08BS4 | Histone-lysine N-methyltransferase EZH2 | Polycomb group (PcG) protein. Catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. May regulate the circadian clock via histone methylation at the promoter of the circadian genes | Danio rerio (Zebrafish) (Brachydanio rerio) | 760 | Nucleus | MGLTGRKSEKGPVCWRRRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTDILNQEWKLRRIQPVHIMTPVSSLRGTRECTVDSGFSEFSRQVIPLKTLNAVASVPVMYSWSPLQQNFMVEDETVLHNIPYMGDEILDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALNQYSDNEEDDEEDDHHDYKFEKMDLCDGKDDAEDHKEQLSSESHNNDGSKKFPSDKIFEAISSMFPDKGSTEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFQATPNTYK... | [
"GO:0003674",
"GO:0003712",
"GO:0003713",
"GO:0003824",
"GO:0008168",
"GO:0008170",
"GO:0008276",
"GO:0008757",
"GO:0016278",
"GO:0016279",
"GO:0016740",
"GO:0016741",
"GO:0030674",
"GO:0042054",
"GO:0046976",
"GO:0060090",
"GO:0140096",
"GO:0140110",
"GO:0140938",
"GO:0140993"... | [] | [
"GO:0003674",
"GO:0003712",
"GO:0003713",
"GO:0003824",
"GO:0008168",
"GO:0008170",
"GO:0008276",
"GO:0008757",
"GO:0016278",
"GO:0016279",
"GO:0016740",
"GO:0016741",
"GO:0030674",
"GO:0042054",
"GO:0046976",
"GO:0060090",
"GO:0140096",
"GO:0140110",
"GO:0140938",
"GO:0140993"... | [] | AF-Q08BS4-F1-model_v6.pdb | 7955.ENSDARP00000023693 | [
"E7F8W3",
"F1Q982",
"Q4QRF4",
"Q7T3E6",
"Q1LVC2",
"A3KNA6",
"Q5PQY5",
"B7ZUU4",
"Q7ZW28",
"E7F8F2",
"Q9PTH4",
"A0A2R8QQ41",
"Q7T1S3",
"Q7T2T7",
"B0R1D5",
"Q90440",
"F6PBE4",
"E7F6H4",
"F1RDZ9",
"A8KC45",
"Q7ZTX2",
"F1R653",
"Q561S9",
"F1QQ03",
"F1Q5H5",
"B3DK16",
... | [
"IPR021654",
"IPR026489",
"IPR044439",
"IPR046341",
"IPR045318",
"IPR041355",
"IPR001214",
"IPR041343",
"IPR033467",
"IPR001005",
"IPR048358"
] | {"IPR046341": [519, 750], "IPR045318": [10, 755], "IPR021654": [39, 68], "IPR041343": [159, 262], "IPR001005": [160, 490], "IPR048358": [270, 322], "IPR026489": [517, 619], "IPR033467": [569, 607], "IPR041355": [573, 604], "IPR044439": [623, 742], "IPR001214": [626, 747]} | - Polycomb protein suz12-B
- Polycomb protein suz12-A
- Polycomb protein eed
- Histone-binding protein RBBP4
- Zinc finger protein AEBP2
- E3 ubiquitin-protein ligase RING2
- Histone-binding protein RBBP7
- DNA (cytosine-5)-methyltransferase
- Polycomb complex protein BMI-1-A
- Histone H3.3 | - IPR021654: Histone-lysine N-methyltransferase EZH1/EZH2 (family) [39-68]
- IPR026489: CXC domain (domain) [517-619]
- IPR044439: EZH2, SET domain (domain) [623-742]
- IPR046341: SET domain superfamily (homologous_superfamily) [519-750]
- IPR045318: Histone-lysine N-methyltransferase EZH1/2-like (family) [10-755]
- IP... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-str... |
Q70Z53 | Protein FRA10AC1 | May be involved in pre-mRNA splicing | Homo sapiens (Human) | 315 | Nucleus | MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQDLFL | [
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016070",
"GO:0016071",
"GO:0032774",
"GO:0034654",
"GO:0043170",
"GO:0044238",
"GO:0090304"... | [
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016070",
"GO:0016071",
"GO:0032774",
"GO:0034654",
"GO:0043170",
"GO:0044238",
"GO:0090304"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q70Z53-F1-model_v6.pdb | 9606.ENSP00000360488 | [
"Q92951",
"Q9BWD2",
"Q99492",
"Q9BTZ4",
"Q5VY29",
"Q96EM3",
"Q6IPD8",
"Q96LF5"
] | [
"IPR050645",
"IPR019129"
] | {"IPR050645": [52, 265], "IPR019129": [104, 219]} | - Zinc finger protein 32
- Spliceosome-associated protein CWC27 homolog
- Splicing factor ESS-2 homolog
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
- Calcium homeostasis endoplasmic reticulum protein
- Leucine-rich glioma-inactivated protein 1
- Splicing factor 3B subunit 2
- Protein Red | - IPR050645: Histidine Acid Phosphatase (family) [52-265]
- IPR019129: Folate-sensitive fragile site protein Fra10Ac1 (family) [104-219] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
P70266 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | Synthesis and degradation of fructose 2,6-bisphosphate | Mus musculus (Mouse) | 471 | null | MSREMGELTQTRLQKIWIPHSSSSSLLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYRNYEFFRPDNMEAQLIRKQCALAALKDVHKYLSREEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDIIAENIKQVKLGSPDYIDCDQEKVLEDFLKRIECYEINYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHVQSRTAYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQSISSLKVWTSHMKRTIQTAEALGVPY... | [
"GO:0006109",
"GO:0006110",
"GO:0006140",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0010563",
"GO:0019219",
"GO:0019222",
"GO:0030811",
"GO:0030812",
"GO:0033121",
"GO:0033122",
"GO:0043467",
"GO:0043470",
"GO:0045820",
"GO:0045912",
"GO:0045934",
"GO:0045936"... | [
"GO:0006109",
"GO:0006110",
"GO:0006140",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0010563",
"GO:0019219",
"GO:0019222",
"GO:0030811",
"GO:0030812",
"GO:0033121",
"GO:0033122",
"GO:0043467",
"GO:0043470",
"GO:0045820",
"GO:0045912",
"GO:0045934",
"GO:0045936"... | [
"GO:0003674",
"GO:0003824",
"GO:0004331",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0019203",
"GO:0042578",
"GO:0050308"
] | [] | AF-P70266-F1-model_v6.pdb | 10090.ENSMUSP00000079692 | [
"Q64479",
"Q3UTH5",
"Q9JID0",
"Q8BRK8",
"A7UAK5",
"Q91WG5",
"Q8VDX7",
"O08528",
"Q9QXD6",
"Q8CJ41",
"Q5EG47",
"Q91W97",
"Q8BZA9",
"P52792",
"Q8VEI9",
"Q9WUA3",
"Q9QXD7",
"Q3UEA4",
"Q6PAM0",
"Q9R078",
"Q924M7",
"Q5PRE8",
"Q9JK94"
] | [
"IPR013078",
"IPR027417",
"IPR029033",
"IPR001345",
"IPR013079",
"IPR003094"
] | {"IPR027417": [41, 252], "IPR029033": [250, 470], "IPR003094": [32, 453], "IPR013078": [253, 439], "IPR013079": [31, 251], "IPR001345": [256, 265]} | - Fructose-1,6-bisphosphatase isozyme 2
- Fructose-1,6-bisphosphatase 1
- Fructose-2,6-bisphosphatase TIGAR
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, muscle type
- ATP-dependent 6-phosphofructokinase, platelet type
- cAMP-dependent protein kinase catalytic subunit beta
- c... | - IPR013078: Histidine phosphatase superfamily, clade-1 (family) [253-439]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [41-252]
- IPR029033: Histidine phosphatase superfamily (homologous_superfamily) [250-470]
- IPR001345: Phosphoglycerate/bisphosphoglycerate mutase, active... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0019203 (carbohydrate phosphatase activity), GO:0050... |
P0DO58 | Anthocyanidin 3-O-galactosyltransferase 3GT1 | Flavonoid 3-O-glycosyltransferase involved in the biosynthesis of anthocyanins conferring flower red/pink colors, mainly anthocyanidin 3-O-glycosides. Catalyzes the addition of UDP-sugar to the 3-OH of anthocyanidin, with a preference for UDP- galactose (UDP-Gal) as sugar donor and cyanidin as substrate; able to use de... | Rhododendron delavayi (Rhododendron) (Rhododendron arboreum subsp | 464 | null | MTKNISRDRHVAVLPFPFSSHAGRLLTLVRRLAAAAPNVTFSFYSTPKSIESLFSPAERVPGNVRPYAVPDGVPEGHVFSGEPVEHVNLYLTAVGEGESLRGVLKAAEAETGRRIGCVMSDAFMWFAGDLAEEMGVPWVPFMAGGANSITAHFYTDLIRETVGMHDIVGRENDIVKFIPGFSELRLGDLPTGVLFGNLESPFAIMLHKMGRALPKATAIAINSFEELDPDIIQDLKSKFKMILNVSPFSAISLPSSPPPPPTSYTDEYGCMPWLDNRKAASVAYIGFGTLATPPPVEIAALAEALEASGTPFLWSLKDNP... | [
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009812",
"GO:0009813",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009962",
"GO:0009963",
"GO:0009987",
"GO:0016137",
"GO:0016138",
"GO:0019222",
"GO:0031537",
"GO:0031539",
"GO:0031540",
"GO:0031542",
"GO:0033485",
"GO:0048518"... | [
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009812",
"GO:0009813",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009962",
"GO:0009963",
"GO:0009987",
"GO:0016137",
"GO:0016138",
"GO:0019222",
"GO:0031537",
"GO:0031539",
"GO:0031540",
"GO:0031542",
"GO:0033485",
"GO:0048518"... | [
"GO:0003674",
"GO:0003824",
"GO:0008194",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0035251",
"GO:0046527",
"GO:0047213"
] | [] | AF-P0DO58-F1-model_v6.pdb | null | null | [
"IPR002213",
"IPR035595"
] | {"IPR002213": [10, 435], "IPR035595": [341, 384]} | - IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [10-435]
- IPR035595: UDP-glycosyltransferase family, conserved site (conserved_site) [341-384] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0046527 (glucosyltransferase activity), GO:0035251 (UDP-glu... | |
P0DO59 | Anthocyanidin 3-O-galactosyltransferase 3GT6 | Flavonoid 3-O-glycosyltransferase involved in the biosynthesis of anthocyanins conferring flower red/pink colors, mainly anthocyanidin 3-O-glycosides. Catalyzes the addition of UDP-sugar to the 3-OH of anthocyanidin, with a preference for UDP- galactose (UDP-Gal) as sugar donor and cyanidin as substrate; able to use de... | Rhododendron delavayi (Rhododendron) (Rhododendron arboreum subsp | 454 | null | MTNSSKGRHVAVLPFPFSTHAAPILSIIRRLASAAPDVTFSFFSTPQSIQTLFPSENPENNIRPHAISDGVPEGFVFSGKHHEDINLFLAAGKESFEAGMKAAEAETGRRIDCVVSDAFMWFSCELAEEMGVPWVTLWVSGACSLAAHCYTDLIRETVGMHDTAGREDEIVKFVPGFSEVRLGDLPSGVVYGNLESPFSMMLYKMGQVLHKAAAVAINSFDELEPEPVKVLASKLKLLTCGPFNPISPPPSSNLDEYGCIPWLDRRKAASVAYIGFGTVATPPPVELAALAEALEASSTPFLWSLRDNPKQHLPEGFLKR... | [
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009812",
"GO:0009813",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009962",
"GO:0009963",
"GO:0009987",
"GO:0016137",
"GO:0016138",
"GO:0019222",
"GO:0031537",
"GO:0031539",
"GO:0031540",
"GO:0031542",
"GO:0033485",
"GO:0048518"... | [
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009812",
"GO:0009813",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009962",
"GO:0009963",
"GO:0009987",
"GO:0016137",
"GO:0016138",
"GO:0019222",
"GO:0031537",
"GO:0031539",
"GO:0031540",
"GO:0031542",
"GO:0033485",
"GO:0048518"... | [
"GO:0003674",
"GO:0003824",
"GO:0008194",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0035251",
"GO:0046527",
"GO:0047213"
] | [] | AF-P0DO59-F1-model_v6.pdb | null | null | [
"IPR002213"
] | {"IPR002213": [9, 415]} | - IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [9-415] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0046527 (glucosyltransferase activity), GO:0035251 (UDP-glu... | |
Q568K9 | Protein FAM50A | Probably involved in the regulation of pre-mRNA splicing | Danio rerio (Zebrafish) (Brachydanio rerio) | 341 | Nucleus | MAQYKGAASEAGRAMQLMKKREREREQLEQLKQKIAEDNMVKSNIDKKFSAHYDAVEQELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQLKLEKQKEKKRKEEQKRKIASLSFNPDEGEDEEEEEEEEEEEEEDEIEEEICLPVKKKKLGKNPDVDTSFLPDRDREEEENRLREELRQEWERKQEKIKSEEIEITFSYWDGSGHRKTVKMKKGNTIQQFLQRALEVLRKDFSELRSAGVEHLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDIRLVNDATVEKDESHAGKVVLRSWYEKNKHI... | [
"GO:0001501",
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0008150",
"GO:0009653",
"GO:0009790",
"GO:0009792",
"GO:0009887",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0032501",
"GO:0032502",
"GO:0043009",
"GO:0043484",
"GO:0048024",
"GO:0048513"... | [
"GO:0001501",
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0008150",
"GO:0009653",
"GO:0009790",
"GO:0009792",
"GO:0009887",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0032501",
"GO:0032502",
"GO:0043009",
"GO:0043484",
"GO:0048024",
"GO:0048513"... | [] | [] | AF-Q568K9-F1-model_v6.pdb | 7955.ENSDARP00000028381 | [
"Q7T293",
"F1QNX7",
"F8W2E1",
"Q6DRM1",
"F1QFU5",
"Q66I61",
"Q8JHH2",
"Q6DGP2",
"Q568A0",
"Q3KR14",
"Q5U3F2",
"A5WUR0",
"Q6GQN4",
"F1Q5L6",
"Q66HZ8",
"F1RCD0",
"Q5XJ46",
"F1Q8W0",
"Q08C72",
"Q6IQL3",
"F1QF68",
"A0A0R4IU36"
] | [
"IPR048337",
"IPR007005"
] | {"IPR007005": [1, 341], "IPR048337": [199, 339]} | - FLJ22626-like
- Zgc:103692
- Regulator of nonsense transcripts 3B
- Pre-mRNA-splicing factor SLU7
- Pre-mRNA-splicing factor syf2
- Splicing regulator SDE2
- PRKR-interacting protein 1 homolog
- Protein FAM32A-like
- Pre-mRNA-splicing factor CWC22 homolog
- Peptidyl-prolyl cis-trans isomerase | - IPR048337: FAM50A/XAP5, C-terminal domain (domain) [199-339]
- IPR007005: XAP5 protein (family) [1-341] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organism... |
P0A8V6 | Fatty acid metabolism regulator protein | Multifunctional regulator of fatty acid metabolism. Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE. Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the g... | Escherichia coli (strain K12) | 239 | Cytoplasm | MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | AF-P0A8V6-F1-model_v6.pdb | 511145.b1187 | [
"P77697",
"Q9S683",
"Q2M8N4",
"Q47680",
"Q2M8E9",
"Q2M7R8",
"Q2MBY3",
"Q9R830",
"Q9S6P7",
"Q2M8E8",
"Q2M9C5",
"Q2M8Q8",
"Q59383",
"Q2MAQ4",
"Q47241",
"Q2MAP5",
"P56606",
"Q8X4G9",
"P36658",
"Q2MBT3",
"Q06065",
"Q2M6T6",
"Q2M654",
"Q8KMZ5",
"P69451"
] | [
"IPR028374",
"IPR036388",
"IPR036390",
"IPR000524",
"IPR014178",
"IPR008920"
] | {"IPR036388": [1, 79], "IPR036390": [11, 88], "IPR008920": [79, 239], "IPR014178": [1, 239], "IPR000524": [6, 74], "IPR028374": [72, 234]} | - HTH-type transcriptional repressor FabR
- 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
- 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
- 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
- Acyl-coenzyme A dehydrogenase
- Long-chain-fatty-acid--CoA ligase
- 3-oxoacyl-[acyl-carrier-protein] synthase 1... | - IPR028374: FadR, C-terminal domain (domain) [72-234]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [1-79]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [11-88]
- IPR000524: Transcription regulator HTH, GntR (domain) [6-74]
- IPR014178: Fatty... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulatio... |
P0C2W1 | F-box/SPRY domain-containing protein 1 | Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Regulates neuron migration during bra... | Homo sapiens (Human) | 286 | Secreted. Postsynaptic cell membrane. Presynaptic cell membrane. Nucleus. Note=Secreted by a non-classical mechanism | MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0071944",
"GO:0110165"
] | AF-P0C2W1-F1-model_v6.pdb | 9606.ENSP00000310332 | [
"Q9Y6E4",
"Q8TAY2",
"Q92880",
"Q9UPW8",
"Q5VYM8",
"Q86SV1",
"Q7Z5U6",
"Q9NUX6",
"Q8IYW1",
"Q96SK5",
"Q9ULI8"
] | [
"IPR013320",
"IPR001870",
"IPR003877",
"IPR001810",
"IPR043136",
"IPR050672",
"IPR036047",
"IPR035784"
] | {"IPR036047": [38, 87], "IPR013320": [79, 283], "IPR043136": [110, 284], "IPR050672": [44, 278], "IPR001810": [33, 84], "IPR001870": [92, 284], "IPR035784": [112, 286], "IPR003877": [152, 284]} | - E3 ubiquitin-protein ligase MYCBP2
- S-phase kinase-associated protein 1
- S-phase kinase-associated protein 1
- Cullin-1
- Protein unc-13 homolog A
- SPRY domain-containing protein 3
- E3 ubiquitin-protein ligase SIAH1
- F-box/WD repeat-containing protein 7
- WD repeat-containing protein 53
- MAGUK p55 subfamily mem... | - IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [79-283]
- IPR001870: B30.2/SPRY domain (domain) [92-284]
- IPR003877: SPRY domain (domain) [152-284]
- IPR001810: F-box domain (domain) [33-84]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [110-284]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological p... |
P78594 | Cytosine deaminase | Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 150 | Cytoplasm. Nucleus | MTFDDKKGLQVALDQAKKSYSEGGIPIGSCIISSDDTVLGQGHNERIQKHSAILHGEMSALENAGRLPGKTYKDCTIYTTLSPCSMCTGAILLYGFKRVVMGENVNFLGNEKLLIENGVEVVNLNDQECIDLMAKFIKEKPQDWNEDIGE | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-P78594-F1-model_v6.pdb | null | null | [
"IPR002125",
"IPR016193",
"IPR016192"
] | {"IPR016193": [5, 148], "IPR002125": [3, 121], "IPR016192": [55, 91]} | - IPR002125: Cytidine and deoxycytidylate deaminase domain (domain) [3-121]
- IPR016193: Cytidine deaminase-like (homologous_superfamily) [5-148]
- IPR016192: APOBEC/CMP deaminase, zinc-binding (binding_site) [55-91] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines), GO:00192... | |
P12319 | High affinity immunoglobulin epsilon receptor subunit alpha | High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoact... | Homo sapiens (Human) | 257 | Cell membrane; Single-pass type I membrane protein | MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTRKGFRLLNPHPKPNPKNN | [
"GO:0001775",
"GO:0002250",
"GO:0002252",
"GO:0002263",
"GO:0002274",
"GO:0002275",
"GO:0002278",
"GO:0002279",
"GO:0002366",
"GO:0002376",
"GO:0002437",
"GO:0002438",
"GO:0002443",
"GO:0002444",
"GO:0002447",
"GO:0002448",
"GO:0002449",
"GO:0002460",
"GO:0002524",
"GO:0002526"... | [
"GO:0001775",
"GO:0002250",
"GO:0002252",
"GO:0002263",
"GO:0002274",
"GO:0002275",
"GO:0002278",
"GO:0002279",
"GO:0002366",
"GO:0002376",
"GO:0002437",
"GO:0002438",
"GO:0002443",
"GO:0002444",
"GO:0002447",
"GO:0002448",
"GO:0002449",
"GO:0002460",
"GO:0002524",
"GO:0002526"... | [] | [] | AF-P12319-F1-model_v6.pdb | 9606.ENSP00000357097 | [
"Q5VTW4",
"P0DP08",
"Q9UEK0",
"Q32MC4",
"P43405",
"Q96E94",
"P07948",
"Q9UM99",
"Q13963",
"Q8N5D7",
"Q8WXX8",
"Q54A81",
"Q9NYK0",
"Q8IUN9"
] | [
"IPR036179",
"IPR050488",
"IPR007110",
"IPR003598",
"IPR013783",
"IPR003599"
] | {"IPR013783": [26, 201], "IPR036179": [26, 198], "IPR050488": [27, 199], "IPR007110": [30, 193], "IPR003599": [36, 195], "IPR003598": [42, 183]} | - High affinity immunoglobulin epsilon receptor subunit gamma
- High affinity immunoglobulin epsilon receptor subunit beta
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase Fyn
- Mast cell carboxypeptidase A
- Immunoglobulin heavy variable 4-38-2
- Tyrosine-protein kinase Lyn
- B-lymphocyte antigen CD20
- Immunog... | - IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [26-198]
- IPR050488: Immunoglobulin Fc region receptor (family) [27-199]
- IPR007110: Immunoglobulin-like domain (domain) [30-193]
- IPR003598: Immunoglobulin subtype 2 (domain) [42-183]
- IPR013783: Immunoglobulin-like fold (homologous_super... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0140352 (exp... |
Q9Y324 | rRNA-processing protein FCF1 homolog | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | Homo sapiens (Human) | 198 | Nucleus, nucleolus | MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [] | [] | AF-Q9Y324-F1-model_v6.pdb | 9606.ENSP00000344393 | [
"Q9Y400",
"Q9Y3B2",
"Q5STR3",
"Q96AT5",
"R4GMW7",
"Q9P211",
"Q9Y3U7",
"Q96G21",
"Q76M58",
"Q13901",
"P62249",
"Q9NVF2",
"Q96IP8",
"Q9Y3Z9",
"P69849",
"Q96E72",
"Q6IPF8",
"Q9Y5J1",
"Q9UI98",
"Q8NHS8",
"Q68CQ4",
"Q9UNX4",
"Q9UNX5",
"P39019",
"Q92555",
"Q8TBR6",
"Q9B... | [
"IPR037503",
"IPR029060",
"IPR006984",
"IPR002716"
] | {"IPR029060": [65, 189], "IPR006984": [92, 188], "IPR037503": [57, 187], "IPR002716": [67, 166]} | - WD repeat-containing protein 46
- KRR1 small subunit processome component homolog
- Ribosomal RNA small subunit methyltransferase NEP1
- Probable U3 small nucleolar RNA-associated protein 11
- Deoxynucleotidyltransferase terminal-interacting protein 2
- Something about silencing protein 10
- Nucleolar protein 58
- U3... | - IPR037503: rRNA-processing protein Fcf1, PIN domain (domain) [57-187]
- IPR029060: PIN-like domain superfamily (homologous_superfamily) [65-189]
- IPR006984: Fcf1/UTP23 (family) [92-188]
- IPR002716: PIN domain (domain) [67-166] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO... |
Q5AJV5 | Filamentous growth regulator 23 | Putative adhesin which may be involved in cell adhesion and virulence (By similarity). Involved in the regulation of filamentous growth | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,114 | Cell membrane; Lipid-anchor, GPI- anchor | MFASYLLLVLWIIRLVPTTHAHTGNDAEYLLNTVLKRDATSLSRNAYLDSEATSGATNYCSDCDNDEVIVTVDGTSTIWTILLDSTISTLVTTTSTEKTTLTSCGQSCTKSKDASSVSSSSASSSTSRSLIFRTSTKTVTDTTTLPTVTEINTFTTTDSHIVLVYTDINSESTITGDYTFIKNKNTRTVIITDYVTSTVGGETQIVTQTTTSVVYELVVTCPDHDFATTLTGSETFVPPTTAPKPVETPSPEPSTTILSIKSESSVPSATTSVLDTSITLETSSSSIEFSTSTQESSSIGPSSSSSIGSCTSSSISTEES... | [
