AI & ML interests

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bartowski 
posted an update 5 months ago
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You may have noticed that my upload of MiMo-V2.5 upload didn't have the author in the model name:

bartowski/MiMo-V2.5-GGUF

Going forward, I plan to upload models from major 1st party developers without the author name attached for cleanliness, I feel it results in a nicer and more expected user experience

I will continue to uploaded fine tunes with that author + "_" appended for clarity, I personally feel it's nice to know at a glance who's tune it is, but it's also for the reason I first started doing it, to avoid it being confused for a new version of the official release

I hope this change makes sense, it seemed most reasonable to me and a poll I did (forever ago, I move slow sometimes) made it seem likely others would find it reasonable as well (feel free to let me know if you disagree, may not change my mind but I do value knowing what others think)

Thanks for downloading :)
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MaziyarPanahi 
posted an update 6 months ago
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Training mRNA Language Models Across 25 Species for $165

We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.

https://huggingface.co/blog/OpenMed/training-mrna-models-25-species
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MaziyarPanahi 
posted an update 6 months ago
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We annotated 119K medical images with two frontier VLMs (Qwen 3.5, Kimi K2.5), cross-validated at 93% agreement, and produced 110K training records, all for under $500. Fine-tuning 3 small models (2-3B params) improved all benchmarks: best model reaches +15.0% average exact match.

Everything is open-sourced: datasets, adapters, and code.

https://huggingface.co/blog/OpenMed/synthvision
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MaziyarPanahi 
posted an update 7 months ago
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DNA, mRNA, proteins, AI. I spent the last year going deep into computational biology as an ML engineer. This is Part I of what I found. 🧬

In 2024, AlphaFold won the Nobel Prize in Chemistry.

By 2026, the open-source community had built alternatives that outperform it.

That's the story I find most interesting about protein AI right now. Not just the science (which is incredible), but the speed at which open-source caught up. Multiple teams, independently, reproduced and then exceeded AlphaFold 3's accuracy with permissive licenses. The field went from prediction to generation: we're not just modeling known proteins anymore, we're designing new ones.

I spent months mapping this landscape for ML engineers. What the architectures actually are (spoiler: transformers and diffusion models), which tools to use for what, and which ones you can actually ship commercially.

New post on the Hugging Face blog: https://huggingface.co/blog/MaziyarPanahi/protein-ai-landscape

Hope you all enjoy! 🤗
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