entry stringlengths 6 10 | cc_function stringlengths 75 10.3k | question stringlengths 58 156 |
|---|---|---|
A0A1C3NSL9 | FUNCTION: Controls adherens junction integrity (PubMed:11715019). Required for the correct rate and completion of elongation of the embryos (PubMed:11715019). {ECO:0000269|PubMed:11715019}. | I would like a protein that controls adherens junction integrity and is required for correct embryonic elongation. |
A0A1C7D1B7 | FUNCTION: tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:27455459). The proposed mechanism is the following: (i) recruits S-adenosyl-L-methionine and cleaves it to generate a 5'-deoxyadenosine radical (5'-dA) in the radical S-adeno... | I need a protein that is a radical SAM-dependent enzyme modifying the wobble uridine of tRNA to carboxymethyluridine. |
A0A1C8AX29 | FUNCTION: Fatty acid synthase subunit beta; part of the gene cluster that mediates the biosynthesis of azaphilone pigments (MonAzPs), a complex mixture of compounds with a common azaphilone skeleton very widely used as food colorants (PubMed:26946170, PubMed:28959415, PubMed:34220766). PigJ and pigK form the two subuni... | Find me a protein that is the beta subunit of a fungal fatty acid synthase producing beta-keto fatty acids for azaphilone food colorant biosynthesis. |
A0A1D1VU85 | FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. {ECO:0000255|RuleBase:RU000393}. | I am looking for a protein that destroys toxic radical species produced within cells. |
A0A1D5AG16 | FUNCTION: Fatty acid synthase alpha subunit; part of the gene cluster that mediates the biosynthesis of azaphilone pigments (MonAzPs), a complex mixture of compounds with a common azaphilone skeleton very widely used as food colorants (PubMed:26946170, PubMed:28959415, PubMed:34220766). PigJ and pigK form the two subun... | Give me a protein that is the alpha subunit of a dedicated fungal fatty acid synthase synthesizing the side chain of azaphilone pigments. |
A0A1D5NS60 | FUNCTION: Probable transcription factor (Probable). Important for development and migration of oligodendrocyte precursor cells, and normal myelination of axons in the central nervous system (CNS) (PubMed:26459222). Functions autonomously in oligodendrocytes to promote CNS myelination (PubMed:26459222). Seems to act in ... | I want a protein that is a transcription factor promoting oligodendrocyte precursor development and central nervous system myelination. |
A0A1D5NSK0 | FUNCTION: Plays an essential role for patterning the left-right axis. Requires solely on the left side, downstream of the leftward flow, but upstream of dand5, a nodal inhibitor involved in left-right patterning. {ECO:0000269|PubMed:34903892}. | Design a protein that acts downstream of leftward nodal flow to establish the left-right body axis during embryogenesis. |
A0A1D5NSM8 | FUNCTION: Required for embryonic lymphatic vascular development, via promotion of parachordal lymphangioblast development, cell alignment and migration both dorsally and ventrally (PubMed:28179430, PubMed:28179432, PubMed:37097004). Required for the formation of facial lymphatic structures and formation of brain lympha... | Suggest a protein that is required for embryonic lymphatic vessel formation including parachordal lymphangioblast migration. |
A0A1D5NY17 | FUNCTION: Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (PubMed:34427057). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (PubMed:34427057). {ECO:0000269|PubMed:34427057}. | Generate a protein that negatively regulates skeletal muscle regeneration by suppressing integrin beta-1 activation and LAMB1 binding. |
A0A1D5PPP7 | FUNCTION: Cysteine protease that plays essential roles in programmed cell death, development and innate immunity (PubMed:11953316). Acts as a non-canonical executioner caspase during apoptosis: localizes in the nucleus and cleaves the nuclear structural protein lamin-A/LMNA thereby inducing nuclear shrinkage and fragme... | Provide a protein that is a caspase cleaving nuclear lamin-A during apoptosis and mediating inflammatory PANoptosis. |
A0A1D5PRR9 | FUNCTION: DNA-dependent ATPase component of the Fanconi anemia (FA) core complex (By similarity). Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal break... | I would like a protein that is a DNA-dependent ATPase in the Fanconi anemia complex required for interstrand crosslink repair. |
A0A1D5PUP4 | FUNCTION: Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B) (By similarity). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Acts as a Wnt7-speci... | I need a protein that enables Wnt7-specific signaling in brain endothelial cells for CNS angiogenesis and blood-brain barrier maintenance. |