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170",
"GO:0036180",
"GO:0040007",
"GO:0042594",
"GO:0044182",
"GO:0050896",
"GO:0051716"
] | [
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170",
"GO:0036180",
"GO:0040007",
"GO:0042594",
"GO:0044182",
"GO:0050896",
"GO:0051716"
] | [] | [] | AF-Q5AJV5-F1-model_v6.pdb | 237561.Q5AJV5 | [
"Q59UY8",
"Q59WE2"
] | null | NaN | - DNA repair protein RAD51 homolog
- E3 ubiquitin ligase complex SCF subunit | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0030447 (filamentous growth), GO:0071840 (cellular co... | |
P06971 | Ferrichrome outer membrane transporter/phage receptor | Involved in the uptake of iron in complex with ferrichrome, a hydroxamate-type siderophore. Binds and transports ferrichrome-iron across the outer membrane. In addition to its role in ferrichrome-iron transport, transports the antibiotic albomycin, which is a structural analog of ferrichrome, and acts as a receptor for... | Escherichia coli (strain K12) | 747 | Cell outer membrane; Multi-pass membrane protein | MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFD... | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0008150",
"GO:0015891",
"GO:0030001",
"GO:0044718",
"GO:0051179",
"GO:0051234",
"GO:1901678"
] | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0008150",
"GO:0015891",
"GO:0030001",
"GO:0044718",
"GO:0051179",
"GO:0051234",
"GO:1901678"
] | [] | [] | AF-P06971-F1-model_v6.pdb | 511145.b0150 | [
"P06996",
"P77094",
"Q2M6R8",
"P02931",
"Q2MBK9",
"Q2M5W5",
"Q2M622",
"Q2M9J3",
"P0A910",
"P77548",
"P77292",
"P77372",
"Q2M9G5",
"P77711",
"Q2MBF5",
"Q2MAS4",
"Q2MBB1",
"Q2M9J2",
"Q2M5U9",
"P97239",
"P77093",
"Q2M623"
] | [
"IPR010105",
"IPR010917",
"IPR037066",
"IPR000531",
"IPR010916",
"IPR012910",
"IPR039426",
"IPR036942"
] | {"IPR037066": [54, 193], "IPR036942": [194, 747], "IPR039426": [33, 747], "IPR010105": [78, 747], "IPR012910": [76, 180], "IPR000531": [254, 716], "IPR010916": [1, 47], "IPR010917": [730, 747]} | - Protein TonB
- Biopolymer transport protein ExbD
- Biopolymer transport protein ExbB
- Iron(3+)-hydroxamate import ATP-binding protein FhuC
- Iron(3+)-hydroxamate-binding protein FhuD
- Iron(3+)-hydroxamate import system permease protein FhuB
- Ferric siderophore reductase
- Ferric enterobactin-binding periplasmic pr... | - IPR010105: TonB-dependent siderophore receptor (family) [78-747]
- IPR010917: TonB-dependent receptor, conserved site (conserved_site) [730-747]
- IPR037066: TonB-dependent receptor, plug domain superfamily (homologous_superfamily) [54-193]
- IPR000531: TonB-dependent receptor-like, beta-barrel (domain) [254-716]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0015643 (toxic substance binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0019904 (protein domain specific binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion bindin... |
Q9NSG2 | FIGNL1-interacting regulator of recombination and mitosis | Regulates PLK1 kinase activity at kinetochores and promotes faithful chromosome segregation in prometaphase by bridging kinase and phosphatase activities. Phosphorylation of FIRRM by PLK1 negatively regulates its interaction with the phosphatase, PPP1CC, thus creating a negative feedback loop for maintaining proper PLK... | Homo sapiens (Human) | 853 | Chromosome, centromere, kinetochore. Nucleus. Chromosome, centromere. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Exhibits cell-cycle-dependent distribution during mitosis. Detected in the nucleus in interphase. Colocalizes with PLK1 to the centromeres in a nearby prometaphase cells. Relocates to the central spindl... | MFLPHMNHLTLEQTFFSQVLPKTVKLFDDMMYELTSQARGLSSQNLEIQTTLRNILQTMVQLLGALTGCVQHICATQESIILENIQSLPSSVLHIIKSTFVHCKNSESVYSGCLHLVSDLLQALFKEAYSLQKQLMELLDMVCMDPLVDDNDDILNMVIVIHSLLDICSVISSMDHAFHANTWKFIIKQSLKHQSIIKSQLKHKDIITSLCEDILFSFHSCLQLAEQMTQSDAQDNADYRLFQKTLKLCRFFANSLLHYAKEFLPFLSDSCCTLHQLYLQIHSKFPPSLYATRISKAHQEEIAGAFLVTLDPLISQLLTF... | [
"GO:0000278",
"GO:0001932",
"GO:0006139",
"GO:0006259",
"GO:0006281",
"GO:0006950",
"GO:0006974",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019222",
"GO:0022402",
"GO:0031399",
"GO:0033554",
"GO:0036297",
"GO:0042325",
"GO:0043170",
"GO:0043549"... | [
"GO:0000278",
"GO:0001932",
"GO:0006139",
"GO:0006259",
"GO:0006281",
"GO:0006950",
"GO:0006974",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019222",
"GO:0022402",
"GO:0031399",
"GO:0033554",
"GO:0036297",
"GO:0042325",
"GO:0043170",
"GO:0043549"... | [] | [
"GO:0000775",
"GO:0000776",
"GO:0000779",
"GO:0000793",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005694",
"GO:0005730",
"GO:0005737",
"GO:0005819",
"GO:0005829",
"GO:0005856",
"GO:0015630",
"GO:0030496",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227"... | AF-Q9NSG2-F1-model_v6.pdb | 9606.ENSP00000286031 | [
"Q9NWS1"
] | [
"IPR027902"
] | {"IPR027902": [1, 848]} | - PCNA-interacting partner | - IPR027902: Protein of unknown function DUF4487 (family) [1-848] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (ni... |
Q5A7S7 | Fork-head transcriptional regulator 2 | Transcription factor required for the morphogenesis of true hyphal as well as yeast cells. Contributes to virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 687 | Nucleus | MSAQFITPKKRPHSPLDSNELLPSFEDPQDMINAVVSTLSAPEEKTNVSIAYANEKNQATEIQAYAKIAGKDWTFYVKSLAVSIGRNIELSAPSNTNITTPLIDIDLGPAKVVSRSHAAITYNLDLRCWELKVLGRNGARIDGQKVNVDSPNVNALHSGAILDIGGTQMMFILPDAPAVVAPKMLEKCLLRYKEQQQQQNKRISSGPGIGGSTSFQMFDKAHLTHSPSSISANSLQSNLDQDLSKEEAKDIKPPYSYATMITQAILSNPQGVMSLSEIYNWIADHYAYYKYSKTGWQNSIRHNLSLNKAFEKVPRRPNEP... | [
"GO:0000902",
"GO:0001558",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0006974",
"GO:0008150",
"GO:0009653",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030308",
"GO:0030447",
"GO:0032502",
"GO:0033554",
"GO:0040007"... | [
"GO:0000902",
"GO:0001558",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0006974",
"GO:0008150",
"GO:0009653",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030308",
"GO:0030447",
"GO:0032502",
"GO:0033554",
"GO:0040007"... | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5A7S7-F1-model_v6.pdb | 237561.Q5A7S7 | [
"Q59V96",
"Q5AFP3"
] | [
"IPR000253",
"IPR008984",
"IPR018122",
"IPR036388",
"IPR036390",
"IPR001766",
"IPR030456"
] | {"IPR008984": [68, 176], "IPR036388": [238, 343], "IPR036390": [251, 340], "IPR000253": [81, 165], "IPR001766": [250, 350], "IPR018122": [252, 265], "IPR030456": [296, 302]} | - Transcription factor of morphogenesis MCM1
- Cyclin-dependent kinase 1 | - IPR000253: Forkhead-associated (FHA) domain (domain) [81-165]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [68-176]
- IPR018122: Fork head domain conserved site1 (conserved_site) [252-265]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [238-343]
- IPR036390... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
Q59ZC8 | Fork-head transcriptional regulator FHL1 | In complex with IFH1, acts as a transcriptional regulator of rRNA and ribosomal protein genes. The FHL1-IFH1 complex is targeted to the ribosomal protein genes by the DNA-binding factor TBF1 | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,152 | Nucleus | MSHIDGDDHMTKDLIDSLESKDNDLSLVTSNTQIPDVEVANLTHDADEINQLFDTATNNVLPESNKKDKPIDTQDLHEDDPKAVPKTTSNGESTSNSNSVSPKLLPNDGKSTPKIQKELRRKSTFVPVTSNSKSLEPSEDDNNNNNNNSRISAYARLDFENFTFFVQTLQVVLGRKSNDETLQQNVDVHLSSKKAISRRHAKIFYNFGTQRFEISILGRNGAFVDNVFVEKGLTIPLTDGNKIQIGDIPFKFVLPSNEPNEENNNQDSSEKQFNPSDAINLRSNLYSKSSSPQSSPKRKPQPSKKVKKEPVSASNTSKDI... | [
"GO:0006139",
"GO:0006351",
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009303",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010467",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016070",
"GO:0016072"... | [
"GO:0006139",
"GO:0006351",
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009303",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010467",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016070",
"GO:0016072"... | [
"GO:0000976",
"GO:0001067",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003690",
"GO:0005488",
"GO:0043565",
"GO:1990837"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59ZC8-F1-model_v6.pdb | 237561.Q59ZC8 | [
"Q5AHX1",
"Q59Z65",
"Q5AGN3"
] | [
"IPR008984",
"IPR000253",
"IPR053364",
"IPR036388",
"IPR036390",
"IPR001766"
] | {"IPR008984": [150, 263], "IPR036388": [658, 751], "IPR036390": [658, 748], "IPR053364": [13, 1049], "IPR000253": [170, 246], "IPR001766": [657, 740]} | - Transcriptional regulator IFH1
- Transcription factor TBF1
- Proteasome subunit beta | - IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [150-263]
- IPR000253: Forkhead-associated (FHA) domain (domain) [170-246]
- IPR053364: Fork-head Transcriptional Regulator (family) [13-1049]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [658-751]
- IPR036390: W... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
Q8R507 | Ribitol-5-phosphate transferase FKTN | Catalyzes the transfer of CDP-ribitol to the distal N- acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of ... | Mus musculus (Mouse) | 461 | Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasm. Nucleus. Endoplasmic reticulum. Note=In retinal tissue, does not localize with the Golgi apparatus | MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSARNGPGSSKSKGNRVGFDSTQWRAVKKFIMLTSSQNVPVFLIDPWILESINKNFEQVKNASQGPASECRFFCVPRDFTAFALQYHLWKNEDGWFRIAENMGFQCLKTESKDPRLDGIDSLSGTEIPLHYVCKLTTHAIHLVVFHERSGNYLWHGHLRLKGHMDRKFVPFRKLQFGRYPGAFDRPELQQVTVDGLDMLIPKDPGRFLEEVPHSRFIECRYKEARAFLQQYIDDNTVDAMVFRKRAKELLQLAAKTLKDLGVPFWLSSGTCLGWYRQCGIIPYSKDVDL... | [
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0007420",
"GO:0007517",
"GO:0007519",
"GO:0008150",
"GO:0009888",
"GO:0009987",
"GO:0014706",
"GO:0014902",
"GO:0016043",
"GO:0021537",
"GO:0021543",
"GO:0021549",
"GO:0021695",
"GO:0021987",
"GO:0022037",
"GO:0030154",
"GO:0030198"... | [
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0007420",
"GO:0007517",
"GO:0007519",
"GO:0008150",
"GO:0009888",
"GO:0009987",
"GO:0014706",
"GO:0014902",
"GO:0016043",
"GO:0021537",
"GO:0021543",
"GO:0021549",
"GO:0021695",
"GO:0021987",
"GO:0022037",
"GO:0030154",
"GO:0030198"... | [] | [] | AF-Q8R507-F1-model_v6.pdb | 10090.ENSMUSP00000114699 | [
"B2RWU1",
"Q8BXL0",
"Q8VDX6",
"Q9D1Q4",
"Q9Z1M7",
"Q9D5G4",
"Q8R4Z0",
"Q8CIF0",
"Q8R2Y3",
"Q99LW7",
"Q8K253",
"Q8K0M5",
"Q9Z324",
"Q62165",
"Q9DCN3",
"Q8CG64",
"Q9D829",
"Q8BTZ7",
"Q8R474"
] | [
"IPR007074",
"IPR045587",
"IPR009644"
] | {"IPR009644": [4, 460], "IPR045587": [1, 278], "IPR007074": [290, 328]} | - Ribitol 5-phosphate transferase FKRP
- Protein O-mannose kinase
- D-ribitol-5-phosphate cytidylyltransferase
- Protein O-mannosyl-transferase 2
- Protein O-mannosyl-transferase 1
- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
- Ribitol-5-phosphate xylosyltransferase 1
- Dystroglycan 1
- Protein... | - IPR007074: LicD/FKTN/FKRP, nucleotidyltransferase domain (domain) [290-328]
- IPR045587: Ribitol-5-phosphate transferase FKTN, N-terminal (domain) [1-278]
- IPR009644: FKTN/MNN4/W02B3.4-1/T07A5.1 (family) [4-460] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016780 (phosphotransferase activity, for other substituted phosphate groups)
Biological Process (BP): GO:0008150... |
Q59QW5 | Transcriptional regulator of filamentous growth FLO8 | Transcription factor which mediates CO(2) sensing. Required for CO(2)-induced white-to-opaque switching, as well as for filamentous growth and virulence. Required for both normoxic and hypoxic biofilm formation. Hypoxic biofilm formation is a major cause of perseverance and antifungal resistance during infections | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 792 | Nucleus | MVPNTTKQVLNSLILDFLVKHQFQDTAKAFSKESPNLPSIPPLMDCSQGFLLEWWQVFFDLFQVRYGDGNSNNNPNNKLYHDYLRVQETQKHLFSQLPLIQQQQQQQHHFQQQQQQQGQQGQPFSQQQQRGIGVASGMQNQQHQFAPQHQGQPQGPGQTPQPPGSATNANFPINMPPNSNPQQQMFPINQQFAQMPNGQNQPSMEQQQRMAMMMKQQAMAAQRQQIPMNGLDPQQQQQMMNAVGGGPGNLNLQQQLFLQQQQQQQQQPKTTFQQQAQNQMNNLRQQAAMVAQQQQQQQQQQQQQGQLQGNLASAMGDSSS... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006629",
"GO:0006694",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008610",
"GO:0009058",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010037",
"GO:0010468",
"GO:0010556",
"GO:0010557"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006629",
"GO:0006694",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008610",
"GO:0009058",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010037",
"GO:0010468",
"GO:0010556",
"GO:0010557"... | [
"GO:0001216",
"GO:0003674",
"GO:0003700",
"GO:0140110"
] | [] | AF-Q59QW5-F1-model_v6.pdb | 237561.Q59QW5 | [
"Q59LY1",
"Q59WZ4",
"Q5A0W9",
"Q59N20",
"A0A1D8PFP2",
"Q59U34",
"Q59XB5",
"Q5A5R1",
"Q59Y46",
"Q5AMQ6",
"Q5ANJ4",
"Q5ACU9"
] | [
"IPR006594"
] | {"IPR006594": [6, 38]} | - Enhanced filamentous growth protein 1
- RFX-like DNA-binding protein RFX2
- Transcription activator TEC1
- Transcription activator MSS11
- Morphogenetic regulator of filamentous growth protein 1
- Transcription factor NDT80
- Biofilm and cell wall regulator 1
- Biofilm regulator 1
- Zinc cluster transcription factor ... | - IPR006594: LIS1 homology motif (conserved_site) [6-38] | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellul... |
B2RXV4 | Choline/ethanolamine transporter FLVCR1 | Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis. Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids (By similarity). Transpo... | Mus musculus (Mouse) | 560 | [Isoform 1]: Cell membrane; Multi-pass membrane protein | MARPDDEVGPAVAPGHPLGKGYLPVPKGAPDGEARLVPQNGPEALNGGPGLGPLIAGAQGGPQALIAAEEETQARLLPAGDGEDVPCPACPPRTALSPRRFVVLLIFSLYSLVNAFQWIQYSSISNVFEDFYEVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCGSVQRHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPALGTQNSTGLLAHTQNNTDLLAHNINTMFYGTAFISTFLFFLTIIAFKEKPPLPPSQAQAVLRDSP... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005740",
"GO:0005886",
"GO:0016020",
"GO:0031090",
"GO:0031966",
"GO:0031967",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005740",
"GO:0005886",
"GO:0016020",
"GO:0031090",
"GO:0031966",
"GO:0031967",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0071944",
"GO:0110165"
] | AF-B2RXV4-F1-model_v6.pdb | 10090.ENSMUSP00000082777 | [
"Q9D1P1",
"Q9DCK0",
"Q9JI39",
"Q91X72"
] | [
"IPR049680",
"IPR036259",
"IPR011701",
"IPR020846"
] | {"IPR036259": [87, 524], "IPR049680": [93, 529], "IPR011701": [109, 482], "IPR020846": [103, 522]} | - Hemopexin
- Heme transporter HRG1
- ATP-binding cassette sub-family B member 10, mitochondrial
- Proton-coupled folate transporter | - IPR049680: Choline/ethanolamine transporter FLVCR1-2/SLC49-like (family) [93-529]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [87-524]
- IPR011701: Major facilitator superfamily (family) [109-482]
- IPR020846: Major facilitator superfamily domain (domain) [103-522] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0032502 (developmental process), ... |
Q9UPI3 | Choline/ethanolamine transporter FLVCR2 | Choline uniporter that specifically mediates choline uptake at the blood-brain-barrier. Responsible for the majority of choline uptake across the blood-brain- barrier from the circulation into the brain (By similarity). Choline, a nutrient critical for brain development, is a precursor of phosphatidylcholine, as well a... | Homo sapiens (Human) | 526 | Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Present on both luminal (blood-facing) and abluminal (brain-facing) sides of brain endothelial cell plasma membranes, with higher luminal membrane expression... | MVNEGPNQEESDDTPVPESALQADPSVSVHPSVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHPSSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYMLTYIPLLLPVAWLLEKFGLRTIALTGSALNCLGAWVKLGSLKPHLFPVTVVGQLICSVAQVFILGMPSRIASVWFGANEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIEDRDELAYHISIMFYIIGGVATLLLILVIIVFKEKPKYPPSRAQSLSYALTSPDASYLGSIARLFKNLNFVLLVITYGLN... | [
"GO:0006810",
"GO:0008150",
"GO:0015695",
"GO:0015871",
"GO:0051179",
"GO:0051234",
"GO:0071705",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005740",
"GO:0005783",
"GO:0005789",
"GO:0005886",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031966",
"GO:0031967"... | [
"GO:0006810",
"GO:0008150",
"GO:0015695",
"GO:0015871",
"GO:0051179",
"GO:0051234",
"GO:0071705"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005740",
"GO:0005783",
"GO:0005789",
"GO:0005886",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031966",
"GO:0031967",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0071944"... | AF-Q9UPI3-F1-model_v6.pdb | 9606.ENSP00000238667 | null | [
"IPR049680",
"IPR036259",
"IPR011701",
"IPR020846"
] | {"IPR036259": [72, 503], "IPR049680": [67, 506], "IPR011701": [95, 453], "IPR020846": [87, 492]} | - IPR049680: Choline/ethanolamine transporter FLVCR1-2/SLC49-like (family) [67-506]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [72-503]
- IPR011701: Major facilitator superfamily (family) [95-453]
- IPR020846: Major facilitator superfamily domain (domain) [87-492] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0015232 (heme transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (met... | |
Q9HFE4 | Thiol-specific monooxygenase | Flavin-dependent oxidation of thiol-containing compounds. Probably required for the correct folding of disulfide-bonded proteins (By similarity) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | 447 | null | MCLPTIRKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGGVWNYTSTLSNKLPVPSTNPILTTEPIVGPAALPVYPSPLYRDLQTNTPIELMGYCDQSFKPQTLQFPHRHTIQEYQRIYAQPLLPFIKLATDVLDIEKKDGSWVVTYKGTKAGSPISKDIFDAVSICNGHYEVPYIPNIKGLDEYAKAVPGSVLHSSLFREPELFVGESVLVVGGASSANDLVRHLTPVAKHPIYQSLLGGGDIQNESLQQVPEITKFDPTTREIYLKGGKVLSNIDRVIYCTGYLYSVPFPSLAKLKSPETKLIDDGSHVHNVY... | [
"GO:0000166",
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0004499",
"GO:0005488",
"GO:0016491",
"GO:0016705",
"GO:0016709",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0050660",
"GO:0071949",
"GO:1901265",
"GO:1901363"
] | [] | [
"GO:0000166",
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0004499",
"GO:0005488",
"GO:0016491",
"GO:0016705",
"GO:0016709",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0050660",
"GO:0071949",
"GO:1901265",
"GO:1901363"
] | [] | AF-Q9HFE4-F1-model_v6.pdb | 284812.Q9HFE4 | [
"P87230",
"O74421",
"Q92338",
"O13972",
"O13850",
"Q9Y7Z9",
"O74826"
] | [
"IPR036188",
"IPR050346",
"IPR000960",
"IPR020946"
] | {"IPR036188": [4, 433], "IPR000960": [7, 369], "IPR050346": [7, 238], "IPR020946": [84, 371]} | - Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
- Ubiquinone biosynthesis protein coq9, mitochondrial
- 5-demethoxyubiquinone hydroxylase, mitochondrial
- Probable serine hydroxymethyltransferase, cytosolic
- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- Atypical kinase COQ8, mitochondri... | - IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [4-433]
- IPR050346: Flavin-containing monooxygenases-like (family) [7-238]
- IPR000960: Flavin monooxygenase FMO (family) [7-369]
- IPR020946: Flavin monooxygenase-like (family) [84-371] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016709 (oxidoreductase activity, a... |
