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patient_id
string
sku
string
age_at_baseline
float64
sex
string
race_ethnicity
string
insurance_type
string
ses_index
float64
food_insecurity_flag
int64
urban_flag
int64
mets_cluster
int64
mets_cluster_label
string
mets_idf_flag
int64
mets_ncep_flag
int64
mets_z_score
float64
mets_component_count
int64
mets_duration_years
float64
bmi_kg_m2
float64
weight_kg
float64
height_cm
float64
waist_circumference_cm
float64
waist_hip_ratio
float64
body_fat_pct
float64
visceral_fat_area_cm2
float64
subcutaneous_fat_area_cm2
float64
visceral_adiposity_index
float64
lip_accum_product
float64
waist_criterion
int64
total_cholesterol_mgdl
float64
ldl_mgdl
float64
hdl_mgdl
float64
triglycerides_mgdl
float64
vldl_mgdl
float64
non_hdl_mgdl
float64
apob_mg_dl
float64
lipoprotein_a_nmol_l
float64
sdldl_mgdl
float64
tg_hdl_ratio
float64
remnant_cholesterol_mgdl
float64
tg_criterion
int64
hdl_criterion
int64
statin_flag
int64
statin_type
string
statin_ldl_reduction_pct
int64
fibrate_flag
int64
fibrate_tg_reduction_pct
float64
fibrate_hdl_increase_pct
float64
omega3_supplement_flag
int64
fasting_glucose_mgdl
float64
hba1c_pct
float64
fasting_insulin_uIU_ml
float64
homa_ir
float64
homa_b
float64
ogtt_2hr_glucose_mgdl
float64
t2dm_flag
int64
prediabetes_flag
int64
fg_criterion
int64
metformin_flag
int64
glp1_agonist_flag
int64
sglt2_inhibitor_flag
int64
insulin_flag
int64
glp1_mace_relative_risk
float64
sglt2_hf_relative_risk
float64
sbp_mmhg
float64
dbp_mmhg
float64
sbp_treated_mmhg
float64
dbp_treated_mmhg
float64
pulse_pressure_mmhg
float64
map_mmhg
float64
hypertension_flag
int64
sbp_criterion
int64
bp_criterion
int64
bp_medication_class
string
bp_control_flag
int64
abpm_flag
int64
nocturnal_dip_flag
int64
ascvd_10yr_risk_pct
float64
score2_10yr_risk_pct
float64
framingham_risk_score
float64
cvd_risk_category
string
mace_flag
int64
mace_years_to_event
float64
coronary_artery_disease_flag
int64
stroke_flag
int64
heart_failure_flag
int64
atrial_fibrillation_flag
int64
peripheral_artery_disease_flag
int64
carotid_imt_mm
float64
coronary_calcium_score
int64
hs_crp_mg_l
float64
nt_probnp_pg_ml
float64
troponin_i_ng_ml
float64
adiponectin_ug_ml
float64
leptin_ng_ml
float64
leptin_resistance_flag
int64
il6_pg_ml
float64
tnf_alpha_pg_ml
float64
resistin_ng_ml
float64
visfatin_ng_ml
float64
omentin1_ng_ml
float64
egfr_ml_min_173m2
float64
uacr_mg_g
float64
ckd_flag
int64
alt_u_l
float64
ast_u_l
float64
ggt_u_l
float64
liver_fibrosis_fib4
float64
nafld_flag
int64
nash_flag
int64
uric_acid_mgdl
float64
hyperuricemia_flag
int64
hypothyroidism_flag
int64
tsh_uIU_ml
float64
cortisol_am_ug_dl
float64
osa_flag
int64
ahi_events_per_hour
float64
depression_flag
int64
phq9_score
int64
anxiety_flag
int64
stress_pss_score
int64
smoking_status
string
alcohol_drinks_per_week
int64
diet_pattern
string
diet_quality_score
float64
physical_activity_level
string
exercise_min_per_week
float64
vo2max_ml_kg_min
float64
sedentary_hours_per_day
float64
steps_per_day
int64
sleep_hours_per_night
float64
intervention_type
string
lifestyle_arm
string
dietary_adherence_pct
float64
caloric_deficit_kcal_day
int64
weight_loss_achieved_1yr_pct
float64
metformin_intervention_flag
int64
intervention_adherence_pct
float64
mets_resolution_1yr_flag
int64
mets_resolution_3yr_flag
int64
mets_resolution_5yr_flag
int64
pcp_visits_per_year
int64
cardiology_referral_flag
int64
endocrinology_referral_flag
int64
dietitian_referral_flag
int64
hospitalization_flag
int64
total_healthcare_cost_usd
int64
medication_adherence_pct
float64
quality_of_life_eq5d
float64
icd10_primary
string
loinc_glucose
string
loinc_hba1c
string
loinc_sbp
string
HC005-00000001
HC-END-005
55.7
Male
Black
Medicare
1.3
1
1
0
Metabolically_Healthy
0
0
0.188
1
0
30.8
92.6
173.5
98.6
1.04
33.5
50
384.1
6.48
63.5
0
130
51.2
42.7
119.6
23.9
87.3
50
25.8
10
2.8
54.4
0
0
1
Atorvastatin
60
0
0
0
0
93.9
6.7
29.3
6.79
331.1
175.9
1
0
0
1
1
0
1
0.87
1
145.8
90.6
145.8
90.6
55.2
109
1
1
1
null
0
0
1
0.5
0.5
1
Low
0
47.11
0
0
0
0
0
0.621
1
1.37
554.6
0.0078
22.4
31.7
1
1.88
6.85
6.46
3.21
273
123.7
8.5
0
17.9
8
35.5
1.052
0
0
4.9
0
0
3.14
18.1
0
1.5
0
3
1
17
Current
5
Mediterranean
74.3
Sedentary
8
18.9
17.5
1,129
4.9
Combined
DASH
80.7
530
7.6
1
95.3
0
0
0
2
0
1
0
0
16,969
78.3
0.913
R73.09
2345-7
4548-4
8480-6
HC005-00000002
HC-END-005
39.5
Male
Other
Medicaid
6
0
1
0
Metabolically_Healthy
0
0
0.345
1
0
23.6
74.8
178.2
83.8
1.14
21.2
50
176.9
5.14
43.6
0
342.4
186.8
47.8
539.1
107.8
294.6
129.9
5
80
11.28
200
1
0
0
null
0
0
0
0
0
90.8
4.9
18.6
4.16
232
141.8
0
0
0
0
0
0
0
1
1
126.4
80.3
126.4
80.3
46.1
95.6
1
0
0
null
0
0
1
0.5
1.31
1.27
Low
0
23.17
0
0
0
0
0
0.711
2
6.07
76.9
0.001
23.6
42.1
1
2.85
4.21
5.71
4.29
303.4
119.2
43.8
1
25.2
32.7
70.6
2.575
0
0
7.9
1
0
3.73
22.1
0
3.2
0
0
0
8
Former
4
Mixed
61.2
Very_Active
330
42.5
13.1
16,000
8.3
Control
null
74.6
630
1.26
0
71.8
0
0
0
3
0
0
1
0
9,930
81
1
R73.09
2345-7
4548-4
8480-6
HC005-00000003
HC-END-005
61
Female
Hispanic
Medicaid
9
0
1
0
Metabolically_Healthy
0
0
-0.432
0
0
24
63.4
162.7
84.6
1.06
37.4
81.8
499.4
7.13
105.7
0
200.4
129.7
50.7
100.2
20
149.7
80.4
7.7
34.1
1.98
45.5
0
0
1
Pravastatin
40
0
0
0
0
89.1
5.1
6.2
1.37
82.4
181.3
0
0
0
0
0
0
0
1
1
