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|---|---|---|---|---|---|---|
note_49894_span_Pregnancy_1800000_1850000_mid_mesh | the coronavirus disease 2019 | The ultimate outcome of<think> (COVID-19) pandemic is unknown and is dependent on a complex interplay of its pathogenicity, transmissibility, and population immunity. In the current study, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was investigated for the presence of large-scale internal RNA base pa... | false | note_49894 | note_49894_ the coronavirus disease 2019 | 824,001 |
note_49894_span_Pregnancy_1800000_1850000_mid_mesh | prolonged infections and | The ultimate outcome of the coronavirus disease 2019 (COVID-19) pandemic is unknown and is dependent on a complex interplay of its pathogenicity, transmissibility, and population immunity. In the current study, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was investigated for the presence of large-scale... | true | note_49894 | note_49894_ prolonged infections and | 824,002 |
note_49895_span_Treatment Outcome_1800000_1850000_mid_mesh | on/off treatment cycles | OBJECTIVES: Non-cystic fibrosis bronchiectasis (NCFBE) with Pseudomonas aeruginosa has been associated with increased pulmonary exacerbation (PEx) and mortality risk. European Respiratory Society guidelines conditionally recommend inhaled antimicrobials for persons with NCFBE, P aeruginosa and three or more PEx/year. W... | false | note_49895 | note_49895_ on/off treatment cycles | 824,003 |
note_49895_span_Animals_1800000_1850000_mid_mesh | inhaled antimicrobials for | OBJECTIVES: Non-cystic fibrosis bronchiectasis (NCFBE) with Pseudomonas aeruginosa has been associated with increased pulmonary exacerbation (PEx) and mortality risk. European Respiratory Society guidelines conditionally recommend<think> persons with NCFBE, P aeruginosa and three or more PEx/year. We report microbiolo... | false | note_49895 | note_49895_ inhaled antimicrobials for | 824,004 |
note_49896_span_Male_1800000_1850000_mid_mesh | acute pulmonary embolism | PURPOSE: Little is known about the characteristics and impact of<think> (PE) during episodes of asthma exacerbation. We aimed to characterize patients diagnosed with acute PE in the setting of asthma exacerbation, develop a prediction model to help identify future patients and assess the impact of acute PE on hospital... | false | note_49896 | note_49896_ acute pulmonary embolism | 824,005 |
note_49896_span_Male_1800000_1850000_mid_mesh | of asthma exacerbation. | PURPOSE: Little is known about the characteristics and impact of acute pulmonary embolism (PE) during episodes<think> We aimed to characterize patients diagnosed with acute PE in the setting of asthma exacerbation, develop a prediction model to help identify future patients and assess the impact of acute PE on hospita... | true | note_49896 | note_49896_ of asthma exacerbation. | 824,006 |
note_49896_span_Male_1800000_1850000_mid_mesh | thrombosis, malignancy, | PURPOSE: Little is known about the characteristics and impact of acute pulmonary embolism (PE) during episodes of asthma exacerbation. We aimed to characterize patients diagnosed with acute PE in the setting of asthma exacerbation, develop a prediction model to help identify future patients and assess the impact of acu... | true | note_49896 | note_49896_ thrombosis, malignancy, | 824,007 |
note_49897_span_Mice_1800000_1850000_mid_mesh | (MEG)-MRI device | With a hybrid magnetoencephalography<think> that uses the same sensors for both modalities, the co-registration of MRI and MEG data can be replaced by an automatic calibration step. Based on the highly accurate signal model of ultra-low-field (ULF) MRI, we introduce a calibration method that eliminates the error sourc... | false | note_49897 | note_49897_ (MEG)-MRI device | 824,008 |
note_49897_span_Time Factors_1800000_1850000_mid_mesh | (MEG)-MRI device that uses | With a hybrid magnetoencephalography<think> the same sensors for both modalities, the co-registration of MRI and MEG data can be replaced by an automatic calibration step. Based on the highly accurate signal model of ultra-low-field (ULF) MRI, we introduce a calibration method that eliminates the error sources of trad... | false | note_49897 | note_49897_ (MEG)-MRI device that uses | 824,009 |
note_49897_span_Time Factors_1800000_1850000_mid_mesh | calibration step. Based | With a hybrid magnetoencephalography (MEG)-MRI device that uses the same sensors for both modalities, the co-registration of MRI and MEG data can be replaced by an automatic<think> on the highly accurate signal model of ultra-low-field (ULF) MRI, we introduce a calibration method that eliminates the error sources of t... | true | note_49897 | note_49897_ calibration step. Based | 824,010 |
note_49897_span_Time Factors_1800000_1850000_mid_mesh | low-SNR images, sub-voxel | With a hybrid magnetoencephalography (MEG)-MRI device that uses the same sensors for both modalities, the co-registration of MRI and MEG data can be replaced by an automatic calibration step. Based on the highly accurate signal model of ultra-low-field (ULF) MRI, we introduce a calibration method that eliminates the er... | true | note_49897 | note_49897_ low-SNR images, sub-voxel | 824,011 |