P05523 | Formamidopyrimidine-DNA glycosylase | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG) and its derivatives such as guanidinohydantoin:C and spiroiminodihydantoin:C, however... | Escherichia coli (strain K12) | 269 | null | MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | AF-P05523-F1-model_v6.pdb | 511145.b3635 | [
"P0A8F8",
"P78213",
"P04395",
"Q2M9N2",
"Q2M8T5",
"P08337",
"P09030",
"Q47709",
"Q2MAS0",
"Q2MCG6",
"Q8RNJ5",
"Q2M6D5",
"Q2M6P6",
"P20625",
"Q2M8G1",
"Q9S6P7",
"Q8XBD5",
"P12295"
] | [
"IPR015887",
"IPR015886",
"IPR010979",
"IPR010663",
"IPR000214",
"IPR020629",
"IPR035937",
"IPR012319"
] | {"IPR035937": [2, 138], "IPR010979": [130, 222], "IPR020629": [1, 269], "IPR012319": [1, 115], "IPR015886": [129, 221], "IPR000214": [235, 269], "IPR010663": [241, 269], "IPR015887": [244, 268]} | - Endonuclease III
- Endonuclease III
- DNA polymerase I
- Adenine DNA glycosylase
- Dephospho-CoA kinase
- 8-oxo-dGTP diphosphatase
- Endonuclease 4
- Exodeoxyribonuclease III
- UvrABC system protein A
- DNA mismatch repair protein MutL | - IPR015887: DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site (binding_site) [244-268]
- IPR015886: Formamidopyrimidine-DNA glycosylase, H2TH DNA-binding (domain) [129-221]
- IPR010979: Small ribosomal subunit protein uS13-like, H2TH (homologous_superfamily) [130-222]
- IPR010663: Zinc finger, FPG/IleRS-t... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0043167 (ion binding),... |
P41822 | Ferritin heavy chain | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation | Aedes aegypti (Yellowfever mosquito) (Culex aegypti) | 209 | Secreted. Cytoplasm | MMKSVFFGVVAITVAILSIYQETAQAQEQTVGATDNYQWDSVDDQCLAALHRQINKEFDASIIYLKYAAYFAQEKINLPGFEKFFFHSAAEEREHGIKLIEYALMRGKAPVDKHFKLNYDHEVPTVTTGESALETALQKEVEVTKSIRGVIKACEDGSNDFHLADYLTGEYLDEQHKGQRELAEKIATLKKMKKSAPKLGEFLFDKNHM | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | AF-P41822-F1-model_v6.pdb | 7159.P41822 | [
"Q17D36",
"Q16T41",
"Q172H3",
"Q17NV7",
"Q17J46"
] | [
"IPR009078",
"IPR008331",
"IPR009040",
"IPR001519",
"IPR012347"
] | {"IPR012347": [16, 208], "IPR009078": [36, 207], "IPR001519": [41, 207], "IPR009040": [40, 193], "IPR008331": [48, 192]} | - Ferritin
- Ferritin
- Ferritin
- Ferritin
- AAEL000588-PA | - IPR009078: Ferritin-like superfamily (homologous_superfamily) [36-207]
- IPR008331: Ferritin/DPS domain (domain) [48-192]
- IPR009040: Ferritin-like diiron domain (domain) [40-193]
- IPR001519: Ferritin (family) [41-207]
- IPR012347: Ferritin-like (homologous_superfamily) [16-208] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0050801 (monoatomic ion homeostasis), GO:00550... |
I4DJ24 | Ferritin heavy chain | Stores iron in a soluble, non-toxic, readily available form (By similarity). Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). Ferritin is composed of a heavy (H) chain which is responsible for the oxidation and uptake of ferrous iro... | Papilio xuthus (Asian swallowtail butterfly) | 211 | Golgi apparatus. Secreted | MKAVLFAVAALLAVCIPISAKQCNVNPVNIPKGWITMQQSCRGSMRRQIQTEVGASLQYLAMGAHFSRDGINRPGFAKLFFDAASEEREHAMKLIDYLLMRGELETDVTSLIQIRAPERKSWESGVDALEHALKMETEVTKSIRSVIIACESDPKFNDYHLVDYLTGEFLEEQYKGQRDLAGKASTLKKMLDRHSSLGEFLFDKKLLGMDI | [
"GO:0003674",
"GO:0005488",
"GO:0005506",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0046872",
"GO:0046914"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005506",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0046872",
"GO:0046914"
] | [] | AF-I4DJ24-F1-model_v6.pdb | 66420.I4DJ24 | [
"A0A194Q6T8",
"A0A194Q9Y0",
"A0A194PXK0"
] | [
"IPR009078",
"IPR008331",
"IPR009040",
"IPR001519",
"IPR012347"
] | {"IPR012347": [21, 211], "IPR009078": [22, 209], "IPR001519": [37, 208], "IPR009040": [35, 191], "IPR008331": [46, 189]} | - Ferritin
- Serine protease snake
- Heme oxygenase | - IPR009078: Ferritin-like superfamily (homologous_superfamily) [22-209]
- IPR008331: Ferritin/DPS domain (domain) [46-189]
- IPR009040: Ferritin-like diiron domain (domain) [35-191]
- IPR001519: Ferritin (family) [37-208]
- IPR012347: Ferritin-like (homologous_superfamily) [21-211] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005506 (iron ion binding)
Biological Process (BP): GO:0008150 (bio... |
P78055 | Fructose-6-phosphate aldolase 1 | Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone (DHA) and D-glyceraldehyde 3-phosphate via an aldolization reaction. Can utilize several aldehydes as acceptor compounds in vitro, and hydroxyacetone (HA) or 1-hydroxy-butan-2-one as alternative donor substrate. Is also able to catalyze th... | Escherichia coli (strain K12) | 220 | Cytoplasm | MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLPQLHEAMGGQGRLFAQVMATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAEGIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQAKVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRTSI | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0042180",
"GO:0042182",
"GO:0044281",
"GO:0044282"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0042180",
"GO:0042182",
"GO:0044281",
"GO:0044282"
] | [] | [] | AF-P78055-F1-model_v6.pdb | 511145.b0825 | [
"P75793",
"P75794",
"Q2M915"
] | [
"IPR004731",
"IPR018225",
"IPR033919",
"IPR001585",
"IPR013785",
"IPR023001"
] | {"IPR013785": [1, 220], "IPR004731": [1, 214], "IPR023001": [1, 220], "IPR033919": [2, 213], "IPR001585": [3, 212], "IPR018225": [24, 99]} | - Arabinose 5-phosphate isomerase KdsD
- Probable dehydratase YbiW
- Putative pyruvate formate-lyase 3-activating enzyme | - IPR004731: Transaldolase type 3B/Fructose-6-phosphate aldolase (family) [1-214]
- IPR018225: Transaldolase, active site (active_site) [24-99]
- IPR033919: Transaldolase/Fructose-6-phosphate aldolase, archaeal/bacterial (family) [2-213]
- IPR001585: Transaldolase/Fructose-6-phosphate aldolase (family) [3-212]
- IPR013... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016832 (aldehyde-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process),... |
P32669 | Fructose-6-phosphate aldolase 2 | Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction. Can utilize hydroxyacetone as an alternative donor substrate. Is also able to catalyze the direct self-aldol addition of glycolaldehyde. Is less catalytically efficient than th... | Escherichia coli (strain K12) | 220 | Cytoplasm | MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQTLLEMHAPESMVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0042180",
"GO:0042182",
"GO:0044281",
"GO:0044282"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0042180",
"GO:0042182",
"GO:0044281",
"GO:0044282"
] | [] | [] | AF-P32669-F1-model_v6.pdb | 511145.b3946 | [
"Q2M8P3",
"Q2M8P1",
"Q79DT3",
"Q2M915",
"Q60139"
] | [
"IPR004731",
"IPR018225",
"IPR033919",
"IPR001585",
"IPR013785",
"IPR023001"
] | {"IPR013785": [1, 220], "IPR004731": [1, 215], "IPR023001": [1, 220], "IPR033919": [2, 213], "IPR001585": [3, 209], "IPR018225": [24, 99]} | - Multiphosphoryl transfer protein 2
- Glycerol dehydrogenase
- 6-phosphogluconate dehydrogenase, decarboxylating
- Arabinose 5-phosphate isomerase KdsD
- Glucose-6-phosphate 1-dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase | - IPR004731: Transaldolase type 3B/Fructose-6-phosphate aldolase (family) [1-215]
- IPR018225: Transaldolase, active site (active_site) [24-99]
- IPR033919: Transaldolase/Fructose-6-phosphate aldolase, archaeal/bacterial (family) [2-213]
- IPR001585: Transaldolase/Fructose-6-phosphate aldolase (family) [3-209]
- IPR013... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016832 (aldehyde-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process),... |
Q8NDD1 | 40S small subunit processome assembly factor 1 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | Homo sapiens (Human) | 293 | Chromosome. Nucleus, nucleolus | MRVDSSADPTMSQEQGPGSSTPPSSPTLLDALLQNLYDFGGTEGETEQKKIIKKRENKKRDVMASAALAAEPSPLPGSLIRGQRKSASSFFKELREERHCAPSGTPTGPEILAAAVPPSSLKNNREQVEVVEFHSNKKRKLTPDHNKNTKQANPSVLERDVDTQEFNLEKARLEVHRFGITGYGKGKERILEQERAIMLGAKPPKKSYVNYKVLQEQIKEKKAAKEEEKRLAQETDIFKKKKRKGQEDRKSKKKSAPSILSNGRIGQVGKFKNGTLILSPVDIKKINSSRVAK | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [] | [] | AF-Q8NDD1-F1-model_v6.pdb | 9606.ENSP00000355609 | [
"Q92979",
"Q9Y324",
"Q9Y5J1",
"Q9UNX4",
"Q9UNX5",
"Q9NVF2",
"P62249",
"Q96G21",
"Q76M58",
"Q96IP8",
"Q6IPF8",
"Q9Y400",
"Q96AT5",
"Q5STR3",
"Q9Y3U7",
"Q7Z3D1",
"Q9UG18",
"Q6IRY0",
"Q9NV31",
"O00566",
"Q9Y2X3",
"Q5T4L6",
"Q9BVI4",
"Q9H6R4",
"Q92577",
"Q9H855",
"Q9B... | [
"IPR052852",
"IPR027973"
] | {"IPR052852": [15, 293], "IPR027973": [134, 254]} | - U3 small nucleolar ribonucleoprotein protein MPP10
- DDB1- and CUL4-associated factor 13
- U3 small nucleolar RNA-associated protein 4 homolog
- RNA cytidine acetyltransferase
- Something about silencing protein 10
- U3 small nucleolar ribonucleoprotein protein IMP3
- Nucleolar protein 11
- WD repeat-containing prote... | - IPR052852: SSU Processome Component (family) [15-293]
- IPR027973: 40S small subunit processome assembly factor 1-like (family) [134-254] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO... |
P0DW64 | Fusexin 1 | Exhibits fusogenic activity. Mediates cell- cell fusion in mammalian cells (bilateral fusion) | Haloferax sp. (strain Q22) | 653 | Cell surface. Cell membrane; Multi-pass membrane protein | MKNGLKASVVALFFLLAASSASAATNSVDTVTYESNSDFFDGQVLQVGYTSNFATDKINVYLSESKIESETGAVADEPITFDVSHQNTYAKYPTQDTGLESITGWDAVKKTVSSKQELWDWTTTNCVDTNDAGTFTVDGYGTTDVDARANRWFDTWTGQYKYTIYCWQRNDYYGAVADIGSPDEVFRTEWRLQAGDKNPQTAVITNGDGGTGVTSNLGRYAKVSWEGSLSTGENPPLVDDEYALHSNDYEGGWRVISESRYSSYQSFVQNNADDLLGEWGAGLTTESHIESEMNGKAEEAASEFTESPLSDSEILDSSFQ... | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [] | [] | AF-P0DW64-F1-model_v6.pdb | null | null | [
"IPR049902"
] | {"IPR049902": [5, 628]} | - IPR049902: Fusexin 1 (family) [5-628] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process invo... | |
P0DW65 | Fusexin 1 | Exhibits fusogenic activity. Mediates cell- cell fusion in mammalian cells (bilateral fusion) | Haloplanus natans (strain DSM 17983 / JCM 14081 / CGMCC 1.8972 / RE-101) | 653 | Cell surface. Cell membrane; Multi-pass membrane protein | MKRVGNCWKASVAAFFLLMFTAFAAADTTSVDTVSYKSNSEFFDGEVLQAGYVSNFATDKINVHLGASEIESKTGATAEEDLTLSVSHQNTYARYPLQETGLKKIYGWEGMKKTFDTKDQLWNWVTSNCADFTEGGVAIGDRTSKVEAAAKSWYDYWTGSYNYQAFCLRKNGYYGDVADIGSPDEIFRTEWRLQAGDKNPQTAIITNGDGGSGVVSNLGRYAKVKWQGNLDTGQNPPLVDDELAIHGNNYEGGWRVISEQRYDNYWNYIKNDGNRLLDKWKSGDYSESYIEGLLNGKAENAQKRYSESPLANAEVLDSSF... | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [] | [] | AF-P0DW65-F1-model_v6.pdb | null | null | [
"IPR049902"
] | {"IPR049902": [8, 628]} | - IPR049902: Fusexin 1 (family) [8-628] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO... | |
L9ZES0 | Fusexin 1 | Exhibits fusogenic activity. Mediates cell- cell fusion in mammalian cells (bilateral fusion) | Natrinema altunense (strain JCM 12890 / CGMCC 1.3731 / AJ2) | 671 | Cell surface. Cell membrane; Multi-pass membrane protein | MRAVSDFLKNKWVAVPAVALLILSLGFLAQNYITGSFVSGDQIEYTSNSEFFDGEVFVINYIGDRTTDKIHAEIPASELASAADGEVTKELTIDITSQETYARYSTTSTSLSRIYAFKAINSEVFTDTSSSEVESRKQSWAEQNCYDIDGDSEIEQGDDYTQRFWVDGAIADYYNAQVYCVRENGYYGNIAELSSPDKEFEAEVEVKADGETPQSTTLSNSDLGQGRCDNIGEYVRACWTGLNPTGEGVPEPYNVYAIHSNTFSPEWRVISAERYSSYNSYVENNLYSQIEAWKEGSLSQEEVVSTANDQAAQAAQRVSS... | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [] | [] | AF-L9ZES0-F1-model_v6.pdb | null | null | [
"IPR049902"
] | {"IPR049902": [17, 643]} | - IPR049902: Fusexin 1 (family) [17-643] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites a... | |
C0HM55 | Fusexin 1 | Exhibits fusogenic activity. Mediates cell- cell fusion in mammalian cells when present in both cells (bilateral fusion) | Uncultured archaeon | 631 | Cell surface. Cell membrane; Multi-pass membrane protein | MRRAALILAFVLFIGLSSATVTSADSITYNSGTSEFFDGDVFAIEVTADQSTDEIDIYLGASELSEKTDGEVNQDLSIEFTHQDSKLKYSTSTSDELRDIVTLTTYYEDGFDTEQDAIDAIKSDCYDLNQNGNGSGRYSRYYSVTSPVYDYEIYCFQKNEKLATPAYIDNPDEIFTAKAELQAGDKTIQSATLSNGDAGDGTVTDLGDSKISWNGNLDLGASEPENSRVIALYSNDFENGWRIGNKQSYEDYKTFIGGGDAYDLLIDWQDGTYTASEVEDELVNTDANQAVEEASSSTTDLVNAKVKDSSLDTGSFVYDT... | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840",
"GO:0005575",
"GO:0009986",
"GO:0110165"
] | [
"GO:0007009",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0045026",
"GO:0061024",
"GO:0061025",
"GO:0071840"
] | [] | [
"GO:0005575",
"GO:0009986",
"GO:0110165"
] | AF-C0HM55-F1-model_v6.pdb | null | null | [
"IPR013783",
"IPR049902"
] | {"IPR013783": [350, 470], "IPR049902": [2, 604]} | - IPR013783: Immunoglobulin-like fold (homologous_superfamily) [350-470]
- IPR049902: Fusexin 1 (family) [2-604] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (or... | |
Q5BJ56 | RNA-binding protein fxr1 | mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for various processes, such as neurogenesis and muscle development (By similarity). Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs (By similarity). Promotes formation of some phase-sep... | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | 674 | Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Cytoplasm. Nucleus. Note=Specifically localizes to cytoplasmic ribonucleoprotein membraneless compartments (By similarity). Nuclear very early in embryonic development (at two hours post-fertilization), becoming cytoplasmic in later embryonic ... | MEDLAVEVRGSNGAYYKGFVKDVHEDSLTVVFENNWQPERQVPFHEVRMPPLPDIKKEITEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPGNQNKSVTKSSFFKCTVDVPEDLREPCSNENVHKEFKKAVGACRVYFHAETNQLIILSACESTVKRVTILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGITAIELDEDSGTFRIYGESAEAVKKARSYLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEG... | [
"GO:0007275",
"GO:0008150",
"GO:0009790",
"GO:0009888",
"GO:0032501",
"GO:0032502",
"GO:0048856",
"GO:0060429",
"GO:0061053"
] | [
"GO:0007275",
"GO:0008150",
"GO:0009790",
"GO:0009888",
"GO:0032501",
"GO:0032502",
"GO:0048856",
"GO:0060429",
"GO:0061053"
] | [] | [] | AF-Q5BJ56-F1-model_v6.pdb | 8364.ENSXETP00000032646 | [
"A0A5G3HQU1",
"Q6P1U3",
"Q6GLC9",
"F6XSY2",
"Q6DJB9"
] | [
"IPR047494",
"IPR047496",
"IPR004087",
"IPR040472",
"IPR047427",
"IPR040148",
"IPR008395",
"IPR032177",
"IPR022034",
"IPR041560",
"IPR047495",
"IPR004088",
"IPR036612",
"IPR032172"
] | {"IPR036612": [216, 377], "IPR040148": [1, 638], "IPR041560": [4, 115], "IPR047427": [61, 126], "IPR008395": [62, 114], "IPR040472": [123, 207], "IPR047494": [123, 199], "IPR004087": [217, 356], "IPR047495": [218, 280], "IPR004088": [221, 346], "IPR047496": [281, 358], "IPR022034": [354, 477], "IPR032172": [490, 564], ... | - Fragile X messenger ribonucleoprotein 1 homolog
- Sulfotransferase
- Protein argonaute-2
- Tudor domain-containing protein 3 | - IPR047494: RNA-binding protein FXR1, first type I K homology domain (domain) [123-199]
- IPR047496: RNA-binding protein FXR2, third type I K homology domain (domain) [281-358]
- IPR004087: K Homology domain (domain) [217-356]
- IPR040472: Synaptic functional regulator FMRP, KH0 domain (domain) [123-207]
- IPR047427: ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellul... |
Q9WVR4 | RNA-binding protein FXR2 | mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for adult hippocampal neurogenesis. Specifically binds to AU- rich elements (AREs) in the 3'-UTR of target mRNAs. Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid pha... | Mus musculus (Mouse) | 673 | Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm. Postsynapse. Note=Specifically localizes to cytoplasmic ribonucleoprotein membraneless compartments (By similarity). Localization to the post-synaptic region is dependent on FMR1 | MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGDEVEVYSRANEQEPCGWCLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNSSSLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRDLVGKVTGKTGKVIQGIVDK... | [
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0007420",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0009893",
"GO:0009894",
"GO:0009896",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010604",
"GO:0010605",
"GO:0010608",
"GO:0010629",
"GO:0019219",
"GO:0019222"... | [
"GO:0007275",
"GO:0007399",
"GO:0007417",
"GO:0007420",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0009893",
"GO:0009894",
"GO:0009896",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010604",
"GO:0010605",
"GO:0010608",
"GO:0010629",
"GO:0019219",
"GO:0019222"... | [] | [] | AF-Q9WVR4-F1-model_v6.pdb | 10090.ENSMUSP00000018909 | [
"P62960",
"Q91W18",
"Q61516",
"Q91VR6",
"Q9WUA9",
"Q8CJG1",
"Q921M3",
"Q9R181",
"Q9QXX8",
"Q91WJ1",
"P97855",
"P14873",
"Q8CJG0",
"Q7TN98",
"Q8C5P9",
"Q99LY1",
"P63073",
"Q9DC64",
"Q8CHC2",
"Q80TF1",
"Q96J62",
"Q8R419",
"Q812E0",
"Q7TT26",
"P42669",
"P35922"
] | [
"IPR004087",
"IPR040472",
"IPR040148",
"IPR047420",
"IPR008395",
"IPR047421",
"IPR022034",
"IPR047424",
"IPR041560",
"IPR004088",
"IPR047422",
"IPR036612",
"IPR032172"
] | {"IPR036612": [226, 369], "IPR040148": [14, 673], "IPR047421": [13, 67], "IPR041560": [14, 125], "IPR047420": [69, 136], "IPR008395": [72, 126], "IPR040472": [133, 217], "IPR047422": [133, 209], "IPR004087": [227, 366], "IPR047424": [228, 290], "IPR004088": [231, 362], "IPR022034": [364, 492], "IPR032172": [504, 578]} | - Cytoplasmic FMR1-interacting protein 2
- Cytoplasmic FMR1-interacting protein 1
- RNA-binding protein FXR1
- Fragile X messenger ribonucleoprotein 1
- Protein argonaute-2
- Poly(U)-binding-splicing factor PUF60
- Cytoplasmic polyadenylation element-binding protein 1
- Transcriptional activator protein Pur-alpha
- FMR... | - IPR004087: K Homology domain (domain) [227-366]
- IPR040472: Synaptic functional regulator FMRP, KH0 domain (domain) [133-217]
- IPR040148: Fragile X messenger ribonucleoprotein 1 (family) [14-673]
- IPR047420: RNA-binding protein FXR2, second Tudor-like Agenet domain (domain) [69-136]
- IPR008395: Agenet-like domain... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0061061 (muscle structure development), GO:0048513 (animal organ de... |
Q9Z186 | Glucose-6-phosphatase 2 | May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity) | Mus musculus (Mouse) | 355 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLF... | [
"GO:0003674",
"GO:0003824",
"GO:0004346",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0019203",
"GO:0042578",
"GO:0050308",
"GO:0050309"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004346",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0019203",
"GO:0042578",
"GO:0050308",
"GO:0050309"
] | [] | AF-Q9Z186-F1-model_v6.pdb | 10090.ENSMUSP00000005364 | [
"A6ZI46",
"Q9CRS8",
"Q05920",
"P05064",
"Q93092",
"Q0VB18",
"Q8QZY2",
"P01326",
"Q64479",
"Q9R1E0",
"Q99MX0",
"Q8BGG0",
"O08528",
"Q9ESA0",
"Q9CZI8",
"Q99KC9",
"Q9D0H2",
"Q9JK32",
"Q9Z2V4",
"Q811R8",
"P23780",
"Q91W97",
"Q3UFE9",
"Q9ET01",
"P52792",
"G5E895",
"Q00... | [
"IPR016275",
"IPR000326",
"IPR036938"
] | {"IPR036938": [16, 193], "IPR016275": [1, 354], "IPR000326": [53, 194]} | - Hexokinase-4
- Hexokinase-1
- Hexokinase HKDC1
- Hexokinase-3
- Hexokinase-2
- Phosphoglucomutase-1
- Glucose-6-phosphatase catalytic subunit 1
- GDH/6PGL endoplasmic bifunctional protein
- Glucose-6-phosphate isomerase
- Glucose-6-phosphatase 3 | - IPR016275: Glucose-6-phosphatase (family) [1-354]
- IPR000326: Phosphatidic acid phosphatase type 2/haloperoxidase (domain) [53-194]
- IPR036938: Phosphatidic acid phosphatase type 2/haloperoxidase superfamily (homologous_superfamily) [16-193] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransfer... |
