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He had participated in and organized outdoor religious meetings set among areas of striking natural and geological beauty in New York, most notably the 1878 Watkins Glen Freethinkers Convention.
Intrigued by the Chatata site, he funded excavations there.
A high three-ply sandstone wall was unearthed with markings located on one surface of the middle layer.
Rawson believed these markings to be Hebrew and claimed to have translated several chapters of the Old Testament from them, evidence to him that one or more of the Ten Lost Tribes of Israel had arrived in Tennessee before Europeans or possibly even the Cherokee.
Subsequent visits to the site by other scientists, and samples from the Wall displayed for a time at the Smithsonian Institution, failed to generate support for Rawson's claims.
The Chatata Wall faded from the public limelight, and today its exact location is effectively unknown.
Eventually, the Chatata Wall was ultimately judged to be a natural phenomenon.
Whether its strange markings were of human, geological or paleontological origin is still a matter of debate.
London Buses route SL7, formerly London Buses route X26, is a Transport for London contracted Superloop express bus route in London, England.
Running between Heathrow Central bus station and West Croydon bus station, it is operated by London General.
History.
Route X26 has its origins in Green Line Coaches route 725, which started in the 1950s and ran from Gravesend and Dartford through Sidcup, Bromley, Croydon, Sutton and Kingston to Staines and Windsor.
In the late 1970s route 726 was introduced as a variant, from Gravesend to Windsor via Heathrow Airport and Slough instead of Staines.
By the 1980s, the sections of route between Heathrow and Windsor and between Gravesend and Dartford had been withdrawn.
At that time the Green Line network was operated by London Country Bus Services, but when that company was broken up in 1986 route 726, which ran almost entirely within Greater London, came under the control of London Country North West (LCNW) and Kentish Bus & Coach.
In 1991 LCNW planned to withdraw the route, but London Regional Transport stepped in and took the route over.
LCNW continued to operate the route on a short term one-year contract.
On 29 February 1992, London Coaches, a subsidiary of London Buses privatised in 1992, commenced operating the route using dual-purpose DAF SB220 vehicles.
The contract changed from London Coaches to Capital Logistics in the late 1990s, and passenger numbers continued to decline.
In 1997, London Transport attempted to withdraw the service, but at the end of year it was given an 18-month reprieve after over 1,600 letters had been received in its support.
Early in 1999 the service was cut back to run between Bromley and Heathrow only; the service became hourly, with no early morning or late evening service.
Capital Logistics was bought by Tellings-Golden Miller on 1 June 1999, shortly after a new contract for the 726 had been awarded.
New low-floor buses were specified, and seven Alexander ALX300 bodied Volvo B10BLEs were purchased.
In April 2005 route 726 was renumbered X26 and the section between Bromley and East Croydon was withdrawn, rerouted to run via Teddington instead of Hampton Court, and many stops were removed to reduce run times and improve reliability.
The contract was awarded to Metrobus, which used Scania OmniCity vehicles.
London Buses hoped that the re-modelled route would attract more passengers and therefore specified large single-deck buses.
It was initially intended to remove stops at Carshalton, Cheam, North Cheam and Worcester Park, but these were retained.
The peak vehicle requirement (PVR) fell from six buses to four.
On 22 November 2008, route X26 was doubled in frequency to every 30 minutes for most of the day, including Sundays, although the evening service remained hourly.
To cover for the increase in PVR while new vehicles were prepared, Metrobus hired Mercedes-Benz O530s from Wealden PSV, delivered directly from original owner Quality Line.
The Citaros were returned to Wealden PSV and replaced with Scania OmniCitys from the Crawley Fastway network, refurbished and painted red; these were two years older than the OmniCitys that previously worked on the route.
In June 2010, a proposal to reintroduce the former 726 stop at Beddington was rejected by Transport for London, despite support from many residents.
Upon being re-tendered, on 14 April 2012 the route passed to Quality Line with new Mercedes-Benz O530s.
When next tendered, it passed to London General on 15 April 2017.
Double deck Wright Eclipse Gemini 2 bodied Volvo B9TL buses that formerly operated East London Transit services were introduced after having their rear doors removed and additional luggage racks fitted.
On 19 August 2023, route X26 was renumbered SL7, becoming part of the Superloop network of orbital express bus routes with frequencies increased to every 8-20 minutes.
Current route.
Route SL7 operates via these primary locations: It is currently the longest bus route in London with a distance of 23.75 miles.
John Icha Lal (born Suva, Fiji 24 February 1933) was formerly a player, captain and coach of the Fiji national football team.
He was coach of the Fiji national football team from 1977 to 1978.
The sack of Aquileia occurred in 452, and was carried out by the Huns under the leadership of Attila.
Campaign.
A year after the Battle of Catalaunian Fields, Attila launched an invasion of Italy, passing through Pannonia into Venetia, where he laid siege to Aquileia.
Jordanes states that the city was well defended, to the point where Attila considered withdrawing.
Indeed, Ian Hughes suggests that since Aetius was unable to blockade the Julian Alps, he instead reinforced the city garrison to force Attila into a siege, or otherwise risk Roman forces cutting off his potential retreat.
The siege lasted for some time, and Jordanes states that as Attila was considering withdrawing, the city fell in a renewed assault and he razed it to the ground.
Before its destruction, Aquileia was a center of government (with an imperial residence), commerce and finance (with a mint), military defense, and Christianity (with a bishop).
Its destruction and Attila's subsequent unimpeded ravaging of the province of Venetia (modern Veneto and Friuli) paved the way for the rise of Venice, which within a few centuries replaced and even surpassed it in importance.
Aftermath.
