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|---|---|---|---|---|---|---|
note_49929_span_Aged_1800000_1850000_mid_mesh | is a later heterotypic | The taxonomic status of Paenibacillus thermophilus was analyzed using genomic and phenotypic approaches. The results of RNA polymerase beta subunit gene sequence comparisons indicated that two type strains of P. thermophilus (DSM 24746T and JCM 17693T) and Paenibacillus macerans ATCC 8244T shared 100 % sequence similar... | false | note_49929 | note_49929_ is a later heterotypic | 824,108 |
note_49929_span_Disease Models, Animal_1800000_1850000_mid_mesh | and phenotypic approaches. | The taxonomic status of Paenibacillus thermophilus was analyzed using genomic<think> The results of RNA polymerase beta subunit gene sequence comparisons indicated that two type strains of P. thermophilus (DSM 24746T and JCM 17693T) and Paenibacillus macerans ATCC 8244T shared 100 % sequence similarity. By whole-genom... | false | note_49929 | note_49929_ and phenotypic approaches. | 824,109 |
note_49929_span_Disease Models, Animal_1800000_1850000_mid_mesh | thermophilus | The taxonomic status of Paenibacillus thermophilus was analyzed using genomic and phenotypic approaches. The results of RNA polymerase beta subunit gene sequence comparisons indicated that two type strains of P. thermophilus (DSM 24746T and JCM 17693T) and Paenibacillus macerans ATCC 8244T shared 100 % sequence similar... | true | note_49929 | note_49929_ thermophilus | 824,110 |
note_49929_span_Disease Models, Animal_1800000_1850000_mid_mesh | Paenibacillus macerans | The taxonomic status of Paenibacillus thermophilus was analyzed using genomic and phenotypic approaches. The results of RNA polymerase beta subunit gene sequence comparisons indicated that two type strains of P. thermophilus (DSM 24746T and JCM 17693T) and Paenibacillus macerans ATCC 8244T shared 100 % sequence similar... | true | note_49929 | note_49929_ Paenibacillus macerans | 824,111 |
note_49930_span_Prognosis_1800000_1850000_mid_mesh | 28-day mortality using | OBJECTIVES: Our study aims at comparing the efficacy and safety of IFN-based therapy (lopinavir/ritonavir, ribavirin, and interferon �-1b) vs. favipiravir (FPV) in a cohort of hospitalized patients with non-critical COVID-19.METHODS: Single center observational study comparing IFN-based therapy (interferon �-1b, ribavi... | false | note_49930 | note_49930_ 28-day mortality using | 824,112 |
note_49930_span_Male_1800000_1850000_mid_mesh | confounders. Patients in | OBJECTIVES: Our study aims at comparing the efficacy and safety of IFN-based therapy (lopinavir/ritonavir, ribavirin, and interferon �-1b) vs. favipiravir (FPV) in a cohort of hospitalized patients with non-critical COVID-19.METHODS: Single center observational study comparing IFN-based therapy (interferon �-1b, ribavi... | false | note_49930 | note_49930_ confounders. Patients in | 824,113 |
note_49931_span_Animals_1800000_1850000_mid_mesh | This study evaluated | <think> the potential toxicity and antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle disease virus (NDV), one of the most serious threats to the poultry industry in the world. Toxicity was assayed on chicken embryo fibroblast (CEF) secondary cultures at concentrations ranging from 0.1 to 1500... | false | note_49931 | note_49931_This study evaluated | 824,114 |
note_49931_span_Animals_1800000_1850000_mid_mesh | the poultry industry | This study evaluated the potential toxicity and antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle disease virus (NDV), one of the most serious threats to<think> in the world. Toxicity was assayed on chicken embryo fibroblast (CEF) secondary cultures at concentrations ranging from 0.1 to 1500... | true | note_49931 | note_49931_ the poultry industry | 824,115 |
note_49931_span_Disease Models, Animal_1800000_1850000_mid_mesh | on chicken embryo fibroblast | This study evaluated the potential toxicity and antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle disease virus (NDV), one of the most serious threats to the poultry industry in the world. Toxicity was assayed<think> (CEF) secondary cultures at concentrations ranging from 0.1 to 1500��g per ... | false | note_49931 | note_49931_ on chicken embryo fibroblast | 824,116 |
note_49933_span_Pregnancy_1800000_1850000_mid_mesh | fat in rats by | INTRODUCTION: A high level of total cholesterol or low-density lipoprotein (LDL) cholesterol is considered the main cause of atherosclerosis and cardiovascular disease. For this reason, experimental atherosclerosis is induced by creating high blood cholesterol in animals. However, the hypothesis that atherosclerotic pr... | false | note_49933 | note_49933_ fat in rats by | 824,117 |
note_49934_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | GBM. Here, we set | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed in adult IDH-wild-type (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently ... | true | note_49934 | note_49934_ GBM. Here, we set | 824,118 |