110.4
74.8
110.4
74.8
35.6
86.6
0
0
0
null
1
0
0
0.5
0.55
1
Low
0
27.58
0
0
0
0
0
0.738
37
0.8
291.4
0.0042
22.8
45.3
1
42.16
11.8
6.36
23.41
263.9
93.5
7.8
0
37.6
29.3
59.7
2.918
0
0
8.4
1
0
1.78
10.9
0
3.9
0
8
0
15
Never
2
Low_carb
59.7
Active
274
28.3
14.1
16,000
7.6
Pharmacotherapy
null
83.6
569
6.03
0
66.7
0
0
0
1
0
0
1
0
1,500
76.1
0.948
R73.09
2345-7
4548-4
8480-6
HC005-00000004
HC-END-005
63.3
Male
Black
Medicaid
6.6
0
1
0
Metabolically_Healthy
0
0
0.445
2
0
29.4
92.3
177.1
92.1
1.12
33.7
99.2
414.3
9.17
33.2
0
200.5
157.4
20
115.9
23.2
180.5
109.7
8.2
42
5.79
52.7
0
1
0
null
0
0
0
0
0
83.9
5.3
39.7
8.22
450
136.6
0
0
0
0
0
0
0
1
1
153.5
95.6
144.7
85.3
57.8
114.9
1
1
1
ARB
0
1
0
0.5
0.78
4.43
Low
0
43.52
0
0
0
0
0
0.825
9
2.17
99.3
0.0013
20.4
51.9
1
4.81
23.19
4.46
32.83
110.5
82.3
5.3
0
27.6
13
52.6
1.56
0
0
6.6
0
0
2.58
9.3
0
2
1
9
0
0
Current
0
Western
27
Very_Active
403
36.3
11.1
16,000
5.4
Pharmacotherapy
null
43.1
150
6.27
0
84.9
0
0
0
6
0
0
1
0
12,928
94.7
0.956
R73.09
2345-7
4548-4
8480-6
HC005-00000005
HC-END-005
30
Male
White
Private
5.9
0
0
0
Metabolically_Healthy
0
0
-0.301
1
0
23.8
81.7
185.1
91.1
1.1
19.3
50
203.2
5.56
46.3
0
203.7
115.9
54.4
166.8
33.4
149.3
81
16.5
28.6
3.07
75.8
1
0
0
null
0
0
0
0
1
78.6
4.6
11.9
2.3
257.6
129
0
0
0
0
0
0
0
1
1
117.4
79.9
95.9
75.1
37.5
92.4
0
0
0
Beta-blocker
1
0
1
0.5
0.5
3.25
Low
0
24.51
0
0
0
0
0
0.666
134
4.29
217.5
0.0052
22.1
21.8
0
1.21
2.93
7.9
7.88
344.3
117.6
227.4
1
52.5
47.4
40.4
1.96
0
0
5.4
0
0
1.37
10.8
0
0.7
0
1
0
15
Former
7
Low_carb
45.8
Sedentary
33
29.8
18.9
3,161
6.9
Lifestyle
DASH
94.9
701
8.83
0
81.8
0
0
0
4
0
0
0
0
15,456
56.8
0.902
R73.09
2345-7
4548-4
8480-6
HC005-00000006
HC-END-005
36.4
Female
Other
Private
4.3
0
1
2
Established_MetS
1
1
0.829
4
3.5
36.4
101.5
167
121.8
1.06
46.6
120.1
511.6
7.8
85.1
1
174.3
86.7
48.2
197.2
39.4
126.1
56.6
178.2
27
4.09
89.6
1
1
0
null
0
1
42.1
11.6
0
89.9
4.9
49.2
10.92
450
200.3
0
0
0
0
0
0
0
1
1
188.7
100
168.9
92.2
88.7
129.6
1
1
1
ARB
0
0
1
0.5
0.58
1
Low
0
38.96
0
0
0
0
0
0.705
5
6.81
1,648.1
0.0026
18.5
73
1
4.38
10.06
3.5
5.25
269
118.6
170.8
1
57.9
48
30.6
2.292
1
1
7.7
1
0
1.91
25.1
0
3.6
1
11
0
19
Former
3
Ultra_processed
26.1
Very_Active
365
38.6
11.6
16,000
6.4
Lifestyle
Mediterranean
79.1
228
5.18
0
88.8
0
0
0
16
0
1
1
1
71,192
82.1
0.831
E88.81
2345-7
4548-4
8480-6
HC005-00000007
HC-END-005
53.5
Female
White
Medicare
5.6
0
0
0
Metabolically_Healthy
0
0
0.068
1
0
30.5
80.8
162.9
84.2
1.13
43.5
56.2
519
6.36
29
0
293.7
100
66.8
634.2
126.8
226.9
71.5
7.2
41
9.49
200
1
0
0
null
0
0
0
0
0
89.3
5.3
17.1
3.76
224.7
159.4
0
0
0
0
0
0
0
1
1
109.2
68.5
97
57.6
40.7
82.1
0
0
0
ARB
1
0
0
0.5
0.5
1
Low
0
20.27
0
0
0
0
0
0.736
0
4.42
111.1
0.0339
19.9
73.5
1
1.9
2.09
2.65
2.67
301.3
102.3
11.7
0
20.7
12.6
109.2
1.486
0
0
7.6
1
1
7.71
13
0
1.7
0
5
0
11
Former
3
Mixed
55.7
Active
287
24.4
10.4
16,000
6.9
Combined
Intensive
84
632
11.73
0
88.1
1
1
1
3
0
0
0
0
4,561
82.7
1
R73.09
2345-7
4548-4
8480-6
HC005-00000008
HC-END-005
48.2
Female
Black
Private
4.9
0
1
1
Early_MetS
1
1
0.972
3
3.1
41.8
116.2
166.7
134.8
1.04
55.9
217
560
10.67
79
1
319.2
139.2
81.2
494.2
98.8
238
81.3
6.9
57.1
6.09
200
1
0
1
Pravastatin
50
0
0
0
0
98.6
5.3
20.1
4.9
198.1
166.2
0
0
0
0
0
0
0
1
1
188.6
119.8
188.6
119.8
68.7
140
1
1
1
null
0
1
0
0.5
2
1
Low
0
20.2
1
0
0
0
0
0.708
0
2.75
405.4
0.0283
18.1
90.1
1
5.2
7.2
3.08
23.09
284.5
100.6
2.5
0
53.9
43.5
10
2.859
1
0
8.5
1
0
1.65
10
0
1.7
1
10
0
15
Never
5
Low_carb
52.5
Low
76
17.7
19.4
7,120
6.8
Pharmacotherapy
null
23.4
160
6.38
0
74.5
1
1
1
6
0
0
0
0
24,955
72
0.901
E88.81
2345-7
4548-4
8480-6
HC005-00000009
HC-END-005
51.8
Male
Hispanic
Private
3.8
0
1
0
Metabolically_Healthy
0
0
0.286
1
0
40.8
127.2
176.5
140.1
1.06
44.7
226.5
481.6
10.59
190.8
1
170.5
98.7
48.3
117.4
23.5
122.2
67.4
5.8
33.3
2.43
53.4
0
0
0
null
0
0
0
0
1
91.5
4.9
10.4
2.34
126.3
154.6
0
0
0
0
0
0
0
1
1
91.6
56.6
73.3
45.6
35
68.3
0
0
0
CCB
1
0
1
0.5
0.5
1
Low
0
73.79
0
0
0
0
0
0.786
1
1.74
175.7
0.0168
24.3
32.4
1
4.88
2.77
3.61
24.19
214.2
104.1
1
0
62.9
49.1
19
3.206
0
0
8.1
1
0
3.94
17.8
0
2.8
1
3
1
19
Never
2
Western
40.2
Moderate
185
26.2
16.9
16,000
7.4
Pharmacotherapy
null
53.8
431
6.73
0
95.6
0
0
0
2
0
0
0
0
6,034
78
0.921
R73.09
2345-7
4548-4
8480-6
HC005-00000010
HC-END-005
41.8
Female
Hispanic
Private
4.9
0
1
1
Early_MetS
1
1
0.11
3
4.7
28.7
77.5
164.3
99.8
1.08
38.7
81.6
386.5
5.87
62.2
1
134
55
50.4
143.1
28.6
83.6
50
40.4
14.5
2.84
65
0
0
0
null
0
0
0
0
0
115.1
6.1
37.4
10.63
253.4
199.4
0
1
1
1
0
0
0
1
1
130.4
76.6
119.3
66.2
53.8
94.5
1
1
1
ACEi
1
1
1
0.5
1.19
1
Low
0
46.84
0
0
0
0
0
0.534
64
6.9
51.5
0.0484
20.2
63
1
2.12
13.87
2.28
1.19
410
78.9
25.6
0
31
28.7
52.2
2.153
1
1
7.9
1
0
0.95
4
0
1.5
1
17
1
26
Never
5
Ultra_processed
25.1
Sedentary
16
29.4
15
1,546
8.4
Combined
DPP_standard
67.7
417
9.26
1
90.1
1
1
0
6
0
0
1
0
17,964
78.9
0.949
E88.81
2345-7
4548-4
8480-6
HC005-00000011
HC-END-005
62.6
Female
Black
Private
5.9
0
1
0
Metabolically_Healthy
0
0
-0.303
1
0
26.1
65.4
158.2
79.1
1.12
40.3
51.9
465.6
5.39
42.3
0
183.3
114.9
43.2
125.8
25.2
140.1
99.9
19.2
31.4
2.91
57.2
0
1
1
Rosuvastatin
50
1
29.6
15.9
0
94.3
5
21.6
5.03
240.4
182.7
0
0
0
0
0
0
0
1
1
115
79.1
98.5
72.6
35.9
91.1
0
0
0
ACEi
1
1
1
0.5
0.5
2.61