note_49897_span_Time Factors_1800000_1850000_mid_mesh | accurate sensor-array | With a hybrid magnetoencephalography (MEG)-MRI device that uses the same sensors for both modalities, the co-registration of MRI and MEG data can be replaced by an automatic calibration step. Based on the highly accurate signal model of ultra-low-field (ULF) MRI, we introduce a calibration method that eliminates the er... | true | note_49897 | note_49897_ accurate sensor-array | 824,012 |
note_49898_span_Risk Factors_1800000_1850000_mid_mesh | Background: Evidence suggests | <think> that the medical profession is reluctant to report mental ill-health despite its high prevalence.Aims: To compare differential reporting patterns in the incidence of work-related mental ill-health (WRMIH) affecting doctors with selected comparison occupational groups, as determined by surveillance by general pr... | false | note_49898 | note_49898_Background: Evidence suggests | 824,013 |
note_49898_span_Risk Factors_1800000_1850000_mid_mesh | 0.001).Conclusions: | Background: Evidence suggests that the medical profession is reluctant to report mental ill-health despite its high prevalence.Aims: To compare differential reporting patterns in the incidence of work-related mental ill-health (WRMIH) affecting doctors with selected comparison occupational groups, as determined by surv... | true | note_49898 | note_49898_ 0.001).Conclusions: | 824,014 |
note_49899_span_Mice_1800000_1850000_mid_mesh | INTRODUCTION: | <think> From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbionts pro... | false | note_49899 | note_49899_INTRODUCTION: | 824,015 |
note_49899_span_Mice_1800000_1850000_mid_mesh | the metabolomic | INTRODUCTION: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbion... | true | note_49899 | note_49899_ the metabolomic | 824,016 |
note_49899_span_Mice_1800000_1850000_mid_mesh | phylogeny.METHODS: | INTRODUCTION: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbion... | true | note_49899 | note_49899_ phylogeny.METHODS: | 824,017 |
note_49899_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | aim to characterize the | INTRODUCTION: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbion... | false | note_49899 | note_49899_ aim to characterize the | 824,018 |
note_49899_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | metabolomic diversity of | INTRODUCTION: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbion... | true | note_49899 | note_49899_ metabolomic diversity of | 824,019 |
note_49899_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | including climate change | INTRODUCTION: From shallow water to the deep sea, corals form the basis of diverse communities with significant ecological and economic value. These communities face many anthropogenic stressors including energy and mineral extraction activities, ocean acidification and rising sea temperatures. Corals and their symbion... | true | note_49899 | note_49899_ including climate change | 824,020 |
note_49900_span_Risk Factors_1800000_1850000_mid_mesh | recognized complication of | BACKGROUND: Aortic root thrombosis (ART) is a recently<think> continuous-flow left ventricular assist device (CF-LVAD) therapy. However, little is known about the prevalence or clinical significance of this complication. The aim of our study was to systematically evaluate the incidence and significance of ART on CF-LV... | true | note_49900 | note_49900_ recognized complication of | 824,021 |
note_49900_span_Risk Factors_1800000_1850000_mid_mesh | EPPY).CONCLUSIONS: | BACKGROUND: Aortic root thrombosis (ART) is a recently recognized complication of continuous-flow left ventricular assist device (CF-LVAD) therapy. However, little is known about the prevalence or clinical significance of this complication. The aim of our study was to systematically evaluate the incidence and significa... | true | note_49900 | note_49900_ EPPY).CONCLUSIONS: | 824,022 |
note_49901_span_Signal Transduction_1800000_1850000_mid_mesh | that G protein-coupled | Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of �1 adrenergic receptors (�ARs) on cardiac myocytes. Blocking these receptors is part of the basis for �-blocker therapy for heart failure. Recent data demonstrate<think> recepto... | false | note_49901 | note_49901_ that G protein-coupled | 824,023 |
note_49901_span_Signal Transduction_1800000_1850000_mid_mesh | receptors (GPCRs), | Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of �1 adrenergic receptors (�ARs) on cardiac myocytes. Blocking these receptors is part of the basis for �-blocker therapy for heart failure. Recent data demonstrate that G protein-... | true | note_49901 | note_49901_ receptors (GPCRs), | 824,024 |
note_49901_span_Signal Transduction_1800000_1850000_mid_mesh | a pathway activated by | Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of �1 adrenergic receptors (�ARs) on cardiac myocytes. Blocking these receptors is part of the basis for �-blocker therapy for heart failure. Recent data demonstrate that G protein-... | true | note_49901 | note_49901_ a pathway activated by | 824,025 |