note_49934_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | of primary brain tumors. In | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed in adult IDH-wild-type (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently ... | true | note_49934 | note_49934_ of primary brain tumors. In | 824,119 |
note_49934_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | addition, we addressed the | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed in adult IDH-wild-type (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently ... | true | note_49934 | note_49934_ addition, we addressed the | 824,120 |
note_49934_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | endothelial proliferation | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed in adult IDH-wild-type (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently ... | true | note_49934 | note_49934_ endothelial proliferation | 824,121 |
note_49934_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | GBM | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed in adult IDH-wild-type (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently ... | true | note_49934 | note_49934_ GBM | 824,122 |
note_49934_span_Male_1800000_1850000_mid_mesh | in adult IDH-wild-type | EGFR amplification (EGFRamp), the combination of gain of chromosome 7 and loss of chromosome 10 (7+/10-), and TERT promoter mutation (pTERTmut) are alterations frequently observed<think> (IDHwt) glioblastoma (GBM). In the absence of endothelial proliferation and/or necrosis, these alterations currently are considered ... | false | note_49934 | note_49934_ in adult IDH-wild-type | 824,123 |
note_49935_span_Time Factors_1800000_1850000_mid_mesh | ages 18-35 and | OBJECTIVE: This study examined the meaning of sickle cell trait and sickle cell trait screening from the lay perspective of African Americans.DESIGN AND METHODS: African Americans (N = 300),<think> unaware of their sickle cell trait status, completed two open-ended questions from a larger survey. One question asked fo... | true | note_49935 | note_49935_ ages 18-35 and | 824,125 |
note_49935_span_Animals_1800000_1850000_mid_mesh | This study examined the | OBJECTIVE:<think> meaning of sickle cell trait and sickle cell trait screening from the lay perspective of African Americans.DESIGN AND METHODS: African Americans (N = 300), ages 18-35 and unaware of their sickle cell trait status, completed two open-ended questions from a larger survey. One question asked for their u... | false | note_49935 | note_49935_ This study examined the | 824,126 |
note_49935_span_Animals_1800000_1850000_mid_mesh | sickle cell trait and | OBJECTIVE: This study examined the meaning of<think> sickle cell trait screening from the lay perspective of African Americans.DESIGN AND METHODS: African Americans (N = 300), ages 18-35 and unaware of their sickle cell trait status, completed two open-ended questions from a larger survey. One question asked for their... | true | note_49935 | note_49935_ sickle cell trait and | 824,127 |
note_49935_span_Animals_1800000_1850000_mid_mesh | African Americans.DESIGN | OBJECTIVE: This study examined the meaning of sickle cell trait and sickle cell trait screening from the lay perspective of<think> AND METHODS: African Americans (N = 300), ages 18-35 and unaware of their sickle cell trait status, completed two open-ended questions from a larger survey. One question asked for their un... | true | note_49935 | note_49935_ African Americans.DESIGN | 824,128 |
note_49935_span_Animals_1800000_1850000_mid_mesh | cell trait screening | OBJECTIVE: This study examined the meaning of sickle cell trait and sickle cell trait screening from the lay perspective of African Americans.DESIGN AND METHODS: African Americans (N = 300), ages 18-35 and unaware of their sickle cell trait status, completed two open-ended questions from a larger survey. One question a... | true | note_49935 | note_49935_ cell trait screening | 824,129 |
note_49936_span_Mice_1800000_1850000_mid_mesh | a molecular probe | Dansyl-derivatized, triazole-linked, glucopyranosyl conjugates, (5F)LOH, (2F)LOH, (1F)LOH, and (0F)LOH were synthesized and characterized. While the (5F)LOH acts as<think> for CN(-), (2F)LOH, (1F)LOH, and (0F)LOH acts as control molecules. The reactivity of CN(-) toward (5F)LOH has been elicited through the changes ob... | false | note_49936 | note_49936_ a molecular probe | 824,130 |
note_49936_span_Cell Line, Tumor_1800000_1850000_mid_mesh | 1 cellulose | Dansyl-derivatized, triazole-linked, glucopyranosyl conjugates, (5F)LOH, (2F)LOH, (1F)LOH, and (0F)LOH were synthesized and characterized. While the (5F)LOH acts as a molecular probe for CN(-), (2F)LOH, (1F)LOH, and (0F)LOH acts as control molecules. The reactivity of CN(-) toward (5F)LOH has been elicited through the ... | false | note_49936 | note_49936_ 1 cellulose | 824,131 |
note_49936_span_Cell Line, Tumor_1800000_1850000_mid_mesh | DFT computational study. | Dansyl-derivatized, triazole-linked, glucopyranosyl conjugates, (5F)LOH, (2F)LOH, (1F)LOH, and (0F)LOH were synthesized and characterized. While the (5F)LOH acts as a molecular probe for CN(-), (2F)LOH, (1F)LOH, and (0F)LOH acts as control molecules. The reactivity of CN(-) toward (5F)LOH has been elicited through the ... | true | note_49936 | note_49936_ DFT computational study. | 824,132 |