Low
0
66.39
0
0
0
0
0
0.703
0
1.32
108
0.0056
21.1
45.4
1
19.23
5.59
1.68
1.61
292.8
97.4
55.3
1
77.3
57.5
148.2
4.09
0
0
5.2
0
1
3.44
11.2
0
0.9
1
17
0
26
Current
8
Low_carb
48.8
Low
72
22.6
17.2
6,972
7
Control
null
79
468
-0.24
0
91
0
0
0
2
0
0
0
0
11,847
59.5
0.97
R73.09
2345-7
4548-4
8480-6
HC005-00000012
HC-END-005
61.3
Male
Hispanic
Medicare
3.8
0
1
1
Early_MetS
1
1
0.178
3
1.2
32.6
97.7
173
109.9
1.06
37.1
180.2
344.1
7.75
26.9
1
302.8
182
75.6
226.2
45.2
227.3
123.2
7.5
80
2.99
102.8
1
0
0
null
0
0
0
0
0
84.6
5.6
38.3
8.01
450
180.4
0
0
0
0
0
0
0
1
1
176.9
109.4
157.9
103.9
67.4
131.9
1
1
1
ARB
0
0
0
0.5
1.86
1
Low
1
5.11
0
0
0
0
0
0.75
60
1.34
100.5
0.0364
19.9
66.7
1
4.01
21.37
8.8
12.22
321.6
103.6
16.6
0
24.5
23.9
25.7
2.965
1
1
8
1
0
1.78
23.1
0
3
0
2
1
20
Former
3
Mediterranean
78
Moderate
86
24.6
19.2
9,195
7.2
Pharmacotherapy
null
62
455
5.36
0
82.1
1
1
0
6
0
0
1
1
92,537
72.2
0.773
E88.81
2345-7
4548-4
8480-6
HC005-00000013
HC-END-005
52.8
Female
Asian
Medicaid
3.7
0
1
1
Early_MetS
1
1
0.376
3
2.2
22.2
63.7
169.3
90.6
1.06
33.4
80.9
331.8
5.8
30.5
1
206.5
131.6
54.6
101.1
20.2
151.9
83.4
13.5
33.5
1.85
46
0
0
1
Pravastatin
30
0
0
0
1
220.5
7.6
16.1
8.74
36.5
277.2
1
0
1
0
1
1
0
0.87
0.65
134.6
86.9
122.8
80.3
47.7
102.8
1
1
1
Combo
0
0
1
0.5
0.5
1
Low
0
30.06
0
0
0
0
0
0.614
0
10.23
24.9
0.1546
18.3
63.4
1
2.48
6.23
15.74
13.54
240.5
97.8
1
0
26.5
26.8
27.8
2.751
0
0
5.4
0
1
3.98
11.2
0
0.7
0
3
0
17
Current
2
Ultra_processed
36
Sedentary
32
19.4
16.9
3,697
8.4
Combined
Intensive
59.4
221
8.1
0
91.1
1
0
0
4
0
1
1
0
24,755
59.9
0.781
E88.81
2345-7
4548-4
8480-6
HC005-00000014
HC-END-005
65.5
Male
Hispanic
Private
2.5
1
1
0
Metabolically_Healthy
0
0
-0.228
1
0
23.9
62.7
161.9
73.6
1.13
27.6
50
381.9
5.54
8.2
0
166.3
115.1
34.8
81.7
16.3
131.5
66.1
8.4
29.9
2.35
37.1
0
1
1
Atorvastatin
50
0
0
0
0
98.7
5.3
13.8
3.35
134.9
151.9
0
0
0
0
0
0
0
1
1
124.3
78.5
112.3
69
45.8
93.8
0
0
0
CCB
1
0
0
0.5
0.5
1
Low
1
6.41
0
0
0
0
0
0.775
147
4.1
217.6
0.0673
21.4
4
0
1.26
5.83
9.17
7.52
383.6
107.4
12
0
29.2
23.7
10.6
2.874
0
0
2.5
0
0
1.06
14.7
0
0.2
0
4
0
20
Never
9
DASH
62.6
Very_Active
301
30.5
14.5
16,000
6
Combined
DASH
69.2
384
9.79
0
59.8
0
0
0
2
0
0
1
0
6,273
55.5
0.84
R73.09
2345-7
4548-4
8480-6
HC005-00000015
HC-END-005
57.6
Male
Black
Medicare
6.4
0
1
0
Metabolically_Healthy
0
0
0.214
2
0
19.7
63
178.9
75.6
1.06
20.7
50
235.6
5.01
13.7
0
231.2
170.7
32.3
141.3
28.3
198.9
124.8
27.8
49.3
4.38
64.2
0
1
0
null
0
0
0
0
1
175.4
7.5
21.4
9.27
67.9
220.8
1
0
1
0
0
0
0
1
1
115.6
76.6
106.7
68.8
38.9
89.6
0
0
0
CCB
1
0
0
0.5
0.5
1
Low
1
2.67
0
0
0
0
0
0.724
1
4.24
273.9
0.0671
18.8
41.6
1
1.68
2.85
4.18
10.68
280.8
112.2
4.9
0
26.4
28.1
21.4
3.154
0
0
5.2
0
0
1.52
17.5
0
2
1
18
0
32
Current
7
Mixed
48.8
Very_Active
450
42.8
12.7
16,000
5.5
Control
null
55.4
285
0.73
0
61.4
0
0
0
2
0
1
0
1
76,893
85.2
0.695
R73.09
2345-7
4548-4
8480-6
HC005-00000016
HC-END-005
41.7
Female
White
Medicaid
6.7
0
1
0
Metabolically_Healthy
0
0
-0.421
1
0
21.7
57.6
163.1
83.7
1.12
30.2
125.8
332.9
5.24
65.4
0
158
88.9
51.3
88.6
17.7
106.6
56.8
300
17.2
1.73
40.3
0
0
1
Simvastatin
40
1
45.8
11.4
0
85.9
6.3
38.3
8.13
450
187
0
1
0
1
0
0
0
1
1
119.5
85.7
107
81.3
33.8
96.9
1
0
1
ACEi
0
1
0
0.5
0.5
1.94
Low
1
8.79
0
0
0
0
0
0.661
64
5.11
327.6
0.0133
24.3
53.5
1
1.23
12.25
1.65
9.02
289.2
101
12
0
23.2
14.8
68.9
1.286
0
0
5.2
0
1
2.59
17.5
1
13.5
0
1
0
22
Never
7
Mixed
31.8
Active
229
35.9
14.7
16,000
7.4
Combined
Mediterranean
69.2
336
10.06
1
78.5
0
0
0
4
0
0
1
0
5,632
63.7
0.878
R73.09
2345-7
4548-4
8480-6
HC005-00000017
HC-END-005
56.4
Male
Hispanic
Medicaid
6
0
0
0
Metabolically_Healthy
0
0
-0.208
1
0
21
74.8
188.8
80.7
1.09
22
50
168
5.32
21.3
0
130
40
38
104.5
20.9
92
50
36.8
12.3
2.75
47.5
0
1
1
Pravastatin
30
0
0
0
0
90.8
5.1
28.6
6.41
357.1
157.4
0
0
0
0
0
0
0
1
1
120.5
77.7
120.5
77.7
42.8
92
0
0
0
null
1
0
0
0.5
0.5
1
Low
0
45.42
0
0
0
0
0
0.738
11
2.7
669.6
0.0067
23.3
9.2
0
3.14
13.18
6.96
11.2
397
104.3
141.2
1
17.2
10.1
155.5
1.372
0
0
6.3
0
0
0.63
13.3
1
32.7
0
0
0
20
Never
7
Western
25.7
Sedentary
1
26.6
20
847
5.1
Control
null
83.9
389
0.52
0
70.7
0
0
0
8
0
0
0
0
14,004
88.7
0.927
R73.09
2345-7
4548-4
8480-6
HC005-00000018
HC-END-005
40.5
Male
Hispanic
Medicaid
7.6
0
1
1
Early_MetS
0
1
0.327
3
4.7
29.9
80.4
163.9
101.8
1.07
29
106.2
292.6
6.52
30.6
0
176.2
88.2
37.2
253.7
50.7
139
61.8
18.1
35.9
6.81
115.3
1
1
1
Simvastatin
50
0
0
0
0
103.1
5
15.6
3.98
136.8
180
0
0
1
0
0
0
0
1
1
114.5
78.3
104.3
74
36.2
90.4
0
0
0
ARB
1
0
1
0.5
3.44
3.77
Low
0
15.47
0
0
0
0
0
0.733
28
0.78
385.9
0.0033
24.3
58.1
1
1.7
18.24
1.79
5.37
111.9
102.6
28.6
0
14
9.6
27
1.035
0
0
7.8
1
0
2.92
18.7
0
3.9
0
9
0
26
Current
2
Mediterranean
73.1
Moderate
158
29.7
16.7
15,281
5.6
Pharmacotherapy
null
89.7
514
8.21
0
82.5
1
1
0
6
0
0
1
0
14,349
75.2
0.918
E88.81
2345-7
4548-4
8480-6
HC005-00000019
HC-END-005
62.5
Female
White
Medicare
5.7
0
1
0
Metabolically_Healthy
0
0
-0.629
1
0
21
59.1
167.8
72.4
1.16
34.2
50
413.4
5.28
19
0
223.9
148.6
54.3
104.8
21
169.6
104.8
9.7
45.9
1.93
47.7
0
0
0
null
0
0
0
0
0
100.9
5.4
4
0.99
36.7
133.7
0
0
1
0
0
0
0
1
1
106
67.9
84.7
60.6
38.1
80.6
0
0
0
CCB
1
0
0
0.5
0.5
1
Low
0
68.33
0
0
0
0
0
0.825
13
3.71
63.6
0.0835
22.1
27
0
7.44
14.84
5.64
10.86