note_49901_span_Aged_1800000_1850000_mid_mesh | heart failure, | Increased adrenergic tone resulting from cardiovascular stress leads to development of<think> in part, through chronic stimulation of �1 adrenergic receptors (�ARs) on cardiac myocytes. Blocking these receptors is part of the basis for �-blocker therapy for heart failure. Recent data demonstrate that G protein-coupled... | false | note_49901 | note_49901_ heart failure, | 824,026 |
note_49901_span_Aged_1800000_1850000_mid_mesh | �-blocker therapies | Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of �1 adrenergic receptors (�ARs) on cardiac myocytes. Blocking these receptors is part of the basis for �-blocker therapy for heart failure. Recent data demonstrate that G protein-... | true | note_49901 | note_49901_ �-blocker therapies | 824,027 |
note_49902_span_Pregnancy_1800000_1850000_mid_mesh | identify patients who | OBJECTIVE: To compare the accuracy of a whiplash-specific risk screening tool (WhipPredict) with that of the modified generic short-form ?rebro Musculoskeletal Pain Screening Questionnaire (SF-?MPSQ) for predicting poor recovery in patients following whiplash injury.STUDY DESIGN: Inception cohort study.METHODS: Two hun... | true | note_49902 | note_49902_ identify patients who | 824,028 |
note_49902_span_Pregnancy_1800000_1850000_mid_mesh | fewer patients falsely | OBJECTIVE: To compare the accuracy of a whiplash-specific risk screening tool (WhipPredict) with that of the modified generic short-form ?rebro Musculoskeletal Pain Screening Questionnaire (SF-?MPSQ) for predicting poor recovery in patients following whiplash injury.STUDY DESIGN: Inception cohort study.METHODS: Two hun... | true | note_49902 | note_49902_ fewer patients falsely | 824,029 |
note_49903_span_Time Factors_1800000_1850000_mid_mesh | applied as soon as possible | In this work, we analyze the growth of the cumulative number of confirmed infected cases by a novel coronavirus (COVID-19) until March 27, 2020, from countries of Asia, Europe, North America, and South America. Our results show that (i) power-law growth is observed in all countries; (ii) by using the distance correlati... | false | note_49903 | note_49903_ applied as soon as possible | 824,032 |
note_49903_span_Disease Models, Animal_1800000_1850000_mid_mesh | a model and | In this work, we analyze the growth of the cumulative number of confirmed infected cases by a novel coronavirus (COVID-19) until March 27, 2020, from countries of Asia, Europe, North America, and South America. Our results show that (i) power-law growth is observed in all countries; (ii) by using the distance correlati... | false | note_49903 | note_49903_ a model and | 824,033 |
note_49904_span_Prognosis_1800000_1850000_mid_mesh | patient outcomes.OBJECTIVES: | BACKGROUND: The teach-back method, also known as the "show-me" method, has been endorsed by many medical and health care societies. However, limited investigation has been conducted regarding its association with<think> To examine the association between patient teach-back experience and the risk of hospitalizations a... | false | note_49904 | note_49904_ patient outcomes.OBJECTIVES: | 824,034 |
note_49904_span_Signal Transduction_1800000_1850000_mid_mesh | information.CONCLUSIONS: | BACKGROUND: The teach-back method, also known as the "show-me" method, has been endorsed by many medical and health care societies. However, limited investigation has been conducted regarding its association with patient outcomes.OBJECTIVES: To examine the association between patient teach-back experience and the risk ... | false | note_49904 | note_49904_ information.CONCLUSIONS: | 824,035 |
note_49905_span_Male_1800000_1850000_mid_mesh | This study aims | The management of follow-up recommendations is fundamental for the appropriate care of patients with incidental pulmonary findings. The lack of communication of these important findings can result in important actionable information being lost in healthcare provider electronic documents.<think> to analyze follow-up re... | true | note_49905 | note_49905_ This study aims | 824,036 |
note_49905_span_Male_1800000_1850000_mid_mesh | different patient cohorts | The management of follow-up recommendations is fundamental for the appropriate care of patients with incidental pulmonary findings. The lack of communication of these important findings can result in important actionable information being lost in healthcare provider electronic documents. This study aims to analyze foll... | true | note_49905 | note_49905_ different patient cohorts | 824,037 |
note_49905_span_Male_1800000_1850000_mid_mesh | assessment. | The management of follow-up recommendations is fundamental for the appropriate care of patients with incidental pulmonary findings. The lack of communication of these important findings can result in important actionable information being lost in healthcare provider electronic documents. This study aims to analyze foll... | true | note_49905 | note_49905_ assessment. | 824,038 |
note_49905_span_Disease Models, Animal_1800000_1850000_mid_mesh | for oncology | The management of follow-up recommendations is fundamental for the appropriate care of patients with incidental pulmonary findings. The lack of communication of these important findings can result in important actionable information being lost in healthcare provider electronic documents. This study aims to analyze foll... | false | note_49905 | note_49905_ for oncology | 824,039 |