Q8BSM5 | GRB2-associated-binding protein 3 | null | Mus musculus (Mouse) | 595 | null | MSTGDTVCMGWLIKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSNKPIRVIDLSECTVWKHAGPGFIRKEFQKNFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNFSHLEDGADSMESLSHMPSSFQPSPASSLHTVHVANSALLKDDRNTNSVVTEETRRESEFLFLPDYLILSNCETGRLHHASLPTRCDSWSNSNHSLAQTSFDDVFLDGLQPFISNNLVHPLHHGKVSQDFPSIRPQASLIWNREINGPSRNLMSSSPLLESSLNPTVHVEEKQVSLPSGVKELNIMSNTPPPRPPKPSYLSEQ... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-Q8BSM5-F1-model_v6.pdb | 10090.ENSMUSP00000041951 | [
"Q61240",
"Q6PCL5"
] | [
"IPR001849",
"IPR011993",
"IPR046355"
] | {"IPR011993": [1, 128], "IPR046355": [1, 594], "IPR001849": [5, 119]} | - Growth factor receptor-bound protein 2
- Tyrosine-protein phosphatase non-receptor type 11 | - IPR001849: Pleckstrin homology domain (domain) [5-119]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-128]
- IPR046355: GRB2-associated-binding protein 1-4-like (family) [1-594] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure developm... |
P41891 | Protein gar2 | Helps the assembly of pre-ribosomal particles containing 18S rRNA | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | 500 | Nucleus, nucleolus | MAKKDKTSVKKSVKETASKKGAIEKPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAKRASSPEPSKKSVKKQKKSKKKEESSSESESESSSSESESSSSESESSSSESESSSSESSSSESEEEVIVKTEEKKESSSESSSSSESEEEEEAVVKIEEKKESSSDSSSESSSSESESESSSSESEEEEEVVEKTEEKKEGSSESSSDSESSSDSSSESGDSDSSSDSESESSSEDEKKRKAEPASEERPAKITKPSQDSNETCTVFVGRLSWNVDDQWLGQEFEEYGTIVGARVIMDGQSGRSKGYGYVDFETPEAAKAA... | [
"GO:0003674",
"GO:0003676",
"GO:0003723",
"GO:0005488",
"GO:0140104",
"GO:0140597",
"GO:0140713"
] | [] | [
"GO:0003674",
"GO:0003676",
"GO:0003723",
"GO:0005488",
"GO:0140104",
"GO:0140597",
"GO:0140713"
] | [] | AF-P41891-F1-model_v6.pdb | 284812.P41891 | [
"Q9URX7",
"O14053",
"O36021",
"Q10475",
"Q9URX9",
"O94659",
"P15398",
"Q09713",
"P87115",
"O14360",
"Q9C1X1",
"Q9UT91",
"Q9UUG1",
"Q9P7M5",
"Q10202",
"Q9UUL8",
"Q06975",
"O43036",
"Q7LKZ9",
"O14086",
"O14007",
"Q9UTX6",
"O13835",
"Q9P7H0",
"Q7Z996",
"O94514",
"O60... | [
"IPR050886",
"IPR035979",
"IPR034276",
"IPR000504",
"IPR012677"
] | {"IPR012677": [185, 482], "IPR035979": [254, 474], "IPR050886": [232, 353], "IPR000504": [263, 443], "IPR034276": [368, 439]} | - rRNA 2'-O-methyltransferase fibrillarin
- Nucleolar protein 56
- H/ACA ribonucleoprotein complex subunit gar1
- H/ACA ribonucleoprotein complex subunit cbf5
- Protein pxr1
- Pre-rRNA-processing protein esf2
- Nucleolar protein 58
- ATP-dependent RNA helicase dbp2
- Ribosome production factor 2 homolog
- GTPase grn1 | - IPR050886: RNA-binding_regulatory_proteins (family) [232-353]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [254-474]
- IPR034276: Gar2, RNA recognition motif 2 (domain) [368-439]
- IPR000504: RNA recognition motif domain (domain) [263-443]
- IPR012677: Nucleotide-binding alpha-beta plait domai... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process),... |
P0C8J6 | D-tagatose-1,6-bisphosphate aldolase subunit GatY | Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is inv... | Escherichia coli (strain K12) | 284 | null | MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA | [
"GO:0005975",
"GO:0006059",
"GO:0006066",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016052",
"GO:0019402",
"GO:0019404",
"GO:0019405",
"GO:0019407",
"GO:0019751",
"GO:0044238",
"GO:0044281",
"GO:0044282",
"GO:0046164",
"GO:0046174"
] | [
"GO:0005975",
"GO:0006059",
"GO:0006066",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016052",
"GO:0019402",
"GO:0019404",
"GO:0019405",
"GO:0019407",
"GO:0019751",
"GO:0044238",
"GO:0044281",
"GO:0044282",
"GO:0046164",
"GO:0046174"
] | [] | [] | AF-P0C8J6-F1-model_v6.pdb | 511145.b2096 | [
"P97243",
"Q2M8L2",
"P0A9B2",
"Q2M977",
"P76412",
"P78260",
"P76414",
"Q2M973",
"Q2M6G1",
"Q2M783",
"P10177",
"Q6BF16",
"Q2M9R6",
"P76410",
"Q46888"
] | [
"IPR023955",
"IPR050246",
"IPR011288",
"IPR000771",
"IPR013785"
] | {"IPR013785": [1, 284], "IPR000771": [1, 284], "IPR023955": [1, 284], "IPR011288": [3, 284], "IPR050246": [4, 278]} | - D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- PTS system galactitol-specific EIIA component
- D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
- D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
- ATP-dependent 6-phosphofructokinase isozyme 1
- PTS system gal... | - IPR023955: D-tagatose-bisphosphate aldolase, class II, subunit GatY (family) [1-284]
- IPR050246: Class II Fructose-bisphosphate Aldolase (family) [4-278]
- IPR011288: D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY (family) [3-284]
- IPR000771: Fructose-bisphosphate aldolase, class-II (family) [1-284]
... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0043169 (cation binding), GO:0016832 (aldehyde-lyase activity), GO:0046872 (... |
Q92616 | Stalled ribosome sensor GCN1 | Ribosome collision sensor that plays a key role in the RNF14- RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes. Directly binds to the ribosome and acts as a ... | Homo sapiens (Human) | 2,671 | Cytoplasm. Note=Associates with ribosomes in undifferentiated neuroblastoma cells and increases after neuronal differentiation | MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWTCLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPKYLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIVKGLAGHLKSNSPRLMDEAVL... | [
"GO:0000209",
"GO:0006412",
"GO:0006414",
"GO:0006508",
"GO:0006511",
"GO:0006950",
"GO:0006996",
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016567",
"GO:0019538"... | [
"GO:0000209",
"GO:0006412",
"GO:0006414",
"GO:0006508",
"GO:0006511",
"GO:0006950",
"GO:0006996",
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016567",
"GO:0019538"... | [] | [] | AF-Q92616-F1-model_v6.pdb | 9606.ENSP00000300648 | [
"Q9Y3U8",
"Q8NCN9",
"Q8WW97",
"Q5T8U4",
"P46776",
"Q5TZC0",
"Q9BPX0",
"P32969",
"Q8WTZ6",
"P63220",
"Q6IBM9",
"Q7Z3D1",
"Q9Y674",
"Q9BTJ1",
"Q9H3F4",
"Q96EG8",
"Q7Z6E4",
"P62249",
"Q76M58",
"Q8TDA5",
"Q6IPF8",
"Q9BUZ2",
"Q86VC0",
"Q6FH47",
"Q9H2E5",
"Q6PEK3",
"P39... | [
"IPR057546",
"IPR016024",
"IPR011989",
"IPR034085",
"IPR021133",
"IPR056810"
] | {"IPR011989": [133, 2664], "IPR016024": [148, 2637], "IPR056810": [220, 353], "IPR034085": [1365, 1598], "IPR057546": [2076, 2258], "IPR021133": [1616, 2043]} | - eIF-2-alpha kinase GCN2
- ATP-binding cassette sub-family F member 3
- Developmentally-regulated GTP-binding protein 2
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS10
- Larg... | - IPR057546: Stalled ribosome sensor GCN1-like, HEAT repeats region (domain) [2076-2258]
- IPR016024: Armadillo-type fold (homologous_superfamily) [148-2637]
- IPR011989: Armadillo-like helical (homologous_superfamily) [133-2664]
- IPR034085: TOG domain (domain) [1365-1598]
- IPR021133: HEAT, type 2 (repeat) [1616-2043... | Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0090079 (translation regulator activity, nucleic acid binding), GO:0005515 (protein binding), GO:00036... |
Q5ABR2 | Mitochondrial Rho GTPase 1 | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 716 | Mitochondrion outer membrane; Single-pass type IV membrane protein | MSPDAIRVVVCGDDAVGKSSLITSLIKETIIEPQTNNVLPPITISRNDYIESSQEYLNDQDHHHHHQSSPSTMKNKRKHNNKRERERERESSINNVQPNEISEYIPNITTIIDTSSSDMTNLQKELKRADVIWLVYSDHYTYERISLHWMPLFRSMGVNLPIILCANKSDLFPKSKSNLKSTNSDEFVPLINEFKEIEAGVRCSAKNNYNVVEAFYLCQRAVTHPISPIFDAKEGNLKPGAIKPLKRIFWLSDTDQDGYLNFEELSELHKKCFGIEASKSDYEEIVNLIDQKILPSYNTTIETQTPPQQQHLATSAGTPN... | [
"GO:0006996",
"GO:0007005",
"GO:0008150",
"GO:0009987",
"GO:0010570",
"GO:0016043",
"GO:0040008",
"GO:0050789",
"GO:0050794",
"GO:0051128",
"GO:0060237",
"GO:0065007",
"GO:0071840",
"GO:1900428",
"GO:1903338"
] | [
"GO:0006996",
"GO:0007005",
"GO:0008150",
"GO:0009987",
"GO:0010570",
"GO:0016043",
"GO:0040008",
"GO:0050789",
"GO:0050794",
"GO:0051128",
"GO:0060237",
"GO:0065007",
"GO:0071840",
"GO:1900428",
"GO:1903338"
] | [] | [] | AF-Q5ABR2-F1-model_v6.pdb | 237561.Q5ABR2 | [
"Q5AH14",
"A0A1D8PKC4",
"Q59MC8",
"Q5AKW2",
"Q59LM9",
"A0A1D8PRQ6",
"Q59LZ5",
"Q59VU7",
"Q59P94",
"Q5AIA0",
"Q59SI5",
"Q5ALP4",
"Q5AMQ3",
"Q59S52",
"A0A1D8PQY9",
"Q5AND0",
"Q59LZ9"
] | [
"IPR013567",
"IPR001806",
"IPR052266",
"IPR013566",
"IPR027417",
"IPR011992",
"IPR021181",
"IPR020860",
"IPR018247",
"IPR002048"
] | {"IPR027417": [4, 673], "IPR011992": [220, 456], "IPR021181": [4, 709], "IPR001806": [8, 667], "IPR052266": [193, 597], "IPR020860": [3, 671], "IPR002048": [240, 423], "IPR013567": [323, 389], "IPR013566": [427, 496], "IPR018247": [253, 265]} | - Mitochondrial distribution and morphology protein 12
- Mitochondrial distribution and morphology protein 10
- Rga2p
- Mitofusin
- Mitochondrial import receptor subunit TOM20
- Mitochondrial distribution and morphology protein 34
- Mitochondrial outer membrane protein porin
- SAM complex subunit
- Maintenance of mitoc... | - IPR013567: EF hand associated, type-2 (domain) [323-389]
- IPR001806: Small GTPase (family) [8-667]
- IPR052266: Mitochondrial Rho GTPase/EF-hand domain-containing protein (family) [193-597]
- IPR013566: Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 (domain) [427-496]
- IPR027417: P-loop containing nucleos... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), ... |
P25596 | Glutathione exchanger 1 | Proton/glutathione antiporter that imports glutathione from the vacuole and exports it through the plasma membrane. Involved in resistance to oxidative stress and modulation of the PKA pathway | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | 615 | Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein | MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFF... | [
"GO:0003674",
"GO:0005215",
"GO:0022857",
"GO:0034634",
"GO:0035673",
"GO:0042887",
"GO:0042937",
"GO:0072349",
"GO:1901682"
] | [] | [
"GO:0003674",
"GO:0005215",
"GO:0022857",
"GO:0034634",
"GO:0035673",
"GO:0042887",
"GO:0042937",
"GO:0072349",
"GO:1901682"
] | [] | AF-P25596-F1-model_v6.pdb | 4932.YCL073C | [
"P25594"
] | [
"IPR036259",
"IPR011701"
] | {"IPR036259": [54, 573], "IPR011701": [67, 490]} | - Vacuolar basic amino acid transporter 3 | - IPR036259: MFS transporter superfamily (homologous_superfamily) [54-573]
- IPR011701: Major facilitator superfamily (family) [67-490] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015343 (siderophore-iron transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization... |
Q91VC9 | Growth hormone-inducible transmembrane protein | Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion (By similarity). Also functions as an electroneutral mitochondrial proton/potassium exchanger. Required for the mitochondrial tubul... | Mus musculus (Mouse) | 346 | Mitochondrion inner membrane; Multi-pass membrane protein | MLAARLVCLRTLPSRVFQPTFITKASPLVKNSITKNQWLVTPSREYATKTRIRTHRGKTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGMSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSALAVARTPALMNFMMTGSWVTIGATFAAMIGAGMLVHSISYEQSPGPKHLAWMLHSGVMGAVVAPLTILGGPLLLRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFASSLGSMFLPPTSVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEITPMYGAQKYDPINSM... | [
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006813",
"GO:0006996",
"GO:0007005",
"GO:0007006",
"GO:0007007",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0030001",
"GO:0034220",
"GO:0051179",
"GO:0051234",
"GO:0055085",
"GO:0061024",
"GO:0071805",
"GO:0071840",
"GO:0098655"... | [
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006813",
"GO:0006996",
"GO:0007005",
"GO:0007006",
"GO:0007007",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0030001",
"GO:0034220",
"GO:0051179",
"GO:0051234",
"GO:0055085",
"GO:0061024",
"GO:0071805",
"GO:0071840",
"GO:0098655"... | [] | [] | AF-Q91VC9-F1-model_v6.pdb | 10090.ENSMUSP00000129712 | [
"Q9D2C7",
"Q9Z1Z4",
"Q9DB77",
"Q99KB6"
] | [
"IPR006214",
"IPR035871"
] | {"IPR006214": [114, 338], "IPR035871": [82, 345]} | - Cytochrome b-c1 complex subunit 2, mitochondrial
- Protein lifeguard 3
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- Bax inhibitor 1 | - IPR006214: Bax inhibitor 1-related (family) [114-338]
- IPR035871: Growth hormone-inducible transmembrane protein (domain) [82-345] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biol... |
A6M9B7 | O-antigen biosynthesis glycosyltransferase WclY | Involved in the assembly of the O-repeating unit during O- antigen biosynthesis. Glucosyltransferase accountable for the alpha-D- Glc-1,4-beta-D-Gal linkage within the O-antigen. Transfers alpha-1,4-Glc to the Gal moiety of a specific Gal-beta1-3GalNAc-alpha-OPO3-PO3-phenoxyundecyl (Gal-beta1- 3GalNAc-PP-PhU) synthetic... | Escherichia coli | 353 | Membrane; Single-pass membrane protein | MKIAYVVSSKKKCGPNIVILNIVKELANKHEMEIFFLDESDDDVFECVNVKSTQIKKASDLKEHLKRFDIIHSSGIRPDALVVLCKVIYRVKCKIITTIHNYVFQDLYYSYGLVKSLIGGLLWCSIWLFFDKLVILSKNADNYYWFLPSAKKNIIYNGIDDNDCLQNKKCNYRKEFNIPDDGILAGSCANLTKRKGIDLVIQTLTKEHKIYYIVAGNGIEKHNLINLVKARKLHERVYFIDFLDEPESFMSQLDVFLMPSRSEGFGLTVLESTKLGIPVITSNIPIFMELFDQMCLTFDIKNPSTLIDVITYAKKNRLHL... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0046527"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009274",
"GO:0009276",
"GO:0030312",
"GO:0030313",
"GO:0071944",
"GO:0110165"
] | AF-A6M9B7-F1-model_v6.pdb | null | null | [
"IPR028098",
"IPR001296"
] | {"IPR028098": [14, 161], "IPR001296": [171, 319]} | - IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [14-161]
- IPR001296: Glycosyl transferase, family 1 (domain) [171-319] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:000815... | |
P0AEQ3 | Glutamine-binding periplasmic protein | Involved in a glutamine-transport system GlnHPQ | Escherichia coli (strain K12) | 248 | Periplasm | MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWFGTEPK | [
"GO:0006810",
"GO:0006865",
"GO:0006868",
"GO:0008150",
"GO:0015711",
"GO:0015804",
"GO:0015849",
"GO:0046942",
"GO:0051179",
"GO:0051234",
"GO:0071705",
"GO:0003674",
"GO:0005488",
"GO:0031406",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177",
"GO:0070406"
] | [
"GO:0006810",
"GO:0006865",
"GO:0006868",
"GO:0008150",
"GO:0015711",
"GO:0015804",
"GO:0015849",
"GO:0046942",
"GO:0051179",
"GO:0051234",
"GO:0071705"
] | [
"GO:0003674",
"GO:0005488",
"GO:0031406",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177",
"GO:0070406"
] | [] | AF-P0AEQ3-F1-model_v6.pdb | 511145.b0811 | [
"Q2M8U5",
"P41076",
"P77763",
"Q2MAS9",
"Q9R7T3",
"P77355",
"P41074",
"P77311",
"P76936",
"P41075",
"P77290",
"P76314",
"P77476",
"Q2M869",
"P77635",
"Q47343",
"P77299",
"Q2M8U4",
"Q2M8G7",
"P10346",
"P76315",
"P76825",
"Q2M7K6"
] | [
"IPR044132",
"IPR001638",
"IPR018313",
"IPR001320"
] | {"IPR001320": [26, 245], "IPR001638": [26, 246], "IPR044132": [26, 244], "IPR018313": [48, 61]} | - Glutamine transport ATP-binding protein GlnQ
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamate/aspartate import permease protein GltK
- Glutamate/aspart... | - IPR044132: Glutamine-binding periplasmic protein GlnH, type 2 periplasmic binding protein fold (domain) [26-244]
- IPR001638: Solute-binding protein family 3/N-terminal domain of MltF (domain) [26-246]
- IPR018313: Solute-binding protein family 3, conserved site (conserved_site) [48-61]
- IPR001320: Ionotropic glutam... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0036094 (small molecule binding), GO:0022857 (transmembrane transporter activity), GO:0043167 (ion binding), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0005342 (organic acid tra... |
P0AC55 | Nitrogen regulatory protein GlnK | Involved in the regulation of nitrogen metabolism. Regulates the activity of its targets by protein-protein interaction in response to the nitrogen status of the cell. Involved in the regulation of the ammonium transporter AmtB so as to optimize ammonium uptake under all growth conditions. In nitrogen- limited conditio... | Escherichia coli (strain K12) | 112 | Cytoplasm. Cell inner membrane. Note=During nitrogen limitation, GlnK is predominantly in its fully uridylylated state in the cytoplasmic fraction. In response to nitrogen shock, GlnK is deuridylylated rapidly and associates tightly with AmtB in the inner membrane | MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAELYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRIRTGEADEAAL | [
"GO:0006808",
"GO:0008150",
"GO:0032107",
"GO:0032109",
"GO:0045848",
"GO:0048518",
"GO:0048583",
"GO:0048584",
"GO:0050789",
"GO:0065007"
] | [
"GO:0006808",
"GO:0008150",
"GO:0032107",
"GO:0032109",
"GO:0045848",
"GO:0048518",
"GO:0048583",
"GO:0048584",
"GO:0050789",
"GO:0065007"
] | [] | [] | AF-P0AC55-F1-model_v6.pdb | 511145.b0450 | [
"Q2M900",
"Q2M8G7",
"Q47082",
"Q2M8G5",
"Q2M9F2",
"P0A9Z1",
"Q2M8G6",
"Q2MCG1",
"Q2MBX5"
] | [
"IPR011322",
"IPR017918",
"IPR002332",
"IPR015867",
"IPR002187"
] | {"IPR011322": [1, 112], "IPR015867": [1, 112], "IPR002187": [1, 112], "IPR017918": [83, 96], "IPR002332": [46, 51]} | - Ammonium transporter AmtB
- Sensory histidine kinase/phosphatase NtrB
- Bifunctional uridylyltransferase/uridylyl-removing enzyme
- Nitrogen assimilation regulatory protein nac
- DNA-binding transcriptional regulator NtrC
- Nitrogen regulatory protein P-II 1
- Glutamine synthetase
- Bifunctional glutamine synthetase ... | - IPR011322: Nitrogen regulatory PII-like, alpha/beta (homologous_superfamily) [1-112]
- IPR017918: Nitrogen regulatory protein PII, conserved site (conserved_site) [83-96]
- IPR002332: Nitrogen regulatory protein P-II, urydylation site (ptm) [46-51]
- IPR015867: Nitrogen regulatory protein PII/ATP phosphoribosyltransf... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048583 (regulation of resp... |
P0ACL0 | Glycerol-3-phosphate regulon repressor | Repressor of the glycerol-3-phosphate regulon | Escherichia coli (strain K12) | 252 | null | MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELAEQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010605",
"GO:0019219",
"GO:0019222",
"GO:0045892",
"GO:0045934",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0051253",
"GO:0060255"... | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010605",
"GO:0019219",
"GO:0019222",
"GO:0045892",
"GO:0045934",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0051253",
"GO:0060255"... | [] | [] | AF-P0ACL0-F1-model_v6.pdb | null | null | [
"IPR037171",
"IPR036388",
"IPR036390",
"IPR018356",
"IPR001034",
"IPR014036",
"IPR050313"
] | {"IPR036388": [1, 57], "IPR036390": [3, 76], "IPR037171": [73, 233], "IPR050313": [1, 250], "IPR001034": [3, 61], "IPR014036": [74, 231], "IPR018356": [6, 40]} | - IPR037171: NagB/RpiA transferase-like (homologous_superfamily) [73-233]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [1-57]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [3-76]
- IPR018356: Transcription regulator, HTH DeoR-type, conserved ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (re... | |
O93430 | Glycine receptor subunit alphaZ1 | Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity) | Danio rerio (Zebrafish) (Brachydanio rerio) | 444 | Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Perikaryon. Cell projection, dendrite. Cell membrane; Multi-pass membrane protein | MFALGIYLWETIVFFSLAASQQAAARKAASPMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS... | [
"GO:0005575",
"GO:0016020",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0016020",
"GO:0110165"