note_49937_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | this study was | The goal of<think> to compare dysphagia phenotypes in low and high copy number (LCN and HCN) transgenic superoxide dismutase 1 (SOD1) mouse models of ALS to accelerate the discovery of novel and effective treatments for dysphagia and early amyotrophic lateral sclerosis (ALS) diagnosis. Clinicopathological features of ... | false | note_49937 | note_49937_ this study was | 824,133 |
note_49937_span_Mice_1800000_1850000_mid_mesh | (SOD1) mouse models | The goal of this study was to compare dysphagia phenotypes in low and high copy number (LCN and HCN) transgenic superoxide dismutase 1<think> of ALS to accelerate the discovery of novel and effective treatments for dysphagia and early amyotrophic lateral sclerosis (ALS) diagnosis. Clinicopathological features of dysph... | false | note_49937 | note_49937_ (SOD1) mouse models | 824,134 |
note_49938_span_Mice_1800000_1850000_mid_mesh | species. Molecular genetic | Sainfoin (Onobrychis viciifolia) is a perennial forage legume with great potential for use in sustainable agriculture due to its low input requirements, good drought tolerance, and production of forage rich in polyphenolic compounds, which are beneficial for animal health. However, its distribution and cultivation are ... | false | note_49938 | note_49938_ species. Molecular genetic | 824,135 |
note_49938_span_Aged_1800000_1850000_mid_mesh | a biparental | Sainfoin (Onobrychis viciifolia) is a perennial forage legume with great potential for use in sustainable agriculture due to its low input requirements, good drought tolerance, and production of forage rich in polyphenolic compounds, which are beneficial for animal health. However, its distribution and cultivation are ... | false | note_49938 | note_49938_ a biparental | 824,136 |
note_49939_span_Adolescent_1800000_1850000_mid_mesh | in hormone response | Galactinol synthase (GolS) is a key enzyme in raffinose family oligosaccharide (RFO) biosynthesis. The finding that GolS accumulates in plants exposed to abiotic stresses indicates RFOs function in environmental adaptation. However, the evolutionary relationships and biological functions of GolS family in rapeseed (Bra... | false | note_49939 | note_49939_ in hormone response | 824,137 |
note_49939_span_Signal Transduction_1800000_1850000_mid_mesh | genes in hormone response in | Galactinol synthase (GolS) is a key enzyme in raffinose family oligosaccharide (RFO) biosynthesis. The finding that GolS accumulates in plants exposed to abiotic stresses indicates RFOs function in environmental adaptation. However, the evolutionary relationships and biological functions of GolS family in rapeseed (Bra... | false | note_49939 | note_49939_ genes in hormone response in | 824,138 |
note_49940_span_Risk Factors_1800000_1850000_mid_mesh | homeostasis. However, how | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue<think> post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruiting Smurf E3 ubiqu... | true | note_49940 | note_49940_ homeostasis. However, how | 824,139 |
note_49940_span_Risk Factors_1800000_1850000_mid_mesh | VprBP negatively controls | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ VprBP negatively controls | 824,140 |
note_49940_span_Risk Factors_1800000_1850000_mid_mesh | I receptor (T�RI). | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ I receptor (T�RI). | 824,141 |
note_49940_span_Risk Factors_1800000_1850000_mid_mesh | cells, depletion | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ cells, depletion | 824,142 |
note_49940_span_Risk Factors_1800000_1850000_mid_mesh | expression, and | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ expression, and | 824,143 |
note_49940_span_Male_1800000_1850000_mid_mesh | the mouse embryo VprBP | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ the mouse embryo VprBP | 824,144 |
note_49940_span_Male_1800000_1850000_mid_mesh | zebrafish embryogenesis. | The transforming growth factor-� (TGF-�) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-� family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-�/Smad signaling by recruit... | true | note_49940 | note_49940_ zebrafish embryogenesis. | 824,145 |
note_49941_span_Prognosis_1800000_1850000_mid_mesh | multiple sclerosis (MS) | PURPOSE: To measure the longitudinal change in<think> lesion susceptibility using quantitative susceptibility mapping (QSM).MATERIALS AND METHODS: The study was approved by our Institutional Review Board. Longitudinal changes in quantitative susceptibility values of new enhanced-with-Gd MS lesions were measured at bas... | false | note_49941 | note_49941_ multiple sclerosis (MS) | 824,146 |