Attila then proceeded to raid Italy, with Aetius able to do little more than harass Attila at best.
It was only when an embassy including Pope Leo I arrived that Attila finally ended his invasion, likely as a result of famine, disease, and an Eastern Roman Army approaching the Hunnic settlements near the Tisza.
Popular culture.
This sack appears as part of the final scenario in the Attila the Hun campaign in the Microsoft computer game "".
The destruction of Aquileia also figures prominently into the background of several characters in the novel "The Last Legion".
Kickers, Inc. is a twelve-issue comic book series published by Marvel Comics from 1986 to 1987 as part of the New Universe imprint.
Created by Tom DeFalco and Ron Frenz, the series featured a group of former professional American football players for the fictional New York Smashers team who became a group of heroes for hire, calling themselves "Kickers Inc."
They were led by Jack Magniconte, a Smashers player who gained super-human strength and endurance from a combination of exposure to radiation from the "White Event" and an experimental muscle-enhancing device.
Publication history.
Tom DeFalco and Ron Frenz created the series, then titled "Mr. Magnificent and his Team Supreme", for the New Universe line before the concept of the New Universe itself had been fleshed out.
Frenz explained: DeFalco and Frenz modified the series according to the New Universe premise, but "Kickers, Inc." still did not fit well within the New Universe's stated editorial goal of being more grounded in realism than the regular Marvel Comics Universe, its stories, characters and concepts being recognizably bas...
The series also suffered from creative instability to an even greater extent than the rest of the 1986-87 New Universe lineup, with nearly every issue being produced by a different creative team.
DeFalco himself lost interest early on; half of issue #3 and all of issues #4 and 5 were scripted by guest writers over DeFalco's plots, and by issue #6 neither he nor Frenz were involved with "Kickers, Inc." at all.
It was canceled with issue #12, along with other New Universe comics such as "Nightmask" and "Merc", though Jack Magniconte continued to make occasional appearances in the remaining New Universe titles.
Tom DeFalco and Ron Frenz had previously teamed up on "The Amazing Spider-Man" and would later work together on "Thor" as well as DeFalco's MC2 titles.
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells and participate in forming ribonucleoprotein complexes.
RBPs contain various structural motifs, such as RNA recognition motif (RRM), dsRNA binding domain, zinc finger and others.
They are cytoplasmic and nuclear proteins.
However, since most mature RNA is exported from the nucleus relatively quickly, most RBPs in the nucleus exist as complexes of protein and pre-mRNA called heterogeneous ribonucleoprotein particles (hnRNPs).
RBPs have crucial roles in various cellular processes such as: cellular function, transport and localization.
They especially play a major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation.
Eukaryotic cells express diverse RBPs with unique RNA-binding activity and protein–protein interaction.
According to the Eukaryotic RBP Database (EuRBPDB), there are 2961 genes encoding RBPs in humans.
During evolution, the diversity of RBPs greatly increased with the increase in the number of introns.
Diversity enabled eukaryotic cells to utilize RNA exons in various arrangements, giving rise to a unique RNP (ribonucleoprotein) for each RNA.
Although RBPs have a crucial role in post-transcriptional regulation in gene expression, relatively few RBPs have been studied systematically.It has now become clear that RNA–RBP interactions play important roles in many biological processes among organisms.
Structure.
Many RBPs have modular structures and are composed of multiple repeats of just a few specific basic domains that often have limited sequences.
Different RBPs contain these sequences arranged in varying combinations.
A specific protein's recognition of a specific RNA has evolved through the rearrangement of these few basic domains.
Each basic domain recognizes RNA, but many of these proteins require multiple copies of one of the many common domains to function.
Diversity.
As nuclear RNA emerges from RNA polymerase, RNA transcripts are immediately covered with RNA-binding proteins that regulate every aspect of RNA metabolism and function including RNA biogenesis, maturation, transport, cellular localization and stability.
All RBPs bind RNA, however they do so with different RNA-sequence specificities and affinities, which allows the RBPs to be as diverse as their targets and functions.
These targets include mRNA, which codes for proteins, as well as a number of functional non-coding RNAs.
NcRNAs almost always function as ribonucleoprotein complexes and not as naked RNAs.
These non-coding RNAs include microRNAs, small interfering RNAs (siRNA), as well as spliceosomal small nuclear RNAs (snRNA).
Function.
RNA processing and modification.
Alternative splicing.
Alternative splicing is a mechanism by which different forms of mature mRNAs (messengers RNAs) are generated from the same gene.
It is a regulatory mechanism by which variations in the incorporation of the exons into mRNA leads to the production of more than one related protein, thus expanding possible genomic outputs.
RBPs function extensively in the regulation of this process.
Some binding proteins such as neuronal specific RNA-binding proteins, namely NOVA1, control the alternative splicing of a subset of hnRNA by recognizing and binding to a specific sequence in the RNA (YCAY where Y indicates pyrimidine, U or C).
These proteins then recruit splicesomal proteins to this target site.
SR proteins are also well known for their role in alternative splicing through the recruitment of snRNPs that form the splicesome, namely U1 snRNP and U2AF snRNP.
However, RBPs are also part of the splicesome itself.
The splicesome is a complex of snRNA and protein subunits and acts as the mechanical agent that removes introns and ligates the flanking exons.
Other than core splicesome complex, RBPs also bind to the sites of "Cis"-acting RNA elements that influence exons inclusion or exclusion during splicing.
These sites are referred to as exonic splicing enhancers (ESEs), exonic splicing silencers (ESSs), intronic splicing enhancers (ISEs) and intronic splicing silencers (ISSs) and depending on their location of binding, RBPs work as splicing silencers or enhancers.
RNA editing.