] | AF-O93430-F1-model_v6.pdb | 7955.ENSDARP00000047679 | [
"Q6DC22",
"A0A0R4INA6",
"D3KYL2",
"Q5W8I5"
] | [
"IPR006202",
"IPR018000",
"IPR008128",
"IPR006028",
"IPR006201",
"IPR006029",
"IPR038050",
"IPR036734",
"IPR036719",
"IPR008127"
] | {"IPR036734": [26, 243], "IPR038050": [242, 444], "IPR036719": [244, 440], "IPR008128": [4, 389], "IPR006201": [7, 433], "IPR008127": [31, 339], "IPR006028": [247, 433], "IPR006202": [37, 244], "IPR006029": [251, 346], "IPR018000": [162, 176]} | - Gephyrin
- Gephyrin
- Transporter
- Glycine receptor subunit beta | - IPR006202: Neurotransmitter-gated ion-channel ligand-binding domain (domain) [37-244]
- IPR018000: Neurotransmitter-gated ion-channel, conserved site (conserved_site) [162-176]
- IPR008128: Glycine receptor alpha1 (family) [4-389]
- IPR006028: Gamma-aminobutyric acid A receptor/Glycine receptor alpha (family) [247-43... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0036094 (small molecule binding), GO:0022857 (transmembrane transporter activity), GO:0043167 (ion binding), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0043168 (anion binding), G... |
Q61606 | Glucagon receptor | G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes... | Mus musculus (Mouse) | 485 | Cell membrane; Multi-pass membrane protein. Note=Is rapidly internalized after ligand-binding | MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNASQCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVFLALLINF... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q61606-F1-model_v6.pdb | 10090.ENSMUSP00000026119 | [
"P62874",
"Q9TS47",
"P01326",
"P62880",
"Q9D907",
"Q3U514",
"Q9D887",
"Q3UFE9",
"Q6PFF5",
"Q9JHX8",
"Q9Z1N8"
] | [
"IPR036445",
"IPR003290",
"IPR003291",
"IPR050332",
"IPR017981",
"IPR001879",
"IPR017983",
"IPR000832"
] | {"IPR036445": [15, 150], "IPR003290": [12, 384], "IPR050332": [13, 434], "IPR003291": [18, 484], "IPR000832": [141, 404], "IPR001879": [43, 131], "IPR017981": [142, 405], "IPR017983": [59, 408]} | - Pro-glucagon
- Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
- Guanine nucleotide-binding protein G(q) subunit alpha
- Gastric inhibitory polypeptide
- Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
- Guanine n... | - IPR036445: GPCR family 2, extracellular hormone receptor domain superfamily (homologous_superfamily) [15-150]
- IPR003290: GPCR, family 2, glucagon-like peptide-1/glucagon receptor (family) [12-384]
- IPR003291: GPCR, family 2, glucagon receptor (family) [18-484]
- IPR050332: G-protein coupled receptor 2 (family) [13... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-... |
P55095 | Pro-glucagon | [Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyp... | Mus musculus (Mouse) | 180 | Secreted | MKTIYFVAGLLIMLVQGSWQHALQDTEENPRSFPASQTEAHEDPDEMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIAEELGRRHADGSFSDEMSTILDNLATRDFINWLIQTKITDKK | [
"GO:0003674",
"GO:0005102",
"GO:0005488",
"GO:0005515",
"GO:0030545",
"GO:0030546",
"GO:0048018",
"GO:0098772",
"GO:0140677"
] | [] | [
"GO:0003674",
"GO:0005102",
"GO:0005488",
"GO:0005515",
"GO:0030545",
"GO:0030546",
"GO:0048018",
"GO:0098772",
"GO:0140677"
] | [] | AF-P55095-F1-model_v6.pdb | 10090.ENSMUSP00000099794 | [
"Q00073",
"P34971",
"Q3ZB03",
"P70661",
"Q9D220",
"P70205",
"O70176",
"Q8K0B5",
"Q9DC68",
"Q9R1C8",
"Q8R1I2",
"Q811R8",
"Q60613",
"Q8K3T5",
"Q9R091",
"P16043",
"Q9TS47",
"Q01147",
"Q8VCK6",
"Q60643",
"Q3V3I2",
"P97321",
"P97750",
"P60041",
"Q9EPS2",
"Q80SS6",
"Q9C... | [
"IPR015550",
"IPR000532"
] | {"IPR015550": [1, 180], "IPR000532": [52, 172]} | - Glucagon receptor
- Glucagon-like peptide 1 receptor
- Gastric inhibitory polypeptide receptor
- Glucagon-like peptide 2 receptor
- Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
- Appetite-regulating hormone
- Dipeptidyl peptidase 4
- Glucose-dependent insulinotropic receptor
- Vasoactive intest... | - IPR015550: Glucagon (family) [1-180]
- IPR000532: Glucagon/GIP/secretin/VIP (domain) [52-172] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050... |
O93806 | Glucosamine 6-phosphate N-acetyltransferase | null | Candida albicans (Yeast) | 149 | null | MMLPQGYTFRKLKLTDYDNQYLETLKVLTTVGEISKEDFTELYNHWSSLPSIYHPYVITNASGIVVATGMLFVEKKLIHECGKVGHIEDISVAKSEQGKKLGYYLVTSLTKVAQENDCYKVILDCSPENVGFYEKCGYKDGGVEMVCRF | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-O93806-F1-model_v6.pdb | null | null | [
"IPR000182",
"IPR039143",
"IPR016181"
] | {"IPR016181": [1, 147], "IPR039143": [4, 145], "IPR000182": [7, 149]} | - IPR000182: GNAT domain (domain) [7-149]
- IPR039143: Glucosamine 6-phosphate N-acetyltransferase-like (family) [4-145]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [1-147] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... | |
E3Q1H1 | Glucosamine 6-phosphate N-acetyltransferase | Involved in the biosynthesis of UDP-N-acetyl-alpha-D- glucosamine. Catalyzes the formation of N-acetyl-D-glucosamine 6- phosphate from acetyl-coenzyme A (acetyl-CoA) and D-glucosamine 6- phosphate | Trypanosoma brucei brucei | 147 | Glycosome. Note=Predominantly located in glycosome microbodies in the bloodstream form of T.brucei | MTDIVDLELRVLEESDLSSHLELLGHLTEAPPLSGVELANIADMRRRAGIVTKVFCHQPTGRIVGSASLMIQPKFTRGGRAVGHIEDVVVDPSYRGAGLGKALIMDLCEISRSKGCYKVILDSSEKSLPFYEKLGFRAHERQMRLDL | [
"GO:0006022",
"GO:0006023",
"GO:0006040",
"GO:0006047",
"GO:0006048",
"GO:0006139",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009225",
"GO:0009226",
"GO:0009987",
"GO:0019637",
"GO:0030309",
"GO:0030311",
"GO:0034654"... | [
"GO:0006022",
"GO:0006023",
"GO:0006040",
"GO:0006047",
"GO:0006048",
"GO:0006139",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009225",
"GO:0009226",
"GO:0009987",
"GO:0019637",
"GO:0030309",
"GO:0030311",
"GO:0034654"... | [
"GO:0003674",
"GO:0003824",
"GO:0004343",
"GO:0005488",
"GO:0005515",
"GO:0008080",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005777",
"GO:0020015",
"GO:0042579",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-E3Q1H1-F1-model_v6.pdb | null | null | [
"IPR000182",
"IPR039143",
"IPR016181"
] | {"IPR016181": [6, 144], "IPR039143": [5, 143], "IPR000182": [7, 147]} | - IPR000182: GNAT domain (domain) [7-147]
- IPR039143: Glucosamine 6-phosphate N-acetyltransferase-like (family) [5-143]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [6-144] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... | |
B8QSK0 | O-antigen biosynthesis glycosyltransferase WclY | Involved in the assembly of the O-repeating unit during O- antigen biosynthesis. N- acetylglucosamine transferase accountable for the alpha-D-GlcNAc-1,4- beta-D-Gal linkage within the O-antigen | Escherichia coli | 353 | Membrane; Single-pass membrane protein | MKIAYVVSSKKKCGPNIVILNIVKELANKHEMEIFFLDESDDDVFECVNVKSTQIKKASDLKEHLKRFDIIHSSGIRPDALVVLCKVIYRVKCKIITTIHNYVFQDLYYSYGLVKSLIWGLLWCSIWLFFDKLVILSKNADNYYWFLPSAKKNIIYNGIDDNDCLQNKKCNYRKEFNIPDDGILAGSCANLTKCKGIDLVIQTLTKEHKIYYIVAGDGIEKHNLINLVKARKLHERVYFIDFLDEPESFMSQLDVFLMPSRSEGFGLTVLESTKLGIPVITSNIPIFMELFDQMCLTFDIKNPSTLIDVITYAKKNRLHL... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016757"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009274",
"GO:0009276",
"GO:0030312",
"GO:0030313",
"GO:0071944",
"GO:0110165"
] | AF-B8QSK0-F1-model_v6.pdb | null | null | [
"IPR028098",
"IPR001296"
] | {"IPR028098": [14, 161], "IPR001296": [171, 319]} | - IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [14-161]
- IPR001296: Glycosyl transferase, family 1 (domain) [171-319] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:000815... | |
Q9C666 | GCN5-related N-acetyltransferase 1, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA) and epsilon-lysine acetylation (KA), possibly with a low efficiency or toward specific plastid substrates. Involved in melatonin biosynthesis by catalyzing the formation of N-acetylserotonin (NAS) from serotonin and of melatonin (... | Arabidopsis thaliana (Mouse-ear cress) | 197 | Plastid, chloroplast | MFLGGTISTPPASLRLRSTLNPQNAVTQSSSQATFPAAMQRKPPSYSISDEDLESRGFLLRRTTEGLNLDQLNSVFAAVGFPRRDTAKIEVALQHTDALLWVEYEKTRRPVAFARATGDGVFNAIIWDVVVDPSFQSCGLGKAVMERLIEDLQVKGICNIALYSEPRVLGFYRPLGFVSDPDGIKGMVFIRKQRNKK | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0010817",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0030186",
"GO:0030187",
"GO:0031365",
"GO:0036211",
"GO:0042430",
"GO:0042435",
"GO:0042445"... | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0010817",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0030186",
"GO:0030187",
"GO:0031365",
"GO:0036211",
"GO:0042430",
"GO:0042435",
"GO:0042445"... | [] | [] | AF-Q9C666-F1-model_v6.pdb | 3702.Q9C666 | [
"Q9ZV06",
"Q8S8E7",
"Q9FJ54",
"Q9SMY3",
"A0A1P8B7P8",
"Q8GUT5",
"Q9C7G6",
"Q9SA54",
"Q94AC8",
"Q9T003",
"Q9ZV08",
"Q9LR91",
"Q9C6X3",
"Q8VXY0",
"Q9FKI4",
"Q0WNC8"
] | [
"IPR045039",
"IPR000182",
"IPR016181"
] | {"IPR016181": [68, 180], "IPR045039": [26, 193], "IPR000182": [58, 195]} | - Phenylacetaldehyde synthase
- Acetylserotonin O-methyltransferase
- GCN5-related N-acetyltransferase 10, chloroplastic
- Acyl-CoA N-acyltransferases (NAT) superfamily protein
- GCN5-related N-acetyltransferase 2, chloroplastic
- GCN5-related N-acetyltransferase 5, chloroplastic
- GCN5-related N-acetyltransferase 4, c... | - IPR045039: Acetyltransferase NSI-like (family) [26-193]
- IPR000182: GNAT domain (domain) [58-195]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [68-180] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... |
Q940H2 | GCN5-related N-acetyltransferase 3, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA) and epsilon-lysine acetylation (KA), possibly with a low efficiency or toward specific plastid substrates | Arabidopsis thaliana (Mouse-ear cress) | 237 | Plastid, chloroplast | MGLVGCVGKSSLVSMELRWARRRKSDNAASALPRSIPIYISTLKKDINLEELRNLYSLCNHSCNRLSEKDSNVEKIVDMKKLRRAISRSDVIVSVFCKPQHVDVDDAVLYSEEESLSSSLYTSEFGRQNKDDSFLGDLFQNAVPLTPSNGQLVGFGRAYSDYGLTASIHDLMVLPSLQRMGIGKLIVNRIVRLLTSRDIYDIAALCFEDERPFFKACGFGDDRMGSTTMMFTKSLEA | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [] | [] | AF-Q940H2-F1-model_v6.pdb | null | null | [
"IPR000182",
"IPR039143",
"IPR016181"
] | {"IPR016181": [148, 219], "IPR039143": [41, 231], "IPR000182": [94, 237]} | - IPR000182: GNAT domain (domain) [94-237]
- IPR039143: Glucosamine 6-phosphate N-acetyltransferase-like (family) [41-231]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [148-219] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... | |
Q9LR91 | GCN5-related N-acetyltransferase 5, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a large spectrum of modified N- termini, including methionine, alanine, serine and to a lower extent threonine and valine as substrates, and epsilon-lysine acetylation (KA) | Arabidopsis thaliana (Mouse-ear cress) | 319 | Plastid, chloroplast | MAALSISLAFSVDSLKPTQSTKFGFSSSSHRYPLLYSCKSHRSNLRFAFPPSSVSTATETGEENSKSTGNYAFLEESFRTGRFLSNDELEKLKTLEGFAYFQELESGSMWVRVMRHEEMDSTVHLLAESFGESMLLPSGYQSVLRFLIKQYLIERREVLPHAVTLVGFFRKKVDEFSDDGEEEAVMAGTVEVCLEKRGANASPPSPTPPKESPYICNMTVKEDLRRRGIGWHLLKASEELISQISPSKDVYLHCRMVDEAPFNMYKKAGYEVVKTDTVLVLLMLQRRKHLMRKKLLPLCTNPIVEMVGSDNELTSSANV | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [] | [] | AF-Q9LR91-F1-model_v6.pdb | 3702.Q9LR91 | [
"Q9FKI4",
"Q9C666",
"Q9C6X3",
"Q9ZV08",
"Q94AC8",
"Q9S9M7",
"Q9SA54",
"Q9C7G6",
"Q9ZV06",
"Q8S8E7",
"A0A1P8B7P8",
"Q8GUT5"
] | [
"IPR000182",
"IPR016181"
] | {"IPR016181": [109, 294], "IPR000182": [206, 270]} | - GCN5-related N-acetyltransferase 7, chloroplastic
- GCN5-related N-acetyltransferase 10, chloroplastic
- GCN5-related N-acetyltransferase 8
- GCN5-related N-acetyltransferase 4, chloroplastic
- Acyl-CoA N-acyltransferases (NAT) superfamily protein
- GCN5-related N-acetyltransferase 1, chloroplastic
- GCN5-related N-a... | - IPR000182: GNAT domain (domain) [206-270]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [109-294] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-... |
Q8GUT5 | GCN5-related N-acetyltransferase 6, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a large spectrum of modified N- termini, including methionine, alanine, serine, threonine and to a lower extent valine as substrates, and epsilon-lysine acetylation (KA) | Arabidopsis thaliana (Mouse-ear cress) | 288 | Plastid, chloroplast. Cytoplasm, perinuclear region. Note=Spotted pattern, either associated with chloroplasts or confined within the nuclear envelope | MSTISIHRTETLRITHARSRIFRQRYRRTIPLWKLTINSRSSDTSKKEELSVQISIPPQVDQSRPEGLRFDRLQPPEPEFGHEDRFEFGKFVAREAMLDEEYWTAAWLRAESHWEDRSNERYVDNYKRKFAEQEFNAIKRRCKGMQGQKCSCIVAVKKEEKHIKRSVIKSVVGTLDLSIRYFLQGETFPGEKVKSQLFCSINQEGSNRYGYIANLCVAKSARRQGIACNMLRFAVESARLSGVEQVYVHVHKNNSVAQELYQKTGFKIVETGKFESLDDDTYLLQYTS | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [] | [] | AF-Q8GUT5-F1-model_v6.pdb | 3702.Q8GUT5 | [
"Q9SA54",
"Q9C6X3",
"Q9S9M7",
"A0A1P8B7P8",
"Q8S8E7",
"Q9ZV06",
"Q9C666",
"Q9LR91",
"Q9FKI4",
"Q9ZV08"
] | [
"IPR000182",
"IPR016181"
] | {"IPR016181": [204, 281], "IPR000182": [151, 288]} | - GCN5-related N-acetyltransferase 4, chloroplastic
- Acyl-CoA N-acyltransferases (NAT) superfamily protein
- GCN5-related N-acetyltransferase 9
- GCN5-related N-acetyltransferase 8
- GCN5-related N-acetyltransferase 5, chloroplastic
- GCN5-related N-acetyltransferase 1, chloroplastic
- N-terminal acetyltransferase B c... | - IPR000182: GNAT domain (domain) [151-288]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [204-281] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... |
Q94AC8 | GCN5-related N-acetyltransferase 7, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a large spectrum of modified N- termini, including methionine, alanine, serine, threonine and to a lower extent valine and proline as substrates, and epsilon-lysine acetylation (KA) | Arabidopsis thaliana (Mouse-ear cress) | 274 | Plastid, chloroplast | MAFLCSSLPSSSSIAIFGDPNTDGSSRSYLSIPSLKLRFRPVAASSHICAPAIDKSTFVISESVSEDELWAAACLRVRTFNELNPSAYNIQDHRRYLAEREFEALKERTSGKREGFTRVACINATLPLSQLSSSFEDLCSACKFSDGIEDRVVVGSLDLNQCRWLPDEIAGTKPEGIGVDFARAYLSNVCVAKELHRNGVGYKLIDKSKRVAGEWGITDMYVHVTVDNEAAKSLYMKSGFEQETAEPAWQARYLNRPQRLLLWLALPTSPIMSM | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [] | [] | AF-Q94AC8-F1-model_v6.pdb | 3702.Q94AC8 | [
"Q9S9M7",
"Q9SA54",
"O22268",
"Q9C7G6",
"A0A1P8B7P8",
"Q9ZV06",
"Q8S8E7",
"Q9FKI4",
"Q9C6X3",
"Q9LR91",
"Q9C666",
"Q9ZV08"
] | [
"IPR000182",
"IPR016181"
] | {"IPR016181": [84, 245], "IPR000182": [75, 267]} | - GCN5-related N-acetyltransferase 10, chloroplastic
- Acyl-CoA N-acyltransferases (NAT) superfamily protein
- GCN5-related N-acetyltransferase 4, chloroplastic
- GCN5-related N-acetyltransferase 5, chloroplastic
- GCN5-related N-acetyltransferase 8
- GCN5-related N-acetyltransferase 9
- GCN5-related N-acetyltransferas... | - IPR000182: GNAT domain (domain) [75-267]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [84-245] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... |
Q9C7G6 | GCN5-related N-acetyltransferase 10, chloroplastic | Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a preference for leucine, methionine, serine, valine and to a lower extent threonine and alanine as substrates (can also use glycine), and epsilon-lysine acetylation (KA) of several plastid proteins | Arabidopsis thaliana (Mouse-ear cress) | 256 | Plastid, chloroplast | MGHLPQSLYSAAGPKFPYPGSSGLGVDQRKLTWSRFPVFLRCASTESLTSLTQNNAAEIELKYLVSQHGWDVRRLNRDDEDEIRRVSLVQAEAFHIPLALFDDFFFMFFQAEVLSALLYKLKNSPPDRYACLVAEQTSETETLSSSSVVGVVDVTAQTESSVLRYFPGVEEYLYVSGLAVSKSQRRKKMASTLLKACDVLCYLWGFKLLALRAYEDDAAARNLYSNAGYSVVETDPLWTSTWIGRKRRVLMSKRFS | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [
"GO:0006473",
"GO:0006474",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0018193",
"GO:0018205",
"GO:0018394",
"GO:0019538",
"GO:0031365",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043543",
"GO:0044238",
"GO:0051604"
] | [] | [] | AF-Q9C7G6-F1-model_v6.pdb | 3702.Q9C7G6 | [
"Q8S8E7",
"Q9ZV06",
"A0A1P8B7P8",
"Q9SA54",
"Q94AC8",
"Q9S9M7",
"Q9ZV08",
"Q9LR91",
"Q9C666",
"Q9C6X3",
"Q9FKI4"
] | [
"IPR000182",
"IPR051556",
"IPR016181"
] | {"IPR016181": [72, 254], "IPR051556": [75, 255], "IPR000182": [106, 256]} | - Acyl-CoA N-acyltransferases (NAT) superfamily protein
- GCN5-related N-acetyltransferase 7, chloroplastic
- GCN5-related N-acetyltransferase 1, chloroplastic
- GCN5-related N-acetyltransferase 4, chloroplastic
- GCN5-related N-acetyltransferase 5, chloroplastic
- GCN5-related N-acetyltransferase 9
- GCN5-related N-ac... | - IPR000182: GNAT domain (domain) [106-256]
- IPR051556: N-terminal and lysine N-acetyltransferase (family) [75-255]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [72-254] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-... |
Q8SZ63 | Golgin-84 | May be involved in maintaining Golgi structure and in intra- Golgi transport | Drosophila melanogaster (Fruit fly) | 516 | Golgi apparatus membrane; Single- pass type IV membrane protein | MSSWITGLADKAENILNKLDQNAATALQTENATGSADPMRRSMTSSTQSLSTSLKSTLSPVRRSGANSSSSVKSDGGVSVVTKDMRQKMTTSASFSNSPDISANSMDTNELAAFKIALNEITAERDELRLRLEDLNNETEKFDLHQHTQVLEALVKSLSEERDKAVHDYNEAQAANMAYVHSISELETNLAKLQQEYISAAHKLQMQTKETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQARE... | [
"GO:0006810",
"GO:0006891",
"GO:0006903",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051640",
"GO:0051641",
"GO:0051648",
"GO:0051649",
"GO:0051650",
"GO:0051656",
"GO:0071840",
"GO:0099022",
"GO:0099041",
"GO:0003674"... | [
"GO:0006810",
"GO:0006891",
"GO:0006903",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051640",
"GO:0051641",
"GO:0051648",
"GO:0051649",
"GO:0051650",
"GO:0051656",
"GO:0071840",
"GO:0099022",
"GO:0099041"
] | [
"GO:0003674",
"GO:0038024"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005794",
"GO:0005801",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0033106",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098588",
"GO:0110165"
] | AF-Q8SZ63-F1-model_v6.pdb | 7227.FBpp0084013 | [
"A0A4D6K5M0",
"Q9VHE3",
"Q9VAD6",
"Q9W289",
"Q9VKH0",
"Q9VW57"
] | [
"IPR019177"
] | {"IPR019177": [211, 515]} | - Golgi microtubule-associated protein, isoform D
- Grasp65
- Conserved oligomeric Golgi complex subunit 7
- GH05665p
- Golgi matrix protein 130 kD
- Conserved oligomeric Golgi complex subunit 8 | - IPR019177: Golgin subfamily A member 5 (family) [211-515] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO... |
Q54KV6 | Guanine nucleotide-binding protein alpha-3 subunit | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-3 plays a role in development. G alpha-3 mutants fail to aggregate | Dictyostelium discoideum (Social amoeba) | 570 | null | MDFNPVPPPRETLRAYLSKKGHVVKNWKLRLFVLKPGSSYMEYFVDETKEQQHLPQGRVPLYGTRVMEYVYNSNNNPREFCLSVETENKNWIISTGSKAQQLEWIEAIKHAIESAVETDEIKLQKHKSIEKQLQLDGKNKNKIPVLKLLLLGTGESGKSTVVKQMKILHHKGFSKEEEEFYRNLIYINLLDGMALLIHVIKENNIEIPQETLSAIKNYSSWYRVYIEKRNKNGIRNNPIGSMIPISILNNNKDNNNSNSSSLKNNSGGSSSSELDKKMTHLSLDGSTCINSNSASPNGPSSSTTTSTINTHNRSNSDGSS... | [
"GO:0003674",
"GO:0008603",
"GO:0019207",
"GO:0019887",
"GO:0030234",
"GO:0098772"
] | [] | [
"GO:0003674",
"GO:0008603",
"GO:0019207",
"GO:0019887",
"GO:0030234",
"GO:0098772"
] | [] | AF-Q54KV6-F1-model_v6.pdb | 44689.Q54KV6 | [
"Q54ZV7",
"Q54MC6"
] | [
"IPR011993",
"IPR011025",
"IPR001849",
"IPR027417",
"IPR001019"
] | {"IPR011993": [10, 119], "IPR027417": [146, 566], "IPR011025": [173, 393], "IPR001019": [118, 570], "IPR001849": [10, 115]} | - Latrophilin receptor-like protein A
- Guanine nucleotide-binding protein subunit beta | - IPR011993: PH-like domain superfamily (homologous_superfamily) [10-119]