note_49942_span_Treatment Outcome_1800000_1850000_mid_mesh | long-term radon | In more than 1500 schools and preschool facilities,<think> measurement was carried out in the last 3 y. The negative effect of thermal retrofitting on the resulting long-term radon averages is evident. In some of the facilities, low ventilation rates and correspondingly high radon levels were found, so it was recommen... | false | note_49942 | note_49942_ long-term radon | 824,147 |
note_49942_span_Treatment Outcome_1800000_1850000_mid_mesh | of thermal retrofitting | In more than 1500 schools and preschool facilities, long-term radon measurement was carried out in the last 3 y. The negative effect<think> on the resulting long-term radon averages is evident. In some of the facilities, low ventilation rates and correspondingly high radon levels were found, so it was recommended to c... | true | note_49942 | note_49942_ of thermal retrofitting | 824,148 |
note_49942_span_Treatment Outcome_1800000_1850000_mid_mesh | for investigation of radon | In more than 1500 schools and preschool facilities, long-term radon measurement was carried out in the last 3 y. The negative effect of thermal retrofitting on the resulting long-term radon averages is evident. In some of the facilities, low ventilation rates and correspondingly high radon levels were found, so it was ... | true | note_49942 | note_49942_ for investigation of radon | 824,149 |
note_49942_span_Adolescent_1800000_1850000_mid_mesh | in school and preschool | In more than 1500 schools and preschool facilities, long-term radon measurement was carried out in the last 3 y. The negative effect of thermal retrofitting on the resulting long-term radon averages is evident. In some of the facilities, low ventilation rates and correspondingly high radon levels were found, so it was ... | false | note_49942 | note_49942_ in school and preschool | 824,150 |
note_49943_span_Animals_1800000_1850000_mid_mesh | between genomic loci. | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities<think> Dynamical simulations using this landscape lead to cylindrical, helically twisted struct... | true | note_49943 | note_49943_ between genomic loci. | 824,151 |
note_49943_span_Animals_1800000_1850000_mid_mesh | ideal chromosome landscape | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities between genomic loci. Dynamical simulations using this landscape lead to cylindrical, helically ... | true | note_49943 | note_49943_ ideal chromosome landscape | 824,152 |
note_49943_span_Animals_1800000_1850000_mid_mesh | domain interaction strength. | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities between genomic loci. Dynamical simulations using this landscape lead to cylindrical, helically ... | true | note_49943 | note_49943_ domain interaction strength. | 824,153 |
note_49943_span_Time Factors_1800000_1850000_mid_mesh | behaviors. The phase diagram | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities between genomic loci. Dynamical simulations using this landscape lead to cylindrical, helically ... | true | note_49943 | note_49943_ behaviors. The phase diagram | 824,154 |
note_49943_span_Time Factors_1800000_1850000_mid_mesh | at temperatures above | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities between genomic loci. Dynamical simulations using this landscape lead to cylindrical, helically ... | true | note_49943 | note_49943_ at temperatures above | 824,155 |
note_49943_span_Time Factors_1800000_1850000_mid_mesh | strength. | We derive an unbiased information theoretic energy landscape for chromosomes at metaphase using a maximum entropy approach that accurately reproduces the details of the experimentally measured pairwise contact probabilities between genomic loci. Dynamical simulations using this landscape lead to cylindrical, helically ... | true | note_49943 | note_49943_ strength. | 824,156 |
note_49944_span_Time Factors_1800000_1850000_mid_mesh | BACKGROUND: | <think> We examined outcomes of patient-initiated second opinions provided by a national second-opinion program.METHODS: We independently examined data collected from January 1, 2011 to December 31, 2012 from a second-opinion program (Best Doctors, Inc.) that allows employee-beneficiaries to request free second opinion... | false | note_49944 | note_49944_BACKGROUND: | 824,157 |
note_49944_span_Time Factors_1800000_1850000_mid_mesh | 2011 to December | BACKGROUND: We examined outcomes of patient-initiated second opinions provided by a national second-opinion program.METHODS: We independently examined data collected from January 1,<think> 31, 2012 from a second-opinion program (Best Doctors, Inc.) that allows employee-beneficiaries to request free second opinions. Cl... | true | note_49944 | note_49944_ 2011 to December | 824,158 |
note_49944_span_Aged_1800000_1850000_mid_mesh | BACKGROUND: We examined | <think> outcomes of patient-initiated second opinions provided by a national second-opinion program.METHODS: We independently examined data collected from January 1, 2011 to December 31, 2012 from a second-opinion program (Best Doctors, Inc.) that allows employee-beneficiaries to request free second opinions. Clinical ... | false | note_49944 | note_49944_BACKGROUND: We examined | 824,159 |