279.9
71.3
21.3
0
31.5
18.7
16.8
2.078
0
0
6.2
0
1
4.79
23.2
0
3.8
0
4
0
18
Former
1
Western
38
Active
291
32.7
13.4
16,000
8.4
Pharmacotherapy
null
77.8
511
5.68
0
77.1
0
0
0
3
0
0
0
0
10,829
69.9
0.927
R73.09
2345-7
4548-4
8480-6
HC005-00000020
HC-END-005
51.4
Female
White
Medicaid
6.4
0
1
0
Metabolically_Healthy
0
0
-0.448
0
0
21.7
56.4
161.2
78.4
1.11
32.5
50
382.3
4.98
27.3
0
190.2
119.9
52.7
88.2
17.6
137.5
85.4
4.6
36.3
1.67
40.1
0
0
0
null
0
0
0
0
0
95.2
4.9
24.8
5.83
269.2
117.2
0
0
0
0
0
0
0
1
1
123.2
74.5
105.1
66.8
48.7
90.7
0
0
0
CCB
1
0
0
0.5
0.5
1.04
Low
0
45.06
0
0
0
0
0
0.707
113
2.9
81.4
0.0017
22.3
64.9
1
2.22
12.34
3.29
6.43
242.8
99.5
9
0
69.9
47.8
37.9
2.938
0
0
9
1
0
0.84
10.7
0
0.6
1
10
0
11
Current
9
Mediterranean
82.6
Sedentary
15
27.8
17.4
1,360
4.5
Lifestyle
Mediterranean
58.2
450
3.69
0
50.3
0
0
0
4
0
0
0
0
3,993
49.6
0.974
R73.09
2345-7
4548-4
8480-6
HC005-00000021
HC-END-005
49.8
Female
Black
Private
6.2
0
1
2
Established_MetS
1
1
0.613
4
2.9
40
105.9
162.7
137.6
1.06
54
212.1
498.7
8.6
87.6
1
196.5
82.7
67.7
230.5
46.1
128.8
55.6
45
39.3
3.4
104.8
1
0
1
Simvastatin
50
0
0
0
0
102.3
4.8
5.3
1.33
47.2
191.7
0
0
1
0
0
0
0
1
1
154.1
97.2
143.3
89.2
56.9
116.2
1
1
1
ARB
0
0
0
0.5
1.17
1
Low
0
27.37
0
0
0
0
0
0.676
10
1.33
675.5
0.0333
18.5
78.3
1
14.08
14.21
1.08
6.02
289.1
86.8
42.6
1
95
51.8
10
2.647
1
0
6.3
0
0
2.65
13.6
0
3.7
0
1
0
21
Former
8
Western
33.2
Moderate
143
22.1
15.5
13,378
7
Lifestyle
DPP_standard
50.7
256
8.27
0
56.5
0
0
0
4
0
1
1
0
26,723
78.2
0.838
E88.81
2345-7
4548-4
8480-6
HC005-00000022
HC-END-005
43.8
Female
Black
Medicare
5.3
0
1
1
Early_MetS
1
1
0.166
3
3.8
40.7
85.7
145
91.1
1.12
53.6
115
616.7
8.4
26.5
1
291.9
88.4
82.6
604.4
120.9
209.2
60.5
42.4
31.7
7.31
200
1
0
0
null
0
0
0
0
0
89.2
5.1
14.6
3.2
192.9
137.8
0
0
0
0
0
0
0
1
1
149
92.9
133.6
87.8
56.1
111.6
1
1
1
ACEi
0
0
1
0.5
0.5
1
Low
0
73.18
0
0
0
0
0
0.663
0
1.08
200.8
0.0223
19.9
66.9
1
5.74
15.29
18.38
2.5
301.8
102.9
3.5
0
38.6
31.2
112.8
2.199
1
0
4.2
0
0
1.49
15.5
0
0.4
1
12
0
19
Never
8
DASH
64.9
Sedentary
16
16.8
16.6
2,579
4.9
Control
null
50.4
249
1.14
0
90.1
0
0
0
4
0
0
0
0
16,550
83.3
0.832
E88.81
2345-7
4548-4
8480-6
HC005-00000023
HC-END-005
66.7
Female
Black
Private
4.3
0
1
0
Metabolically_Healthy
0
0
-0.4
1
0
21.4
54.6
159.6
60
1.14
35.6
50
427.1
5.24
1.5
0
130
60.9
26.7
132.5
26.5
103.3
50
12
16.5
4.96
60.2
0
1
1
Simvastatin
50
0
0
0
0
87.1
5.4
13.1
2.82
188.3
111.2
0
0
0
0
0
0
0
1
1
107.2
71.7
107.2
71.7
35.6
83.5
0
0
0
null
1
1
1
0.5
2.07
1.66
Low
0
44.62
0
0
0
0
0
0.802
50
2.82
125.3
0.0016
24.2
78.9
1
6.58
17.82
2.34
9.54
294.9
101.5
20.7
0
72.5
49.5
11.2
3.878
0
0
6.4
0
0
1.51
19.5
0
1.4
0
7
1
16
Never
4
Western
43.7
Moderate
110
27.1
13.9
9,822
7.1
Lifestyle
Intensive
73.1
150
8.95
0
63.9
0
0
0
5
0
0
1
0
6,469
89.1
1
R73.09
2345-7
4548-4
8480-6
HC005-00000024
HC-END-005
50.1
Male
White
Medicare
10
0
0
0
Metabolically_Healthy
0
0
-0.388
2
0
19.4
61.4
177.8
60
1.15
18.6
50
260
5.95
0
0
226.8
194.8
20
60
12
206.8
133.2
76.3
48.7
3
27.3
0
1
0
null
0
1
37.3
8.4
1
119.7
9.7
5.4
1.58
33.4
180.5
1
0
1
0
1
1
0
0.87
0.65
88
55.9
88
55.9
32.1
66.6
0
0
0
null
1
0
0
0.5
0.5
1
Low
0
34.29
0
0
0
0
0
0.906
337
0.84
46.4
0.0438
17.3
5.9
0
8.22
3.04
4.6
20.7
231.3
99.8
7.4
0
29.5
15.5
47.6
1.428
0
0
5
0
0
1.53
16.2
0
0.3
0
4
1
22
Current
6
Ultra_processed
2.7
Moderate
85
25.2
14.8
8,518
8.8
Control
null
84.5
650
4.76
0
82.9
0
0
0
1
0
1
1
0
20,458
76.9
0.965
R73.09
2345-7
4548-4
8480-6
HC005-00000025
HC-END-005
46.9
Male
White
Medicare
4.5
0
1
0
Metabolically_Healthy
0
0
-0.081
0
0
34.4
96
167.2
97.4
1.09
35.8
88.7
376.8
7.72
65.8
0
269
196.2
47
129.3
25.9
222.1
134.9
20.6
54.8
2.75
58.8
0
0
0
null
0
0
0
0
0
95.6
5.1
18.4
4.34
196.4
188
0
0
0
0
0
0
0
1
1
116.4
68.1
100.5
58.5
48.3
84.2
0
0
0
CCB
1
0
1
0.5
0.5
1
Low
0
48.63
0
0
0
0
0
0.569
20
2.58
69.2
0.0081
21.4
39.4
1
21.71
6.59
5.46
8.47
281.1
93.4
3.1
0
14.1
8
47
0.999
0
0
5.1
0
0
2.81
15.4
0
3.3
0
4
0
3
Former
5
Western
55.3
Active
334
40.3
12.1
16,000
5.4
Lifestyle
Mediterranean
89.4
309
8.83
0
75.6
0
0
0
5
0
0
0
0
7,592
43.7
0.88
R73.09
2345-7
4548-4
8480-6
HC005-00000026
HC-END-005
47.8
Male
White
Private
4
0
1
0
Metabolically_Healthy
0
0
-0.132
2
0
20.8
67.5
180.2
80.4
1.11
19.7
50
132
4.98
24.6
0
186.3
124.9
33.8
138.1
27.6
152.5
92.4
47.1
23.4
4.09
62.8
0
1
0
null
0
1
40.3
6.3
1
106.1
5.7
62.5
16.38
450
214
0
0
1
0
0
0
0
1
1
106.1
65.4
96.6
53.8
40.7
79
0
0
0
Combo
1
0
0
0.5
2.83
1
Low
0
56.52
0
0
0
0
0
0.617
0
2.31
251.1
0.0023
25.5
22
0
1.75
2.84
4.22
8.29
314.4
106.5
29.7
0
22.5
19.2
63.9
1.929
0
0
5.5
0
1
9.26
8.3
0
0.9
1
13
1
13
Former
8
Western
36.8
Low
39
20
19
4,216
4.1
Lifestyle
DASH
73.5
457
6.89
0
76.4
0
0
0
2
0
0
0
0
10,386
89.1
1
R73.09
2345-7
4548-4
8480-6
HC005-00000027
HC-END-005
58.4
Male
Black
Medicaid
6.5
0
1
1
Early_MetS
1
1
0.68
3
3.7
32.5
94.4
170.4
108.1
1.08
36.3
99.1
365.6
9.47
84.3
1
143
95
21.4
133.1
26.6
121.6
64.1
27.8
18.9
6.22
60.5
0
1
1
Rosuvastatin
30
0
0
0
0
89.8
5.2
11.5
2.54
148.3
130.5
0
0
0
0
0
0
0
1
1
150.7
85.3
139.7
79.2
65.4
107.1
1
1
1
ARB
0
1
1
0.5
1.68
3.82
Low
0
47.99
0
0
0
0
0
0.668
111
2.64
13.4
0.0172
21
42
1
7.86
11.73
8.55
29.63
236.7
122.8
1
0
27.8
26.8
45.1
2.966
0
0
5.5
0
0
2.27
10.3
0
2.7
0
4
0
10
Never
3
Western
45.3