A0A1D5PXA5 | FUNCTION: Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:11081638, PubMed:19864432). Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification (PubMed:11081638). Also activated by phorbol esters (PubMed:19864432)... | Find me a protein that is a calcium-permeant cation channel activated by hypotonicity and mechanical stimuli for osmosensing. |
A0A1D6E0S8 | FUNCTION: [Isoform 1]: Kinase that contributes to activation of the hypersensitive response, a form of programmed cell death, upon fungal infection. {ECO:0000269|PubMed:36577386}.; FUNCTION: [Isoform 2]: Secreted protein that contributes to activation of the hypersensitive response, a form of programmed cell death, upo... | I am looking for a protein that activates the plant hypersensitive response to fungal infection as part of a cell death defense. |
A0A1D6EFT8 | FUNCTION: Component of the volatile terpenes biosynthesis pathways (PubMed:30187155). Dihydroxylated sesquiterpenoid synthase that generates dually hydroxylated products directly from (E,E)-farnesyl diphosphate, primarily eudesmane-2,11-diol, along with two closely related structural isomers (PubMed:29570233). {ECO:000... | Give me a protein that is a sesquiterpene synthase directly producing dihydroxylated eudesmane products from farnesyl diphosphate. |
A0A1D6HSP4 | FUNCTION: Involved in the biosynthesis of homoterpenes, attractants of herbivores parasitoids and predators (e.g. predatory mites and parasitoid wasps) (By similarity). Component of the volatile terpenes biosynthesis pathways (PubMed:30187155). Converts mainly nerolidol to dimethylnonatriene (DMNT) and, to a lower exte... | I want a protein that converts nerolidol to DMNT to attract herbivore predators and parasitoids as a plant indirect defense volatile. |
A0A1D6K6U5 | FUNCTION: Involved in gibberellin biosynthesis (PubMed:16307364). Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate (ent-CPP) (PubMed:16307364). Involved in the production of antifungal dolabralexin phytoalexins in response to biotic and abiotic stresses (PubMed... | Design a protein that converts geranylgeranyl diphosphate to ent-copalyl diphosphate for gibberellin and antifungal phytoalexin biosynthesis. |
A0A1D6L709 | FUNCTION: Involved in the regulation of meristem development and seed maturation processes. Mediates regulation of embryonic regulatory genes and genes controlling abscisic acid (ABA) biosynthesis and turnover in developing seeds. May be required for the synthesis of small signaling molecules that integrates meristem a... | Suggest a protein that regulates meristem development and abscisic acid biosynthesis genes during seed maturation. |
A0A1D6LAB7 | FUNCTION: Nuclear genome-encoded factor involved in ribosome biogenesis in chloroplasts. Binds specific group II introns in chloroplasts and facilitates their splicing. Is required for rRNA maturation in plastids and may contribute to the assembly of the large (50S) ribosomal subunit. Required for normal development of... | Generate a protein that binds group II introns in chloroplasts to facilitate their splicing and support plastid ribosome biogenesis. |
A0A1D6LTV0 | FUNCTION: Component of the volatile terpenes biosynthesis pathways (PubMed:30187155). Mediates the synthesis of a blend of monoterpenes. Converts mainly geranyl diphosphate to alpha-terpineol. Also triggers the biosynthesis of minor monoterpenes including limonene, gamma-terpinene, beta-myrcene, terpinolene and 4-terpi... | Provide a protein that is a monoterpene synthase converting geranyl diphosphate primarily to alpha-terpineol with multiple minor products. |
A0A1D8EJF9 | FUNCTION: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiatio... | I would like a protein that recognizes the mRNA 5' cap and recruits mRNAs to ribosomes, also acting as a potyvirus susceptibility factor. |
A0A1D8PCL1 | FUNCTION: High-affinity glucose transporter (PubMed:10612724, PubMed:12187386). Acts as a multifunctional complement-evasion molecule that causes down-regulation of complement activation by acquisition of human complement factors FH and C4BP (PubMed:21844307). Also functions as a human immunodeficiency virus (HIV) rece... | I need a protein that is a high-affinity glucose transporter that also evades host complement by binding Factor H and C4BP. |
A0A1D8PDV7 | FUNCTION: Multifunctional phosphatidylinositol 3-kinase involved in acidification of vacuoles, pH-dependent cell growth, and autophagocytosis (PubMed:15632428, PubMed:15861817). Plays an important role in protein transport and virulence (PubMed:11223944, PubMed:15632428). Component of the autophagy-specific VPS34 PI3-k... | Find me a protein that is a PI3-kinase essential for vacuole acidification, autophagy, and protein trafficking in a fungal pathogen. |