note_49944_span_Aged_1800000_1850000_mid_mesh | second opinions provided | BACKGROUND: We examined outcomes of patient-initiated<think> by a national second-opinion program.METHODS: We independently examined data collected from January 1, 2011 to December 31, 2012 from a second-opinion program (Best Doctors, Inc.) that allows employee-beneficiaries to request free second opinions. Clinical i... | true | note_49944 | note_49944_ second opinions provided | 824,160 |
note_49944_span_Aged_1800000_1850000_mid_mesh | clinical outcomes, such as | BACKGROUND: We examined outcomes of patient-initiated second opinions provided by a national second-opinion program.METHODS: We independently examined data collected from January 1, 2011 to December 31, 2012 from a second-opinion program (Best Doctors, Inc.) that allows employee-beneficiaries to request free second opi... | true | note_49944 | note_49944_ clinical outcomes, such as | 824,161 |
note_49945_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | Importance: Rib fractures are | <think> sustained by nearly 15% of patients who experience trauma and are associated with significant morbidity and mortality. Evidence-based practice (EBP) rib fracture management guidelines and treatment algorithms have been published. However, few studies have evaluated trauma center adherence to EBP or the clinical... | false | note_49945 | note_49945_Importance: Rib fractures are | 824,162 |
note_49945_span_Signal Transduction_1800000_1850000_mid_mesh | rib fractures | Importance: Rib fractures are sustained by nearly 15% of patients who experience trauma and are associated with significant morbidity and mortality. Evidence-based practice (EBP) rib fracture management guidelines and treatment algorithms have been published. However, few studies have evaluated trauma center adherence ... | false | note_49945 | note_49945_ rib fractures | 824,163 |
note_49946_span_Animals_1800000_1850000_mid_mesh | treat inflammatory processes | There is a well known link between inflammation and cancer during initiation, propagation and metastasis. Urera aurantiaca (UA) Wedd. (Urticaceae) is a medicinal plant used in traditional medicine to<think> with proven in vivo antiinflammatory and antinociceptive effects. The effects of a methanolic extract (UA) and a... | false | note_49946 | note_49946_ treat inflammatory processes | 824,164 |
note_49946_span_Animals_1800000_1850000_mid_mesh | antiinflammatory action. | There is a well known link between inflammation and cancer during initiation, propagation and metastasis. Urera aurantiaca (UA) Wedd. (Urticaceae) is a medicinal plant used in traditional medicine to treat inflammatory processes with proven in vivo antiinflammatory and antinociceptive effects. The effects of a methanol... | true | note_49946 | note_49946_ antiinflammatory action. | 824,165 |
note_49947_span_Prognosis_1800000_1850000_mid_mesh | (overall survival and | PURPOSE: Patients with respiratory failure associated with neurological dysfunction often require mechanical ventilator support, which poses increased economic burden and ventilator-associated complications. A diaphragm pacing system (DPS) is an implanted device that provides respiratory support for such patients. In t... | false | note_49947 | note_49947_ (overall survival and | 824,166 |
note_49947_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | MEDLINE, | PURPOSE: Patients with respiratory failure associated with neurological dysfunction often require mechanical ventilator support, which poses increased economic burden and ventilator-associated complications. A diaphragm pacing system (DPS) is an implanted device that provides respiratory support for such patients. In t... | true | note_49947 | note_49947_ MEDLINE, | 824,167 |
note_49948_span_Pregnancy_1800000_1850000_mid_mesh | three children, | Hemophagoytic lymphohistiocytosis (HLH) is a rare life-threatening disorder caused by overactivation of the immune system, associated with infections, autoimmune disorders, and malignancies. The pathological hallmark of HLH is phagocytosis of blood cells and platelets by activated macrophages and histiocytes. In this r... | false | note_49948 | note_49948_ three children, | 824,168 |
note_49948_span_Cell Line, Tumor_1800000_1850000_mid_mesh | drug-lymphocyte stimulation | Hemophagoytic lymphohistiocytosis (HLH) is a rare life-threatening disorder caused by overactivation of the immune system, associated with infections, autoimmune disorders, and malignancies. The pathological hallmark of HLH is phagocytosis of blood cells and platelets by activated macrophages and histiocytes. In this r... | false | note_49948 | note_49948_ drug-lymphocyte stimulation | 824,169 |
note_49950_span_Time Factors_1800000_1850000_mid_mesh | Rwandan adults during a | Plasmodium falciparum infection can result in severe disease that is associated with elevated inflammation and vital organ dysfunction; however, malaria-endemic residents gain protection from lethal outcomes and manifest only mild symptoms during infection. To characterize host responses associated with this more effec... | false | note_49950 | note_49950_ Rwandan adults during a | 824,170 |