note_49906_span_Risk Factors_1800000_1850000_mid_mesh | a complication of | Unilateral bronchial occlusion,<think> many lung diseases, causes dyspnea but the mechanism of this symptom is uncertain. In this study, electromyographic (EMG) activity in the parasternal and external intercostal muscles in the third intercostal space and inspiratory motion of the third rib on both sides of the thora... | false | note_49906 | note_49906_ a complication of | 824,041 |
note_49906_span_Animals_1800000_1850000_mid_mesh | anesthetized dogs. | Unilateral bronchial occlusion, a complication of many lung diseases, causes dyspnea but the mechanism of this symptom is uncertain. In this study, electromyographic (EMG) activity in the parasternal and external intercostal muscles in the third intercostal space and inspiratory motion of the third rib on both sides of... | false | note_49906 | note_49906_ anesthetized dogs. | 824,042 |
note_49907_span_Aged_1800000_1850000_mid_mesh | a potential screening | BACKGROUND & AIMS: Early detection of hepatocellular carcinoma (HCC) before imaging signs appear remains an unmet medical need. Former publications suggest that soluble urokinase plasminogen activator receptor (suPAR) is a non-specific cancer marker. suPAR was validated for the detection of patients at risk for HCC.MET... | false | note_49907 | note_49907_ a potential screening | 824,043 |
note_49907_span_Male_1800000_1850000_mid_mesh | BACKGROUND & AIMS: | <think> Early detection of hepatocellular carcinoma (HCC) before imaging signs appear remains an unmet medical need. Former publications suggest that soluble urokinase plasminogen activator receptor (suPAR) is a non-specific cancer marker. suPAR was validated for the detection of patients at risk for HCC.METHODS: After... | false | note_49907 | note_49907_BACKGROUND & AIMS: | 824,044 |
note_49907_span_Male_1800000_1850000_mid_mesh | soluble urokinase | BACKGROUND & AIMS: Early detection of hepatocellular carcinoma (HCC) before imaging signs appear remains an unmet medical need. Former publications suggest that<think> plasminogen activator receptor (suPAR) is a non-specific cancer marker. suPAR was validated for the detection of patients at risk for HCC.METHODS: Afte... | true | note_49907 | note_49907_ soluble urokinase | 824,045 |
note_49907_span_Male_1800000_1850000_mid_mesh | HCC.CONCLUSIONS: | BACKGROUND & AIMS: Early detection of hepatocellular carcinoma (HCC) before imaging signs appear remains an unmet medical need. Former publications suggest that soluble urokinase plasminogen activator receptor (suPAR) is a non-specific cancer marker. suPAR was validated for the detection of patients at risk for HCC.MET... | true | note_49907 | note_49907_ HCC.CONCLUSIONS: | 824,046 |
note_49907_span_Male_1800000_1850000_mid_mesh | potential screening tool | BACKGROUND & AIMS: Early detection of hepatocellular carcinoma (HCC) before imaging signs appear remains an unmet medical need. Former publications suggest that soluble urokinase plasminogen activator receptor (suPAR) is a non-specific cancer marker. suPAR was validated for the detection of patients at risk for HCC.MET... | true | note_49907 | note_49907_ potential screening tool | 824,047 |
note_49908_span_Animals_1800000_1850000_mid_mesh | anti-angiogenic | ETHNOPHARMACOLOGICAL RELEVANCE: Few studies have explored the<think> effects of TCM - even more so, as it applies to cancer treatment research. Heat-clearing and detoxicating TCM is the most frequently used category in the treatment of cancerous tumors, but lacks sufficient validation studies.AIM OF THE STUDY: The pre... | false | note_49908 | note_49908_ anti-angiogenic | 824,048 |
note_49908_span_Animals_1800000_1850000_mid_mesh | zebrafish, | ETHNOPHARMACOLOGICAL RELEVANCE: Few studies have explored the anti-angiogenic effects of TCM - even more so, as it applies to cancer treatment research. Heat-clearing and detoxicating TCM is the most frequently used category in the treatment of cancerous tumors, but lacks sufficient validation studies.AIM OF THE STUDY:... | true | note_49908 | note_49908_ zebrafish, | 824,049 |
note_49908_span_Animals_1800000_1850000_mid_mesh | zebrafish | ETHNOPHARMACOLOGICAL RELEVANCE: Few studies have explored the anti-angiogenic effects of TCM - even more so, as it applies to cancer treatment research. Heat-clearing and detoxicating TCM is the most frequently used category in the treatment of cancerous tumors, but lacks sufficient validation studies.AIM OF THE STUDY:... | true | note_49908 | note_49908_ zebrafish | 824,050 |
note_49909_span_Aged_1800000_1850000_mid_mesh | sufficiency. Zinc deficiency | Plants generally produce more biomass when all nutrients are available in sufficient amounts. In addition to environmental constraints, genetic and developmental factors, such as the transition from vegetative to reproductive growth, restrict maximal biomass yield. Here, we report the peculiar observation that a subset... | true | note_49909 | note_49909_ sufficiency. Zinc deficiency | 824,051 |