Active
200
25.8
15.3
16,000
7
Lifestyle
DASH
57.1
339
9.5
0
89.3
1
0
0
7
0
0
0
0
17,081
54.4
0.968
E88.81
2345-7
4548-4
8480-6
HC005-00000028
HC-END-005
56.4
Female
Asian
Private
6.1
0
1
0
Metabolically_Healthy
0
0
-0.14
1
0
20.6
53.3
161
75.8
1.13
32.2
50
328.1
6.58
17.1
0
204.3
61.4
52.7
450.7
90.1
151.6
50
16.5
33.6
8.55
200
1
0
1
Pravastatin
55
0
0
0
0
81.6
5.2
24.1
4.85
441.5
140.6
0
0
0
0
0
0
0
1
1
108.1
67
98
61.7
41.1
80.7
0
0
0
CCB
1
0
1
0.5
0.5
1
Low
0
89.95
0
0
0
0
0
0.764
41
4.27
8.5
0.0041
23.6
55.7
1
5.29
30.11
3.44
24.68
385.3
72.9
4.5
0
20
17.3
35.6
2.187
0
0
4.9
0
0
1.04
17
1
20
0
5
0
11
Never
5
Mediterranean
71.6
Sedentary
31
31.4
17.8
1,635
5.8
Lifestyle
Mediterranean
40.7
284
3.33
0
77
0
0
0
9
0
0
0
0
5,297
59.1
0.955
R73.09
2345-7
4548-4
8480-6
HC005-00000029
HC-END-005
57
Male
White
Private
2.4
1
1
1
Early_MetS
1
1
0.354
3
4.2
28.7
84.1
171.3
105.7
1.08
31.3
125.7
367.2
10.06
69
1
257.1
149.4
50.3
287
57.4
206.8
99
7
69.1
5.71
130.5
1
0
0
null
0
0
0
0
0
82.7
4.9
71.8
14.67
450
163.9
0
0
0
0
0
0
0
1
1
145
92.3
134.6
87.7
52.7
109.8
1
1
1
CCB
0
0
0
0.5
0.5
3.33
Low
0
34.49
0
0
0
0
0
0.764
32
5.22
285.4
0.0087
20.9
43.9
1
9.53
17.67
8.03
43.28
320.9
96.4
22.4
0
45.4
33.7
53
2.847
0
0
8.7
1
0
2.01
13.4
0
1.5
1
16
0
16
Current
4
Western
25.1
Moderate
128
33.8
20
11,614
6.4
Pharmacotherapy
null
76
317
2.31
0
88
1
1
0
5
0
0
0
0
9,154
65
0.848
E88.81
2345-7
4548-4
8480-6
HC005-00000030
HC-END-005
57.2
Male
Black
Private
8
0
1
0
Metabolically_Healthy
0
0
0.092
2
0
25.8
81.1
177.4
96
1.11
27.9
160.6
177.9
10.66
18.6
0
257.1
191.9
47.1
90.6
18.1
210
134.6
17.1
52
1.92
41.2
0
0
0
null
0
1
49.7
11
0
104.1
5.3
25.7
6.61
220.1
153.3
0
0
1
0
0
0
0
1
1
146
105.5
146
105.5
40.4
119
1
1
1
null
0
1
0
0.5
0.5
2.11
Low
0
38.09
0
0
0
0
0
0.701
18
1.53
68.9
0.0061
18.2
53.7
1
4.1
5.93
7.65
55
278
92
52.3
1
57.7
50.3
77.5
3.79
0
0
6.4
0
0
2.6
14.3
0
3.2
0
3
0
10
Current
5
Ultra_processed
17.3
Active
357
35.6
15.4
16,000
7
Control
null
56.3
357
1.05
0
80.1
0
0
0
4
0
0
1
0
19,938
76.2
0.902
R73.09
2345-7
4548-4
8480-6
HC005-00000031
HC-END-005
75
Male
White
Medicare
5.3
0
1
2
Established_MetS
1
1
0.896
4
3.2
40.7
121.8
173.1
133.9
1.02
49.9
211
517
9.28
73.4
1
156.7
46.8
49.5
301.5
60.3
107.1
50
50.7
16.5
6.09
137
1
0
1
Atorvastatin
50
0
0
0
0
102.5
5.4
9.1
2.31
81.1
179.6
0
0
1
0
0
0
0
1
1
148.1
103.7
148.1
103.7
44.4
118.5
1
1
1
null
0
0
1
0.5
5.65
3.33
Low
0
75.96
0
0
0
0
0
0.926
108
6.56
440
0.0039
15
66.6
1
18.95
13.31
2.13
11.49
48
79.8
46.1
1
14.7
8
190.5
1.564
1
0
6.7
0
0
3.26
15.7
0
1.3
0
0
0
31
Never
4
Mediterranean
65.2
Moderate
156
22.7
13.6
14,433
7.3
Combined
DPP_standard
51.4
408
13.58
0
61.4
1
0
0
5
0
1
0
0
30,335
90.6
0.742
E88.81
2345-7
4548-4
8480-6
HC005-00000032
HC-END-005
47.1
Male
White
Private
3.1
1
1
0
Metabolically_Healthy
0
0
-0.199
0
0
25.7
79
175.2
91.7
1.13
25.5
100.8
333.1
5.59
51.6
0
171.7
99.8
50.9
105
21
120.8
52.6
11.5
22.5
2.06
47.7
0
0
1
Rosuvastatin
40
0
0
0
0
95
5.6
16.7
3.92
182.7
141.9
0
0
0
0
0
0
0
1
1
124.7
71.8
124.7
71.8
52.9
89.4
0
0
0
null
1
0
1
0.5
0.5
1
Low
0
53.74
0
0
0
0
0
0.716
0
2.41
793.7
0.0027
18.8
13.5
0
1.18
11.88
7.19
4.39
268.3
102.8
3.8
0
26.1
21.4
12.7
1.968
0
0
8.6
1
0
0.86
27.7
0
0.6
1
20
0
21
Never
7
Mixed
29.5
Active
217
36
15.8
16,000
7.3
Lifestyle
DPP_standard
50.5
295
6.09
0
82.8
1
1
1
7
0
0
0
0
4,406
57.1
1
R73.09
2345-7
4548-4
8480-6
HC005-00000033
HC-END-005
45.9
Female
White
Medicare
8.1
0
0
1
Early_MetS
1
1
-0.076
3
2.8
32.2
77.9
155.5
94.6
1.11
43.8
70.5
505
7.17
56.2
1
196.2
101.8
56.5
189.4
37.9
139.7
75.6
32.6
29.5
3.35
86.1
1
0
1
Rosuvastatin
40
1
37.9
14.5
0
90.8
5
19.8
4.44
246.8
126.3
0
0
0
0
0
0
0
1
1
134
86.5
112.2
77.7
47.5
102.3
1
1
1
Beta-blocker
1
0
1
0.5
2.78
1
Low
0
101.39
0
0
0
0
0
0.754
41
14.8
39.6
0.0289
17.4
79.2
1
1.53
10.92
2.72
7.26
339.7
97.3
9
0
8
8
10
1.297
0
0
6.2
0
0
1.52
13.5
0
1.8
0
6
0
11
Never
8
Western
30.9
Moderate
110
24.7
13.8
10,363
6.6
Control
null
73.8
308
0.51
0
78.2
1
0
0
2
0
0
1
0
23,604
83.8
0.875
E88.81
2345-7
4548-4
8480-6
HC005-00000034
HC-END-005
42.2
Male
White
Private
6.9
0
1
0
Metabolically_Healthy
0
0
0.041
0
0
25.4
84.7
182.6
100.2
1.1
24
92
296.5
6.81
106.5
0
210
145
40.4
122.8
24.6
169.6
109.3
6.1
38.9
3.04
55.8
0
0
0
null
0
1
34.9
7
0
94.7
5.3
38.1
8.9
420
160.1
0
0
0
0
0
0
0
1
1
116.1
75
116.1
75
41.1
88.7
0
0
0
null
1
0
1
0.5
0.5
2.47
Low
0
67.65
0
0
0
0
0
0.754
0
1.72
18.5
0.0164
22.2
41.6
1
2.25
3.58
2.5
17.26
253.2
114
14.4
0
27.2
22.1
10
1.789
0
0
4.4
0
0
3.56
22.9
0
2.8
1
8
0
4
Never
9
Western
44.8
Moderate
187
34.9
15.4
16,000
7.1
Control
null
67.7
223
-0.72
0
86.6
1
1
0
4
0
0
0
0
2,020
60.4
1
R73.09
2345-7
4548-4
8480-6
HC005-00000035
HC-END-005
59.4
Male
Black
Medicaid
2.7
1
1
0
Metabolically_Healthy
0
0
-0.017
1
0
28.3
84.6
172.8
94.8
1.04
31.4
119.8
275.7
9.09
39.8
0
201.6
131.2
46.5
119.4
23.9
155.1
77.8
47.4
44.5
2.57
54.3
0
0
1
Atorvastatin
50
0
0
0
0
79.8
5
32.7
6.45
450
163.5
0
0
0
0
0
0
0
1
1
141.8
88.6
129.8
81.1
53.2
106.3
1
1
1
ARB
0
1
1
0.5
0.5
1
Low
0
44.84
0
0
0
0
0
0.59
0
0.67
92.8
0.0152
23.7
33.1
1
3.48
23.96
7.5
34.28
308
94.4
83.1
1
27
11.5
10
1.32
1
0
4.4
0
1
6.85
22.6
0
0.2
0
7
1
13
Current
4
Ultra_processed
23.3
Very_Active
364
31.3
9.2
16,000
6.4
Combined
DPP_standard
52.6
406
9.91
0
82.4
1
1
1