note_49950_span_Time Factors_1800000_1850000_mid_mesh | response to malaria. | Plasmodium falciparum infection can result in severe disease that is associated with elevated inflammation and vital organ dysfunction; however, malaria-endemic residents gain protection from lethal outcomes and manifest only mild symptoms during infection. To characterize host responses associated with this more effec... | true | note_49950 | note_49950_ response to malaria. | 824,171 |
note_49950_span_Disease Models, Animal_1800000_1850000_mid_mesh | murine model of | Plasmodium falciparum infection can result in severe disease that is associated with elevated inflammation and vital organ dysfunction; however, malaria-endemic residents gain protection from lethal outcomes and manifest only mild symptoms during infection. To characterize host responses associated with this more effec... | false | note_49950 | note_49950_ murine model of | 824,172 |
note_49951_span_Disease Models, Animal_1800000_1850000_mid_mesh | tsutsugamushi disease, | Scrub typhus, also known as<think> is caused by Orientia sp. and approximately 1 million new cases are reported annually. This article discusses the importance of scrub typhus and its clinical presentation, diagnosis, treatment, and prevention | false | note_49951 | note_49951_ tsutsugamushi disease, | 824,173 |
note_49952_span_Treatment Outcome_1800000_1850000_mid_mesh | budding yeast that differ | The extent to which carbon flux is directed toward fermentation versus respiration differs between cell types and environmental conditions. Understanding the basic cellular processes governing carbon flux is challenged by the complexity of the metabolic and regulatory networks. To reveal the genetic basis for natural d... | true | note_49952 | note_49952_ budding yeast that differ | 824,174 |
note_49952_span_Disease Models, Animal_1800000_1850000_mid_mesh | budding yeast that | The extent to which carbon flux is directed toward fermentation versus respiration differs between cell types and environmental conditions. Understanding the basic cellular processes governing carbon flux is challenged by the complexity of the metabolic and regulatory networks. To reveal the genetic basis for natural d... | false | note_49952 | note_49952_ budding yeast that | 824,175 |
note_49953_span_Pregnancy_1800000_1850000_mid_mesh | of HIV infection | The chronicity<think> and the use of antiretroviral therapy among all individuals living with HIV necessitate new treatment strategies. Alternatives to lifelong tri-therapy treatment are under investigation with the aim to improve the quality of life of patients. New therapies with longer half-lives or � biological � ... | false | note_49953 | note_49953_ of HIV infection | 824,176 |
note_49954_span_Disease Models, Animal_1800000_1850000_mid_mesh | mouth disease virus | Foot and<think> (FMDV) is a highly contagious pathogen propagating among cloven-hoofed animals. As a major immunogenic protein, VP1 plays a pivotal role in the induction of neutralizing antibodies, which therefore is an ideal target for developing subunit vaccines. In current study, four prokaryotic expression clones ... | false | note_49954 | note_49954_ mouth disease virus | 824,177 |
note_49954_span_Disease Models, Animal_1800000_1850000_mid_mesh | of guinea pigs | Foot and mouth disease virus (FMDV) is a highly contagious pathogen propagating among cloven-hoofed animals. As a major immunogenic protein, VP1 plays a pivotal role in the induction of neutralizing antibodies, which therefore is an ideal target for developing subunit vaccines. In current study, four prokaryotic expres... | true | note_49954 | note_49954_ of guinea pigs | 824,178 |
note_49955_span_Male_1800000_1850000_mid_mesh | This study assessed the | <think> utility of ultrasound-guided lateral transversus abdominis plane (TAP) block combined with rectus sheath (RS) block for peritoneal dialysis catheter placement surgery. Thirty consecutive patients with end-stage renal disease scheduled to have peritoneal dialysis catheter placement received a left lateral TAP bl... | false | note_49955 | note_49955_This study assessed the | 824,179 |
note_49955_span_Male_1800000_1850000_mid_mesh | end-stage renal disease | This study assessed the utility of ultrasound-guided lateral transversus abdominis plane (TAP) block combined with rectus sheath (RS) block for peritoneal dialysis catheter placement surgery. Thirty consecutive patients with<think> scheduled to have peritoneal dialysis catheter placement received a left lateral TAP bl... | true | note_49955 | note_49955_ end-stage renal disease | 824,180 |
note_49955_span_Treatment Outcome_1800000_1850000_mid_mesh | anesthetic drugs. | This study assessed the utility of ultrasound-guided lateral transversus abdominis plane (TAP) block combined with rectus sheath (RS) block for peritoneal dialysis catheter placement surgery. Thirty consecutive patients with end-stage renal disease scheduled to have peritoneal dialysis catheter placement received a lef... | true | note_49955 | note_49955_ anesthetic drugs. | 824,181 |