- IPR011025: G protein alpha subunit, helical insertion (homologous_superfamily) [173-393]
- IPR001849: Pleckstrin homology domain (domain) [10-115]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [146-56... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (re... |
Q8TGB2 | GPI ethanolamine phosphate transferase 2 | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 885 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MSGSLNSRWVVQVSLTIINIIGFLVFLRGFFPSKVVLPGFNSFQDSTKSPFSDQYGNPQFNKFILMVVDAMRSDFCFSDRSNFSFLHQLINQGRALPFTAFSNPPTVTLPRLKGITTGGTPNFLDAILNVADDQDDSQGLHNQDSWVHQFRHSNNKTINFFGDDTWLKLFQDQFTEFEGTNSFFVSDFTEVDNNVTRHLDDQLSSNKWDGLILHYLGLDHIGHKGGPESPYMKPKQIEMDKILQRLYTYVTKNDDTLIVLMGDHGMNEIGNHGGSSPGETSAALSFISPKFNHKGESPLPYNSDYSYHHKISQIDLVPTL... | [
"GO:0006505",
"GO:0006629",
"GO:0006643",
"GO:0006644",
"GO:0006650",
"GO:0006664",
"GO:0006793",
"GO:0006796",
"GO:0006950",
"GO:0008150",
"GO:0008152",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0019637",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [
"GO:0006505",
"GO:0006629",
"GO:0006643",
"GO:0006644",
"GO:0006650",
"GO:0006664",
"GO:0006793",
"GO:0006796",
"GO:0006950",
"GO:0008150",
"GO:0008152",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0019637",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [] | [] | AF-Q8TGB2-F1-model_v6.pdb | 237561.Q8TGB2 | [
"Q5A302",
"Q5A3M6",
"Q5AFT2",
"Q5A0L9"
] | [
"IPR037674",
"IPR045687",
"IPR017850",
"IPR039527",
"IPR002591"
] | {"IPR017850": [61, 349], "IPR039527": [5, 368], "IPR002591": [64, 269], "IPR037674": [57, 336], "IPR045687": [406, 882]} | - Glycosylphosphatidylinositol anchor biosynthesis protein 11
- Endoplasmic reticulum vesicle protein 25
- GPI mannosyltransferase 4
- GPI ethanolamine phosphate transferase 1 | - IPR037674: GPI ethanolamine phosphate transferase 2, N-terminal (domain) [57-336]
- IPR045687: GPI ethanolamine phosphate transferase 2, C-terminal (domain) [406-882]
- IPR017850: Alkaline-phosphatase-like, core domain superfamily (homologous_superfamily) [61-349]
- IPR039527: GPI ethanolamine phosphate transferase 2... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016780 (phosphotransferase activity, for other substituted phosphate groups)
Biological Process (BP): GO:0008150... |
P62707 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate | Escherichia coli (strain K12) | 250 | null | MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009060",
"GO:0009117",
"GO:0009132"... | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009060",
"GO:0009117",
"GO:0009132"... | [] | [] | AF-P62707-F1-model_v6.pdb | 511145.b0755 | [
"Q2M6S9",
"Q2M9R7",
"Q2M8L5",
"Q60139",
"P0A9B2",
"Q2M8L2",
"Q2MA53",
"P78152",
"P40681",
"P08200",
"Q47633",
"P78231",
"P33570",
"P21599",
"P10177",
"P80218",
"P30148",
"Q2M985",
"Q2M7S6",
"Q2M9R6",
"P15877",
"Q2M5S2",
"Q2MBR4",
"Q2M5T6",
"Q6BF59",
"Q2MAX2"
] | [
"IPR013078",
"IPR001345",
"IPR029033",
"IPR005952"
] | {"IPR029033": [2, 250], "IPR005952": [3, 248], "IPR013078": [5, 230], "IPR001345": [8, 17]} | - Phosphoglycerate kinase
- Enolase
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
- Glucose-6-phosphate isomerase
- Probable phosphoglycerate mutase GpmB
- Triosephosphate isomerase
- Fructose-bisphosphate aldolase class 2
- Fructose-bisphosphate aldolase class 1
- Glucose-6-phosphate 1-dehydrogenase
- ... | - IPR013078: Histidine phosphatase superfamily, clade-1 (family) [5-230]
- IPR001345: Phosphoglycerate/bisphosphoglycerate mutase, active site (active_site) [8-17]
- IPR029033: Histidine phosphatase superfamily (homologous_superfamily) [2-250]
- IPR005952: Phosphoglycerate mutase 1 (family) [3-248] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydr... |
O89100 | GRB2-related adaptor protein 2 | Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc | Mus musculus (Mouse) | 322 | Nucleus. Cytoplasm. Endosome | MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPM... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-O89100-F1-model_v6.pdb | 10090.ENSMUSP00000046532 | [
"Q923E6",
"Q99K62",
"Q62245",
"Q9JLL7",
"P04235",
"O54957",
"Q9D3G3",
"Q9R0C8",
"Q6GSH7",
"Q02384",
"Q8K2A3",
"Q99KG4",
"Q61240",
"Q8CHJ3",
"Q922M0",
"Q6PCL5",
"Q03526",
"Q9Z1S8",
"P22646",
"P70315",
"Q9Z2H3",
"Q9Z1S3",
"Q8CHR3",
"Q9WVP5",
"Q2M4I4",
"Q8C8K9",
"P06... | [
"IPR043539",
"IPR036028",
"IPR001452",
"IPR035646",
"IPR036860",
"IPR000980"
] | {"IPR036028": [3, 319], "IPR036860": [49, 155], "IPR043539": [1, 321], "IPR001452": [1, 322], "IPR000980": [56, 149], "IPR035646": [267, 319]} | - Lymphocyte cytosolic protein 2
- Linker for activation of T-cells family member 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Growth factor receptor-bound protein 2
- Proto-oncogene vav
- SHC-transforming protein 1
- Mitogen-activated protein kinase kinase kinase kinase 1
- Tyrosine-protein ... | - IPR043539: Grb2-like (family) [1-321]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [3-319]
- IPR001452: SH3 domain (domain) [1-322]
- IPR035646: GRAP2, C-terminal SH3 domain (domain) [267-319]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [49-155]
- IPR000980: SH2 domain (domain) [... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (de... |
Q6DGJ1 | Grifin | Binds lactose | Danio rerio (Zebrafish) (Brachydanio rerio) | 139 | null | MTLRFEASCPDGLCPGWSVILKGETPPEASKFEINFLCDRDDRVAFHFNPRFTESDIICNSYMANRWGQEERCNHFPLGVEEPFQIEIYSDNDHFHVYIDKAKVMQYKHRVEDLKTITKLQVVNDVKISSLEITKKLFY | [
"GO:0001654",
"GO:0007275",
"GO:0007423",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0043010",
"GO:0048513",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0150063"
] | [
"GO:0001654",
"GO:0007275",
"GO:0007423",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0043010",
"GO:0048513",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0150063"
] | [] | [] | AF-Q6DGJ1-F1-model_v6.pdb | 7955.ENSDARP00000049686 | [
"A0A140LH34",
"Q29RF4",
"E7F2T9",
"E9QIR4",
"E7F5A4",
"Q504C1",
"R4GEY3",
"A0A140LH24",
"A0A140LGZ1",
"X1WCD4",
"Q0P3Y5",
"A0A140LH63",
"E7F225",
"E7F8J2",
"F1QX64",
"A0A140LH11",
"Q5XTN0",
"A0A140LFZ1",
"B0UXR5",
"E7FGJ9",
"Q52JI7",
"E9QD42",
"E9QFU6",
"E7FAK0"
] | [
"IPR001079",
"IPR013320",
"IPR044156"
] | {"IPR013320": [3, 134], "IPR044156": [4, 133], "IPR001079": [3, 134]} | - WD repeat domain 17
- Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2
- Ankyrin repeat domain 33Ab
- Histone H1
- Histone H1
- Histone H1
- Histone H1
- Histone H1
- Histone H1
- Histone H1 | - IPR001079: Galectin, carbohydrate recognition domain (domain) [3-134]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [3-134]
- IPR044156: Galectin-like (family) [4-133] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding), GO:0070492 (oligosaccharide binding), GO:0048030 (disaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:00325... |
Q54SH8 | Metabotropic glutamate receptor-like protein H | null | Dictyostelium discoideum (Social amoeba) | 764 | Membrane; Multi-pass membrane protein | MKNILKILILILICINKINCLDGDGKQFRMIMLLSANVNDMGFNNMMNQGRIGVSKNLQIEDSRLIVVDGENDTKALVEPILQNEDIDFVICSSQGHTVACKYFADKYLKHPTVKTQFLIRGSGSSTANLIQFNYNFASCNYMSGYFAGLHTKTNKIGFLSPGAPKVNDAWVYAFWLGAKQVNPKIQFFYYNVGAFLNPDASERATNDLLERGCDVIGNTLDDFSSGITIMSKGYRTIGTNGFPQKLIYGEKILYSYAYNWTKLFLPIAMSVKAGITNNTNGYGDFNLDESKNFFNIEYSYGVSTDTINRMNQQITFLKS... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q54SH8-F1-model_v6.pdb | 44689.Q54SH8 | [
"Q54PA5",
"Q5XM24",
"Q55CD6"
] | [
"IPR051530",
"IPR003760",
"IPR017978"
] | {"IPR051530": [1, 750], "IPR003760": [31, 220], "IPR017978": [387, 659]} | - Autocrine proliferation repressor protein A
- Frizzled and smoothened-like protein B
- Frizzled and smoothened-like protein K | - IPR051530: Metabotropic Glutamate/GABA-B Receptor-like (family) [1-750]
- IPR003760: ABC transporter substrate-binding protein PnrA-like (domain) [31-220]
- IPR017978: GPCR family 3, C-terminal (domain) [387-659] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of ... |
Q71PD7 | Histone H2A.V | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chrom... | Danio rerio (Zebrafish) (Brachydanio rerio) | 128 | Nucleus. Chromosome | MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA | [
"GO:0008150",
"GO:0045595",
"GO:0045597",
"GO:0045634",
"GO:0045636",
"GO:0048070",
"GO:0048087",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0050932",
"GO:0050942",
"GO:0051094",
"GO:0065007",
"GO:0120305"
] | [
"GO:0008150",
"GO:0045595",
"GO:0045597",
"GO:0045634",
"GO:0045636",
"GO:0048070",
"GO:0048087",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0050932",
"GO:0050942",
"GO:0051094",
"GO:0065007",
"GO:0120305"
] | [] | [] | AF-Q71PD7-F1-model_v6.pdb | 7955.ENSDARP00000090434 | [
"Q7ZV67",
"Q7ZUY0",
"F1QVP8",
"R4GE02",
"F1RAW8",
"F1QMJ9",
"F1QRV6",
"Q1L8X4",
"B8JMZ3",
"A8E7S8",
null,
"F1R473",
"R4GE15",
"X1WH60",
null,
"Q1L672",
"Q8AWW7",
"Q6DGB4",
"Q1LUC3",
"Q6NYY4",
"Q1LUU4",
"Q9PTP1",
null,
"X1WHF1",
"Q7ZTY4",
"Q6NY34",
"P83571",
"A8K... | [
"IPR009072",
"IPR002119",
"IPR032454",
"IPR007125",
"IPR032458"
] | {"IPR009072": [3, 128], "IPR002119": [5, 125], "IPR007125": [10, 93], "IPR032454": [95, 127], "IPR032458": [24, 30]} | - Histone H2B 3
- RuvB-like 1
- Helicase SRCAP isoform X2
- Peptidyl-prolyl cis-trans isomerase
- AT-rich interactive domain-containing protein 4A
- AT-rich interactive domain-containing protein 4B
- Histone H3.3
- Histone H2A
- YEATS domain-containing protein 4
- RuvB-like 2 | - IPR009072: Histone-fold (homologous_superfamily) [3-128]
- IPR002119: Histone H2A (family) [5-125]
- IPR032454: Histone H2A, C-terminal domain (domain) [95-127]
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [10-93]
- IPR032458: Histone H2A conserved site (conserved_site) [24-30] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048... |
Q54WG6 | Histone H2AX | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl... | Dictyostelium discoideum (Social amoeba) | 154 | Nucleus. Chromosome | MSETKPASSKPAAAAKPKKVIPRVSRTGEPKSKPESRSARAGITFPVSRVDRLLREGRFAPRVESTAPVYLAAVLEYLVFEILELAHNTCSISKKTRITPQHINWAVGNDLELNSLFQHVTIAYGGVLPTPQQSTGEKKKKPSKKAAEGSSQIY | [
"GO:0003674",
"GO:0005198",
"GO:0030527",
"GO:0000785",
"GO:0000786",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0032991",
"GO:0032993",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005198",
"GO:0030527"
] | [
"GO:0000785",
"GO:0000786",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0032991",
"GO:0032993",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q54WG6-F1-model_v6.pdb | 44689.Q54WG6 | [
"Q54MA9",
"Q54I18",
"Q55BN9",
"Q54NC4",
"Q54LP8",
"Q54UC0",
"Q76NW2",
"Q55BP0",
"Q54LA5",
"Q54VR9",
"Q55FF6",
"Q54Z28",
"Q55ED1",
"Q9Y0B7"
] | [
"IPR009072",
"IPR002119",
"IPR007125",
"IPR032454"
] | {"IPR009072": [22, 148], "IPR002119": [22, 142], "IPR007125": [31, 107], "IPR032454": [112, 145]} | - Histone H2B.v3
- Histone H4
- Histone H2A.z
- PWWP domain-containing protein
- Histone H3.3 type c
- Histone H3.3 type a
- ATP-dependent DNA helicase ku70
- Histone H3.3 type b
- Suppressor of Mek1
- Histone H1 | - IPR009072: Histone-fold (homologous_superfamily) [22-148]
- IPR002119: Histone H2A (family) [22-142]
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [31-107]
- IPR032454: Histone H2A, C-terminal domain (domain) [112-145] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chro... |
Q76NW2 | Histone H4 | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | Dictyostelium discoideum (Social amoeba) | 108 | Nucleus. Chromosome | MSSAQSRGGKTGGKVGGKVGAKRHKKTQKEHINGITKPAIRRLARRGGVKRISFPIYEETRNVLRTFLTNVIRDSVAYTEHAGRRTVTAMDVVYALKRQGRTLYGFNS | [
"GO:0003674",
"GO:0005198",
"GO:0030527"
] | [] | [
"GO:0003674",
"GO:0005198",
"GO:0030527"
] | [] | AF-Q76NW2-F1-model_v6.pdb | 44689.Q76NW2 | [
"Q55AQ4",
"Q54S04",
"Q54SX2",
"Q54EH2",
"Q55FP1",
"Q86JJ5",
"Q54R66",
"Q54T85",
"Q54N45",
"Q54SC6",
"Q54BC2",
"Q54DB4",
"Q54RM0",
"Q55G81",
"Q54MH6",
"Q54IH7",
"B0G130",
"Q553Z2",
"Q54LN0",
"Q9Y0C9",
"Q54KI3",
"Q54IZ9",
"Q55BP0",
"Q54HI0",
"Q54WT0",
"Q54I13",
"Q54... | [
"IPR035425",
"IPR001951",
"IPR009072",
"IPR019809"
] | {"IPR009072": [6, 108], "IPR001951": [6, 107], "IPR035425": [40, 101], "IPR019809": [20, 24]} | - Histone H2B.v3
- Probable histone-binding protein rbbD
- Histone H3.3 type c
- Histone H3.3 type a
- Histone H3.3 type b
- Histone chaperone asf1
- PWWP domain-containing protein
- Histone H2A.z
- Histone acetyltransferase type B catalytic subunit DDB_G0274269
- Protein arginine N-methyltransferase 1 | - IPR035425: CENP-T/Histone H4, histone fold (domain) [40-101]
- IPR001951: Histone H4 (family) [6-107]
- IPR009072: Histone-fold (homologous_superfamily) [6-108]
- IPR019809: Histone H4, conserved site (conserved_site) [20-24] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0042221 (response to che... |
A0A7P0TBJ1 | HUWE1-associated protein modifying stress responses 2 | Together with HAPSTR1 plays a central regulatory role in the cellular response to molecular stressors, such as DNA damage, nutrient scarcity, and protein misfolding. Regulates these multiple stress response signaling pathways by stabilizing HAPSTR1, but also independently of HAPSTR1 | Homo sapiens (Human) | 273 | Nucleus | MEEQQKEGEAEVAEHWFSKWERQCLAEAEQEEQLPPELQEEAAAELAGLKSEKQKLWHLFQISATAVAQLYKDSGCQQQGLSMWDPFQNAAMAVTSLYKESGDAHQRSFDLGVQVGHQRRIKDVLEWVKKGRSTIRREDLISFLCGKVPPAPPPPRTPRTPPKPPTGVTSQAVATESSSSVDVDLQPFQEAIALHGLSGAMAGISMRSGDSPQDSGVASSGRRKTSFLEDDLNPFDSEELALHLDSGGIRKRTSAQCSDGITDSPIQKRNRMV | [
"GO:0008150",
"GO:0031647",
"GO:0050821",
"GO:0065007",
"GO:0065008",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899",
"GO:0031625",
"GO:0044389",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [
"GO:0008150",
"GO:0031647",
"GO:0050821",
"GO:0065007",
"GO:0065008"
] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899",
"GO:0031625",
"GO:0044389"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-A0A7P0TBJ1-F1-model_v6.pdb | null | null | [
"IPR029196",
"IPR040308"
] | {"IPR040308": [1, 273], "IPR029196": [21, 271]} | - IPR029196: HUWE1-associated protein modifying stress responses-like (family) [21-271]
- IPR040308: HUWE1-associated protein modifying stress responses (family) [1-273] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (re... | |
Q8H991 | Homeobox protein HAZ1 | Transcriptional repressor involved in the regulation of gibberrelin (GA) signaling. Binds to the 5'-GATC-3' motif of HD16/EL1 promoter. Functions as a positive regulator of GA signaling by suppressing the expression of HD16/EL1, a negative regulator of GA signaling | Oryza sativa subsp. japonica (Rice) | 792 | Nucleus | MDKTTTSDLVLDNDNIGSNAGSAQEPLTTNGKTSGVRNRYKQTVKRGRKGSQISPSKTYPLRSSHSNVRVLRSASKKKNETPIVPTNDNTAVQRVAKKRKRSKPLRPAPSRVLRSTSEKKNKAHNELLNDGAGVQPAEKKRKVGRPPKGGTPKDDYLMIRKRVRYVLNRMNYEQSLIQAYASEGWKGQSLEKIRPEKELERAKVEILRCKSRIREAFRNLDSLLSEGKLDESMFDSAGEISSEDIFCAACGSKDVTLKNDIILCDGICDRGFHQYCLNPPLLAEDIPQGDEGWLCPACDCKIDCIDVLNELQGVKLSIHD... | [
"GO:0001217",
"GO:0003674",
"GO:0003700",
"GO:0140110"
] | [] | [
"GO:0001217",
"GO:0003674",
"GO:0003700",
"GO:0140110"
] | [] | AF-Q8H991-F1-model_v6.pdb | 39947.Q8H991 | [
"Q60DG6",
"Q53WJ1",
"Q9XFF4",
"Q9MVP6",
"Q10RP4",
"B9GDC7",
"A0A0P0XEE7",
"A0A0P0VMP6",
"Q7Y0Y6",
"Q2QYT4",
"Q6ZB59",
"Q0D4V4",
"Q0DY89",
"A0A0P0XPV0",
"Q8S5G9",
"A0A0P0WA41",
"Q0D8F2",
"Q94D35",
"Q6ASS7",
"Q2R2X7",
"Q7Y0Y8",
"Q5NAI9",
"Q5Z608",
"A0A0P0X452",
"A0A0P0X... | [
"IPR011011",
"IPR019786",
"IPR009057",
"IPR001965",
"IPR045876",
"IPR001356",
"IPR013083",
"IPR019787"
] | {"IPR013083": [188, 306], "IPR011011": [236, 304], "IPR009057": [613, 675], "IPR019787": [244, 301], "IPR001965": [246, 299], "IPR045876": [246, 298], "IPR001356": [608, 672], "IPR019786": [247, 298]} | - Probable lysine-specific demethylase SE14
- Lectin
- Lectin
- Os04g0339800 protein
- MRG family protein, putative, expressed
- Os04g0101300 protein
- Os04g0101100 protein
- Os09g0544500 protein
- ARID transcription factor
- Os02g0708600 protein | - IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [236-304]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [247-298]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [613-675]
- IPR001965: Zinc finger, PHD-type (domain) [246-299]
- IPR045876: Pathogenesis-related hom... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Proce... |
P69891 | Hemoglobin subunit gamma-1 | Gamma chains make up the fetal hemoglobin F, in combination with alpha chains | Homo sapiens (Human) | 147 | null | MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH | [
"GO:0003674",
"GO:0005344",
"GO:0140104"
] | [] | [
"GO:0003674",
"GO:0005344",
"GO:0140104"
] | [] | AF-P69891-F1-model_v6.pdb | null | null | [
"IPR050056",
"IPR012292",
"IPR000971",
"IPR002337",
"IPR009050"
] | {"IPR009050": [3, 147], "IPR012292": [3, 147], "IPR050056": [4, 147], "IPR002337": [8, 146], "IPR000971": [3, 147]} | - IPR050056: Hemoglobin and related oxygen transporters (family) [4-147]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [3-147]
- IPR000971: Globin (domain) [3-147]
- IPR002337: Hemoglobin, beta-type (family) [8-146]
- IPR009050: Globin-like superfamily (homologous_superfamily) [3-147] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0015669 (gas transport), GO:0015671 (oxygen transport)
... | |
P0AES9 | Acid stress chaperone HdeA | Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non- specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral p... | Escherichia coli (strain K12) | 110 | Periplasm | MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGEWDKIKKDM | [
"GO:0005575",
"GO:0030288",
"GO:0030313",
"GO:0042597",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0030288",
"GO:0030313",
"GO:0042597",
"GO:0110165"
] | AF-P0AES9-F1-model_v6.pdb | 511145.b3510 | [
"P76877",
"Q2M7H3",
"P76873",
"Q54152",
"Q2M7H0",
"Q2M7H9",
"Q2M7G8",
"Q2M7G9",
"Q2M7H8",
"Q2M7H1",
"Q2M7H4",
"P75758",
"Q2MBU2",
"Q2M7H7"
] | [
"IPR010486",
"IPR024972",
"IPR036831",
"IPR038303"
] | {"IPR038303": [22, 110], "IPR036831": [30, 108], "IPR024972": [1, 107], "IPR010486": [11, 96]} | - Glutamate decarboxylase beta
- Glutamate decarboxylase beta
- Glutamate decarboxylase beta
- Acid stress chaperone HdeB
- Protein HdeD
- Glutamate/gamma-aminobutyrate antiporter
- Glutamate/gamma-aminobutyrate antiporter
- Glutamate decarboxylase alpha
- Transcriptional regulator GadE
- Outer membrane protein Slp | - IPR010486: HNS-dependent expression A/B (family) [11-96]
- IPR024972: HNS-dependent expression A (family) [1-107]
- IPR036831: HNS-dependent expression A superfamily (homologous_superfamily) [30-108]
- IPR038303: HNS-dependent expression A/B superfamily (homologous_superfamily) [22-110] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044183 (protein folding chaperone), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0051087 (chaperone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:000... |
Q76P24 | HD protein homolog | May play a role in microtubule-mediated transport or vesicle function | Dictyostelium discoideum (Social amoeba) | 3,095 | Cytoplasm. Nucleus | MDLIRGLDILSASPIDTEDQNLRKEKIEACRTISEQICAPSLRNTADFPRFLSIAISLLLRAHGDKDLNVYSVAEESLNRTIKILVYSYHERILFELFKVLKGKPHQHNNEKRLSTNLTDHLSQNSVTPSVPTTPNYQQSPSTQSPSHSTSNSSNNLYNNFSSNSNSNSNSNSNSSSNNNSGNTTPGNNTNNSNGNANSIFNTANQILSKPFPLKSQRIALIKFGEICSFIRPSKCRKYILSLVPPINSLLSIIEDESLQESISISMENISKILIPYLKENEVHQLIDLFSRNLQQPSAAVRRAASLSITSICRYHPRPL... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0017020",
"GO:0019208",