2
0
0
0
0
10,913
65.4
0.963
R73.09
2345-7
4548-4
8480-6
HC005-00000036
HC-END-005
65.5
Male
Asian
Uninsured
9.4
0
1
3
Refractory_MetS
1
1
1.264
5
14
39.4
110.7
167.7
110
1.11
46.1
198.3
429.7
8.35
64.6
1
284.7
202.4
33.8
242.8
48.6
250.9
136.4
28.3
80
7.19
110.4
1
1
0
null
0
0
0
0
0
110.4
6
3
0.82
22.3
104.9
0
1
1
0
0
0
0
1
1
220
128
199.8
118.1
92
140
1
1
1
ACEi
0
0
1
0.5
0.5
1
Low
0
53.53
0
1
0
0
0
0.852
117
6.35
115.7
0.0072
16.7
90.1
1
6.97
3.92
4.43
4.78
209.2
51.2
85.8
1
192.1
144.9
11.6
6.5
0
0
6.9
0
0
1.58
20
1
10.7
0
8
0
15
Never
1
Mediterranean
64.3
Low
58
10.9
15.8
4,479
6.2
Lifestyle
DPP_standard
65
314
1.47
0
93.1
0
0
0
4
0
1
0
0
35,151
93.7
0.693
E88.81
2345-7
4548-4
8480-6
HC005-00000037
HC-END-005
50.6
Male
White
Medicare
6.9
0
1
1
Early_MetS
0
1
0.456
3
1.7
28.1
86.5
175.5
90.6
1.09
29.1
125.7
369.4
6.96
60.9
0
196.3
116.1
47.1
165.5
33.1
149.2
74.6
5.4
32.8
3.52
75.2
1
0
0
null
0
0
0
0
0
187.2
6.8
7.9
3.64
22.7
240.5
1
0
1
0
0
0
1
1
1
138.8
85.7
129.8
78.2
53.1
103.4
1
1
1
ARB
1
0
1
0.5
0.5
2.42
Low
0
37.84
0
0
0
1
0
0.605
56
4.36
124.2
0.0118
20.4
51.2
1
1.93
7.06
7.98
13.42
282.7
115.5
34.7
1
85.7
91.1
10.3
4.984
1
0
3.9
0
0
1.74
11.8
0
1
0
6
0
12
Never
2
Western
45.7
Moderate
180
31.7
16.3
16,000
6.6
Control
null
81.6
419
1.35
0
88.2
1
0
0
2
0
1
0
0
34,338
68.3
0.895
E88.81
2345-7
4548-4
8480-6
HC005-00000038
HC-END-005
41.9
Female
Hispanic
Medicare
5.5
0
1
1
Early_MetS
0
1
0.114
3
1.1
32.2
73.6
151.3
83.4
1.1
42.8
81.7
493.7
7.02
15.2
0
253.7
105.4
57.5
453.9
90.8
196.2
68.5
15.7
40.5
7.89
200
1
0
1
Pravastatin
55
1
43.2
13.9
1
117.2
6.4
13.5
3.92
88.4
216
0
1
1
0
0
0
0
1
1
115.3
86
115.3
86
29.2
95.8
1
0
1
null
0
0
1
0.5
2.04
1.33
Low
0
18.7
0
0
0
0
0
0.675
6
8.91
238.4
0.0046
20.3
84.9
1
1.55
18.5
8.03
5.85
401.5
119.2
10.5
0
57.5
43
24.1
2.379
0
0
4.9
0
0
1.98
16.7
0
2.7
0
4
0
38
Current
2
Western
37.7
Moderate
83
28.8
15.7
7,677
7.3
Combined
DPP_standard
65.8
611
12.79
0
78
1
1
1
4
0
0
1
0
19,894
86.3
0.981
E88.81
2345-7
4548-4
8480-6
HC005-00000039
HC-END-005
42.1
Male
Black
Medicaid
9
0
1
0
Metabolically_Healthy
0
0
0.453
2
0
32.9
89.5
164.8
100.3
1.08
33
102
369.8
7.57
52.9
0
171.4
89.7
49.8
159.1
31.8
121.6
62.6
56
23.3
3.19
72.3
1
0
1
Simvastatin
60
0
0
0
1
84.3
5.1
7.1
1.47
114.2
162.2
0
0
0
0
0
0
0
1
1
193.1
120.6
171.8
110.4
72.5
140
1
1
1
Combo
0
0
0
0.5
2.07
2.16
Low
0
37.91
1
0
0
0
0
0.651
36
3.92
186.7
0.0045
19.8
64.1
1
2.08
7.03
2.05
9.76
332.7
99.6
2.2
0
14.4
11.8
79
1.304
0
0
6.1
0
0
1.47
14
0
0.5
0
5
0
4
Current
4
Mixed
39.3
Active
266
28.8
11.4
16,000
5.8
Pharmacotherapy
null
38.9
267
6.97
0
62.8
0
0
0
3
0
0
1
0
8,857
78.6
1
R73.09
2345-7
4548-4
8480-6
HC005-00000040
HC-END-005
59.8
Male
Other
Uninsured
5.9
0
0
0
Metabolically_Healthy
0
0
-0.289
0
0
25.1
71.6
168.8
90
1.07
27.7
79.5
264.2
5.99
53.4
0
130
70.7
44.4
60
12
85.6
50
5
20.7
1.35
27.3
0
0
1
Pravastatin
50
0
0
0
0
70
5.2
3
0.52
135
114.1
0
0
0
0
0
0
0
1
1
126.6
82.6
109.5
76.7
43.9
97.3
1
0
0
ACEi
1
0
0
0.5
0.5
1
Low
0
29.78
0
0
0
0
0
0.76
1
25.41
134.9
0.0865
15.7
31.4
1
1
9.77
10.52
9.65
175
97.7
1.4
0
13.8
8
63.8
1.288
0
0
7.9
1
0
2.22
26.1
0
1.6
0
2
1
18
Never
5
Western
34.6
Low
92
24.4
15.1
9,150
6.9
Pharmacotherapy
null
66.7
481
6.88
0
78.6
0
0
0
4
0
0
1
0
1,500
82.2
0.988
R73.09
2345-7
4548-4
8480-6
HC005-00000041
HC-END-005
60.9
Male
Hispanic
Medicare
5.4
0
1
1
Early_MetS
1
1
0.29
3
2.1
32
92.3
170
102.3
1.06
36.2
80.1
413.9
7.87
25.1
1
194.1
94.7
52.9
232.8
46.6
141.3
54.6
6.2
40.8
4.4
105.8
1
0
1
Pravastatin
40
0
0
0
0
137.8
6
8.6
2.93
41
208.8
0
1
1
0
0
0
0
1
1
123.4
60.5
102.4
49.5
62.9
81.5
0
0
0
Beta-blocker
1
0
1
0.5
0.5
3
Low
0
56.97
0
0
0
0
0
0.673
6
2.47
435.4
0.0321
19.8
57.4
1
2.88
10.06
7.46
14.83
119.2
108.6
6.3
0
13
16.4
19.9
2.766
0
0
8.6
1
0
2.16
18.1
0
1.9
0
6
0
16
Current
0
Mediterranean
84.4
Low
80
17.1
14.8
7,869
6
Control
null
77.3
615
1.71
0
52.2
1
1
1
9
0
0
1
0
11,672
94.1
0.853
E88.81
2345-7
4548-4
8480-6
HC005-00000042
HC-END-005
58.5
Female
White
Medicaid
4
0
1
0
Metabolically_Healthy
0
0
-0.536
1
0
23.5
61.3
161.7
76.3
1.13
36.2
50
373.7
10.17
18.7
0
180.3
105.4
59.5
76.9
15.4
120.7
68.2
18.6
27.1
1.29
35
0
0
1
Pravastatin
30
0
0
0
0
85.6
5.1
14.2
2.99
216.6
156.7
0
0
0
0
0
0
0
1
1
137.8
93.3
127.9
83.6
44.5
108.1
1
1
1
ARB
0
0
0
0.5
0.5
1
Low
0
56.24
0
0
0
0
0
0.838
0
7.72
278
0.0057
20.8
56.4
1
3.53
9.67
3.87
54.79
341.3
110.2
25.3
0
88.9
70.5
21.5
4.375
0
0
7.1
1
1
5.7
14.9
0
1.9
1
14
0
16
Former
8
Mixed
59.1
Sedentary
38
21.8
18.2
4,317
5.7
Lifestyle
Mediterranean
77.2
244
4.34
0
84.5
0
0
0
1
0
0
0
0
13,519
65
1
R73.09
2345-7
4548-4
8480-6
HC005-00000043
HC-END-005
44
Female
Hispanic
Uninsured
6.8
0
0
1
Early_MetS
1
1
0.012
3
2.5
29.4
78.4
163.4
98.7
1.08
40
56.8
510.2
7.47
64.8
1
216.3
133.2
50.8
161
32.2
165.4
88.1
209.9
38.9
3.17
73.2
1
0
0
null
0
0
0
0
1
85.5
5.5
9.9
2.09
151.9
123.4
0
0
0
0
0
0
0
1
1
135.4
94.3
116.6
84.3
41.1
108
1
1
1
ACEi
0
1
1
0.5
0.5
3.27
Low
0
91.18
0
0
0
0
0
0.565
191
1.82
103.6
0.0018
19.9
56.3
1
5.49
10.02
5.43
15.97
384.6
119
4.8
0
14.9
8.2
232.8
0.937
0
0
6.5
0
0
1.39
24.9
0
1.1
1
7
0
2
Never
7
Low_carb
49.5
Very_Active
308
34.3
15.3
16,000
7.9
Lifestyle
Intensive
91.8
716
7.69
0
90.1
1
1
1
7
0
0
1
0
13,839
75.6
0.893
E88.81
2345-7
4548-4
8480-6
HC005-00000044
HC-END-005
54.8