note_49955_span_Treatment Outcome_1800000_1850000_mid_mesh | anesthetic modality | This study assessed the utility of ultrasound-guided lateral transversus abdominis plane (TAP) block combined with rectus sheath (RS) block for peritoneal dialysis catheter placement surgery. Thirty consecutive patients with end-stage renal disease scheduled to have peritoneal dialysis catheter placement received a lef... | true | note_49955 | note_49955_ anesthetic modality | 824,182 |
note_49955_span_Treatment Outcome_1800000_1850000_mid_mesh | placement surgery | This study assessed the utility of ultrasound-guided lateral transversus abdominis plane (TAP) block combined with rectus sheath (RS) block for peritoneal dialysis catheter placement surgery. Thirty consecutive patients with end-stage renal disease scheduled to have peritoneal dialysis catheter placement received a lef... | true | note_49955 | note_49955_ placement surgery | 824,183 |
note_49956_span_Cell Line, Tumor_1800000_1850000_mid_mesh | in plant defence. | Phytic acid (inositol hexakisphosphate, InsP6 ) is an important phosphate store and signal molecule necessary for maintenance of basal resistance to plant pathogens. Arabidopsis thaliana ('arabidopsis') has three genes encoding myo-inositol phosphate synthases (IPS1-3), the enzymes that catalyse conversion of glucose-6... | true | note_49956 | note_49956_ in plant defence. | 824,184 |
note_49958_span_Prognosis_1800000_1850000_mid_mesh | of neuropathy | Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately eva... | true | note_49958 | note_49958_ of neuropathy | 824,185 |
note_49958_span_Prognosis_1800000_1850000_mid_mesh | electrophysiologic findings | Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately eva... | true | note_49958 | note_49958_ electrophysiologic findings | 824,186 |
note_49958_span_Mice_1800000_1850000_mid_mesh | (M/F = 1/2; | Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately eva... | true | note_49958 | note_49958_ (M/F = 1/2; | 824,187 |
note_49958_span_Mice_1800000_1850000_mid_mesh | (16.4 � 5.6 ng/mL) | Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately eva... | true | note_49958 | note_49958_ (16.4 � 5.6 ng/mL) | 824,188 |
note_49958_span_Mice_1800000_1850000_mid_mesh | (40.4 � 4.7 ng/mL) | Copper deficiency (hypocupremia) or toxicosis (hypercupremia) may cause disorders of central and peripheral nervous systems. Hypocupremia causes myeloneuropathy resembling vitamin B12 deficiency. However, the clinical manifestations, particularly peripheral neuropathy (PN), of hypercupremia have not been adequately eva... | true | note_49958 | note_49958_ (40.4 � 4.7 ng/mL) | 824,189 |
note_49959_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | effective, acceptable, | OBJECTIVE: To determine whether Scrambler therapy is an<think> and feasible treatment of persistent central neuropathic pain in patients with neuromyelitis optica spectrum disorder (NMOSD) and to explore the effect of Scrambler therapy on co-occurring symptoms.METHODS: We conducted a randomized single-blind, sham-cont... | false | note_49959 | note_49959_ effective, acceptable, | 824,190 |
note_49960_span_Signal Transduction_1800000_1850000_mid_mesh | supraclavicular nerve block. | Background: Supraclavicular nerve block is a popular approach for anaesthesia for upper limb surgeries. Conventional methods for evaluation of block success are time consuming and need patient cooperation. The aim of this study was to evaluate whether the perfusion index (PI) can be used to predict and provide a cut-of... | false | note_49960 | note_49960_ supraclavicular nerve block. | 824,191 |
note_49960_span_Cell Line, Tumor_1800000_1850000_mid_mesh | for anaesthesia for | Background: Supraclavicular nerve block is a popular approach<think> upper limb surgeries. Conventional methods for evaluation of block success are time consuming and need patient cooperation. The aim of this study was to evaluate whether the perfusion index (PI) can be used to predict and provide a cut-off value for ... | false | note_49960 | note_49960_ for anaesthesia for | 824,192 |
note_49960_span_Cell Line, Tumor_1800000_1850000_mid_mesh | this study was to | Background: Supraclavicular nerve block is a popular approach for anaesthesia for upper limb surgeries. Conventional methods for evaluation of block success are time consuming and need patient cooperation. The aim of<think> evaluate whether the perfusion index (PI) can be used to predict and provide a cut-off value fo... | true | note_49960 | note_49960_ this study was to | 824,193 |
note_49961_span_Surveys and Questionnaires_1800000_1850000_mid_mesh | a meta-analysis | OBJECTIVES: To determine whether concomitant mitral stenosis (MS) impairs outcomes after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS), we performed<think> of currently available evidence.METHODS: To identify all observational comparative studies of outcomes after TAVI for... | false | note_49961 | note_49961_ a meta-analysis | 824,194 |