"GO:0019888",
"GO:0030234",
"GO:0098772"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0017020",
"GO:0019208",
"GO:0019888",
"GO:0030234",
"GO:0098772"
] | [] | null | 44689.Q76P24 | null | [
"IPR016024",
"IPR011989",
"IPR048413",
"IPR028426",
"IPR024613",
"IPR048411"
] | {"IPR011989": [193, 1085], "IPR016024": [196, 1289], "IPR028426": [433, 3091], "IPR048411": [215, 316], "IPR024613": [585, 1078], "IPR048413": [2582, 3030]} | - IPR016024: Armadillo-type fold (homologous_superfamily) [196-1289]
- IPR011989: Armadillo-like helical (homologous_superfamily) [193-1085]
- IPR048413: Huntingtin, C-terminal HEAT repeats (repeat) [2582-3030]
- IPR028426: Huntingtin family (family) [433-3091]
- IPR024613: Huntingtin, N-terminal, HEAT repeats 2 (repea... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring pho... | |
Q7Z4Q2 | HEAT repeat-containing protein 3 | Plays a role in ribosome biogenesis and in nuclear import of the 60S ribosomal protein L5/large ribosomal subunit protein uL18 (RPL5). Required for proper erythrocyte maturation | Homo sapiens (Human) | 680 | null | MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLGPLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDD... | [
"GO:0002262",
"GO:0002376",
"GO:0006606",
"GO:0006810",
"GO:0006886",
"GO:0006913",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0015031",
"GO:0021700",
"GO:0022613",
"GO:0030097",
"GO:0030099",
"GO:0030154",
"GO:0030218",
"GO:0032501",
"GO:0032502",
"GO:0033036",
"GO:0033365"... | [
"GO:0002262",
"GO:0002376",
"GO:0006606",
"GO:0006810",
"GO:0006886",
"GO:0006913",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0015031",
"GO:0021700",
"GO:0022613",
"GO:0030097",
"GO:0030099",
"GO:0030154",
"GO:0030218",
"GO:0032501",
"GO:0032502",
"GO:0033036",
"GO:0033365"... | [] | [] | AF-Q7Z4Q2-F1-model_v6.pdb | 9606.ENSP00000299192 | [
"Q9H3F4",
"Q9Y674",
"Q969E8",
"Q9BQ67",
"Q9H7B2"
] | [
"IPR016024",
"IPR011989",
"IPR052616",
"IPR057990"
] | {"IPR011989": [37, 679], "IPR016024": [37, 617], "IPR052616": [1, 676], "IPR057990": [417, 673]} | - Large ribosomal subunit protein uL18
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL5
- Glutamate-rich WD repeat-containing protein 1
- Ribosome production factor 2 homolog
- Pre-rRNA-processing protein TSR2 homolog | - IPR016024: Armadillo-type fold (homologous_superfamily) [37-617]
- IPR011989: Armadillo-like helical (homologous_superfamily) [37-679]
- IPR052616: SYO1-like (family) [1-676]
- IPR057990: SYO1-like, TPR repeats (domain) [417-673] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO... |
Q5ABE2 | Hypha-specific G1 cyclin-related protein 1 | Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis and opaque cells filamentous growth, and required for both conventional and pheromone-stimulated biofilm formation. Required to maintain hyphal tip localization of actin and SPA2. Regulates the CDC28 kinase during hyphal growth. The CDC28-... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 785 | null | MINITKPLTPKSISQQKQQQQHPYKNISTTKSNNNPQASGSKSFVQEKYPSQLYESEIKIHNQSLAEYDLDIYDIMVNLIETNKPNLSLYKQQPYLTFTIRLKLIDFLLKMSIRLKILPFVFFKAVKIFDRYCSKRIVLLDQSQLIITTCLWIASKVMGGNNHFVNINNLDKIGHENFRTINDLGYGCGGKYLGPTERFRLPKLHELVKLCGAKCKYDQGMFKQMEVHVLNTLEWSLNDPSIEEFIIDSHEFNVININNNNEYEQTITTNDESANANANDGNEFFKIKEFLSYAALYSHDLIDTNIIELGQVIMDLINET... | [
"GO:0002831",
"GO:0002833",
"GO:0008150",
"GO:0009268",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0030447",
"GO:0036176",
"GO:0036177",
"GO:0036178",
"GO:0036180",
"GO:0036244",
"GO:0040007",
"GO:0040008",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044111"... | [
"GO:0002831",
"GO:0002833",
"GO:0008150",
"GO:0009268",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0030447",
"GO:0036176",
"GO:0036177",
"GO:0036178",
"GO:0036180",
"GO:0036244",
"GO:0040007",
"GO:0040008",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044111"... | [
"GO:0003674",
"GO:0003824",
"GO:0004672",
"GO:0016301",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0140096"
] | [] | AF-Q5ABE2-F1-model_v6.pdb | 237561.Q5ABE2 | [
"Q5ALV2",
"Q5ALC8",
"Q5AB65",
"Q59WZ4",
"A0A1D8PCM9",
"A0A1D8PPK6",
"Q59XU5",
"A0A1D8PDA6",
"Q5AP97",
"Q59TL7",
"A0A1D8PED2",
"Q5ABG0",
"Q5ACY4",
"Q5AMQ3",
"Q59XB5",
"Q5AP71",
"Q59PG4",
"G1UB67",
"Q874L3",
"Q59TP1",
"Q59V96",
"Q5ALV8",
"Q59ME1",
"A0A1D8PH53",
"Q59LR2"... | [
"IPR013763",
"IPR006671",
"IPR048258",
"IPR036915"
] | {"IPR036915": [64, 238], "IPR006671": [71, 238], "IPR013763": [106, 231], "IPR048258": [101, 132]} | - Cyclin-dependent kinase 1
- Nucleoporin NSP1
- Transcriptional regulatory protein UME6
- Hyphal wall protein 1
- Extent of cell elongation protein 1
- G1/S-specific cyclin CLN3
- Transcription factor MBP1
- SCF ubiquitin ligase complex subunit
- Protein phosphatase PP2A regulatory subunit B
- Transcription factor MBP... | - IPR013763: Cyclin-like domain (domain) [106-231]
- IPR006671: Cyclin, N-terminal (domain) [71-238]
- IPR048258: Cyclins, cyclin-box (conserved_site) [101-132]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [64-238] | Molecular Function (MF): GO:0003674 (molecular function), GO:0016538 (cyclin-dependent protein serine/threonine kinase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0030447 (filamen... |
A0A1D8PCL1 | High-affinity glucose transporter 1 | High-affinity glucose transporter. Acts as a multifunctional complement-evasion molecule that causes down-regulation of complement activation by acquisition of human complement factors FH and C4BP. Also functions as a human immunodeficiency virus (HIV) receptor via binding the viral gp160 protein. Modulates hyphae form... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 545 | Cell membrane; Multi-pass membrane protein | MSSKIERIFSGPALKINTYLDKLPKIYNVFFIASISTIAGMMFGFDISSMSAFIGAEHYMRYFNSPGSDIQGFITSSMALGSFFGSIASSFVSEPFGRRLSLLTCAFFWMVGAAIQSSVQNRAQLIIGRIISGIGVGFGSAVAPVYGAELAPRKIRGLIGGMFQFFVTLGIMIMFYLSFGLGHINGVASFRIAWGLQIVPGLCLFLGCFFIPESPRWLAKQGQWEAAEEIVAKIQAHGDRENPDVLIEISEIKDQLLLEESSKQIGYATLFTKKYIQRTFTAIFAQIWQQLTGMNVMMYYIVYIFQMAGYSGNSNLVASS... | [
"GO:0002682",
"GO:0002683",
"GO:0002697",
"GO:0002698",
"GO:0002920",
"GO:0002921",
"GO:0006810",
"GO:0006950",
"GO:0008150",
"GO:0008643",
"GO:0008645",
"GO:0009266",
"GO:0009268",
"GO:0009408",
"GO:0009605",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0015749",
"GO:0030447"... | [
"GO:0002682",
"GO:0002683",
"GO:0002697",
"GO:0002698",
"GO:0002920",
"GO:0002921",
"GO:0006810",
"GO:0006950",
"GO:0008150",
"GO:0008643",
"GO:0008645",
"GO:0009266",
"GO:0009268",
"GO:0009408",
"GO:0009605",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0015749",
"GO:0030447"... | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005886",
"GO:0016020",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-A0A1D8PCL1-F1-model_v6.pdb | 237561.A0A1D8PCL1 | [
"Q59VZ0",
"A0A1D8PCN0"
] | [
"IPR036259",
"IPR050360",
"IPR005828",
"IPR020846",
"IPR005829",
"IPR003663"
] | {"IPR036259": [25, 498], "IPR003663": [25, 490], "IPR050360": [27, 523], "IPR005828": [34, 494], "IPR020846": [32, 483], "IPR005829": [89, 350]} | - Hgt2p
- Bifunctional protein GAL10 | - IPR036259: MFS transporter superfamily (homologous_superfamily) [25-498]
- IPR050360: Major Facilitator Superfamily Sugar Transporters (family) [27-523]
- IPR005828: Major facilitator, sugar transporter-like (family) [34-494]
- IPR020846: Major facilitator superfamily domain (domain) [32-483]
- IPR005829: Sugar trans... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0051119 (sugar transmembrane transporter activity), GO:0015145 (monosaccharide transmembrane transporter activity... |
P67697 | Antitoxin HicB | Antitoxin component of a type II toxin-antitoxin (TA) system. Functions as an mRNA interferase antitoxin; overexpression prevents HicA-mediated cessation of cell growth and inhibition of cell proliferation | Escherichia coli (strain K12) | 138 | null | MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALLTAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGKPKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802"
] | [] | AF-P67697-F1-model_v6.pdb | 511145.b1438 | [
"Q2MA50",
"Q2MAY7",
"P76371",
"Q2MBB8",
"Q47156",
"Q2M979",
"Q2M681",
"Q47149",
"Q2MA49",
"Q47157",
"P0C079",
"P0C077",
"Q47150",
"Q2M9C3",
"Q46865",
"Q46864",
"Q2M9C4",
"Q2M980",
"P23873",
"P77507",
"Q2M680"
] | [
"IPR051404",
"IPR010982",
"IPR001387",
"IPR035069",
"IPR031807"
] | {"IPR035069": [1, 64], "IPR010982": [82, 136], "IPR051404": [1, 73], "IPR031807": [3, 66], "IPR001387": [81, 136]} | - Probable mRNA interferase toxin HicA
- Antitoxin HigA
- mRNA interferase toxin HigB
- Antitoxin MazE
- mRNA interferase toxin RelE
- Antitoxin RelB
- Antitoxin MqsA
- Endoribonuclease toxin MazF
- Antitoxin ChpS
- Antitoxin DinJ | - IPR051404: Type II Toxin-Antitoxin System Antitoxin (family) [1-73]
- IPR010982: Lambda repressor-like, DNA-binding domain superfamily (homologous_superfamily) [82-136]
- IPR001387: Cro/C1-type, helix-turn-helix domain (domain) [81-136]
- IPR035069: Antitoxin HicB/UPF0150 (homologous_superfamily) [1-64]
- IPR031807: ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulatio... |
Q5ACW8 | Protein HIR1 | Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 907 | Nucleus | MQILKIPWFGHKTENKTVECYAVTINKDGTRLASGGLDGNVKIWDLTTINVFYKMADQPHKSKKDSTSTKLEESLPDKSLRRPLCSMSRHNGVVTSLKFSPDGRWLASGSDDKICLIWEKDNTQIAKSFGTDEHDLEHWTVRKRLVAHDNDIQDICWSPDGNLLVTVGLDRSVIIWNALTFEKIKRYDIHQSMVKGIVFDPANKFFATASDDRTVRIFRYYKKLNEYNNYEFQMEHVVVDPFKKSPLTSYFRRMSWSPDGQHIAVPNATNGPVPSVAIINRGNWGSDISLIGHEAPVEVCSFSPTLFQIADTPANEEIKF... | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003682",
"GO:0005488",
"GO:0031491",
"GO:0044877",
"GO:0000417",
"GO:0005575",
"GO:0032991"
] | [] | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003682",
"GO:0005488",
"GO:0031491",
"GO:0044877"
] | [
"GO:0000417",
"GO:0005575",
"GO:0032991"
] | AF-Q5ACW8-F1-model_v6.pdb | 237561.Q5ACW8 | [
"Q59MV1",
"Q5ADX2",
"A0A1D8PLL1",
"Q59RN6",
"Q5AGM0",
"Q5AKU2"
] | [
"IPR019015",
"IPR031120",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR055410",
"IPR019775",
"IPR011494"
] | {"IPR015943": [6, 438], "IPR036322": [20, 381], "IPR031120": [1, 848], "IPR055410": [84, 386], "IPR011494": [742, 849], "IPR019775": [32, 46], "IPR019015": [464, 485], "IPR001680": [1, 380]} | - Histone chaperone ASF1
- Protein HIR2
- Hpc2p
- Histone transcription regulator 3 homolog
- Histone H2A.Z-specific chaperone CHZ1
- Uncharacterized protein | - IPR019015: HIRA B motif (conserved_site) [464-485]
- IPR031120: WD repeat HIR1-like (family) [1-848]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [20-381]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [6-438]
- IPR001680: WD40 repeat (repe... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0044877 (protein-containing complex binding), GO:0003682 (chromatin binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003712 (transcript... |
Q5AGM0 | Protein HIR2 | Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,017 | Nucleus | MKFLKLPQSYHNGGIHSIDVNQDNTILVSGGTDNKIGVWNLKKLIELSKLVSTHNSPEVRLKLKSLEPKQYITCHKSLINVVRFFKGDNKRFISSDVNGNVFFHTLHEQPETKQLFPFKSIETSEVNPVVDLTISADNRLIAWSTNNGKVYLYDVVKDTFQELTSICHEKPIIQRSIAFDPSNNYLITVGDDTQINVFQYSYEKDDTSTTTYKFRLIYKISKLFSQNPLNVRYKRISWSPDGNLVSIPTASKNQTMLISLISRSEKWTNIESLVGHDFACDVVKFNPKIFSSKENDTSKVHSVIASGGSDRTMAIWNTSK... | [
"GO:0008150",
"GO:0010570",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033"
] | [
"GO:0008150",
"GO:0010570",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033"
] | [] | [] | AF-Q5AGM0-F1-model_v6.pdb | 237561.Q5AGM0 | [
"Q5AKU2",
"A0A1D8PDI5",
"Q5ACW8",
"Q59MV1",
"Q5ADX2"
] | [
"IPR019015",
"IPR031120",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR019775",
"IPR011494"
] | {"IPR015943": [2, 392], "IPR036322": [11, 371], "IPR031120": [1, 1015], "IPR011494": [717, 956], "IPR019775": [27, 41], "IPR019015": [529, 550], "IPR001680": [1, 360]} | - Histone transcription regulator 3 homolog
- Protein HIR1
- Histone chaperone ASF1
- Hpc2p
- Ubiquitin-binding protein | - IPR019015: HIRA B motif (conserved_site) [529-550]
- IPR031120: WD repeat HIR1-like (family) [1-1015]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [11-371]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [2-392]
- IPR001680: WD40 repeat (rep... | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003712 (transcription coregulator activity), GO:0003714 (transcription corepressor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:00508... |
Q5ADX2 | Histone transcription regulator 3 homolog | Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,591 | Nucleus | MSSFIPLNFLEDTVSKKDLEEEHTRELQVEQAYKLFQSALKLQKQKQYESAYKVYEELFKLDIVSNHYFEELDFIRGLQDGSQNTDTDELTLLSPNVKSLRYLIFRNRGFLYLDMLKSNTENKSAEKVKEMFYPLLDDFCIALLYNEPDEKLLETLHEIFSYIGSERLSRFVLEYSLTSRKESDDLSGLLPIDQTVLSQYKTMLEHLSSGKFPKLDLKHLSFLEPIRLDIFAQQEKLASKKVAVIKSTSTKWVDLLDAINIHLKENQDESKIEDANRPRIRIFEPYVLTEEPLDIVRIEFTKRGVAVPATETEVTKAQPE... | [
"GO:0008150",
"GO:0010570",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033"
] | [
"GO:0008150",
"GO:0010570",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033"
] | [] | [] | AF-Q5ADX2-F1-model_v6.pdb | 237561.Q5ADX2 | [
"Q5AKU2",
"Q5ACW8",
"Q5AGM0",
"Q59RN6",
"Q59MV1",
"A0A1D8PNS7"
] | [
"IPR033053"
] | {"IPR033053": [1, 1520]} | - Protein HIR2
- Protein HIR1
- Histone chaperone ASF1
- Cac2p
- Histone H2A.Z-specific chaperone CHZ1
- Hpc2p | - IPR033053: Histone transcription regulator 3/CABIN1 (family) [1-1520] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (ni... |
P06989 | Histidine biosynthesis bifunctional protein HisIE | null | Escherichia coli (strain K12) | 203 | Cytoplasm | MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTLESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQGLDLTTVIENLRKRHQ | [
"GO:0003674",
"GO:0003824",
"GO:0004636",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004636",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818"
] | [] | AF-P06989-F1-model_v6.pdb | 511145.b2026 | [
"P06986",
"Q2MAH1",
"P78078",
"Q2MAH3",
"P78077",
"Q2M6B2",
"P60664",
null,
"Q2MCC5",
"Q47669",
"Q6LEL0",
"P94704",
"Q47254",
"P60595",
"P78302",
"Q2M900",
"Q2M5S9",
"P77650",
"Q2M8N6",
"Q2MAH0",
"P60757",
"P29015",
"P0AE18",
"Q2M8N2",
"Q47060",
"Q2M6U1",
"P78146"... | [
"IPR021130",
"IPR002496",
"IPR023019",
"IPR008179",
"IPR038019"
] | {"IPR038019": [2, 122], "IPR023019": [8, 203], "IPR008179": [112, 198], "IPR021130": [115, 202], "IPR002496": [33, 105]} | - Histidinol-phosphate aminotransferase
- 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
- Histidine biosynthesis bifunctional protein HisB
- Imidazole glycerol phosphate synthase subunit HisF
- Histidinol dehydrogenase
- Imidazole glycerol phosphate synthase subunit ... | - IPR021130: Phosphoribosyl-ATP pyrophosphohydrolase-like (family) [115-202]
- IPR002496: Phosphoribosyl-AMP cyclohydrolase domain (domain) [33-105]
- IPR023019: Histidine biosynthesis bifunctional protein HisIE (family) [8-203]
- IPR008179: Phosphoribosyl-ATP pyrophosphohydrolase (family) [112-198]
- IPR038019: Phosph... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), ... |
P76341 | 5-hydroxyisourate hydrolase | Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) | Escherichia coli (strain K12) | 137 | Periplasm | MLKRYLVLSVATAAFSLPSLVNAAQQNILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [] | [] | AF-P76341-F1-model_v6.pdb | 511145.b1970 | [
"P97172",
"Q2MAZ7",
"Q46816",
"Q2MAZ6"
] | [
"IPR036817",
"IPR014306",
"IPR023419",
"IPR023418",
"IPR000895",
"IPR023416"
] | {"IPR036817": [24, 137], "IPR014306": [27, 137], "IPR000895": [28, 137], "IPR023416": [23, 137], "IPR023419": [120, 132], "IPR023418": [32, 47]} | - Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ
- Protein-methionine-sulfoxide reductase catalytic subunit MsrP
- Transcriptional regulatory protein HprR
- Guanine deaminase | - IPR036817: Transthyretin/hydroxyisourate hydrolase domain superfamily (homologous_superfamily) [24-137]
- IPR014306: Hydroxyisourate hydrolase (family) [27-137]
- IPR023419: Transthyretin, conserved site (conserved_site) [120-132]
- IPR023418: Transthyretin, thyroxine binding site (binding_site) [32-47]
- IPR000895: ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016812 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides)
Biological ... |
Q2FVK1 | Gamma-hemolysin component B | Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. Promotes host AMFR-mediated inflammation by mediating 'Lys-27'-linked ubiquitination of TAB3, TAK1-TAB3 complex formation and phosphorylation of TAK1/MAP3K7. In turn, activates host NF-kappa-B signaling path... | Staphylococcus aureus (strain NCTC 8325 / PS 47) | 325 | Secreted | MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKE... | [
"GO:0000209",
"GO:0007154",
"GO:0007165",
"GO:0007249",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0016567",
"GO:0019538",
"GO:0023052",
"GO:0032446",
"GO:0035556",
"GO:0035821",
"GO:0036211",
"GO:0038061",
"GO:0043170",
"GO:0043412",
"GO:0043687",
"GO:0044003",
"GO:0044068"... | [
"GO:0000209",
"GO:0007154",
"GO:0007165",
"GO:0007249",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0016567",
"GO:0019538",
"GO:0023052",
"GO:0032446",
"GO:0035556",
"GO:0035821",
"GO:0036211",
"GO:0038061",
"GO:0043170",
"GO:0043412",
"GO:0043687",
"GO:0044003",
"GO:0044068"... | [
"GO:0003674",
"GO:0060090"
] | [
"GO:0005575",
"GO:0018995",
"GO:0030430",
"GO:0033643",
"GO:0033646",
"GO:0033647",
"GO:0033648",
"GO:0033655",
"GO:0043656",
"GO:0044165",
"GO:0044217",
"GO:0110165"
] | AF-Q2FVK1-F1-model_v6.pdb | 93061.SAOUHSC_02710 | [
"Q2FVK2",
"Q2FVK3"
] | [
"IPR036435",
"IPR016183",
"IPR003963"
] | {"IPR036435": [28, 324], "IPR003963": [5, 315], "IPR016183": [60, 310]} | - Gamma-hemolysin component C
- Gamma-hemolysin h-gamma-ii subunit, putative | - IPR036435: Leukocidin/porin MspA superfamily (homologous_superfamily) [28-324]
- IPR016183: Leukocidin/Hemolysin toxin (domain) [60-310]
- IPR003963: Bi-component toxin, staphylococci (family) [5-315] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0001906 (cell killing), GO:0031... |
P12684 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 | HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway constitutes by the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA). HMG1 and HMG2 catalyze the reduction of hydroxymethylglutaryl-CoA (HMG-CoA)... | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | 1,045 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope | MSLPLKTIVHLVKPFACTARFSARYPIHVIVVAVLLSAAAYLSVTQSYLNEWKLDSNQYSTYLSIKPDELFEKCTHYYRSPVSDTWKLLSSKEAADIYTPFHYYLSTISFQSKDNSTTLPSLDDVIYSVDHTRYLLSEEPKIPTELVSENGTKWRLRNNSNFILDLHNIYRNMVKQFSNKTSEFDQFDLFIILAAYLTLFYTLCCLFNDMRKIGSKFWLSFSALSNSACALYLSLYTTHSLLKKPASLLSLVIGLPFIVVIIGFKHKVRLAAFSLQKFHRISIDKKITVSNIIYEAMFQEGAYLIRDYLFYISSFIGCAI... | [
"GO:0006066",
"GO:0006629",
"GO:0006694",
"GO:0006696",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008204",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016125",
"GO:0016126",
"GO:0016129",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046165",
"GO:1902652",
"GO:1902653"... | [
"GO:0006066",
"GO:0006629",
"GO:0006694",
"GO:0006696",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008204",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016125",
"GO:0016126",
"GO:0016129",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046165",
"GO:1902652",