note_49909_span_Pregnancy_1800000_1850000_mid_mesh | to reproductive growth, | Plants generally produce more biomass when all nutrients are available in sufficient amounts. In addition to environmental constraints, genetic and developmental factors, such as the transition from vegetative<think> restrict maximal biomass yield. Here, we report the peculiar observation that a subset of Arabidopsis ... | false | note_49909 | note_49909_ to reproductive growth, | 824,052 |
note_49909_span_Pregnancy_1800000_1850000_mid_mesh | nutrient deficiency | Plants generally produce more biomass when all nutrients are available in sufficient amounts. In addition to environmental constraints, genetic and developmental factors, such as the transition from vegetative to reproductive growth, restrict maximal biomass yield. Here, we report the peculiar observation that a subset... | true | note_49909 | note_49909_ nutrient deficiency | 824,053 |
note_49910_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | photothermal therapy | Multifunctional drug delivery nanoplatform (PDPP3T@PSNiAA NPs) based on NIR absorbing semiconducting polymer nanoparticles for pH/NIR light-controllably regulated drug release has been successfully prepared. In this strategy, pH/thermal-sensitive multifunctional polymer polystyrene-b-poly(N-isopropylacrylamide-co-acryl... | false | note_49910 | note_49910_ photothermal therapy | 824,054 |
note_49910_span_Risk Factors_1800000_1850000_mid_mesh | unnecessary drug release | Multifunctional drug delivery nanoplatform (PDPP3T@PSNiAA NPs) based on NIR absorbing semiconducting polymer nanoparticles for pH/NIR light-controllably regulated drug release has been successfully prepared. In this strategy, pH/thermal-sensitive multifunctional polymer polystyrene-b-poly(N-isopropylacrylamide-co-acryl... | false | note_49910 | note_49910_ unnecessary drug release | 824,055 |
note_49911_span_Prognosis_1800000_1850000_mid_mesh | the predictions for | Systems powered by elastic recoil need a latch to prevent motion while a spring is loaded but allow motion during spring recoil. Some jumping animals that rely on elastic recoil use the increasing mechanical advantage of limb extensor muscles to accomplish latching. We examined the ways in which limb morphology affects... | false | note_49911 | note_49911_ the predictions for | 824,057 |
note_49911_span_Animals_1800000_1850000_mid_mesh | jumping animals that | Systems powered by elastic recoil need a latch to prevent motion while a spring is loaded but allow motion during spring recoil. Some<think> rely on elastic recoil use the increasing mechanical advantage of limb extensor muscles to accomplish latching. We examined the ways in which limb morphology affects latching and... | false | note_49911 | note_49911_ jumping animals that | 824,058 |
note_49912_span_Disease Models, Animal_1800000_1850000_mid_mesh | present study performed | The<think> an analysis of the ultrastructural changes induced by andiroba seed oil in the synganglion of Rhipicephalus sanguineus female ticks, aiming to provide scientific grounds to help in the creation of more specific and efficient methods of control. The synganglion consists of a mass of fused nerves externally c... | false | note_49912 | note_49912_ present study performed | 824,059 |
note_49912_span_Disease Models, Animal_1800000_1850000_mid_mesh | female ticks, aiming | The present study performed an analysis of the ultrastructural changes induced by andiroba seed oil in the synganglion of Rhipicephalus sanguineus<think> to provide scientific grounds to help in the creation of more specific and efficient methods of control. The synganglion consists of a mass of fused nerves externall... | true | note_49912 | note_49912_ female ticks, aiming | 824,060 |
note_49912_span_Cell Line, Tumor_1800000_1850000_mid_mesh | female ticks, | The present study performed an analysis of the ultrastructural changes induced by andiroba seed oil in the synganglion of Rhipicephalus sanguineus<think> aiming to provide scientific grounds to help in the creation of more specific and efficient methods of control. The synganglion consists of a mass of fused nerves ex... | false | note_49912 | note_49912_ female ticks, | 824,061 |
note_49913_span_Aged_1800000_1850000_mid_mesh | an actionable therapeutic | The checkpoint protein programmed cell death ligand-1 protein (PD-L1) binds to its receptor (PD-1) activating the PD-L1/PD-1 pathway, an important therapeutic target. There is limited information regarding PD-L1 and PD-1 expression in thymic lesions. Sections from nonneoplastic thymi (n = 20), thymomas World Health Org... | false | note_49913 | note_49913_ an actionable therapeutic | 824,062 |
note_49913_span_Aged_1800000_1850000_mid_mesh | these lesions | The checkpoint protein programmed cell death ligand-1 protein (PD-L1) binds to its receptor (PD-1) activating the PD-L1/PD-1 pathway, an important therapeutic target. There is limited information regarding PD-L1 and PD-1 expression in thymic lesions. Sections from nonneoplastic thymi (n = 20), thymomas World Health Org... | true | note_49913 | note_49913_ these lesions | 824,063 |