A0A1D8PFP2 | FUNCTION: Transcription factor that mediates conventional biofilm formation and plays a key role in microcolony formation under both flow and static conditions and to epithelial surfaces (PubMed:22265407, PubMed:23637598, PubMed:28793308, PubMed:30252918, PubMed:36847358). Modulates infection of mammalian hosts (PubMed... | I am looking for a protein that is a transcription factor driving fungal biofilm and microcolony formation for host infection. |
A0A1D8PHA3 | FUNCTION: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation (PubMed:34525326, PubMed:36923588). The complex plays an important role in the uptake of multiple carbon sources presen... | Give me a protein that is a subunit of the mitochondrial ubiquinol-cytochrome c oxidoreductase driving oxidative phosphorylation. |
A0A1D8PI22 | FUNCTION: FAD-dependent oxidoreductase involved in the regulation of cell death (PubMed:27121326). In addition to the classical caspase-dependent apoptosis, cells can undergo caspase-independent apoptosis by releasing AIF1, which translocates to the nucleus for disrupting the nuclear chromatin (Probable). Plays an impo... | I want a protein that is a FAD-dependent oxidoreductase regulating caspase-independent apoptosis and protecting against oxidative stress. |
A0A1D8PJ01 | FUNCTION: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (PubMed:19432523, PubMed:23374681, PubMed:31143168, P... | Design a protein that is a plasma membrane H+-ATPase generating proton gradients to drive nutrient uptake and hyphal growth. |
A0A1D8PJ72 | FUNCTION: Transcription factor functions primary as a transcriptional repressor to maintain vacuole homeostasis when the fungus faces fluctuations in nitrogen (PubMed:34781731). Binds the 5'-TAAATCCG-3' consensus sequence upstream of genes encoding vacuolar and intracellular vesicle trafficking components (PubMed:34781... | Suggest a protein that is a transcriptional repressor maintaining vacuole homeostasis and regulating fungal filamentation during host infection. |
A0A1D8PJA8 | FUNCTION: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling (By similarity). Plays a role in engulfment by host macrophages (PubMed:26087349). {ECO:0000250|UniProtKB:P38288, ECO:0000269|PubMed:26087349... | Generate a protein that is a beta-1,3-glucanase remodeling the fungal cell wall to modulate macrophage engulfment. |
A0A1D8PJX3 | FUNCTION: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation (PubMed:34525326, PubMed:36923588). The complex plays an important role in the uptake of multiple carbon sources presen... | Provide a protein that is a mitochondrial complex III subunit essential for respiration and multi-carbon source utilization. |
A0A1D8PKB4 | FUNCTION: Serine/threonine protein kinase required to cause normal damage to epithelial cells and resist antimicrobial peptides. {ECO:0000269|PubMed:19700637}. | I would like a protein that is a serine/threonine kinase required for host epithelial cell damage and antimicrobial peptide resistance. |
A0A1D8PN96 | FUNCTION: Transcriptional activator of drug-responsive genes including the ABC-type transporters CDR1 and CDR2, as well as HSP12 and RTA3 (PubMed:15590837, PubMed:17905926, PubMed:19561319, PubMed:30104273). Binds the cis-acting regulatory drug-responsive elements (DREs) with the consensus sequence 5'-CGGAWATCGGATATTTT... | I need a protein that is a transcription factor activating ABC-type drug transporter genes in response to antifungal drug exposure. |
A0A1D8PNM8 | FUNCTION: Transcription factor required for full virulence in mice (PubMed:22073120, PubMed:25999923). Involved in metabolism, including utilization of the pentose sugar D-ribose which is required for driving lethal synergism during Staphylococcus aureus co-infection (PubMed:38982056). Regulates genes such as RBK1 and ... | Find me a protein that is a transcription factor governing ribose catabolism genes for enhanced virulence during fungal-bacterial co-infection. |
A0A1D8PNR5 | FUNCTION: Spermidine transporter that is also used by salivary gland-secreted histatin 5 (Hst 5) to enter into candidal cells (PubMed:22033918, PubMed:23613860, PubMed:24247141). A major component of host nonimmune defense systems is salivary histatins, a family of small (3-4 kDa), histidine-rich, cationic proteins sec... | I am looking for a protein that is a spermidine transporter that also enables uptake of the antifungal salivary peptide histatin 5. |
A0A1D8PPK1 | FUNCTION: Oxidoreductase that binds mammalian estrogens with high affinity. {ECO:0000250|UniProtKB:P43084}. | Give me a protein that is an oxidoreductase that binds mammalian estrogens with high affinity. |