"GO:1902653"... | [] | [] | AF-P12684-F1-model_v6.pdb | 4932.YLR450W | [
"Q08109",
"Q6B1C8",
"P15495",
"P24521",
"Q45U36",
"P25694",
"Q05787",
"P41338",
"P10614",
"P32476",
"P07277",
"P12683",
"P29704",
"P54839",
"Q02159",
"Q04228",
"Q6Q5G1",
"Q45U26",
"P15496"
] | [
"IPR023076",
"IPR025583",
"IPR023282",
"IPR009029",
"IPR009023",
"IPR023074",
"IPR000731",
"IPR053958",
"IPR004554",
"IPR002202"
] | {"IPR009029": [598, 1011], "IPR023282": [601, 687], "IPR023074": [688, 1016], "IPR009023": [738, 856], "IPR002202": [211, 1024], "IPR004554": [612, 1021], "IPR025583": [10, 159], "IPR000731": [188, 356], "IPR053958": [213, 361], "IPR023076": [797, 1019]} | - 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
- Hydroxymethylglutaryl-CoA synthase
- Mevalonate kinase
- ERAD-associated E3 ubiquitin-protein ligase HRD1
- Protein NSG1
- Squalene epoxidase ERG1
- Squalene synthase ERG9
- Isopentenyl-diphosphate delta-isomerase
- Farnesyl pyrophosphate synthase
- Cell division co... | - IPR023076: Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site (conserved_site) [797-1019]
- IPR025583: HMG-CoA reductase, N-terminal domain (domain) [10-159]
- IPR023282: Hydroxymethylglutaryl-CoA reductase, N-terminal (homologous_superfamily) [601-687]
- IPR009029: Hydroxymethylglutaryl-CoA reductase, c... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of do... |
Q9NZL4 | Hsp70-binding protein 1 | Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR | Homo sapiens (Human) | 359 | null | MSDEGSRGSRLPLALPPASQGCSSGGGGGGSSAGGSGNSRPPRNLQGLLQMAITAGSEEPDPPPEPMSEERRQWLQEAMSAAFRGQREEVEQMKSCLRVLSQPMPPTAGEAEQAADQQEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVRTEHSPFHEHVLGALCSLVTDFPQGVRECREPELGLEEL... | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | AF-Q9NZL4-F1-model_v6.pdb | 9606.ENSP00000255631 | [
"Q9UK02",
"Q58J86",
"Q6IRY4",
"Q02543",
"Q9UPC4",
"Q5R358",
"Q9H9S3",
"Q9Y2R9",
"Q9HB96",
"Q9H2K1",
"P62273",
"Q16699",
"Q5TZU9",
"Q8TCW5",
"P22090",
"P61011",
"Q6IRY0",
"Q9UN54",
"Q9P0M9",
"Q9BVN7",
"Q96Q52",
"Q9NVR3",
"Q9BWQ0",
"Q9UMN7",
"Q8IWA2",
"Q9BYD2",
"Q5I... | [
"IPR016024",
"IPR011989",
"IPR013918",
"IPR050693"
] | {"IPR011989": [84, 359], "IPR016024": [91, 350], "IPR050693": [40, 348], "IPR013918": [45, 139]} | - Heat shock cognate 71 kDa protein
- Heat shock 70 kDa protein 4
- Heat shock 70 kDa protein 1A
- Heat shock 70 kDa protein 1B
- Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- BAG family molecular chaperone regulator 1
- Heat shock protein 105 kDa
- E3 ubiquitin-protein ligase CHIP
- BAG family molecular ... | - IPR016024: Armadillo-type fold (homologous_superfamily) [91-350]
- IPR011989: Armadillo-like helical (homologous_superfamily) [84-359]
- IPR013918: Nucleotide exchange factor Fes1 (domain) [45-139]
- IPR050693: Hsp70 Nucleotide Exchange Factors and Inhibitors (family) [40-348] | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0019899 (enzyme binding), GO:0004857 (enzyme inhibitor activity... |
Q5AQ33 | Heat shock transcription factor | DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription. With HSP90, is required for the modulation of the chaperone levels in response to growth temperature, rather than the activation of acute responses to sudden thermal transitions. Activated during inf... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 760 | Nucleus | MIMNMTTDYRDPLLDLFGTESNSGNETSSPSDIPVINRSGTFNQQQFSPLLTQQSLYNTPNSGSTPNIFDPNYTQMQEEQTSPSSNKLQPEDPPRKKRNTRSQTKIHQQSEGDEYNSNDYKDSIDLDKPPVVEPSPPFFVESDTTPEFVIPTPTSEQQQQQHHELIAQDYQRSNNSNQFGNLTHYEPNLPPLPPLSESILPQTNTFHPLVLPHDPRHAITAGPANNSQQQQQQQQQDSSIPSDGISSKIQQLHAPSLSNNQSASQRKKKESSGPKTRPAFVMKIWSMVNDPANHEYIRWNDDGKTFQVFHREDFMKVILP... | [
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009266",
"GO:0009408",
"GO:0009628",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0033554",
"GO:0034605",
"GO:0045893"... | [
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009266",
"GO:0009408",
"GO:0009628",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0033554",
"GO:0034605",
"GO:0045893"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5AQ33-F1-model_v6.pdb | 237561.Q5AQ33 | [
"A0A1D8PG96",
"O74261",
"A0A1D8PG03",
"Q5A4X5",
"Q5AKZ7",
"Q5A678",
"A0A1D8PQ94",
"Q59VM8",
"A0A1D8PHK4",
"Q5AI38",
"A0A1D8PTP9",
"Q5AH23",
"Q59V92",
"Q92207",
"Q5A397"
] | [
"IPR036390",
"IPR000232",
"IPR036388"
] | {"IPR036388": [273, 386], "IPR036390": [277, 384], "IPR000232": [276, 385]} | - Hsp90 cochaperone
- Heat shock protein 90 homolog
- Heat shock protein HSP70
- Chaperone ATPase
- Heat shock protein SSA2
- Flavin reductase like domain-containing protein
- Uncharacterized protein
- Mitogen-activated protein kinase HOG1
- Type II HSP40 co-chaperone
- Ssz1p | - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [277-384]
- IPR000232: Heat shock factor (HSF)-type, DNA-binding (domain) [276-385]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [273-386] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biologica... |
Q5AG71 | Serine/threonine-protein kinase HSL1 | Protein kinase involved in determination of morphology during the cell cycle of both yeast-form and hyphal cells via regulation of SWE1 and CDC28. Regulates pseudohypha formation, but is not required for septin ring organization or septum formation. Plays an essential role in virulence in a mouse model | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,462 | Bud neck. Note=In the hyphal cells, localizes at a potent septation site before the completion of septum formation | MSTVVNRRSSHQFDSPSNHLDHSSSMNVDKVVQSVTNATKRLSQISTNTNNSNKKRKTQNKIGPWKLGRTLGRGSTGRVRLAKNTTTGQLAAVKIVPKSNFKKLENPKYKRSKEDATRLPYGIEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEYEAINYFKQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKEKLLETSCGSPHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQSGKFNMPPELSFEAKDLITKMLKVNPRERIT... | [
"GO:0001403",
"GO:0001558",
"GO:0006950",
"GO:0007124",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010570",
"GO:0016049",
"GO:0030308",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0040008",
"GO:0042149",
"GO:0042594",
"GO:0044182"... | [
"GO:0001403",
"GO:0001558",
"GO:0006950",
"GO:0007124",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010570",
"GO:0016049",
"GO:0030308",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0040008",
"GO:0042149",
"GO:0042594",
"GO:0044182"... | [
"GO:0003674",
"GO:0003824",
"GO:0004672",
"GO:0016301",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005856",
"GO:0005933",
"GO:0005935",
"GO:0005938",
"GO:0005940",
"GO:0030427",
"GO:0032156",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0071944",
"GO:0110165"
] | AF-Q5AG71-F1-model_v6.pdb | 237561.Q5AG71 | [
"A0A1D8PJ05",
"Q92207",
"Q5ACY4",
"Q59W62",
"A0A1D8PCY5",
"Q5AP97",
"Q5A326",
"A0A1D8PE86"
] | [
"IPR008271",
"IPR011009",
"IPR017441",
"IPR000719",
"IPR031850"
] | {"IPR011009": [62, 331], "IPR000719": [65, 330], "IPR031850": [1326, 1455], "IPR008271": [197, 209], "IPR017441": [71, 94]} | - Mitosis inhibitor protein kinase SWE1
- Mitogen-activated protein kinase HOG1
- Cdh1p
- M-phase inducer phosphatase
- Anaphase promoting complex subunit
- Serine/threonine-protein kinase GIN4
- Anaphase promoting complex subunit
- Septin | - IPR008271: Serine/threonine-protein kinase, active site (active_site) [197-209]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [62-331]
- IPR017441: Protein kinase, ATP binding site (binding_site) [71-94]
- IPR000719: Protein kinase domain (domain) [65-330]
- IPR031850: Fungal kinase ass... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring pho... |
Q5AQ47 | NAD-dependent protein deacetylase HST1 | NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 655 | Nucleus | MPGDNDIVLVDSSSDNEEEREEDDDDESQHREIKKFKPNPNPSQTRDMNESHVINKSNFSTVPFNAVSSSSSSDNDQDNDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEESEINGNQISLSIDDEYDSEGLTKESSRTPIGSNTSDIIINGVTIITNNNDSSLVASSSDDDDDDDDDDDKDDDNDDDASDLESDFAFEEIPPSLIMETRKYLKQNGTMKFLEKYLPTAASIENIIKLILQLGFVPKRKLNNGLDENDIMEYIKILNHAIIKVKSIRERREDITTINDALKLIENSKNIMVITGAGISTSLGIPDFR... | [
"GO:0008150",
"GO:0009987",
"GO:0036166",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0036166"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5AQ47-F1-model_v6.pdb | 237561.Q5AQ47 | [
"Q5ABG1",
"A0A1D8PI52",
"Q5ANB6",
"A0A1D8PI06",
"A0A1D8PPW7",
"A0A1D8PKE0",
"A0A1D8PLH8",
"Q5A309",
"A0A1D8PRN2",
"Q5ADP0",
"Q5AL24",
"Q5ALW6",
"A0A1D8PMG7",
"A0A1D8PRE2",
"A0A1D8PFD3",
"A0A1D8PJ17",
"A0A1D8PJL8"
] | [
"IPR026591",
"IPR029035",
"IPR007654",
"IPR003000",
"IPR026590",
"IPR050134"
] | {"IPR029035": [270, 586], "IPR026591": [313, 506], "IPR050134": [283, 587], "IPR003000": [307, 534], "IPR007654": [197, 251], "IPR026590": [282, 583]} | - nicotinamidase
- Nicotinamide-nucleotide adenylyltransferase
- Glutamine-dependent NAD(+) synthetase
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- NADH/NAD(+) kinase
- Purine nucleoside phosphorylase
- NAD(+) diphosphatase
- Nicotinamide-nucleotide adenylyltr... | - IPR026591: Sirtuin, catalytic core small domain superfamily (homologous_superfamily) [313-506]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [270-586]
- IPR007654: NAD-dependent histone deacetylase Sir2, N-terminal (domain) [197-251]
- IPR003000: Sirtuin family (family) [307-534]
-... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0033558 (protein lysine deacetylase activity), GO:00192... |
Q5A985 | NAD-dependent protein deacetylase HST2 | NAD-dependent histone deacetylase that is involved in nuclear silencing events. Derepresses subtelomeric silencing and increases repression in nucleolar (rDNA) silencing. Its function is negatively regulated by active nuclear export (By similarity) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 331 | Cytoplasm. Nucleus | MPSLDDILKPVAEAVKNGKKVTFFNGAGISTGAGIPDFRSPDTGLYANLAKLNLPFAEAVFDIDFFKEDPKPFYTLAEELYPGNFAPTKFHHFIKLLQDQGSLKRVYTQNIDTLERLAGVEDKYIVEAHGSFASNHCVDCHKEMTTETLKTYMKDKKIPSCQHCEGYVKPDIVFFGEGLPVKFFDLWEDDCEDVEVAIVAGTSLTVFPFASLPGEVNKKCLRVLVNKEKVGTFKHEPRKSDIIALHDCDIVAEKLCTLLGLDDKLNEVYEKEKIKYSKAETKETKMHEIEDKLKEEAHLKEDKHTTKVDKKEKQNDANDK... | [
"GO:0008150",
"GO:0009987",
"GO:0036166",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0036166"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | AF-Q5A985-F1-model_v6.pdb | 237561.Q5A985 | [
"Q5ALW6",
"A0A1D8PRE2",
"A0A1D8PMG7",
"A0A1D8PJL8",
"A0A1D8PJ17",
"A0A1D8PSA6",
"Q5A309",
"A0A1D8PRN2",
"A0A1D8PLH8",
"Q5ADP0",
"Q5ACY2",
"Q5AL24",
"A0A1D8PI06",
"Q5ANB6",
"A0A1D8PPW7",
"A0A1D8PKE0",
"Q59VN4",
"A0A1D8PLA7"
] | [
"IPR026591",
"IPR029035",
"IPR003000",
"IPR026590",
"IPR050134",
"IPR017328"
] | {"IPR029035": [4, 277], "IPR026591": [32, 180], "IPR017328": [7, 321], "IPR050134": [8, 270], "IPR003000": [26, 208], "IPR026590": [1, 262]} | - Glutamine-dependent NAD(+) synthetase
- Nicotinamide-nucleotide adenylyltransferase
- nicotinamidase
- NADH/NAD(+) kinase
- NAD(+) diphosphatase
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- Purine nucleoside phosphorylase
- Nicotinamide-nucleotide adenylyltr... | - IPR026591: Sirtuin, catalytic core small domain superfamily (homologous_superfamily) [32-180]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [4-277]
- IPR003000: Sirtuin family (family) [26-208]
- IPR026590: Sirtuin family, catalytic core domain (domain) [1-262]
- IPR050134: NAD-dep... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0033558 (protein lysine deacetylase activity), GO:00192... |
Q5A1W9 | NAD-dependent histone deacetylase HST3 | NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 487 | Cytoplasm. Nucleus | MISIDLLDNSGTSMPADTSIKLHEVIKFISKSKKMTVLTGAGISCNAGIPDFRSSDGLYNMVKAKHPKAVVRGQDLFDISLFRDEMSLSVFCTFMESLYKSSLNAKPTETHKFIKILKDKNKLLRCYTQNIDCIEQHINLKLGINLQEFDNNKFKQVWNQLDVVQLHGNLHKLSCTNCFSQFNWNEEFQTLLANGLNPECSKCMDKYQQRLYSGKRLTGQTIGLLRPDIVLYGEHHPQMEILTQGLNSDLKSRPDCLIIMGTSLKVAGVKSLVKSLSKIIHNKGGKVIYVNKTKLSASSWKNYIDYEVVSDCDEFVRMLK... | [
"GO:0008150",
"GO:0009987",
"GO:0010570",
"GO:0030447",
"GO:0036166",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045926",
"GO:0048519",
"GO:0050789",
"GO:0050794",
"GO:0060258",
"GO:0065007",
"GO:1900239",
"GO:1900428",
"GO:1900429",
"GO:0003674",
"GO:0003824",
"GO:0004407"... | [
"GO:0008150",
"GO:0009987",
"GO:0010570",
"GO:0030447",
"GO:0036166",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045926",
"GO:0048519",
"GO:0050789",
"GO:0050794",
"GO:0060258",
"GO:0065007",
"GO:1900239",
"GO:1900428",
"GO:1900429"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004407",
"GO:0019213",
"GO:0033558",
"GO:0140096",
"GO:0140993",
"GO:0160215"
] | [] | AF-Q5A1W9-F1-model_v6.pdb | 237561.Q5A1W9 | [
"Q5AAJ8",
"A0A1D8PKE0",
"A0A1D8PPW7",
"A0A1D8PI06",
"Q5AL24",
"Q59VF4",
"Q59VN2",
"A0A1D8PRN2",
"A0A1D8PJL8",
"A0A1D8PRE2",
"Q5ADQ0",
"Q5ALW6"
] | [
"IPR026591",
"IPR029035",
"IPR003000",
"IPR026590",
"IPR050134"
] | {"IPR029035": [13, 335], "IPR026591": [46, 237], "IPR050134": [21, 330], "IPR003000": [40, 267], "IPR026590": [15, 336]} | - Nicotinamide-nucleotide adenylyltransferase
- nicotinamidase
- Glutamine-dependent NAD(+) synthetase
- NADH/NAD(+) kinase
- Histone acetyltransferase RTT109
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- Purine nucleoside phosphorylase
- NAD(+) diphosphatase
-... | - IPR026591: Sirtuin, catalytic core small domain superfamily (homologous_superfamily) [46-237]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [13-335]
- IPR003000: Sirtuin family (family) [40-267]
- IPR026590: Sirtuin family, catalytic core domain (domain) [15-336]
- IPR050134: NAD-d... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0033558 (protein lysine deacetylase activity), GO:00192... |
A0A0R4IBL7 | Transcription factor 12 | Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis | Danio rerio (Zebrafish) (Brachydanio rerio) | 726 | Nucleus | MNPQQRIAAIGTDKELSDLLDFSAMFSPPVNSGKNRPTTLGSSQFTASGMDERTSQASWASGGQSSPSFESSRGFADSHYADHLSDSRLVSHEGLSPTPFMSSSIMGKSERPPFSGYGREPGVSGCQSNLRSDIQLASPGPVTTPGKSPTPFYSYTGPNPRRRPLQDSASMDPLQTKKVRKPPPGLPTSVYAPSPSSEDFNRDSPSYPSPKPPGSMFASTFFDGTHNSSDQWNLSNGISQPGYGGMLGGSSSHMPQSGNYSNLHSHDRLNYPPHSVSPTDINASLPPMSSFHRSSASTSPFVTASHTPPVNTTEGVMAAA... | [
"GO:0007275",
"GO:0007399",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022008",
"GO:0030030",
"GO:0030154",
"GO:0030182",
"GO:0031175",
"GO:0032501",
"GO:0032502",
"GO:0048468",
"GO:0048666",
"GO:0048699",
"GO:0048731",
"GO:0048856",
"GO:0048869",
"GO:0071840",
"GO:0120036"... | [
"GO:0007275",
"GO:0007399",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022008",
"GO:0030030",
"GO:0030154",
"GO:0030182",
"GO:0031175",
"GO:0032501",
"GO:0032502",
"GO:0048468",
"GO:0048666",
"GO:0048699",
"GO:0048731",
"GO:0048856",
"GO:0048869",
"GO:0071840",
"GO:0120036"... | [] | [] | AF-A0A0R4IBL7-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR011598",
"IPR051098"
] | {"IPR036638": [607, 688], "IPR051098": [5, 725], "IPR011598": [621, 680]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [607-688]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [621-680]
- IPR051098: Neuronal Differentiation E-box Binding Transcription Factors (family) [5-725] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biologica... | |
Q6DHQ1 | Voltage-gated hydrogen channel 1 | Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity) | Danio rerio (Zebrafish) (Brachydanio rerio) | 235 | Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein | MSRYLKHFTAVGDNKSAVPTWHEEDTSHHVTTLHDAPDGLEVSTGQHLGQLSFRDSLRKLYSTERFQIVVVCLVVLDAIFVLCELLIDLSIIEADHHRIAPQVFHYLSLALLTFFMVELAGKIFAYRLEFLHHKFEVFDGIVVVVSFILDIIYISKEDAFDAMGLLILLRLWRVARIINGILVSVQNRANHRVEKLKEINESLVHQVNELKEQNTKMDQENVRLRALLKDHSIDF | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q6DHQ1-F1-model_v6.pdb | 7955.ENSDARP00000059027 | [
"E7F8M2",
"X1WEI7",
"F1QG29"
] | [
"IPR005821",
"IPR031846",
"IPR027359"
] | {"IPR027359": [56, 183], "IPR031846": [1, 234], "IPR005821": [66, 181]} | - Transmembrane phosphatase with tensin homology
- Potassium voltage-gated channel subfamily A member 2 | - IPR005821: Ion transport domain (domain) [66-181]
- IPR031846: Voltage-gated hydrogen channel 1 (family) [1-234]
- IPR027359: Voltage-dependent channel domain superfamily (homologous_superfamily) [56-183] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0043167 (ion binding), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0043169 (cation binding), GO:0022803 (passive transmembrane tra... |
P46593 | Hyphal wall protein 1 | Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within p... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 634 | Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Hyphal surface. Localizes to the a/a Portion of the conjugation bridge during mating | MRLSTAQLIAIAYYMLSIGATVPQVDGQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPATTTTSESSSSSSSSSSSTTPKTSASTTPESSVPATTPNTSVPTTSSESTTPATSPESSVPVTSGSSILATTSESSSAPATTPNTSVPTTTTEAKSSSTPLTTTTEHDTTVVTVTSCS... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0050839",
"GO:0005575",
"GO:0005618",
"GO:0005937",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030446",
"GO:0042995",
"GO:0071944",
"GO:0110165",
"GO:0120025"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0050839"
] | [
"GO:0005575",
"GO:0005618",
"GO:0005937",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030446",
"GO:0042995",
"GO:0071944",
"GO:0110165",
"GO:0120025"
] | AF-P46593-F1-model_v6.pdb | 237561.P46593 | [
"Q5A8N2",
"Q5ANJ4",
"Q5A0E5",
"Q59ME1",
"Q5A8T4",
"Q5A661",
"Q5ACU9",
"Q5ACC9",
"Q59LY1",
"Q5ALC8",
"Q5AB65",
"Q9UW14",
"Q59WZ4",
"Q59XU5",
"Q5AH23",
"Q5ABE2",
"A0A1D8PFP2",
"G1UB67",
"Q874L3",
"Q59U34",
"Q59TP1",
"Q59XB5",
"Q5A8I8",
"Q5ABW5",
"Q59PG4"
] | [
"IPR025928"
] | {"IPR025928": [311, 415]} | - Agglutinin-like protein 3
- Extent of cell elongation protein 1
- Hyphally regulated cell wall protein 1
- Transcriptional regulatory protein UME6
- Transcriptional regulator NRG1
- Agglutinin-like protein 1
- Hypha-specific G1 cyclin-related protein 1
- Secreted aspartic protease 5
- Enhanced filamentous growth prot... | - IPR025928: Flocculin type 3 repeat (repeat) [311-415] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051... |
Q59PF9 | Hyphal wall protein 2 | GPI-anchored cell wall protein required for mating efficiency, biofilm formation, adhesion, filamentous growth, and oxidative stress tolerance. Involved in normal disseminated infection in a mouse systemic candidiasis model | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 908 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=localizes to the cell wall of hyphae | MRFATTQLATLACFILTAEATFPLRGLFNDAPVDVDLGVYHEESGNNKEQKVDGFNMSPNIKKRTNENNAANVVSTNGGLFITSTKELKTTVVVTSCFNNVCSETSITTPKTAVTATTSKHSTSKPTYTTTSKHSTSHSSTPASTSKHSTSTSTHPATSEHSTSKSTHATSSKHSTSKSSVSVTTSKHSTHDTTSKSFVTPPASSTTSEHTKHKSHKPSKTVVTLTSCSNNACSQSEITTGAIVVTDKETVYTTYCPLTDTETETESTTATTSKHSTHTTTSKHSSVESTSVTSSSKHSVSKSTDVTTSKHSSSESSHAT... | [
"GO:0008150",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743",
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312"... | [
"GO:0008150",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0030446",
"GO:0071944",
"GO:0110165"
] | AF-Q59PF9-F1-model_v6.pdb | 237561.Q59PF9 | [
"Q5ALC8",
"Q874L3"
] | [
"IPR025928"
] | {"IPR025928": [221, 748]} | - Agglutinin-like protein 3
- Hyphally regulated cell wall protein 1 | - IPR025928: Flocculin type 3 repeat (repeat) [221-748] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0044010 (sin... |
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