note_49913_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | a question as | The checkpoint protein programmed cell death ligand-1 protein (PD-L1) binds to its receptor (PD-1) activating the PD-L1/PD-1 pathway, an important therapeutic target. There is limited information regarding PD-L1 and PD-1 expression in thymic lesions. Sections from nonneoplastic thymi (n = 20), thymomas World Health Org... | false | note_49913 | note_49913_ a question as | 824,064 |
note_49914_span_Aged_1800000_1850000_mid_mesh | Colorectal cancer (CRC) | <think> is a common gastrointestinal cancer with high mortality rate mostly due to metastasis. Ca2+-dependent activator protein for secretion 1 (CAPS1) was originally identified as a soluble factor that reconstitutes Ca2+-dependent secretion. In this study, we discovered a novel role of CAPS1 in CRC metastasis. CAPS1 i... | false | note_49914 | note_49914_Colorectal cancer (CRC) | 824,065 |
note_49914_span_Aged_1800000_1850000_mid_mesh | we discovered a novel | Colorectal cancer (CRC) is a common gastrointestinal cancer with high mortality rate mostly due to metastasis. Ca2+-dependent activator protein for secretion 1 (CAPS1) was originally identified as a soluble factor that reconstitutes Ca2+-dependent secretion. In this study,<think> role of CAPS1 in CRC metastasis. CAPS1... | true | note_49914 | note_49914_ we discovered a novel | 824,066 |
note_49914_span_Aged_1800000_1850000_mid_mesh | signal pathway-mediated EMT | Colorectal cancer (CRC) is a common gastrointestinal cancer with high mortality rate mostly due to metastasis. Ca2+-dependent activator protein for secretion 1 (CAPS1) was originally identified as a soluble factor that reconstitutes Ca2+-dependent secretion. In this study, we discovered a novel role of CAPS1 in CRC met... | true | note_49914 | note_49914_ signal pathway-mediated EMT | 824,067 |
note_49914_span_Adolescent_1800000_1850000_mid_mesh | colorectal cancer | Colorectal cancer (CRC) is a common gastrointestinal cancer with high mortality rate mostly due to metastasis. Ca2+-dependent activator protein for secretion 1 (CAPS1) was originally identified as a soluble factor that reconstitutes Ca2+-dependent secretion. In this study, we discovered a novel role of CAPS1 in CRC met... | false | note_49914 | note_49914_ colorectal cancer | 824,068 |
note_49915_span_Time Factors_1800000_1850000_mid_mesh | CU/1/2014 | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains,<think> and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. The ... | false | note_49915 | note_49915_ CU/1/2014 | 824,069 |
note_49915_span_Time Factors_1800000_1850000_mid_mesh | 2014. | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in<think> ... | true | note_49915 | note_49915_ 2014. | 824,070 |
note_49915_span_Time Factors_1800000_1850000_mid_mesh | the continuing evolution of | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. Th... | true | note_49915 | note_49915_ the continuing evolution of | 824,071 |
note_49915_span_Time Factors_1800000_1850000_mid_mesh | genetic drift and | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. Th... | true | note_49915 | note_49915_ genetic drift and | 824,072 |
note_49915_span_Adolescent_1800000_1850000_mid_mesh | Avian infectious bronchitis | <think> virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. The genome lengths of ... | false | note_49915 | note_49915_Avian infectious bronchitis | 824,073 |
note_49915_span_Adolescent_1800000_1850000_mid_mesh | in chicken populations | Avian infectious bronchitis virus (IBV) is highly prevalent<think> and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. The genome length... | true | note_49915 | note_49915_ in chicken populations | 824,074 |
note_49915_span_Adolescent_1800000_1850000_mid_mesh | worldwide. In this study, we | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry<think> report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. The genome lengths of t... | true | note_49915 | note_49915_ worldwide. In this study, we | 824,075 |
note_49915_span_Adolescent_1800000_1850000_mid_mesh | by genetic drift | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. Th... | true | note_49915 | note_49915_ by genetic drift | 824,076 |
note_49915_span_Adolescent_1800000_1850000_mid_mesh | by genetic recombination | Avian infectious bronchitis virus (IBV) is highly prevalent in chicken populations and is responsible for severe economic losses to poultry industry worldwide. In this study, we report the complete genome sequences of two IBV field strains, CU/1/2014 and CU/4/2014, isolated from vaccinated chickens in Egypt in 2014. Th... | true | note_49915 | note_49915_ by genetic recombination | 824,077 |
note_49916_span_Signal Transduction_1800000_1850000_mid_mesh | Proteomics was | <think> applied here to study Listeria monocytogenes response to gastrointestinal stress. It separated extracted proteins by their isoelectric point (pI) in the first dimension followed by separation by molecular weight in the second dimension on a polyacrylamide gel. L. monocytogenes was grown in an appropriate cultur... | false | note_49916 | note_49916_Proteomics was | 824,078 |