Female
White
Medicaid
6.5
0
0
0
Metabolically_Healthy
0
0
-0.483
1
0
28.2
70.1
157.6
87.5
1.15
41.1
66.7
581.8
6.42
48.3
0
152.8
64.1
53.3
177
35.4
99.5
50
9.6
25.5
3.32
80.5
1
0
1
Rosuvastatin
30
0
0
0
0
89
4.8
7.2
1.57
95.5
145.3
0
0
0
0
0
0
0
1
1
88
55
76.7
49.1
33
66
0
0
0
CCB
1
1
1
0.5
0.5
2.98
Low
1
14.37
0
0
0
0
0
0.793
64
4.63
266.8
0.0043
22.3
43.7
1
4.31
10.77
10.75
7.8
149.8
104.4
21.2
0
21.9
12.7
62
1.492
0
0
5.5
0
1
5.69
14.2
0
2.1
0
5
1
17
Current
4
Ultra_processed
32.7
Low
41
26
16.9
4,625
7
Control
null
68.5
548
1.32
0
53.2
0
0
0
5
0
0
1
1
68,003
67.5
0.898
R73.09
2345-7
4548-4
8480-6
HC005-00000045
HC-END-005
53.4
Female
Other
Medicare
5.5
0
1
0
Metabolically_Healthy
0
0
-0.544
2
0
23.9
54.5
151
75
1.12
35.6
50
431.3
5.47
21.6
0
150.4
75.2
46.4
144
28.8
104
56.7
34.6
21.8
3.1
65.5
0
1
1
Simvastatin
60
0
0
0
0
101
5.3
14.6
3.65
134.8
185
0
0
1
0
0
0
0
1
1
88
55
75.2
50.3
33
66
0
0
0
ARB
1
0
1
0.5
0.5
2.28
Low
0
41.83
0
0
0
0
0
0.61
40
5.5
21.4
0.0052
20.1
53
1
18.19
9.73
4.73
6.85
282.9
109.9
3.2
0
15
10.8
41.8
1.481
0
0
6.7
0
0
1.54
18.8
0
1.1
0
3
0
19
Never
5
Mediterranean
71.6
Moderate
111
25.7
18.2
11,383
7.1
Combined
Mediterranean
72.5
350
7.73
0
81.7
1
1
1
5
0
0
1
0
11,787
79.6
0.899
R73.09
2345-7
4548-4
8480-6
HC005-00000046
HC-END-005
54.6
Female
Hispanic
Private
3.8
0
1
0
Metabolically_Healthy
0
0
-0.6
1
0
22.2
54.9
157.2
74.9
1.15
33.8
50
365.8
5.39
32.9
0
157.3
75.4
62.7
96.2
19.2
94.6
50
26.7
26.8
1.53
43.7
0
0
1
Simvastatin
60
0
0
0
0
139.3
7.4
18
6.19
83.8
175
1
0
1
1
1
0
0
0.87
1
99.9
66.1
99.9
66.1
33.8
77.3
0
0
0
null
1
0
0
0.5
0.5
1
Low
0
37.36
0
0
0
0
0
0.73
394
6.34
438.3
0.0126
19.4
57.7
1
7.63
4.81
29.67
9.43
517.6
116.9
4
0
11.6
12.5
39.8
2.014
0
0
8.7
1
0
1.96
19.5
1
14
1
14
0
23
Current
1
Low_carb
77.6
Sedentary
12
19
16.6
1,090
5.5
Control
null
72
477
1.94
1
67.7
0
0
0
3
0
1
1
0
15,952
97.9
0.894
R73.09
2345-7
4548-4
8480-6
HC005-00000047
HC-END-005
62.5
Male
Black
Private
5.8
0
1
0
Metabolically_Healthy
0
0
-0.112
0
0
29
86.6
172.7
95.3
1.1
33
85.5
269.2
6.36
18.4
0
130
65.1
41.8
94.3
18.9
88.2
50
10.5
21.3
2.26
42.9
0
0
1
Pravastatin
50
0
0
0
0
96.2
5.9
10.3
2.44
108.5
149.9
0
1
0
1
0
0
0
1
1
111.8
70.8
98.1
61.6
41
84.5
0
0
0
CCB
1
0
1
0.5
0.5
2.33
Low
0
45.83
0
0
0
0
0
0.923
29
6.02
131.2
0.0128
18.5
43.8
1
7.14
2.99
18.53
5.5
260.3
91.5
67.3
1
37.1
28.5
27.1
2.921
0
0
6.7
0
0
1.88
17.7
0
0.5
0
3
0
21
Former
5
DASH
77.4
Moderate
128
31.2
15.7
12,190
6.3
Control
null
70.6
490
-0.88
1
87
0
0
0
2
0
0
0
0
11,098
55.1
0.991
R73.09
2345-7
4548-4
8480-6
HC005-00000048
HC-END-005
54.7
Male
White
Medicare
5.3
0
0
1
Early_MetS
0
1
0.5
3
2.1
28.7
86.6
173.8
90.9
1.14
30.8
63.4
283.1
6.96
51.9
0
191.8
95.8
49.5
232.3
46.5
142.3
66.5
24
48.5
4.69
105.6
1
0
1
Rosuvastatin
30
0
0
0
0
172
7.5
36.5
15.5
119.4
286.8
1
0
1
1
1
0
1
0.87
1
146.1
96.2
128.7
91
49.9
112.8
1
1
1
ARB
0
0
1
0.5
0.5
3.34
Low
0
18.03
0
0
0
0
0
0.921
0
0.15
31.8
0.0133
14.6
40.3
1
5.13
19.03
6.57
12.25
487.3
102.7
27.8
0
32.5
39.3
231.2
3.767
1
1
5.7
0
0
1.25
15.5
0
3.6
1
12
0
27
Current
4
Western
43.8
Low
10
23.7
20
1,071
7.3
Lifestyle
DPP_standard
46.7
207
6.69
1
83.8
1
1
0
4
0
1
0
0
24,209
65.3
0.851
E88.81
2345-7
4548-4
8480-6
HC005-00000049
HC-END-005
60.1
Female
Hispanic
Medicare
2.6
1
1
0
Metabolically_Healthy
0
0
-0.194
2
0
22.1
62.2
167.8
80.7
1.1
34.9
50
466.4
4.58
20.4
0
232.9
140.9
52.5
197.7
39.5
180.4
93.4
12.3
36.4
3.77
89.9
1
0
0
null
0
0
0
0
0
97.5
5.1
14.8
3.56
149.7
147.4
0
0
0
0
0
0
0
1
1
130.4
80.8
110
68.8
49.7
97.3
1
1
1
ARB
1
0
0
0.5
0.5
2.08
Low
0
43.41
0
0
0
0
0
0.635
813
2.76
78.9
0.0166
17.8
49
1
5.97
19.67
5.07
1.63
213.6
71.2
6.3
0
8
8
29.7
1.701
0
0
5.8
0
0
3.17
20.2
0
0.5
0
4
0
1
Never
4
DASH
74
Moderate
177
32.9
14.7
16,000
7
Pharmacotherapy
null
49.3
338
10.08
0
83.5
0
0
0
6
0
0
1
0
10,061
57.9
0.922
R73.09
2345-7
4548-4
8480-6
HC005-00000050
HC-END-005
52.8
Male
Asian
Medicare
2.3
1
0
2
Established_MetS
1
1
1.054
4
6.3
32
93.2
170.8
98.8
1.13
34.3
83.7
345.2
7.32
42.4
1
217.5
113.6
52.3
257.9
51.6
165.1
82.8
13.6
50.1
4.93
117.2
1
0
1
Atorvastatin
40
0
0
0
0
290.3
8
7.8
5.59
12.3
348.5
1
0
1
0
0
0
1
1
1
132.3
97
112.1
85.3
35.3
108.8
1
1
1
CCB
0
0
0
0.5
0.5
1.07
Low
0
55.27
0
0
0
1
0
0.665
7
1.73
850.3
0.0032
13.8
43.6
1
5.5
11.78
5.24
9.28
179.6
74.4
7.6
0
20.2
13.8
40.8
1.628
1
0
6.2
0
0
1.74
12.9
1
10.8
1
14
0
16
Never
3
Mixed
38.4
Moderate
121
27.9
18.1
11,005
9.7
Lifestyle
DPP_standard
84.3
383
9.46
0
78.8
1
1
1
5
0
1
0
0
27,912
88.6
0.712
E88.81
2345-7
4548-4
8480-6
HC005-00000051
HC-END-005
55.5
Female
Hispanic
Medicare
6.7
0
1
0
Metabolically_Healthy
0
0
-0.17
2
0
26.3
70.7
163.8
94.9
1.09
39
74.4
430.4
6.26
54.3
1
155.2
92.4
43.6
95.9
19.2
111.6
54.4
3.2
24.9
2.2
43.6
0
1
0
null
0
0
0
0
0
94.1
5.2
6.6
1.52
73.5
136.4
0
0
0
0
0
0
0
1
1
109.5
64.5
101.3
60.2
45
79.5
0
0
0
ARB
1
0
0
0.5
0.5
2.34
Low
0
31.9
0
0
0
0
0
0.695
22
2.08
52.6
0.0678
17
81.2
1
4.06
11.71
3.83
9.88
223.5
105.5
35.7
1
35
28
10
2.628
1
0
7.1
1
0
3.35
21.6
1
18.9
0
2
0
38
Current
6
Mediterranean
89.3
Moderate
121
30.5
14.5
12,622
6.9
Control
null
50.5
473
4.83
0
82.5
0
0
0
3
0
0
0
0
16,289
89.2
1
R73.09
2345-7
4548-4
8480-6
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HC-END-005 — Metabolic Syndrome Synthetic Dataset (Sample)