A0A1D8PQ86 | FUNCTION: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections (PubMed:17510860, PubMed:22321066, PubMed:22429754). Allele ALS9-2 contributes to endothelial cell adhesion, whereas ALS9-1 does not (Pub... | I want a protein that is a cell surface adhesin mediating yeast attachment to host tissues and promoting fungal cell aggregation. |
A0A1D8PQB9 | FUNCTION: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. {ECO:0000269|PubMed:22321066, ECO:0000269|PubMed:22429754}. | Design a protein that is a fungal cell surface adhesin mediating attachment to host tissue and yeast aggregation. |
A0A1D8PRB7 | FUNCTION: Transcription factor required for full virulence (PubMed:22073120, PubMed:27932543). Needed to withstand host generated reactive oxygen species (ROS) and establish a sustained infection in vivo (PubMed:27932543). Acts as a master regulator of zinc cluster transcription factors (PubMed:27932543). Regulates gen... | Suggest a protein that is a master transcription regulator governing oxidative stress resistance, metal homeostasis, and multidrug efflux for virulence. |
A0A1D8PS71 | FUNCTION: Catalyzes the phosphate monoester hydrolysis of phytic acid (myo-inositol hexakisphosphate), which results in the stepwise formation of myo-inositol pentakis-, tetrakis-, tris-, bis-, and monophosphates, as well as the liberation of inorganic phosphate (PubMed:29216308). Myo-inositol 2-monophosphate is the en... | Generate a protein that is a phytase hydrolyzing phytic acid to release inorganic phosphate, contributing to tissue damage during infection. |
A0A1D8PSC7 | FUNCTION: Transcription factor required for wild-type filamentous growth which is important for the virulence. {ECO:0000269|PubMed:12773383, ECO:0000305|PubMed:19779551}. | Provide a protein that is a transcription factor required for filamentous growth and virulence in a fungal pathogen. |
A0A1D8PT03 | FUNCTION: Flavodoxin-like protein (FLP) that plays a role in cell wall integrity, oxidative stress protection and virulence (PubMed:26087349, PubMed:26325183). FLPs act as NAD(P)H quinone oxidoreductases (PubMed:26325183). Reduces ubiquinone (coenzyme Q), enabling it to serve as an antioxidant in the membrane (PubMed:2... | I would like a protein that is a flavodoxin-like NAD(P)H quinone oxidoreductase reducing ubiquinone to protect against oxidative stress. |
A0A1D8PTL7 | FUNCTION: Potassium transporter that mediates K(+) influx, as well as Cl(-) efflux as a secondary function (PubMed:15485849, PubMed:19175416, PubMed:33069635). TRK1 is the major K(+) uptake transporter that regulates membrane potential and intracellular pH (PubMed:33069635). The TRK1-mediated Cl(-) efflux should serve ... | I need a protein that is a major potassium uptake transporter that also mediates chloride efflux to regulate membrane potential and pH. |
A0A1D9BZF0 | FUNCTION: May play a role in DNA-protein cross-links (DPCs) clearance through a SUMO-dependent recruitment to sites of DPCs, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage (PubMed:31839538). Can resolve the topoisomerase II (TOP2A) DPCs (PubMed:31839538). {ECO:0... | Find me a protein that resolves DNA-protein crosslinks via SUMO-dependent recruitment to protect germline genomic integrity. |
A0A1E1FFL0 | FUNCTION: Multifunctional dioxygenase; part of the gene cluster that mediates the biosynthesis of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture (PubMed:27602587). The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide syn... | I am looking for a protein that is a multifunctional dioxygenase performing desaturation and ring rearrangement steps in meroterpenoid biosynthesis. |
A0A1E3P8S6 | FUNCTION: Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA. Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate. {ECO:0000269|PubMed:28356220}. | Give me a protein that synthesizes ethyl acetate from ethanol and acetyl-CoA and can also hydrolyze thioesters and esters. |
A0A1F4 | FUNCTION: Essential for the formation of matrix-filled interrhabdomeral space: critical for the formation of epithelial lumina in the retina. Acts together with prominin (prom) and the cell adhesion molecule chaoptin (chp) to choreograph the partitioning of rhabdomeres into an open system. {ECO:0000269|PubMed:17011488,... | I want a protein that organizes the interrhabdomeral space in the retina to partition rhabdomeres into an open system. |
A0A1I9LM04 | FUNCTION: Essential protein (PubMed:23929493). Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes (By similarity). The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisome... | Design a protein that is a condensin complex regulatory subunit required for mitotic chromosome condensation and meiotic chromosome compaction. |