note_49916_span_Mice_1800000_1850000_mid_mesh | by molecular weight | Proteomics was applied here to study Listeria monocytogenes response to gastrointestinal stress. It separated extracted proteins by their isoelectric point (pI) in the first dimension followed by separation<think> in the second dimension on a polyacrylamide gel. L. monocytogenes was grown in an appropriate culture med... | false | note_49916 | note_49916_ by molecular weight | 824,079 |
note_49918_span_Mice_1800000_1850000_mid_mesh | date.METHODS: | BACKGROUND: The National Comprehensive Cancer Network (NCCN) recently revised recommendations for inoperable stage I small cell lung cancer (SCLC), having added stereotactic ablative radiotherapy (SABR)/chemotherapy to the historical paradigm of concurrent conventionally-fractionated radiation therapy (CFRT)/chemothera... | false | note_49918 | note_49918_ date.METHODS: | 824,080 |
note_49920_span_Time Factors_1800000_1850000_mid_mesh | Objectives: The | <think> Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joint (SIJ) scoring system assesses six or five (6/5) semicoronal magnetic resonance imaging (MRI) slices for inflammation/structural lesions in patients with axial spondyloarthritis (axSpA). However, the cartilaginous SIJ compartment may be vi... | false | note_49920 | note_49920_Objectives: The | 824,081 |
note_49920_span_Time Factors_1800000_1850000_mid_mesh | necrosis factor inhibitor | Objectives: The Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joint (SIJ) scoring system assesses six or five (6/5) semicoronal magnetic resonance imaging (MRI) slices for inflammation/structural lesions in patients with axial spondyloarthritis (axSpA). However, the cartilaginous SIJ compartment m... | true | note_49920 | note_49920_ necrosis factor inhibitor | 824,082 |
note_49920_span_Time Factors_1800000_1850000_mid_mesh | at weeks 0, | Objectives: The Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joint (SIJ) scoring system assesses six or five (6/5) semicoronal magnetic resonance imaging (MRI) slices for inflammation/structural lesions in patients with axial spondyloarthritis (axSpA). However, the cartilaginous SIJ compartment m... | true | note_49920 | note_49920_ at weeks 0, | 824,083 |
note_49920_span_Time Factors_1800000_1850000_mid_mesh | 52. | Objectives: The Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joint (SIJ) scoring system assesses six or five (6/5) semicoronal magnetic resonance imaging (MRI) slices for inflammation/structural lesions in patients with axial spondyloarthritis (axSpA). However, the cartilaginous SIJ compartment m... | true | note_49920 | note_49920_ 52. | 824,084 |
note_49920_span_Animals_1800000_1850000_mid_mesh | various lesion types | Objectives: The Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joint (SIJ) scoring system assesses six or five (6/5) semicoronal magnetic resonance imaging (MRI) slices for inflammation/structural lesions in patients with axial spondyloarthritis (axSpA). However, the cartilaginous SIJ compartment m... | false | note_49920 | note_49920_ various lesion types | 824,085 |
note_49921_span_Pregnancy_1800000_1850000_mid_mesh | in diabetic patients. | BACKGROUND: Reconstructive microsurgery is an effective limb-saving option for nonhealing lower extremity wounds<think> However, the ability to predict the future need for amputation is unclear. This article seeks to identify risk factors for amputation following microsurgical free tissue transfer in the diabetic lowe... | false | note_49921 | note_49921_ in diabetic patients. | 824,086 |
note_49922_span_Aged_1800000_1850000_mid_mesh | Delayed-type | <think> hypersensitivity (DTH) reactions are among the common reasons for drug withdrawal from clinical use during the post-marketing stage. Several in vivo methods have been developed to test DTH responses in animal models. They include the local lymph node assay (LLNA) and local lymph node proliferation assay (LLNP).... | false | note_49922 | note_49922_Delayed-type | 824,087 |
note_49922_span_Prognosis_1800000_1850000_mid_mesh | be predictive of | Delayed-type hypersensitivity (DTH) reactions are among the common reasons for drug withdrawal from clinical use during the post-marketing stage. Several in vivo methods have been developed to test DTH responses in animal models. They include the local lymph node assay (LLNA) and local lymph node proliferation assay (L... | false | note_49922 | note_49922_ be predictive of | 824,088 |
note_49923_span_Treatment Outcome_1800000_1850000_mid_mesh | (98.15%) patients were | INTRODUCTION: Electrical isolation of the left atrial appendage (LAA) is an important adjunctive ablation strategy in patients with nonparoxysmal atrial fibrillation (AF). Patients who have impaired LAA contractility following isolation may require long-term oral anticoagulant (OAC) therapy irrespective of their CHADS2... | false | note_49923 | note_49923_ (98.15%) patients were | 824,089 |
note_49923_span_Treatment Outcome_1800000_1850000_mid_mesh | 98% of patients with | INTRODUCTION: Electrical isolation of the left atrial appendage (LAA) is an important adjunctive ablation strategy in patients with nonparoxysmal atrial fibrillation (AF). Patients who have impaired LAA contractility following isolation may require long-term oral anticoagulant (OAC) therapy irrespective of their CHADS2... | true | note_49923 | note_49923_ 98% of patients with | 824,090 |