note_49961_span_Male_1800000_1850000_mid_mesh | (MEDLINE and | OBJECTIVES: To determine whether concomitant mitral stenosis (MS) impairs outcomes after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS), we performed a meta-analysis of currently available evidence.METHODS: To identify all observational comparative studies of outcomes after ... | false | note_49961 | note_49961_ (MEDLINE and | 824,195 |
note_49961_span_Male_1800000_1850000_mid_mesh | in patients with | OBJECTIVES: To determine whether concomitant mitral stenosis (MS) impairs outcomes after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS), we performed a meta-analysis of currently available evidence.METHODS: To identify all observational comparative studies of outcomes after ... | true | note_49961 | note_49961_ in patients with | 824,196 |
note_49962_span_Male_1800000_1850000_mid_mesh | in mouse polyclonal | We studied carbohydrate specificity and isotypes of antibodies to BSA-conjugated tetrasaccharide, a repeating unit of the capsular polysaccharide of Streptococcus pneumoniae serotype 14,<think> sera and hybridoma-synthesized products. Natural IgM antibodies to the tetrasaccharide containing epitopes similar to surface... | false | note_49962 | note_49962_ in mouse polyclonal | 824,197 |
note_49962_span_Cell Line, Tumor_1800000_1850000_mid_mesh | and hybridoma-synthesized | We studied carbohydrate specificity and isotypes of antibodies to BSA-conjugated tetrasaccharide, a repeating unit of the capsular polysaccharide of Streptococcus pneumoniae serotype 14, in mouse polyclonal sera<think> products. Natural IgM antibodies to the tetrasaccharide containing epitopes similar to surface carbo... | false | note_49962 | note_49962_ and hybridoma-synthesized | 824,198 |
note_49963_span_Adolescent_1800000_1850000_mid_mesh | active phase of | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica... | false | note_49963 | note_49963_ active phase of | 824,199 |
note_49963_span_Adolescent_1800000_1850000_mid_mesh | Experimental anatomical | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica... | true | note_49963 | note_49963_ Experimental anatomical | 824,200 |
note_49963_span_Adolescent_1800000_1850000_mid_mesh | bines showed | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica... | true | note_49963 | note_49963_ bines showed | 824,201 |
note_49963_span_Adolescent_1800000_1850000_mid_mesh | monocyclic transient system | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica... | true | note_49963 | note_49963_ monocyclic transient system | 824,202 |
note_49963_span_Adolescent_1800000_1850000_mid_mesh | paracitic. | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica... | true | note_49963 | note_49963_ paracitic. | 824,203 |
note_49963_span_Time Factors_1800000_1850000_mid_mesh | Georgian flora is represented | <think> by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of the research were: sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica Pojark. and revealing... | false | note_49963 | note_49963_Georgian flora is represented | 824,204 |
note_49963_span_Time Factors_1800000_1850000_mid_mesh | the research were: | Georgian flora is represented by about 4150 plant species. Many important alkaloid-containing plant species and among of them are species Buxus L. of genus in Adjara. The aims of<think> sequential screening of the plants for the consistence of alkaloids; Study of anatomical characteristics of Buxus colchica Pojark. an... | true | note_49963 | note_49963_ the research were: | 824,205 |
note_49964_span_Pregnancy_1800000_1850000_mid_mesh | hippocampal newborn cells, | Stroke is one of the leading causes of long-term disabilities worldwide. Although exposure to an enriched environment (EE) initiated in the acute phase after stroke has neuroprotective effects and improves stroke outcome, it remains unclear whether EE has positive effects when started in a delayed time frame. Here we s... | false | note_49964 | note_49964_ hippocampal newborn cells, | 824,207 |
note_49964_span_Risk Factors_1800000_1850000_mid_mesh | Stroke is | <think> one of the leading causes of long-term disabilities worldwide. Although exposure to an enriched environment (EE) initiated in the acute phase after stroke has neuroprotective effects and improves stroke outcome, it remains unclear whether EE has positive effects when started in a delayed time frame. Here we sho... | false | note_49964 | note_49964_Stroke is | 824,208 |
note_49965_span_Treatment Outcome_1800000_1850000_mid_mesh | of treatment. | NEW FINDINGS: What is the central question of this study? What are the temporal responses of mitochondrial respiration and mitochondrial responsivity to insulin in soleus muscle fibres from mice during the development of obesity and insulin resistance? What is the main finding and its importance? Short- and long-term f... | false | note_49965 | note_49965_ of treatment. | 824,209 |
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