A0A1I9LMX5 | FUNCTION: Extracellular signaling peptide that represses primary root growth rate and significantly inhibits lateral root formation. Modulates leaf morphology (PubMed:24179096). Regulates systemic nitrogen (N)-demand signaling. Mediates up-regulation of genes involved in N uptake and assimilation pathways (PubMed:25324... | Suggest a protein that is a secreted signaling peptide repressing root growth and mediating systemic nitrogen demand signaling. |
A0A1I9LN01 | FUNCTION: Required for phyA-controlled responses to continuous far-red light (FRc) conditions, including the inhibition of hypocotyl elongation and the regulation of XTH15/XTR7 expression. {ECO:0000269|PubMed:14645728}. | Generate a protein that is required for phytochrome A signaling to inhibit hypocotyl elongation under continuous far-red light. |
A0A1J1DL12 | FUNCTION: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism (PubMed:27539850). May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediat... | Provide a protein that hydrolyzes toxic enamine and imine metabolic intermediates to release ammonia as a metabolite damage-control enzyme. |
A0A1L3THR9 | FUNCTION: Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine polymers in chitin to form chitosan and acetate (PubMed:27901067). May play a role in evasion of the host immune response; plant chitinases liberate chitin molecules from the fungal cell wall which act as elicitors of the plant immune response, deace... | I would like a protein that deacetylates chitin to produce chitosan and evades plant immune recognition of fungal cell wall fragments. |
A0A1L4BJ46 | FUNCTION: Scorpion venom phospholipase A2 (PLA2) that shows high hydrolytic activities towards lecithin and acts as an effective blocker of all angiogenesis key steps in vivo and in vitro (PubMed:26335363). It has no effect on apoptosis and does not display hemolytic, inflammatory or neurotoxic effects (PubMed:26335363... | I need a protein that is a venom PLA2 that hydrolyzes phosphatidylcholine and blocks all key steps of angiogenesis without hemolytic effects. |
A0A1L4BJ98 | FUNCTION: Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity). This toxin acts on sphingomyelin (SM) with a high activity (PubMed:28335389). ... | Find me a protein that is a dermonecrotic toxin cleaving sphingomyelin via transphosphatidylation to cause skin necrosis and vascular permeability. |
A0A1L4BKS3 | FUNCTION: The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a sma... | I am looking for a protein that is a phage terminase large subunit acting as an ATP-driven motor to package viral DNA into capsids. |
A0A1L5YRA2 | FUNCTION: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. {ECO:0000250|UniProtKB:P00939}.; FUNCTION: It is also responsible for the non-negligible p... | Give me a protein that interconverts dihydroxyacetone phosphate and glyceraldehyde-3-phosphate in glycolysis and gluconeogenesis. |
A0A1L6K371 | FUNCTION: Seed storage protein. {ECO:0000255|RuleBase:RU003681, ECO:0000305|PubMed:27936684}. | I want a protein that functions as a seed storage protein. |
A0A1L6Z3A0 | FUNCTION: Converts geranylgeranyl diphosphate to an new 5,7-fused bicyclic diterpene, named pseudolaratriene (PubMed:28096378). Catalyzes the first committed step in pseudolaric acid B (PAB) biosynthesis (PubMed:28096378). PAB exhibits antiproliferative activity by inhibiting microtubule polymerization, and has demonst... | Design a protein that converts geranylgeranyl diphosphate to pseudolaratriene as the first step in antitumor pseudolaric acid B biosynthesis. |
A0A1L7NQ96 | FUNCTION: Catalyzes the reversible C-3 epimerization of several ketoses. Shows the highest enzymatic activity for the epimerization of L-ribulose to L-xylulose. Is also able to convert D-allulose (also known as D-psicose) to D-fructose and, to a lesser extent, L-tagatose to L-sorbose, D-ribulose to D-xylulose, L-allulo... | Suggest a protein that epimerizes ketoses at C-3 with highest activity toward L-ribulose and also converts D-allulose to D-fructose. |
A0A1L8F5J9 | FUNCTION: Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:16214956, PubMed:19524674). NMDARs participate in synaptic plasticity (By similarity). Channel activation req... | Generate a protein that is a GluN2 subunit of NMDA receptors forming calcium-permeable ion channels activated by glutamate and glycine. |
A0A1L8FDW4 | FUNCTION: Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) (PubMed:35931083). Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing throu... | Provide a protein that is a peroxin receptor binding PTS1-containing cargo proteins and translocating them into the peroxisome matrix. |
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