note_49924_span_Adolescent_1800000_1850000_mid_mesh | our pediatric oncology | A 31-year-old man was referred to an adult urologist for a renal polar mass that measured 7.2 cm in maximum diameter. Robotic assisted complete tumor excision for suspicious renal cell carcinoma was carried out, preserving the rest of the left kidney. Histopathology showed a Wilms tumor (WT) with positive margins. No p... | false | note_49924 | note_49924_ our pediatric oncology | 824,091 |
note_49925_span_Risk Factors_1800000_1850000_mid_mesh | increased risk for | UNLABELLED: College is a time of<think> problematic alcohol use and depressed mood. The comorbidity of these conditions is well documented, but is less well understood, with few interventions designed to prevent or reduce the related consequences. The current study evaluated a web-based personalized intervention for s... | false | note_49925 | note_49925_ increased risk for | 824,092 |
note_49925_span_Cell Line, Tumor_1800000_1850000_mid_mesh | UNLABELLED: | <think> College is a time of increased risk for problematic alcohol use and depressed mood. The comorbidity of these conditions is well documented, but is less well understood, with few interventions designed to prevent or reduce the related consequences. The current study evaluated a web-based personalized interventio... | false | note_49925 | note_49925_UNLABELLED: | 824,093 |
note_49926_span_Cell Line, Tumor_1800000_1850000_mid_mesh | The measles virus is | <think> highly contagious and may hit non-immune populations very hard, as observed on remote islands. The first live-attenuated measles virus vaccine was registered in the United States in 1963, and was imported to the Netherlands from 1968 onwards. Production was taken over by the National Institute for Public Health... | false | note_49926 | note_49926_The measles virus is | 824,094 |
note_49926_span_Cell Line, Tumor_1800000_1850000_mid_mesh | measles virus vaccine was | The measles virus is highly contagious and may hit non-immune populations very hard, as observed on remote islands. The first live-attenuated<think> registered in the United States in 1963, and was imported to the Netherlands from 1968 onwards. Production was taken over by the National Institute for Public Health (RIV... | true | note_49926 | note_49926_ measles virus vaccine was | 824,095 |
note_49926_span_Aged_1800000_1850000_mid_mesh | risk. Recent studies show | The measles virus is highly contagious and may hit non-immune populations very hard, as observed on remote islands. The first live-attenuated measles virus vaccine was registered in the United States in 1963, and was imported to the Netherlands from 1968 onwards. Production was taken over by the National Institute for ... | true | note_49926 | note_49926_ risk. Recent studies show | 824,097 |
note_49927_span_Prognosis_1800000_1850000_mid_mesh | endothelial progenitor | Late<think> cells (LEPCs) are derived from mononuclear cells (MNCs) and are thought to directly incorporate into blood vessels and differentiate into mature endothelial cells (ECs). Using transcriptome and proteome analysis, we identified distinctive LEPC profiles and found that Hedgehog-interacting protein (HIP) is s... | false | note_49927 | note_49927_ endothelial progenitor | 824,098 |
note_49928_span_Mice_1800000_1850000_mid_mesh | BACKGROUND: | <think> Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using UCSC... | false | note_49928 | note_49928_BACKGROUND: | 824,099 |
note_49928_span_Mice_1800000_1850000_mid_mesh | clear.METHODS: | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not<think> In our study, bioinformatic analysis was performed using UCSC Xe... | true | note_49928 | note_49928_ clear.METHODS: | 824,100 |
note_49928_span_Mice_1800000_1850000_mid_mesh | high DNA methylation | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using ... | true | note_49928 | note_49928_ high DNA methylation | 824,101 |
note_49928_span_Mice_1800000_1850000_mid_mesh | expression.CONCLUSION: | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using ... | true | note_49928 | note_49928_ expression.CONCLUSION: | 824,102 |
note_49928_span_Mice_1800000_1850000_mid_mesh | potential biomarker | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using ... | true | note_49928 | note_49928_ potential biomarker | 824,103 |
note_49928_span_Mice_1800000_1850000_mid_mesh | LUAD patients | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using ... | true | note_49928 | note_49928_ LUAD patients | 824,104 |
note_49928_span_Cell Line, Tumor_1800000_1850000_mid_mesh | and prognosis prediction | BACKGROUND: Pituitary homeobox 1 (PITX1) is a member of the PITX gene family which is vital to proper development of early embryo. However, the relationship of PITX1 expression and overall survival (OS) in non-small cell lung cancer (NSCLC) is not clear.METHODS: In our study, bioinformatic analysis was performed using ... | true | note_49928 | note_49928_ and prognosis prediction | 824,106 |
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