XpertSystems.ai · Synthetic Data Factory · Endocrinology Vertical

A statistically sophisticated synthetic cohort of metabolic-syndrome patients built on a Gaussian copula (MESA/NHANES-calibrated correlation matrix) so the five MetS components — waist, triglycerides, HDL, fasting glucose, and blood pressure — are jointly correlated rather than independently sampled. Covers MetS diagnosis (NCEP-ATP III & IDF), continuous severity (Gurka/Kaplan Z-score), 4-cluster staging, full lipid/glycemic/BP panels, CVD risk (PCE/SCORE2/Framingham), adipokines & inflammation, renal/hepatic markers, lifestyle, intervention arms (DPP-style), and outcomes. This repository contains a 500-row, single-seed sample. The full commercial product scales to 30,000+ patients with 15-year follow-up and CSV / Parquet / JSON delivery.


Validation

This sample passes XpertSystems Grade A+ validation (overall 10.000 / 10) with deterministic reproduction across all six canonical seeds [42, 7, 123, 2024, 99, 1].

Validation philosophy: structural identities over distribution-fit tests — including a copula-fidelity check (correlation magnitude between waist and triglycerides is preserved). This engine also passes its own built-in 9-benchmark suite (MetS prevalence, T2DM, HTN, NAFLD, mean TG/HDL/SBP, MetS resolution, MACE). MetS prevalence lands at 33%, right on the NHANES ~34% anchor.

Calibration anchors

Metric Sample value Target range Source
MetS prevalence (NCEP-ATP III) 33.0% 29–40% NHANES 2013-2020 (~34%)
T2DM prevalence 12.0% 9–20% MetS-enriched cohort
Hypertension prevalence 52.6% 46–60% MetS-enriched
NAFLD prevalence 24.6% 18–42% NAFLD epidemiology
Mean triglycerides 179.8 mg/dL 155–195 MESA / NHANES marginals
Mean HDL 48.8 mg/dL 44–58 MESA / NHANES marginals
Mean SBP 126.6 mmHg 122–142 MESA / NHANES marginals
MACE rate (follow-up) 9.4% 5–18% Pooled Cohort Equations
Lifestyle-arm MetS resolution 1yr 47.7% 30–65% DPP lifestyle proxy
Copula |corr(waist,TG)| 0.27 ≥0.20 Gaussian copula (MESA target ~0.42)
IDF ⊆ NCEP consistency 100% ≥0.99 Definition integrity
Component count in [0,5] 100% ≥1.0 Diagnostic integrity
eGFR in [14,128] 100% ≥1.0 Renal physiology bounds
Column count 151 ≥145 Schema completeness

Schema highlights by module (151 columns)

Demographics & SDOH. Age, sex, race/ethnicity, insurance, SES, food insecurity, urban flag.

MetS diagnosis. 4-cluster label (Healthy/Early/Established/Refractory), NCEP & IDF flags, continuous Z-score, component count, duration; the five criterion flags (waist/TG/HDL/FG/BP).

Adiposity. BMI, weight, height, waist, WHR, body-fat %, visceral & subcutaneous fat area, visceral-adiposity-index, lipid-accumulation product.

Lipids. TC/LDL/HDL/TG/VLDL/non-HDL/ApoB/Lp(a)/sdLDL/TG-HDL ratio/remnant cholesterol; statin (type, LDL reduction), fibrate, omega-3.

Glycemia. Fasting glucose, HbA1c, fasting insulin, HOMA-IR/B, OGTT 2hr; T2DM & prediabetes flags; metformin, GLP-1, SGLT2i, insulin; GLP-1/SGLT2 cardiometabolic relative risks.

Blood pressure. SBP/DBP, treated SBP/DBP, pulse pressure, MAP, hypertension flag, BP class, control flag, ABPM, nocturnal dipping.

CVD risk & events. ASCVD-10yr (PCE), SCORE2, Framingham, risk category; MACE flag & TTE, CAD/stroke/HF/AFib/PAD; carotid IMT, coronary calcium; hs-CRP, NT-proBNP, troponin.

Adipokines & inflammation. Adiponectin, leptin (+ resistance), IL-6, TNF-α, resistin, visfatin, omentin-1.

Renal/hepatic. eGFR, UACR, CKD; ALT/AST/GGT, FIB-4, NAFLD/NASH; uric acid, hyperuricemia.

Endocrine & comorbidities. Hypothyroidism, TSH, cortisol; OSA & AHI, depression (PHQ-9), anxiety, stress (PSS).

Lifestyle. Smoking, alcohol, diet pattern & quality, physical-activity level, exercise minutes, VO₂max, steps, sleep.

Intervention & outcomes. Arm (Control/Lifestyle/Pharma/Combined), lifestyle sub-arm, adherence, caloric deficit, 1-yr weight loss, MetS resolution (1/3/5-yr); utilization, cost, EQ-5D.

Coding. ICD-10 (E88.81 MetS), LOINC.


Files

  • hc_end_005_sample.csv — 500-patient sample (151 columns)
  • generate_sample_dataset_hc_end_005.py — reproducible generator + validation harness
  • validation_report.json / validation_report.md — full scorecard
  • sweep_summary.json — 6-seed determinism results

Loading

import pandas as pd
df = pd.read_csv("hc_end_005_sample.csv")
print(df[["patient_id","mets_cluster_label","mets_z_score",
          "homa_ir","ascvd_10yr_risk_pct","intervention_type"]].head())
from datasets import load_dataset
ds = load_dataset("csv", data_files="hc_end_005_sample.csv")

Use cases

  • Metabolic-syndrome classification & severity (Z-score) modeling
  • Multi-component correlated-risk-factor analysis (copula-generated joint structure)
  • CVD-risk prediction and PCE/SCORE2 tooling
  • Intervention cost-effectiveness & DPP-style resolution modeling
  • Insulin-resistance / adipokine research prototyping
  • ML training where real cardiometabolic EHR data is PHI-restricted

Honest limitations & disclosed generator behavior

Transparency is a core XpertSystems principle. The v1.0 engine has the following known behaviors. They are reproducible and disclosed.

  1. Copula correlations are attenuated in Pearson space. The Gaussian copula sets the rank correlation of the five components, but subsequent marginal transforms and added independent noise (e.g. extra normal terms on glucose and SBP) dilute the final Pearson correlations — observed waist-TG ~0.27–0.39 vs the MESA target 0.42, and weaker still for glucose/SBP. The joint structure is real and far better than independent sampling, but is softer than the input matrix.
  2. TG-HDL correlation sign is positive. Due to a double-negative in the HDL transform (hdl = mu - sd·norm_ppf(U[:,2]) where U[:,2] already carries the negative copula loading), the realized triglyceride-HDL correlation is positive (0.28) rather than the expected negative (-0.45). Treat HDL's joint coupling with caution.
  3. visceral_adiposity_index is a proxy, not true VAI. The assembled field is visfatin·0.1 + bmi·0.2; the properly-computed VAI (sex-specific TG/waist formula) is calculated internally but discarded. Use lip_accum_product for a validated adiposity index.
  4. T2DM flag is HbA1c-derived. t2dm_flag = HbA1c ≥ 6.5 overrides the latent T2DM prior used to seed glucose, so the flag is internally consistent with HbA1c but can diverge from the fasting-glucose mixture in edge cases.

General caveat: cross-field correlations beyond those in the copula and explicit couplings may be weaker than in real cohorts. Not for clinical decision-making — research/development use only.


Commercial product comparison

Capability This sample Full HC-END-005 product
Patients 500 30,000+ (configurable)
Follow-up baseline + flags 15-year longitudinal
Seeds / cohorts 1 Multi-seed, reproducible
Formats CSV CSV + Parquet + JSON
Copula fidelity Attenuated (disclosed) Calibrated to recover target Pearson matrix
HDL coupling Positive sign (disclosed) Sign-corrected negative coupling
VAI Proxy (disclosed) Validated sex-specific VAI
License CC-BY-NC-4.0 Commercial
Support & SLA Included

Full product, custom cohorts, or other endocrinology SKUs: pradeep@xpertsystems.ai


Citation

@dataset{xpertsystems_hc_end_005_2026,
  title        = {HC-END-005: Metabolic Syndrome Synthetic Dataset},
  author       = {XpertSystems.ai},
  year         = {2026},
  publisher    = {XpertSystems.ai Synthetic Data Factory},
  url          = {https://xpertsystems.ai},
  note         = {Synthetic; CC-BY-NC-4.0 (sample). Gaussian-copula component structure
                  calibrated to: NHANES 2013-2020 MetS prevalence; MESA correlation
                  matrices (Multi-Ethnic Study of Atherosclerosis); CARDIA cluster
                  transitions; Diabetes Prevention Program (DPP) lifestyle/metformin arms;
                  LEADER (Marso 2016) and EMPA-REG OUTCOME (Zinman 2015); ACC/AHA Pooled
                  Cohort Equations; SPRINT and ACCORD-BP blood-pressure trials.}
}

Synthetic data generated by XpertSystems.ai. Not derived from real patient records. Not for clinical use.

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